KR101222904B1
(ko)
|
1993-07-19 |
2013-01-17 |
안지오테크 파마슈티칼즈, 인코포레이티드 |
항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법
|
US20030203976A1
(en)
|
1993-07-19 |
2003-10-30 |
William L. Hunter |
Anti-angiogenic compositions and methods of use
|
KR100361933B1
(ko)
*
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
US5919455A
(en)
*
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
US5730990A
(en)
*
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
US7597886B2
(en)
*
|
1994-11-07 |
2009-10-06 |
Human Genome Sciences, Inc. |
Tumor necrosis factor-gamma
|
US7820798B2
(en)
*
|
1994-11-07 |
2010-10-26 |
Human Genome Sciences, Inc. |
Tumor necrosis factor-gamma
|
US5932462A
(en)
*
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
US7429646B1
(en)
|
1995-06-05 |
2008-09-30 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor-like 2
|
EP0741187A2
(en)
*
|
1995-05-05 |
1996-11-06 |
F. Hoffmann-La Roche Ag |
Recombinant obese (Ob) proteins
|
ZA963530B
(en)
*
|
1995-05-05 |
1996-11-05 |
Hoffmann La Roche |
Recombinant obese (ob) proteins
|
US7048906B2
(en)
*
|
1995-05-17 |
2006-05-23 |
Cedars-Sinai Medical Center |
Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
|
WO1997022371A1
(en)
*
|
1995-12-18 |
1997-06-26 |
Collagen Corporation |
Crosslinked polymer compositions and methods for their use
|
US7883693B2
(en)
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
US6441025B2
(en)
|
1996-03-12 |
2002-08-27 |
Pg-Txl Company, L.P. |
Water soluble paclitaxel derivatives
|
US7357927B2
(en)
*
|
1996-03-12 |
2008-04-15 |
Human Genome Sciences, Inc. |
Death domain containing receptors
|
HU226646B1
(en)
*
|
1996-03-12 |
2009-05-28 |
Pg Txl Company |
Water soluble pharmaceutical compositions containing taxane derivatives
|
WO1997033904A1
(en)
|
1996-03-12 |
1997-09-18 |
Human Genome Sciences, Inc. |
Death domain containing receptors
|
US6713061B1
(en)
|
1996-03-12 |
2004-03-30 |
Human Genome Sciences, Inc. |
Death domain containing receptors
|
US7964190B2
(en)
*
|
1996-03-22 |
2011-06-21 |
Human Genome Sciences, Inc. |
Methods and compositions for decreasing T-cell activity
|
US6635743B1
(en)
|
1996-03-22 |
2003-10-21 |
Human Genome Sciences, Inc. |
Apoptosis inducing molecule II and methods of use
|
US6025324A
(en)
*
|
1996-05-15 |
2000-02-15 |
Hoffmann-La Roche Inc. |
Pegylated obese (ob) protein compositions
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
AU3908597A
(en)
*
|
1996-08-02 |
1998-02-25 |
Ortho-Mcneil Pharmaceutical, Inc. |
Polypeptides having a single covalently bound n-terminal water-soluble polymer
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US8212004B2
(en)
*
|
1999-03-02 |
2012-07-03 |
Human Genome Sciences, Inc. |
Neutrokine-alpha fusion proteins
|
US6812327B1
(en)
*
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
DE69821338T2
(de)
|
1997-02-21 |
2004-10-21 |
Genentech Inc |
Antikörperfragment-polymerkonjugate
|
US6872568B1
(en)
|
1997-03-17 |
2005-03-29 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5 antibodies
|
US20040136951A1
(en)
*
|
1997-03-17 |
2004-07-15 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5
|
US20050233958A1
(en)
*
|
1997-03-17 |
2005-10-20 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5
|
US20080248046A1
(en)
*
|
1997-03-17 |
2008-10-09 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5
|
NZ508381A
(en)
*
|
1997-03-17 |
2002-09-27 |
Human Genome Sciences Inc |
Antibodies, antagonists and agonists of the death domain containing receptor 5 (DR5)
|
US5900402A
(en)
*
|
1997-05-29 |
1999-05-04 |
Enzon, Inc. |
Method of reducing side effects associated with administration of oxygen-carrying proteins
|
US6284246B1
(en)
|
1997-07-30 |
2001-09-04 |
The Procter & Gamble Co. |
Modified polypeptides with high activity and reduced allergenicity
|
KR100364938B1
(ko)
*
|
1997-09-18 |
2002-12-18 |
에프. 호프만-라 로슈 아게 |
만성 씨형 간염의 치료를 위한 인테페론-알파와 아만타딘을 함유한 약제
|
KR20010015856A
(ko)
*
|
1997-12-12 |
2001-02-26 |
마크로메드 인코퍼레이션 |
단백질 변성용으로 헤테로 작용기를 가진 별 모양의폴리(에틸렌글리콜)
|
US6180095B1
(en)
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
EP1037649B1
(en)
|
1997-12-17 |
2009-09-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US5965119A
(en)
|
1997-12-30 |
1999-10-12 |
Enzon, Inc. |
Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
|
US6624142B2
(en)
|
1997-12-30 |
2003-09-23 |
Enzon, Inc. |
Trimethyl lock based tetrapartate prodrugs
|
US7005504B2
(en)
*
|
1998-01-22 |
2006-02-28 |
Genentech, Inc. |
Antibody fragment-peg conjugates
|
US6468532B1
(en)
|
1998-01-22 |
2002-10-22 |
Genentech, Inc. |
Methods of treating inflammatory diseases with anti-IL-8 antibody fragment-polymer conjugates
|
US6458355B1
(en)
|
1998-01-22 |
2002-10-01 |
Genentech, Inc. |
Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates
|
US6066673A
(en)
*
|
1998-03-12 |
2000-05-23 |
The Procter & Gamble Company |
Enzyme inhibitors
|
US6312685B1
(en)
|
1998-03-13 |
2001-11-06 |
Timothy C. Fisher |
Red blood cells covalently bound with two different polyethylene glycol derivatives
|
US6942859B2
(en)
|
1998-03-13 |
2005-09-13 |
University Of Southern California |
Red blood cells covalently bound with polymers
|
US6153655A
(en)
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
US6251382B1
(en)
|
1998-04-17 |
2001-06-26 |
Enzon, Inc. |
Biodegradable high molecular weight polymeric linkers and their conjugates
|
PL192364B1
(pl)
*
|
1998-06-08 |
2006-10-31 |
Hoffmann La Roche |
Zastosowanie koniugatu PEG-IFN-α 2A w połączeniu z rybawiryną
|
US6214330B1
(en)
|
1998-07-13 |
2001-04-10 |
Enzon, Inc. |
Coumarin and related aromatic-based polymeric prodrugs
|
EP1100880B1
(en)
|
1998-08-06 |
2010-10-06 |
Duke University |
Urate oxidase
|
ES2404074T3
(es)
|
1998-08-06 |
2013-05-23 |
Mountain View Pharmaceuticals, Inc. |
Conjugados de peg-oxidasa de urato y su uso
|
US6783965B1
(en)
|
2000-02-10 |
2004-08-31 |
Mountain View Pharmaceuticals, Inc. |
Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
|
US20060188971A1
(en)
*
|
1998-08-06 |
2006-08-24 |
Duke University |
Urate oxidase
|
ATE327254T1
(de)
*
|
1998-10-16 |
2006-06-15 |
Biogen Idec Inc |
Interferon-beta fusionsproteine und deren verwendungen
|
IL142282A0
(en)
*
|
1998-10-16 |
2002-03-10 |
Biogen Inc |
Compositions containing polymer conjugates of interferon-beta-1a
|
US6458953B1
(en)
*
|
1998-12-09 |
2002-10-01 |
La Jolla Pharmaceutical Company |
Valency platform molecules comprising carbamate linkages
|
AU768027B2
(en)
*
|
1999-02-24 |
2003-11-27 |
Uab Research Foundation, The |
Taxane derivatives for targeted therapy of cancer
|
AU3501700A
(en)
|
1999-02-26 |
2000-09-14 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
US6852696B2
(en)
|
1999-03-26 |
2005-02-08 |
The University Of Texas System |
Inhibitors of glycosaminoglycans
|
US7169889B1
(en)
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
CZ299516B6
(cs)
*
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
JO2291B1
(en)
|
1999-07-02 |
2005-09-12 |
اف . هوفمان لاروش ايه جي |
Erythropoietin derivatives
|
AU7084300A
(en)
*
|
1999-08-27 |
2001-03-26 |
Cohesion Technologies, Inc. |
Compositions that form interpenetrating polymer networks for use as high strength medical sealants
|
CN1111166C
(zh)
*
|
1999-09-10 |
2003-06-11 |
云南汉德生物技术有限公司 |
水溶性三尖杉磷碱聚氨基酸酯或其盐,含它们的药物组合物及其医药用途
|
US6713454B1
(en)
|
1999-09-13 |
2004-03-30 |
Nobex Corporation |
Prodrugs of etoposide and etoposide analogs
|
US6376470B1
(en)
|
1999-09-23 |
2002-04-23 |
Enzon, Inc. |
Polymer conjugates of ara-C and ara-C derivatives
|
WO2001024763A2
(en)
|
1999-10-01 |
2001-04-12 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
CA2395254C
(en)
*
|
1999-12-24 |
2010-05-11 |
Kyowa Hakko Kogyo Co., Ltd. |
Branched polyalkylene glycols
|
AU782580B2
(en)
|
2000-01-10 |
2005-08-11 |
Maxygen, Inc. |
G-CSF conjugates
|
DK1257295T3
(da)
|
2000-02-11 |
2009-08-10 |
Bayer Healthcare Llc |
Faktor VII eller VIIA-lignende molekyler
|
US6756037B2
(en)
|
2000-03-31 |
2004-06-29 |
Enzon, Inc. |
Polymer conjugates of biologically active agents and extension moieties for facilitating conjugation of biologically active agents to polymeric terminal groups
|
US6777387B2
(en)
|
2000-03-31 |
2004-08-17 |
Enzon Pharmaceuticals, Inc. |
Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
|
ES2270998T3
(es)
*
|
2000-04-04 |
2007-04-16 |
Bioartificial Gel Technologies Inc. |
Procedimiento para la preparacion de hidrogeles a base de proteinas.
