WO2001028535A3 - Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate - Google Patents

Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate Download PDF

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Publication number
WO2001028535A3
WO2001028535A3 PCT/EP2000/010306 EP0010306W WO0128535A3 WO 2001028535 A3 WO2001028535 A3 WO 2001028535A3 EP 0010306 W EP0010306 W EP 0010306W WO 0128535 A3 WO0128535 A3 WO 0128535A3
Authority
WO
WIPO (PCT)
Prior art keywords
salmeterol
combination
pharmaceutical formulations
fluticasone propionate
formulations
Prior art date
Application number
PCT/EP2000/010306
Other languages
French (fr)
Other versions
WO2001028535A2 (en
Inventor
Anthony J Taylor
David A Wyatt
Original Assignee
Glaxo Group Ltd
Anthony J Taylor
David A Wyatt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Anthony J Taylor, David A Wyatt filed Critical Glaxo Group Ltd
Priority to AU13858/01A priority Critical patent/AU1385801A/en
Publication of WO2001028535A2 publication Critical patent/WO2001028535A2/en
Publication of WO2001028535A3 publication Critical patent/WO2001028535A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention is concerned with pharmaceutical formulations comprising a combination of S-salmeterol and fluticasone propionate and the use of such formulations in medicine, particularly in the prophylaxis and treatment of respiratory diseases.
PCT/EP2000/010306 1999-10-21 2000-10-19 Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate WO2001028535A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU13858/01A AU1385801A (en) 1999-10-21 2000-10-19 Pharmaceutical formulations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9924992.2A GB9924992D0 (en) 1999-10-21 1999-10-21 Pharmaceutical aerosol formulations
GB9924992.2 1999-10-21

Publications (2)

Publication Number Publication Date
WO2001028535A2 WO2001028535A2 (en) 2001-04-26
WO2001028535A3 true WO2001028535A3 (en) 2002-01-10

Family

ID=10863173

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2000/010306 WO2001028535A2 (en) 1999-10-21 2000-10-19 Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate
PCT/EP2000/010305 WO2001028514A1 (en) 1999-10-21 2000-10-19 Pharmaceutical aerosol formulations comprising s-salmeterol

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/010305 WO2001028514A1 (en) 1999-10-21 2000-10-19 Pharmaceutical aerosol formulations comprising s-salmeterol

Country Status (3)

Country Link
AU (2) AU1141101A (en)
GB (1) GB9924992D0 (en)
WO (2) WO2001028535A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
US9198885B2 (en) 2005-07-14 2015-12-01 Neothetics, Inc. Lipolytic methods for regional adiposity comprising salmeterol or formoterol
US9597531B2 (en) 2010-11-24 2017-03-21 Neothetics, Inc. Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030516A1 (en) * 2000-08-31 2003-08-20 Glaxo Group Ltd USE OF A COMBINATION OF SALMETEROL AND FLUTICASONA
GB0021927D0 (en) * 2000-09-07 2000-10-25 Glaxo Group Ltd Use of pharmaceutical combination
GB0106031D0 (en) * 2001-03-12 2001-05-02 Glaxo Group Ltd Use
GB0124523D0 (en) * 2001-10-12 2001-12-05 Glaxo Group Ltd Pharmaceutical combination
AU2004241746A1 (en) * 2003-05-22 2004-12-02 Nycomed Gmbh Salmeterol and ciclesonide combination
TR201000685A2 (en) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Pharmaceutical preparations containing salmeterol and fluticasone.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011743A1 (en) * 1991-12-12 1993-06-24 Glaxo Group Limited Medicaments
WO1996032150A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for salmeterol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6254882B1 (en) * 1997-09-16 2001-07-03 Sepracor Inc. Methods and compositions for treating pulmonary disorders using optically pure (S)—salmeterol

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011743A1 (en) * 1991-12-12 1993-06-24 Glaxo Group Limited Medicaments
WO1996032150A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for salmeterol

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9198885B2 (en) 2005-07-14 2015-12-01 Neothetics, Inc. Lipolytic methods for regional adiposity comprising salmeterol or formoterol
US9370498B2 (en) 2005-07-14 2016-06-21 Neothetics, Inc. Methods of using lipolytic formulations for regional adipose tissue treatment
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
US9597531B2 (en) 2010-11-24 2017-03-21 Neothetics, Inc. Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging

Also Published As

Publication number Publication date
AU1141101A (en) 2001-04-30
GB9924992D0 (en) 1999-12-22
WO2001028514A1 (en) 2001-04-26
AU1385801A (en) 2001-04-30
WO2001028535A2 (en) 2001-04-26

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