USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
CA2965865C
(en)
|
2002-07-18 |
2021-10-19 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
JP5144499B2
(ja)
|
2006-03-31 |
2013-02-13 |
中外製薬株式会社 |
二重特異性抗体を精製するための抗体改変方法
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
PE20120591A1
(es)
*
|
2009-04-02 |
2012-05-23 |
Roche Glycart Ag |
Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla
|
PL2417156T3
(pl)
|
2009-04-07 |
2015-07-31 |
Roche Glycart Ag |
Trójwartościowe, bispecyficzne przeciwciała
|
MX2011010169A
(es)
|
2009-04-07 |
2011-10-11 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-1/anti-c-met.
|
BRPI1012589A2
(pt)
|
2009-04-07 |
2016-03-22 |
Roche Glycart Ag |
anticorpos bi-específicos anti-erbb-3/anti-c-met
|
JP5719354B2
(ja)
*
|
2009-05-27 |
2015-05-20 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
三重又は四重特異性抗体
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US8703132B2
(en)
*
|
2009-06-18 |
2014-04-22 |
Hoffmann-La Roche, Inc. |
Bispecific, tetravalent antigen binding proteins
|
WO2011034605A2
(en)
|
2009-09-16 |
2011-03-24 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
DK2519543T3
(en)
*
|
2009-12-29 |
2016-09-26 |
Emergent Product Dev Seattle |
HETERODIMER BINDING PROTEINS AND USE THEREOF
|
JP5104996B2
(ja)
|
2010-01-29 |
2012-12-19 |
東レ株式会社 |
ポリ乳酸系樹脂シート
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
TWI426920B
(zh)
*
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
雙專一性、雙價抗-vegf/抗-ang-2抗體
|
EP3434694B1
(en)
|
2010-04-09 |
2020-12-30 |
Critical Care Diagnostics, Inc. |
Soluble human st-2 antibodies and assays
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
TW201204388A
(en)
|
2010-06-18 |
2012-02-01 |
Genentech Inc |
Anti-Axl antibodies and methods of use
|
EP2824457A1
(en)
|
2010-07-19 |
2015-01-14 |
F. Hoffmann-La Roche AG |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
RU2013104039A
(ru)
|
2010-07-19 |
2014-08-27 |
Ф. Хоффманн-Ля Рош Аг |
Способ идентификации пациента с повышенной вероятностью ответа на противораковую терапию
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
JP2013541937A
(ja)
|
2010-08-05 |
2013-11-21 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗mhc抗体−抗ウイルス性サイトカイン融合タンパク質
|
DK2606064T3
(en)
|
2010-08-16 |
2015-04-20 |
Novimmune Sa |
Methods for generating multispecific and multivalent antibodies
|
BR112013001847A2
(pt)
|
2010-08-24 |
2016-05-31 |
Hoffmann La Roche |
anticorpo biespecífico, método de preparação do anticorpo biespecífico, do anticorpo biespecífico trivalente, métodos e composição farmacêutica
|
CN103429620B
(zh)
|
2010-11-05 |
2018-03-06 |
酵活有限公司 |
在Fc结构域中具有突变的稳定异源二聚的抗体设计
|
WO2012073985A1
(ja)
|
2010-11-30 |
2012-06-07 |
中外製薬株式会社 |
細胞傷害誘導治療剤
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
BR112013019975A2
(pt)
*
|
2011-02-28 |
2017-08-01 |
Hoffmann La Roche |
proteínas de ligação de antígeno, composição farmacêutica, uso de uma proteína de ligação de antígeno, método para o tratamento de um paciente e método para a preparação de uma proteína de ligação de antígeno, ácido nucleico, vetor e célula hospedeira"
|
CN103403025B
(zh)
|
2011-02-28 |
2016-10-12 |
弗·哈夫曼-拉罗切有限公司 |
单价抗原结合蛋白
|
IN2013MN01438A
(es)
*
|
2011-03-17 |
2015-06-12 |
Univ Ramot |
|
KR20140031217A
(ko)
|
2011-04-20 |
2014-03-12 |
로슈 글리카트 아게 |
혈액-뇌 차단벽의 pH 의존적 통과를 위한 방법 및 구축물
|
AR086924A1
(es)
|
2011-06-15 |
2014-01-29 |
Hoffmann La Roche |
Anticuerpos anti-receptor de epo humano y los metodos para su utilizacion
|
JP6246711B2
(ja)
|
2011-06-22 |
2017-12-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
複合体を含むmhcクラスiを用いてウイルス特異的細胞傷害性t細胞を循環させることによる標的細胞の除去
|
US20130078250A1
(en)
*
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
KR101681818B1
(ko)
|
2011-08-23 |
2016-12-01 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
KR101886983B1
(ko)
*
|
2011-08-23 |
2018-08-08 |
로슈 글리카트 아게 |
2 개의 fab 단편을 포함하는 fc-부재 항체 및 이용 방법
|
RU2650775C2
(ru)
*
|
2011-08-23 |
2018-04-17 |
Рош Гликарт Аг |
Биспецифические антигенсвязывающие молекулы
|
WO2013026833A1
(en)
*
|
2011-08-23 |
2013-02-28 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
MX2014002996A
(es)
*
|
2011-09-23 |
2014-05-28 |
Roche Glycart Ag |
Anticuerpos anti - egfr/anti - igf-1r bisespecificos.
|
EP2787078B1
(en)
|
2011-10-31 |
2019-05-22 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain
|
JP6326371B2
(ja)
|
2011-11-04 |
2018-05-16 |
ザイムワークス,インコーポレイテッド |
Fcドメインにおける変異を有する安定なヘテロ二量体抗体デザイン
|
JP6203747B2
(ja)
|
2011-12-19 |
2017-09-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多特異性結合体の遊離結合パートナーの検出方法
|
PL2794878T3
(pl)
|
2011-12-22 |
2020-07-27 |
F.Hoffmann-La Roche Ag |
Organizacja wektora ekspresyjnego, nowe sposoby generowania komórek produkcyjnych i ich zastosowanie do rekombinowanej produkcji polipeptydów
|
CA2854246A1
(en)
|
2011-12-22 |
2013-06-27 |
F. Hoffmann-La Roche Ag |
Full length antibody display system for eukaryotic cells and its use
|
CA3149402A1
(en)
|
2011-12-22 |
2013-06-27 |
F. Hoffman-La Roche Ag |
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
|
CN106443016B
(zh)
|
2012-02-01 |
2019-08-13 |
弗·哈夫曼-拉罗切有限公司 |
用于检测多特异性结合物的结合搭档的方法
|
US10633451B2
(en)
|
2012-02-03 |
2020-04-28 |
Hoffmann-La Roche Inc. |
Bispecific antibody molecules with antigen-transfected T-cells and their use in medicine
|
WO2013119966A2
(en)
|
2012-02-10 |
2013-08-15 |
Genentech, Inc. |
Single-chain antibodies and other heteromultimers
|
CA2860600C
(en)
|
2012-02-15 |
2022-07-26 |
F. Hoffmann-La Roche Ag |
Fc-receptor based affinity chromatography
|
WO2013134414A1
(en)
*
|
2012-03-06 |
2013-09-12 |
Galaxy Biotech, Llc |
Bispecific antibodies with an fgf2 binding domain
|
KR101674784B1
(ko)
|
2012-04-05 |
2016-11-09 |
에프. 호프만-라 로슈 아게 |
인간 tweak 및 인간 il17에 대한 이중특이적 항체 및 이의 용도
|
MX360110B
(es)
|
2012-04-20 |
2018-10-23 |
Merus Nv |
Metodos y medios para la produccion de moleculas de tipo ig.
