DE60020613T2 - (S,S)-Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen - Google Patents

(S,S)-Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen Download PDF

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Publication number
DE60020613T2
DE60020613T2 DE60020613T DE60020613T DE60020613T2 DE 60020613 T2 DE60020613 T2 DE 60020613T2 DE 60020613 T DE60020613 T DE 60020613T DE 60020613 T DE60020613 T DE 60020613T DE 60020613 T2 DE60020613 T2 DE 60020613T2
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Prior art keywords
reboxetine
norepinephrine
optically pure
reuptake
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60020613T
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German (de)
English (en)
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DE60020613D1 (de
Inventor
Saeeduddin Portage Ahmed
Lars Martinsville Birgerson
Pasquale Annandale Cetera
Robert Clyde Mattawan Marshall
Robert Kalamazoo McArthur
Duncan P. Kalamazoo Taylor
Erik H.F. Portage Wong
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Pharmacia and Upjohn Co LLC
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Pharmacia and Upjohn Co LLC
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Application filed by Pharmacia and Upjohn Co LLC filed Critical Pharmacia and Upjohn Co LLC
Publication of DE60020613D1 publication Critical patent/DE60020613D1/de
Application granted granted Critical
Publication of DE60020613T2 publication Critical patent/DE60020613T2/de
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
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  • Hospice & Palliative Care (AREA)
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  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
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  • Anesthesiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60020613T 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen Expired - Lifetime DE60020613T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US14196899P 1999-07-01 1999-07-01
US141968P 1999-07-01
US14413199P 1999-07-16 1999-07-16
US144131P 1999-07-16
US15825699P 1999-10-06 1999-10-06
US158256P 1999-10-06
US17038199P 1999-12-13 1999-12-13
US170381P 1999-12-13

Publications (2)

Publication Number Publication Date
DE60020613D1 DE60020613D1 (de) 2005-07-07
DE60020613T2 true DE60020613T2 (de) 2006-03-16

Family

ID=27495506

Family Applications (9)

Application Number Title Priority Date Filing Date
DE60020613T Expired - Lifetime DE60020613T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen
DE60022692T Expired - Lifetime DE60022692T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen
DE60023043T Expired - Lifetime DE60023043T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Inkontinenz
DE60019473T Expired - Lifetime DE60019473T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von peripheren Neuropathien
DE60022917T Expired - Fee Related DE60022917T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von Migränekopfschmerzen
DE60026627T Expired - Fee Related DE60026627T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen
DE60026704T Expired - Lifetime DE60026704T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetine zur Behandlung chronischer Schmerzen
DE60022916T Expired - Fee Related DE60022916T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von peripheren Neuropathien
DE60035232T Expired - Lifetime DE60035232T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von chronischem Müdigkeits-Syndrom

Family Applications After (8)

Application Number Title Priority Date Filing Date
DE60022692T Expired - Lifetime DE60022692T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen
DE60023043T Expired - Lifetime DE60023043T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von Inkontinenz
DE60019473T Expired - Lifetime DE60019473T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von peripheren Neuropathien
DE60022917T Expired - Fee Related DE60022917T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von Migränekopfschmerzen
DE60026627T Expired - Fee Related DE60026627T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von Fibromyalgie und anderen somatoformen Störungen
DE60026704T Expired - Lifetime DE60026704T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetine zur Behandlung chronischer Schmerzen
DE60022916T Expired - Fee Related DE60022916T2 (de) 1999-07-01 2000-06-22 Reboxetin zur Behandlung von peripheren Neuropathien
DE60035232T Expired - Lifetime DE60035232T2 (de) 1999-07-01 2000-06-22 (S,S)-Reboxetin zur Behandlung von chronischem Müdigkeits-Syndrom

Country Status (30)

Country Link
US (18) US6465458B1 (enExample)
EP (3) EP2090312A1 (enExample)
JP (3) JP2003503450A (enExample)
KR (5) KR20090087135A (enExample)
CN (5) CN1205935C (enExample)
AR (1) AR035158A1 (enExample)
AT (9) ATE319453T1 (enExample)
AU (2) AU771258B2 (enExample)
BR (1) BR0012136A (enExample)
CA (2) CA2375908C (enExample)
CL (3) CL2008002866A1 (enExample)
CO (1) CO5190662A1 (enExample)
CZ (1) CZ299847B6 (enExample)
DE (9) DE60020613T2 (enExample)
DK (4) DK1459749T3 (enExample)
EA (6) EA006652B1 (enExample)
ES (9) ES2247572T3 (enExample)
GE (1) GEP20094798B (enExample)
HU (1) HUP0201623A3 (enExample)
IL (3) IL147246A0 (enExample)
MX (1) MXPA02000562A (enExample)
MY (1) MY137348A (enExample)
NO (4) NO20016406L (enExample)
NZ (2) NZ533243A (enExample)
PE (1) PE20010684A1 (enExample)
PL (1) PL196996B1 (enExample)
PT (5) PT1632234E (enExample)
SK (5) SK286669B6 (enExample)
TW (9) TWI298255B (enExample)
WO (1) WO2001001973A2 (enExample)

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