ATE10548T1 - Verfahren der konzentrierten zone in heterogenen immunoassays. - Google Patents

Verfahren der konzentrierten zone in heterogenen immunoassays.

Info

Publication number
ATE10548T1
ATE10548T1 AT81302826T AT81302826T ATE10548T1 AT E10548 T1 ATE10548 T1 AT E10548T1 AT 81302826 T AT81302826 T AT 81302826T AT 81302826 T AT81302826 T AT 81302826T AT E10548 T1 ATE10548 T1 AT E10548T1
Authority
AT
Austria
Prior art keywords
zone
signal
immunosorbing
procedure
mip
Prior art date
Application number
AT81302826T
Other languages
German (de)
English (en)
Inventor
Henry Kork Tom
Gerald Leroy Rowley
Original Assignee
Syva Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Company filed Critical Syva Company
Application granted granted Critical
Publication of ATE10548T1 publication Critical patent/ATE10548T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/805Test papers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT81302826T 1980-08-07 1981-06-23 Verfahren der konzentrierten zone in heterogenen immunoassays. ATE10548T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/176,177 US4366241A (en) 1980-08-07 1980-08-07 Concentrating zone method in heterogeneous immunoassays
EP81302826A EP0046004B1 (en) 1980-08-07 1981-06-23 Concentrating zone method in heterogeneous immunoassays

Publications (1)

Publication Number Publication Date
ATE10548T1 true ATE10548T1 (de) 1984-12-15

Family

ID=22643311

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81302826T ATE10548T1 (de) 1980-08-07 1981-06-23 Verfahren der konzentrierten zone in heterogenen immunoassays.

Country Status (9)

Country Link
US (1) US4366241A (en:Method)
EP (1) EP0046004B1 (en:Method)
JP (3) JPS5763454A (en:Method)
AT (1) ATE10548T1 (en:Method)
CA (1) CA1174595A (en:Method)
DE (1) DE3167436D1 (en:Method)
HK (1) HK15887A (en:Method)
MY (1) MY8700300A (en:Method)
SG (1) SG89186G (en:Method)

Families Citing this family (1257)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US4540659A (en) * 1981-04-17 1985-09-10 Syva Company Simultaneous calibration heterogeneous immunoassay
US4533629A (en) * 1981-04-17 1985-08-06 Syva Company Simultaneous calibration heterogeneous immunoassay
US5156953A (en) * 1979-12-26 1992-10-20 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4843000A (en) * 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US5432057A (en) * 1979-12-26 1995-07-11 Syva Company Simultaneous calibration heterogeneous immunoassay
US4849338A (en) * 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
JPS5782766A (en) * 1980-11-11 1982-05-24 Konishiroku Photo Ind Co Ltd Amynological measuring element
US4752562A (en) * 1981-01-23 1988-06-21 Baxter Travenol Laboratories, Inc. Detection of serum antibody and surface antigen by radial partition immunoassay
US4774174A (en) * 1981-01-23 1988-09-27 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4786606A (en) * 1981-01-23 1988-11-22 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US4447526A (en) * 1981-04-20 1984-05-08 Miles Laboratories, Inc. Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
US5624814A (en) * 1981-08-20 1997-04-29 Becton Dickinson And Company Culture medium and method for culturing body fluids containing antibiotics
CA1209889A (en) * 1981-09-18 1986-08-19 Litai Weng Homogeneous assay on a non-porous surface
US4463090A (en) * 1981-09-30 1984-07-31 Harris Curtis C Cascade amplification enzyme immunoassay
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4654300A (en) * 1982-04-02 1987-03-31 Syntex (U.S.A.) Inc. Fluorescent microbead quenching assay
IL68506A (en) * 1982-05-04 1988-06-30 Syva Co Simultaneous calibration heterogeneous immunoassay method and device and kit for use therein
CA1228811A (en) 1983-05-05 1987-11-03 Robert G. Pergolizzi Assay method utilizing polynucleotide sequences
US4552839A (en) * 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
US4522786A (en) * 1983-08-10 1985-06-11 E. I. Du Pont De Nemours And Company Multilayered test device for detecting analytes in liquid test samples
EP0149168B1 (en) * 1983-12-19 1991-04-24 Daiichi Pure Chemicals Co. Ltd. Immunoassay
SE446229B (sv) * 1984-01-25 1986-08-18 Syn Tek Ab Sett och anordning for detektering av en analyt i ett prov som bringas att passera en yta till vilken bundits ett emne med specifik affinitet till analyten
US4791056A (en) * 1984-03-27 1988-12-13 Syntex (U.S.A.) Inc. Calibration device for heterogeneous immunoassay
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4624929A (en) * 1984-12-03 1986-11-25 Syntex (U.S.A.) Inc. Sample collector and assay device and method for its use
SE458643B (sv) * 1984-12-07 1989-04-17 Pharmacia Ab Anordning med kolonnelement uppdelat i provparti och referenspatri
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
EP0207152B1 (en) * 1984-12-20 1992-12-30 Nycomed Pharma As Solid phase diffusion assay
US5958790A (en) * 1984-12-20 1999-09-28 Nycomed Imaging As Solid phase transverse diffusion assay
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
WO1986005592A1 (en) * 1985-03-18 1986-09-25 National Research Development Corporation Antigenically active protein and its use in the diagnosis of gonorrhoea
US5879881A (en) * 1985-04-04 1999-03-09 Hybritech, Incorporated Solid phase system for use in ligand-receptor assays
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
US4623461A (en) * 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US4670381A (en) * 1985-07-19 1987-06-02 Eastman Kodak Company Heterogeneous immunoassay utilizing horizontal separation in an analytical element
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4900663A (en) * 1985-09-13 1990-02-13 Environmental Diagnostics, Inc. Test kit for determining the presence of organic materials and method of utilizing same
US5240844A (en) * 1985-09-13 1993-08-31 Wie Siong I Test kit for determining the presence of organic materials and method of utilizing same
US4675300A (en) * 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
TW203120B (en:Method) * 1985-10-04 1993-04-01 Abbott Lab
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
DE3543749A1 (de) * 1985-12-11 1987-06-19 Boehringer Mannheim Gmbh Verfahren zur herstellung eines reagenzpapieres fuer die immunologische analyse
EP0250557A4 (en) * 1985-12-12 1990-01-11 Dennison Mfg Co DETERMINATION OF TEST SUBSTANCES.
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US5273877A (en) * 1985-12-24 1993-12-28 Massachusetts Institute Of Technology Non-histological cell type determination
US5160701A (en) * 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
JPS62231168A (ja) * 1986-03-21 1987-10-09 ハイブリテツク・インコ−ポレイテツド アナライト−レセプタ−分析用内部標準を設けるための改良法
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4851210A (en) * 1986-05-22 1989-07-25 Genelabs Incorporated Blood typing device
WO1987007384A1 (en) * 1986-05-30 1987-12-03 Quidel Enzyme immunoassay device
AU602694B2 (en) * 1986-06-09 1990-10-25 Ortho Diagnostic Systems Inc. Improved colloidal gold membrane assay
AU598820B2 (en) * 1986-06-20 1990-07-05 Molecular Devices Corporation Zero volume electrochemical cell
US4915812A (en) * 1986-06-20 1990-04-10 Molecular Devices Corporation Zero volume cell
US5120504A (en) * 1986-07-14 1992-06-09 Hybritech Incorporated Apparatus for immunoassays with vent chennels in the container side wall
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4790979A (en) * 1986-08-29 1988-12-13 Technimed Corporation Test strip and fixture
US5260193A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US4959307A (en) * 1986-09-05 1990-09-25 Syntex (U.S.A.) Inc. Immunoseparating strip
US5085988A (en) * 1986-09-05 1992-02-04 Syntex (U.S.A.) Inc. Immunoseparating strip
US5260194A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US4963468A (en) * 1986-09-05 1990-10-16 Syntex (U.S.A.) Inc. Immunoseparating strip
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
ATE92525T1 (de) * 1986-10-23 1993-08-15 Behringwerke Ag Bioaffine poroese festphasen, ein verfahren zur herstellung von bioaffinen poroesen festphasen und ihre verwendung.
DE3636060C3 (de) * 1986-10-23 1994-04-07 Behringwerke Ag Bioaffine poröse Festphase, Verfahren zu deren Herstellung und ihre Verwendung
US5030558A (en) * 1986-11-07 1991-07-09 Syntex (U.S.A.) Inc. Qualitative immunochromatographic method and device
EP0271204A3 (en) * 1986-11-07 1989-10-25 Syntex (U.S.A.) Inc. Immunochromatographic method and device
JPH01501819A (ja) * 1986-11-13 1989-06-22 ジェネ ラブス,インコーポレイティド 血液親和性診断方法
US4978502A (en) * 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US4769333A (en) * 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4859603A (en) * 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US5079142A (en) * 1987-01-23 1992-01-07 Synbiotics Corporation Orthogonal flow immunoassays and devices
US4920046A (en) * 1987-02-20 1990-04-24 Becton, Dickinson And Company Process, test device, and test kit for a rapid assay having a visible readout
US4833087A (en) * 1987-02-27 1989-05-23 Eastman Kodak Company Disposable container configured to produce uniform signal
US5250412A (en) * 1987-03-23 1993-10-05 Diamedix Corporation Swab device and method for collecting and analyzing a sample
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
ATE195022T1 (de) 1987-04-27 2000-08-15 Unilever Nv Spezifische bindungstestverfahren
US4973549A (en) * 1987-06-22 1990-11-27 Chemtrak Corporation Quantitative diagnostic assay employing signal producing agent bound to support and measuring migration distance of detectable signal
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US5055258A (en) * 1987-08-19 1991-10-08 Flemming Gmbh Device for ascertaining the presence of an antigen or of an antibody in a liquid sample
US4981786A (en) * 1987-09-04 1991-01-01 Syntex (U.S.A.) Inc. Multiple port assay device
DE3730059A1 (de) * 1987-09-08 1989-03-30 Behringwerke Ag Verfahren zur bestimmung von "loeslichem" fibrin
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
DE3879048T2 (de) * 1987-09-11 1993-09-02 Abbott Lab Geraet fuer die laterale immunochromatographische bestimmung.