|
US9062120B2
(en)
|
2012-05-02 |
2015-06-23 |
Janssen Biotech, Inc. |
Binding proteins having tethered light chains
|
WO2013174873A1
(en)
|
2012-05-24 |
2013-11-28 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
BR112014032193A2
(pt)
|
2012-06-27 |
2017-06-27 |
Hoffmann La Roche |
métodos de produção de anticorpos biespecíficos e de determinação de combinação, anticorpo biespecífico, formulação e uso de anticorpo biespecífico
|
CN104411718B
(zh)
|
2012-06-27 |
2018-04-24 |
弗·哈夫曼-拉罗切有限公司 |
用于制备包含特异性结合靶的至少一种结合实体的抗体Fc区缀合物的方法及其用途
|
CN104411725B
(zh)
|
2012-07-04 |
2018-09-28 |
弗·哈夫曼-拉罗切有限公司 |
抗生物素抗体及使用方法
|
EP3138578B1
(en)
|
2012-07-04 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Anti-theophylline antibodies and methods of use
|
BR112014029403A2
(pt)
|
2012-07-04 |
2018-10-09 |
F. Hoffmann-La Roche Ag |
conjugados, anticorpo e formulação farmacêutica
|
EP3495387B1
(en)
|
2012-07-13 |
2021-09-01 |
Roche Glycart AG |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
BR112015000665A2
(pt)
|
2012-07-13 |
2017-06-27 |
Hoffmann La Roche |
método para a determinação da quantidade de um anticorpo
|
MX2015002407A
(es)
|
2012-09-14 |
2015-06-22 |
Hoffmann La Roche |
Metodo para produccion y seleccion de moleculas que comprenden al menos dos entidades diferentes y usos del mismo.
|
CN110066338B
(zh)
|
2012-09-27 |
2024-04-09 |
美勒斯公司 |
作为T细胞衔接器的双特异性IgG抗体
|
EP2904093B1
(en)
|
2012-10-03 |
2019-04-10 |
Zymeworks Inc. |
Methods of quantitating heavy and light chain polypeptide pairs
|
JP6273205B2
(ja)
|
2012-10-05 |
2018-01-31 |
協和発酵キリン株式会社 |
ヘテロダイマータンパク質組成物
|
CA2879768A1
(en)
*
|
2012-10-08 |
2014-04-17 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
CN110669136A
(zh)
*
|
2012-11-05 |
2020-01-10 |
全药工业株式会社 |
抗体或抗体组合物的制备方法
|
CA2884431A1
(en)
|
2012-11-08 |
2014-05-15 |
F. Hoffmann-La Roche Ag |
Her3 antigen binding proteins binding to the beta-hairpin of her3
|
EP3878964A1
(en)
|
2012-11-27 |
2021-09-15 |
Ajou University Industry-Academic Cooperation Foundation |
Ch3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
|
US9914785B2
(en)
*
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
MX2015006758A
(es)
|
2012-11-28 |
2016-06-10 |
Zymeworks Inc |
Pares de cadena pesada-cadena ligera de inmunoglobulina modificados geneticamente y usos de estos.
|
EP2948475A2
(en)
*
|
2013-01-23 |
2015-12-02 |
AbbVie Inc. |
Methods and compositions for modulating an immune response
|
CN110845618A
(zh)
|
2013-02-26 |
2020-02-28 |
罗切格利卡特公司 |
双特异性t细胞活化抗原结合分子
|
EP2961770A1
(en)
*
|
2013-02-26 |
2016-01-06 |
Roche Glycart AG |
Bispecific t cell activating antigen binding molecules
|
EA201891502A1
(ru)
|
2013-02-26 |
2018-12-28 |
Роше Гликарт Аг |
Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
CA2904806C
(en)
|
2013-04-29 |
2021-11-23 |
F. Hoffmann-La Roche Ag |
Human fcrn-binding modified antibodies and methods of use
|
SG10201810481UA
(en)
|
2013-04-29 |
2018-12-28 |
Hoffmann La Roche |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
PL2992010T3
(pl)
|
2013-04-29 |
2021-08-23 |
F.Hoffmann-La Roche Ag |
Modyfikowane asymetryczne przeciwciała wiążące receptor Fc i sposoby ich stosowania
|
EP3027649B1
(en)
|
2013-08-01 |
2020-04-01 |
F.Hoffmann-La Roche Ag |
Tnfa-il-17 bispecific antibodies
|
WO2015025054A1
(en)
|
2013-08-22 |
2015-02-26 |
Medizinische Universität Wien |
Dye-specific antibodies for prestained molecular weight markers and methods producing the same
|
PT3050896T
(pt)
|
2013-09-27 |
2021-08-24 |
Chugai Pharmaceutical Co Ltd |
Processo para a produção de heteromultímeros de polipéptidos
|
BR112016006929A2
(pt)
*
|
2013-10-11 |
2017-09-19 |
Hoffmann La Roche |
Anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, métodos de preparação de anticorpo, de tratamento de pacientes e de geração de um anticorpo, composição farmacêutica e uso do anticorpo
|
KR102399292B1
(ko)
|
2013-11-21 |
2022-05-17 |
에프. 호프만-라 로슈 아게 |
항-알파-시누클레인 항체 및 사용 방법
|
CA2931356A1
(en)
|
2013-11-27 |
2015-06-04 |
Zymeworks Inc. |
Bispecific antigen-binding constructs targeting her2
|
WO2015091738A1
(en)
|
2013-12-20 |
2015-06-25 |
F. Hoffmann-La Roche Ag |
Bispecific her2 antibodies and methods of use
|
DK3083680T3
(da)
|
2013-12-20 |
2020-03-16 |
Hoffmann La Roche |
Humaniserede anti-Tau(pS422)-antistoffer og fremgangsmåder til anvendelse
|
RU2769133C2
(ru)
*
|
2013-12-30 |
2022-03-28 |
Эпимаб Биотерапьютикс Инк. |
Иммуноглобулин с тандемным расположением fab-фрагментов и его применение
|
WO2015101587A1
(en)
|
2014-01-03 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Covalently linked helicar-anti-helicar antibody conjugates and uses thereof
|
RU2682754C2
(ru)
|
2014-01-03 |
2019-03-21 |
Ф. Хоффманн-Ля Рош Аг |
Конъюгаты полипептидного токсина и антитела, соединенных ковалентной связью
|
JP6476194B2
(ja)
|
2014-01-03 |
2019-02-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
二重特異性抗ハプテン/抗血液脳関門受容体抗体、それらの複合体、及び血液脳関門シャトルとしてのそれらの使用
|
EP3092251B1
(en)
|
2014-01-06 |
2021-01-20 |
F. Hoffmann-La Roche AG |
Monovalent blood brain barrier shuttle modules
|
MX2016008782A
(es)
|
2014-01-15 |
2016-09-08 |
Hoffmann La Roche |
Variantes de region fc con union mejorada de la proteina a.
