AU2013323426A1 - Modulation of ire1 - Google Patents
Modulation of ire1 Download PDFInfo
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- AU2013323426A1 AU2013323426A1 AU2013323426A AU2013323426A AU2013323426A1 AU 2013323426 A1 AU2013323426 A1 AU 2013323426A1 AU 2013323426 A AU2013323426 A AU 2013323426A AU 2013323426 A AU2013323426 A AU 2013323426A AU 2013323426 A1 AU2013323426 A1 AU 2013323426A1
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- disease
- nhc
- compound
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| WO2015178770A1 (en) | 2014-05-19 | 2015-11-26 | Stichting Het Nederlands Kanker Instituut | Compositions for cancer treatment |
| WO2016004254A1 (en) * | 2014-07-01 | 2016-01-07 | The Regents Of The University Of California | Combined modulation of ire1 |
| US10053465B2 (en) | 2015-08-26 | 2018-08-21 | Incyte Corporation | Pyrrolopyrimidine derivatives as TAM inhibitors |
| WO2017152117A1 (en) * | 2016-03-03 | 2017-09-08 | Cornell University | Small molecule ire1-alpha inhibitors |
| TWI753892B (zh) | 2016-03-28 | 2022-02-01 | 美商英塞特公司 | 作為ｔａｍ抑制劑之吡咯并三嗪化合物 |
| US10934275B2 (en) | 2016-12-02 | 2021-03-02 | Cornell University | IRE1 small molecule inhibitors |
| US10392367B2 (en) | 2017-06-01 | 2019-08-27 | Quentis Therapeutics, Inc. | IRE1 small molecule inhibitors |
| AU2018278311B2 (en) | 2017-06-01 | 2021-10-07 | Cornell University | IRE1 small molecule inhibitors |
| CN107446952B (zh) * | 2017-07-31 | 2020-04-28 | 苏州大学附属儿童医院 | 一种用于肠外营养相关性肝病药物的制备方法 |
| KR20200066301A (ko) * | 2017-09-01 | 2020-06-09 | 옵티키라 엘엘씨 | Ire1 억제를 위한 화합물 및 조성물 |
| MA50655B1 (fr) | 2017-09-27 | 2021-11-30 | Incyte Corp | Sels de dérivés de pyrrolotriazine utiles en tant qu'inhibiteurs de tam |
| JP7271538B2 (ja) * | 2017-11-10 | 2023-05-11 | コーネル・ユニバーシティー | 低分子ｉｒｅ１阻害剤 |
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| EP3891130B1 (en) * | 2018-12-03 | 2023-10-25 | Cornell University | Ire1 small molecule inhibitors |
| JP7539892B2 (ja) | 2019-01-03 | 2024-08-26 | ジェネンテック， インコーポレイテッド | 癌疾患の処置のためのエンドリボヌクレアーゼのイノシトール要求酵素ｉ（ｉｒｅｉアルファ）の阻害剤としてのピリド－ピリミジノン化合物及びプテリジノン化合物 |
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| CN112409361B (zh) * | 2019-08-23 | 2022-08-16 | 山东轩竹医药科技有限公司 | Tam抑制剂及其用途 |
| WO2021041970A1 (en) * | 2019-08-29 | 2021-03-04 | Hibercell, Inc. | Perk inhibiting imidazolopyrazine compounds |
| CN115697343A (zh) | 2020-03-06 | 2023-02-03 | 因赛特公司 | 包含axl/mer和pd-1/pd-l1抑制剂的组合疗法 |
| CN116583276A (zh) * | 2020-11-13 | 2023-08-11 | 加利福尼亚大学董事会 | IRE1α抑制剂及其用途 |
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2013
- 2013-09-26 AU AU2013323426A patent/AU2013323426A1/en not_active Abandoned
- 2013-09-26 RU RU2015115631A patent/RU2015115631A/ru not_active Application Discontinuation
- 2013-09-26 WO PCT/US2013/062039 patent/WO2014052669A1/en not_active Ceased
- 2013-09-26 CN CN201380061276.4A patent/CN104995192A/zh active Pending
- 2013-09-26 CA CA2886240A patent/CA2886240A1/en active Pending
- 2013-09-26 MX MX2015003874A patent/MX2015003874A/es unknown
- 2013-09-26 BR BR112015006828A patent/BR112015006828A8/pt not_active Application Discontinuation
- 2013-09-26 SG SG11201502331RA patent/SG11201502331RA/en unknown
- 2013-09-26 KR KR1020157010751A patent/KR20150061651A/ko not_active Withdrawn
- 2013-09-26 JP JP2015534672A patent/JP2015532287A/ja active Pending
- 2013-09-26 EP EP13841491.7A patent/EP2900673A4/en not_active Withdrawn
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2015
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2018
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|---|---|
| EP2900673A4 (en) | 2016-10-19 |
| US10131668B2 (en) | 2018-11-20 |
| US11613544B2 (en) | 2023-03-28 |
| KR20150061651A (ko) | 2015-06-04 |
| BR112015006828A2 (pt) | 2017-07-04 |
| US10822340B2 (en) | 2020-11-03 |
| US20190084989A1 (en) | 2019-03-21 |
| JP2015532287A (ja) | 2015-11-09 |
| MX2015003874A (es) | 2015-12-16 |
| IL237970A0 (en) | 2015-05-31 |
| EP2900673A1 (en) | 2015-08-05 |
| BR112015006828A8 (pt) | 2019-09-17 |
| RU2015115631A (ru) | 2016-11-20 |
| WO2014052669A1 (en) | 2014-04-03 |
| US20210155626A1 (en) | 2021-05-27 |
| CA2886240A1 (en) | 2014-04-03 |
| CN104995192A (zh) | 2015-10-21 |
| US20160024094A1 (en) | 2016-01-28 |
| SG11201502331RA (en) | 2015-04-29 |
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