|
EP1278544A4
(en)
|
2000-04-12 |
2004-08-18 |
Human Genome Sciences Inc |
ALBUMIN FUSION PROTEINS
|
ES2237574T5
(es)
|
2000-05-15 |
2017-08-09 |
F. Hoffmann-La Roche Ag |
Composición farmacéutica líquida que contiene un derivado de eritropoyetina
|
SG98393A1
(en)
|
2000-05-19 |
2003-09-19 |
Inst Materials Research & Eng |
Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
|
US7259146B2
(en)
|
2000-05-26 |
2007-08-21 |
Ortho-Mcneil Pharmaceutical, Inc. |
Neuroprotective peptides
|
EP1292337A2
(en)
|
2000-06-08 |
2003-03-19 |
La Jolla Pharmaceutical |
Multivalent platform molecules comprising high molecular weight polyethylene oxide
|
WO2001096528A2
(en)
|
2000-06-15 |
2001-12-20 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
WO2002002641A1
(en)
*
|
2000-06-16 |
2002-01-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
AU2002218769A1
(en)
*
|
2000-07-12 |
2002-01-21 |
Gryphon Therapeutics, Inc. |
Chemokine receptor modulators, production and use
|
KR100396983B1
(ko)
*
|
2000-07-29 |
2003-09-02 |
이강춘 |
고반응성의 가지 달린 고분자 유도체 및 고분자와 단백질또는 펩타이드의 접합체
|
WO2002016412A2
(en)
|
2000-08-18 |
2002-02-28 |
Dyax Corp. |
Binding polypeptides for b lymphocyte stimulator protein (blys)
|
US20030091565A1
(en)
*
|
2000-08-18 |
2003-05-15 |
Beltzer James P. |
Binding polypeptides and methods based thereon
|
US7118737B2
(en)
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
JP2004508338A
(ja)
*
|
2000-09-08 |
2004-03-18 |
グリフォン セラピューティクス,インコーポレーテッド |
ポリマー修飾合成タンパク質
|
US7052686B2
(en)
|
2000-09-29 |
2006-05-30 |
Schering Corporation |
Pegylated interleukin-10
|
US20020065397A1
(en)
|
2000-10-12 |
2002-05-30 |
Joseph Roberts |
Protecting therapeutic compositions from host-mediated inactivation
|
JP5170931B2
(ja)
|
2000-10-16 |
2013-03-27 |
中外製薬株式会社 |
Peg修飾エリスロポエチン
|
US20030228309A1
(en)
*
|
2000-11-08 |
2003-12-11 |
Theodora Salcedo |
Antibodies that immunospecifically bind to TRAIL receptors
|
US20060062786A1
(en)
*
|
2000-11-08 |
2006-03-23 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to TRAIL receptors
|
US7053150B2
(en)
|
2000-12-18 |
2006-05-30 |
Nektar Therapeutics Al, Corporation |
Segmented polymers and their conjugates
|
CN1406131A
(zh)
*
|
2000-12-25 |
2003-03-26 |
株式会社资生堂 |
活化交感神经的香料组合物
|
EP1400550B1
(en)
*
|
2001-01-30 |
2010-06-23 |
Kyowa Hakko Kirin Co., Ltd. |
Branched polyalkylene glycols
|
MXPA03006952A
(es)
*
|
2001-02-02 |
2004-10-15 |
Johnson & Johnson |
Tratamiento de disfuncion neurologica que comprende sulfamatos de fructopiranosa y eritropoyetina.
|
DE60223499T2
(de)
*
|
2001-02-20 |
2008-10-16 |
Enzon, Inc. |
Terminal verzweigte, polymere linker und diese enthaltende polymere konjugate
|
WO2002074806A2
(en)
|
2001-02-27 |
2002-09-26 |
Maxygen Aps |
New interferon beta-like molecules
|
JP2004532203A
(ja)
*
|
2001-03-21 |
2004-10-21 |
ザ、ユニバーシティ、オブ、テキサス、システム |
グリコサミノグリカンの阻害剤
|
US20090226429A1
(en)
*
|
2001-05-25 |
2009-09-10 |
Human Genome Sciences, Inc. |
Antibodies That Immunospecifically Bind to TRAIL Receptors
|
US7348003B2
(en)
|
2001-05-25 |
2008-03-25 |
Human Genome Sciences, Inc. |
Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
|
MXPA03010747A
(es)
*
|
2001-05-25 |
2004-03-02 |
Human Genome Sciences Inc |
Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
|
US7361341B2
(en)
*
|
2001-05-25 |
2008-04-22 |
Human Genome Sciences, Inc. |
Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
|
US20050214209A1
(en)
*
|
2001-05-25 |
2005-09-29 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to TRAIL receptors
|
US6828305B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828297B2
(en)
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6835802B2
(en)
*
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
US7713932B2
(en)
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
US6713452B2
(en)
|
2001-06-04 |
2004-03-30 |
Nobex Corporation |
Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6858580B2
(en)
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US20040077835A1
(en)
*
|
2001-07-12 |
2004-04-22 |
Robin Offord |
Chemokine receptor modulators, production and use
|
ATE376020T1
(de)
*
|
2001-08-22 |
2007-11-15 |
Bioartificial Gel Technologies Inc |
Verfahren zu herstellung von aktivierten polyethylenglykolen
|
GB0121709D0
(en)
*
|
2001-09-07 |
2001-10-31 |
Imp College Innovations Ltd |
Food inhibition agent
|
CN100350968C
(zh)
|
2001-09-24 |
2007-11-28 |
皇家创新有限公司 |
饮食行为的改进
|
US7157277B2
(en)
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7795210B2
(en)
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US8008252B2
(en)
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US6818613B2
(en)
|
2001-11-07 |
2004-11-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aqueous sustained-release formulations of proteins
|
MXPA04004336A
(es)
*
|
2001-11-07 |
2005-05-16 |
Nektar Therapeutics Al Corp |
Polimeros ramificados y sus conjugados.
|
US20030171285A1
(en)
*
|
2001-11-20 |
2003-09-11 |
Finn Rory F. |
Chemically-modified human growth hormone conjugates
|
WO2003045423A1
(en)
*
|
2001-11-28 |
2003-06-05 |
Ortho-Mcneil Pharmaceutical, Inc. |
Erythropoietin dosing regimen for treating anemia
|
CN1610696A
(zh)
*
|
2001-12-20 |
2005-04-27 |
人体基因组科学有限公司 |
免疫特异性结合trail受体的抗体
|
EP2277910A1
(en)
|
2001-12-21 |
2011-01-26 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US8058233B2
(en)
*
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
WO2003057235A2
(en)
|
2002-01-10 |
2003-07-17 |
Imperial College Innovations Ltd |
Modification of feeding behavior
|
US7144978B2
(en)
|
2002-01-15 |
2006-12-05 |
Pan Asia Bio Co., Ltd. |
Multidrop tree branching functional polyethylene glycol, methods of preparing and using same
|
US7129267B2
(en)
*
|
2002-03-11 |
2006-10-31 |
Janssen Pharmaceutica N.V. |
Methods for SHP1 mediated neuroprotection
|
DE60315145T2
(de)
*
|
2002-03-13 |
2008-04-30 |
Beijing Jiankai Technology Co., Ltd. |
Hydrophiles polymerderivat mit y-verzweigung und herstellungsverfahren dafür; obige verbindung enthaltender medizinischer verbundwerkstoff
|
AU2003210052A1
(en)
*
|
2002-03-20 |
2003-09-29 |
Biopolymed Inc. |
Preparation of g-csf stoichiometrically conjugated with biocompatible polymers at cystein residue
|
EP1497445A2
(en)
*
|
2002-04-01 |
2005-01-19 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to gmad
|
ITMI20020951A1
(it)
*
|
2002-05-06 |
2003-11-06 |
Univ Degli Studi Trieste |
Derivati multifunzionali del polietilenglicole loro preparazione ed impiego
|
EP1534753B1
(en)
*
|
2002-05-28 |
2011-08-03 |
UCB Pharma, S.A. |
Peg positional isomer of an anti-tnfalpha antibody (cdp870)
|
MXPA04012496A
(es)
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
DK1517710T3
(da)
|
2002-06-21 |
2011-07-18 |
Novo Nordisk Healthcare Ag |
Pegylerede faktor VII-glycoformer
|
AU2003256381A1
(en)
*
|
2002-07-03 |
2004-01-23 |
Pericor Science, Inc |
Compositions of hyaluronic acid and methods of use
|
US7297348B2
(en)
|
2002-07-19 |
2007-11-20 |
Omeros Corporation |
Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from
|
US7122189B2
(en)
|
2002-08-13 |
2006-10-17 |
Enzon, Inc. |
Releasable polymeric conjugates based on aliphatic biodegradable linkers
|
US7087229B2
(en)
*
|
2003-05-30 |
2006-08-08 |
Enzon Pharmaceuticals, Inc. |
Releasable polymeric conjugates based on aliphatic biodegradable linkers
|
US7413738B2
(en)
*
|
2002-08-13 |
2008-08-19 |
Enzon Pharmaceuticals, Inc. |
Releasable polymeric conjugates based on biodegradable linkers
|
US20040091490A1
(en)
*
|
2002-08-28 |
2004-05-13 |
Robert Johnson |
Stable pH optimized formulation of a modified antibody
|
WO2004019860A2
(en)
*
|
2002-08-28 |
2004-03-11 |
Pharmacia Corporation |
Formulations of modified antibodies and methods of making the same
|
US7459435B2
(en)
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
TWI281864B
(en)
*
|
2002-11-20 |
2007-06-01 |
Pharmacia Corp |
N-terminally monopegylated human growth hormone conjugates and process for their preparation
|
US7459436B2
(en)
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
RS20050502A
(en)
*
|
2002-12-26 |
2007-08-03 |
Mountain View Pharmaceuticals Inc., |
Polymer conjugates of interferon- beta with enhanced biological potency
|
EP1628618A4
(en)
*
|
2002-12-26 |
2009-09-09 |
Mountain View Pharmaceuticals |
POLYMER CONJUGATES OF CYTOKINES, CHEMOKINS, GROWTH FACTORS, POLYPEPTIDE HORMONES AND ANTAGONISTS THEREOF WITH PRESERVED RECEPTOR BINDING ACTIVITY
|
WO2004061094A1
(en)
|
2002-12-30 |
2004-07-22 |
Gryphon Therapeutics, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
US20040219214A1
(en)
*
|
2002-12-30 |
2004-11-04 |
Angiotech International Ag |
Tissue reactive compounds and compositions and uses thereof
|
ATE457716T1
(de)
|
2002-12-30 |
2010-03-15 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
GB0300571D0
(en)
*
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
ES2335005T5
(es)
*
|
2003-03-05 |
2013-04-17 |
Halozyme, Inc. |
Glicoproteína hialuronidasa soluble (shasegp), proceso para prepararla, usos y composiciones farmacéuticas que la comprenden
|
US20090123367A1
(en)
*
|
2003-03-05 |
2009-05-14 |
Delfmems |
Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
|
US7871607B2
(en)
*
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
US20060104968A1
(en)
*
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
BRPI0408358A
(pt)
|
2003-03-14 |
2006-03-21 |
Neose Technologies Inc |
polìmeros hidrossolúveis ramificados e seus conjugados
|
MXPA05010773A
(es)
|
2003-04-09 |
2005-12-12 |
Neose Technologies Inc |
Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
ES2340494T3
(es)
|
2003-04-15 |
2010-06-04 |
Glaxosmithkline Llc |
Mutantes de sustitucion de il-18 humana y sus conjugados.