|
JP6786392B2
(ja)
|
2014-01-15 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
FcRn結合特性が改変され、プロテインA結合特性が保持されているFc領域変異体
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
WO2015130172A1
(en)
|
2014-02-28 |
2015-09-03 |
Merus B.V. |
Antibodies that bind egfr and erbb3
|
US11279770B2
(en)
|
2014-02-28 |
2022-03-22 |
Merus N.V. |
Antibody that binds ErbB-2 and ErbB-3
|
HUE048531T2
(hu)
|
2014-03-14 |
2020-07-28 |
Novartis Ag |
Antitest molekulák a LAG-3-hoz és ezek felhasználása
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
JP6666262B2
(ja)
|
2014-04-02 |
2020-03-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性抗体の軽鎖誤対合を検出するための方法
|
UA117289C2
(uk)
*
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
US11485790B2
(en)
|
2014-04-07 |
2022-11-01 |
Chugai Seiyaku Kabushiki Kaisha |
Immunoactivating antigen-binding molecule
|
US11505605B2
(en)
|
2014-05-13 |
2022-11-22 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
EP2944962A1
(en)
*
|
2014-05-14 |
2015-11-18 |
UCB Biopharma SPRL |
Method for determining antibody specificity
|
AU2015265457B2
(en)
|
2014-05-28 |
2021-02-18 |
Zymeworks Bc Inc. |
Modified antigen binding polypeptide constructs and uses thereof
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
MX2016015280A
(es)
|
2014-06-26 |
2017-03-03 |
Hoffmann La Roche |
Anticuerpos anti-bromodesoxiuridina(brdu) y metodos de uso.
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
EP3166966A1
(en)
|
2014-07-10 |
2017-05-17 |
Affiris AG |
Substances and methods for the use in prevention and/or treatment in huntington's disease
|
RU2751660C2
(ru)
|
2014-07-21 |
2021-07-15 |
Новартис Аг |
Лечение злокачественного новообразования с использованием гуманизированного химерного антигенного рецептора против всма
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
KR102594343B1
(ko)
|
2014-07-21 |
2023-10-26 |
노파르티스 아게 |
Cd33 키메라 항원 수용체를 사용한 암의 치료
|
EP3174546B1
(en)
|
2014-07-31 |
2019-10-30 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
DK3177643T3
(da)
|
2014-08-04 |
2019-07-15 |
Hoffmann La Roche |
Bispecifikke T-celle-aktiverende antigenbindende molekyler
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
EP3183268B1
(en)
|
2014-08-19 |
2020-02-12 |
Novartis AG |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
PL3194443T3
(pl)
|
2014-09-17 |
2022-01-31 |
Novartis Ag |
Nakierowywanie komórek cytotoksycznych za pośrednictwem receptorów chimerycznych do immunoterapii adoptywnej
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
ES2850325T3
(es)
|
2014-10-09 |
2021-08-27 |
Engmab Sarl |
Anticuerpos biespecíficos contra CD3epsilon y ROR1
|
TN2017000129A1
(en)
|
2014-10-14 |
2018-10-19 |
Dana Farber Cancer Inst Inc |
Antibody molecules to pd-l1 and uses thereof
|
AR102521A1
(es)
|
2014-11-06 |
2017-03-08 |
Hoffmann La Roche |
Variantes de región fc con unión de fcrn modificada y métodos de utilización
|
BR112017006591A2
(pt)
|
2014-11-06 |
2018-01-16 |
Hoffmann La Roche |
polipeptídeo heterodimérico, formulação farmacêutica e uso de um polipeptídeo heterodimérico
|
HUE054122T2
(hu)
|
2014-11-14 |
2021-08-30 |
Hoffmann La Roche |
TNF-családba tartozó ligandum-trimert tartalmazó antigénkötõ molekulák
|
ES2835823T3
(es)
|
2014-11-20 |
2021-06-23 |
Hoffmann La Roche |
Politerapia de moléculas de unión a antígeno biespecíficas activadoras de linfocitos T para CD3 y para el receptor de folato 1 (FolR1) y antagonistas de la unión al eje de PD-1
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
WO2016087514A1
(en)
|
2014-12-02 |
2016-06-09 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
CN107001482B
(zh)
|
2014-12-03 |
2021-06-15 |
豪夫迈·罗氏有限公司 |
多特异性抗体
|
WO2016096788A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Assay and method for determining cdc eliciting antibodies
|
LT3280729T
(lt)
|
2015-04-08 |
2022-08-10 |
Novartis Ag |
Terapijos cd20, terapijos cd22 ir kombinuotos terapijos su cd19 chimerinį antigeno receptorių (car) ekspresuojančia ląstele
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
CA2980189A1
(en)
|
2015-04-24 |
2016-10-27 |
Genentech, Inc. |
Multispecific antigen-binding proteins
|
EP3310811B1
(en)
|
2015-06-16 |
2021-06-16 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
WO2016205200A1
(en)
|
2015-06-16 |
2016-12-22 |
Genentech, Inc. |
Anti-cll-1 antibodies and methods of use
|
MY189840A
(en)
|
2015-06-16 |
2022-03-11 |
Genentech Inc |
Humanized and affinity matured antibodies to fcrh5 and methods of use
|
MX2017016169A
(es)
|
2015-06-17 |
2018-08-15 |
Genentech Inc |
Anticuerpos anti-her2 y metodos de uso.
|
CN107810196B
(zh)
|
2015-06-24 |
2021-11-05 |
豪夫迈·罗氏有限公司 |
人源化的抗-Tau(pS422)抗体和使用方法
|
WO2017009258A1
(en)
|
2015-07-10 |
2017-01-19 |
Genmab A/S |
Axl-specific antibody-drug conjugates for cancer treatment
|
ES2812303T3
(es)
|
2015-07-10 |
2021-03-16 |
Merus Nv |
Anticuerpo que se une a CD3 humano
|
JP6878405B2
(ja)
|
2015-07-29 |
2021-05-26 |
ノバルティス アーゲー |
Pd−1に対する抗体分子を含む組み合わせ治療
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
US20180340025A1
(en)
|
2015-07-29 |
2018-11-29 |
Novartis Ag |
Combination therapies comprising antibody molecules to lag-3
|
BR112018005862A2
(pt)
|
2015-09-25 |
2018-10-16 |
Genentech, Inc. |
anticorpos, anticorpos isolados, polinucleotídeo, vetor, célula hospedeira, método de produção do anticorpo, imunoconjugado, composição, usos dos anticorpos, métodos para tratar ou retardar a progressão de um câncer e de uma doença e para aumentar, potencializar ou estimular uma resposta ou função imune e kit
|
EA037882B1
(ru)
|
2015-09-30 |
2021-05-31 |
Янссен Байотек, Инк. |
Агонистические антитела, специфически связывающие человеческий cd40, и способы их применения
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
EP3356417A1
(en)
|
2015-10-02 |
2018-08-08 |
H. Hoffnabb-La Roche Ag |
Bispecific t cell activating antigen binding molecules binding mesothelin and cd3
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
JP6734919B2
(ja)
|
2015-10-02 |
2020-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
同時結合を測定するための細胞ベースのfretアッセイ法
|
EP3356407B1
(en)
|
2015-10-02 |
2021-11-03 |
F. Hoffmann-La Roche AG |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
HRP20211594T1
(hr)
|
2015-10-02 |
2022-01-21 |
F. Hoffmann - La Roche Ag |
Anti-pd1 protutijela i načini uporabe
|
BR112018000835A2
(pt)
|
2015-10-02 |
2018-09-11 |
Hoffmann La Roche |
molécula, um ou mais polinucleotídeos, um ou mais vetores, célula, método de produção da molécula, composição, uso da molécula, método de tratamento de uma doença e método para induzir a lise de uma célula-alvo
|
US20170096495A1
(en)
|
2015-10-02 |
2017-04-06 |
Hoffmann-La Roche Inc. |
Bispecific t cell activating antigen binding molecules
|
CN108283001B
(zh)
|
2015-10-08 |
2022-08-19 |
酵活有限公司 |
包含κ和λ轻链的抗原结合多肽构建体及其用途
|
LT3365373T
(lt)
|
2015-10-23 |
2021-05-25 |
Merus N.V. |
Surišančios molekulės, kurios inhibuoja vėžio augimą
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
MX2018005036A
(es)
|
2015-10-29 |
2018-08-01 |
Hoffmann La Roche |
Anticuerpos y metodos de uso de anti-regiones de fragmentos cristalizables (fc) variantes.
|
JP6869553B2
(ja)
|
2015-10-30 |
2021-05-12 |
ギャラクシー バイオテック, エルエルシーGalaxy Biotech, Llc |
デスレセプター4及びデスレセプター5に結合する非常に強力な抗体
|
WO2017079112A1
(en)
|
2015-11-03 |
2017-05-11 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and their uses
|
JP6925278B2
(ja)
|
2015-11-18 |
2021-08-25 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
US11660340B2
(en)
|
2015-11-18 |
2023-05-30 |
Chugai Seiyaku Kabushiki Kaisha |
Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
MX2018005229A
(es)
|
2015-12-09 |
2019-04-29 |
F HoffmannLa Roche Ag |
Anticuerpo anti-cd20 de tipo ii y usos del mismo.
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Pd−1に対する抗体分子およびその使用
|
JP2019502695A
(ja)
|
2015-12-17 |
2019-01-31 |
ノバルティス アーゲー |
PD−1に対する抗体分子とC−Met阻害剤との組合せおよびその使用
|
CA3004288A1
(en)
|
2015-12-28 |
2017-07-06 |
Nobuyuki Tanaka |
Method for promoting efficiency of purification of fc region-containing polypeptide
|
CA3006529A1
(en)
|
2016-01-08 |
2017-07-13 |
F. Hoffmann-La Roche Ag |
Methods of treating cea-positive cancers using pd-1 axis binding antagonists and anti-cea/anti-cd3 bispecific antibodies
|
EP3405492B1
(en)
|
2016-01-21 |
2020-10-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
WO2017136820A2
(en)
|
2016-02-06 |
2017-08-10 |
Epimab Biotherapeutics, Inc. |
Fabs-in-tandem immunoglobulin and uses thereof
|
BR112018067679A2
(pt)
|
2016-03-04 |
2019-01-15 |
Novartis Ag |
células que expressam múltiplas moléculas do receptor de antígeno quimérico (car) e seu uso
|
SG11201807936VA
(en)
|
2016-03-14 |
2018-10-30 |
Chugai Pharmaceutical Co Ltd |
Cell injury inducing therapeutic drug for use in cancer therapy
|
JP7015244B2
(ja)
|
2016-03-22 |
2022-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
プロテアーゼ活性化t細胞二重特異性分子
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
BR112018071096A2
(pt)
|
2016-04-15 |
2019-02-26 |
Novartis Ag |
composições e métodos para a expressão da proteína seletiva
|
BR112018069890A2
(pt)
|
2016-05-02 |
2019-02-05 |
Hoffmann La Roche |
polipeptídio de fusão que se liga de forma específica a um alvo, polipeptídio de fusão dimérico, ácido nucleico isolado, par de ácidos nucleicos isolados, célula hospedeira, método para produzir um polipeptídio de fusão, imunoconjugado, formulação farmacêutica, polipeptídio de fusão e uso do polipeptídio de fusão
|
JP7359547B2
(ja)
|
2016-05-17 |
2023-10-11 |
ジェネンテック, インコーポレイテッド |
免疫療法における診断及び使用のための間質遺伝子シグネチャー
|
WO2018220099A1
(en)
|
2017-06-02 |
2018-12-06 |
F. Hoffmann-La Roche Ag |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
KR20190039929A
(ko)
|
2016-06-17 |
2019-04-16 |
제넨테크, 인크. |
다중 특이적 항체의 정제
|
JP6983824B2
(ja)
|
2016-07-04 |
2021-12-17 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
新規抗体フォーマット
|
WO2018014001A1
(en)
|
2016-07-14 |
2018-01-18 |
Fred Hutchinson Cancer Research Center |
Multiple bi-specific binding domain constructs with different epitope binding to treat cancer
|
CN110461315A
(zh)
|
2016-07-15 |
2019-11-15 |
诺华股份有限公司 |
使用与激酶抑制剂组合的嵌合抗原受体治疗和预防细胞因子释放综合征
|
SG11201900677SA
(en)
|
2016-07-28 |
2019-02-27 |
Novartis Ag |
Combination therapies of chimeric antigen receptors adn pd-1 inhibitors
|
US20190161542A1
(en)
|
2016-08-01 |
2019-05-30 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
CN109843916B
(zh)
|
2016-08-12 |
2023-10-31 |
詹森生物科技公司 |
具有增强的激动活性的Fc工程化抗TNFR超家族成员抗体及其使用方法
|
US10669344B2
(en)
|
2016-08-12 |
2020-06-02 |
Janssen Biotech, Inc. |
Engineered antibodies and other Fc-domain containing molecules with enhanced agonism and effector functions
|
CN109689682B
(zh)
|
2016-09-19 |
2022-11-29 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
WO2018060301A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies against cd3
|
CN109791149A
(zh)
|
2016-09-30 |
2019-05-21 |
豪夫迈·罗氏有限公司 |
用于功能分析多特异性分子的基于spr的双重结合测定法
|
SG10201913823VA
(en)
|
2016-10-07 |
2020-03-30 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
KR20240000650A
(ko)
|
2016-10-19 |
2024-01-02 |
인벤라 인코포레이티드 |
항체 구조물
|
MX2019005438A
(es)
|
2016-11-15 |
2019-08-16 |
Genentech Inc |
Dosificacion para tratamiento con anticuerpos bispecificos anti-cd20 / anti-cd3.
