LT1988910T - Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdas - Google Patents
Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdasInfo
- Publication number
- LT1988910T LT1988910T LTEP07752096.3T LT07752096T LT1988910T LT 1988910 T LT1988910 T LT 1988910T LT 07752096 T LT07752096 T LT 07752096T LT 1988910 T LT1988910 T LT 1988910T
- Authority
- LT
- Lithuania
- Prior art keywords
- acryloyloxyethylphosphorylcholine
- preparation
- containing polymer
- polymer conjugates
- conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
- C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77691606P | 2006-02-28 | 2006-02-28 | |
| PCT/US2007/005372 WO2007100902A2 (en) | 2006-02-28 | 2007-02-28 | Acryloyloxyethylphosphorylcholine containing polymer conjugates and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT1988910T true LT1988910T (lt) | 2018-01-10 |
Family
ID=38459678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP07752096.3T LT1988910T (lt) | 2006-02-28 | 2007-02-28 | Akriloiloksietilfosforilcholiną turintys polimero konjugatai ir jų gavimo būdas |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20100166700A1 (lt) |
| EP (2) | EP1988910B1 (lt) |
| JP (2) | JP5528710B2 (lt) |
| DK (1) | DK1988910T3 (lt) |
| ES (1) | ES2657628T3 (lt) |
| LT (1) | LT1988910T (lt) |
| PT (1) | PT1988910T (lt) |
| SI (1) | SI1988910T1 (lt) |
| WO (2) | WO2007100902A2 (lt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0301014D0 (en) * | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| JP5528710B2 (ja) | 2006-02-28 | 2014-06-25 | オリガシス コーポレイション | アクリロイルオキシエチルホスホリルコリン含有ポリマー抱合体及びその製法 |
| EP2334334A1 (en) | 2008-09-19 | 2011-06-22 | Nektar Therapeutics | Polymer conjugates of nesiritide peptides |
| DK2260873T3 (da) * | 2009-06-08 | 2019-09-16 | Biocompatibles Uk Ltd | Pcylering af proteiner |
| US8765432B2 (en) * | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| EP3549963B1 (en) * | 2010-04-15 | 2022-01-12 | Kodiak Sciences Inc. | High molecular weight zwitterion-containing polymers |
| CN101870735B (zh) * | 2010-06-02 | 2013-06-12 | 北京精益泰翔技术发展有限公司 | 一种新型高糖基化促红细胞生成素免疫融合蛋白 |
| WO2012061165A2 (en) * | 2010-10-25 | 2012-05-10 | Lu Xiandan Sharon | Methods and compositions for improving admet properties |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| KR102025848B1 (ko) | 2010-12-01 | 2019-11-05 | 앨더바이오 홀딩스 엘엘씨 | 항―ｎｇｆ 조성물 및 그의 용도 |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| KR20140082649A (ko) * | 2011-08-12 | 2014-07-02 | 아센디스 파마 에이에스 | 프로스타사이클린의 서방형 조성물 |
| US9901648B2 (en) * | 2012-01-27 | 2018-02-27 | The Regents Of The University Of California | Stabilization of biomolecules using sugar polymers |
| EP3712142B1 (en) | 2013-01-11 | 2022-07-06 | Corsair Pharma, Inc. | Prodrugs of treprostinil |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| US10702608B2 (en) | 2013-09-08 | 2020-07-07 | Kodiak Sciences Inc. | Factor VIII zwitterionic polymer conjugates |
| US9840553B2 (en) * | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| JP6849590B2 (ja) | 2014-10-17 | 2021-03-24 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート |
| WO2016085808A1 (en) | 2014-11-26 | 2016-06-02 | The Regents Of The University Of California | Stealth nanocapsules for protein delivery |
