DE69733723D1 - 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung - Google Patents

6-o-Substituierte Ketoliden mit antibakteriellen Wirkung

Info

Publication number
DE69733723D1
DE69733723D1 DE69733723T DE69733723T DE69733723D1 DE 69733723 D1 DE69733723 D1 DE 69733723D1 DE 69733723 T DE69733723 T DE 69733723T DE 69733723 T DE69733723 T DE 69733723T DE 69733723 D1 DE69733723 D1 DE 69733723D1
Authority
DE
Germany
Prior art keywords
alkyl
substituted
heteroaryl
aryl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69733723T
Other languages
English (en)
Other versions
DE69733723T2 (de
Inventor
Yat Sun Or
Zhenkun Ma
Richard F Clark
Daniel T Chu
Jacob J Plattner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107953&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69733723(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/888,350 external-priority patent/US5866549A/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69733723D1 publication Critical patent/DE69733723D1/de
Publication of DE69733723T2 publication Critical patent/DE69733723T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69733723T 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung Expired - Lifetime DE69733723T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70777696A 1996-09-04 1996-09-04
US707776 1996-09-04
US08/888,350 US5866549A (en) 1996-09-04 1997-07-03 6-O-substituted ketolides having antibacterial activity
US888350 1997-07-03

Publications (2)

Publication Number Publication Date
DE69733723D1 true DE69733723D1 (de) 2005-08-18
DE69733723T2 DE69733723T2 (de) 2006-04-20

Family

ID=27107953

Family Applications (5)

Application Number Title Priority Date Filing Date
DE69733422T Expired - Lifetime DE69733422T2 (de) 1996-09-04 1997-09-02 6-0-substituierte ketoliden mit antibakteriellen wirkung
DE69733369T Expired - Lifetime DE69733369T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirking
DE69733370T Expired - Lifetime DE69733370T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
DE69733439T Expired - Lifetime DE69733439T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
DE69733723T Expired - Lifetime DE69733723T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung

Family Applications Before (4)

Application Number Title Priority Date Filing Date
DE69733422T Expired - Lifetime DE69733422T2 (de) 1996-09-04 1997-09-02 6-0-substituierte ketoliden mit antibakteriellen wirkung
DE69733369T Expired - Lifetime DE69733369T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirking
DE69733370T Expired - Lifetime DE69733370T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
DE69733439T Expired - Lifetime DE69733439T2 (de) 1996-09-04 1997-09-02 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung

Country Status (28)

Country Link
US (4) US6028181A (de)
EP (5) EP1291351B1 (de)
JP (1) JP4597274B2 (de)
KR (5) KR100523679B1 (de)
CN (4) CN100441591C (de)
AT (5) ATE296307T1 (de)
BG (1) BG63547B1 (de)
BR (1) BR9711661A (de)
CA (1) CA2263972C (de)
CZ (1) CZ300106B6 (de)
DE (5) DE69733422T2 (de)
DK (5) DK0929563T3 (de)
ES (5) ES2242811T3 (de)
HK (1) HK1021537A1 (de)
HR (5) HRP970473B1 (de)
HU (1) HU230166B1 (de)
ID (1) ID19406A (de)
IL (1) IL128681A0 (de)
NO (1) NO314230B1 (de)
NZ (1) NZ334274A (de)
PL (1) PL188173B1 (de)
PT (5) PT1291352E (de)
RO (1) RO121473B1 (de)
RU (1) RU2192427C2 (de)
SI (1) SI20023B (de)
SK (5) SK285534B6 (de)
TR (1) TR199901127T2 (de)
WO (1) WO1998009978A1 (de)

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UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
ES2199524T3 (es) 1998-04-24 2004-02-16 Pfizer Products Inc. Derivados 9a,11b-deshidro de 9-oxima-3-ceto-6-o-metileritromicina.
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4043191B2 (ja) 1998-11-03 2008-02-06 ファイザー・プロダクツ・インク 新規なマクロライド抗生物質
SK13162001A3 (sk) * 1999-03-15 2001-12-03 Abbott Laboratories 6-o-substituované makrolidy majúce antibakteriálnu aktivitu
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
ATE340183T1 (de) 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
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ATE250076T1 (de) * 1999-06-07 2003-10-15 Abbott Lab 6-o-carbamat ketolide derivate
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
EP1101769A3 (de) 1999-11-18 2001-10-24 Pfizer Products Inc. Stickstoff-enthaltend Erythromycin-Derivate
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ES2242812T3 (es) 2005-11-16
CN100441591C (zh) 2008-12-10
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DE69733439D1 (de) 2005-07-07
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