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
JP7227146B2
(ja)
|
2016-11-23 |
2023-02-21 |
バイオベラティブ セラピューティクス インコーポレイテッド |
凝固第ix因子および凝固第x因子に結合する二重特異性抗体
|
CN110087682B
(zh)
|
2016-12-19 |
2023-12-15 |
豪夫迈·罗氏有限公司 |
用靶向性4-1bb(cd137)激动剂的组合疗法
|
PL3559034T3
(pl)
|
2016-12-20 |
2021-04-19 |
F. Hoffmann-La Roche Ag |
Terapia skojarzona dwuswoistymi przeciwciałami anty-CD20/anty-CD3 i agonistami 4-1BB (CD137)
|
EP3559249A1
(en)
|
2016-12-21 |
2019-10-30 |
H. Hoffnabb-La Roche Ag |
Method for in vitro glycoengineering of antibodies
|
BR112019009839A2
(pt)
|
2016-12-21 |
2019-09-17 |
Hoffmann La Roche |
método para a produção enzimática de um anticorpo e anticorpo
|
MX2019006266A
(es)
|
2016-12-21 |
2019-08-21 |
Hoffmann La Roche |
Glucomanipulacion in vitro de anticuerpos.
|
WO2018140725A1
(en)
|
2017-01-26 |
2018-08-02 |
Novartis Ag |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
WO2018162517A1
(en)
|
2017-03-10 |
2018-09-13 |
F. Hoffmann-La Roche Ag |
Method for producing multispecific antibodies
|
WO2018177967A1
(en)
|
2017-03-27 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Improved antigen binding receptor formats
|
JP7330942B2
(ja)
|
2017-03-31 |
2023-08-22 |
ジェンマブ ホールディング ビー.ブイ. |
二重特異性抗cd37抗体、モノクローナル抗cd37抗体、およびそれらの使用方法
|
KR20190140945A
(ko)
|
2017-03-31 |
2019-12-20 |
메뤼스 엔.페. |
NRG1 융합 유전자를 가지는 세포를 치료하기 위한 ErbB-2 및 ErbB-3 결합 이중특이적 항체
|
EP3606947B1
(en)
|
2017-04-03 |
2022-12-21 |
F. Hoffmann-La Roche AG |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
KR102667951B1
(ko)
|
2017-04-03 |
2024-05-22 |
에프. 호프만-라 로슈 아게 |
Steap-1에 결합하는 항체
|
CN110506059B
(zh)
|
2017-04-05 |
2023-01-17 |
豪夫迈·罗氏有限公司 |
特异性结合pd1和lag3的双特异性抗体
|
AU2018247797A1
(en)
|
2017-04-05 |
2019-08-22 |
F. Hoffmann-La Roche Ag |
Anti-LAG3 antibodies
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
CA3061235A1
(en)
|
2017-05-18 |
2018-11-22 |
F. Hoffmann-La Roche Ag |
Reduction of application-related side reaction of a therapeutic antibody
|
MA52459A
(fr)
|
2017-06-05 |
2021-03-10 |
Janssen Biotech Inc |
Anticorps se liant spécifiquement à pd-1 et leurs méthodes d'utilisation
|
AU2018280340A1
(en)
*
|
2017-06-05 |
2019-12-19 |
The Council Of The Queensland Institute Of Medical Research |
A combination of, or a bispecific binding molecule to, an immune checkpoint molecule antagonist and a RANK-L (NF-κΒ ligand) antagonist for cancer therapy or prophylaxis and uses therefor.
|
CN111328335A
(zh)
|
2017-06-07 |
2020-06-23 |
根马布私人有限公司 |
基于突变igg六聚体的治疗性抗体
|
CU24606B1
(es)
|
2017-06-22 |
2022-06-06 |
Novartis Ag |
Moléculas de anticuerpo que se unen a cd73
|
EP3645037A1
(en)
|
2017-06-27 |
2020-05-06 |
Novartis AG |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
CA3069438A1
(en)
|
2017-07-11 |
2019-01-17 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
CN111163798A
(zh)
|
2017-07-20 |
2020-05-15 |
诺华股份有限公司 |
用于抗lag-3抗体的给药方案及其用途
|
CN111094351A
(zh)
|
2017-08-09 |
2020-05-01 |
美勒斯公司 |
结合EGFR和cMET的抗体
|
AU2018335231B2
(en)
|
2017-09-22 |
2022-03-24 |
F. Hoffmann-La Roche Ag |
Multivalent mono- or bispecific recombinant antibodies for analytic purpose
|
BR112020007154A2
(pt)
|
2017-10-20 |
2020-09-29 |
F. Hoffmann-La Roche Ag |
método para produzir um polipeptídeo e polipeptídeos heterodimérico
|
BR112020007736A2
(pt)
|
2017-10-30 |
2020-10-20 |
F. Hoffmann-La Roche Ag |
composição e método de tratamento
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
EP3704155A2
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Combination therapy with targeted ox40 agonists
|
CA3081602A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
WO2019100052A2
(en)
|
2017-11-20 |
2019-05-23 |
Compass Therapeutics Llc |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
CN111417856B
(zh)
|
2017-11-29 |
2024-05-03 |
豪夫迈·罗氏有限公司 |
抑制靶干扰作用的抗药物抗体测定法
|
AR114001A1
(es)
|
2017-12-21 |
2020-07-08 |
Hoffmann La Roche |
Anticuerpos que se unen a hla- a2 / wt1
|
CN111491951B
(zh)
|
2017-12-22 |
2024-05-24 |
豪夫迈·罗氏有限公司 |
通过疏水相互作用色谱法耗尽轻链错配的抗体变体
|
EP3731864A1
(en)
|
2017-12-29 |
2020-11-04 |
F. Hoffmann-La Roche SA |
Anti-vegf antibodies and methods of use
|
SG11202006410WA
(en)
|
2018-01-12 |
2020-08-28 |
Genzyme Corp |
Methods for the quantitation of polypeptides
|
EP3740505A1
(en)
|
2018-01-16 |
2020-11-25 |
Lakepharma Inc. |
Bispecific antibody that binds cd3 and another target
|
EP3746470A1
(en)
|
2018-01-31 |
2020-12-09 |
F. Hoffmann-La Roche AG |
Stabilized immunoglobulin domains
|
CN111655730A
(zh)
|
2018-01-31 |
2020-09-11 |
豪夫迈·罗氏有限公司 |
包含与lag3结合的抗原结合位点的双特异性抗体
|
WO2019152660A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
IL276383B2
(en)
|
2018-02-06 |
2024-01-01 |
Hoffmann La Roche |
Treatment of ophthalmological diseases
|
US11866498B2
(en)
|
2018-02-08 |
2024-01-09 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
BR112020013425A2
(pt)
|
2018-03-13 |
2020-12-01 |
F. Hoffmann-La Roche Ag |
agonista de 4-1bb (cd137), produto farmacêutico, composição farmacêutica, uso de uma combinação de um agonista de 4-1bb e um agente de direcionamento de her-2 e método para tratar ou retardar a progressão do câncer em um indivíduo
|
CN111683961A
(zh)
|
2018-03-13 |
2020-09-18 |
豪夫迈·罗氏有限公司 |
4-1bb激动剂与抗cd20抗体的治疗剂组合
|
WO2019183406A1
(en)
*
|
2018-03-21 |
2019-09-26 |
Invenra Inc. |
Multispecific antibody purification with ch1 resin
|
AU2019245243A1
(en)
|
2018-03-29 |
2020-09-03 |
Genentech, Inc |
Modulating lactogenic activity in mammalian cells
|
EP3778639A4
(en)
|
2018-04-02 |
2021-06-09 |
Mab-Venture Biopharm Co., Ltd. |
ANTIBODIES BINDING TO LYMPHOCYTAIR ACTIVATION GENE 3 (LAG-3) AND ITS USE
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
EP3794132A1
(en)
|
2018-05-18 |
2021-03-24 |
F. Hoffmann-La Roche AG |
Targeted intracellular delivery of large nucleic acids
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
US20200109195A1
(en)
|
2018-05-21 |
2020-04-09 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
JOP20200303A1
(ar)
|
2018-05-24 |
2020-11-23 |
Janssen Biotech Inc |
عوامل ربط psma واستخداماتها
|
MA52773A
(fr)
|
2018-05-24 |
2021-04-14 |
Janssen Biotech Inc |
Anticorps anti-cd3 et leurs utilisations
|
JOP20200295A1
(ar)
|
2018-05-24 |
2020-11-22 |
Janssen Biotech Inc |
أجسام أحادية النوعية ومتعددة النوعية مضادة لـ tmeff2 المضاد واستخداماتها
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
JP2021526026A
(ja)
|
2018-06-08 |
2021-09-30 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
翻訳後修飾が低減したペプチドリンカー
|
WO2019241426A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
US20210238268A1
(en)
|
2018-06-19 |
2021-08-05 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
CA3092456C
(en)
|
2018-07-25 |
2024-03-12 |
Innovent Biologics (Suzhou) Co., Ltd. |
Anti-tigit antibody and use thereof
|
CA3051549A1
(en)
|
2018-08-09 |
2020-02-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal fc receptor
|
MX2021003756A
(es)
|
2018-10-04 |
2021-08-11 |
Genmab Holding B V |
Composiciones farmaceuticas que comprenden anticuerpos anti cumulo de diferenciacion 37 (cd37) biespecificos.
