KR20090087135A - 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 - Google Patents
고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 Download PDFInfo
- Publication number
- KR20090087135A KR20090087135A KR1020097015714A KR20097015714A KR20090087135A KR 20090087135 A KR20090087135 A KR 20090087135A KR 1020097015714 A KR1020097015714 A KR 1020097015714A KR 20097015714 A KR20097015714 A KR 20097015714A KR 20090087135 A KR20090087135 A KR 20090087135A
- Authority
- KR
- South Korea
- Prior art keywords
- reboxetine
- disorders
- norepinephrine
- reuptake
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14196899P | 1999-07-01 | 1999-07-01 | |
| US60/141,968 | 1999-07-01 | ||
| US14413199P | 1999-07-16 | 1999-07-16 | |
| US60/144,131 | 1999-07-16 | ||
| US15825699P | 1999-10-06 | 1999-10-06 | |
| US60/158,256 | 1999-10-06 | ||
| US17038199P | 1999-12-13 | 1999-12-13 | |
| US60/170,381 | 1999-12-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020067017835A Division KR100935277B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20090087135A true KR20090087135A (ko) | 2009-08-14 |
Family
ID=27495506
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097015714A Ceased KR20090087135A (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020017016963A Expired - Fee Related KR100704319B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020057009371A Expired - Fee Related KR100717660B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020097015713A Expired - Fee Related KR100948757B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020067017835A Expired - Fee Related KR100935277B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020017016963A Expired - Fee Related KR100704319B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020057009371A Expired - Fee Related KR100717660B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020097015713A Expired - Fee Related KR100948757B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
| KR1020067017835A Expired - Fee Related KR100935277B1 (ko) | 1999-07-01 | 2000-06-22 | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 |
Country Status (30)
| Country | Link |
|---|---|
| US (18) | US6465458B1 (enExample) |
| EP (3) | EP2090312A1 (enExample) |
| JP (3) | JP2003503450A (enExample) |
| KR (5) | KR20090087135A (enExample) |
| CN (5) | CN1205935C (enExample) |
| AR (1) | AR035158A1 (enExample) |
| AT (9) | ATE319453T1 (enExample) |
| AU (2) | AU771258B2 (enExample) |
| BR (1) | BR0012136A (enExample) |
| CA (2) | CA2375908C (enExample) |
| CL (3) | CL2008002866A1 (enExample) |
| CO (1) | CO5190662A1 (enExample) |
| CZ (1) | CZ299847B6 (enExample) |
| DE (9) | DE60020613T2 (enExample) |
| DK (4) | DK1459749T3 (enExample) |
| EA (6) | EA006652B1 (enExample) |
| ES (9) | ES2247572T3 (enExample) |
| GE (1) | GEP20094798B (enExample) |
| HU (1) | HUP0201623A3 (enExample) |
| IL (3) | IL147246A0 (enExample) |
| MX (1) | MXPA02000562A (enExample) |
| MY (1) | MY137348A (enExample) |
| NO (4) | NO20016406L (enExample) |
| NZ (2) | NZ533243A (enExample) |
| PE (1) | PE20010684A1 (enExample) |
| PL (1) | PL196996B1 (enExample) |
| PT (5) | PT1632234E (enExample) |
| SK (5) | SK286669B6 (enExample) |
| TW (9) | TWI298255B (enExample) |
| WO (1) | WO2001001973A2 (enExample) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003503450A (ja) * | 1999-07-01 | 2003-01-28 | ファルマシア・アンド・アップジョン・カンパニー | 高選択的ノルエピネフリン再取込みインヒビターおよびその使用方法 |
| YU37602A (sh) * | 1999-12-01 | 2005-07-19 | Ucb S.A. | Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns |
| DE60115872T2 (de) | 2000-04-21 | 2006-07-13 | Pharmacia & Upjohn Co. Llc, Kalamazoo | Cabergolin zur behandlung von fibromyalgie und chronic-fatigue-syndrom |