|
BRPI0410164A
(pt)
*
|
2003-05-09 |
2006-05-16 |
Neose Technologies Inc |
composições e métodos para preparação de mutantes de glicosilação de hormÈnio do crescimento humano
|
US20070172446A1
(en)
|
2003-05-16 |
2007-07-26 |
Intermune, Inc. |
Synthetic chemokine receptor ligands and methods of use thereof
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
PT2644206T
(pt)
*
|
2003-05-23 |
2019-07-10 |
Nektar Therapeutics |
Derivados de peg contendo duas cadeias de peg
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
DE602004032553D1
(de)
*
|
2003-09-05 |
2011-06-16 |
Gen Hospital Corp |
Polyacetal-arzneimittelkonjugate als freisetzungssystem
|
EP1525890A1
(en)
*
|
2003-10-02 |
2005-04-27 |
Complex Biosystems GmbH |
Protein-Proteophore complexes
|
EP2322569B1
(en)
|
2003-10-09 |
2020-08-26 |
Ambrx, Inc. |
Polymer derivatives for the selective modification of proteins
|
EP1673387B1
(en)
|
2003-10-10 |
2010-09-15 |
Novo Nordisk A/S |
Il-21 derivatives
|
AP2287A
(en)
|
2003-10-14 |
2011-10-31 |
Intermune Inc |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication.
|
EP2641611A3
(en)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Combination therapy
|
WO2005040758A2
(en)
*
|
2003-10-24 |
2005-05-06 |
Intermune, Inc. |
Use of pirfenidone in therapeutic regimens
|
EP1694347B1
(en)
*
|
2003-11-24 |
2013-11-20 |
BioGeneriX AG |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US7842661B2
(en)
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US7956032B2
(en)
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
EP1694351A2
(en)
*
|
2003-12-03 |
2006-08-30 |
Neose Technologies, Inc. |
Glycopegylated follicle stimulating hormone
|
US20060182692A1
(en)
*
|
2003-12-16 |
2006-08-17 |
Fishburn C S |
Chemically modified small molecules
|
US7786133B2
(en)
*
|
2003-12-16 |
2010-08-31 |
Nektar Therapeutics |
Chemically modified small molecules
|
JP2007514673A
(ja)
|
2003-12-19 |
2007-06-07 |
エフ.ホフマン−ラ ロシュ アーゲー |
慢性炎症性腸疾患の際の鉄分布障害の処置におけるエリスロポエチンの使用
|
CN101072789B
(zh)
|
2004-01-08 |
2013-05-15 |
生物种属学股份公司 |
肽的o-连接的糖基化
|
CA2553040A1
(en)
|
2004-02-02 |
2005-08-18 |
Ambrx, Inc. |
Modified human four helical bundle polypeptides and their uses
|
PL1729795T3
(pl)
|
2004-02-09 |
2016-08-31 |
Human Genome Sciences Inc |
Białka fuzyjne albuminy
|
US6887952B1
(en)
|
2004-02-12 |
2005-05-03 |
Biosite, Inc. |
N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use
|
US7351787B2
(en)
|
2004-03-05 |
2008-04-01 |
Bioartificial Gel Technologies, Inc. |
Process for the preparation of activated polyethylene glycols
|
US20050238628A1
(en)
*
|
2004-04-08 |
2005-10-27 |
Blau Carl A |
Methods for treating cancer
|
KR100974733B1
(ko)
|
2004-04-28 |
2010-08-06 |
안지오디바이스 인터내셔널 게엠베하 |
가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
|
US8562965B2
(en)
|
2004-05-03 |
2013-10-22 |
Nektar Therapeutics |
Polymer derivatives comprising an acetal or ketal branching point
|
CN102603895B
(zh)
*
|
2004-06-18 |
2016-09-28 |
Ambrx公司 |
新颖抗原结合多肽和其用途
|
US20080300173A1
(en)
|
2004-07-13 |
2008-12-04 |
Defrees Shawn |
Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
|
UA103758C2
(ru)
|
2004-07-19 |
2013-11-25 |
Биокон Лимитед |
Конъюгаты олигомеров инсулина, их композиции и применение
|
BRPI0512396A
(pt)
*
|
2004-07-21 |
2008-03-11 |
Ambrx Inc |
polipeptìdeos biossintéticos utilizando aminoácidos codificados não naturalmente
|
US20090292110A1
(en)
*
|
2004-07-23 |
2009-11-26 |
Defrees Shawn |
Enzymatic modification of glycopeptides
|
US7772182B2
(en)
*
|
2004-08-05 |
2010-08-10 |
Alza Corporation |
Stable suspension formulations of erythropoietin receptor agonists
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
JP2008513356A
(ja)
*
|
2004-08-09 |
2008-05-01 |
アリオス バイオファーマ インク. |
合成高度糖鎖付加プロテアーゼ耐性ポリペプチド変異体、それを使用する経口製剤および方法
|
CA2579370A1
(en)
*
|
2004-09-09 |
2006-03-23 |
Biosite Incorporated |
Methods and compositions for measuring canine bnp and uses thereof
|
WO2006031811A2
(en)
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
US8303973B2
(en)
|
2004-09-17 |
2012-11-06 |
Angiotech Pharmaceuticals (Us), Inc. |
Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
|
US8790632B2
(en)
*
|
2004-10-07 |
2014-07-29 |
Actamax Surgical Materials, Llc |
Polymer-based tissue-adhesive form medical use
|
EP1796746B1
(en)
|
2004-10-07 |
2011-05-04 |
E.I. Du Pont De Nemours And Company |
Polysaccharide-based polymer tissue adhesive for medical use
|
JP5948627B2
(ja)
|
2004-10-29 |
2016-07-20 |
レイショファーム ゲーエムベーハー |
線維芽細胞成長因子(fgf)のリモデリングと糖質ペグ化
|
WO2006073846A2
(en)
|
2004-12-22 |
2006-07-13 |
Ambrx, Inc. |
Methods for expression and purification of recombinant human growth hormone
|
NZ555386A
(en)
|
2004-12-22 |
2011-01-28 |
Ambrx Inc |
Formulations of human growth hormone comprising a non-naturally encoded amino acid
|
KR20070090023A
(ko)
|
2004-12-22 |
2007-09-04 |
암브룩스, 인코포레이티드 |
변형 인간 성장 호르몬
|
US7385028B2
(en)
|
2004-12-22 |
2008-06-10 |
Ambrx, Inc |
Derivatization of non-natural amino acids and polypeptides
|
KR101252835B1
(ko)
*
|
2004-12-22 |
2013-04-10 |
암브룩스, 인코포레이티드 |
아미노아실-tRNA 합성효소의 조성물 및 그것의 용도
|
EP1858543B1
(en)
|
2005-01-10 |
2013-11-27 |
BioGeneriX AG |
Glycopegylated granulocyte colony stimulating factor
|
US7879979B2
(en)
*
|
2005-01-21 |
2011-02-01 |
Alere International |
Arginine analogs, and methods for their synthesis and use
|
US7365127B2
(en)
*
|
2005-02-04 |
2008-04-29 |
Enzon Pharmaceuticals, Inc. |
Process for the preparation of polymer conjugates
|
US20080268013A1
(en)
*
|
2005-02-10 |
2008-10-30 |
Emory University |
Polyethylene Oxide Polymers Including Anti-Inflammatory Glycodendrons
|
WO2006088248A1
(ja)
|
2005-02-18 |
2006-08-24 |
Nof Corporation |
ポリオキシアルキレン誘導体
|
JPWO2006088245A1
(ja)
*
|
2005-02-18 |
2008-07-10 |
国立大学法人徳島大学 |
ポリオキシアルキレン鎖含有脂質誘導体及び該誘導体を含有する脂質膜構造体
|
JP2008534640A
(ja)
|
2005-04-05 |
2008-08-28 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
タンパク質の機能部位またはエピトープの遮蔽方法
|
EP2386571B1
(en)
|
2005-04-08 |
2016-06-01 |
ratiopharm GmbH |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
US20080159976A1
(en)
*
|
2005-04-11 |
2008-07-03 |
Jacob Hartman |
Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
|
US8148123B2
(en)
*
|
2005-04-11 |
2012-04-03 |
Savient Pharmaceuticals, Inc. |
Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
|
MX2007012548A
(es)
*
|
2005-04-11 |
2008-03-11 |
Savient Pharmaceuticals Inc |
Formas variantes de urato oxidasa y uso de las mismas.