|
SG11202103334YA
(en)
|
2018-10-26 |
2021-05-28 |
Hoffmann La Roche |
Multispecific antibody screening method using recombinase mediated cassette exchange
|
CA3114728C
(en)
|
2018-10-29 |
2024-05-14 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
CA3119161A1
(en)
|
2018-11-13 |
2020-05-22 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
TW202039583A
(zh)
|
2018-12-07 |
2020-11-01 |
瑞士商巴克斯歐塔有限公司 |
結合因子IXa及因子X的蛋白分子
|
WO2020114614A1
(en)
|
2018-12-07 |
2020-06-11 |
Baxalta GmbH |
Proteinaceous molecules binding factor ixa and factor x
|
WO2020115283A1
(en)
|
2018-12-07 |
2020-06-11 |
Baxalta GmbH |
Bispecific antibodies binding factor ixa and factor x
|
WO2020114615A1
(en)
|
2018-12-07 |
2020-06-11 |
Baxalta GmbH |
Bispecific antibodies binding factor ixa and factor x
|
KR20210106437A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물
|
KR20210106484A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
Hdm2-p53 상호작용 억제제와 bcl2 억제제의 조합 및 암 치료를 위한 이의 용도
|
PE20211294A1
(es)
|
2018-12-21 |
2021-07-20 |
Hoffmann La Roche |
Anticuerpo que se une a vegf y a il-1beta y metodos de utilizacion
|
MX2021007307A
(es)
|
2018-12-21 |
2021-07-07 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3.
|
US20220073630A1
(en)
|
2018-12-28 |
2022-03-10 |
Hoffmann-La Roche, Inc. |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
EP3903102B1
(en)
|
2018-12-30 |
2023-04-12 |
F. Hoffmann-La Roche AG |
Ph-gradient spr-based binding assay
|
EP3924054A1
(en)
|
2019-02-15 |
2021-12-22 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
WO2020174370A2
(en)
|
2019-02-26 |
2020-09-03 |
Janssen Biotech, Inc. |
Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
|
CN113631578A
(zh)
|
2019-03-14 |
2021-11-09 |
豪夫迈·罗氏有限公司 |
用her2xcd3双特异性抗体联合抗her2 mab治疗癌症
|
WO2020205523A1
(en)
|
2019-03-29 |
2020-10-08 |
Atarga, Llc |
Anti fgf23 antibody
|
EP3947440A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Method for generating avid-binding multispecific antibodies
|
JP7249432B2
(ja)
|
2019-03-29 |
2023-03-30 |
エフ. ホフマン-ラ ロシュ アーゲー |
多価分子の機能分析のための、sprをベースとする結合アッセイ
|
WO2020227457A1
(en)
|
2019-05-08 |
2020-11-12 |
Janssen Biotech, Inc. |
Materials and methods for modulating t cell mediated immunity
|
CA3139402A1
(en)
|
2019-05-09 |
2020-11-12 |
Merus N.V. |
Variant domains for multimerizing proteins and separation thereof
|
KR20220005568A
(ko)
|
2019-05-09 |
2022-01-13 |
제넨테크, 인크. |
항체의 제조 방법
|
WO2020229378A1
(en)
|
2019-05-13 |
2020-11-19 |
F. Hoffmann-La Roche Ag |
Interference-suppressed pharmacokinetic immunoassay
|
US11879013B2
(en)
|
2019-05-14 |
2024-01-23 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
|
WO2020254356A1
(en)
|
2019-06-19 |
2020-12-24 |
F. Hoffmann-La Roche Ag |
Method for the generation of a multivalent, bispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
KR20220024636A
(ko)
|
2019-06-19 |
2022-03-03 |
에프. 호프만-라 로슈 아게 |
정의된 조직의 다수 발현 카세트들의 표적화 통합에 의한 다가, 다중특이성 항체 발현 세포의 생성 방법
|
EP3986928A1
(en)
|
2019-06-19 |
2022-04-27 |
F. Hoffmann-La Roche AG |
Method for the generation of a protein expressing cell by targeted integration using cre mrna
|
JP2022537338A
(ja)
|
2019-06-19 |
2022-08-25 |
エフ.ホフマン-ラ ロシュ アーゲー |
所定の構成の複数の発現カセットの標的指向性組込みによって二価二重特異性抗体発現細胞を作製するための方法
|
CA3140287A1
(en)
|
2019-06-19 |
2020-12-24 |
Johannes Auer |
Method for the generation of a trivalent antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
MX2021015823A
(es)
|
2019-06-26 |
2022-02-03 |
Hoffmann La Roche |
Lineas celulares de mamifero con inactivacion del gen sirtuina-1 (sirt-1).
