BR112015000665A2 - método para a determinação da quantidade de um anticorpo - Google Patents
método para a determinação da quantidade de um anticorpoInfo
- Publication number
- BR112015000665A2 BR112015000665A2 BR112015000665A BR112015000665A BR112015000665A2 BR 112015000665 A2 BR112015000665 A2 BR 112015000665A2 BR 112015000665 A BR112015000665 A BR 112015000665A BR 112015000665 A BR112015000665 A BR 112015000665A BR 112015000665 A2 BR112015000665 A2 BR 112015000665A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- determining
- amount
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/686—Anti-idiotype
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12176342 | 2012-07-13 | ||
PCT/EP2013/064683 WO2014009474A1 (en) | 2012-07-13 | 2013-07-11 | Method for the detection of a multispecific binder |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015000665A2 true BR112015000665A2 (pt) | 2017-06-27 |
Family
ID=48782335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015000665A BR112015000665A2 (pt) | 2012-07-13 | 2013-07-11 | método para a determinação da quantidade de um anticorpo |
Country Status (12)
Country | Link |
---|---|
US (1) | US9488662B2 (pt) |
EP (1) | EP2872893B1 (pt) |
JP (1) | JP6226976B2 (pt) |
KR (1) | KR20150038046A (pt) |
CN (1) | CN104471397B (pt) |
BR (1) | BR112015000665A2 (pt) |
CA (1) | CA2873829A1 (pt) |
ES (1) | ES2627482T3 (pt) |
HK (1) | HK1208731A1 (pt) |
MX (1) | MX346146B (pt) |
RU (1) | RU2636822C2 (pt) |
WO (1) | WO2014009474A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2620563C2 (ru) | 2012-02-01 | 2017-05-26 | Ф. Хоффманн-Ля Рош Аг | Способ детекции партнера по связыванию мультиспецифического связывающего агента |
JP6446044B2 (ja) * | 2013-11-05 | 2018-12-26 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 |
EP3136096B1 (en) | 2014-04-23 | 2021-12-01 | Nichirei Biosciences Inc. | Combination for target marker detection |
AU2016344665C1 (en) * | 2015-10-29 | 2023-07-27 | F. Hoffmann-La Roche Ag | Anti-variant Fc-region antibodies and methods of use |
BR112018008789A2 (pt) * | 2015-11-30 | 2018-10-30 | F. Hoffmann-La Roche Ag | método para a determinação da quantidade de um anticorpo bivalente em uma amostra de soro ou plasma |
WO2019235420A1 (ja) | 2018-06-04 | 2019-12-12 | 中外製薬株式会社 | 複合体を検出する方法 |
EP3969907A1 (en) * | 2019-05-13 | 2022-03-23 | F. Hoffmann-La Roche AG | Interference-suppressed pharmacokinetic immunoassay |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219730A (en) | 1982-09-28 | 1993-06-15 | New York University | Idiotype-anti-idiotype immunoassay |
US4828981A (en) | 1983-08-24 | 1989-05-09 | Synbiotics Corporation | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents |
EP0170302A1 (fr) | 1984-06-27 | 1986-02-05 | l'Association internationale à but scientifique, dite: Institut international de pathologie cellulaire et moléculaire | Procédé de dosage immunologique d'une substance dans un échantillon liquide au moyen d'anticorps anti-idiotypiques |
US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
EP0243471A4 (en) | 1985-10-22 | 1989-07-11 | Cooper Lipotech Inc | SOLID PHASE LIPOSOME IMMUNOANALYSIS SYSTEM. |
US5068088A (en) | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
SG60022A1 (en) | 1988-11-03 | 1999-02-22 | Igen Inc | Electrochemicalmiliuminescent assays |
IL100866A (en) | 1991-02-06 | 1995-10-31 | Igen Inc | Luminescence test method and device based on magnetic tiny particles, containing many magnets |
DK0651761T3 (da) | 1992-07-13 | 2003-02-10 | Bionebraska Inc | Fremgangsmåde til modifikation af rekombinante polypeptider |
GB9316369D0 (en) | 1993-08-06 | 1993-09-22 | Surface Active Ltd | Diagnostic method |
US6753189B1 (en) | 1998-06-04 | 2004-06-22 | Mizuho Medy Co., Ltd. | Detection apparatus and method for the same |
AU774575C (en) | 1999-11-16 | 2005-09-08 | Genentech Inc. | Elisa for VEGF |
DE60233744D1 (de) | 2001-09-20 | 2009-10-29 | Univ Texas | Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests |
US20080206782A1 (en) | 2005-03-08 | 2008-08-28 | Genentech, Inc. | Methods for Determining the Bivalency of Protein and Antibody Therapeutics |
PT2069798E (pt) | 2006-10-04 | 2014-06-24 | Genentech Inc | Elisa para vegf |
EP1917854A1 (en) | 2006-11-06 | 2008-05-07 | F. Hoffmann-La Roche Ag | Method for producing anti idiotypic antibodies |
AU2008234248C1 (en) | 2007-03-29 | 2015-01-22 | Genmab A/S | Bispecific antibodies and methods for production thereof |
TWI570135B (zh) * | 2007-04-27 | 2017-02-11 | 建南德克公司 | 高效、穩定且非免疫抑制之抗-cd4抗體 |
US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
US8227577B2 (en) | 2007-12-21 | 2012-07-24 | Hoffman-La Roche Inc. | Bivalent, bispecific antibodies |
US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
WO2010042031A1 (en) * | 2008-10-07 | 2010-04-15 | Gyros Patent Ab | Semi-sequential assay for detection of an analyte in a sample |
US8268314B2 (en) * | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
CN102369215B (zh) | 2009-04-02 | 2015-01-21 | 罗切格利卡特公司 | 包含全长抗体和单链Fab片段的多特异性抗体 |
PT2417156E (pt) | 2009-04-07 | 2015-04-29 | Roche Glycart Ag | Anticorpos trivalentes, biespecíficos |
SG176219A1 (en) | 2009-05-27 | 2011-12-29 | Hoffmann La Roche | Tri- or tetraspecific antibodies |
US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
US8703132B2 (en) | 2009-06-18 | 2014-04-22 | Hoffmann-La Roche, Inc. | Bispecific, tetravalent antigen binding proteins |
CN102207504A (zh) | 2011-03-23 | 2011-10-05 | 北京华创远航科技有限公司 | 一种酶联检测试剂盒及其制备方法 |
CN104040350B (zh) | 2011-12-19 | 2016-05-18 | 弗·哈夫曼-拉罗切有限公司 | 用于检测多特异性结合物的游离结合搭档的方法 |
RU2620563C2 (ru) | 2012-02-01 | 2017-05-26 | Ф. Хоффманн-Ля Рош Аг | Способ детекции партнера по связыванию мультиспецифического связывающего агента |
-
2013
- 2013-07-11 WO PCT/EP2013/064683 patent/WO2014009474A1/en active Application Filing
- 2013-07-11 EP EP13735290.2A patent/EP2872893B1/en active Active
- 2013-07-11 CN CN201380036820.XA patent/CN104471397B/zh active Active
- 2013-07-11 KR KR1020157003608A patent/KR20150038046A/ko not_active Application Discontinuation
- 2013-07-11 JP JP2015520992A patent/JP6226976B2/ja active Active
- 2013-07-11 MX MX2014014566A patent/MX346146B/es active IP Right Grant
- 2013-07-11 ES ES13735290.2T patent/ES2627482T3/es active Active
- 2013-07-11 RU RU2015104737A patent/RU2636822C2/ru not_active IP Right Cessation
- 2013-07-11 CA CA2873829A patent/CA2873829A1/en not_active Abandoned
- 2013-07-11 BR BR112015000665A patent/BR112015000665A2/pt not_active Application Discontinuation
-
2015
- 2015-01-15 US US14/597,913 patent/US9488662B2/en active Active
- 2015-09-24 HK HK15109419.7A patent/HK1208731A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MX2014014566A (es) | 2015-02-20 |
EP2872893A1 (en) | 2015-05-20 |
US20150198608A1 (en) | 2015-07-16 |
JP2015522171A (ja) | 2015-08-03 |
WO2014009474A1 (en) | 2014-01-16 |
US9488662B2 (en) | 2016-11-08 |
RU2636822C2 (ru) | 2017-11-28 |
MX346146B (es) | 2017-03-09 |
KR20150038046A (ko) | 2015-04-08 |
CN104471397A (zh) | 2015-03-25 |
CA2873829A1 (en) | 2014-01-16 |
HK1208731A1 (en) | 2016-03-11 |
RU2015104737A (ru) | 2016-08-27 |
CN104471397B (zh) | 2018-03-23 |
ES2627482T3 (es) | 2017-07-28 |
EP2872893B1 (en) | 2017-03-29 |
JP6226976B2 (ja) | 2017-11-08 |
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Legal Events
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B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
B06I | Technical and formal requirements: publication cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
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B07D | Technical examination (opinion) related to article 229 of industrial property law |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
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B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure | ||
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 7A ANUIDADE. |
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B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |