DK0447585T3 - Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat - Google Patents

Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Info

Publication number
DK0447585T3
DK0447585T3 DK90105405.6T DK90105405T DK0447585T3 DK 0447585 T3 DK0447585 T3 DK 0447585T3 DK 90105405 T DK90105405 T DK 90105405T DK 0447585 T3 DK0447585 T3 DK 0447585T3
Authority
DK
Denmark
Prior art keywords
preparation
immunoglobulin
tolerant
intravenously
patients
Prior art date
Application number
DK90105405.6T
Other languages
English (en)
Other versions
DK0447585T4 (da
Inventor
Detlef Dr Dipl-Chem Piechaczek
Norbert Dr Dipl-Chem Kothe
Dieter Dr Dipl-Chem Rudnick
Herwald Dr Klein
Detlef Dr Dipl-Biol Rohm
Michael Dr Dipl-Chem Kloft
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8203787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0447585(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Publication of DK0447585T3 publication Critical patent/DK0447585T3/da
Application granted granted Critical
Publication of DK0447585T4 publication Critical patent/DK0447585T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK90105405T 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat DK0447585T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90105405A EP0447585B2 (de) 1990-03-22 1990-03-22 Verfahren zur Herstellung eines intravenös verträglichen Immunglobulin-G-Präparates

Publications (2)

Publication Number Publication Date
DK0447585T3 true DK0447585T3 (da) 1995-05-29
DK0447585T4 DK0447585T4 (da) 2003-09-01

Family

ID=8203787

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90105405T DK0447585T4 (da) 1990-03-22 1990-03-22 Fremgangsmåde til fremstilling af et intravenøst tolerant immunglobulin-G-præparat

Country Status (7)

Country Link
US (1) US5164487A (da)
EP (1) EP0447585B2 (da)
JP (1) JPH06107561A (da)
AT (1) ATE122054T1 (da)
DE (1) DE59009020D1 (da)
DK (1) DK0447585T4 (da)
ES (1) ES2074490T5 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
DK2270044T3 (da) * 1998-06-09 2015-01-26 Csl Behring Ag Flydende immunglobulin G (IgG) produkt
DE19904407C2 (de) * 1999-02-04 2001-09-20 Bayer Ag Vorrichtung zum Wechseln einer Düsenplatte eines Prillturmes und Verfahren zum automatisierten Wechsel
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
FR2824568B1 (fr) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
EP1532983A1 (en) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulin preparations having increased stability
US20050272917A1 (en) * 2004-05-14 2005-12-08 Hematech, Llc Methods for immunoglobulin purification
TWI391399B (zh) 2005-05-25 2013-04-01 赫孚孟拉羅股份公司 測定溶離多肽之鹽濃度之方法
FR2895263B1 (fr) 2005-12-26 2008-05-30 Lab Francais Du Fractionnement Concentre d'immunoglobines g (lg) appauvri en anticorps anti-a et anti-b, et en igg polyreactives
TWI442965B (zh) * 2006-11-01 2014-07-01 Biogen Idec Inc 使用低ｐＨ及二價陽離子分離生物巨分子的方法
RU2009148891A (ru) 2007-06-01 2011-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) Очистка иммуноглобулина
PT2271382E (pt) 2008-04-15 2013-05-07 Grifols Therapeutics Inc Ultrafiltração em dois andares/diafiltração
CN102065870B (zh) * 2008-04-16 2014-11-19 比奥根艾迪克Ma公司 使用聚亚烷基二醇和过渡金属分离生物大分子的方法
US8546548B2 (en) 2009-05-27 2013-10-01 Baxter International Inc. Method to produce a highly concentrated immunoglobulin preparation for subcutaneous use
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
DK2531218T3 (da) 2010-02-04 2019-04-01 Csl Behring Ag Immunoglobulinpræparat
EP2361636A1 (en) 2010-02-26 2011-08-31 CSL Behring AG Immunoglobulin preparation and storage system for an immunoglobulin preparation
US8772462B2 (en) 2010-05-26 2014-07-08 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
FR2974301B1 (fr) * 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) * 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
WO2014133459A1 (en) * 2013-02-28 2014-09-04 Agency For Science, Technology And Research Chromatographic purification of antibodies from chromatin-deficient cell culture harvests
CN105008384A (zh) * 2013-02-28 2015-10-28 新加坡科技研究局 在高电导率下在非离子性有机聚合物的存在下的蛋白质纯化
JP6474798B2 (ja) 2013-07-01 2019-02-27 ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト 方法
WO2015056237A2 (en) 2013-10-18 2015-04-23 Universität Für Bodenkultur Wien Purification of proteins
ES2975172T1 (es) 2014-04-30 2024-07-03 Novo Nordisk As Métodos para la purificación de proteínas usando ácido caprílico
CN121371151A (zh) 2014-12-03 2026-01-23 瑞士杰特贝林生物制品有限公司 具有增加的稳定性的包含免疫球蛋白的药物产品
KR101657690B1 (ko) * 2015-06-05 2016-09-19 주식회사 녹십자홀딩스 혈장 유래 b형 간염 사람 면역글로불린 제제의 제조방법
EP3275897A1 (en) 2016-07-27 2018-01-31 Biotest AG Process for preparing immunoglobulin compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916026A (en) * 1968-09-19 1975-10-28 Biotest Serum Institut Gmbh Method for the preparation of gamma-globulin suitable for intravenous use
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
EP0338229B1 (de) * 1988-04-19 1993-06-16 Biotest Pharma Gmbh Präparat mit Antikörperaktivität und breitem Wirkungsspektrum, daraus bestehende oder diese enthaltende Mittel und deren Verwendung zur Behandlung von bakteriell oder toxin-bedingten Erkrankungen und zur Bekämpfung von Protozoen
FR2632308B1 (fr) * 1988-06-07 1991-08-16 Fondation Nale Transfusion San Procede et installation de fractionnement en continu de proteines vegetales animales ou humaines
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process

Also Published As

Publication number Publication date
DE59009020D1 (de) 1995-06-08
ATE122054T1 (de) 1995-05-15
JPH06107561A (ja) 1994-04-19
US5164487A (en) 1992-11-17
EP0447585B1 (de) 1995-05-03
EP0447585B2 (de) 2003-05-07
DK0447585T4 (da) 2003-09-01
ES2074490T5 (es) 2004-02-16
EP0447585A1 (de) 1991-09-25
ES2074490T3 (es) 1995-09-16

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