IL147188A - Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases - Google Patents

Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases

Info

Publication number
IL147188A
IL147188A IL147188A IL14718801A IL147188A IL 147188 A IL147188 A IL 147188A IL 147188 A IL147188 A IL 147188A IL 14718801 A IL14718801 A IL 14718801A IL 147188 A IL147188 A IL 147188A
Authority
IL
Israel
Prior art keywords
medicament
manufacture
neurological diseases
il6ril6 chimera
il6ril6
Prior art date
Application number
IL147188A
Other languages
Hebrew (he)
Original Assignee
Yeda Res & Dev
Merck Serono Sa
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, Merck Serono Sa, Applied Research Systems filed Critical Yeda Res & Dev
Priority to IL147188A priority Critical patent/IL147188A/en
Publication of IL147188A publication Critical patent/IL147188A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to the use of IL6RIL6 chimera in the treatment and prevention of neurological diseases and disorders.
IL147188A 1999-06-21 2001-12-19 Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases IL147188A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL147188A IL147188A (en) 1999-06-21 2001-12-19 Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL13058699A IL130586A0 (en) 1999-06-21 1999-06-21 IL6RIL6 chimera for the treatment of demyelinating diseases
PCT/IL2000/000363 WO2000078331A2 (en) 1999-06-21 2000-06-21 Il6ril6 chimera for the treatment of neurodegenerative diseases
IL147188A IL147188A (en) 1999-06-21 2001-12-19 Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases

Publications (1)

Publication Number Publication Date
IL147188A true IL147188A (en) 2015-09-24

Family

ID=11072949

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13058699A IL130586A0 (en) 1999-06-21 1999-06-21 IL6RIL6 chimera for the treatment of demyelinating diseases
IL147188A IL147188A (en) 1999-06-21 2001-12-19 Use of il6ril6 chimera for the manufacture of a medicament for neurological diseases

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL13058699A IL130586A0 (en) 1999-06-21 1999-06-21 IL6RIL6 chimera for the treatment of demyelinating diseases

Country Status (20)

Country Link
US (1) US7201896B1 (en)
EP (1) EP1185293B1 (en)
JP (1) JP4846148B2 (en)
KR (1) KR100678290B1 (en)
CN (1) CN1164328C (en)
AT (1) ATE306280T1 (en)
AU (1) AU778662B2 (en)
BR (1) BR0011363A (en)
CA (1) CA2374997C (en)
DE (1) DE60023139T2 (en)
DK (1) DK1185293T3 (en)
EA (1) EA004626B1 (en)
EE (1) EE05559B1 (en)
ES (1) ES2250140T3 (en)
IL (2) IL130586A0 (en)
MX (1) MXPA02000116A (en)
NO (1) NO329028B1 (en)
UA (1) UA76695C2 (en)
WO (1) WO2000078331A2 (en)
ZA (1) ZA200109488B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2262680T3 (en) * 2000-09-14 2006-12-01 Ares Trading S.A. USE OF A CHIMERA IL-6R / IL-6 IN HUNTINGTON'S DISEASE.
DE10107737A1 (en) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Use of a conjugate of IL-6 and an IL-6 receptor for tumor therapy
JP4594588B2 (en) * 2001-04-10 2010-12-08 ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニヴァーシティ Therapeutic and diagnostic uses of antibody-specific profiles
IL147412A0 (en) * 2001-12-31 2002-08-14 Yeda Res & Dev The use of il6r/il6 chimera in nerve cell regeneration
US8617887B2 (en) 2003-06-12 2013-12-31 Yeda Research And Development Co. Ltd Method of generating oligodendrocytes from neurosphere cells
US20070071727A1 (en) * 2003-11-14 2007-03-29 Olsson Mats J Melanocytes in therapy of neurodegenerative diseases
IL161672A0 (en) 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
IL163856A0 (en) * 2004-09-01 2005-12-18 Applied Research Systems Use of IL-6 in vascular complications
CN108778121A (en) * 2016-02-12 2018-11-09 Als治疗发展研究所 ALS disease progressions are assessed based on dynamics data
US11207354B2 (en) 2016-09-23 2021-12-28 Osaka University Schwann cell differentiation promoting agent and a peripheral nerve regeneration promoting agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
JPH1148413A (en) 1997-08-06 1999-02-23 Dainippon Printing Co Ltd Formaldehyde capturing wallpaper and method for producing the same
JP4859153B2 (en) * 1999-02-25 2012-01-25 東ソー株式会社 Novel neuronal cell differentiation promoter

Also Published As

Publication number Publication date
ZA200109488B (en) 2002-11-18
CA2374997A1 (en) 2000-12-28
KR20020013901A (en) 2002-02-21
EP1185293B1 (en) 2005-10-12
EP1185293A2 (en) 2002-03-13
CN1364088A (en) 2002-08-14
WO2000078331A2 (en) 2000-12-28
CN1164328C (en) 2004-09-01
BR0011363A (en) 2002-02-26
NO329028B1 (en) 2010-08-02
NO20015673L (en) 2001-12-17
NO20015673D0 (en) 2001-11-20
KR100678290B1 (en) 2007-02-05
WO2000078331A3 (en) 2001-07-05
US7201896B1 (en) 2007-04-10
EE05559B1 (en) 2012-08-15
DE60023139D1 (en) 2006-02-23
AU778662B2 (en) 2004-12-16
AU5423100A (en) 2001-01-09
HK1047549A1 (en) 2003-02-28
EE200100689A (en) 2003-02-17
IL130586A0 (en) 2000-06-01
UA76695C2 (en) 2006-09-15
ATE306280T1 (en) 2005-10-15
MXPA02000116A (en) 2003-07-21
DK1185293T3 (en) 2005-12-27
JP4846148B2 (en) 2011-12-28
DE60023139T2 (en) 2006-05-04
CA2374997C (en) 2010-04-13
ES2250140T3 (en) 2006-04-16
EA200200063A1 (en) 2002-06-27
JP2003502382A (en) 2003-01-21
EA004626B1 (en) 2004-06-24

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees