CY1106665T1 - Συσκευη εγχυτη φαρμακου με συστημα οδηγησης που διευκολυνει την επαναφορα - Google Patents

Συσκευη εγχυτη φαρμακου με συστημα οδηγησης που διευκολυνει την επαναφορα

Info

Publication number
CY1106665T1
CY1106665T1 CY20071100575T CY071100575T CY1106665T1 CY 1106665 T1 CY1106665 T1 CY 1106665T1 CY 20071100575 T CY20071100575 T CY 20071100575T CY 071100575 T CY071100575 T CY 071100575T CY 1106665 T1 CY1106665 T1 CY 1106665T1
Authority
CY
Cyprus
Prior art keywords
pen
injection
nut
drive
cartridge
Prior art date
Application number
CY20071100575T
Other languages
English (en)
Inventor
William Godwin Atterbury
Mark Gerard Diller
Peter Andrew Gaydos
Shannon Marie-Lynn Hoste
Steven Michael Madland
Donna Marie Taylor
Bobby Lee Walters
Douglas Edward Boyd
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1106665T1 publication Critical patent/CY1106665T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/12Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable using electric or magnetic means
    • G01D5/244Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable using electric or magnetic means influencing characteristics of pulses or pulse trains; generating pulses or pulse trains
    • G01D5/249Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable using electric or magnetic means influencing characteristics of pulses or pulse trains; generating pulses or pulse trains using pulse code
    • G01D5/2497Absolute encoders
    • GPHYSICS
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    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/12Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable using electric or magnetic means
    • G01D5/25Selecting one or more conductors or channels from a plurality of conductors or channels, e.g. by closing contacts
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    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
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    • A61M2005/3125Details specific display means, e.g. to indicate dose setting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
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    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
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    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/585Means for facilitating use, e.g. by people with impaired vision by visual feedback having magnification means, e.g. magnifying glasses
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    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
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    • A61M2205/6027Electric-conductive bridges closing detection circuits, with or without identifying elements, e.g. resistances, zener-diodes
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    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Basic Packing Technique (AREA)

Abstract

Μία ιατρική συσκευή εγχυτή όπως μία πένα έγχυσης. Η πένα έγχυσης περιλαμβάνει ένα επιδεκτικό επαναφοράς, σύστημα οδήγησης εμβόλου φυσιγγίου που περιλαμβάνει ένα αξονικά κινητό περικόχλιο, έναν κοχλία συμπλοκής εμβόλου φυσιγγίου, και ένα συμπλέκτη κίνησης μετακινήσιμο με το περικόχλιο και ο οποίος όταν περιστρέφεται προκαλεί την κοχλίωση του κοχλία διαμέσου του περικοχλίου. Όταν ένα σύστημα φυσιγγίου είναι τοποθετημένο στη βάση πένας, το κινητό περικόχλιο και ο συμπλέκτης οδήγησης μετατοπίζονται κεντρικά έτσι ώστε ο συμπλέκτης οδήγησης να βρίσκεται σε συμπλοκή μετάδοσης ροπής με ένα επιδεκτικό περιστροφής μέλος κίνησης της πένας, έτσι ώστε η περιστροφή αυτού του μέλους οδήγησης να επιφέρει την προώθηση του κοχλία οδήγησης διαμέσου του περικοχλίου στην περιφερική κατεύθυνση. Όταν το σύστημα φυσιγγίου δεν είναι τοποθετημένο στη βάση πένας, το κινητό περικόχλιο και ο συμπλέκτης οδήγησης είναι πολωμένοι περιφερικά για αποσυμπλοκή του συμπλέκτη οδήγησης από συμπλοκή μετάδοσης ροπής με το επιδεκτικό περιστροφής μέλος οδήγησης και για να επιτρέπεται μέσω αυτού η επαναφορά του κοχλία οδήγησης κεντρικά διαμέσου του περικοχλίου σε μία θέση περισσότερο συμπτυγμένη μέσα στη βάση πένας. Η πένα έγχυσης μπορεί να περιλαμβάνει επίσης ένα σύστημα μηχανισμού ηχητικής ένδειξης έγχυσης που έχει ένα κολάρο διατεταγμένο ομοαξονικά επάνω σε ένα χιτώνιο οδήγησης και το οποίο ταλαντώνεται αξονικά επάνω στο χιτώνιο οδήγησης που περιστρέφεται κατά τη χορήγηση φαρμάκου για παροχή ενός ακουστικού ήχου ένδειξης που υποδεικνύει τη χρήση έγχυσης της πένας. Η πένα έγχυσης μπορεί να περιλαμβάνει επίσης έναν επιδεκτικό δοσολογίας ποσοτικό αναγνωριστή που χρησιμοποιεί μία περιστροφική μήτρα και έναν αισθητήρα για ηλεκτρική ανίχνευση της διάταξης του μηχανισμού καθορισμού δόσης της πένας, ο οποίος αναγνωριστής μπορεί να είναι μέρος ενός συστήματος ένδειξης θεραπευτικής δόσης που χρησιμοποιεί έναν αναγνωστήρα φυσιγγίου για αναγνώριση μίας συγκέντρωσης φαρμάκου έτσι ώστε να επιτρέπεται ένας αυτόματος προσδιορισμός μίας θεραπευτικής δόσης. Η πένα έγχυσης μπορεί να περιλαμβάνει επιπλέον ένα σύστημα για επιλεκτική περιστροφή ενός χιτωνίου οδήγησης της πένας, το οποίο σύστημα έχει έναν επιλογέα που περιστρέφεται κατά τον καθορισμό δόσης και ο οποίος μετακινείται χωρίς περιστροφή κατά την έγχυση δόσης.
CY20071100575T 2001-05-16 2007-04-26 Συσκευη εγχυτη φαρμακου με συστημα οδηγησης που διευκολυνει την επαναφορα CY1106665T1 (el)

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US32419901P 2001-09-21 2001-09-21
PCT/US2002/011876 WO2002092153A2 (en) 2001-05-16 2002-05-08 Medication injector apparatus with drive assembly that facilitates reset

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