GB2167407B - Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof - Google Patents

Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof

Info

Publication number
GB2167407B
GB2167407B GB08429546A GB8429546A GB2167407B GB 2167407 B GB2167407 B GB 2167407B GB 08429546 A GB08429546 A GB 08429546A GB 8429546 A GB8429546 A GB 8429546A GB 2167407 B GB2167407 B GB 2167407B
Authority
GB
United Kingdom
Prior art keywords
enantiomers
salts
phenoxy derivatives
benzyl morpholine
morpholine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08429546A
Other versions
GB2167407A (en
GB8429546D0 (en
Inventor
Piero Melloni
Arturo Della Torre
Giovanni Carniel
Alessandro Rossi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Priority to GB08429546A priority Critical patent/GB2167407B/en
Publication of GB8429546D0 publication Critical patent/GB8429546D0/en
Priority to IT22645/85A priority patent/IT1190420B/en
Priority to DE19853540093 priority patent/DE3540093A1/en
Priority to JP60258816A priority patent/JPH0667916B2/en
Priority to FR8517324A priority patent/FR2573425B1/en
Publication of GB2167407A publication Critical patent/GB2167407A/en
Application granted granted Critical
Publication of GB2167407B publication Critical patent/GB2167407B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
GB08429546A 1984-11-22 1984-11-22 Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof Expired GB2167407B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB08429546A GB2167407B (en) 1984-11-22 1984-11-22 Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof
IT22645/85A IT1190420B (en) 1984-11-22 1985-10-29 BENZYLMORPHOLINE-DERIVED PHENOXY-BASED ENANTIOMERS AND THEIR SALTS
DE19853540093 DE3540093A1 (en) 1984-11-22 1985-11-12 ENANTIOMERS OF PHENOXY DERIVATIVES OF BENZYLMORPHOLIN AND SALTS THEREOF, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THEM
JP60258816A JPH0667916B2 (en) 1984-11-22 1985-11-20 Enantiomers of phenoxy derivatives of benzylmorpholine and their salts
FR8517324A FR2573425B1 (en) 1984-11-22 1985-11-22 ENANTIOMERS OF PHENOXY DERIVATIVES OF BENZYLMORPHOLINE AND THEIR SALTS USEFUL IN PARTICULAR AS ANTIDEPRESSANTS AND THEIR MANUFACTURING METHOD

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08429546A GB2167407B (en) 1984-11-22 1984-11-22 Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof

Publications (3)

Publication Number Publication Date
GB8429546D0 GB8429546D0 (en) 1985-01-03
GB2167407A GB2167407A (en) 1986-05-29
GB2167407B true GB2167407B (en) 1988-05-11

Family

ID=10570118

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08429546A Expired GB2167407B (en) 1984-11-22 1984-11-22 Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof

Country Status (5)

Country Link
JP (1) JPH0667916B2 (en)
DE (1) DE3540093A1 (en)
FR (1) FR2573425B1 (en)
GB (1) GB2167407B (en)
IT (1) IT1190420B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1305322B1 (en) 1998-04-23 2001-05-04 Pharmacia & Upjohn Spa Use of reboxetine for treating obsessive compulsive disorder and panic disorder
DK1632234T3 (en) 1999-07-01 2007-09-17 Pharmacia & Upjohn Co Llc (S, S) reboxetine for the treatment of chronic fatigue syndrome
DK1500396T3 (en) * 1999-07-01 2005-12-19 Pharmacia & Upjohn Co Llc Reboxetine for the treatment of migraine headaches
CO5210862A1 (en) 1999-09-15 2002-10-30 Alza Corp DOSAGE FORMS AND METHODS TO PROVIDE REBOXETINE EFFECTIVE THERAPY WITH DOSAGE ONCE A DAY
JP4563172B2 (en) * 2002-06-17 2010-10-13 ファイザー イタリア ソシエタ ア レスポンサビリタ リミタータ Reboxetine pharmaceutical salt
DE60324685D1 (en) * 2002-08-23 2008-12-24 Lilly Co Eli 2- (PHENYLTHIOMETHYL) - MORPHOLIN DERIVATIVES FOR USE AS SELECTIVE NOREPINEPHRINE RECOVERY INHIBITORS
ES2264028T3 (en) 2002-08-23 2006-12-16 Eli Lilly And Company BENCILMORPHOLINE DERIVATIVES.
GB0219687D0 (en) 2002-08-23 2002-10-02 Lilly Co Eli Benzyl morpholine derivatives
GB0319793D0 (en) 2003-08-22 2003-09-24 Lilly Co Eli Pyridinylmorpholine derivatives
WO2005053663A2 (en) * 2003-11-24 2005-06-16 Eli Lilly And Company Norepinephrine reuptake inhibitors useful for treatment of cognitive failure
EP2343073A3 (en) 2003-12-11 2011-10-12 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
EP1730094A1 (en) * 2004-02-20 2006-12-13 Pharmacia & Upjohn Company LLC Method for the preparation of aryl ethers
WO2005082869A1 (en) * 2004-02-20 2005-09-09 Pharmacia & Upjohn Company Llc Method for the preparation of aryl ethers
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
KR100943555B1 (en) * 2004-04-30 2010-02-22 워너-램버트 캄파니 엘엘씨 Substituted morpholine compounds for the treatment of central nervous system disorders
WO2008047229A2 (en) 2006-10-18 2008-04-24 Pfizer Products Inc. Biaryl ether urea compounds
US20100069389A1 (en) * 2008-09-06 2010-03-18 Bionevia Pharmaceuticals, Inc. Novel forms of reboxetine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL56369A (en) * 1978-01-20 1984-05-31 Erba Farmitalia Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
JPH0667916B2 (en) 1994-08-31
GB2167407A (en) 1986-05-29
IT8522645A0 (en) 1985-10-29
DE3540093A1 (en) 1986-05-28
FR2573425A1 (en) 1986-05-23
FR2573425B1 (en) 1988-12-23
GB8429546D0 (en) 1985-01-03
IT1190420B (en) 1988-02-16
JPS61129174A (en) 1986-06-17

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20041121