|
PL3321359T3
(pl)
|
2005-04-11 |
2021-06-28 |
Horizon Pharma Rheumatology Llc |
Wariantowe postacie oksydazy moczanowej i ich zastosowanie
|
US8273339B2
(en)
|
2005-04-12 |
2012-09-25 |
Nektar Therapeutics |
Polymer-based compositions and conjugates of antimicrobial agents
|
US7833979B2
(en)
*
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
EP1883425A1
(en)
*
|
2005-05-23 |
2008-02-06 |
Universite De Geneve |
Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
|
EP2975135A1
(en)
*
|
2005-05-25 |
2016-01-20 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
CN101247821B
(zh)
*
|
2005-06-03 |
2013-01-23 |
Ambrx公司 |
经改良人类干扰素分子和其用途
|
GB0511986D0
(en)
*
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
EP1893632B1
(en)
|
2005-06-17 |
2015-08-12 |
Novo Nordisk Health Care AG |
Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine
|
EP1926768B1
(en)
|
2005-07-18 |
2011-09-14 |
Nektar Therapeutics |
Branched functionalized polymers using branched polyol cores
|
KR100735784B1
(ko)
*
|
2005-07-20 |
2007-07-06 |
재단법인 목암생명공학연구소 |
인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
KR101285904B1
(ko)
|
2005-08-18 |
2013-07-15 |
암브룩스, 인코포레이티드 |
tRNA 조성물 및 이의 용도
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
US8679536B2
(en)
*
|
2005-08-24 |
2014-03-25 |
Actamax Surgical Materials, Llc |
Aldol-crosslinked polymeric hydrogel adhesives
|
US8679537B2
(en)
*
|
2005-08-24 |
2014-03-25 |
Actamaz Surgical Materials, LLC |
Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive
|
US7601798B2
(en)
*
|
2005-10-04 |
2009-10-13 |
Enzon Pharmaceuticals, Inc. |
Methods of preparing polymers having terminal amine groups using protected amine salts
|
EA015860B1
(ru)
*
|
2005-10-13 |
2011-12-30 |
Хьюман Дженом Сайенсиз, Инк. |
Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
|
US9168286B2
(en)
*
|
2005-10-13 |
2015-10-27 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of patients with autoantibody positive disease
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
PL1954710T3
(pl)
*
|
2005-11-08 |
2011-09-30 |
Ambrx Inc |
Przyspieszacze do modyfikacji aminokwasów niewystępujących w przyrodzie i polipeptydów zbudowanych z aminokwasów nie występujących w przyrodzie
|
KR20080079643A
(ko)
*
|
2005-11-16 |
2008-09-01 |
암브룩스, 인코포레이티드 |
비-천연 아미노산을 포함하는 방법 및 조성물
|
US20080317670A1
(en)
*
|
2005-12-14 |
2008-12-25 |
Ambrx, Inc. |
Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides
|
US7989554B2
(en)
|
2006-01-10 |
2011-08-02 |
Enzon Pharmaceuticals, Inc. |
Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid
|
US20150038413A1
(en)
|
2006-02-03 |
2015-02-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US9249407B2
(en)
|
2006-02-03 |
2016-02-02 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8048849B2
(en)
|
2006-02-03 |
2011-11-01 |
Modigene, Inc. |
Long-acting polypeptides and methods of producing same
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US20140113860A1
(en)
|
2006-02-03 |
2014-04-24 |
Prolor Biotech Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US10221228B2
(en)
|
2006-02-03 |
2019-03-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US10351615B2
(en)
|
2006-02-03 |
2019-07-16 |
Opko Biologics Ltd. |
Methods of treatment with long-acting growth hormone
|
LT1988910T
(lt)
*
|
2006-02-28 |
2018-01-10 |
Kodiak Sciences Inc. |
Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdas
|
KR101201055B1
(ko)
|
2006-03-13 |
2012-11-15 |
리아트 민쯔 |
악액질 및/또는 식욕감퇴 및/또는 식욕감퇴-악액질 및/또는영양장애 및/또는 지방이영양증 및/또는 근육 쇠약 및/또는 식욕-자극의 치료를 위한 그렐린 스플라이스 변이체의 용도
|
WO2007123765A2
(en)
|
2006-03-31 |
2007-11-01 |
Human Genome Sciences Inc. |
Neutrokine-alpha and neutrokine-alpha splice variant
|
HU230758B1
(hu)
*
|
2006-04-12 |
2018-03-28 |
Crealta Pharmaceuticals LLC 100% |
Fehérjék tisztítása kationos felületaktív anyaggal
|
CN101062407A
(zh)
|
2006-04-29 |
2007-10-31 |
中国科学院上海生命科学研究院 |
促红细胞生成素在预防或治疗视网膜损伤中的用途
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
EP2581450B1
(en)
|
2006-05-02 |
2018-08-15 |
MedImmune Limited |
Non-natural amino acid substituted polypeptides
|
JP2009537609A
(ja)
|
2006-05-24 |
2009-10-29 |
ノボ ノルディスク ヘルス ケア アーゲー |
延長されたfixアナログ及び誘導体
|
WO2007146835A2
(en)
*
|
2006-06-09 |
2007-12-21 |
Enzon Pharmaceuticals, Inc. |
Indenoisoquinoline-releasable polymer conjugates
|
US7807436B2
(en)
*
|
2006-06-30 |
2010-10-05 |
Defiante Farmaceutica, S.A. |
Recombinant host for producing L-asparaginase II
|
US9187532B2
(en)
|
2006-07-21 |
2015-11-17 |
Novo Nordisk A/S |
Glycosylation of peptides via O-linked glycosylation sequences
|
EP2054437A2
(en)
*
|
2006-08-07 |
2009-05-06 |
Teva Biopharmaceuticals USA, Inc. |
Albumin-insulin fusion proteins
|
PT2064333E
(pt)
*
|
2006-09-08 |
2014-06-09 |
Ambrx Inc |
Supressor híbrido arnt para células de vertebrados
|
KR20090051227A
(ko)
*
|
2006-09-08 |
2009-05-21 |
암브룩스, 인코포레이티드 |
척추동물 세포를 위한 하이브리드 서프레서 tRNA
|
EP2069396B1
(en)
|
2006-09-08 |
2015-10-21 |
Ambrx, Inc. |
Modified human plasma polypeptide or fc scaffolds and their uses
|
US8110559B2
(en)
*
|
2006-09-15 |
2012-02-07 |
Enzon Pharmaceuticals, Inc. |
Hindered ester-based biodegradable linkers for oligonucleotide delivery
|
US8367065B2
(en)
*
|
2006-09-15 |
2013-02-05 |
Enzon Pharmaceuticals, Inc. |
Targeted polymeric prodrugs containing multifunctional linkers
|
RU2009114154A
(ru)
*
|
2006-09-15 |
2010-10-20 |
Энзон Фармасьютикалз, Инк. (Us) |
Полимерные пролекарства с направленной доставкой, содержащие полифункциональные линкеры
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
US20080081031A1
(en)
|
2006-09-28 |
2008-04-03 |
Schering Corporation |
Use of Pegylated IL-10 to Treat Cancer
|
JP2010505874A
(ja)
*
|
2006-10-03 |
2010-02-25 |
ノヴォ ノルディスク アー/エス |
ポリペプチドコンジュゲートの精製方法
|
CN101600448B
(zh)
|
2006-10-04 |
2015-11-25 |
诺和诺德公司 |
甘油连接的peg化的糖和糖肽
|
WO2008051383A2
(en)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Use of alcohol co-solvents to improve pegylation reaction yields
|
CN101168594B
(zh)
*
|
2006-10-24 |
2011-07-27 |
北京键凯科技有限公司 |
寡肽为骨架的聚乙二醇活性衍生物、其制备方法及与药物分子的结合物
|
US8043829B2
(en)
*
|
2006-10-25 |
2011-10-25 |
Amgen Inc. |
DNA encoding chimeric toxin peptide fusion proteins and vectors and mammalian cells for recombinant expression
|
CN101541857B
(zh)
*
|
2006-11-27 |
2012-12-12 |
阿克塔马克斯手术器材有限责任公司 |
多官能聚环氧烷、水凝胶和组织粘合剂
|
TWI428346B
(zh)
*
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
WO2008079677A2
(en)
*
|
2006-12-20 |
2008-07-03 |
Arkema Inc. |
Polymer encapsulation and/or binding
|
WO2008083302A2
(en)
*
|
2006-12-29 |
2008-07-10 |
Enzon Pharmaceuticals, Inc. |
Use of adenosine deaminase for treating pulmonary disease
|
JP2010515762A
(ja)
*
|
2007-01-16 |
2010-05-13 |
エンゾン ファーマスーティカルズ インコーポレイテッド |
ポサコナゾール−ポリマー複合体、並びに、ポサコナゾールおよびそのポリマー複合体を使用した治療方法
|
AU2008210290B2
(en)
*
|
2007-02-01 |
2013-10-31 |
National Research Council Of Canada |
Formulations of lipophilic bioactive molecules
|
CN104163864B
(zh)
*
|
2007-03-30 |
2017-08-01 |
Ambrx公司 |
经修饰fgf‑21多肽和其用途
|
KR20150064246A
(ko)
|
2007-04-03 |
2015-06-10 |
바이오제너릭스 게엠베하 |
글리코페길화 g―csf를 이용하는 치료 방법
|
TWI412591B
(zh)
|
2007-04-20 |
2013-10-21 |
Sigma Tau Rare Diseases S A |
穩定的重組腺苷脫胺酶
|
US8741283B2
(en)
*
|
2007-04-20 |
2014-06-03 |
Sigma-Tau Rare Diseases, S.A. |
Adenosine deaminase anticancer therapy
|
AU2008247815B2
(en)
|
2007-05-02 |
2012-09-06 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
AU2008262490B2
(en)
*
|
2007-05-22 |
2011-11-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
CA2690611C
(en)
|
2007-06-12 |
2015-12-08 |
Novo Nordisk A/S |
Improved process for the production of nucleotide sugars
|
JP2010533202A
(ja)
*
|
2007-07-11 |
2010-10-21 |
エンゾン ファーマシューティカルズ,インコーポレーテッド |
多置換芳香族部分を含むポリマー性薬剤送達システム
|
CL2008002399A1
(es)
*
|
2007-08-16 |
2009-01-02 |
Pharmaessentia Corp |
Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c.
|
CA2707840A1
(en)
*
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
US8088884B2
(en)
*
|
2007-09-27 |
2012-01-03 |
Serina Therapeutics, Inc. |
Multi-armed forms of activated polyoxazoline and methods of synthesis thereof
|
BRPI0818004B8
(pt)
|
2007-10-16 |
2021-05-25 |
Biocon Ltd |
composição farmacêutica sólida administrável por via oral e o processo da mesma.
|
US8846095B2
(en)
*
|
2007-11-14 |
2014-09-30 |
Actamax Surgical Materials, Llc |
Dextran-based polymer tissue adhesive for medical use
|
US8426492B2
(en)
*
|
2007-11-14 |
2013-04-23 |
Actamax Surgical Materials, Llc |
Oxidized cationic polysaccharide-based polymer tissue adhesive for medical use
|
MX338336B
(es)
*
|
2007-11-20 |
2016-04-07 |
Ambrx Inc |
Polipeptidos de insulina modificados y sus usos.