| BR0110188A (pt) * | 2000-04-21 | 2003-03-05 | Upjohn Co | Compostos selecionados para o tratamento de sìndromes de fibromialgia e de fadiga crÈnica |
| US20040048860A1 (en) * | 2000-10-31 | 2004-03-11 | Jes Olesen | Use of selective noradrenaline reuptake inhibitors for the treatment of tension-type headache |
| CA2426069A1 (en) * | 2000-11-15 | 2002-05-23 | David Michelson | Treatment of anxiety disorders |
| WO2002083141A1 (en) * | 2001-04-17 | 2002-10-24 | Pharmacia & Upjohn Company | Treatment of fibromyalgia and chronic fatigue syndrome |
| US20040048874A1 (en) * | 2001-05-22 | 2004-03-11 | Bardsley Hazel Judith | New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine |
| GB0216027D0 (en) * | 2002-07-10 | 2002-08-21 | Arachnova Therapeutics Ltd | New therapeutic use |
| US20060167074A1 (en) * | 2001-06-19 | 2006-07-27 | Norbert Muller | Methods and compositions for the treatment of psychiatric disorders |
| DE60234873D1 (de) * | 2001-06-19 | 2010-02-04 | Norbert Mueller | Verwendung von COX-2 Inhibitoren zur Behandlung von affectiven Störungen |
| US6602911B2 (en) | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
| AU2002347984A1 (en) * | 2001-11-30 | 2003-06-17 | Eli Lilly And Company | Use of norepinephrine reuptake inhibitors for the treatment of tic disorders |
| DE60223718T2 (de) * | 2001-12-11 | 2008-10-30 | Eli Lilly And Co., Indianapolis | Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen |
| US20040102440A1 (en) * | 2002-07-01 | 2004-05-27 | Wong Erik Ho Fong | Method of promoting smoking cessation |
| JP2005522445A (ja) * | 2002-02-12 | 2005-07-28 | サイプレス バイオサイエンス, インコーポレイテッド | 注意欠陥過活動性障害(ad/hd)の処置方法 |
| CA2483093A1 (en) * | 2002-04-24 | 2003-11-06 | Cypress Bioscience, Inc. | Use of milnacipran or a pharmaceutically acceptable salt thereof for treating chronic low back pain |
| CA2483464C (en) * | 2002-05-17 | 2011-12-20 | Duke University | Method for treating obesity |
| ATE536874T1 (de) * | 2002-05-30 | 2011-12-15 | Neurosearch As | Dreifache monoamin-wiederaufnahmehemmer zur behandlung von chronischen schmerzen |
| AU2003227755B2 (en) * | 2002-06-17 | 2009-01-15 | Pfizer Italia S.R.L. | Pharmaceutical salts of reboxetine |
| AR040680A1 (es) * | 2002-07-25 | 2005-04-13 | Pharmacia Corp | Composicion de tabletas de liberacion sostenida |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| CA2495452A1 (en) * | 2002-08-14 | 2004-02-26 | Pharmacia & Upjohn Company Llc | Use of reboxetine for the treatment of hot flashes |
| GB0219687D0 (en) | 2002-08-23 | 2002-10-02 | Lilly Co Eli | Benzyl morpholine derivatives |
| US7294623B2 (en) | 2002-08-23 | 2007-11-13 | Eli Lilly And Company | Benzyl morpholine derivatives |
| EP1534291B1 (en) | 2002-08-23 | 2008-11-12 | Eli Lilly And Company | 2-(phenylthiomethyl)- morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
| AU2003284005B2 (en) * | 2002-10-03 | 2009-12-17 | Forest Laboratories Holdings Limited | Dosage escalation and divided daily dose of anti-depressants to treat neurological disorders |
| US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US7345096B2 (en) * | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US20040180879A1 (en) * | 2002-10-15 | 2004-09-16 | Deecher Darlene Coleman | Novel method of treating vasomotor symptoms |
| US20040204411A1 (en) * | 2002-12-17 | 2004-10-14 | Pharmacia Corporation | Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof |
| NZ541008A (en) * | 2003-01-13 | 2007-09-28 | Dynogen Pharmaceuticals Inc | Method of treating functional bowel disorders |
