BRPI0911249A2 - método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição - Google Patents

método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição

Info

Publication number
BRPI0911249A2
BRPI0911249A2 BRPI0911249A BRPI0911249A BRPI0911249A2 BR PI0911249 A2 BRPI0911249 A2 BR PI0911249A2 BR PI0911249 A BRPI0911249 A BR PI0911249A BR PI0911249 A BRPI0911249 A BR PI0911249A BR PI0911249 A2 BRPI0911249 A2 BR PI0911249A2
Authority
BR
Brazil
Prior art keywords
biomacromolecules
polyalkylene glycol
transition metals
isolation method
isolation
Prior art date
Application number
BRPI0911249A
Other languages
English (en)
Inventor
A Jaquez Orlando
S Gronke Robert
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of BRPI0911249A2 publication Critical patent/BRPI0911249A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Output Control And Ontrol Of Special Type Engine (AREA)
BRPI0911249A 2008-04-16 2009-04-16 método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição BRPI0911249A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7118208P 2008-04-16 2008-04-16
PCT/US2009/002390 WO2009128935A1 (en) 2008-04-16 2009-04-16 Method of isolating biomacromolecules using polyalkylene glycol and transition metals

Publications (1)

Publication Number Publication Date
BRPI0911249A2 true BRPI0911249A2 (pt) 2017-05-23

Family

ID=41199397

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911249A BRPI0911249A2 (pt) 2008-04-16 2009-04-16 método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição

Country Status (12)

Country Link
US (1) US20090292109A1 (pt)
EP (1) EP2288358B1 (pt)
JP (1) JP5631301B2 (pt)
CN (1) CN102065870B (pt)
AU (1) AU2009236653B2 (pt)
BR (1) BRPI0911249A2 (pt)
CA (1) CA2720048A1 (pt)
DK (1) DK2288358T3 (pt)
IL (1) IL208376A (pt)
MX (1) MX2010011206A (pt)
NZ (1) NZ588408A (pt)
WO (1) WO2009128935A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201505203XA (en) * 2013-02-26 2015-08-28 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
JP2016509069A (ja) * 2013-02-28 2016-03-24 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ 非イオン性有機ポリマー存在下、高導電率でのタンパク質精製
CN105209881B (zh) * 2013-03-13 2021-01-22 迈阿密大学 从细胞培养上清液和生物流体分离并纯化微泡的方法
EP3255054A1 (en) * 2016-06-06 2017-12-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the purification of biological macromolecular complexes
CA3054321A1 (en) 2017-02-27 2018-08-30 Translate Bio, Inc. Methods for purification of messenger rna
CN114432811B (zh) * 2022-01-14 2023-07-28 南昌大学 一种错端滤一体式复合滤筒除尘装置
WO2024059235A2 (en) 2022-09-16 2024-03-21 Amgen Inc. A method for harvesting products from perfusion cultures