|
US8101706B2
(en)
|
2008-01-11 |
2012-01-24 |
Serina Therapeutics, Inc. |
Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same
|
WO2009089542A2
(en)
|
2008-01-11 |
2009-07-16 |
Serina Therapeutics, Inc. |
Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same
|
CN101939443B
(zh)
|
2008-02-08 |
2014-01-29 |
Ambrx公司 |
经修饰瘦素多肽和其用途
|
WO2009108806A1
(en)
|
2008-02-27 |
2009-09-03 |
Novo Nordisk A/S |
Conjugated factor viii molecules
|
TWI395593B
(zh)
|
2008-03-06 |
2013-05-11 |
Halozyme Inc |
可活化的基質降解酵素之活體內暫時性控制
|
EP2260102A1
(en)
|
2008-03-25 |
2010-12-15 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Treating cancer by down-regulating frizzled-4 and/or frizzled-1
|
CA2721229C
(en)
|
2008-04-14 |
2022-08-23 |
Halozyme, Inc. |
Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
|
BRPI0911249A2
(pt)
|
2008-04-16 |
2017-05-23 |
Biogen Idec Inc |
método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição
|
TWI394580B
(zh)
|
2008-04-28 |
2013-05-01 |
Halozyme Inc |
超快起作用胰島素組成物
|
US8932622B2
(en)
*
|
2008-06-03 |
2015-01-13 |
Actamax Surgical Materials, Llc |
Tissue coating for preventing undesired tissue-to-tissue adhesions
|
KR20110033922A
(ko)
|
2008-07-08 |
2011-04-01 |
더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 |
전사의 신호 변환자 및 활성제(stats)의 증식 및 활성화의 신규한 억제제
|
US20100015231A1
(en)
*
|
2008-07-17 |
2010-01-21 |
E.I. Du Pont De Nemours And Company |
Low swell, long-lived hydrogel sealant
|
US8551136B2
(en)
|
2008-07-17 |
2013-10-08 |
Actamax Surgical Materials, Llc |
High swell, long-lived hydrogel sealant
|
PT2318029T
(pt)
*
|
2008-07-23 |
2018-01-10 |
Ambrx Inc |
Polipéptidos de g-csf bovino modificados e suas utilizações
|
AR072850A1
(es)
*
|
2008-07-31 |
2010-09-22 |
Pharmaessentia Corp |
Conjugados peptido-polimero
|
EP2334320B1
(en)
*
|
2008-08-25 |
2016-02-10 |
Viromed Co., Ltd. |
Biopolymer conjugates comprising an interleukin-11 analog
|
EP2342223B1
(en)
|
2008-09-26 |
2017-04-26 |
Ambrx, Inc. |
Modified animal erythropoietin polypeptides and their uses
|
ES2660000T3
(es)
*
|
2008-09-26 |
2018-03-20 |
Ambrx, Inc. |
Vacunas y microorganismos dependientes de la replicación de aminoácidos no naturales
|
US8642280B2
(en)
|
2008-11-07 |
2014-02-04 |
Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Teneurin and cancer
|
US8466327B2
(en)
|
2008-11-19 |
2013-06-18 |
Actamax Surgical Materials, Llc |
Aldehyde-functionalized polyethers and method of making same
|
EP2349357B1
(en)
*
|
2008-11-19 |
2012-10-03 |
Actamax Surgical Materials LLC |
Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之egfr/igfir結合分子
|
EA022752B1
(ru)
|
2008-12-09 |
2016-02-29 |
Галозим, Инк. |
Длинные растворимые полипептиды рн20 и их использование
|
KR20110102420A
(ko)
|
2008-12-10 |
2011-09-16 |
메르사나 테라퓨틱스, 인코포레이티드 |
생분해성 및 생체적합성 캄토테신-중합체 접합체의 약학 제제
|
DK2379115T3
(da)
|
2008-12-17 |
2018-01-29 |
Merck Sharp & Dohme |
Fremstilling og anvendelse af mono- og di-PEG-IL-10
|
US20100160960A1
(en)
*
|
2008-12-19 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Hydrogel tissue adhesive having increased degradation time
|
EP2396035A4
(en)
*
|
2009-02-12 |
2012-09-12 |
Human Genome Sciences Inc |
USE OF ANTAGONISTS OF PROTEIN STIMULATING LYMPHOCYTES B TO PROMOTE GRAFT TOLERANCE
|
WO2010100247A1
(en)
|
2009-03-06 |
2010-09-10 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research |
Novel therapy for anxiety
|
US8765171B2
(en)
*
|
2009-03-09 |
2014-07-01 |
The Regents Of The University Of California |
Methods and compositions for liposomal formulation of antigens and uses thereof
|
US8580732B2
(en)
*
|
2009-04-07 |
2013-11-12 |
Duke University |
Peptide therapy for hyperglycemia
|
WO2010118284A1
(en)
|
2009-04-09 |
2010-10-14 |
E. I. Du Pont De Nemours And Company |
Hydrogel tissue adhesive having reduced degradation time
|
EP2241323A1
(en)
|
2009-04-14 |
2010-10-20 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Tenascin-W and brain cancers
|
US20100330033A1
(en)
*
|
2009-04-16 |
2010-12-30 |
Nian Wu |
Protein-carrier conjugates
|
PL3266463T3
(pl)
|
2009-06-09 |
2024-03-18 |
Prolong Pharmaceuticals, LLC |
Kompozycje hemoglobiny
|
EP2261662B1
(en)
*
|
2009-06-10 |
2014-01-22 |
Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften |
Novel synthetic blocking reagents
|
EP3482768A1
(en)
|
2009-06-25 |
2019-05-15 |
Horizon Pharma Rheumatology LLC |
Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
|
US8796242B2
(en)
|
2009-07-02 |
2014-08-05 |
Actamax Surgical Materials, Llc |
Hydrogel tissue adhesive for medical use
|
JP5872463B2
(ja)
|
2009-07-02 |
2016-03-01 |
アクタマックス サージカル マテリアルズ リミテッド ライアビリティカンパニー |
医療用ヒドロゲル組織接着剤
|
WO2011002956A1
(en)
|
2009-07-02 |
2011-01-06 |
E. I. Du Pont De Nemours And Company |
Aldehyde-functionalized polysaccharides
|
US8580950B2
(en)
|
2009-07-02 |
2013-11-12 |
Actamax Surgical Materials, Llc |
Aldehyde-functionalized polysaccharides
|
US9663778B2
(en)
|
2009-07-09 |
2017-05-30 |
OPKO Biologies Ltd. |
Long-acting coagulation factors and methods of producing same
|
WO2011028229A1
(en)
|
2009-08-24 |
2011-03-10 |
Amunix Operating Inc. |
Coagulation factor ix compositions and methods of making and using same
|
EP2292266A1
(en)
|
2009-08-27 |
2011-03-09 |
Novartis Forschungsstiftung, Zweigniederlassung |
Treating cancer by modulating copine III
|
BR112012008341A2
(pt)
|
2009-09-15 |
2020-08-25 |
Kaneka Corporation |
eritropoietina modificada à qual molécula de cadeia longa solúvel em água é adicionada
|
JP5734985B2
(ja)
|
2009-09-17 |
2015-06-17 |
バクスター・ヘルスケヤー・ソシエテ・アノニムBaxter Healthcare SA |
ヒアルロニダーゼおよび免疫グロブリンの安定な共製剤およびそれらの使用方法
|
US20120244170A1
(en)
|
2009-09-22 |
2012-09-27 |
Rafal Ciosk |
Treating cancer by modulating mex-3
|
WO2011045352A2
(en)
|
2009-10-15 |
2011-04-21 |
Novartis Forschungsstiftung |
Spleen tyrosine kinase and brain cancers
|
US20120213801A1
(en)
|
2009-10-30 |
2012-08-23 |
Ekaterina Gresko |
Phosphorylated Twist1 and cancer
|
US9556272B2
(en)
|
2009-11-11 |
2017-01-31 |
The Trustees Of The University Of Pennsylvania |
Anti-TEM1 antibodies and uses thereof
|
US8765432B2
(en)
|
2009-12-18 |
2014-07-01 |
Oligasis, Llc |
Targeted drug phosphorylcholine polymer conjugates
|
SG181769A1
(en)
|
2009-12-21 |
2012-07-30 |
Ambrx Inc |
Modified porcine somatotropin polypeptides and their uses
|
US20120283171A1
(en)
|
2009-12-21 |
2012-11-08 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
WO2011107591A1
(en)
|
2010-03-05 |
2011-09-09 |
Rigshospitalet |
Chimeric inhibitor molecules of complement activation
|
WO2011107586A1
(en)
|
2010-03-05 |
2011-09-09 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research, |
Smoc1, tenascin-c and brain cancers
|
WO2011131611A1
(en)
|
2010-04-19 |
2011-10-27 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Modulating xrn1
|
SG184860A1
(en)
|
2010-04-27 |
2012-11-29 |
Agency Science Tech & Res |
Eif4e binding peptides
|
GB201007356D0
(en)
|
2010-04-30 |
2010-06-16 |
Leverton Licence Holdings Ltd |
Conjugated factor VIIa
|
US8828181B2
(en)
|
2010-04-30 |
2014-09-09 |
E I Du Pont De Nemours And Company |
Temperature switchable adhesives comprising a crystallizable oil
|
JP2013528374A
(ja)
|
2010-05-10 |
2013-07-11 |
パーシード セラピューティクス リミテッド ライアビリティ カンパニー |
Vla4のポリペプチド阻害剤
|
US20130089538A1
(en)
|
2010-06-10 |
2013-04-11 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute forBiomedical Researh |
Treating cancer by modulating mammalian sterile 20-like kinase 3
|
JP5825507B2
(ja)
*
|
2010-06-25 |
2015-12-02 |
日油株式会社 |
分岐型ヘテロポリエチレングリコール
|
US10040761B2
(en)
|
2010-06-25 |
2018-08-07 |
Nof Corporation |
Branched hetero polyethylene glycol and intermediate
|
DK2595624T3
(da)
|
2010-07-20 |
2018-03-26 |
Halozyme Inc |
Fremgangsmåder til behandling eller forebyggelse af negative bivirkninger forbundet med administration af et anti-hyaluronanmiddel
|
US8409703B2
(en)
|
2010-07-23 |
2013-04-02 |
E I Du Pont De Nemours And Company |
Temperature switchable adhesive assemblies with temperature non-switchable tack
|
PL2605789T3
(pl)
|
2010-08-17 |
2019-11-29 |
Ambrx Inc |
Zmodyfikowane polipeptydy relaksyny i ich zastosowania