| NZ541009A (en) * | 2003-01-13 | 2007-09-28 | Dynogen Pharmaceuticals Inc | Method of treating nausea, vomiting, retching or any combination thereof |
| AU2004227945B2 (en) * | 2003-04-04 | 2006-10-26 | Dynogen Pharmaceuticals, Inc. | Method of treating lower urinary tract disorders |
| ES2639579T3 (es) | 2003-04-29 | 2017-10-27 | Orexigen Therapeutics, Inc. | Composiciones para afectar la pérdida de peso que comprende un antagonista opioide y bupropión |
| WO2004100929A1 (en) | 2003-05-12 | 2004-11-25 | Synergia Pharma, Inc. | Threo-dops controlled release formulation |
| US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
| WO2004105690A2 (en) * | 2003-05-23 | 2004-12-09 | Cypress Bioscience, Inc. | Treatment of chronic pain associated with drug or radiation therapy |
| GB0319793D0 (en) * | 2003-08-22 | 2003-09-24 | Lilly Co Eli | Pyridinylmorpholine derivatives |
| EP1660065A2 (en) * | 2003-08-27 | 2006-05-31 | Eli Lilly And Company | Treatment of pervasive developmental disorders with norepinephrine reuptake inhibitors |
| WO2005025561A1 (en) * | 2003-09-04 | 2005-03-24 | Synergia Pharma, Inc. | Compositions and methods for orthostatic intolerance |
| WO2005025675A1 (en) * | 2003-09-12 | 2005-03-24 | Pfizer Limited | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
| US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
| US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
| US20050130987A1 (en) * | 2003-10-14 | 2005-06-16 | Wyeth | Methods of treating vasomotor symptoms |
| US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
| US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
| US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
| US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
| GB0326148D0 (en) | 2003-11-10 | 2003-12-17 | Lilly Co Eli | Morpholine derivatives |
| KR20060121178A (ko) * | 2003-12-12 | 2006-11-28 | 일라이 릴리 앤드 캄파니 | 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제 |
| WO2005066144A1 (en) * | 2003-12-23 | 2005-07-21 | Eli Lilly And Company | Morpholine derivatives as norepinephrine reuptake inhibitors |
| US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7517899B2 (en) * | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| EA200601798A1 (ru) * | 2004-04-30 | 2007-04-27 | Уорнер-Ламберт Компани Ллс | Замещенные соединения морфолина для лечения расстройств центральной нервной системы |
| KR100871272B1 (ko) * | 2004-04-30 | 2008-11-28 | 화이자 인코포레이티드 | 모폴린 화합물 |
| GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
| EP1763354A2 (en) * | 2004-06-09 | 2007-03-21 | Pfizer Limited | Use of reboxetine for the treatment of pain |
| US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
| US20090227562A1 (en) * | 2004-08-10 | 2009-09-10 | Pfizer Inc. | Combination of a Selective Noradrenaline Reuptake Unhibitor and a PDEV Inhibitor |
| UA86831C2 (uk) | 2004-08-13 | 2009-05-25 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Композиція таблетки пролонгованого вивільнення, яка містить праміпексол або його фармацевтично прийнятну сіль, спосіб її виготовлення та її застосування |
| JP2008514689A (ja) * | 2004-10-01 | 2008-05-08 | ニューロキュア リミテッド | Adhd、cfs、fmおよび鬱病の処置のためのロフェプラミンの薬学的な組成物の使用 |
| US20060293309A1 (en) * | 2005-03-28 | 2006-12-28 | Dynogen Pharmaceuticals, Inc. | Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors |
| US7994220B2 (en) * | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
| JP5180092B2 (ja) | 2005-11-22 | 2013-04-10 | オレキシジェン・セラピューティクス・インコーポレーテッド | インスリン感受性を増すための組成物および方法 |
| US20070253994A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| DK1948155T3 (da) * | 2006-06-28 | 2012-07-02 | Chelsea Therapeutics Inc | Farmaceutiske præparater omfattende droxidopa |