| US9394227B1 (en) | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| US9643911B2 (en) | 2015-06-17 | 2017-05-09 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| MA42692A (fr) | 2015-08-24 | 2018-07-04 | Glaxosmithkline Ip No 2 Ltd | Compositions biopharmaceutiques |
| SG11201805420SA (en) * | 2015-12-30 | 2018-07-30 | Kodiak Sciences Inc | Antibodies and conjugates thereof |
| US9695138B1 (en) | 2016-10-17 | 2017-07-04 | Acenda Pharma, Inc. | Phenothiazine derivatives and methods of use thereof |
| EP3610010A4 (en) | 2017-04-14 | 2021-02-24 | Kodiak Sciences Inc. | COMPLEMENT D-FACTOR ANTAGONIST ANTIBODIES AND THEIR CONJUGATES |
| CA3130763A1 (en) | 2019-02-25 | 2020-09-03 | Ginkgo Bioworks, Inc. | Biosynthesis of cannabinoids and cannabinoid precursors |
| CN110627937B (zh) * | 2019-09-27 | 2021-03-30 | 西北大学 | 仿细胞膜聚合物的制备方法、及其修饰壳聚糖-金自组装载药纳米粒子的制备方法和应用 |
| EP4041312A4 (en) | 2019-10-10 | 2023-12-20 | Kodiak Sciences Inc. | METHOD FOR TREATING AN EYE DISORDER |
| CN111978390B (zh) * | 2020-08-31 | 2022-10-14 | 上海景泽生物技术有限公司 | 聚乙二醇修饰的rhBNP及其用途 |
| WO2022255479A1 (ja) * | 2021-06-04 | 2022-12-08 | タグシクス・バイオ株式会社 | 中分子化合物の血中動態改善のための中分子化合物コンジュゲート体およびその製造方法 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162218A (en) | 1988-11-18 | 1992-11-10 | The Regents Of The University Of California | Conjugated polypeptides and methods for their preparation |
| US5643575A (en) * | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| GB9324033D0 (en) | 1993-11-23 | 1994-01-12 | Biocompatibles Ltd | Ethylenically unsaturated compounds |
| US5763548A (en) | 1995-03-31 | 1998-06-09 | Carnegie-Mellon University | (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization |
| US6541580B1 (en) | 1995-03-31 | 2003-04-01 | Carnegie Mellon University | Atom or group transfer radical polymerization |
| US5807937A (en) | 1995-11-15 | 1998-09-15 | Carnegie Mellon University | Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties |
| US5789487A (en) | 1996-07-10 | 1998-08-04 | Carnegie-Mellon University | Preparation of novel homo- and copolymers using atom transfer radical polymerization |
| US7125938B2 (en) | 1997-03-11 | 2006-10-24 | Carnegie Mellon University | Atom or group transfer radical polymerization |
| AU752946B2 (en) | 1997-10-16 | 2002-10-03 | Avigenics, Inc. | Vectors comprising a magnum-specific promoter for avian transgenesis |
| DE69932320T2 (de) | 1998-01-30 | 2007-07-12 | Albemarle Corp. | Maleimide enthaltende fotopolymerisierbare zusammensetzungen und verfahren zu deren verwendung |
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| US6153655A (en) * | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| US6384146B1 (en) * | 1999-04-05 | 2002-05-07 | The Research Foundation Of State University Of New York | Graft, graft-block, block-graft, and star-shaped copolymers and methods of making them |
| CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| US7049373B2 (en) | 1999-08-06 | 2006-05-23 | Carnegie Mellon University | Process for preparation of graft polymers |
| GB9928956D0 (en) * | 1999-12-07 | 2000-02-02 | Malik Navid | Internally supported biomimetic coating systems |
| IL144815A (en) | 2000-08-11 | 2005-07-25 | Sumitomo Chemical Co | Process for producing carbonyl or hydroxy compound |
| DE60129148T2 (de) | 2000-10-06 | 2008-02-28 | Biocompatibles Uk Ltd., Farnham | Zwitterionische polymere |