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
US20130171159A1
(en)
|
2010-09-10 |
2013-07-04 |
Brian Arthur Hemmings |
Phosphorylated twist1 and metastasis
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
WO2012065937A1
(en)
|
2010-11-15 |
2012-05-24 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research |
Anti-fungal agents
|
EP3434691A1
(en)
|
2010-12-01 |
2019-01-30 |
AlderBio Holdings LLC |
Anti-ngf compositions and use thereof
|
JP2014510045A
(ja)
|
2011-02-08 |
2014-04-24 |
ハロザイム インコーポレイテッド |
ヒアルロナン分解酵素の組成物および脂質製剤ならびに良性前立腺肥大症の治療のためのその使用
|
US20130337537A1
(en)
|
2011-03-02 |
2013-12-19 |
Novo Nordisk A/S |
Coagulation factor-targeting to tlt-1 on activated platelets
|
CA2830065A1
(en)
|
2011-03-16 |
2012-09-20 |
Amgen Inc. |
Potent and selective inhibitors of nav1.3 and nav1.7
|
DK2709663T3
(da)
|
2011-05-20 |
2019-05-20 |
Alderbio Holdings Llc |
Anvendelse af anti-CGRP-antistoffer og antistoffragmenter til forebyggelse eller inhibering af fotofobi eller aversion mod lys hos individer med behov herfor, især migrænikere
|
NZ717704A
(en)
|
2011-05-20 |
2022-08-26 |
H Lundbeck As |
Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea
|
RS61793B1
(sr)
|
2011-05-20 |
2021-06-30 |
H Lundbeck As |
Anti-cgrp kompozicije i njihova upotreba
|
US10166295B2
(en)
|
2011-06-02 |
2019-01-01 |
Opko Biologics Ltd. |
Pegylated OXM variants
|
WO2012168259A1
(en)
|
2011-06-06 |
2012-12-13 |
Novartis Forschungsstiftung, Zweigniederlassung |
Protein tyrosine phosphatase, non-receptor type 11 (ptpn11) and triple-negative breast cancer
|
US9486507B2
(en)
|
2011-06-10 |
2016-11-08 |
Biogen Ma Inc. |
Pro-coagulant compounds and methods of use thereof
|
US9993529B2
(en)
|
2011-06-17 |
2018-06-12 |
Halozyme, Inc. |
Stable formulations of a hyaluronan-degrading enzyme
|
KR101676543B1
(ko)
|
2011-06-17 |
2016-11-15 |
할로자임, 아이엔씨 |
히알루로난 분해효소를 이용한 연속적인 피하 인슐린 주입 방법
|
WO2013003593A1
(en)
|
2011-06-28 |
2013-01-03 |
Alternative Innovative Technologies Llc |
Methods of use of hsp70 for increased performance or hsp70 related disorders
|
KR20140054009A
(ko)
|
2011-07-01 |
2014-05-08 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
릴랙신 융합 폴리펩타이드 및 그의 용도
|
PT2717917T
(pt)
|
2011-07-05 |
2016-07-27 |
Bioasis Technologies Inc |
Conjugados de anticorpos p97
|
WO2013040501A1
(en)
|
2011-09-16 |
2013-03-21 |
Pharmathene, Inc. |
Compositions and combinations of organophosphorus bioscavengers and hyaluronan-degrading enzymes, and uses thereof
|
RU2014114849A
(ru)
|
2011-10-14 |
2015-11-20 |
Алтернатив Инновейтив Текнолоджиз Ллц |
Устойчивые к деградации производные белков теплового шока-70 (бтш70) и способы их применения (варианты)
|
EP2771028A2
(en)
|
2011-10-24 |
2014-09-03 |
Halozyme, Inc. |
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
|
US20140314787A1
(en)
|
2011-11-08 |
2014-10-23 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute |
Treatment for neurodegenerative diseases
|
WO2013068432A1
(en)
|
2011-11-08 |
2013-05-16 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research |
Early diagnostic of neurodegenerative diseases
|
RU2685867C2
(ru)
|
2011-12-15 |
2019-04-23 |
Алтернатив Инновейтив Текнолоджиз Ллц |
Гибридные белки и белковые конъюгаты на основе белка теплового шока-70 (БТШ70) и способы их применения (варианты)
|
DK3130347T3
(da)
|
2011-12-30 |
2019-10-14 |
Halozyme Inc |
PH20-polypeptidvarianter, formuleringer og anvendelser deraf
|
EP2800583A1
(en)
|
2012-01-02 |
2014-11-12 |
Novartis AG |
Cdcp1 and breast cancer
|
PT2804623T
(pt)
|
2012-01-12 |
2019-11-18 |
Bioverativ Therapeutics Inc |
Polipéptidos quiméricos do fator viii e suas utilizações
|
CA2864126A1
(en)
|
2012-02-15 |
2013-08-22 |
Biogen Idec Ma Inc. |
Recombinant factor viii proteins
|
LT3564260T
(lt)
|
2012-02-15 |
2023-01-10 |
Bioverativ Therapeutics Inc. |
Viii faktoriaus kompozicijos ir jų gamybos bei panaudojimo būdai
|
CN104136626B
(zh)
|
2012-03-01 |
2017-05-03 |
诺沃—诺迪斯克有限公司 |
N‑末端修饰的寡肽及其用途
|
US20150266961A1
(en)
|
2012-03-29 |
2015-09-24 |
Novartis Forschungsstiftung, Zweigniederlassung, Fridrich Miescher Institute |
Inhibition of interleukin-8 and/or its receptor cxcr1 in the treatment of her2/her3-overexpressing breast cancer
|
AU2013243873B2
(en)
|
2012-04-04 |
2016-08-25 |
Halozyme, Inc. |
Combination therapy with an anti - hyaluronan agent and a tumor - targeted taxane
|
EP2838552A4
(en)
|
2012-04-19 |
2016-05-18 |
Opko Biolog Ltd |
OXYNTOMODULIN VARIANTS WITH EXTENDED ACTION AND PROCESSES FOR PRODUCING SAME
|
US9783610B2
(en)
|
2012-04-27 |
2017-10-10 |
The Trustees Of The University Of Pennsylvania |
Anti-tumor endothelial marker-1 (TEM1) antibody variants and uses thereof
|
WO2013164375A1
(en)
|
2012-05-01 |
2013-11-07 |
Novo Nordisk A/S |
Pharmaceutical composition
|
PE20150181A1
(es)
|
2012-06-04 |
2015-02-28 |
Opko Biolog Ltd |
Variantes de oxm pegilada
|
JP2015525222A
(ja)
|
2012-06-08 |
2015-09-03 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
キメラ性凝固因子
|
SI2859017T1
(sl)
|
2012-06-08 |
2019-05-31 |
Sutro Biopharma, Inc. |
Protitelesa, ki vsebujejo specifične nenaravne aminokislinske ostanke, postopki njihove priprave in postopki njihove uporabe
|
EP4079316A1
(en)
|
2012-06-08 |
2022-10-26 |
Bioverativ Therapeutics Inc. |
Procoagulant compounds
|
GB201210770D0
(en)
*
|
2012-06-18 |
2012-08-01 |
Polytherics Ltd |
Novel conjugation reagents
|
WO2014004639A1
(en)
|
2012-06-26 |
2014-01-03 |
Sutro Biopharma, Inc. |
Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
WO2014001482A1
(en)
|
2012-06-29 |
2014-01-03 |
Novartis Forschungsstiftung, Zweigniererlassung, Friedrich Miescher Institute For Biomedical Research |
Treating diseases by modulating a specific isoform of mkl1
|
US20150184154A1
(en)
|
2012-07-05 |
2015-07-02 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Resear |
New treatment for neurodegenerative diseases
|
BR112015000267B1
(pt)
|
2012-07-11 |
2023-01-24 |
Bioverativ Therapeutics Inc. |
Proteínas quiméricas, e composição farmacêutica
|
EP3539563A1
(en)
|
2012-07-19 |
2019-09-18 |
Redwood Bioscience, Inc. |
Antibody specific for cd22 and methods of use thereof
|
ES2647082T3
(es)
|
2012-07-31 |
2017-12-19 |
Bioasis Technologies Inc |
Proteínas desfosforiladas de la enfermedad de depósito lisosómico y métodos de uso de las mismas
|
HUE048780T2
(hu)
|
2012-08-16 |
2020-09-28 |
Ipierian Inc |
Tauopátia kezelésére szolgáló módszerek
|
ES2907763T3
(es)
|
2012-08-31 |
2022-04-26 |
Sutro Biopharma Inc |
Aminoácidos modificados que comprenden un grupo azido
|
WO2014062856A1
(en)
|
2012-10-16 |
2014-04-24 |
Halozyme, Inc. |
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
|
WO2014066744A2
(en)
|
2012-10-25 |
2014-05-01 |
True North Therapeutics, Inc. |
Anti-complement c1s antibodies and uses thereof
|
US8945562B2
(en)
|
2012-11-02 |
2015-02-03 |
True North Therapeutics, Inc. |
Anti-complement C1s antibodies
|
WO2014074218A1
(en)
|
2012-11-12 |
2014-05-15 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
EP2920148B1
(en)
|
2012-11-16 |
2019-06-12 |
The Regents of the University of California |
Pictet-spengler ligation for protein chemical modification
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
US8859705B2
(en)
|
2012-11-19 |
2014-10-14 |
Actamax Surgical Materials Llc |
Hydrogel tissue adhesive having decreased gelation time and decreased degradation time
|
WO2014080401A2
(en)
|
2012-11-20 |
2014-05-30 |
Prolor Biotech Inc |
Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
|
WO2014080350A1
(en)
|
2012-11-21 |
2014-05-30 |
The Governors Of The University Of Alberta |
Immunomodulatory peptides and methods of use thereof
|
EP3907237A1
(en)
|
2012-12-20 |
2021-11-10 |
Amgen Inc. |
Apj receptor agonists and uses thereof
|
US9675678B2
(en)
|
2013-01-29 |
2017-06-13 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods for treatment of homocystinuria
|
WO2014118382A1
(en)
|
2013-02-04 |
2014-08-07 |
W. L. Gore & Associates, Inc. |
Coating for substrate
|
US9272075B2
(en)
|
2013-02-04 |
2016-03-01 |
W.L. Gore & Associates, Inc. |
Coating for substrate