| CN101573103A (zh) | 2006-11-09 | 2009-11-04 | 奥雷西根治疗公司 | 用于施用重量减轻药物的单位剂量包装和方法 |
| ES2480966T3 (es) | 2007-03-09 | 2014-07-29 | Chelsea Therapeutics, Inc. | Droxidopa y composición farmacéutica de la misma para el tratamiento de la fibromialgia |
| WO2008122019A1 (en) * | 2007-04-02 | 2008-10-09 | Cypress Biosciences, Inc. | Improving the tolerability of both mirtazapine and reboxetine by using them in combination |
| EP2152074A4 (en) * | 2007-04-30 | 2011-07-27 | Adolor Corp | (-) - E-10-OH-NT COMPOSITIONS, METHODS OF SYNTHESIS AND USE |
| AU2008248382B2 (en) * | 2007-05-07 | 2013-07-18 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders |
| US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
| US20090233959A1 (en) * | 2008-02-19 | 2009-09-17 | Adolor Corporation | Beloxepin and analogs for the treatment of pain |
| US20090233957A1 (en) * | 2008-02-19 | 2009-09-17 | Adolor Corporation | (-)-beloxepin and methods for its synthesis and use |
| US8475823B2 (en) | 2008-04-18 | 2013-07-02 | Medtronic, Inc. | Baclofen formulation in a polyorthoester carrier |
| US8956642B2 (en) | 2008-04-18 | 2015-02-17 | Medtronic, Inc. | Bupivacaine formulation in a polyorthoester carrier |
| US20110144145A1 (en) | 2008-05-30 | 2011-06-16 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| JP5405571B2 (ja) | 2008-07-24 | 2014-02-05 | セラヴァンス, インコーポレーテッド | 3−(フェノキシフェニルメチル)ピロリジン化合物 |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| WO2010044016A1 (en) * | 2008-10-17 | 2010-04-22 | Pfizer Limited | Novel uses for esreboxetine and racemic reboxetine |
| WO2010120910A1 (en) * | 2009-04-15 | 2010-10-21 | Theravance, Inc. | 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds |
| RU2535669C2 (ru) * | 2009-07-13 | 2014-12-20 | Тереванс, Инк. | 3-феноксиметилпирролидиновые соединения |
| JP5714580B2 (ja) | 2009-07-21 | 2015-05-07 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | 3−フェノキシメチルピロリジン化合物 |
| KR20120124423A (ko) | 2010-01-11 | 2012-11-13 | 오렉시젠 세러퓨틱스 인크. | 주우울증 환자들에 있어서 체중 감량 치료를 제공하는 방법 |
| WO2012051103A1 (en) | 2010-10-11 | 2012-04-19 | Theravance, Inc. | Serotonin reuptake inhibitors |
| WO2012075239A1 (en) | 2010-12-03 | 2012-06-07 | Theravance, Inc. | Serotonin reuptake inhibitors |
| JP5880913B2 (ja) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | パーキンソン病の体幹症状(姿勢反射異常)の治療剤 |
| RS67076B1 (sr) | 2012-06-06 | 2025-08-29 | Nalpropion Pharmaceuticals Llc | Kompozicija za upotrebu u postupku lečenja prekomerne težine i gojaznosti kod pacijenata sa visokim kardiovaskularnim rizikom |
| US10526280B2 (en) | 2014-11-13 | 2020-01-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | (2-amino-4-(arylamino)phenyl carbamates |
| US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
| US11020402B2 (en) | 2018-10-15 | 2021-06-01 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
| US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| WO2021113163A1 (en) * | 2019-12-03 | 2021-06-10 | Axsome Therapeutics, Inc. | Use of reboxetine to treat nervous system disorders |
| EP3693020A1 (en) * | 2019-02-08 | 2020-08-12 | Burmaster International Group GmbH | Potassium enriched topical formulations for pain relief and sleep aid |
| KR20220108122A (ko) * | 2019-12-03 | 2022-08-02 | 액섬 테라퓨틱스, 인크. | 신경계 장애 치료를 위한 레복세틴의 용도 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
| US3742951A (en) | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
| US3996934A (en) | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
| US4031894A (en) | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
| IL56369A (en) | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
