DK0447585T3 - Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat - Google Patents

Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Info

Publication number
DK0447585T3
DK0447585T3 DK90105405.6T DK90105405T DK0447585T3 DK 0447585 T3 DK0447585 T3 DK 0447585T3 DK 90105405 T DK90105405 T DK 90105405T DK 0447585 T3 DK0447585 T3 DK 0447585T3
Authority
DK
Denmark
Prior art keywords
preparation
immunoglobulin
tolerant
intravenously
patients
Prior art date
Application number
DK90105405.6T
Other languages
English (en)
Other versions
DK0447585T4 (da
Inventor
Detlef Dr Dipl-Chem Piechaczek
Norbert Dr Dipl-Chem Kothe
Dieter Dr Dipl-Chem Rudnick
Herwald Dr Klein
Detlef Dr Dipl-Biol Rohm
Michael Dr Dipl-Chem Kloft
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8203787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0447585(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Publication of DK0447585T3 publication Critical patent/DK0447585T3/da
Application granted granted Critical
Publication of DK0447585T4 publication Critical patent/DK0447585T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK90105405T 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat DK0447585T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90105405A EP0447585B2 (de) 1990-03-22 1990-03-22 Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates

Publications (2)

Publication Number Publication Date
DK0447585T3 true DK0447585T3 (da) 1995-05-29
DK0447585T4 DK0447585T4 (da) 2003-09-01

Family

ID=8203787

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90105405T DK0447585T4 (da) 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Country Status (7)

Country Link
US (1) US5164487A (da)
EP (1) EP0447585B2 (da)
JP (1) JPH06107561A (da)
AT (1) ATE122054T1 (da)
DE (1) DE59009020D1 (da)
DK (1) DK0447585T4 (da)
ES (1) ES2074490T5 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
US5886154A (en) * 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
DK2270044T3 (da) * 1998-06-09 2015-01-26 Csl Behring Ag Flydende immunglobulin G (IgG) produkt
DE19904407C2 (de) * 1999-02-04 2001-09-20 Bayer Ag Vorrichtung zum Wechseln einer Düsenplatte eines Prillturmes und Verfahren zum automatisierten Wechsel
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
FR2824568B1 (fr) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
US20050272917A1 (en) * 2004-05-14 2005-12-08 Hematech, Llc Methods for immunoglobulin purification
TWI391399B (zh) * 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
FR2895263B1 (fr) 2005-12-26 2008-05-30 Lab Francais Du Fractionnement Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives
AU2007351548B2 (en) * 2006-11-01 2012-08-16 Biogen Ma Inc. Method of isolating biomacromolecules using low pH and divalent cations
JP5064558B2 (ja) 2007-06-01 2012-10-31 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリン精製
PL2271382T3 (pl) 2008-04-15 2013-08-30 Grifols Therapeutics Inc Dwuetapowa ultrafiltracja/diafiltracja
BRPI0911249A2 (pt) * 2008-04-16 2017-05-23 Biogen Idec Inc método de isolamento de biomacromoléculas usando polialquileno glicol e metais de transição
CA2788863C (en) 2010-02-04 2020-07-07 Reinhard Franz Bolli Immunoglobulin preparation
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
WO2011150284A2 (en) 2010-05-26 2011-12-01 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
FR2974301B1 (fr) 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) * 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
EP2961761B1 (en) * 2013-02-28 2018-09-12 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers at elevated conductivity
KR20150123796A (ko) 2013-02-28 2015-11-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 크로마틴 결핍 세포 배양 수확물로부터의 항체들의 크로마토그래프 정제
DK3016976T3 (da) 2013-07-01 2020-12-07 Csl Behring Ag Proces
KR102356757B1 (ko) 2013-10-18 2022-02-03 노바셉 이큅먼트 솔루션즈 단백질 정제
CN106459142B (zh) 2014-04-30 2021-07-13 诺和诺德股份有限公司 使用辛酸纯化蛋白质的方法
KR101657690B1 (ko) * 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 혈장 유래 b형 간염 사람 면역글로불린 제제의 제조방법
EP3275897A1 (en) 2016-07-27 2018-01-31 Biotest AG Process for preparing immunoglobulin compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916026A (en) * 1968-09-19 1975-10-28 Biotest Serum Institut Gmbh Method for the preparation of gamma-globulin suitable for intravenous use
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
DE58904683D1 (de) * 1988-04-19 1993-07-22 Biotest Pharma Gmbh Praeparat mit antikoerperaktivitaet und breitem wirkungsspektrum, daraus bestehende oder diese enthaltende mittel und deren verwendung zur behandlung von bakteriell oder toxin-bedingten erkrankungen und zur bekaempfung von protozoen.
FR2632308B1 (fr) * 1988-06-07 1991-08-16 Fondation Nale Transfusion San Procede et installation de fractionnement en continu de proteines vegetales animales ou humaines
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process

Also Published As

Publication number Publication date
EP0447585B2 (de) 2003-05-07
DK0447585T4 (da) 2003-09-01
US5164487A (en) 1992-11-17
EP0447585A1 (de) 1991-09-25
ES2074490T3 (es) 1995-09-16
ES2074490T5 (es) 2004-02-16
JPH06107561A (ja) 1994-04-19
DE59009020D1 (de) 1995-06-08
EP0447585B1 (de) 1995-05-03
ATE122054T1 (de) 1995-05-15

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