| WO2002028912A2 (en) | 2000-10-06 | 2002-04-11 | Carnegie Mellon University | Preparation of nanocomposite structures by controlled polymerization |
| EP1337563B1 (en) | 2000-10-06 | 2006-12-20 | Carnegie-Mellon University | Polymerization process for ionic monomers |
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| ATE471956T1 (de) * | 2001-01-30 | 2010-07-15 | Kyowa Hakko Kirin Co Ltd | Verzweigte polyalkylenglykole |
| AU2002307151A1 (en) | 2001-04-06 | 2002-10-21 | Carnegie Mellon University | A process for the preparation of nanostructured materials |
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| AU2002361223A1 (en) | 2001-08-27 | 2003-03-18 | Zeptosens Ag | Bioanalytical recognition surface with optimised recognition element density |
| WO2003031480A2 (en) | 2001-10-12 | 2003-04-17 | Carnegie Mellon University | Process for monomer sequence control in polymerizations |
| WO2003031481A2 (en) | 2001-10-12 | 2003-04-17 | Carnegie Mellon University | Simultaneous reverse and normal initiation of atrp |
| US6964859B2 (en) | 2001-10-16 | 2005-11-15 | Massachusetts Institute Of Technology | Suppressor tRNA system |
| US7026440B2 (en) * | 2001-11-07 | 2006-04-11 | Nektar Therapeutics Al, Corporation | Branched polymers and their conjugates |
| ATE371680T1 (de) | 2002-01-16 | 2007-09-15 | Biocompatibles Uk Ltd | Polymerkonjugate |
| DE60334779D1 (en) * | 2002-03-07 | 2010-12-16 | Biocompatibles Uk Ltd | Mit nucleinsäure complexierte block-copolymere |
| WO2003074026A1 (en) * | 2002-03-07 | 2003-09-12 | Biocompatibles Uk Limited | Drug carriers comprising amphiphilic block copolymers |
| JP4248189B2 (ja) | 2002-04-09 | 2009-04-02 | 株式会社資生堂 | ホスホリルコリン基含有多糖類及びその製造方法 |
| US20050180945A1 (en) | 2002-05-21 | 2005-08-18 | Chaikof Elliot L. | Multivalent polymers with chan-terminating binding groups |
| US7019082B2 (en) | 2002-08-09 | 2006-03-28 | Carnegie Mellon University | Polymers, supersoft elastomers and methods for preparing the same |
| EP1556090A1 (en) | 2002-09-25 | 2005-07-27 | Biocompatibles UK Limited | Polymer compositions for administration to animals |
| WO2004044023A1 (fr) | 2002-11-07 | 2004-05-27 | Rhodia Chimie | Copolymere a structure controlee presentant une partie amphotere ou zwitterionique. |
| GB0301014D0 (en) | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| US9040664B2 (en) * | 2003-04-11 | 2015-05-26 | Antriabio, Inc. | Materials and methods for preparing protein-polymer conjugates |
| GB0314472D0 (en) * | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| CA2537336C (en) | 2003-09-17 | 2013-02-26 | Nektar Therapeutics Al, Corporation | Multi-arm polymer prodrugs |
| WO2005058367A2 (en) | 2003-12-16 | 2005-06-30 | Nektar Therapeutics Al, Corporation | Pegylated small molecules |
| US20050208093A1 (en) | 2004-03-22 | 2005-09-22 | Thierry Glauser | Phosphoryl choline coating compositions |
| US7214759B2 (en) | 2004-11-24 | 2007-05-08 | Advanced Cardiovascular Systems, Inc. | Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same |
| US20070005130A1 (en) * | 2005-06-29 | 2007-01-04 | Thierry Glauser | Biodegradable polymer for coating |
| JP5096363B2 (ja) | 2005-12-16 | 2012-12-12 | ネクター セラピューティックス | Ｇｌｐ−１のポリマ複合体 |
| US7906134B2 (en) | 2005-12-21 | 2011-03-15 | Abbott Laboratories | Room temperature-curable polymers |