US5006464A (en) * 1987-10-01 1991-04-09 E-Y Laboratories, Inc. Directed flow diagnostic device and method
FR2621393B1 (fr) * 1987-10-05 1991-12-13 Toledano Jacques Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
US4999163A (en) * 1987-10-29 1991-03-12 Hygeia Sciences, Inc. Disposable, pre-packaged device for conducting immunoassay procedures
US4943525A (en) * 1987-11-02 1990-07-24 Bioventures, Inc. Simultaneous immunoassay for the determination of antigens and antibodies
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US4818677A (en) * 1987-12-03 1989-04-04 Monoclonal Antibodies, Inc. Membrane assay using focused sample application
JPH0630628B2 (ja) * 1987-12-16 1994-04-27 キング醸造株式会社 生細胞数及び活力の測定方法
US5206177A (en) * 1988-01-21 1993-04-27 Boehringer Mannheim Corporation Apparatus for determining an analyte and method therefor
US4963325A (en) * 1988-05-06 1990-10-16 Hygeia Sciences, Inc. Swab expressor immunoassay device
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5164294A (en) * 1988-05-17 1992-11-17 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5573919A (en) * 1988-06-02 1996-11-12 Carter-Wallace Assay using an absorbent material
US5620845A (en) * 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5059522A (en) * 1988-08-18 1991-10-22 Wayne Lawrence G Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
EP0442872A4 (en) * 1988-11-14 1992-08-05 Idexx Corp. Dual absorbent analyte detection
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5252293A (en) * 1989-01-17 1993-10-12 Vladimir Drbal Analytical slide with porous filter membrane
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
EP0386644B1 (en) * 1989-03-10 1997-06-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Reagents for the determination of drugs
US5106761A (en) * 1989-03-13 1992-04-21 International Canine Genetics, Inc. Method for detecting molecules in a liquid medium
US5340539A (en) * 1989-03-16 1994-08-23 Chemtrak, Inc. Non-instrumented cholesterol assay
ATE179522T1 (de) * 1989-07-17 1999-05-15 Univ Rockefeller Verfahren und mittel zum nachweis von krankheitszuständen aus änderungen im östrogenstoffwechsel
US5155049A (en) * 1989-08-22 1992-10-13 Terrapin Technologies, Inc. Blotting technique for membrane assay
US5185127A (en) * 1989-09-21 1993-02-09 Becton, Dickinson And Company Test device including flow control means
US5075078A (en) * 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
US5147780A (en) * 1989-12-01 1992-09-15 Sangstat Medical Corporation Multiwell stat test
US5646046A (en) * 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5922615A (en) * 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
JP3070764B2 (ja) * 1990-03-12 2000-07-31 バイオサイト・ダイアグノスティックス・インコーポレイテッド 生物学的検定装置及びそれを用いた検定方法
US5559032A (en) * 1990-06-29 1996-09-24 Pomeroy; Patrick C. Method and apparatus for post-transfer assaying of material on solid support
US5158869A (en) * 1990-07-06 1992-10-27 Sangstat Medical Corporation Analyte determination using comparison of juxtaposed competitive and non-competitive elisa results and device therefore
US5143852A (en) 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
JPH05504841A (ja) * 1990-09-14 1993-07-22 バイオサイト・ダイアグノスティックス・インコーポレイテッド リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途
JP2628792B2 (ja) * 1990-09-26 1997-07-09 アカーズ・リサーチ・コーポレーシヨン 改良されたリガンドのアッセイ
US5231035A (en) * 1991-01-11 1993-07-27 Akers Research Corporation Latex agglutination assay
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5264589A (en) * 1991-06-06 1993-11-23 Miles Inc. Merocyanine protein error indicators
DE4121493A1 (de) * 1991-06-28 1993-01-07 Draegerwerk Ag Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
US5451504A (en) * 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
ES2154265T3 (es) * 1991-10-18 2001-04-01 Synsorb Biotech Inc Tratamiento de la disenteria bacteriana.
AU3439693A (en) * 1992-01-22 1993-09-01 Abbott Laboratories Calibration reagents for semi-quantitative binding assays and devices
EP0630475B1 (en) * 1992-03-10 2000-09-06 Quidel Corporation Red blood cell separation means for specific binding assays
DE4216696C2 (de) * 1992-04-10 1995-01-26 Deutsche Aerospace Verfahren und Vorrichtung zur Empfindlichkeits- und Selektivitätssteigerung bei Immuno-Assays, Molekül-Rezeptor-, DNA-komplementär-DNA- und Gast-Wirtsmolekül-Wechselwirkungs-Assays
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
EP0583980A1 (en) * 1992-08-20 1994-02-23 Eli Lilly And Company Method for generating monoclonal antibodies from rabbits
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
AU670108B2 (en) 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US5344754A (en) * 1993-01-13 1994-09-06 Avocet Medical, Inc. Assay timed by electrical resistance change and test strip
US5500375A (en) * 1993-04-13 1996-03-19 Serex, Inc. Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
US5695928A (en) * 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
USD361842S (en) 1994-05-23 1995-08-29 Carter Wallace, Inc. Immunoassay test cartridge
US5550032A (en) * 1994-05-27 1996-08-27 George Mason University Biological assay for microbial contamination
MX9701075A (es) 1994-08-12 1998-03-31 Myriad Genetics Inc Mutaciones en vivo y polimorfismos en el gen de susceptibilidad al cancer de pecho y ovario enlazado con 17q.
WO1996005307A2 (en) 1994-08-12 1996-02-22 Myriad Genetics, Inc. 17q-LINKED BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP3010699U (ja) * 1994-10-29 1995-05-02 株式会社ニッポンジーン 直接採尿の可能なクロマト式検査装置
US5633149A (en) 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
USD369868S (en) 1995-01-31 1996-05-14 Carter-Wallace, Inc. Immunoassay test cartridge
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5712172A (en) 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US6319676B1 (en) * 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
EP0873363B1 (en) 1995-06-14 2010-10-06 The Regents of The University of California High affinity human antibodies to tumor antigens
AU6720096A (en) 1995-08-09 1997-03-05 Quidel Corporation Test strip and method for one step lateral flow assay
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
NZ326525A (en) 1995-12-18 1999-11-29 Endorecherche Inc Chromosome 13-linked breast cancer susceptibility gene
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
EP0880598A4 (en) * 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
US6924094B1 (en) 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP1728875A3 (en) 1996-02-08 2007-05-09 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
JP2000504575A (ja) 1996-02-08 2000-04-18 アフィメトリックス,インコーポレイテッド 微生物のチップベースの種分化および表現型特徴付け
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
CA2249994A1 (en) * 1996-03-22 1997-09-25 University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
CN1201005C (zh) * 1996-05-22 2005-05-11 维文蒂阿生物技术股份有限公司 特异性检测癌细胞的抗原结合片段、编码所述片段的dna、以及它们在预防和检测癌症上的用途
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
EP1947183B1 (en) 1996-08-16 2013-07-17 Merck Sharp & Dohme Corp. Mammalian cell surface antigens; related reagents
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6433155B1 (en) 1996-09-24 2002-08-13 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US5998221A (en) * 1996-09-25 1999-12-07 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
US7585622B1 (en) * 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6475789B1 (en) * 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
AU4803697A (en) 1996-10-01 1998-04-24 Geron Corporation Telomerase reverse transcriptase
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US5710005A (en) * 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
AU5697098A (en) 1996-12-13 1998-07-03 Schering Corporation Mammalian cell surface antigens; related reagents
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
DK0966533T3 (da) 1997-02-07 2010-01-04 Us Gov Health & Human Serv Aktivitetsafhængig neurotrof faktor III (ADNF III).
AU6439198A (en) 1997-03-05 1998-09-22 Point Of Care Technologies, Inc. Fluid specimen collecting and testing apparatus
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
ES2340210T3 (es) 1997-05-07 2010-05-31 Schering Corporation Proteinas humanas receptoras de tipo toll, reactivos asociados y metodos.
