YU37602A - Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns - Google Patents

Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns

Info

Publication number
YU37602A
YU37602A YU37602A YUP37602A YU37602A YU 37602 A YU37602 A YU 37602A YU 37602 A YU37602 A YU 37602A YU P37602 A YUP37602 A YU P37602A YU 37602 A YU37602 A YU 37602A
Authority
YU
Yugoslavia
Prior art keywords
treatment
combination
cns disorders
pyrrolidineacetamide
derivative alone
Prior art date
Application number
YU37602A
Other languages
English (en)
Inventor
Yves Lamberty
Alain Matagne
Henrik Klitgaard
Tony Waegemans
Original Assignee
Ucb S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb S.A. filed Critical Ucb S.A.
Publication of YU37602A publication Critical patent/YU37602A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Upotreba (S)-(-)α-alfa-etil-2-okso-1-pirolidinacetamida za proizvodnju leka za tretman odredjenih bolesti i novih farmaceutskih preparata koji sadrže (S)-(-)-alfa-etil-2-okso-1-pirolidinacetamid.[A use of (S)-(-)-α -ethyl-2-oxo-1-pyrrolidineacetamide for the manufacture of a medicament for treatment of particular diseases and new pharmaceutical compositions comprising (S)-(-)-α-ethyl-2-oxo-1-pyrrolidineacetamide.
YU37602A 1999-12-01 2000-11-27 Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns YU37602A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99123803 1999-12-01
EP99124269 1999-12-01

Publications (1)

Publication Number Publication Date
YU37602A true YU37602A (sh) 2005-07-19

Family

ID=26153183

Family Applications (1)

Application Number Title Priority Date Filing Date
YU37602A YU37602A (sh) 1999-12-01 2000-11-27 Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns

Country Status (32)