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
WO2021018925A1
(en)
|
2019-07-31 |
2021-02-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to gprc5d
|
EP4003526A2
(en)
|
2019-07-31 |
2022-06-01 |
F. Hoffmann-La Roche AG |
Antibodies binding to gprc5d
|
CR20220156A
(es)
|
2019-09-18 |
2022-05-23 |
Genentech Inc |
Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5/klk7 y métodos de uso
|
CA3157665A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Tim-3 inhibitors and uses thereof
|
BR112022007376A2
(pt)
|
2019-10-21 |
2022-07-05 |
Novartis Ag |
Terapias de combinação com venetoclax e inibidores de tim-3
|
BR112022008172A2
(pt)
|
2019-11-15 |
2022-07-12 |
Hoffmann La Roche |
Composição aquosa estável, método para obter uma composição e forma de dosagem farmacêutica
|
BR112022010206A2
(pt)
|
2019-11-26 |
2022-11-29 |
Novartis Ag |
Receptores de antígeno quiméricos e usos dos mesmos
|
JP2023506162A
(ja)
*
|
2019-12-10 |
2023-02-15 |
エービーエル バイオ インコーポレイテッド |
抗bcma/抗4-1bb二重特異性抗体及びその用途
|
EP4072584A1
(en)
|
2019-12-13 |
2022-10-19 |
Genentech, Inc. |
Anti-ly6g6d antibodies and methods of use
|
BR112022012010A2
(pt)
|
2019-12-18 |
2022-08-30 |
Hoffmann La Roche |
Anticorpos, ácido nucleico isolado, célula hospedeira, formulação farmacêutica, uso do anticorpo, método de produção de um anticorpo, método de tratamento de um indivíduo que tem câncer e método de tratamento de um indivíduo que tem uma doença inflamatória ou autoimune
|
AU2020406085A1
(en)
|
2019-12-18 |
2022-05-26 |
F. Hoffmann-La Roche Ag |
Antibodies binding to HLA-A2/MAGE-A4
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
KR20220118527A
(ko)
|
2019-12-23 |
2022-08-25 |
제넨테크, 인크. |
아포지질단백질 l1-특이적 항체 및 이용 방법
|
EP4085251A1
(en)
|
2020-01-02 |
2022-11-09 |
F. Hoffmann-La Roche AG |
Method for determining the amount of a therapeutic antibody in the brain
|
JP2023510382A
(ja)
|
2020-01-15 |
2023-03-13 |
エフ. ホフマン-ラ ロシュ アーゲー |
組換えタンパク質製造プロセスから不純物を減少させる方法
|
US20210222244A1
(en)
|
2020-01-17 |
2021-07-22 |
Becton, Dickinson And Company |
Methods and compositions for single cell secretomics
|
CN114980902A
(zh)
|
2020-01-17 |
2022-08-30 |
诺华股份有限公司 |
用于治疗骨髓增生异常综合征或慢性粒单核细胞白血病的包含tim-3抑制剂和低甲基化药物的组合
|
BR112022016633A2
(pt)
|
2020-02-27 |
2022-12-13 |
Novartis Ag |
Métodos para produzir células que expressam receptor de antígeno quimérico
|
US11879004B2
(en)
|
2020-02-28 |
2024-01-23 |
Genzyme Corporation |
Modified binding polypeptides for optimized drug conjugation
|
US20230126689A1
(en)
|
2020-03-06 |
2023-04-27 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
EP4127153A2
(en)
|
2020-03-26 |
2023-02-08 |
Genentech, Inc. |
Modified mammalian cells having reduced host cell proteins
|
CN115397850A
(zh)
|
2020-03-30 |
2022-11-25 |
豪夫迈·罗氏有限公司 |
与vegf和pdgf-b结合的抗体及其使用方法
|
CN115605184A
(zh)
|
2020-05-15 |
2023-01-13 |
豪夫迈·罗氏有限公司(Ch) |
防止胃肠外蛋白质溶液中的可见颗粒形成
|
WO2021233853A1
(en)
|
2020-05-19 |
2021-11-25 |
F. Hoffmann-La Roche Ag |
The use of chelators for the prevention of visible particle formation in parenteral protein solutions
|
IL298394A
(en)
|
2020-05-21 |
2023-01-01 |
Merus Nv |
Methods and means for producing ig-like molecules
|
AR122569A1
(es)
|
2020-06-08 |
2022-09-21 |
Hoffmann La Roche |
Anticuerpos anti-vhb y métodos de uso
|
IL298923A
(en)
|
2020-06-16 |
2023-02-01 |
Hoffmann La Roche |
A method for determining the free antigen of an antibody in a sample
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
TWI811703B
(zh)
|
2020-06-19 |
2023-08-11 |
瑞士商赫孚孟拉羅股份公司 |
與cd3及cd19結合之抗體
|
BR112022025809A2
(pt)
|
2020-06-19 |
2023-01-10 |
Hoffmann La Roche |
Anticorpos, polinucleotídeo isolado, célula hospedeira, método para produzir um anticorpo, uso do anticorpo, método para tratar uma doença e invenção
|
MX2022015204A
(es)
|
2020-06-19 |
2023-01-05 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3.
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
MX2022016453A
(es)
|
2020-06-24 |
2023-02-01 |
Genentech Inc |
Lineas celulares resistentes a la apoptosis.
|
CN116133689A
(zh)
|
2020-07-07 |
2023-05-16 |
豪夫迈·罗氏有限公司 |
作为治疗性蛋白质制剂的稳定剂的替代表面活性剂
|
PE20231093A1
(es)
|
2020-07-16 |
2023-07-18 |
Novartis Ag |
Anticuerpos anti-betacelulina, fragmentos de los mismos, y moleculas de union multiespecificas
|
JP2023534458A
(ja)
|
2020-07-17 |
2023-08-09 |
ジェネンテック, インコーポレイテッド |
抗Notch2抗体及び使用方法
|
BR112023001209A2
(pt)
|
2020-07-24 |
2023-02-14 |
Hoffmann La Roche |
Método para produzir um polipeptídeo de fusão-anticorpo-multímero
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
CA3192344A1
(en)
|
2020-08-28 |
2022-03-03 |
Genentech, Inc. |
Crispr/cas9 multiplex knockout of host cell proteins
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
MX2023002496A
(es)
|
2020-09-04 |
2023-03-09 |
Hoffmann La Roche |
Anticuerpo que se une al factor de crecimiento endotelial vascular a (vegf-a) y a la angiopoyetina 2 (ang2) y metodos de uso.
|
CA3191328A1
(en)
|
2020-09-21 |
2022-03-24 |
Genentech, Inc. |
Purification of multispecific antibodies
|
MX2023003328A
(es)
|
2020-09-24 |
2023-03-27 |
Hoffmann La Roche |
Lineas de celulas de mamifero con desactivacion genica.