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
WO1999002562A1 (en) 1997-07-09 1999-01-21 Schering Corporation Isolated dendritic cell membrane protein genes
US6228638B1 (en) 1997-07-11 2001-05-08 University Of North Texas, Health Science Center At Fort Worth Escherichia coli CSRB gene and RNA encoded thereby
US20030157642A1 (en) 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6521421B1 (en) * 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
ZA986596B (en) 1997-07-25 1999-02-08 Schering Corp Mammalian cytokine related reagents
PT1003861E (pt) 1997-08-01 2007-01-31 Schering Corp Proteínas de membrana de células de mamíferos;reagentes relacionados
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
US7252950B1 (en) * 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6960457B1 (en) 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US6521440B1 (en) * 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
US6599731B1 (en) 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
US6465186B1 (en) 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) * 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US6764830B1 (en) 1998-01-23 2004-07-20 The Regents Of The University Of California Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
EP1060253A2 (en) 1998-03-04 2000-12-20 Genencor International, Inc. Modified forms of pullulanase
US6284194B1 (en) 1998-03-11 2001-09-04 Albert E. Chu Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
NZ507033A (en) 1998-03-20 2004-06-25 Univ Missouri Compositions and methods for early pregnancy diagnosis
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
DE69931632T2 (de) 1998-03-30 2006-12-07 Orasure Technologies, Inc. Sammelapparat für einschrittigen test von mundflüssigkeiten
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
CA2735260A1 (en) * 1998-03-31 1999-10-07 Esoterix Genetic Laboratories, Llc Methods for the diagnosis and treatment of lung cancer by detection of proto-oncogene overexpression
US6274314B1 (en) 1998-04-02 2001-08-14 Nyxis Neurotherapies, Inc. Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
WO1999053295A1 (en) 1998-04-14 1999-10-21 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6348573B1 (en) 1998-04-27 2002-02-19 The Regents Of The University Of Michigan Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators
US6271044B1 (en) 1998-05-06 2001-08-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method and kit for detecting an analyte
EP1097378A2 (en) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Optical disc-based assay devices and methods
EP1098988B9 (en) 1998-07-21 2007-10-24 Danisco A/S Foodstuff
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
EP1806362B1 (en) 1998-07-28 2010-07-21 The Regents of the University of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
JP2002526079A (ja) 1998-09-21 2002-08-20 シェーリング コーポレイション ヒトインターロイキン−b50、治療的使用
EP0997476A3 (en) 1998-09-25 2000-07-19 Schering-Plough Antibodies to a mammalian Langerhans cell antigen and their uses
US7071324B2 (en) * 1998-10-13 2006-07-04 Brown University Research Foundation Systems and methods for sequencing by hybridization
JP3622532B2 (ja) * 1998-10-13 2005-02-23 松下電器産業株式会社 酵素免疫分析用試薬及びそれを用いた分析方法
AU1447600A (en) 1998-10-22 2000-05-08 Thomas J. Gardella Bioactive peptides and peptide derivatives of parathyroid hormone (pth) and parathyroid hormone-related peptide (pthrp)
US7297554B2 (en) * 1998-11-18 2007-11-20 Microdiagnostics, Inc. Immunoassay system
US6638760B1 (en) 1998-11-25 2003-10-28 Pe Corporation (Ny) Method and apparatus for flow-through hybridization
ATE531801T1 (de) 1999-01-11 2011-11-15 Schering Corp Interleukin-17-verwandte säugetier-cytokine, polynukleotide, die diese kodieren und deren verwndung
US6566051B1 (en) * 1999-01-15 2003-05-20 Medtox Scientific, Inc. Lateral flow test strip
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
AU3873200A (en) 1999-03-11 2000-09-28 Schering Corporation Mammalian cytokines; related reagents and methods
AU4057300A (en) 1999-03-30 2000-10-16 Board Of Regents, The University Of Texas System Compositions and methods for modifying toxic effects of proteinacious compounds
EP2336321A1 (en) 1999-05-13 2011-06-22 Medical Research Council Ox2 receptor homolog
AU5011400A (en) 1999-05-14 2000-12-05 Arbor Vita Corporation Molecular interactions in t cells
EP1950299A1 (en) 1999-06-01 2008-07-30 Schering Corporation Mammalian receptor proteins; related reagents and methods
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
SI1200592T1 (sl) 1999-07-30 2010-01-29 Schering Corp Sesalski citokini; sorodni reagenti
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
AU7734800A (en) * 1999-09-29 2001-04-30 General Hospital Corporation, The Polypeptide derivatives of parathyroid hormone (pth)
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
DK1226166T3 (da) 1999-10-18 2010-05-25 Prince Henrys Inst Med Res Immun-interaktive fragmenter af alpha C-underenheden af inhibin
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
EP2275447A1 (en) 1999-11-24 2011-01-19 Schering Corporation Methods of inhibiting metastasis
DK1247095T3 (da) 1999-12-06 2008-12-08 Univ Illinois TCR-proteiner med höj affinitet samt fremgangsmåder
FR2802214B1 (fr) * 1999-12-09 2005-07-22 Biomerieux Sa Nouveaux substrats chromogenes a base d'alizarine, leurs utilisations et compositions contenant de tels substrats
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
JP2003523208A (ja) 2000-01-25 2003-08-05 ザ ユニバーシティ オブ クイーンズランド 髄膜炎菌表面抗原NhhAの保存領域を含むタンパク質
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US20010051348A1 (en) * 2000-01-28 2001-12-13 Lee Chee Wee Novel ligands and methods for preparing same
WO2001059450A2 (en) 2000-02-08 2001-08-16 Sangamo Biosciences, Inc. Cells expressing zinc finger protein for drug discovery
US6792791B2 (en) * 2000-02-18 2004-09-21 Matsushita Electric Industrial Co., Ltd. Inspection chip for sensor measuring instrument
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
AU783559B2 (en) * 2000-03-09 2005-11-10 Colorado State University Research Foundation Use of recombinant antigens to determine the immune status of an animal
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
ATE416782T1 (de) 2000-04-18 2008-12-15 Schering Corp Medizinische verwendung von il-174 agonisten und antagonisten
JP4764590B2 (ja) 2000-04-29 2011-09-07 ユニバーシティー オブ アイオワ リサーチ ファウンデーション 黄班変性関連疾患の診断および治療
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
CN101654479A (zh) 2000-05-10 2010-02-24 先灵公司 哺乳动物细胞因子受体亚单位蛋白、相关试剂及方法
AUPQ755300A0 (en) 2000-05-17 2000-06-08 Monash University Immune potentiating compositions
MXPA02011618A (es) 2000-05-25 2003-03-10 Schering Corp Proteinas de receptor de humano, reactivos y metodos relacionados.
WO2005000087A2 (en) * 2003-06-03 2005-01-06 Chiron Corporation Gene products differentially expressed in cancerous colon cells and their methods of use ii
US6528321B1 (en) 2000-06-26 2003-03-04 Beckman Coulter, Inc. Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US6673614B2 (en) 2000-06-27 2004-01-06 Cell Genesys, Inc. Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
US6372516B1 (en) 2000-09-07 2002-04-16 Sun Biomedical Laboratories, Inc. Lateral flow test device
CN1452633A (zh) 2000-09-08 2003-10-29 先灵公司 哺乳动物基因、相关试剂及方法
EP1322755B1 (en) 2000-09-08 2010-08-18 Board of Regents, The University of Texas System Human and mouse targeting peptides identified by phage display
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
EP1356060B1 (en) * 2000-09-18 2005-12-14 Genencor International, Inc. Twin-arginine translocation in bacillus
AU2001294654A1 (en) * 2000-09-25 2002-04-08 The Regents Of The University Of California Model for neurodegenerative diseases involving amyloid accumulation
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
USD468437S1 (en) 2000-11-21 2003-01-07 Acon Laboratories, Inc. Test platform
WO2002044366A2 (en) * 2000-11-29 2002-06-06 Lynkeus Biotech Gmbh Retina-specific human proteins c70rf9, c120rf7, mpp4 and f379
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
US7087389B2 (en) 2001-02-09 2006-08-08 Council Of Scientific & Industrial Research Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
US20020168663A1 (en) * 2001-02-27 2002-11-14 Phan Brigitte Chau Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
CA2440615A1 (en) * 2001-03-12 2002-09-19 Affymetrix, Inc. Nucleic acid labeling compounds
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030228639A1 (en) * 2001-03-19 2003-12-11 Wright George L Prostate cancer markers
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
AU2002254524A1 (en) * 2001-04-06 2002-10-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health A Use of semenogelin in the diagnosis, prognosis and treatment of cancer
WO2002084291A1 (en) * 2001-04-12 2002-10-24 Arkray, Inc. Specimen analyzing implement
US6916626B1 (en) * 2001-04-25 2005-07-12 Rockeby Biomed Ltd. Detection of Candida
MXPA03010511A (es) 2001-05-18 2004-03-02 Danisco Metodo para preparar una masa con una enzima.
JP4454230B2 (ja) 2001-05-22 2010-04-21 メルク エンド カムパニー インコーポレーテッド β−セクレターゼ基質及びその使用
AU2002312410A1 (en) * 2001-06-08 2002-12-23 Target Protein Technologies, Inc. Tissue-specific endothelial membrane proteins
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
EP2003451B1 (en) 2001-06-26 2012-05-30 Senomyx, Inc. T1r1-t1r3 hetero-oligomeric umami taste receptors and cell lines that express said receptors and use thereof for identification of umami taste compounds
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
EP1439854B1 (en) * 2001-07-23 2016-12-14 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
JP4265149B2 (ja) * 2001-07-25 2009-05-20 セイコーエプソン株式会社 電気光学装置、電気光学装置の製造方法
ATE481497T1 (de) * 2001-08-01 2010-10-15 Univ Utah Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US6855561B2 (en) * 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
WO2003024993A2 (en) 2001-09-20 2003-03-27 Board Of Regents, The University Of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
US7108975B2 (en) * 2001-09-21 2006-09-19 Regents Of The University Of Michigan Atlastin
US7582425B2 (en) * 2001-09-21 2009-09-01 The Regents Of The University Of Michigan Atlastin
EP1961293A3 (en) 2001-09-27 2009-01-28 Pioneer Hi-Bred International, Inc. Phytate polynucleotides and methods of use
AU2002330102A1 (en) * 2001-09-28 2003-04-14 Aspenbio, Inc. Bovine pregnancy test
CA2462883A1 (en) 2001-10-12 2003-04-17 Schering Corporation Use of bispecific antibodies to regulate immune responses
US7537731B2 (en) * 2001-10-19 2009-05-26 Panasonic Corporation Specific binding analysis device
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
AU2002366097B2 (en) 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US20030099621A1 (en) 2001-11-29 2003-05-29 Robert Chow Stem cell screening and transplantation therapy for HIV infection
WO2003049599A2 (en) * 2001-12-07 2003-06-19 University Of Wyoming Methods and compositions for the diagnosis of asthma
US7875435B2 (en) * 2001-12-12 2011-01-25 Proteome Systems Ltd Diagnostic testing process
US7244393B2 (en) 2001-12-21 2007-07-17 Kimberly-Clark Worldwide, Inc. Diagnostic device and system
US8367013B2 (en) * 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US20050003459A1 (en) * 2002-01-30 2005-01-06 Krutzik Siegfried Richard Multi-purpose optical analysis disc for conducting assays and related methods for attaching capture agents
US7255986B2 (en) * 2002-01-31 2007-08-14 The Board Of Trustees Operating Michigan State University Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
WO2003065985A2 (en) 2002-02-01 2003-08-14 Schering Corporation Uses of mammalian cytokine; related reagents
US7094579B2 (en) 2002-02-13 2006-08-22 Xoma Technology Ltd. Eukaryotic signal sequences for prokaryotic expression
CA2477035A1 (en) * 2002-02-21 2003-09-04 Eastern Virginia Medical School Protein biomarkers that distinguish prostate cancer from non-malignant cells
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
EP1573035B1 (en) 2002-02-22 2015-09-02 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Brother of the regulator of imprinted sites (boris)
