CA3181026A1 - Methods for treating or preventing sars-cov-2 infections and covid-19 with anti-sars-cov-2 spike glycoprotein antibodies - Google Patents
Methods for treating or preventing sars-cov-2 infections and covid-19 with anti-sars-cov-2 spike glycoprotein antibodies Download PDFInfo
- Publication number
- CA3181026A1 CA3181026A1 CA3181026A CA3181026A CA3181026A1 CA 3181026 A1 CA3181026 A1 CA 3181026A1 CA 3181026 A CA3181026 A CA 3181026A CA 3181026 A CA3181026 A CA 3181026A CA 3181026 A1 CA3181026 A1 CA 3181026A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/102—Coronaviridae (F)
- C07K16/104—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (67)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063034348P | 2020-06-03 | 2020-06-03 | |
| US63/034,348 | 2020-06-03 | ||
| US202063036956P | 2020-06-09 | 2020-06-09 | |
| US63/036,956 | 2020-06-09 | ||
| US202063038274P | 2020-06-12 | 2020-06-12 | |
| US63/038,274 | 2020-06-12 | ||
| US202063043336P | 2020-06-24 | 2020-06-24 | |
| US63/043,336 | 2020-06-24 | ||
| US202063060592P | 2020-08-03 | 2020-08-03 | |
| US63/060,592 | 2020-08-03 | ||
| US202063062961P | 2020-08-07 | 2020-08-07 | |
| US63/062,961 | 2020-08-07 | ||
| US202063065799P | 2020-08-14 | 2020-08-14 | |
| US63/065,799 | 2020-08-14 | ||
| US202063084881P | 2020-09-29 | 2020-09-29 | |
| US202063085066P | 2020-09-29 | 2020-09-29 | |
| US63/084,881 | 2020-09-29 | ||
| US63/085,066 | 2020-09-29 | ||
| US202063089399P | 2020-10-08 | 2020-10-08 | |
| US63/089,399 | 2020-10-08 | ||
| US202063090690P | 2020-10-12 | 2020-10-12 | |
| US63/090,690 | 2020-10-12 | ||
| US202063094133P | 2020-10-20 | 2020-10-20 | |
| US63/094,133 | 2020-10-20 | ||
| US202063105779P | 2020-10-26 | 2020-10-26 | |
| US63/105,779 | 2020-10-26 | ||
| US202063106696P | 2020-10-28 | 2020-10-28 | |
| US63/106,696 | 2020-10-28 | ||
| US202063112140P | 2020-11-10 | 2020-11-10 | |
| US63/112,140 | 2020-11-10 | ||
| US202063116773P | 2020-11-20 | 2020-11-20 | |
| US63/116,773 | 2020-11-20 | ||
| US202063119593P | 2020-11-30 | 2020-11-30 | |
| US63/119,593 | 2020-11-30 | ||
| US202063120065P | 2020-12-01 | 2020-12-01 | |
| US63/120,065 | 2020-12-01 | ||
| US202063124980P | 2020-12-14 | 2020-12-14 | |
| US63/124,980 | 2020-12-14 | ||
| US202063131627P | 2020-12-29 | 2020-12-29 | |
| US63/131,627 | 2020-12-29 | ||
| US202163141423P | 2021-01-25 | 2021-01-25 | |
| US63/141,423 | 2021-01-25 | ||
| US202163141952P | 2021-01-26 | 2021-01-26 | |
| US63/141,952 | 2021-01-26 | ||
| US202163142471P | 2021-01-27 | 2021-01-27 | |
| US63/142,471 | 2021-01-27 | ||
| US202163144789P | 2021-02-02 | 2021-02-02 | |
| US63/144,789 | 2021-02-02 | ||
| US202163150978P | 2021-02-18 | 2021-02-18 | |
| US63/150,978 | 2021-02-18 | ||
| US202163162504P | 2021-03-17 | 2021-03-17 | |
| US63/162,504 | 2021-03-17 | ||
| US202163162996P | 2021-03-18 | 2021-03-18 | |
| US63/162,996 | 2021-03-18 | ||
| US202163164488P | 2021-03-22 | 2021-03-22 | |
| US63/164,488 | 2021-03-22 | ||
| US202163165654P | 2021-03-24 | 2021-03-24 | |
| US63/165,654 | 2021-03-24 | ||
| US202163166187P | 2021-03-25 | 2021-03-25 | |
| US63/166,187 | 2021-03-25 | ||
| US202163173468P | 2021-04-11 | 2021-04-11 | |
| US63/173,468 | 2021-04-11 | ||
| US202163185301P | 2021-05-06 | 2021-05-06 | |
| US63/185,301 | 2021-05-06 | ||
| US202163186029P | 2021-05-07 | 2021-05-07 | |
| US63/186,029 | 2021-05-07 | ||
| PCT/US2021/035556 WO2021247779A1 (en) | 2020-06-03 | 2021-06-02 | METHODS FOR TREATING OR PREVENTING SARS-CoV-2 INFECTIONS AND COVID-19 WITH ANTI-SARS-CoV-2 SPIKE GLYCOPROTEIN ANTIBODIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3181026A1 true CA3181026A1 (en) | 2021-12-09 |
Family
ID=78829987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3181026A Pending CA3181026A1 (en) | 2020-06-03 | 2021-06-02 | Methods for treating or preventing sars-cov-2 infections and covid-19 with anti-sars-cov-2 spike glycoprotein antibodies |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11999777B2 (https=) |
| EP (1) | EP4161960A1 (https=) |
| JP (1) | JP7851613B2 (https=) |
| KR (1) | KR20230019166A (https=) |
| CN (1) | CN116057069A (https=) |
| AU (1) | AU2021283349A1 (https=) |
| BR (1) | BR112022024662A2 (https=) |
| CA (1) | CA3181026A1 (https=) |
| CL (1) | CL2022003390A1 (https=) |
| CR (1) | CR20220660A (https=) |
| IL (1) | IL298425A (https=) |
| MX (1) | MX2022014852A (https=) |
| PH (1) | PH12022500028A1 (https=) |
| TW (1) | TW202210506A (https=) |
| WO (1) | WO2021247779A1 (https=) |
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| HRP20240182T1 (hr) | 2020-03-26 | 2024-04-26 | Vanderbilt University | Ljudska monoklonska protutijela za teški akutni respiratorni sindrom koronavirusa 2 (sars-cov-2) |
| KR20250107297A (ko) | 2020-04-02 | 2025-07-11 | 리제너론 파아마슈티컬스, 인크. | 항-sars-cov-2 스파이크 당단백질 항체 및 항원-결합 단편 |
| BR112022024662A2 (pt) | 2020-06-03 | 2023-04-04 | Regeneron Pharma | Métodos para tratamento ou prevenção de infecções por sars-cov-2 e covid-19 com anticorpos de glicoproteína spike anti-sars-cov-2 |
| US12496470B2 (en) | 2021-07-14 | 2025-12-16 | Regeneron Pharmaceuticals, Inc. | Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments |
| JP2024530672A (ja) | 2021-08-11 | 2024-08-23 | アールエヌエーイミューン、インコーポレイテッド | 新規なコロナウイルス感染症に対するｍＲＮＡワクチンの組成物および方法 |
| WO2023122211A2 (en) * | 2021-12-21 | 2023-06-29 | Duke University | Coronavirus antibodies and uses thereof |
| US12280104B2 (en) | 2022-11-01 | 2025-04-22 | RNAimmune, Inc. | Composition and methods for MRNA vaccines against novel omicron coronavirus infections |
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| JP7851613B2 (ja) | 2026-04-27 |
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