DK0447585T4 - Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat - Google Patents

Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Info

Publication number
DK0447585T4
DK0447585T4 DK90105405T DK90105405T DK0447585T4 DK 0447585 T4 DK0447585 T4 DK 0447585T4 DK 90105405 T DK90105405 T DK 90105405T DK 90105405 T DK90105405 T DK 90105405T DK 0447585 T4 DK0447585 T4 DK 0447585T4
Authority
DK
Denmark
Prior art keywords
preparation
immunoglobulin
tolerant
intravenously
patients
Prior art date
Application number
DK90105405T
Other languages
English (en)
Other versions
DK0447585T3 (da
Inventor
Detlef Dr Dipl-Chem Piechaczek
Norbert Dr Dipl-Chem Kothe
Dieter Dr Dipl-Chem Rudnick
Herwald Dr Klein
Detlef Dr Dipl-Biol Rohm
Michael Dr Dipl-Chem Kloft
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8203787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0447585(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Publication of DK0447585T3 publication Critical patent/DK0447585T3/da
Application granted granted Critical
Publication of DK0447585T4 publication Critical patent/DK0447585T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
DK90105405T 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat DK0447585T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90105405A EP0447585B2 (de) 1990-03-22 1990-03-22 Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates

Publications (2)

Publication Number Publication Date
DK0447585T3 DK0447585T3 (da) 1995-05-29
DK0447585T4 true DK0447585T4 (da) 2003-09-01

Family

ID=8203787

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90105405T DK0447585T4 (da) 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Country Status (7)

Country Link
US (1) US5164487A (da)
EP (1) EP0447585B2 (da)
JP (1) JPH06107561A (da)
AT (1) ATE122054T1 (da)
DE (1) DE59009020D1 (da)
DK (1) DK0447585T4 (da)
ES (1) ES2074490T5 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
JP4685238B2 (ja) * 1998-06-09 2011-05-18 ツエー・エス・エル・ベーリング・アクチエンゲゼルシヤフト 静脈投与用免疫グロブリン及び他の免疫グロブリン生成物の製造法
DE19904407C2 (de) 1999-02-04 2001-09-20 Bayer Ag Vorrichtung zum Wechseln einer Düsenplatte eines Prillturmes und Verfahren zum automatisierten Wechsel
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
FR2824568B1 (fr) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
EP1786827A4 (en) * 2004-05-14 2008-10-29 Kirin Holdings Kk PROCESS FOR IMMUNOGLOBULINE CLEANING
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
FR2895263B1 (fr) 2005-12-26 2008-05-30 Lab Francais Du Fractionnement Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives
WO2008127305A2 (en) * 2006-11-01 2008-10-23 Biogen Idec Ma Inc. Method of isolating biomacromolecules using low ph and divalent cations
KR101226353B1 (ko) 2007-06-01 2013-01-24 에프. 호프만-라 로슈 아게 면역글로불린 정제
PT2271382E (pt) 2008-04-15 2013-05-07 Grifols Therapeutics Inc Ultrafiltração em dois andares/diafiltração
CA2720048A1 (en) * 2008-04-16 2009-10-22 Biogen Idec Ma Inc. Method of isolating biomacromolecules using polyalkylene glycol and transition metals
ES2716088T3 (es) 2010-02-04 2019-06-10 Csl Behring Ag Preparado de inmunoglobulina
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
US8772462B2 (en) 2010-05-26 2014-07-08 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) * 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
KR20150122650A (ko) * 2013-02-28 2015-11-02 에이전시 포 사이언스, 테크놀로지 앤드 리서치 상승된 전도도에서 비이온성 유기 폴리머들의 존재에서의 단백질 정제
SG11201505192RA (en) * 2013-02-28 2015-08-28 Agency Science Tech & Res Chromatographic purification of antibodies from chromatin-deficient cell culture harvests
DK3016976T3 (da) 2013-07-01 2020-12-07 Csl Behring Ag Proces
KR102356757B1 (ko) 2013-10-18 2022-02-03 노바셉 이큅먼트 솔루션즈 단백질 정제
WO2015166072A1 (en) 2014-04-30 2015-11-05 Novo Nordisk A/S Methods for the purification of proteins using caprylic acid
KR101657690B1 (ko) * 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 혈장 유래 b형 간염 사람 면역글로불린 제제의 제조방법
EP3275897A1 (en) 2016-07-27 2018-01-31 Biotest AG Process for preparing immunoglobulin compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916026A (en) * 1968-09-19 1975-10-28 Biotest Serum Institut Gmbh Method for the preparation of gamma-globulin suitable for intravenous use
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
EP0338229B1 (de) * 1988-04-19 1993-06-16 Biotest Pharma Gmbh Präparat mit Antikörperaktivität und breitem Wirkungsspektrum, daraus bestehende oder diese enthaltende Mittel und deren Verwendung zur Behandlung von bakteriell oder toxin-bedingten Erkrankungen und zur Bekämpfung von Protozoen
FR2632308B1 (fr) * 1988-06-07 1991-08-16 Fondation Nale Transfusion San Procede et installation de fractionnement en continu de proteines vegetales animales ou humaines
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process