US6703216B2 (en) 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
JP2004003976A (ja) * 2002-04-05 2004-01-08 Matsushita Electric Ind Co Ltd 特異結合分析方法およびこれに用いるデバイス
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2391438A1 (en) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Psp94 diagnostic reagents and assays
CA2483958A1 (en) * 2002-05-02 2003-11-13 Aspenbio, Inc. Pregnancy detection
AU2003228809A1 (en) * 2002-05-03 2003-11-17 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
EP1532453B1 (en) * 2002-05-31 2013-08-21 Genetic Technologies Limited Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
WO2004003179A1 (en) 2002-06-27 2004-01-08 The University Of Queensland Differentiation modulating agents and uses therefor
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
DK2283868T3 (en) 2002-07-15 2016-04-25 Univ Texas PEPTIDES BINDING TO PHOSPHATIDYLETHANOLAMINE AND ITS USE IN TREATING VIRUS INFECTIONS AND CANCER
ATE497774T1 (de) 2002-07-15 2011-02-15 Univ Texas Screening kombinatorischer proteinbibliotheken mittels periplasmatischer expression
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
BR0312985A (pt) 2002-07-26 2005-06-21 Inst Medical W & E Hall Métodos para extrair ou induzir, em um mamìfero, uma resposta imune dirigida a um parasita, para tratar de modo terapêutico ou profilático um mamìfero para infecção por parasitas, para o tratamento e/ou a profilaxia de uma condição doentia de mamìfero, uso de uma composição,composição, composição de vacina, composição farmacêutica, anticorpo para inibir, parar ou retardar o inìcio ou progressão de uma condição doentia de mamìfero, uso de um anticorpo, métodos para detectar, em uma amostra bológica, uma molécula imunointerativa dirigida a um microorganismo e para detectar, monitorar ou de outra forma avaliar uma resposta imune dirigida a um microorganismo em um indivìduo, kit modular, método para analisar, projetar e/ou modificar um agente capaz de interagir com um sìtio de ligação de molécula imunointerativa anti-gpi glicano, e, uso do agente
AU2003304411A1 (en) 2002-08-01 2005-03-07 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
CA2495121A1 (en) 2002-08-10 2004-02-19 Yale University Nogo receptor antagonists
BRPI0313739B8 (pt) 2002-08-13 2021-07-27 N Dia Inc método para detectar infiltração de líquido amniótico em secreções vaginais e dispositivo para realizar um método de detecção
DE60322719D1 (de) 2002-08-23 2008-09-18 Bayer Healthcare Ag Polypeptid-biomarker zur diagnose von morbus alzheimer
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
DE60325382D1 (de) 2002-09-09 2009-01-29 Arbor Vita Corp Verfahren zur diagnose von gebärmutterhalskrebs
US6774758B2 (en) * 2002-09-11 2004-08-10 Kalyan P. Gokhale Low harmonic rectifier circuit
US20050042621A1 (en) * 2002-09-27 2005-02-24 Affymetrix, Inc. Method for preparing a nucleic acid sample for hybridization to an array
AU2003274629B2 (en) * 2002-10-11 2009-03-12 Zbx Corporation Diagnostic devices
BR0315605A (pt) 2002-10-24 2005-08-30 Sterix Ltd Inibidores da 11-beta-hidroxi esteróide desidrogenase tipo 1 e tipo 2
EP1565745A4 (en) * 2002-11-12 2007-06-27 Strategic Diagnostics Inc ISOLATION AND CONFIRMATION OF ANALYZES FROM TEST EQUIPMENT
US7314750B2 (en) * 2002-11-20 2008-01-01 Affymetrix, Inc. Addressable oligonucleotide array of the rat genome
US7250289B2 (en) * 2002-11-20 2007-07-31 Affymetrix, Inc. Methods of genetic analysis of mouse
EP1594975A4 (en) 2002-12-04 2006-08-02 Applera Corp MULTIPLEX AMPLIFICATION OF POLYNUCLEOTIDES
US20040121334A1 (en) 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
CA2777534A1 (en) * 2002-12-26 2004-07-15 Meso Scale Technologies, Llc Methods, compositions and kits for biomarker extraction
AU2003285724A1 (en) * 2002-12-31 2004-07-22 Pharmacia & Upjohn Company Llc Canine l-pbe sequences
WO2004057940A2 (en) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Canine dioxin/aryl hydrocarbon receptor sequences
WO2004058957A2 (en) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Canine cyp1a2 sequences
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
PT1748074E (pt) 2003-01-17 2012-01-16 Danisco Método para a produção in situ de um emulsificador num alimento
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
MXPA05007654A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US20100143442A1 (en) 2003-02-05 2010-06-10 Queensland University Of Technology Growth factor complexes and modulation of cell migration and growth
AU2003900481A0 (en) 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
US7157551B2 (en) * 2003-02-14 2007-01-02 Cephalon, Inc. Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
CA2558873C (en) 2003-03-07 2015-10-20 New England Medical Center Hospitals, Inc. Treatment of iga1 deposition diseases
WO2004093902A1 (en) * 2003-03-19 2004-11-04 The General Hospital Corporation CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS
AU2003901325A0 (en) 2003-03-21 2003-04-03 Stephen Locarnini Therapeutic, prophylactic and diagnostic agents
AU2004224825A1 (en) * 2003-03-26 2004-10-07 Crc For Asthma Limited Therapeutic and prophylactic compositions and uses therefor
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
ATE517926T1 (de) 2003-04-04 2011-08-15 Yeda Res & Dev Antikörper zur hemmung der aktivität von mmp-2 und mmp-9
RS20050774A (sr) * 2003-04-16 2007-12-31 Biogen Idec Ma Inc., Antagonisti nogo receptora za tretman stanja sa amiloidnim plakovima
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
DE602004024308D1 (de) * 2003-05-27 2010-01-07 Mitsubishi Kagaku Iatron Inc Immunchromatographisches verfahren
US20060246526A1 (en) * 2003-06-02 2006-11-02 Gyros Patent Ab Microfluidic affinity assays with improved performance
US20050025779A1 (en) * 2003-06-12 2005-02-03 Vaxgen, Inc. HIV-1 envelope glycoproteins having unusual disulfide structure
US7910544B2 (en) 2003-07-17 2011-03-22 The General Hospital Corporation Conformationally constrained parthyroid hormone (PTH) analogs
US20050014734A1 (en) * 2003-07-18 2005-01-20 Genovate Biotechnology Co., Ltd. Modulation of interleukin-10 by DHEA
SG145745A1 (en) 2003-08-06 2008-09-29 Senomyx Inc Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
EP1668111A4 (en) 2003-08-08 2008-07-02 Genenews Inc OSTEOARTHRITIS BIOMARKERS AND USES THEREOF
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
JP2007502119A (ja) 2003-08-14 2007-02-08 エクセリクシス, インク. βカテニン経路のモディファイヤーとしてのUPs及び使用方法
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
AU2004274909B8 (en) 2003-09-15 2010-06-10 Oklahoma Medical Research Foundation Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases
CN1902326A (zh) 2003-09-18 2007-01-24 根马布股份公司 用于癌症诊断和治疗的差异性表达的肿瘤特异性多肽
US7378285B2 (en) * 2003-09-22 2008-05-27 Paul Lambotte Devices for the detection of multiple analytes in a sample
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050079484A1 (en) * 2003-10-10 2005-04-14 Heineman William Richard Method of detecting biological materials in liquid
EP1682677B1 (en) 2003-10-21 2012-04-11 Orion Genomics, LLC Differential enzymatic fragmentation
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
PE20090046A1 (es) 2003-11-10 2009-01-26 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
ATE468356T1 (de) 2003-11-25 2010-06-15 Us Gov Health & Human Serv Mutierte anti-cd22-antikörper und immunkonjugate
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7863053B2 (en) * 2003-12-23 2011-01-04 Kimberly-Clark Worldwide, Inc. Swab-based diagnostic systems
AU2004308964B2 (en) 2003-12-23 2010-09-16 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
US7098040B2 (en) * 2003-12-23 2006-08-29 Kimberly-Clark Worldwide, Inc. Self-contained swab-based diagnostic systems
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
KR101169265B1 (ko) 2003-12-24 2012-08-02 대니스코 에이/에스 단백질
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
AU2005206388A1 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods and systems for annotating biomolecular sequences
US7638093B2 (en) * 2004-01-28 2009-12-29 Dnt Scientific Research, Llc Interrupted flow rapid confirmatory immunological testing device and method
US20080227220A1 (en) * 2004-01-29 2008-09-18 Maartje-Maria Franse Lateral Flow Binding Assay
EP1730173A4 (en) * 2004-02-18 2008-10-08 Merck & Co Inc NUCLEIC ACID MOLECULES COORDINATING TO NEW MACHINE CALCIUM CHANNEL PROPERTIES ACTIVATED BY LOW VOLTAGES, DESCRIBED AS ALPHA 1H, PROCEDED PROTEINS, AND METHOD OF USE THEREOF
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP1721011A1 (en) 2004-03-01 2006-11-15 Applera Corporation Methods, compositions and kits for use in polynucleotide amplification
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
EP3175855B1 (en) 2004-03-12 2020-07-15 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using fxr ligands
JP2007530946A (ja) * 2004-03-23 2007-11-01 クイデル コーポレイション ハイブリッド相ラテラルフロー・アッセイ
JP4659025B2 (ja) 2004-04-15 2011-03-30 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 神経系傷害および他の神経障害についての生物マーカーとしての神経タンパク質
EP1742658B1 (en) 2004-04-23 2014-12-24 Zoetis P&U LLC Cellular permissivity factor for viruses, and uses thereof
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
EP2400030B1 (en) 2004-05-18 2016-01-20 The Board of Trustees of the Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
JP4651663B2 (ja) 2004-05-28 2011-03-16 アジェンシス,インコーポレイテッド Pscaタンパク質に結合する抗体および関連分子
WO2005118810A1 (en) 2004-06-03 2005-12-15 Athlomics Pty Ltd Agents and methods for diagnosing stress
ATE428931T1 (de) 2004-06-03 2009-05-15 Meso Scale Technologies Llc Verfahren zur durchführung von vollbluttests
ES2660765T3 (es) 2004-06-21 2018-03-26 The Board Of Trustees Of The Leland Stanford Junior University Genes y rutas expresadas de forma diferencial en trastorno bipolar y/o trastorno depresivo mayor
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7763454B2 (en) 2004-07-09 2010-07-27 Church & Dwight Co., Inc. Electronic analyte assaying device
CN1984982A (zh) 2004-07-16 2007-06-20 丹尼斯科公司 用酶使油脱胶的方法
WO2006007664A1 (en) * 2004-07-22 2006-01-26 Genomics Research Partners Pty Ltd Agents and methods for diagnosing osteoarthritis
CA2579790A1 (en) * 2004-07-30 2006-02-09 Mount Sinai School Of Medicine Of New York University Npc1l1 and npc1l1 inhibitors and methods of use thereof
EP1784510A4 (en) * 2004-08-02 2010-08-04 Janssen Pharmaceutica Nv IRAK1C SPLICE VARIANT AND USE THEREOF
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
US7598080B2 (en) 2004-08-20 2009-10-06 Carl Deirmengian Diagnostic assay for source of inflammation
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
US8691963B2 (en) 2004-08-26 2014-04-08 Engeneic Molecular Delivery Pty. Ltd. Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells
EP1802775B1 (en) 2004-09-14 2010-05-26 The Regents of the University of Colorado Method for treatment with bucindolol based on genetic targeting
DE602005024704D1 (de) 2004-09-18 2010-12-23 Univ Maryland Therapeutische mittel zum targeting des nc ca-atp-kanals und verwendungsverfahren dafür
ATE486606T1 (de) 2004-09-18 2010-11-15 Univ Maryland Therapeutische mittel zum targeting des ncca-atp- kanals und verwendungsverfahren dafür
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
GB0423139D0 (en) * 2004-10-18 2004-11-17 Danisco Enzymes
WO2006047417A2 (en) 2004-10-21 2006-05-04 University Of Florida Research Foundation, Inc. Detection of cannabinoid receptor biomarkers and uses thereof
JP5948627B2 (ja) 2004-10-29 2016-07-20 レイショファーム ゲーエムベーハー 線維芽細胞成長因子(fgf)のリモデリングと糖質ペグ化
US20090104170A1 (en) * 2004-11-02 2009-04-23 Richard William Wyatt Childs Compositions and methods for treating hyperproliferative disorders
EP1655606B1 (en) * 2004-11-05 2011-08-10 F. Hoffmann-La Roche AG Biochemical assay and device
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
JP2008520583A (ja) * 2004-11-15 2008-06-19 マウント シナイ スクール オブ メディスン オブ ニューヨーク ユニバーシティー Wnt自己分泌シグナル伝達を改変するための組成物および方法
JP5026978B2 (ja) 2004-11-18 2012-09-19 エッペンドルフ アレイ テクノロジーズ ソシエテ アノニム マイクロアレイ上での複数標的のリアルタイム定量化
US7465587B2 (en) * 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
ES2356830T3 (es) 2004-12-03 2011-04-13 Schering Corporation Biomarcadores para preselección de pacientes para terapia de anti-igf-1r.
