GB2167407B - Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof - Google Patents
Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereofInfo
- Publication number
- GB2167407B GB2167407B GB08429546A GB8429546A GB2167407B GB 2167407 B GB2167407 B GB 2167407B GB 08429546 A GB08429546 A GB 08429546A GB 8429546 A GB8429546 A GB 8429546A GB 2167407 B GB2167407 B GB 2167407B
- Authority
- GB
- United Kingdom
- Prior art keywords
- enantiomers
- salts
- phenoxy derivatives
- benzyl morpholine
- morpholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08429546A GB2167407B (en) | 1984-11-22 | 1984-11-22 | Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof |
IT22645/85A IT1190420B (en) | 1984-11-22 | 1985-10-29 | BENZYLMORPHOLINE-DERIVED PHENOXY-BASED ENANTIOMERS AND THEIR SALTS |
DE19853540093 DE3540093A1 (en) | 1984-11-22 | 1985-11-12 | ENANTIOMERS OF PHENOXY DERIVATIVES OF BENZYLMORPHOLIN AND SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THEM |
JP60258816A JPH0667916B2 (en) | 1984-11-22 | 1985-11-20 | Enantiomers of phenoxy derivatives of benzylmorpholine and their salts |
FR8517324A FR2573425B1 (en) | 1984-11-22 | 1985-11-22 | ENANTIOMERS OF PHENOXY DERIVATIVES OF BENZYLMORPHOLINE AND THEIR SALTS USEFUL IN PARTICULAR AS ANTIDEPRESSANTS AND THEIR MANUFACTURING METHOD |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08429546A GB2167407B (en) | 1984-11-22 | 1984-11-22 | Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8429546D0 GB8429546D0 (en) | 1985-01-03 |
GB2167407A GB2167407A (en) | 1986-05-29 |
GB2167407B true GB2167407B (en) | 1988-05-11 |
Family
ID=10570118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08429546A Expired GB2167407B (en) | 1984-11-22 | 1984-11-22 | Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPH0667916B2 (en) |
DE (1) | DE3540093A1 (en) |
FR (1) | FR2573425B1 (en) |
GB (1) | GB2167407B (en) |
IT (1) | IT1190420B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1305322B1 (en) | 1998-04-23 | 2001-05-04 | Pharmacia & Upjohn Spa | Use of reboxetine for treating obsessive compulsive disorder and panic disorder |
DK1459750T3 (en) | 1999-07-01 | 2005-08-15 | Pharmacia & Upjohn Co Llc | (S, S) rebexetine for the treatment of fibromyalgia and other somatoform disorders |
EP1629843A3 (en) * | 1999-07-01 | 2006-03-15 | Pharmacia & Upjohn Company LLC | Reboxetine for treating chronic fatigue syndrome |
CO5210862A1 (en) * | 1999-09-15 | 2002-10-30 | Alza Corp | DOSAGE FORMS AND METHODS TO PROVIDE REBOXETINE EFFECTIVE THERAPY WITH DOSAGE ONCE A DAY |
CN1662511B (en) * | 2002-06-17 | 2010-06-09 | 辉瑞意大利公司 | Pharmaceutical salts of reboxetine |
AU2003269923A1 (en) | 2002-08-23 | 2004-03-11 | Eli Lilly And Company | 2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
AU2003261245A1 (en) | 2002-08-23 | 2004-03-11 | Eli Lilly And Company | Benzyl morpholine derivatives |
GB0219687D0 (en) | 2002-08-23 | 2002-10-02 | Lilly Co Eli | Benzyl morpholine derivatives |
GB0319793D0 (en) * | 2003-08-22 | 2003-09-24 | Lilly Co Eli | Pyridinylmorpholine derivatives |
WO2005053663A2 (en) * | 2003-11-24 | 2005-06-16 | Eli Lilly And Company | Norepinephrine reuptake inhibitors useful for treatment of cognitive failure |
PL1691811T3 (en) | 2003-12-11 | 2014-12-31 | Sunovion Pharmaceuticals Inc | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
WO2005082869A1 (en) * | 2004-02-20 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Method for the preparation of aryl ethers |
RU2330012C2 (en) * | 2004-02-20 | 2008-07-27 | Фармация Энд Апджон Компани Ллс | Method of obtaining aryl ethers |
GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
JP4185154B2 (en) | 2004-04-30 | 2008-11-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | Substituted morpholine compounds for the treatment of central nervous system disorders |
PT2076508E (en) | 2006-10-18 | 2011-03-07 | Pfizer Prod Inc | Biaryl ether urea compounds |
US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
-
1984
- 1984-11-22 GB GB08429546A patent/GB2167407B/en not_active Expired
-
1985
- 1985-10-29 IT IT22645/85A patent/IT1190420B/en active
- 1985-11-12 DE DE19853540093 patent/DE3540093A1/en not_active Withdrawn
- 1985-11-20 JP JP60258816A patent/JPH0667916B2/en not_active Expired - Lifetime
- 1985-11-22 FR FR8517324A patent/FR2573425B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2573425B1 (en) | 1988-12-23 |
GB8429546D0 (en) | 1985-01-03 |
GB2167407A (en) | 1986-05-29 |
IT1190420B (en) | 1988-02-16 |
DE3540093A1 (en) | 1986-05-28 |
JPS61129174A (en) | 1986-06-17 |
FR2573425A1 (en) | 1986-05-23 |
JPH0667916B2 (en) | 1994-08-31 |
IT8522645A0 (en) | 1985-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE20 | Patent expired after termination of 20 years |
Effective date: 20041121 |