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US3808189A (en) * 1973-03-15 1974-04-30 American Cyanamid Co Isolation of gamma globulin preparations enriched in iga and igm using polyethylene glycol
DK139056B (da) * 1976-04-06 1978-12-11 Nordisk Insulinlab Fremgangsmåde til udvinding af immunoglobulin, der er egnet til intravenøs indgivelse.
US4164495A (en) * 1976-04-06 1979-08-14 Nordisk Insulinlaboratorium Method of recovering immunoglobulin using a polyol and an alkanoic acid
DK25877A (da) * 1977-01-21 1978-08-15 Nordisk Insulinlab Fremgangsmaade til udvinding af renset albumin fra blodplasma
US4841024A (en) * 1986-09-15 1989-06-20 Becton Dickinson And Company Purification of antibodies
US4801687A (en) * 1986-10-27 1989-01-31 Bioprobe International, Inc. Monoclonal antibody purification process using protein A
DE68921982D1 (de) 1988-06-14 1995-05-04 Cetus Oncology Corp Kupplungsmittel und sterisch gehinderte, mit disulfid gebundene konjugate daraus.
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
US4933435A (en) * 1989-04-05 1990-06-12 Bioprobe International Antibody purification process
IE63847B1 (en) 1989-05-05 1995-06-14 Res Dev Foundation A novel antibody delivery system for biological response modifiers
US5151504A (en) * 1989-11-17 1992-09-29 E. R. Squibb & Sons, Inc. Method for purification of monoclonal antibodies
DE69120146T2 (de) 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
US5314995A (en) 1990-01-22 1994-05-24 Oncogen Therapeutic interleukin-2-antibody based fusion proteins
WO1991014438A1 (en) 1990-03-20 1991-10-03 The Trustees Of Columbia University In The City Of New York Chimeric antibodies with receptor binding ligands in place of their constant region
DK0447585T4 (da) * 1990-03-22 2003-09-01 Biotest Pharma Gmbh Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat
US5110913A (en) * 1990-05-25 1992-05-05 Miles Inc. Antibody purification method
US5135875A (en) * 1990-08-15 1992-08-04 Abbott Laboratories Protein precipitation reagent
WO1992008495A1 (en) 1990-11-09 1992-05-29 Abbott Biotech, Inc. Cytokine immunoconjugates
US5525519A (en) * 1992-01-07 1996-06-11 Middlesex Sciences, Inc. Method for isolating biomolecules from a biological sample with linear polymers
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5665570A (en) * 1994-02-10 1997-09-09 Takeda Chemical Industries, Ltd. Antibody-encoding recombinant DNA and its use
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US5641870A (en) * 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
DE19543737A1 (de) * 1995-11-24 1997-05-28 Hoechst Ag Verfahren zur Ultrafiltration von Peptide oder Proteine enthaltender biologischer Matrices
US5907035A (en) * 1996-05-23 1999-05-25 Baxter Biotech Technology Sarl Aqueous two-phase metal affinity partitioning protein purification system
ES2252986T3 (es) * 1998-10-07 2006-05-16 Trinity Biotech Manufacturing Ltd. Reactivos de tromboplastina y metodos para preparar y usar tales reactivos.
DE60021644D1 (de) * 1999-04-13 2005-09-08 Apc Europ S A Anwendung und Herstellungsverfahren von tierischen Gammaglobulin-reichen Plasmaprotein Mischungen
US7064191B2 (en) * 2000-10-06 2006-06-20 Kyowa Hakko Kogyo Co., Ltd. Process for purifying antibody
US6846410B2 (en) * 2002-05-03 2005-01-25 Zirchrom Separations, Inc. High stability porous metal oxide spherules used for one-step antibody purifications
GB0624227D0 (en) * 2006-12-05 2007-01-10 Common Services Agency Protein purification

Also Published As

Publication number Publication date
AU2009236653B2 (en) 2014-09-25
JP2011518156A (ja) 2011-06-23
WO2009128935A1 (en) 2009-10-22
DK2288358T3 (en) 2016-01-11
US20090292109A1 (en) 2009-11-26
EP2288358B1 (en) 2015-09-23
IL208376A (en) 2015-10-29
NZ588408A (en) 2012-05-25
EP2288358A4 (en) 2012-12-26
CN102065870A (zh) 2011-05-18
EP2288358A1 (en) 2011-03-02
MX2010011206A (es) 2010-11-12
CA2720048A1 (en) 2009-10-22
AU2009236653A1 (en) 2009-10-22
IL208376A0 (en) 2010-12-30
CN102065870B (zh) 2014-11-19
JP5631301B2 (ja) 2014-11-26

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: BIOGEN MA INC. (US)

B25I Requirement for requested change of headquarter

Owner name: BIOGEN MA INC. (US)

B25G Requested change of headquarter approved

Owner name: BIOGEN MA INC. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time
B350 Update of information on the portal [chapter 15.35 patent gazette]