US20060205012A1 (en) * 2004-12-09 2006-09-14 Meso Scale Technologies, Llc Diagnostic test
US7387890B2 (en) * 2004-12-16 2008-06-17 Chembio Diagnostic Systems, Inc. Immunoassay devices and use thereof
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
CA2591659A1 (en) 2004-12-17 2006-06-22 Monash University Regulation of metalloprotease cleavage of cell surface proteins
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
JP4004505B2 (ja) * 2005-01-11 2007-11-07 富士フイルム株式会社 流路部材及びセンサユニット
US9568471B2 (en) 2005-01-25 2017-02-14 The Johns Hopkins University Plasmodium diagnostic assay device
EP1850866A4 (en) 2005-01-27 2009-07-08 Univ California MONOCLONAL THERAPEUTIC ANTIBODIES FOR THE NEUTRALIZATION OF BOTULIN NEUROTOXINES
US20060292700A1 (en) * 2005-06-22 2006-12-28 Naishu Wang Diffused interrupted lateral flow immunoassay device and method
CN103497993A (zh) 2005-02-07 2014-01-08 基因信息公司 轻度骨关节炎生物标志物及其用途
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
RU2413735C2 (ru) 2005-03-31 2011-03-10 Эдженсис, Инк. Антитела и родственные молекулы, связывающиеся с белками 161p2f10b
EP1874958B1 (en) * 2005-04-01 2019-03-27 University of Florida Research Foundation, Incorporated Biomarkers of liver injury
US8048638B2 (en) * 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
DK2645106T4 (da) 2005-04-04 2024-12-02 Biogen Ma Inc Fremgangsmåder til evaluering af et immunrespons på et terapeutisk middel
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
WO2006111029A1 (en) 2005-04-18 2006-10-26 Genesis Genomics Inc. Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
US7803319B2 (en) 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US7858384B2 (en) 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7439079B2 (en) * 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
US7709198B2 (en) 2005-06-20 2010-05-04 Advanced Cell Diagnostics, Inc. Multiplex detection of nucleic acids
US20090264305A1 (en) 2005-07-07 2009-10-22 Athlomics Pty Ltd. Polynucleotide Marker Genes and their Expression, for Diagnosis of Endotoxemia
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
CA2615460A1 (en) * 2005-08-08 2007-02-15 Onconon, Llc Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US20070042504A1 (en) * 2005-08-22 2007-02-22 Yimin Yu Method for determining substance or substances in liquid sample
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
LT1931710T (lt) 2005-08-31 2017-03-27 Merck Sharp & Dohme Corp. Rekombinantiniai anti-il-23 antikūnai
US8193328B2 (en) * 2005-09-08 2012-06-05 Philadelphia Health & Education Corporation Identification of modulators of serine protease inhibitor Kazal and their use as anti-cancer and anti-viral agents
US7608395B2 (en) * 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
WO2007041340A2 (en) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Microfluidic cells with parallel arrays of individual dna molecules
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for diagnosis of preeclamsia
US20070202515A1 (en) * 2005-10-12 2007-08-30 Pathologica, Llc. Promac signature application
US8153444B2 (en) * 2005-10-13 2012-04-10 Auric Enterprises, Llc Immuno gold lateral flow assay
US7344893B2 (en) * 2005-10-13 2008-03-18 Auric Enterprises, Llc Immuno-gold lateral flow assay
US7910381B2 (en) * 2005-10-13 2011-03-22 BioAssay Works Immuno gold lateral flow assay
WO2007048092A2 (en) * 2005-10-17 2007-04-26 Spidertech, A Division Of Stoecker & Associates, A Subsidiary Of The Dermatology Center, Llc Immunoassay for venom detection including noninvasive sample collection
CN101370946B (zh) 2005-10-21 2011-07-20 基因信息股份有限公司 用于使生物标志产物水平与疾病相关联的方法和装置
WO2007053524A2 (en) * 2005-10-28 2007-05-10 The Florida International University Board Of Trustees Horse: human chimeric antibodies
EP1945261A4 (en) 2005-11-07 2010-05-12 Scripps Research Inst COMPOSITIONS AND METHODS FOR CONTROLLING THE SPECIFICITY OF TISSUE FACTOR SIGNALING
ES2534672T3 (es) 2005-11-12 2015-04-27 The Board Of Trustees Of The Leland Métodos relacionados con FGF2 para diagnosticar y tratar la depresión
WO2007061684A1 (en) 2005-11-18 2007-05-31 Board Of Regents, The University Of Texas System Quantification of fusion proteins and their activity from chromosomal translocation
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
CA2630597A1 (en) 2005-12-08 2007-06-14 Novartis Ag Effects of inhibitors of fgfr3 on gene transcription
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
US7279136B2 (en) 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7618810B2 (en) 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
EP2674440B1 (en) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Multivalent immunoglobulin-based bioactive assemblies
CN101529246B (zh) 2005-12-21 2013-05-15 梅索斯卡莱科技公司 分析装置、方法和试剂
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
ES2606015T3 (es) 2005-12-22 2017-03-17 Abbott Molecular Inc. Métodos y combinaciones de marcadores para la detección de la predisposición al cáncer de pulmón
US20090053694A1 (en) * 2005-12-26 2009-02-26 Kriksunov Leo B Photochemically Amplified Bioassay
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
EP1973945A4 (en) 2006-01-16 2009-11-18 Compugen Ltd NEW NUCLEOTIDE AND AMINO ACID SEQUENCES AND METHOD FOR THEIR APPLICATION IN DIAGNOSIS
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
CA2913655A1 (en) 2006-01-27 2007-08-09 Biogen Ma Inc. Nogo receptor antagonists
EP1991577A2 (en) 2006-01-31 2008-11-19 Parkinson, John F. Modulation of mdl-1 activity for treatment of inflammatory disease
WO2007087689A1 (en) 2006-02-03 2007-08-09 Crc For Asthma And Airways Ltd A method of modulating cellular activity and agents for use therein
WO2007092563A2 (en) 2006-02-08 2007-08-16 Genzyme Corporation Gene therapy for niemann-pick disease type a
US20070224701A1 (en) * 2006-02-16 2007-09-27 Becton, Dickinson And Company Combination vertical and lateral flow immunoassay device
WO2007100770A2 (en) 2006-02-28 2007-09-07 Elan Pharmaceuticals, Inc. Methods of treating inflammatory and autoimmune diseases with natalizumab
WO2007103112A2 (en) 2006-03-03 2007-09-13 Elan Pharmaceuticals, Inc. Methods of treating inflammatory and autoimmune diseases with natalizumab
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
EP3156799B1 (en) 2006-04-04 2024-01-24 Novilux, LLC Analyzer and method for highly sensitive detection of analytes
EP2472258A3 (en) 2006-04-04 2012-11-28 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
EP2010567A2 (en) * 2006-04-07 2009-01-07 The Government of the United States of America as Represented by The Department of Health and Human Services Antibody compositions and methods for treatment of neoplastic disease
KR101387563B1 (ko) 2006-04-21 2014-04-25 세노믹스, 인코포레이티드 고효능의 조미용 향료를 포함하는 식품 조성물 및 이의 제조 방법
FR2900341B1 (fr) * 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
AU2007249620A1 (en) * 2006-05-09 2007-11-22 Musc Foundation For Research Development Detecting diastolic heart failure by protease and protease inhibitor plasma profiling
AU2007269714A1 (en) 2006-07-03 2008-01-10 Charles David Adair Composition for modulating the expression of cell adhesion molecules
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
JP2009544013A (ja) * 2006-07-11 2009-12-10 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント プロテアーゼおよびプロテアーゼ阻害因子のプロファイリングによる心筋梗塞後の心不全の予測
KR101433392B1 (ko) 2006-07-14 2014-08-29 케모센트릭스, 인크. 트리아졸릴 페닐 벤젠설폰아마이드
JP2009545320A (ja) * 2006-08-04 2009-12-24 ザ ジェネラル ホスピタル コーポレイション 副甲状腺ホルモン(pth)のポリペプチド誘導体
US20110184747A1 (en) * 2006-08-09 2011-07-28 Carmen Bozic Method for distribution of a drug
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
EP2423333A1 (en) 2006-08-25 2012-02-29 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的tNOXアイソフォーム及び方法
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US7985542B2 (en) 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
EP2469282A1 (en) 2006-09-08 2012-06-27 University of Oxford Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
EP2074230B1 (en) * 2006-10-11 2012-11-28 Janssen Pharmaceutica NV Compositions and methods for treating and diagnosing irritable bowel syndrome
EP1912067A1 (en) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Method for quantification of a target compound obtained from a biological sample upon chips
EP2076591A2 (en) 2006-10-20 2009-07-08 Danisco US, INC., Genencor Division Polyol oxidases
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
JP5057402B2 (ja) * 2006-10-26 2012-10-24 アボット・ラボラトリーズ 内在性の抗分析物抗体を含有する試料中の分析物の免疫アッセイ
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
AU2007310787A1 (en) 2006-10-27 2008-05-02 Janssen Pharmaceutica Nv A method for profiling kinase inhibitors
EP2092074A4 (en) 2006-11-02 2010-06-09 Univ Yale EVALUATION OF THE EFFECTIVENESS OF EGGS
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
WO2008067547A2 (en) 2006-11-30 2008-06-05 Research Development Foundation Improved immunoglobulin libraries
US8473216B2 (en) * 2006-11-30 2013-06-25 Fluidigm Corporation Method and program for performing baseline correction of amplification curves in a PCR experiment
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
KR20090088950A (ko) 2006-12-14 2009-08-20 쉐링 코포레이션 가공된 항-tslp 항체
US8377379B2 (en) 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
US7935538B2 (en) 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
WO2008085895A2 (en) * 2007-01-04 2008-07-17 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
BRPI0806565A2 (pt) * 2007-01-11 2014-05-06 Erasmus University Medical Center Captura de conformação de cromossomo circular
EP2111224B1 (en) 2007-01-12 2016-07-13 University of Maryland, Baltimore Targeting ncca-atp channel for organ protection following ischemic episode
JP5124593B2 (ja) 2007-01-25 2013-01-23 デュポン ニュートリション バイオサイエンシーズ エーピーエス 形質転換バチルス・リケニフォルミス細胞からの脂質アシルトランスフェラーゼの製造
JP5175864B2 (ja) 2007-01-26 2013-04-03 ユニバーシティー オブ ルイヴィル リサーチ ファウンデーション,インコーポレーテッド 疾患の検出及び特徴付けのために自己抗体を検出する方法
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 il-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 il-32측정법
