MA52773A - Anticorps anti-cd3 et leurs utilisations - Google Patents
Anticorps anti-cd3 et leurs utilisationsInfo
- Publication number
- MA52773A MA52773A MA052773A MA52773A MA52773A MA 52773 A MA52773 A MA 52773A MA 052773 A MA052773 A MA 052773A MA 52773 A MA52773 A MA 52773A MA 52773 A MA52773 A MA 52773A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862676081P | 2018-05-24 | 2018-05-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA52773A true MA52773A (fr) | 2021-04-14 |
Family
ID=67211773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA052773A MA52773A (fr) | 2018-05-24 | 2019-05-21 | Anticorps anti-cd3 et leurs utilisations |
Country Status (25)
Country | Link |
---|---|
US (2) | US11603405B2 (fr) |
EP (1) | EP3802608A2 (fr) |
JP (1) | JP2021524249A (fr) |
KR (1) | KR20210012007A (fr) |
CN (1) | CN112912397A (fr) |
AR (1) | AR115422A1 (fr) |
AU (1) | AU2019274656A1 (fr) |
BR (1) | BR112020023508A2 (fr) |
CA (1) | CA3101271A1 (fr) |
CL (1) | CL2020003033A1 (fr) |
CO (1) | CO2020014506A2 (fr) |
CR (1) | CR20200568A (fr) |
EA (1) | EA202092847A1 (fr) |
EC (1) | ECSP20075215A (fr) |
IL (1) | IL278846A (fr) |
JO (1) | JOP20200302A1 (fr) |
MA (1) | MA52773A (fr) |
MX (1) | MX2020012587A (fr) |
NI (1) | NI202000089A (fr) |
PE (1) | PE20210132A1 (fr) |
PH (1) | PH12020551920A1 (fr) |
SG (1) | SG11202011270QA (fr) |
TW (1) | TW202012443A (fr) |
UY (1) | UY38245A (fr) |
WO (1) | WO2019224717A2 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11713358B2 (en) | 2015-08-28 | 2023-08-01 | Amunix Pharmaceuticals, Inc. | Chimeric polypeptide assembly and methods of making and using the same |
JP2020527332A (ja) | 2017-06-12 | 2020-09-10 | ブルーフィン バイオメディシン, インコーポレイテッド | 抗−il1rap抗体および抗体薬物コンジュゲート |
EA202092839A1 (ru) | 2018-05-24 | 2021-02-12 | Янссен Байотек, Инк. | Агенты, связывающиеся с psma, и виды их применения |
EP3802607A2 (fr) | 2018-05-24 | 2021-04-14 | Janssen Biotech, Inc. | Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations |
JOP20190116A1 (ar) * | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها |
EP3823664A1 (fr) * | 2018-07-19 | 2021-05-26 | Regeneron Pharmaceuticals, Inc. | Anticorps anti-bcma x anti-cd3 bispécifiques et leurs utilisations |
JP2022529985A (ja) | 2019-04-19 | 2022-06-27 | ヤンセン バイオテツク,インコーポレーテツド | 抗psma/cd3抗体で前立腺癌を治療する方法 |
WO2021019389A1 (fr) | 2019-07-26 | 2021-02-04 | Janssen Biotech, Inc. | Protéines comprenant des domaines de liaison à l'antigène de peptidase 2 liée à la kallicréine et leurs utilisations |
CN116249714A (zh) * | 2020-05-27 | 2023-06-09 | 詹森生物科技公司 | 包含cd3抗原结合结构域的蛋白质及其用途 |
TW202221028A (zh) | 2020-07-29 | 2022-06-01 | 美商健生生物科技公司 | 包括hla-g抗原結合域之蛋白及其用途 |
CA3194771A1 (fr) | 2020-09-16 | 2022-03-24 | Amgen Inc. | Methodes d'administration de doses therapeutiques de molecules bispecifiques activant les lymphocytes t pour le traitement du cancer |
WO2022084915A1 (fr) | 2020-10-22 | 2022-04-28 | Janssen Biotech, Inc. | Protéines comprenant des domaines de liaison à l'antigène du ligand 3 de type delta et leurs utilisations |
US20230073821A1 (en) * | 2021-08-27 | 2023-03-09 | International Business Machines Corporation | Antigen-binding proteins targeting coronavirus (cov) variants |
WO2023178645A1 (fr) * | 2022-03-25 | 2023-09-28 | 嘉和生物药业有限公司 | Anticorps ciblant cd3 et son utilisation |