Country Link
US (2) US6903130B1 (sh)
EP (4) EP1600168A3 (sh)
JP (2) JP4249415B2 (sh)
KR (1) KR20030016205A (sh)
CN (1) CN100525761C (sh)
AR (1) AR026610A1 (sh)
AT (1) ATE361751T1 (sh)
AU (1) AU773418B2 (sh)
BG (1) BG106708A (sh)
BR (1) BR0015974A (sh)
CA (2) CA2392879C (sh)
CO (1) CO5261590A1 (sh)
CZ (1) CZ20021904A3 (sh)
DE (1) DE60034815T2 (sh)
EE (1) EE200200274A (sh)
ES (1) ES2287039T3 (sh)
HK (1) HK1052647B (sh)
HU (1) HUP0204023A3 (sh)
IL (2) IL149530A0 (sh)
IS (1) IS6377A (sh)
MX (1) MXPA02005275A (sh)
MY (1) MY127980A (sh)
NO (1) NO20022585L (sh)
NZ (1) NZ518901A (sh)
PL (1) PL357472A1 (sh)
RO (1) RO121085B1 (sh)
RU (1) RU2261093C2 (sh)
SA (1) SA01210655B1 (sh)
SK (1) SK7492002A3 (sh)
TW (1) TWI238062B (sh)
WO (1) WO2001039779A1 (sh)
YU (1) YU37602A (sh)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004297D0 (en) 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
US6756379B2 (en) 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
US7683071B2 (en) 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
US7608636B2 (en) 2000-12-28 2009-10-27 Hamilton Pharmaceuticals, Inc. Medicines for treatment and prevention of neurogenic pain
EP1379236A4 (en) * 2001-02-23 2009-01-21 Ucb Sa TREATMENT OF TICS, TREMORS AND RELATED DISORDERS
EP1406872B1 (en) * 2001-06-20 2007-12-19 Merck & Co., Inc. Dipeptidyl peptidase inhibitors for the treatment of diabetes
US7544681B2 (en) 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
WO2003030899A2 (en) * 2001-10-08 2003-04-17 Ucb, S.A. Use of 2-oxo-1-pyrrolidine derivatives for the treatment of dyskinesia and movement disorders
WO2003094913A1 (en) * 2002-05-14 2003-11-20 Ucb, S.A. Use of 2-oxo-1-pyrrolidone derivatives for the preparation of a drug
US20070135514A1 (en) 2002-12-03 2007-06-14 Berkley Lynch Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases
CN101569626B (zh) * 2002-12-11 2012-02-08 塔罗制药工业有限公司 使用巴比土酸衍生物治疗运动障碍的方法
WO2004083180A1 (en) * 2003-03-18 2004-09-30 Hetero Drugs Limited Novel crystalline forms of levetiracetam
GB0307860D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
EP1637161A4 (en) * 2003-04-22 2007-06-27 Astellas Pharma Inc MEANS FOR THE TREATMENT OF NEURODEGENERATIVE ILLNESSES OF THE BRAIN WITH PPAR [delta] AGONIST
EP1685832B1 (en) * 2003-10-03 2011-04-06 Ono Pharmaceutical Co., Ltd. Nerve regeneration promoters
JP2008534522A (ja) 2005-03-30 2008-08-28 ジェンファーム インク 医薬組成物のための複合ステップ製造方法
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
WO2006127300A1 (en) * 2005-05-24 2006-11-30 Cambrex Charles City, Inc. SYNTHESIS OF (S)-α-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE
US8802142B2 (en) 2005-07-26 2014-08-12 Ucb Pharma, S.A. Pharmaceutical compositions comprising levetiracetam and process for their preparation
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
EP1754476A1 (en) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia
FR2890563B1 (fr) * 2005-09-09 2007-10-19 Servier Lab Nouvelle association entre l'agomelatine et un agent thymoregulateur et les compositions pharmaceutiques qui la contiennent
US20070172521A1 (en) * 2006-01-24 2007-07-26 Julia Hrakovsky Levetiracetam formulations and methods for their manufacture
EA027836B1 (ru) * 2006-06-15 2017-09-29 ЮСиБи ФАРМА ГМБХ Фармацевтическая комбинация для профилактики, облегчения и/или лечения приступов эпилепсии и ее применение
KR20090048462A (ko) * 2006-07-17 2009-05-13 라모트 앳 텔-아비브 유니버시티 리미티드 통증완화용 gaba 접합체
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
AU2007346591A1 (en) 2007-02-07 2008-08-14 Gosforth Centre (Holdings) Pty Ltd Treatment of ADHD
ITMI20070770A1 (it) * 2007-04-16 2008-10-17 Brane Discovery S R L Impiego di dimiracetam nel trattamento del dolore cronico
AU2012201853B2 (en) * 2007-04-16 2013-06-27 Neurotune Ag Use of dimiracetam in the treatment of chronic pain
WO2009101616A1 (en) 2008-02-11 2009-08-20 Ramot At Tel Aviv University Ltd. Novel conjugates for treating neurodegenerative diseases and disorders
AU2009279372A1 (en) 2008-08-06 2010-02-11 Gosforth Centre (Holdings) Pty Ltd Compositions and methods for treating psychiatric disorders
ES2637497T3 (es) 2008-10-16 2017-10-13 The Johns Hopkins University Procedimientos y composiciones para la mejora de la función cognitiva
PL389364A1 (pl) * 2009-10-23 2011-04-26 Uniwersytet Jagielloński Nowe zastosowanie pochodnych 2-pirolidonu
AU2011219529A1 (en) 2010-02-24 2012-08-30 Bar-Ilan University Crystalline forms of the tri-mesylate salt of perphenazine-GABA and process of producing the same
WO2011126733A2 (en) * 2010-03-28 2011-10-13 Children's Medical Center Corporation Combination therapies: inhibitors of gaba transaminase and nkcc1
US8916610B2 (en) 2010-09-22 2014-12-23 Ramot At Tel-Aviv University Ltd. Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same
AU2018208662B2 (en) * 2012-11-14 2020-07-23 The Johns Hopkins University Methods and Compositions for Treating Schizophrenia
US20140206667A1 (en) * 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
ES2881081T3 (es) 2013-03-15 2021-11-26 Agenebio Inc Procedimientos y composiciones para mejorar la función cognitiva
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
KR101690175B1 (ko) * 2013-07-02 2016-12-27 경희대학교 산학협력단 고본 추출물을 유효성분으로 포함하는 불면증의 예방 또는 치료용 약학적 조성물
RU2538724C1 (ru) * 2013-12-19 2015-01-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства Способ лечения эпилепсии
IL279202B2 (en) 2014-01-21 2023-09-01 Janssen Pharmaceutica Nv Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use
PL3431106T3 (pl) * 2014-01-21 2021-06-28 Janssen Pharmaceutica Nv Kombinacje zawierające pozytywne modulatory allosteryczne metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
RU2563124C1 (ru) * 2014-04-28 2015-09-20 Федеральное государственное бюджетное учреждение "Федеральный медицинский исследовательский центр психиатрии и наркологии имени В.П. Сербского" Министерства здравоохранения Российской Федерации (ФГБУ "ФМИЦПН им. В.П. Сербского" Минздрава России) Способ диагностики шизофрении
MX2017014774A (es) 2015-05-22 2018-02-15 Agenebio Inc Composiciones farmaceuticas de levetiracetam de liberacion extendida.
CA3040482A1 (en) * 2016-10-14 2018-04-19 Scott P. Falci Treating neuropathic pain in spinal cord injured individuals
PL244071B1 (pl) * 2019-01-07 2023-11-27 Univ Jagiellonski Pochodne (2,5-dioksopirolidyn-1-ylo)(fenylo)-acetamidu i ich zastosowanie do leczenia chorób o podłożu neurologicznym