Also Published As

Publication number Publication date
ES2074490T5 (es) 2004-02-16
DK0447585T3 (da) 1995-05-29
EP0447585B2 (de) 2003-05-07
ATE122054T1 (de) 1995-05-15
ES2074490T3 (es) 1995-09-16
US5164487A (en) 1992-11-17
EP0447585B1 (de) 1995-05-03
EP0447585A1 (de) 1991-09-25
JPH06107561A (ja) 1994-04-19
DE59009020D1 (de) 1995-06-08

Similar Documents

Publication Publication Date Title
DK0447585T3 (da) Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat
DE69328519D1 (de) Chondroitinase, Herstellungsverfahren und pharmazeutische Zusammensetzung
ES525361A0 (es) Procedimiento para preparar un medicamento seguro contra hepatitis que contiene la proteina llamada inactivador cl.
DE3650135D1 (de) Proteingewinnung.
SE8602877L (sv) Extraktionsforfarande for mjolkproteiner, produkter, anvendning av forfarandet och farmaceutiska kompositioner
GB9019919D0 (en) Purification of proteins
FR2487642B2 (fr) Procede de preparation de fractions proteiques par ultrafiltration et chromatographie d'exclusion et d'echange d'ions
ATE104987T1 (de) Verfahren zur anreicherung der blutgerinnungsfaktoren ii, vii, ix und x.
ES2068827T3 (es) Produccion de proteinas en forma activa.
PT71408A (de) Verfahren zur herstellung von 1-alkadien-2,4-yl-2-hidroxymethyl-3,4,5-trimydroxypiperidinen mit wirkung uber die kohlehydraten und/oder fettwechsel und von diesen verbindungen enthaltenden pharmazeutischen und/oder tierartzleichen praparaten
DK643389D0 (da) Endotelcellevaekstfaktor samt fremgangsmaade til oprensning deraf
SE7906273L (sv) Sett att framstella en gammaglobulinlosning
GB1369488A (en) Method of removing organic materials bacteria or viruses from aqueous solutions thereof
GB941019A (en) Improvements in and relating to the stability of anti-haemophilic globulin (factor viii)
FR2522479B1 (fr) Procede de traitement des matieres vegetales proteiques et glucidiques, dans une meme installation
EP0085220A3 (en) Method for purification of anterior pituitary hormones
ATE37873T1 (de) Verfahren zur herstellung optisch aktiver 1,4dihydropyridine.
SE7710201L (sv) Medel med antimalign verkan
DE69116582D1 (de) Verfahren zur Herstellung von rekombinantem Humaninterferon-beta in reiner Form
FR2573100B1 (fr) Autoclave de traitement de matiere par des liquides
JPS55115856A (en) Active polypeptide and its preparation
JPS57147056A (en) Method for analysis of amino acid
JPS5668648A (en) Novel antibiotic substance pa-4046-i and its preparation