| US4465458A (en) * | 1980-03-19 | 1984-08-14 | Matsushita Electric Industrial Co., Ltd. | Apparatus for burning liquid fuel equipped with heating-type fuel vaporizer |
| GB8419683D0 (en) | 1984-08-02 | 1984-09-05 | Erba Farmitalia | 3-substituted derivatives of 1-amino-2-hydroxy-propane |
| GB2167407B (en) | 1984-11-22 | 1988-05-11 | Erba Farmitalia | Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof |
| US4596807A (en) | 1985-03-26 | 1986-06-24 | Serotonin Industries Of Charleston | Method and compositions for controlling pain, depression and sedation |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
| PH30083A (en) | 1991-02-25 | 1996-12-27 | Lilly Co Eli | Treatment of lower urinary tract disorders |
| US5281624A (en) | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
| US5192751A (en) | 1992-07-24 | 1993-03-09 | Eli Lilly And Company | Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence |
| TW344661B (en) | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| IL111786A0 (en) | 1993-12-01 | 1995-01-24 | Max Planck Gesellschaft | Methods of promoting the survival and differentiation of subclasses of cholinergic and serotonergic neurons using fibroblast growth factor-5 |
| CA2134038C (en) * | 1994-06-16 | 1997-06-03 | David Taiwai Wong | Potentiation of drug response |
| ZA958725B (en) | 1994-10-20 | 1997-04-16 | Lilly Co Eli | Treatment of disorders with duloxetine |
| CZ296263B6 (cs) | 1996-03-25 | 2006-02-15 | Eli Lilly And Company | Farmaceutická kompozice pro lécení bolesti a jejípouzití |
| AU2587297A (en) | 1996-03-25 | 1997-10-17 | Eli Lilly And Company | Method for treating pain |
| US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
| US6290986B1 (en) * | 1996-10-24 | 2001-09-18 | Pharmaceutical Applications Associates, Llc | Method and composition for transdermal administration of pharmacologic agents |
| US6572880B2 (en) * | 1996-10-24 | 2003-06-03 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| US6479074B2 (en) * | 1996-10-24 | 2002-11-12 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| WO1999011208A1 (en) | 1997-08-28 | 1999-03-11 | Williams C Donald | Method and composition for transdermal administration of pharmacologic agents |
| US20020015713A1 (en) * | 1996-10-24 | 2002-02-07 | Murdock Robert W. | Methods and transdermal compositions for pain relief |
| ES2125696T3 (es) | 1996-11-27 | 1999-03-01 | Pfleger R Chem Fab | Utilizacion del cloruro de tropsio para la produccion de una preparacion farmaceutica para el tratamiento de disfunciones vesicales. |
| KR20000057548A (ko) | 1996-12-13 | 2000-09-25 | 알프레드 엘. 미첼슨 | 광학적 전송물질 및 결합재 |
| WO1998046227A1 (en) | 1997-04-11 | 1998-10-22 | Eli Lilly And Company | Composition for treating pain |
| US5942530A (en) | 1997-08-28 | 1999-08-24 | Eli Lilly And Company | Method for treating pain |
| US6622036B1 (en) * | 2000-02-09 | 2003-09-16 | Cns Response | Method for classifying and treating physiologic brain imbalances using quantitative EEG |
| UA56257C2 (uk) | 1997-09-23 | 2003-05-15 | Елі Ліллі Енд Компані | Спосіб лікування неадекватної визивної поведінки |
| UA57107C2 (uk) * | 1997-09-23 | 2003-06-16 | Елі Ліллі Енд Компані | Спосіб лікування розладу поведінки |
| AU9214498A (en) | 1997-09-23 | 1999-04-12 | Eli Lilly And Company | Treatment of attention-deficit/hyperactivity disorder |
| AU9692898A (en) | 1997-10-17 | 1999-05-10 | Eli Lilly And Company | Potentiation of pharmaceuticals |
| CN1301164A (zh) * | 1998-04-09 | 2001-06-27 | 法玛西雅厄普约翰美国公司 | 神经病症的新疗法 |
| US6586427B2 (en) * | 1998-04-09 | 2003-07-01 | Pharmacia & Upjohn Company | Treatments for nervous disorders |