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412357D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
GB8827389D0 (en) 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide
EP0408782A1 (en) 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
GB9319732D0 (en) 1993-09-24 1993-11-10 Ucb Sa Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
CN1131855C (zh) 1997-12-16 2003-12-24 沃尼尔·朗伯公司 1-取代-1-氨基甲基-环烷衍生物(=加巴喷丁类似物)、其制备及其在治疗神经病方面的用途
CA2309354A1 (en) 1998-01-23 1999-07-29 Leslie Magnus-Miller Gabapentin and its derivatives for the treatment of muscular and skeletal pain
DE19820381B4 (de) * 1998-05-07 2007-01-25 Trw Fahrwerksysteme Gmbh & Co Kg Verfahren zur Beeinflussung der Ventilkennlinie
WO2000037616A1 (en) * 1998-12-23 2000-06-29 Cytoscan Sciences L.L.C. Compounds, methods of screening and methods of treatment for central and peripheral nervous system disorders
US6495601B1 (en) 1998-12-23 2002-12-17 Cytoscan Sciences Llc Methods and compositions for treating conditions of the central and peripheral nervous systems using non-synaptic mechanisms
AU771258B2 (en) * 1999-07-01 2004-03-18 Pharmacia & Upjohn Company Highly selective norepinephrine reuptake inhibitors and methods of using the same
AU2003225813A1 (en) * 2002-03-18 2003-10-08 Roger K. Cady Preemptive prophylaxis of migraine
US20040116506A1 (en) * 2002-06-20 2004-06-17 Krusz John Claude Use of levetiracetam for treating or preventing acute headaches
US20070135514A1 (en) * 2002-12-03 2007-06-14 Berkley Lynch Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases

Also Published As

Publication number Publication date
EP1244456A1 (en) 2002-10-02
EP1600167A3 (en) 2009-09-30
EP1600168A2 (en) 2005-11-30
EP1600168A3 (en) 2009-09-23
EP1244456B1 (en) 2007-05-09
US20050187205A1 (en) 2005-08-25
CN1402637A (zh) 2003-03-12
US6903130B1 (en) 2005-06-07
WO2001039779A1 (en) 2001-06-07
DE60034815T2 (de) 2008-01-31
AU1524101A (en) 2001-06-12
HK1052647B (zh) 2010-05-20
JP2003515564A (ja) 2003-05-07
KR20030016205A (ko) 2003-02-26
ES2287039T3 (es) 2007-12-16
PL357472A1 (en) 2004-07-26
EP1600169A2 (en) 2005-11-30
SA01210655B1 (ar) 2006-10-29
HUP0204023A3 (en) 2005-03-29
ATE361751T1 (de) 2007-06-15
AR026610A1 (es) 2003-02-19
AU773418B2 (en) 2004-05-27
JP4249415B2 (ja) 2009-04-02
HK1052647A1 (en) 2003-09-26
BG106708A (bg) 2003-02-28
TWI238062B (en) 2005-08-21
IL149530A0 (en) 2002-11-10
JP2008056697A (ja) 2008-03-13
NZ518901A (en) 2004-08-27
RU2002117279A (ru) 2004-02-27
RU2261093C2 (ru) 2005-09-27
IS6377A (is) 2002-05-10
EP1600167A2 (en) 2005-11-30
CA2392879A1 (en) 2001-06-07
RO121085B1 (ro) 2006-12-29
DE60034815D1 (de) 2007-06-21
CA2475026A1 (en) 2001-06-07
HUP0204023A2 (hu) 2003-03-28
IL149530A (en) 2007-07-04
EP1600169A3 (en) 2009-09-23
EE200200274A (et) 2003-06-16
NO20022585D0 (no) 2002-05-31
SK7492002A3 (en) 2003-02-04
NO20022585L (no) 2002-07-25
MY127980A (en) 2007-01-31
BR0015974A (pt) 2002-07-23
MXPA02005275A (es) 2003-02-17
CN100525761C (zh) 2009-08-12
CA2392879C (en) 2005-03-29
CO5261590A1 (es) 2003-03-31
CZ20021904A3 (cs) 2002-11-13

Similar Documents

Publication Publication Date Title
YU37602A (sh) Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns
IL195723A (en) Use of p53 inhibitors for the preparation of medicament
TW200505483A (en) New medicament compositions based on anticholinergically-effective compounds and β-mimetics
HUP0400529A3 (en) Use of chlorpromazine and pentamidine for preparation of pharmaceutical compositions for the treatment of neoplastic disorders
IL157656A (en) Metalloproteinase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the treatment of diseases mediated by metalloproteinase enzymes
HUP0301815A3 (en) Mono and disaccharide-based pharmaceutical composition for infections and other diseases and prophylactic and therapeutic treatment
AU2002225772A1 (en) Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
HK1076052A1 (en) Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
HUP0103654A2 (hu) Szmilagenin és/vagy anzurogenin-D alkalmazása Alzheimer-kór kezelésére szolgáló gyógyszerkészítmény előállítására
IL127943A (en) Pharmaceutical and cosmetic compositions for the treatment of skin disorders
IL150289A0 (en) Drug combination for the treatment of depression and related disorders comprising mirtazapine
IL115589A0 (en) Use of cck-b antagonists in pharmaceutical compositions
IL143985A0 (en) New use of melagatran
AU7862401A (en) Pharmaceutical compostion comprising trkaig2 for use in the prevention and/or treatment of cancer
BG104179A (en) Phanquinon administration for the treatment of the alzheimer's disease
BG108452A (en) Tablet comprising cetirizine and pseudoephedrine
HUP0300402A3 (en) Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain and pharmaceutical compositions containing them
IL147188A (en) Use of il6ril6 chimera in the manufacture of a remedy for neurological diseases
HUP0301553A3 (en) Pharmaceutical compositions and their use for treating neurological disorders
MXPA02011533A (es) Nuevas formulaciones de alfa-2,4-disulfofenil-n-terc-butilnitrona.
WO2001028535A3 (en) Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate
RS60604A (en) Carboxamidine derivatives and their use in the treatment of vascular diseases
HK1075654A1 (en) Hyperforin derivatives, the use thereof and formulations containing them
CA2260863A1 (en) Treatment of psychotic disorders
WO2000061125A3 (fr) L'osanetant dans le traitement des troubles de l'humeur