|
US10344060B2
(en)
|
2013-03-12 |
2019-07-09 |
Amgen Inc. |
Potent and selective inhibitors of Nav1.7
|
CA2906003C
(en)
|
2013-03-13 |
2021-07-06 |
Bioasis Technologies Inc. |
Fragments of p97 and uses thereof
|
US9694069B2
(en)
|
2013-03-14 |
2017-07-04 |
Alere San Diego, Inc. |
6-acetylmorphine analogs, and methods for their synthesis and use
|
EP2970499B1
(en)
|
2013-03-15 |
2022-08-10 |
Novo Nordisk A/S |
Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
|
US9458292B2
(en)
|
2013-03-27 |
2016-10-04 |
Nof Corporation |
Method for purifying polyethylene glycol having one amino group
|
BR112015026122A8
(pt)
|
2013-04-18 |
2020-01-21 |
Armo Biosciences Inc |
agente de polietileno glicol-il-10 (peg-il-10), seu uso, composição farmacêutica, contentor estéril e kit
|
AU2014257131B9
(en)
|
2013-04-23 |
2019-12-05 |
Nizyme, Inc. |
Methods and compositions for treating diseases
|
EA039554B1
(ru)
|
2013-06-10 |
2022-02-09 |
АйПИЕРИАН, ИНК. |
Способ снижения уровней a40 и/или a42 в нервной клетке и/или во внеклеточной жидкости
|
US9823255B2
(en)
|
2013-06-17 |
2017-11-21 |
Armo Biosciences, Inc. |
Method for assessing protein identity and stability
|
NZ713904A
(en)
|
2013-06-28 |
2022-02-25 |
Bioverativ Therapeutics Inc |
Thrombin cleavable linker with xten and its uses thereof
|
TWI753471B
(zh)
|
2013-07-03 |
2022-01-21 |
美商艾爾德生物製藥股份有限公司 |
使用抗cgrp抗體之葡萄糖代謝的調節
|
TW201534726A
(zh)
|
2013-07-03 |
2015-09-16 |
Halozyme Inc |
熱穩定ph20玻尿酸酶變異體及其用途
|
EP3019522B1
(en)
|
2013-07-10 |
2017-12-13 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
US20160184474A1
(en)
|
2013-07-29 |
2016-06-30 |
Actamax Surgical Materials, Llc |
Low swell tissue adhesive and sealant formulations
|
ES2761587T3
(es)
|
2013-08-07 |
2020-05-20 |
Friedrich Miescher Institute For Biomedical Res |
Nuevo método de cribado para el tratamiento de la ataxia de Friedreich
|
TW202003554A
(zh)
|
2013-08-14 |
2020-01-16 |
美商百歐維拉提夫治療公司 |
因子viii-xten融合物及其用途
|
EP3038657A2
(en)
|
2013-08-28 |
2016-07-06 |
Bioasis Technologies Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
US10010588B2
(en)
|
2013-08-30 |
2018-07-03 |
Armo Biosciences, Inc. |
Methods of using pegylated interleukin-10 for treating hyperlipidemia
|
HUE052447T2
(hu)
|
2013-09-08 |
2021-04-28 |
Kodiak Sciences Inc |
A VIII. tényezõs zwitterionos polimer konjugációk
|
EP3048899B1
(en)
|
2013-09-25 |
2021-09-08 |
Bioverativ Therapeutics Inc. |
On-column viral inactivation methods
|
WO2015054658A1
(en)
|
2013-10-11 |
2015-04-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
US20150158926A1
(en)
|
2013-10-21 |
2015-06-11 |
Opko Biologics, Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
EP3065769A4
(en)
|
2013-11-08 |
2017-05-31 |
Biogen MA Inc. |
Procoagulant fusion compound
|
US11413332B2
(en)
|
2013-11-11 |
2022-08-16 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
CA2931396C
(en)
|
2013-11-27 |
2022-09-06 |
Ipierian, Inc. |
An anti-tau antibody for treating tauopothy
|
JP6745218B2
(ja)
|
2013-11-27 |
2020-08-26 |
レッドウッド バイオサイエンス, インコーポレイテッド |
ヒドラジニル−ピロロ化合物及び複合体を生成するための方法
|
CN116621991A
(zh)
|
2014-01-10 |
2023-08-22 |
比奥贝拉蒂治疗公司 |
因子viii嵌合蛋白及其用途
|
US10293043B2
(en)
|
2014-06-02 |
2019-05-21 |
Armo Biosciences, Inc. |
Methods of lowering serum cholesterol
|
ES2950789T3
(es)
|
2014-06-10 |
2023-10-13 |
Amgen Inc |
Polipéptidos de apelina
|
WO2015189816A1
(en)
|
2014-06-13 |
2015-12-17 |
Friedrich Miescher Institute For Biomedical Research |
New treatment against influenza virus
|
EP3157535A1
(en)
|
2014-06-23 |
2017-04-26 |
Friedrich Miescher Institute for Biomedical Research |
Methods for triggering de novo formation of heterochromatin and or epigenetic silencing with small rnas
|
HUE043847T2
(hu)
|
2014-08-28 |
2019-09-30 |
Halozyme Inc |
Hialuronán-lebontó enzimmel és egy immun checkpoint inhibitorral végzett kombinációs terápia
|
WO2016046768A1
(en)
|
2014-09-24 |
2016-03-31 |
Friedrich Miescher Institute For Biomedical Research |
Lats and breast cancer
|
JP2018500272A
(ja)
|
2014-09-26 |
2018-01-11 |
バイエル ファーマ アクチエンゲゼルシャフト |
安定化アドレノメデュリン誘導体およびその使用
|
DK3207130T3
(da)
|
2014-10-14 |
2019-11-11 |
Halozyme Inc |
Sammensætninger af Adenosin Deaminase-2 (ADA2), varianter deraf og fremgangsmåder til anvendelse af samme
|
WO2016060996A2
(en)
|
2014-10-14 |
2016-04-21 |
Armo Biosciences, Inc. |
Interleukin-15 compositions and uses thereof
|
WO2016064817A1
(en)
|
2014-10-22 |
2016-04-28 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
MA40835A
(fr)
|
2014-10-23 |
2017-08-29 |
Biogen Ma Inc |
Anticorps anti-gpiib/iiia et leurs utilisations
|
US10517929B2
(en)
|
2014-10-23 |
2019-12-31 |
Ngm Biopharmaceuticals, Inc. |
Pharmaceutical compositions comprising FGF19 variants
|
KR20240024362A
(ko)
|
2014-10-24 |
2024-02-23 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 fgf-21 폴리펩티드 및 그의 용도
|
MA40861A
(fr)
|
2014-10-31 |
2017-09-05 |
Biogen Ma Inc |
Anticorps anti-glycoprotéines iib/iiia
|
KR102540109B1
(ko)
|
2014-11-06 |
2023-06-02 |
파마에센시아 코퍼레이션 |
Peg화된 인터페론의 투약 요법
|
EP3221334B1
(en)
|
2014-11-19 |
2020-02-19 |
Nzp Uk Limited |
6.alpha.-alkyl-6,7-dione steroids as intermediates for the production of steroidal fxr modulators
|
KR102546748B1
(ko)
|
2014-11-19 |
2023-06-22 |
엔제트피 유케이 리미티드 |
스테로이드 FXR 조절인자를 제조하기 위한 중간체로서의 6α-알킬-3,7-다이온 스테로이드
|
TWI686400B
(zh)
|
2014-11-19 |
2020-03-01 |
英商Nzp英國有限公司 |
化合物(二)
|
PL3221331T3
(pl)
|
2014-11-19 |
2020-03-31 |
NZP UK Limited |
Steroidy, 6-alkilo-7-hydroksy-4-en-3-ony jako związki pośrednie do wytwarzania steroidowych modulatorów fxr
|
ES2848376T3
(es)
|
2014-11-19 |
2021-08-09 |
Axon Neuroscience Se |
Anticuerpos de tau humanizados en la enfermedad de Alzheimer
|
TW201629098A
(zh)
|
2014-12-19 |
2016-08-16 |
艾爾德生物製藥股份有限公司 |
人類化抗 acth 抗體及其用途
|
US10618970B2
(en)
|
2015-02-03 |
2020-04-14 |
Armo Biosciences, Inc. |
Method of treating cancer with IL-10 and antibodies that induce ADCC
|
DK3288577T3
(da)
|
2015-05-01 |
2022-01-10 |
Allysta Pharmaceuticals Inc |
Adiponectin-peptidomimetika til behandling af øjenlidelser
|
AU2016268403A1
(en)
|
2015-05-28 |
2017-12-07 |
Armo Biosciences, Inc. |
Pegylated interleukin-10 for use in treating cancer
|
CA2986774A1
(en)
|
2015-05-29 |
2016-12-08 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
EP3302571B1
(en)
|
2015-05-29 |
2020-11-18 |
OPKO Biologics Ltd. |
Pegylated oxyntomodulin variants
|
SI3307296T1
(sl)
|
2015-06-15 |
2022-04-29 |
The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel |
TIMP2 za uporabo pri zdravljenju s starostjo povezanih stanj
|
CN113289009A
(zh)
|
2015-06-19 |
2021-08-24 |
Opko生物科学有限公司 |
长效凝固因子及其产生方法
|
EA201890423A1
(ru)
|
2015-08-03 |
2018-07-31 |
Биовератив Терапьютикс Инк. |
Слитые белки фактора ix, способы их получения и применения
|
BR112018002838A2
(pt)
|
2015-08-12 |
2019-01-15 |
Cell Machines Inc |
complexo do fator de coagulação, kit, método de tratamento
|
EP3341012A4
(en)
|
2015-08-25 |
2019-03-20 |
Armo Biosciences, Inc. |
METHOD FOR USE OF INTERLEUKIN-10 FOR THE TREATMENT OF ILLNESSES AND SUFFERING
|
WO2017037203A1
(en)
|
2015-09-02 |
2017-03-09 |
Immutep S.A.S. |
Anti-LAG-3 Antibodies
|
WO2017059338A1
(en)
*
|
2015-10-02 |
2017-04-06 |
Cornell University |
Enzyme-responsive peptide nanofiber compositions and uses thereof
|
WO2017072669A1
(en)
|
2015-10-28 |
2017-05-04 |
Friedrich Miescher Institute For Biomedical Research |
Tenascin-w and biliary tract cancers
|
PT3373922T
(pt)
|
2015-11-09 |
2022-03-28 |
Univ Colorado Regents |
Composições e métodos para usar no tratamento de homocistinúria
|
JP6728352B2
(ja)
|
2015-11-09 |
2020-07-22 |
エヌジーエム バイオファーマシューティカルス,インコーポレーテッド |
胆汁酸に関係した障害の治療方法
|
SG11201806419RA
(en)
|
2016-01-27 |
2018-08-30 |
Sutro Biopharma Inc |
Anti-cd74 antibody conjugates, compositions comprising anti-cd74 antibody conjugates and methods of using anti-cd74 antibody conjugates
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
IL262010B
(en)
|
2016-04-04 |
2022-09-01 |
Bioverativ Usa Inc |
Anti-complement factor bb antibodies and their uses
|
SG11201808630WA
(en)
|
2016-04-15 |
2018-10-30 |
Alder Biopharmaceuticals Inc |
Humanized anti-pacap antibodies and uses thereof
|
GB201608777D0
(en)
|
2016-05-18 |
2016-06-29 |
Dextra Lab Ltd |
Compounds
|
CA3024622A1
(en)
|
2016-05-18 |
2017-11-23 |
Alere San Diego, Inc. |
2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine analogs and methods for their synthesis and use
|
GB201608776D0
(en)
|
2016-05-18 |
2016-06-29 |
Dextra Lab Ltd |
Methods and compounds
|
US20190160152A1
(en)
|
2016-06-09 |
2019-05-30 |
Opko Biologics Ltd. |
Long-acting oxyntomodulin formulation and methods of producing and administering same
|
CN118085104A
(zh)
|
2016-07-11 |
2024-05-28 |
Opko生物科学有限公司 |
长效凝血因子及其制备方法
|
CN109891237B
(zh)
|
2016-10-24 |
2022-08-23 |
诺和诺德股份有限公司 |
胰岛素制剂的生物测定法
|
US20210308277A1
(en)
|
2016-11-14 |
2021-10-07 |
Hangzhou Dac Biotech Co., Ltd. |
Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
MA47163A
(fr)
|
2016-12-16 |
2019-11-06 |
Biogen Ma Inc |
Facteur 11 de différenciation de croissance activé protéolytiquement stabilisé
|
SG10201912034UA
(en)
|
2017-02-08 |
2020-02-27 |
Bristol Myers Squibb Co |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
JP6935059B2
(ja)
|
2017-03-30 |
2021-09-15 |
日油株式会社 |
カルボキシル基を一つ有するポリエチレングリコールの精製方法
|
US11324811B2
(en)
|
2017-04-17 |
2022-05-10 |
The Regents Of The University Of Colorado, A Body Corporate |
Optimization of enzyme replacement therapy for treatment of homocystinuria
|
WO2018231706A1
(en)
|
2017-06-11 |
2018-12-20 |
Molecular Express, Inc. |
Methods and compositions for substance use disorder vaccine formulations and uses thereof
|
KR102675270B1
(ko)
|
2017-06-22 |
2024-06-17 |
버텍스 파마슈티칼스 인코포레이티드 |
변형된 막 유형 세린 프로테아제 1(mtsp-1) 폴리펩티드 및 사용 방법
|
WO2019023316A1
(en)
|
2017-07-26 |
2019-01-31 |
Sutro Biopharma, Inc. |
METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN THE TREATMENT OF A T CELL LYMPHOMA
|
EP3664828A1
(en)
|
2017-08-10 |
2020-06-17 |
Friedrich Miescher Institute for Biomedical Research |
Hdac6 and protein aggregation
|
SG11202002310UA
(en)
|
2017-09-18 |
2020-04-29 |
Sutro Biopharma Inc |
Anti- folate receptor alpha antibody conjugates and their uses
|
EP3706779B1
(en)
|
2017-11-10 |
2022-12-14 |
Armo Biosciences, Inc. |
Compositions and methods of use of interleukin-10 in combination with immune checkpoint pathway inhibitors
|
US11492493B2
(en)
|
2017-12-26 |
2022-11-08 |
Becton, Dickinson And Company |
Deep ultraviolet-excitable water-solvated polymeric dyes
|
EP3774861A1
(en)
|
2018-03-28 |
2021-02-17 |
Bristol-Myers Squibb Company |
Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
|
WO2019191482A1
(en)
|
2018-03-30 |
2019-10-03 |
Becton, Dickinson And Company |
Water-soluble polymeric dyes having pendant chromophores
|
WO2019211842A1
(en)
|
2018-04-30 |
2019-11-07 |
Opko Biologics Ltd. |
Long-acting human growth hormone-antagonists and methods of producing the same
|
WO2019222435A1
(en)
|
2018-05-16 |
2019-11-21 |
Halozyme, Inc. |
Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
|
SG11202010767SA
(en)
|
2018-05-18 |
2020-11-27 |
Bioverativ Therapeutics Inc |
Methods of treating hemophilia a
|
EP3810189A1
(en)
|
2018-06-19 |
2021-04-28 |
Armo Biosciences, Inc. |
Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy
|
EP3817720A2
(en)
|
2018-07-03 |
2021-05-12 |
Bristol-Myers Squibb Company |
Fgf21 formulations
|
EP3813867A1
(en)
|
2018-07-22 |
2021-05-05 |
Bioasis Technologies Inc. |
Treatment of lymmphatic metastases
|
CA3111576A1
(en)
|
2018-09-11 |
2020-03-19 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and their uses
|
US20220047716A1
(en)
|
2018-09-17 |
2022-02-17 |
Sutro Biopharma, Inc. |
Combination therapies with anti-folate receptor antibody conjugates
|
AU2019361206A1
(en)
|
2018-10-19 |
2021-06-03 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
US11613744B2
(en)
|
2018-12-28 |
2023-03-28 |
Vertex Pharmaceuticals Incorporated |
Modified urokinase-type plasminogen activator polypeptides and methods of use
|
AU2019413431A1
(en)
|
2018-12-28 |
2021-07-08 |
Vertex Pharmaceuticals Incorporated |
Modified urokinase-type plasminogen activator polypeptides and methods of use
|
CA3129576A1
(en)
|
2019-02-11 |
2020-08-20 |
Opko Biologics Ltd. |
Long-acting glp-2 analogs
|
KR20210136014A
(ko)
|
2019-02-12 |
2021-11-16 |
암브룩스, 인코포레이티드 |
항체-tlr 작용제 콘쥬게이트를 함유하는 조성물, 방법 및 이의 용도
|
WO2020227105A1
(en)
|
2019-05-03 |
2020-11-12 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
US20220242871A1
(en)
|
2019-06-10 |
2022-08-04 |
Sutro Biopharma, Inc. |
5H-PYRROLO[3,2-d]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF
|
WO2020257235A1
(en)
|
2019-06-17 |
2020-12-24 |
Sutro Biopharma, Inc. |
1-(4-(aminomethyl)benzyl)-2-butyl-2h-pyrazolo[3,4-c]quinolin-4-amine derivatives and related compounds as toll-like receptor (tlr) 7/8 agonists, as well as antibody drug conjugates thereof for use in cancer therapy and diagnosis
|
EP3986918A1
(en)
|
2019-06-18 |
2022-04-27 |
Bayer Aktiengesellschaft |
Adrenomedullin-analogues for long-term stabilization and their use
|
CN115551530A
(zh)
|
2019-08-27 |
2022-12-30 |
通尼克斯制药有限公司 |
经修饰的tff2多肽
|
CN114786731A
(zh)
|
2019-10-10 |
2022-07-22 |
科达制药股份有限公司 |
治疗眼部病症的方法
|
EP4087612A1
(en)
|
2020-01-08 |
2022-11-16 |
Bristol-Myers Squibb Company |
Fgf-21 conjugate formulations
|
EP4114852A1
(en)
|
2020-03-03 |
2023-01-11 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
AU2021233909A1
(en)
|
2020-03-11 |
2022-09-29 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
SG10202003296VA
(en)
|
2020-04-06 |
2021-11-29 |
H Lundbeck As |
Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies
|
AU2021265205A1
(en)
|
2020-04-30 |
2023-01-05 |
Academisch Ziekenhuis Groningen |
Anti-CD103 antibodies
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
EP4192495A1
(en)
|
2020-08-07 |
2023-06-14 |
Bristol-Myers Squibb Company |
Fgf21 combined with ccr2/5 antagonists for the treatment of fibrosis
|
EP3954393A1
(en)
|
2020-08-13 |
2022-02-16 |
Bioasis Technologies Inc. |
Combination therapies for delivery across the blood brain barrier
|
JP2023538071A
(ja)
|
2020-08-20 |
2023-09-06 |
アンブルックス,インコーポレイテッド |
抗体-tlrアゴニストコンジュゲート、その方法及び使用
|
WO2022103983A2
(en)
|
2020-11-11 |
2022-05-19 |
Sutro Biopharma, Inc. |
Fluorenylmethyloxycarbonyl and fluorenylmethylaminocarbonyl compounds, protein conjugates thereof, and methods for their use
|
WO2022115597A1
(en)
|
2020-11-25 |
2022-06-02 |
Bristol-Myers Squibb Company |
Methods of treating liver diseases
|
EP4313163A1
(en)
|
2021-04-03 |
2024-02-07 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|
WO2022232488A1
(en)
|
2021-04-30 |
2022-11-03 |
Celgene Corporation |
Combination therapies using an anti-bcma antibody drug conjugate (adc) in combination with a gamma secretase inhibitor (gsi)
|
KR20240046872A
(ko)
|
2021-08-20 |
2024-04-11 |
바이엘 악티엔게젤샤프트 |
Peg화 아드레노메둘린의 제조 방법, 그의 중간체 및 그의 용도
|
IL310885A
(en)
|
2021-08-27 |
2024-04-01 |
H Lundbeck As |
Treatment of cluster headache using anti-CGRP antibodies
|
EP4155349A1
(en)
|
2021-09-24 |
2023-03-29 |
Becton, Dickinson and Company |
Water-soluble yellow green absorbing dyes
|
WO2024006272A1
(en)
|
2022-06-27 |
2024-01-04 |
Sutro Biopharma, Inc. |
β-GLUCURONIDE LINKER-PAYLOADS, PROTEIN CONJUGATES THEREOF, AND METHODS THEREOF
|
TW202408589A
(zh)
|
2022-06-30 |
2024-03-01 |
美商舒卓生物製藥公司 |
抗ror1抗體及抗體結合物、包含抗ror1抗體或抗體結合物之組合物,及製造及使用抗ror1抗體及抗體結合物之方法
|
WO2024007016A2
(en)
|
2022-07-01 |
2024-01-04 |
Beckman Coulter, Inc. |
Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
|
WO2024015229A1
(en)
|
2022-07-15 |
2024-01-18 |
Sutro Biopharma, Inc. |
Protease/enzyme cleavable linker-payloads and protein conjugates
|
WO2024044780A1
(en)
|
2022-08-26 |
2024-02-29 |
Sutro Biopharma, Inc. |
Interleukin-18 variants and uses thereof
|
WO2024044327A1
(en)
|
2022-08-26 |
2024-02-29 |
Beckman Coulter, Inc. |
Dhnt monomers and polymer dyes with modified photophysical properties
|
WO2024098023A2
(en)
|
2022-11-04 |
2024-05-10 |
Sutro Biopharma, Inc. |
Interferon alpha polypeptides and conjugates
|
WO2024171078A1
(en)
|
2023-02-14 |
2024-08-22 |
H. Lundbeck A/S |
Treatment of opiod-induced pain
|