| IT1305322B1 (it) | 1998-04-23 | 2001-05-04 | Pharmacia & Upjohn Spa | Uso di reboxetina per il trattamento di disturbi nervosi |
| BR9909559A (pt) | 1998-05-08 | 2000-12-19 | Upjohn Co | Novas combinações de drogas |
| SK20012000A3 (sk) | 1998-06-29 | 2001-08-06 | Pharmaceuticals Applications Asociates, Llc | Transdermálny prostriedok na zmiernenie bolesti |
| US6331571B1 (en) * | 1998-08-24 | 2001-12-18 | Sepracor, Inc. | Methods of treating and preventing attention deficit disorders |
| JP2003503450A (ja) * | 1999-07-01 | 2003-01-28 | ファルマシア・アンド・アップジョン・カンパニー | 高選択的ノルエピネフリン再取込みインヒビターおよびその使用方法 |
| GB2355191A (en) | 1999-10-12 | 2001-04-18 | Laxdale Ltd | Combination formulations for fatigue, head injury and strokes |
| SE9904750D0 (sv) | 1999-12-23 | 1999-12-23 | Pharmacia & Upjohn Ab | New formulation, use and method |
| CN1396829A (zh) | 2000-02-24 | 2003-02-12 | 法玛西雅厄普约翰美国公司 | 新的药物联合形式 |
| US20050096349A1 (en) * | 2003-11-03 | 2005-05-05 | University Of Florida | Methods to prevent or ameliorate medication-, procedure-or stress-induced cognitive and speech dysfunction and methods to optimize cognitive and speech functioning |
-
2000
- 2000-06-22 JP JP2001507467A patent/JP2003503450A/ja active Pending
- 2000-06-22 EP EP09161068A patent/EP2090312A1/en not_active Withdrawn
- 2000-06-22 PT PT05111704T patent/PT1632234E/pt unknown
- 2000-06-22 KR KR1020097015714A patent/KR20090087135A/ko not_active Ceased
- 2000-06-22 AT AT04025513T patent/ATE319453T1/de not_active IP Right Cessation
- 2000-06-22 DK DK04013381T patent/DK1459749T3/da active
- 2000-06-22 AT AT05111704T patent/ATE364386T1/de not_active IP Right Cessation
- 2000-06-22 KR KR1020017016963A patent/KR100704319B1/ko not_active Expired - Fee Related
- 2000-06-22 DE DE60020613T patent/DE60020613T2/de not_active Expired - Lifetime
- 2000-06-22 ES ES04013383T patent/ES2247572T3/es not_active Expired - Lifetime
- 2000-06-22 DE DE60022692T patent/DE60022692T2/de not_active Expired - Lifetime
- 2000-06-22 ES ES05111704T patent/ES2285645T3/es not_active Expired - Lifetime
- 2000-06-22 ES ES00941659T patent/ES2258010T3/es not_active Expired - Lifetime
- 2000-06-22 GE GEAP200011110A patent/GEP20094798B/en unknown
- 2000-06-22 DE DE60023043T patent/DE60023043T2/de not_active Expired - Lifetime
- 2000-06-22 WO PCT/US2000/017256 patent/WO2001001973A2/en not_active Ceased
- 2000-06-22 PT PT00941659T patent/PT1196172E/pt unknown
- 2000-06-22 DK DK00941659T patent/DK1196172T3/da active
- 2000-06-22 SK SK50024-2007A patent/SK286669B6/sk not_active IP Right Cessation
- 2000-06-22 CN CNB008084858A patent/CN1205935C/zh not_active Expired - Fee Related
- 2000-06-22 AT AT04023888T patent/ATE305306T1/de not_active IP Right Cessation
- 2000-06-22 SK SK1938-2001A patent/SK286104B6/sk not_active IP Right Cessation
- 2000-06-22 MX MXPA02000562A patent/MXPA02000562A/es active IP Right Grant
- 2000-06-22 CZ CZ20014625A patent/CZ299847B6/cs not_active IP Right Cessation
- 2000-06-22 EA EA200400589A patent/EA006652B1/ru not_active IP Right Cessation
- 2000-06-22 EA EA200700232A patent/EA011094B1/ru not_active IP Right Cessation
- 2000-06-22 DE DE60019473T patent/DE60019473T2/de not_active Expired - Lifetime
- 2000-06-22 BR BR0012136-3A patent/BR0012136A/pt not_active Application Discontinuation
- 2000-06-22 AT AT04013382T patent/ATE296634T1/de not_active IP Right Cessation
- 2000-06-22 ES ES04013381T patent/ES2246485T3/es not_active Expired - Lifetime
- 2000-06-22 EA EA200501496A patent/EA008381B1/ru not_active IP Right Cessation
- 2000-06-22 EP EP00941659A patent/EP1196172B1/en not_active Expired - Lifetime
- 2000-06-22 DE DE60022917T patent/DE60022917T2/de not_active Expired - Fee Related