AU2008218968B2 (en) 2007-02-23 2013-10-17 Merck Sharp & Dohme Llc Engineered anti-IL-23p19 antibodies
SG178804A1 (en) 2007-02-23 2012-03-29 Schering Corp Engineered anti-il-23p19 antibodies
JP5238723B2 (ja) 2007-02-28 2013-07-17 メルク・シャープ・アンド・ドーム・コーポレーション 操作された抗il−23r抗体
US7776618B2 (en) * 2007-03-01 2010-08-17 Church & Dwight Co., Inc. Diagnostic detection device
WO2008110006A1 (en) 2007-03-12 2008-09-18 Miraculins Inc. Biomarkers of prostate cancer and uses thereof
WO2008118324A2 (en) 2007-03-26 2008-10-02 Macrogenics, Inc. Composition and method of treating cancer with an anti-uroplakin ib antibody
US20100143905A1 (en) * 2007-03-29 2010-06-10 Lane Michael J Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
SI2865755T1 (sl) 2007-03-30 2017-06-30 Engeneic Molecular Delivery Pty Ltd. Intaktne minicelice, ki so izvedene iz bakterij in vključujejo regulatorno RNA
CN101680034B (zh) 2007-04-06 2015-12-16 贝克顿·迪金森公司 用于鉴定碳青霉烯酶基因的组合物和方法
JP5926487B2 (ja) 2007-04-13 2016-05-25 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド ErbB療法に耐性である癌を治療するための方法
US8003314B2 (en) * 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
CA2684998A1 (en) 2007-04-30 2009-01-29 Nanogen, Inc. Multianalyte assay
DK2155789T3 (da) 2007-05-01 2013-10-21 Res Dev Foundation Immunoglobulin-Fc-biblioteker
EP2152730A4 (en) * 2007-05-02 2011-08-03 Univ Emory ENLARGEMENT OF GLYCOPROTEININCORPORATION IN VIRUSUAL PARTICLES
MX2009013269A (es) 2007-06-05 2010-04-21 Univ Yale Inhibidores de receptor de cinasas de tirosina y metodos de uso de los mismos.
CN103254308B (zh) 2007-06-15 2015-01-21 厦门大学 H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
US7776877B2 (en) * 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (en) * 2007-06-28 2008-12-31 University Of Saskatchewan Immunomodulatory compositions and methods for treating disease with modified host defense peptides
KR101969689B1 (ko) 2007-07-12 2019-04-16 케모센트릭스, 인크. 염증의 치료를 위한 ccr2 조절물질로서 융합된 헤테로아릴 피리딜과 페닐 벤젠술폰아마이드
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
MX353986B (es) * 2007-08-01 2017-11-06 Massachusetts Gen Hospital Metodos de analisis y seleccion usando receptores acoplados a proteina g y composiciones relacionadas.
EP2185718B1 (en) 2007-08-03 2017-10-04 MUSC Foundation For Research Development Human monoclonal antibodies and methods for producing the same
EP2185726B1 (en) 2007-08-06 2014-01-08 Orion Genomics, LLC Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene
AU2008296733B2 (en) 2007-08-08 2013-07-11 The Board Of Regents Of The University Of Texas System VEGFR-1/NRP-1 targeting peptides
WO2009023676A1 (en) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Microarray system with improved sequence specificity
WO2009023733A1 (en) * 2007-08-13 2009-02-19 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
WO2009029550A2 (en) * 2007-08-24 2009-03-05 Singulex, Inc. Highly sensitive system and methods for analysis of prostate specific antigen (psa)
PL2769729T3 (pl) 2007-09-04 2019-09-30 Compugen Ltd. Polipeptydy i polinukleotydy i ich zastosowanie jako cel dla leków do wytwarzania leków i środków biologicznych
US8053198B2 (en) * 2007-09-14 2011-11-08 Meso Scale Technologies, Llc Diagnostic methods
EP2511708B1 (en) 2007-10-05 2016-09-14 Affymetrix, Inc. Highly multiplexed particle-based assays
US8535617B2 (en) * 2007-11-30 2013-09-17 Kimberly-Clark Worldwide, Inc. Blood cell barrier for a lateral flow device
US20090155753A1 (en) * 2007-12-14 2009-06-18 Kimberly-Clark Worldwide, Inc. Behavior Tracking with Tracking Pods
US9103796B2 (en) * 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
WO2009117033A2 (en) 2007-12-19 2009-09-24 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
MX2010007530A (es) 2008-01-10 2010-11-10 Res Dev Foundation Vacunas y diagnosticos para ehrlichiosis.
US20110052501A1 (en) * 2008-01-31 2011-03-03 Liat Dassa Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US20090196852A1 (en) * 2008-02-04 2009-08-06 Watkinson D Tobin Compositions and methods for diagnosing and treating immune disorders
SI2252312T1 (sl) 2008-02-07 2014-08-29 Cornell University, Postopki za preprečevanje ali zdravljenje insulinske rezistence
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
US20110136166A1 (en) * 2008-03-14 2011-06-09 Eastern Virginia Medical School Imaging Mass Spectrometry for Improved Prostrate Cancer Diagnostics
US8993231B2 (en) * 2008-03-18 2015-03-31 Marshall University Research Corporation Methods for stem cell production and therapy
JP5938690B2 (ja) 2008-03-28 2016-06-22 エムディーエヌエー ライフ サイエンシズ インコーポレイテッド 異常型ミトコンドリアdna、関連融合転写物およびそのハイブリダイゼーションプローブ
EP2107125A1 (en) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Real-time PCR of targets on a micro-array
DK2247304T3 (en) 2008-04-02 2016-09-26 Macrogenics Inc Her2 / neu-specific antibodies and methods of use thereof
CN106349390B (zh) 2008-04-02 2019-12-10 宏观基因有限公司 Bcr-复合体-特异性抗体和其使用方法
DK3567363T3 (da) 2008-04-11 2022-04-25 Meso Scale Technologies Llc Prøvningsindretninger, -fremgangsmåder og reagenser
GB0807161D0 (en) * 2008-04-18 2008-05-21 Danisco Process
US20090269780A1 (en) * 2008-04-23 2009-10-29 Luminex Corporation Method for Creating a Standard for Multiple Analytes Found in a Starting Material of Biological Origin
WO2009132124A2 (en) 2008-04-24 2009-10-29 The Trustees Of Columbia University In The City Of New York Geometric patterns and lipid bilayers for dna molecule organization and uses thereof
DK2281034T3 (en) 2008-04-30 2016-01-25 Dupont Nutrition Biosci Aps A method using alcohol dehydrogenase Pseudoglucanobacter saccharoketogenes
US9243030B2 (en) * 2008-05-22 2016-01-26 Centre National De La Recherche Scientifique (Cnrs) Optically pure compounds for improved therapeutic efficiency
WO2010033279A2 (en) 2008-06-04 2010-03-25 Macrogenics, Inc. Antibodies with altered binding to fcrn and methods of using same
WO2010011860A1 (en) * 2008-07-23 2010-01-28 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
NO2324360T3 (en:Method) 2008-08-11 2018-06-30
BRPI0823016A2 (pt) 2008-08-18 2016-05-24 Seoul Nat Univ Ind Foundation processo para o controle de metástase de câncer ou para migração de célula cancerosa por modulação do nível celular de lisil trna sintétase
GB2464183A (en) * 2008-09-19 2010-04-14 Singulex Inc Sandwich assay
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
US8101813B2 (en) * 2008-10-30 2012-01-24 Kimberly-Clark Worldwide, Inc. Training progress indicator
JP5805538B2 (ja) 2008-11-07 2015-11-04 リサーチ ディベロップメント ファウンデーション Cripto/GSP78複合体形成およびシグナル伝達を阻害するための組成物および方法
WO2010061393A1 (en) 2008-11-30 2010-06-03 Compugen Ltd. He4 variant nucleotide and amino acid sequences, and methods of use thereof
EP2370092A1 (en) 2008-12-03 2011-10-05 Research Development Foundation Modulation of olfml-3 mediated angiogenesis
EP2194381B1 (de) 2008-12-03 2015-12-02 Roche Diagnostics GmbH Testelement mit kombinierter Kontroll- und Kalibrationszone
US8431775B2 (en) 2008-12-04 2013-04-30 Pioneer Hi Bred International Inc Methods and compositions for enhanced yield by targeted expression of knotted1
CA2745904C (en) 2008-12-05 2014-07-08 Abraxis Bioscience Llc Sparc binding peptides and uses thereof
AU2009325878B2 (en) 2008-12-08 2014-01-16 Compugen Ltd. TMEM154 polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US20120003664A1 (en) 2008-12-09 2012-01-05 Uffe Lovborg Method for evaluating pre-treatment
WO2010068747A1 (en) 2008-12-12 2010-06-17 University Of Florida Research Foundation, Inc. Cell-based detection of apf through its interaction with ckap4 for diagnosis of interstitial cystitis
WO2010068757A1 (en) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions
US8692873B2 (en) 2009-01-15 2014-04-08 Alverix, Inc. Video-frame data receiver with low frame capture rate
US8422740B2 (en) 2009-01-15 2013-04-16 Scott Dylewski Methods for determining a liquid front position on a test strip
ES2805347T3 (es) 2009-02-11 2021-02-11 Caris Mpi Inc Perfilado molecular de tumores
EP2396429B1 (en) 2009-02-11 2015-05-27 Orion Genomics, LLC Combinations of polymorphisms for determining allele-specific expression of igf2
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
US20110306069A1 (en) 2009-02-19 2011-12-15 Qingyu Wu Corin As A Marker For Heart Failure
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
KR101720555B1 (ko) 2009-03-27 2017-03-29 엠디엔에이 라이프 사이언시즈 인코퍼레이티드 이상 미토콘드리아 디엔에이, 관련된 융합 전사물 및 번역 산물 및 이에 대한 하이브리드화 탐침
DK2411410T3 (en) * 2009-03-27 2015-09-07 Gojo Ind Inc Compositions and methods for screening and use of compounds which counteract the track-surface interactions
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
AU2010239131A1 (en) 2009-04-21 2011-11-17 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
WO2010124689A1 (en) 2009-05-01 2010-11-04 Dako Denmark A/S New antibody cocktail
US20120046197A1 (en) 2009-05-01 2012-02-23 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
WO2010132447A2 (en) 2009-05-11 2010-11-18 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US20120058916A1 (en) 2009-05-13 2012-03-08 Meso Scale Technologies, Llc. Diagnostic methods for liver disorders
EP2430451B1 (en) 2009-05-14 2014-08-13 The Chancellors, Masters and Scholars of the University of Oxford Clinical diagnosis of hepatic fibrosis / cirrhosis using low abundant human plasma protein biomarkers
WO2010134035A1 (en) 2009-05-19 2010-11-25 Danisco A/S Use
EP2432499A2 (en) 2009-05-20 2012-03-28 Schering Corporation Modulation of pilr receptors to treat microbial infections
RU2566064C2 (ru) 2009-06-02 2015-10-20 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Идентификация низкомолекулярных соединений, распознаваемых антителами у индивидуумов с нейродегенеративными заболеваниями
US8802427B2 (en) * 2009-06-09 2014-08-12 Church & Dwight Co., Inc. Female fertility test
EP2446027A1 (en) 2009-06-25 2012-05-02 Danisco A/S Protein
MX392642B (es) 2009-07-17 2025-03-19 Bioatla Llc Seleccion y desarrollo integrados simultaneos del desempeño y la expresion de proteinas/anticuerpos en hospederos de produccion.