| JP5528710B2 (ja) | 2006-02-28 | 2014-06-25 | オリガシス コーポレイション | アクリロイルオキシエチルホスホリルコリン含有ポリマー抱合体及びその製法 |
| JP5557373B2 (ja) | 2006-11-21 | 2014-07-23 | アボット ラボラトリーズ | 薬剤溶出性コーティングにおけるテトラフルオロエチレン、ヘキサフルオロプロピレン、及びフッ化ビニリデンのターポリマーの使用 |
| WO2008098930A1 (en) * | 2007-02-14 | 2008-08-21 | Biocompatibes Uk Limited | Derivatisation of biological molecules |
| CA2679070C (en) | 2007-03-12 | 2016-04-26 | Nektar Therapeutics | Oligomer-antihistamine conjugates |
| EP2131865B1 (en) | 2007-03-12 | 2014-12-17 | Nektar Therapeutics | Oligomer-protease inhibitor conjugates |
| JP2010117189A (ja) | 2008-11-12 | 2010-05-27 | Sumitomo Bakelite Co Ltd | 生理活性物質固定化用基板 |
| WO2010068864A2 (en) | 2008-12-12 | 2010-06-17 | University Of Massachusetts | Polyesters with grafted zwitterions |
| US20100158850A1 (en) | 2008-12-23 | 2010-06-24 | The Regents Of The University Of Michigan | Dendrimer based modular platforms |
| DK2260873T3 (da) * | 2009-06-08 | 2019-09-16 | Biocompatibles Uk Ltd | Pcylering af proteiner |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| EP3549963B1 (en) | 2010-04-15 | 2022-01-12 | Kodiak Sciences Inc. | High molecular weight zwitterion-containing polymers |
| WO2013059137A1 (en) | 2011-10-17 | 2013-04-25 | Oligasis | High molecular weight zwitterion-containing polymers |
-
2007
- 2007-02-28 JP JP2008557399A patent/JP5528710B2/ja active Active
- 2007-02-28 LT LTEP07752096.3T patent/LT1988910T/lt unknown
- 2007-02-28 WO PCT/US2007/005372 patent/WO2007100902A2/en active Application Filing
- 2007-02-28 WO PCT/US2007/005381 patent/WO2007100905A2/en active Application Filing
- 2007-02-28 ES ES07752096.3T patent/ES2657628T3/es active Active
- 2007-02-28 SI SI200731999T patent/SI1988910T1/en unknown
- 2007-02-28 EP EP07752096.3A patent/EP1988910B1/en active Active
- 2007-02-28 PT PT77520963T patent/PT1988910T/pt unknown
- 2007-02-28 DK DK07752096.3T patent/DK1988910T3/en active
- 2007-02-28 EP EP17165316.5A patent/EP3222142A1/en active Pending
- 2007-02-28 US US12/281,071 patent/US20100166700A1/en not_active Abandoned
-
2013
- 2013-08-05 US US13/959,563 patent/US8846021B2/en active Active
- 2013-11-13 JP JP2013235314A patent/JP5745009B2/ja active Active
-
2014
- 2014-08-11 US US14/456,875 patent/US20150050714A1/en not_active Abandoned
-
2019
- 2019-05-28 US US16/424,265 patent/US20200000930A1/en not_active Abandoned
-
2021
- 2021-12-16 US US17/553,605 patent/US20220096643A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5745009B2 (ja) | 2015-07-08 |
| WO2007100905A3 (en) | 2008-10-16 |
| JP5528710B2 (ja) | 2014-06-25 |
| US20200000930A1 (en) | 2020-01-02 |
| EP1988910B1 (en) | 2017-12-06 |
| EP3222142A1 (en) | 2017-09-27 |
| SI1988910T1 (en) | 2018-02-28 |
| WO2007100902A2 (en) | 2007-09-07 |
| EP1988910A2 (en) | 2008-11-12 |
| WO2007100905A2 (en) | 2007-09-07 |
| US8846021B2 (en) | 2014-09-30 |
| US20100166700A1 (en) | 2010-07-01 |
| PT1988910T (pt) | 2018-02-07 |
| US20220096643A1 (en) | 2022-03-31 |
| JP2014043456A (ja) | 2014-03-13 |
| WO2007100902A3 (en) | 2008-11-20 |
| US20150050714A1 (en) | 2015-02-19 |
| DK1988910T3 (en) | 2018-01-22 |
| EP1988910A4 (en) | 2013-03-06 |
| US20130337534A1 (en) | 2013-12-19 |
| ES2657628T3 (es) | 2018-03-06 |
| JP2009532330A (ja) | 2009-09-10 |
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