- 2000-06-22 KR KR1020057009371A patent/KR100717660B1/ko not_active Expired - Fee Related
- 2000-06-22 SK SK50023-2007A patent/SK286668B6/sk not_active IP Right Cessation
- 2000-06-22 ES ES04013379T patent/ES2239311T3/es not_active Expired - Lifetime
- 2000-06-22 EA EA200200111A patent/EA005029B1/ru not_active IP Right Cessation
- 2000-06-22 AT AT04013383T patent/ATE304358T1/de not_active IP Right Cessation
- 2000-06-22 AT AT00941659T patent/ATE320257T1/de not_active IP Right Cessation
- 2000-06-22 ES ES04025514T patent/ES2246488T3/es not_active Expired - Lifetime
- 2000-06-22 DK DK05111704T patent/DK1632234T3/da active
- 2000-06-22 CA CA002375908A patent/CA2375908C/en not_active Expired - Fee Related
- 2000-06-22 PT PT04013379T patent/PT1459748E/pt unknown
- 2000-06-22 AT AT04013381T patent/ATE305788T1/de not_active IP Right Cessation
- 2000-06-22 CA CA002643231A patent/CA2643231A1/en not_active Abandoned
- 2000-06-22 DE DE60026627T patent/DE60026627T2/de not_active Expired - Fee Related
- 2000-06-22 KR KR1020097015713A patent/KR100948757B1/ko not_active Expired - Fee Related
- 2000-06-22 US US09/599,213 patent/US6465458B1/en not_active Expired - Lifetime
- 2000-06-22 EP EP09161069A patent/EP2087892A3/en not_active Withdrawn
- 2000-06-22 KR KR1020067017835A patent/KR100935277B1/ko not_active Expired - Fee Related
- 2000-06-22 CN CN2004101045241A patent/CN1660110A/zh active Pending
- 2000-06-22 NZ NZ533243A patent/NZ533243A/en unknown
- 2000-06-22 AT AT04025514T patent/ATE305307T1/de not_active IP Right Cessation
- 2000-06-22 PT PT04013382T patent/PT1459750E/pt unknown
- 2000-06-22 ES ES04013382T patent/ES2242175T3/es not_active Expired - Lifetime
- 2000-06-22 NZ NZ515885A patent/NZ515885A/en unknown
- 2000-06-22 SK SK50022-2007A patent/SK286864B6/sk not_active IP Right Cessation
- 2000-06-22 DK DK04013382T patent/DK1459750T3/da active
- 2000-06-22 PL PL352252A patent/PL196996B1/pl not_active IP Right Cessation
- 2000-06-22 ES ES04025513T patent/ES2258251T3/es not_active Expired - Lifetime
- 2000-06-22 SK SK50021-2007A patent/SK286667B6/sk not_active IP Right Cessation
- 2000-06-22 HU HU0201623A patent/HUP0201623A3/hu unknown
- 2000-06-22 AU AU56337/00A patent/AU771258B2/en not_active Ceased
- 2000-06-22 CN CNB2004101045256A patent/CN1289090C/zh not_active Expired - Fee Related
- 2000-06-22 DE DE60026704T patent/DE60026704T2/de not_active Expired - Lifetime
- 2000-06-22 AT AT04013379T patent/ATE292971T1/de not_active IP Right Cessation
- 2000-06-22 DE DE60022916T patent/DE60022916T2/de not_active Expired - Fee Related
- 2000-06-22 DE DE60035232T patent/DE60035232T2/de not_active Expired - Lifetime
- 2000-06-22 EA EA200801806A patent/EA200801806A1/ru unknown
- 2000-06-22 IL IL14724600A patent/IL147246A0/xx not_active IP Right Cessation
- 2000-06-22 PT PT04013383T patent/PT1459751E/pt unknown
- 2000-06-22 EA EA200801805A patent/EA200801805A1/ru unknown
- 2000-06-22 CN CN2004101045237A patent/CN1660109A/zh active Pending
- 2000-06-22 CN CN2004101045222A patent/CN1660108A/zh active Pending
- 2000-06-22 ES ES04023888T patent/ES2246487T3/es not_active Expired - Lifetime
- 2000-06-27 MY MYPI20002899A patent/MY137348A/en unknown
- 2000-06-28 PE PE2000000664A patent/PE20010684A1/es not_active Application Discontinuation
- 2000-06-30 AR ARP000103350A patent/AR035158A1/es unknown
- 2000-07-04 CO CO00049691A patent/CO5190662A1/es not_active Application Discontinuation
- 2000-09-05 TW TW094142128A patent/TWI298255B/zh not_active IP Right Cessation
- 2000-09-05 TW TW089113086A patent/TWI245631B/zh not_active IP Right Cessation
- 2000-09-05 TW TW097124378A patent/TW200922594A/zh unknown
- 2000-09-05 TW TW097124426A patent/TW200914027A/zh unknown