|
TWI836278B
(zh)
|
2020-10-05 |
2024-03-21 |
美商建南德克公司 |
用抗fcrh5/抗cd3雙特異性抗體進行治療之給藥
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg結合抗mertk抗體及其使用方法
|
EP4240765A2
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Antibody fc variants
|
IL302700A
(en)
|
2020-11-13 |
2023-07-01 |
Novartis Ag |
Combined treatments with cells expressing chimeric antigens (vehicle)
|
KR20220082775A
(ko)
|
2020-12-10 |
2022-06-17 |
주식회사 유틸렉스 |
항-pd-1 항체 및 이의 용도
|
US20220213199A1
(en)
|
2020-12-17 |
2022-07-07 |
Hoffmann-La Roche Inc. |
Anti-HLA-G antibodies and use thereof
|
EP4267734A1
(en)
|
2020-12-22 |
2023-11-01 |
F. Hoffmann-La Roche AG |
Oligonucleotides targeting xbp1
|
EP4269435A1
(en)
|
2020-12-23 |
2023-11-01 |
Innovent Biologics (Singapore) Pte. Ltd. |
Anti-b7-h3 antibody and uses thereof
|
CN114716548A
(zh)
|
2021-01-05 |
2022-07-08 |
(株)爱恩德生物 |
抗-fgfr3抗体及其用途
|
KR20230117406A
(ko)
|
2021-01-06 |
2023-08-08 |
에프. 호프만-라 로슈 아게 |
Pd1-lag3 이중특이성 항체와 cd20 t 세포 이중특이성항체를 이용한 조합 요법
|
WO2022162518A2
(en)
|
2021-01-28 |
2022-08-04 |
Janssen Biotech, Inc. |
Psma binding proteins and uses thereof
|
US20240141060A1
(en)
|
2021-01-29 |
2024-05-02 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
US20240101673A1
(en)
|
2021-02-03 |
2024-03-28 |
Mozart Therapeutics, Inc. |
Binding agents and methods of using the same
|
JP2024509695A
(ja)
|
2021-02-03 |
2024-03-05 |
ジェネンテック, インコーポレイテッド |
多重特異性結合タンパク質分解プラットフォームおよび使用方法
|
CA3209827A1
(en)
|
2021-02-04 |
2022-08-11 |
Innovent Biologics (Suzhou) Co., Ltd. |
Anti-tnfr2 antibody and use thereof
|
WO2022175217A1
(en)
|
2021-02-18 |
2022-08-25 |
F. Hoffmann-La Roche Ag |
Method for resolving complex, multistep antibody interactions
|
JP2024512324A
(ja)
|
2021-03-05 |
2024-03-19 |
ジーオー セラピューティクス,インコーポレイテッド |
抗グリコcd44抗体およびその使用
|
AU2022233518A1
(en)
|
2021-03-09 |
2023-10-26 |
Janssen Biotech, Inc. |
Treatment of cancers lacking egfr-activating mutations
|
WO2022192647A1
(en)
|
2021-03-12 |
2022-09-15 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
JP2024513474A
(ja)
|
2021-04-09 |
2024-03-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
異種ポリペプチドを発現する細胞クローンを選択するための方法
|
WO2022217022A1
(en)
|
2021-04-10 |
2022-10-13 |
Profoundbio Us Co. |
Folr1 binding agents, conjugates thereof and methods of using the same
|
KR20230173164A
(ko)
|
2021-04-19 |
2023-12-26 |
제넨테크, 인크. |
변형된 포유류 세포
|
TW202308699A
(zh)
|
2021-04-23 |
2023-03-01 |
美商普方生物製藥美國公司 |
Cd70結合劑、其結合物及其使用方法
|
KR20240005722A
(ko)
|
2021-04-30 |
2024-01-12 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이적 항체를 사용한 치료를 위한 투약
|
JP2024517535A
(ja)
|
2021-04-30 |
2024-04-23 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗cd20/抗cd3二重特異性抗体と抗cd79b抗体薬物コンジュゲートを用いた併用治療の投与
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
CN117396599A
(zh)
|
2021-05-21 |
2024-01-12 |
基因泰克公司 |
用于生产目的重组产物的经修饰的细胞
|
US20230077531A1
(en)
|
2021-05-27 |
2023-03-16 |
Sanofi |
Fc VARIANT WITH ENHANCED AFFINITY TO Fc RECEPTORS AND IMPROVED THERMAL STABILITY
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
EP4346885A1
(en)
*
|
2021-05-28 |
2024-04-10 |
Julius-Maximilians-Universität Würzburg |
Recombinant proteinaceous binding molecules
|
AU2022295067A1
(en)
|
2021-06-18 |
2023-12-21 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ccl2 antibodies
|
AU2022302170A1
(en)
|
2021-07-02 |
2023-12-21 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating cancer
|
US20230197278A1
(en)
|
2021-07-13 |
2023-06-22 |
Genentech, Inc. |
Multi-variate model for predicting cytokine release syndrome
|
WO2023001884A1
(en)
|
2021-07-22 |
2023-01-26 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
KR20240038008A
(ko)
|
2021-07-28 |
2024-03-22 |
에프. 호프만-라 로슈 아게 |
암 치료 방법 및 조성물
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
AU2022324456A1
(en)
|
2021-08-05 |
2024-02-15 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
WO2023034569A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-cmet antibodies and their uses
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
WO2023034571A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-lamp1 antibodies and their uses
|
EP4148067A1
(en)
|
2021-09-08 |
2023-03-15 |
F. Hoffmann-La Roche AG |
Method for the expression of an antibody-multimer-fusion
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
WO2023094282A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Quantification of low amounts of antibody sideproducts
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
WO2023117325A1
(en)
|
2021-12-21 |
2023-06-29 |
F. Hoffmann-La Roche Ag |
Method for the determination of hydrolytic activity
|
AU2022424002A1
(en)
|
2021-12-29 |
2024-06-13 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
WO2023141445A1
(en)
|
2022-01-19 |
2023-07-27 |
Genentech, Inc. |
Anti-notch2 antibodies and conjugates and methods of use
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用egfr/met雙特異性抗體治療之患者的輸注相關反應之方法
|
WO2023150778A1
(en)
|
2022-02-07 |
2023-08-10 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
WO2023180353A1
(en)
|
2022-03-23 |
2023-09-28 |
F. Hoffmann-La Roche Ag |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
TW202346337A
(zh)
|
2022-03-29 |
2023-12-01 |
美商恩格姆生物製藥公司 |
Ilt3及cd3結合劑以及其使用方法
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
JP2024517042A
(ja)
|
2022-04-13 |
2024-04-19 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗cd20/抗cd3二重特異性抗体の薬学的組成物及び使用方法
|
WO2023201299A1
(en)
|
2022-04-13 |
2023-10-19 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
TW202402810A
(zh)
|
2022-05-11 |
2024-01-16 |
瑞士商赫孚孟拉羅股份公司 |
與vegf—a及il6結合之抗體及其使用方法
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
WO2023218431A1
(en)
|
2022-05-13 |
2023-11-16 |
BioNTech SE |
Rna compositions targeting hiv
|
WO2023227790A1
(en)
|
2022-05-27 |
2023-11-30 |
Sanofi |
Natural killer (nk) cell engagers binding to nkp46 and bcma variants with fc-engineering
|
WO2023232961A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2024003837A1
(en)
|
2022-06-30 |
2024-01-04 |
Janssen Biotech, Inc. |
Use of anti-egfr/anti-met antibody to treat gastric or esophageal cancer
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020564A1
(en)
|
2022-07-22 |
2024-01-25 |
Genentech, Inc. |
Anti-steap1 antigen-binding molecules and uses thereof
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
WO2024030976A2
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
Compositions and methods for crossing the blood brain barrier
|
WO2024079074A1
(en)
|
2022-10-10 |
2024-04-18 |
Universite D'aix Marseille |
ANTI-sCD146 ANTIBODIES AND USES THEREOF
|
WO2024079010A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and cd38 antibodies
|
WO2024079009A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and proteasome inhibitors
|
WO2024079015A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and imids
|
WO2024079069A1
(en)
|
2022-10-12 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Method for classifying cells
|
US20240166750A1
(en)
|
2022-10-25 |
2024-05-23 |
Ablynx N.V. |
GLYCOENGINEERED Fc VARIANT POLYPEPTIDES WITH ENHANCED EFFECTOR FUNCTION
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
WO2024094741A1
(en)
|
2022-11-03 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Combination therapy with anti-cd19/anti-cd28 bispecific antibody
|
WO2024110426A1
(en)
|
2022-11-23 |
2024-05-30 |
F. Hoffmann-La Roche Ag |
Method for increasing recombinant protein expression
|