DK3288577T3 - Adiponectin-peptidomimetika til behandling af øjenlidelser - Google Patents

Adiponectin-peptidomimetika til behandling af øjenlidelser Download PDF

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Publication number
DK3288577T3
DK3288577T3 DK16789840.2T DK16789840T DK3288577T3 DK 3288577 T3 DK3288577 T3 DK 3288577T3 DK 16789840 T DK16789840 T DK 16789840T DK 3288577 T3 DK3288577 T3 DK 3288577T3
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DK
Denmark
Prior art keywords
treatment
eye disorders
adiponectin peptidomimetics
adiponectin
peptidomimetics
Prior art date
Application number
DK16789840.2T
Other languages
English (en)
Inventor
Henry Hsu
Original Assignee
Allysta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allysta Pharmaceuticals Inc filed Critical Allysta Pharmaceuticals Inc
Application granted granted Critical
Publication of DK3288577T3 publication Critical patent/DK3288577T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
DK16789840.2T 2015-05-01 2016-04-29 Adiponectin-peptidomimetika til behandling af øjenlidelser DK3288577T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562156127P 2015-05-01 2015-05-01
PCT/US2016/030142 WO2016179007A1 (en) 2015-05-01 2016-04-29 Adiponectin peptidomimetics for treating ocular disorders

Publications (1)

Publication Number Publication Date
DK3288577T3 true DK3288577T3 (da) 2022-01-10

Family

ID=57218292

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16789840.2T DK3288577T3 (da) 2015-05-01 2016-04-29 Adiponectin-peptidomimetika til behandling af øjenlidelser

Country Status (13)

Country Link
US (6) US10987401B2 (da)
EP (3) EP4014985A1 (da)
JP (1) JP7245649B2 (da)
KR (2) KR20170141692A (da)
CN (3) CN107530396B (da)
AU (3) AU2016257724B2 (da)
CA (3) CA3191203A1 (da)
DK (1) DK3288577T3 (da)
ES (1) ES2903448T3 (da)
HK (1) HK1246178A1 (da)
IL (1) IL272449A (da)
SG (1) SG11202001140UA (da)
WO (2) WO2016179007A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4014985A1 (en) 2015-05-01 2022-06-22 Allysta Pharmaceuticals, Inc. Adiponectin peptidomimetics for treating ocular disorders
SG11201907579VA (en) * 2017-03-09 2019-09-27 Allysta Pharmaceuticals Inc Peptides for dry eye disease
CN107149676A (zh) * 2017-05-05 2017-09-12 杨硕 脂联素和脂联素/胰岛素混合液在改善及治疗眼表角膜上皮及神经损伤中的应用
WO2019061491A1 (en) * 2017-09-30 2019-04-04 Pro Sunfun Biotech Research And Development Co., Ltd. PEPTIDE FOR OCULAR CARE, COMPOSITION AND METHOD OF USE THEREOF
CN109912685B (zh) * 2017-12-13 2022-05-06 三凡生技研发股份有限公司 眼睛保护胜肽及其组合物及使用该胜肽的用途
CA3095073A1 (en) * 2018-03-23 2019-09-26 Arch Biosurgery, Inc. Sap and peptidomimetics for treatment of eye disease
CA3116065A1 (en) * 2018-10-24 2020-04-30 Allysta Pharmaceuticals, Inc. Adiponectin peptidomimetics formulations
US11229549B2 (en) * 2019-09-18 2022-01-25 Vance M. Thompson Tear transplantation and multi-part contact lens with absorbent portion
US11931454B2 (en) 2019-09-18 2024-03-19 Alcon Inc. Wet-packed soft hydrogel ocular inserts
US11213551B1 (en) 2021-04-05 2022-01-04 Korb Research, Llc. Ocular treatment compositions and methods of use thereof
CA3234071A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023069255A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023107796A1 (en) * 2021-12-11 2023-06-15 The Regents Of The University Of California Ophthalmic formulations for macular degeneration
KR102609115B1 (ko) * 2023-06-08 2023-12-05 주식회사 엔큐라젠 펩타이드를 포함하는 안구 질환의 치료용 조성물

Family Cites Families (13)

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US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
DE4437604A1 (de) 1994-10-21 1996-04-25 Basf Ag Konjugate aus einem Poly- oder Oligopeptid und einer niedermolekularen lipophilen Verbindung
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
CA2330451A1 (en) 1998-04-28 1999-11-04 Applied Research Systems Ars Holding N.V. Polyol-ifn-beta conjugates
GB9814527D0 (en) 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system
CA2473781A1 (en) 2002-01-18 2003-07-31 Protemix Corporation Limited Glycoisoforms of adiponectin and uses thereof
EA200900786A1 (ru) * 2005-04-29 2009-10-30 Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье Пептид в качестве лекарственного средства и способ лечения патологий, связанных с воспалительными процессами, посредством пептида
US9073965B2 (en) * 2011-04-12 2015-07-07 Temple University—Of the Commonwealth System of Higher Education Adiponectin receptor agonists and methods of use
KR101438744B1 (ko) 2012-08-02 2014-09-15 전남대학교산학협력단 아디포넥틴을 유효성분으로 포함하는 안구건조증 또는 염증성 안구표면 질환의 예방 또는 치료용 조성물
PT2911623T (pt) * 2012-10-26 2019-11-21 Forsight Vision5 Inc Sistema oftálmico para libertação prolongada de fármaco no olho
EP4014985A1 (en) * 2015-05-01 2022-06-22 Allysta Pharmaceuticals, Inc. Adiponectin peptidomimetics for treating ocular disorders

Also Published As

Publication number Publication date
AU2016257724B2 (en) 2021-02-25
US20180078616A1 (en) 2018-03-22
CA3071670A1 (en) 2019-02-21
IL272449A (en) 2020-03-31
CN107530396A (zh) 2018-01-02
CN111032070A (zh) 2020-04-17
US20200085907A1 (en) 2020-03-19
US20230074446A1 (en) 2023-03-09
EP3668530A4 (en) 2021-07-21
EP3288577B1 (en) 2021-10-27
CA2981822C (en) 2023-04-11
US20210128671A1 (en) 2021-05-06
US20220331393A1 (en) 2022-10-20
AU2018318008A1 (en) 2020-02-06
KR20170141692A (ko) 2017-12-26
AU2016257724A1 (en) 2017-10-12
CN115919996A (zh) 2023-04-07
AU2021203254A1 (en) 2021-06-17
ES2903448T3 (es) 2022-04-01
US20180161390A1 (en) 2018-06-14
EP3288577A1 (en) 2018-03-07
JP2018514592A (ja) 2018-06-07
SG11202001140UA (en) 2020-03-30
US10537608B2 (en) 2020-01-21
CA3191203A1 (en) 2016-11-10
EP3668530A1 (en) 2020-06-24
CA2981822A1 (en) 2016-11-10
US11464825B2 (en) 2022-10-11
EP4014985A1 (en) 2022-06-22
KR20200039749A (ko) 2020-04-16
JP7245649B2 (ja) 2023-03-24
EP3288577A4 (en) 2018-12-26
HK1246178A1 (zh) 2018-09-07
WO2019036223A1 (en) 2019-02-21
US10987401B2 (en) 2021-04-27
WO2016179007A1 (en) 2016-11-10
CN107530396B (zh) 2022-08-26
US11273197B2 (en) 2022-03-15

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