- 2000-09-05 TW TW094142131A patent/TWI294779B/zh active
- 2000-09-05 TW TW092137686A patent/TW200407146A/zh unknown
- 2000-09-05 TW TW094142132A patent/TWI293250B/zh active
- 2000-09-05 TW TW094142126A patent/TWI298254B/zh not_active IP Right Cessation
- 2000-09-05 TW TW097124457A patent/TW200920378A/zh unknown
-
2001
- 2001-12-14 US US10/020,261 patent/US6703389B2/en not_active Expired - Fee Related
- 2001-12-28 NO NO20016406A patent/NO20016406L/no unknown
-
2002
- 2002-01-04 US US10/099,334 patent/US6642235B2/en not_active Expired - Fee Related
- 2002-01-04 US US10/037,344 patent/US6610690B2/en not_active Expired - Lifetime
- 2002-01-23 US US10/055,663 patent/US6987107B2/en not_active Expired - Fee Related
- 2002-09-26 US US10/255,450 patent/US20030040464A1/en not_active Abandoned
-
2003
- 2003-09-24 US US10/669,611 patent/US20040058925A1/en not_active Abandoned
-
2004
- 2004-01-16 US US10/758,864 patent/US7317011B2/en not_active Expired - Fee Related
- 2004-05-18 AU AU2004202096A patent/AU2004202096B2/en not_active Ceased
-
2006
- 2006-02-07 US US11/349,022 patent/US7241762B2/en not_active Expired - Fee Related
- 2006-02-07 US US11/349,373 patent/US7276503B2/en not_active Expired - Fee Related
- 2006-02-07 US US11/348,948 patent/US20060142289A1/en not_active Abandoned
- 2006-02-07 US US11/349,331 patent/US7338953B2/en not_active Expired - Fee Related
- 2006-02-22 JP JP2006045459A patent/JP2006143749A/ja active Pending
- 2006-07-28 US US11/460,775 patent/US20060264436A1/en not_active Abandoned
- 2006-08-02 JP JP2006210418A patent/JP2006321815A/ja active Pending
-
2007
- 2007-10-30 US US11/928,917 patent/US7723334B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/928,812 patent/US20080096890A1/en not_active Abandoned
- 2007-10-30 US US11/928,980 patent/US20080103147A1/en not_active Abandoned
- 2007-10-30 US US11/928,781 patent/US20080103145A1/en not_active Abandoned
- 2007-11-20 IL IL187513A patent/IL187513A0/en unknown
- 2007-11-20 IL IL187512A patent/IL187512A0/en unknown
-
2008
- 2008-09-26 CL CL2008002866A patent/CL2008002866A1/es unknown
- 2008-09-26 CL CL2008002867A patent/CL2008002867A1/es unknown
- 2008-09-26 CL CL2008002868A patent/CL2008002868A1/es unknown
-
2009
- 2009-03-18 NO NO20091168A patent/NO20091168L/no not_active Application Discontinuation
- 2009-03-18 NO NO20091158A patent/NO20091158L/no unknown
- 2009-03-18 NO NO20091159A patent/NO20091159L/no unknown
- 2009-04-27 US US12/430,244 patent/US20090247528A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100948757B1 (ko) | 고선택성 노르에피네프린 재흡수 억제제 및 그의 이용 방법 | |
| EP1632235A2 (en) | Use of highly selective norepinephrine reuptake inhibitors for the treatment of mental disorders | |
| CN1969859A (zh) | 高度选择性去甲肾上腺素再摄取抑制剂及其用途 | |
| HK1103019A (en) | Highly selective norepinephrine reuptake inhibitors and methods of using the same | |
| HK1076726A (en) | Highly selective norepinephrine reuptake inhibitors and methods of using the same | |
| HK1089945A (en) | Highly selective norepinephrine reuptake inhibitors and methods of using the same | |
| HK1076723B (en) | Highly selective norepinephrine reuptake inhibitors and the use for the preparation of the medicament thereof | |
| HK1076725A (en) | Highly selective norepinephrine reuptake inhibitors and methods of using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20090727 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20090826 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20091106 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20100302 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20091106 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |