BR112015013784A2 - aplicação, manipulação e otimização de sistemas, métodos e composições para manipulação de sequência e aplicações terapêuticas - Google Patents

aplicação, manipulação e otimização de sistemas, métodos e composições para manipulação de sequência e aplicações terapêuticas

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Publication number
BR112015013784A2
BR112015013784A2 BR112015013784A BR112015013784A BR112015013784A2 BR 112015013784 A2 BR112015013784 A2 BR 112015013784A2 BR 112015013784 A BR112015013784 A BR 112015013784A BR 112015013784 A BR112015013784 A BR 112015013784A BR 112015013784 A2 BR112015013784 A2 BR 112015013784A2
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BR
Brazil
Prior art keywords
manipulation
application
methods
systems
optimization
Prior art date
Application number
BR112015013784A
Other languages
English (en)
Inventor
Zhang Feng
Ran Fei
Swiech Lukasz
HEIDENREICH Matthias
Original Assignee
Massachusetts Inst Technology
Harvard College
Broad Inst Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49883289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015013784(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Massachusetts Inst Technology, Harvard College, Broad Inst Inc filed Critical Massachusetts Inst Technology
Publication of BR112015013784A2 publication Critical patent/BR112015013784A2/pt

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • C12N2310/00—Structure or type of the nucleic acid
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Abstract

resumo patente de invenã§ã£o para "aplicaã‡ãƒo, manipulaã‡ãƒo e otimizaã‡ãƒo de sistemas, mã‰todos e composiã‡ã•es para manipulaã‡ãƒo de sequãšncia e aplicaã‡ã•es terapãšuticas" a invenã§ã£o prov㪠a aplicaã§ã£o, manipulaã§ã£o e otimizaã§ã£o de sistemas, mã©todos, e composiã§ãµes para manipulaã§ã£o de sequãªncias e/ou atividades de sequãªncias alvo. sã£o providos sistemas de aplicaã§ã£o e tecidos ou ã³rgã£os que sã£o visados como sã­tios de aplicaã§ã£o. sã£o tambã©m providos vetores e sistemas de vetores alguns dos quais codificam um ou mais componentes de um complexo crispr, bem como mã©todos para o desenho e uso desses vetores. tambã©m providos sã£o mã©todos de dirigir a formaã§ã£o do complexo crispr em cã©lulas eucariã³ticas para assegurar especificidade aumentada para reconhecimento do alvo e evitar a toxicidade e para editar ou modificar um local alvo em um local genã´mico de interesse para alterar ou melhorar o estado de uma doenã§a ou uma afecã§ã£o.
BR112015013784A 2012-12-12 2013-12-12 aplicação, manipulação e otimização de sistemas, métodos e composições para manipulação de sequência e aplicações terapêuticas BR112015013784A2 (pt)

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US201261736527P 2012-12-12 2012-12-12
US201361748427P 2013-01-02 2013-01-02
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US201361769046P 2013-02-25 2013-02-25
US201361802174P 2013-03-15 2013-03-15
US201361791409P 2013-03-15 2013-03-15
US201361806375P 2013-03-28 2013-03-28
US201361814263P 2013-04-20 2013-04-20
US201361819803P 2013-05-06 2013-05-06
US201361828130P 2013-05-28 2013-05-28
US201361835931P 2013-06-17 2013-06-17
US201361836123P 2013-06-17 2013-06-17
US201361847537P 2013-07-17 2013-07-17
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US20170107536A1 (en) 2017-04-20
RU2015128057A (ru) 2019-03-27
ZA201504132B (en) 2022-03-30
CN105164264B (zh) 2021-05-07
US20140242699A1 (en) 2014-08-28
KR20150105956A (ko) 2015-09-18
WO2014093622A2 (en) 2014-06-19
ES2658401T3 (es) 2018-03-09
DK3327127T3 (da) 2021-06-28
HK1220725A1 (zh) 2017-05-12
SG11201504523UA (en) 2015-07-30
JP7228059B2 (ja) 2023-02-22
US20140179770A1 (en) 2014-06-26
SG10201912328UA (en) 2020-02-27
EP3327127B1 (en) 2021-03-24
WO2014093622A8 (en) 2014-12-04
CN110872583A (zh) 2020-03-10
DK2931897T3 (en) 2018-02-05
AU2013359199A1 (en) 2015-07-30
IL293526A (en) 2022-08-01
HK1252619A1 (zh) 2019-05-31
MX2022001378A (es) 2022-06-23
HK1215048A1 (zh) 2016-08-12
IL239317B (en) 2022-07-01
AU2019283878A1 (en) 2020-01-23

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