WO2024062074A1 (fr) * | 2022-09-21 | 2024-03-28 | Sanofi Biotechnology | Anticorps anti-il-1r3 humanisé et procédés d'utilisation |
WO2024077044A1 (fr) | 2022-10-05 | 2024-04-11 | Amgen Inc. | Polythérapies comprenant des thérapies de redirection de lymphocytes t et des anticorps agonistes anti-il-2r ou des fragments de ceux-ci |
WO2024089551A1 (fr) | 2022-10-25 | 2024-05-02 | Janssen Biotech, Inc. | Agents de liaison msln et cd3 et leurs méthodes d'utilisation |
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US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
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US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
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WO1993011236A1 (fr) | 1991-12-02 | 1993-06-10 | Medical Research Council | Production d'anticorps anti-auto-antigenes a partir de repertoires de segments d'anticorps affiches sur phage |
JP3720353B2 (ja) | 1992-12-04 | 2005-11-24 | メディカル リサーチ カウンシル | 多価および多重特異性の結合タンパク質、それらの製造および使用 |
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US6818749B1 (en) | 1998-10-31 | 2004-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Variants of humanized anti carcinoma monoclonal antibody cc49 |
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EP3050963B1 (fr) | 2005-03-31 | 2019-09-18 | Chugai Seiyaku Kabushiki Kaisha | Procédé pour la production de polypeptide au moyen de la régulation d'un ensemble |
DE102005028778A1 (de) | 2005-06-22 | 2006-12-28 | SUNJÜT Deutschland GmbH | Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage |
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JP2009541275A (ja) | 2006-06-22 | 2009-11-26 | ノボ・ノルデイスク・エー/エス | 二重特異性抗体の生産 |
JP2010535032A (ja) | 2007-07-31 | 2010-11-18 | メディミューン,エルエルシー | 多重特異性エピトープ結合性タンパク質およびその用途 |
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PL2714733T4 (pl) | 2011-05-21 | 2019-08-30 | Macrogenics, Inc. | Cząsteczki wiążące CD3 zdolne do wiązania z ludzkim i nieludzkim CD3 |
WO2013063702A1 (fr) | 2011-11-04 | 2013-05-10 | Zymeworks Inc. | Structure d'anticorps hétérodimérique stable comprenant des mutations dans le domaine fc |
JOP20200236A1 (ar) * | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
PT3653049T (pt) | 2012-12-14 | 2023-11-14 | Omniab Inc | Polinucleótidos que codificam anticorpos de roedores com idiótipos humanos e animais que os compreendem |
WO2015001085A1 (fr) * | 2013-07-05 | 2015-01-08 | Genmab B.V. | Anticorps anti-cd3 humanisés ou chimères |
PE20210107A1 (es) * | 2013-12-17 | 2021-01-19 | Genentech Inc | Anticuerpos anti-cd3 y metodos de uso |
EP3763739A1 (fr) * | 2014-05-28 | 2021-01-13 | F. Hoffmann-La Roche AG | Anticorps se liant aux cd3 epsilon humains et cynomolgus |
EP2982693A1 (fr) * | 2014-08-07 | 2016-02-10 | Affimed Therapeutics AG | Domaine de liaison CD3 |
TW202130662A (zh) * | 2015-01-23 | 2021-08-16 | 法商賽諾菲公司 | 特異性結合cd3及/或cd123之抗—cd3抗體,抗—cd123抗體及雙特異性抗體 |
MX2018005545A (es) | 2015-11-02 | 2019-02-20 | Janssen Pharmaceutica Nv | Anticuerpos anti-il1rap, moleculas de union a antigenos biespecificas que se unen a il1rap y cd3, y usos de estas. |
KR20230035706A (ko) | 2016-09-14 | 2023-03-14 | 테네오원, 인코포레이티드 | Cd3 결합 항체 |
JOP20200292A1 (ar) * | 2018-05-16 | 2020-11-15 | Stichting Vumc | Bcma / cd3 و gprdc5d / cd3 مضادات غير محددة للاستخدام في علاج السرطان |
EP3802607A2 (fr) | 2018-05-24 | 2021-04-14 | Janssen Biotech, Inc. | Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations |
JOP20190116A1 (ar) | 2018-05-24 | 2019-11-24 | Janssen Biotech Inc | الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها |
EA202092839A1 (ru) | 2018-05-24 | 2021-02-12 | Янссен Байотек, Инк. | Агенты, связывающиеся с psma, и виды их применения |
-
2019
- 2019-05-21 JO JOP/2020/0302A patent/JOP20200302A1/ar unknown
- 2019-05-21 EP EP19737219.6A patent/EP3802608A2/fr active Pending
- 2019-05-21 MA MA052773A patent/MA52773A/fr unknown
- 2019-05-21 MX MX2020012587A patent/MX2020012587A/es unknown
- 2019-05-21 CN CN201980049271.7A patent/CN112912397A/zh active Pending
- 2019-05-21 CA CA3101271A patent/CA3101271A1/fr active Pending
- 2019-05-21 KR KR1020207037046A patent/KR20210012007A/ko unknown
- 2019-05-21 JP JP2020565282A patent/JP2021524249A/ja active Pending
- 2019-05-21 BR BR112020023508-3A patent/BR112020023508A2/pt unknown
- 2019-05-21 CR CR20200568A patent/CR20200568A/es unknown
- 2019-05-21 WO PCT/IB2019/054188 patent/WO2019224717A2/fr unknown
- 2019-05-21 US US16/418,082 patent/US11603405B2/en active Active
- 2019-05-21 AU AU2019274656A patent/AU2019274656A1/en active Pending
- 2019-05-21 PE PE2020001886A patent/PE20210132A1/es unknown
- 2019-05-21 EA EA202092847A patent/EA202092847A1/ru unknown
- 2019-05-21 SG SG11202011270QA patent/SG11202011270QA/en unknown
- 2019-05-24 UY UY0001038245A patent/UY38245A/es unknown
- 2019-05-24 TW TW108118086A patent/TW202012443A/zh unknown
- 2019-05-24 AR ARP190101400A patent/AR115422A1/es unknown
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2020
- 2020-11-09 PH PH12020551920A patent/PH12020551920A1/en unknown
- 2020-11-19 IL IL278846A patent/IL278846A/en unknown
- 2020-11-23 EC ECSENADI202075215A patent/ECSP20075215A/es unknown
- 2020-11-23 CO CONC2020/0014506A patent/CO2020014506A2/es unknown
- 2020-11-23 NI NI202000089A patent/NI202000089A/es unknown
- 2020-11-23 CL CL2020003033A patent/CL2020003033A1/es unknown
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2023
- 2023-03-08 US US18/180,225 patent/US20230322924A1/en active Pending
Also Published As
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CL2020003033A1 (es) | 2021-04-16 |
NI202000089A (es) | 2021-01-21 |
KR20210012007A (ko) | 2021-02-02 |
AU2019274656A1 (en) | 2020-11-26 |
CN112912397A (zh) | 2021-06-04 |
WO2019224717A2 (fr) | 2019-11-28 |
US11603405B2 (en) | 2023-03-14 |
WO2019224717A3 (fr) | 2020-03-05 |
MX2020012587A (es) | 2021-04-28 |
JOP20200302A1 (ar) | 2020-11-23 |
EP3802608A2 (fr) | 2021-04-14 |
WO2019224717A9 (fr) | 2021-02-04 |
SG11202011270QA (en) | 2020-12-30 |
PH12020551920A1 (en) | 2021-06-14 |
CA3101271A1 (fr) | 2019-11-28 |
PE20210132A1 (es) | 2021-01-19 |
CO2020014506A2 (es) | 2020-12-10 |
AR115422A1 (es) | 2021-01-20 |
US20200048349A1 (en) | 2020-02-13 |
IL278846A (en) | 2021-01-31 |
BR112020023508A2 (pt) | 2021-03-30 |
TW202012443A (zh) | 2020-04-01 |
ECSP20075215A (es) | 2020-12-31 |
US20230322924A1 (en) | 2023-10-12 |
EA202092847A1 (ru) | 2021-04-20 |
CR20200568A (es) | 2021-02-26 |
JP2021524249A (ja) | 2021-09-13 |
UY38245A (es) | 2019-11-29 |
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