JP5816173B2 (ja) 2009-07-27 2015-11-18 メソ スケール テクノロジーズ エルエルシー 分析装置、消耗品及び方法
ES2581178T3 (es) 2009-07-29 2016-09-01 Pharnext Nuevas herramientas de diagnóstico para enfermedad de Alzheimer
CN102574924A (zh) 2009-09-03 2012-07-11 先灵公司 抗-gitr抗体
US8900850B2 (en) * 2009-09-17 2014-12-02 Michael J. Lane Lateral flow based methods and assays for rapid and inexpensive diagnostic tests
WO2011038403A1 (en) 2009-09-28 2011-03-31 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
WO2011044186A1 (en) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Human single-chain t cell receptors
ES2989929T3 (es) 2009-10-11 2024-11-28 Biogen Ma Inc Ensayos relacionados con anti-VLA-4
WO2011056688A2 (en) 2009-10-27 2011-05-12 Caris Life Sciences, Inc. Molecular profiling for personalized medicine
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
CN108707584A (zh) 2009-11-17 2018-10-26 Musc研究发展基金会 针对人核仁素的人单克隆抗体
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
RU2012127364A (ru) 2009-11-30 2014-01-10 Квинсленд Юниверсити Оф Текнолоджи Химеры фибронектин: фактор роста
EP2507265B1 (en) 2009-12-01 2016-05-11 Compugen Ltd. Antibody specific for heparanase splice variant T5 and its use.
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US20110136141A1 (en) * 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US8183002B2 (en) * 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US8691227B2 (en) 2009-12-17 2014-04-08 Merck Sharp & Dohme Corp. Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
SMT201800148T1 (it) 2010-01-11 2018-05-02 Biogen Ma Inc Saggio per anticorpi del virus jc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
AU2011354597B2 (en) 2010-01-26 2016-09-22 Bioregency Inc. Compositions and methods relating to argininosuccinate synthetase
WO2011092700A1 (en) 2010-01-27 2011-08-04 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
WO2011094669A1 (en) 2010-01-29 2011-08-04 Advanced Cell Diagnostics, Inc. Methods of in situ detection of nucleic acids
CN102740976B (zh) 2010-01-29 2016-04-20 精密公司 取样-应答微流体盒
US8574832B2 (en) 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對alk抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
EP2533804B1 (en) 2010-02-08 2018-04-11 Agensys, Inc. Antibody drug conjugates (adc) that bind to 161p2f10b proteins
WO2011106738A2 (en) 2010-02-25 2011-09-01 Fred Hutchinson Cancer Research Center Use of tcr clonotypes as biomarkers for disease
US20130058915A1 (en) 2010-03-02 2013-03-07 Children's Medica Center Corporation Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
US10706955B2 (en) 2010-03-23 2020-07-07 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
WO2013040142A2 (en) 2011-09-16 2013-03-21 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US9631018B2 (en) 2010-03-26 2017-04-25 The Trustees Of Dartmouth College Vista regulatory T cell mediator protein, vista binding agents and use thereof
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
GB2491795A (en) 2010-04-06 2012-12-12 Massachusetts Inst Technology Gene-expression profiling with reduced numbers of transcript measurements
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
EP3848394A1 (en) 2010-04-09 2021-07-14 Critical Care Diagnostics, Inc. Soluble human st-2 antibodies and assays
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
WO2011133450A2 (en) 2010-04-19 2011-10-27 Meso Scale Technologies, Llc. Serology assays
US10295472B2 (en) 2010-05-05 2019-05-21 Alverix, Inc. Assay reader operable to scan a test strip
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
JP2013525814A (ja) 2010-05-07 2013-06-20 アッヴィ・インコーポレイテッド 標的化チロシンキナーゼインヒビターでの治療に対する感受性の予測方法
MX358161B (es) 2010-05-13 2018-08-06 The General Hospital Corp Star Analogos de hormona paratiroidea y usos para los mismos.
US20110287458A1 (en) 2010-05-18 2011-11-24 The Texas A&M University System Method and composition for the diagnosis and monitoring of inflammatory diseases
CN103025885B (zh) 2010-05-26 2016-01-20 伊利诺伊大学评议会 用于检测和定量宽范围分析物的个人葡萄糖计
US8383580B2 (en) 2010-06-10 2013-02-26 The Regents Of The University Of Michigan Methods of administering lipocalins to treat metabolic disorders and cardiovascular diseases
EP3327035A1 (en) 2010-06-22 2018-05-30 Precision Biologics Inc. Colon and pancreas cancer specific antigens and antibodies
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
EP2407242A1 (en) 2010-07-13 2012-01-18 Dublin City University Direct clone analysis and selection technology
EP3435087B1 (en) 2010-07-16 2023-11-08 BioAtla, Inc. Novel methods of protein evolution
CN103153467A (zh) 2010-07-16 2013-06-12 范德比尔特大学 用于提取、浓缩和检测分子物类的使用表面张力阀的低资源处理器
JP5813111B2 (ja) 2010-07-23 2015-11-17 ルミネックス コーポレーション イムノアッセイにおける試薬の反応性を制御するためのコカップリング
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
US9018434B2 (en) 2010-08-06 2015-04-28 Kimberly-Clark Worldwide, Inc. Absorbent articles with intricate graphics
USD656852S1 (en) 2010-08-06 2012-04-03 Kimberly-Clark Worldwide, Inc. Wetness indicator
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US8999335B2 (en) 2010-09-17 2015-04-07 Compugen Ltd. Compositions and methods for treatment of drug resistant multiple myeloma
AU2011305696A1 (en) 2010-09-20 2013-05-02 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
US9068014B2 (en) 2010-09-23 2015-06-30 Precision Biologics, Inc. Colon and pancreas cancer peptidomimetics
US20140004510A1 (en) 2010-09-24 2014-01-02 Massachusetts Eye And Ear Infirmary Methods and compositions for prognosing and/or detecting age-related macular degeneration
EA201790850A1 (ru) 2010-09-29 2017-11-30 Эдженсис, Инк. Конъюгаты антитело-лекарственное средство (adc), связывающиеся с белками 191p4d12
WO2012045750A2 (en) 2010-10-04 2012-04-12 Centre National De La Recherche Scientifique (Cnrs) Compositions comprising multivalent synthetic ligands of surface nucleolin and glycosaminoglycans
EP2441520A1 (en) 2010-10-12 2012-04-18 Eppendorf AG Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay
CA2814680C (en) 2010-10-14 2021-11-16 Meso Scale Technologies, Llc Reagent storage in an assay device
EP2630260B1 (en) 2010-10-21 2015-11-18 Advanced Cell Diagnostics, Inc. An ultra sensitive method for in situ detection of nucleic acids
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
US9220640B2 (en) 2010-12-30 2015-12-29 Kimberly-Clark Worldwide, Inc. Absorbent article including two dimensional code made from an active graphic
AU2011352207B2 (en) 2010-12-31 2016-03-03 Bioatla, Llc Comprehensive monoclonal antibody generation
US20120196294A1 (en) 2011-01-17 2012-08-02 Life Technologies Corporation Workflow for detection of ligands using nucleic acids
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
EP2477032A1 (en) 2011-01-18 2012-07-18 Baxter International Inc Measurement of anti-amyloid antibodies in human blood
KR20130139153A (ko) 2011-01-18 2013-12-20 백스터 인터내셔널 인코포레이티드 인간 혈액 중 항-베타 아밀로이드 항체의 측정
US20120214152A1 (en) 2011-01-28 2012-08-23 Xiao-Jun Ma Rnascope® hpv assay for determining hpv status in head and neck cancers and cervical lesions
CA2826467C (en) 2011-02-07 2019-11-12 Research Development Foundation Engineered immunoglobulin fc polypeptides
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
EP2678042B1 (en) 2011-02-23 2018-05-09 The Board of Trustees of the University of Illionis Amphiphilic dendron-coils, micelles thereof and uses
AU2012226530B2 (en) 2011-03-08 2016-12-01 King Abdullah University Of Science And Technology Molecular biomarker set for early detection of ovarian cancer
EP2684048B1 (en) 2011-03-11 2018-10-03 Board of Regents of the University of Nebraska Biomarker for coronary artery disease
CN103476949A (zh) 2011-03-28 2013-12-25 诺瓦提斯公司 与细胞周期蛋白依赖性激酶抑制剂相关的标志物
MY186591A (en) 2011-04-01 2021-07-29 Immunogen Inc Methods for increasing efficacy of folri cancer therapy
WO2012138941A1 (en) 2011-04-05 2012-10-11 Longevity Biotech, Inc. Compositions comprising glucagon analogs and methods of making and using the same
NZ616308A (en) 2011-04-08 2016-03-31 Biogen Ma Inc Biomarkers predictive of therapeutic responsiveness to ifnβ and uses thereof
JP6027092B2 (ja) 2011-04-08 2016-11-16 ダニスコ・ユーエス・インク 組成物
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
SG10201603034TA (en) 2011-04-15 2016-05-30 Compugen Ltd Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
WO2012161288A1 (en) 2011-05-20 2012-11-29 Abbott Japan Co. Ltd. Immunoassay methods and reagents for decreasing nonspecific binding
JP6457263B2 (ja) 2011-05-20 2019-01-23 オリゴメリックス インコーポレイテッド タウプロテアーゼ組成物および使用方法
CA2837184C (en) 2011-05-25 2021-09-21 Innate Pharma, S.A. Anti-kir antibodies for the treatment of inflammatory and autoimmune disorders
KR102039751B1 (ko) 2011-05-31 2019-11-01 바이오젠 엠에이 인코포레이티드 Pml의 위험을 판단하는 방법
CA2839451A1 (en) 2011-06-27 2013-01-03 The Jackson Laboratory Methods and compositions for treatment of cancer and autoimmune disease
WO2013001517A1 (en) 2011-06-30 2013-01-03 Compugen Ltd. Polypeptides and uses thereof for treatment of autoimmune disorders and infection
WO2013010170A1 (en) 2011-07-14 2013-01-17 Lovell Mark A Process for detection of alzheimer's disease from a serum sample
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
CA2842321C (en) 2011-07-18 2022-05-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
AU2012294814A1 (en) 2011-08-05 2014-02-27 Research Development Foundation Improved methods and compositions for modulation of Olfml3 mediated angiogenesis
US9556281B2 (en) 2011-08-15 2017-01-31 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein A
AU2012298884B2 (en) 2011-08-23 2017-11-16 Foundation Medicine, Inc. Novel KIF5B-RET fusion molecules and uses thereof
EP2758775B1 (en) 2011-09-22 2017-08-16 Medicinal Bioconvergence Research Center Novel use of leucyl trna synthetase
EP2761294B1 (en) 2011-09-29 2019-02-27 Meso Scale Technologies, LLC Biodosimetry panels and methods
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013056178A2 (en) 2011-10-14 2013-04-18 Foundation Medicine, Inc. Novel estrogen receptor mutations and uses thereof
WO2013059740A1 (en) 2011-10-21 2013-04-25 Foundation Medicine, Inc. Novel alk and ntrk1 fusion molecules and uses thereof
US20130164217A1 (en) 2011-12-21 2013-06-27 Meso Scale Technologies, Llc Method of diagnosing, preventing and/or treating dementia & related disorders
JP2015505245A (ja) 2011-12-29 2015-02-19 ベイラー リサーチ インスティテュートBaylor Research Institute 川崎病のためのバイオマーカー
WO2013106458A2 (en) 2012-01-09 2013-07-18 Micronics, Inc. Microfluidic reactor system
WO2013112216A1 (en) 2012-01-24 2013-08-01 Cd Diagnostics, Llc System for detecting infection in synovial fluid
GB201201314D0 (en) 2012-01-26 2012-03-07 Isis Innovation Composition
BR112014018481A2 (pt) 2012-02-01 2017-07-04 Compugen Ltd anticorpo monoclonal ou policlonal ou um fragmento de ligação a antígeno do mesmo, polinucleotídeo, anticorpo monoclonal, vetor, hibridoma, anticorpo, hibridoma 5166-2 e/ou 5166-9, anticorpo ou fragmento de ligação a antígeno, composição farmacêutica, uso do anticorpo ou fragmento de ligação a anticorpo, método para tratar câncer, método para diagnosticar câncer em um indivíduo, anticorpo, método, composição ou uso
US9567642B2 (en) 2012-02-02 2017-02-14 Massachusetts Institute Of Technology Methods and products related to targeted cancer therapy
US9404923B2 (en) 2012-02-07 2016-08-02 Intuitive Biosciences, Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
SG11201405241VA (en) 2012-02-29 2014-09-26 Chemocentryx Inc Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists
SI2828284T1 (sl) 2012-03-20 2019-10-30 Biogen Ma Inc Virus JC nevtralizirajoča protitelesa
US10024860B2 (en) 2012-03-28 2018-07-17 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
WO2013148259A1 (en) 2012-03-28 2013-10-03 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
AU2013252888B2 (en) 2012-04-26 2018-06-14 University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during Staphylococcus aureus disease
EP2847231B1 (en) 2012-05-10 2019-07-10 Bioatla LLC Multi-specific monoclonal antibodies
BR112014029274B1 (pt) 2012-05-24 2022-02-15 Mountgate Innotech (Hk) Limited Anticorpo isolado, composição farmacêutica, uso do anticorpo, e, kit para tratar infecção rábica
ES2786128T3 (es) 2012-06-01 2020-10-08 Icahn School Med Mount Sinai Niveles de ceramida en el tratamiento y prevención de infecciones
WO2014039983A1 (en) 2012-09-07 2014-03-13 The Trustees Of Dartmouth College Vista modulators for diagnosis and treatment of cancer
EP2864500B1 (en) 2012-06-22 2018-08-22 HTG Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
WO2013192504A1 (en) 2012-06-22 2013-12-27 The Trustees Of Dartmouth College Novel vista-ig constructs and the use of vista-ig for treatment of autoimmune, allergic and inflammatory disorders
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
ES2776365T3 (es) 2012-07-09 2020-07-30 Novartis Ag Biomarcadores asociados con inhibidores de CDK
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
WO2014014788A2 (en) 2012-07-18 2014-01-23 President And Fellows Of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
KR102250696B1 (ko) 2012-07-27 2021-05-12 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 T 세포 수용체 조작
HUE045880T2 (hu) 2012-07-31 2020-01-28 Novartis Ag A humán double minute 2 (MDM2) inhibitorra való érzékenységgel összefüggõ markerek
EP2880448B1 (en) 2012-08-03 2022-06-29 Foundation Medicine, Inc. Human papilloma virus as predictor of cancer prognosis
WO2014032021A1 (en) 2012-08-23 2014-02-27 Agensys, Inc. Antibody drug conjugates (adc) that bind to 158p1d7 proteins
WO2014043633A1 (en) 2012-09-17 2014-03-20 Agios Pharmaceuticals, Inc. Use of e-cadherin and vimentin for selection of treatment responsive patients
EP4356927A3 (en) 2012-10-12 2024-10-02 Arizona Board of Regents on behalf of Arizona State University Antibody based reagents that specifically recognize toxic oligomeric forms of tau
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
WO2014062635A1 (en) 2012-10-19 2014-04-24 Novartis Ag Markers for acute lymphoblastic leukemia
EP2909230B1 (en) 2012-10-19 2019-05-22 Danisco US Inc. Stabilization of biomimetic membranes
WO2014066590A1 (en) 2012-10-24 2014-05-01 Research Development Foundation Jam-c antibodies and methods for treatment of cancer
EP2911692B1 (en) 2012-10-26 2019-08-21 The University of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
WO2014071358A2 (en) 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel ntrk1 fusion molecules and uses thereof
HK1214831A1 (zh) 2012-11-05 2016-08-05 Foundation Medicine, Inc. 新型融合分子及其应用
KR20150087270A (ko) 2012-11-05 2015-07-29 프로나이 테라퓨틱스, 인코포레이티드 Bcl2 발현 조절에 의한 암치료용 바이오마커 이용 방법
CA2891972A1 (en) 2012-11-21 2014-06-12 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
EA029531B1 (ru) 2012-11-21 2018-04-30 Аджиос Фармасьютикалз, Инк. Соединения, ингибирующие глутаминазу, и содержащие эти соединения фармацевтические композиции и их применение
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
EP3549674B1 (en) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Low elasticity films for microfluidic use
WO2014100725A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
KR102102123B1 (ko) 2012-12-21 2020-04-20 퍼킨엘머 헬스 사이언시즈, 아이엔씨. 유체 공학 회로 및 관련 제조 방법
NZ709828A (en) 2012-12-28 2019-07-26 Prec Biologics Inc Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
BR112015016027A2 (pt) 2013-01-02 2017-07-11 N Dia Inc método para prever o tempo de parto (ttd), método para determinar o risco de parto prematuro, método para determinar o risco de uma mulher grávida romper espontaneamente a membrana corioaminiótica e kit
CA2896541C (en) 2013-01-04 2020-04-21 Ian Chamberlin Assay apparatuses, methods and reagents
US10980804B2 (en) 2013-01-18 2021-04-20 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
US8968677B2 (en) 2013-01-22 2015-03-03 Quantum Design International, Inc. Frazil ice conjugate assay device and method
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
US20140309263A1 (en) 2013-02-01 2014-10-16 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
US20140221368A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
JP6466855B2 (ja) 2013-02-01 2019-02-06 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ゲノムアセンブリ及びハプロタイプフェージングの方法
US20140221325A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Glomerulonephritis biomarkers
WO2014121077A2 (en) 2013-02-01 2014-08-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs)
US20160008282A1 (en) 2013-02-22 2016-01-14 The Board Of Trustees Of The Universityof Illinois Transdermal Drug Delivery Using Amphiphilic Dendron-Coil Micelles
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與wnt抑制劑相關之標記
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
WO2014159242A1 (en) 2013-03-14 2014-10-02 Novartis Ag Notch 3 mutants and uses thereof
EP2970479B1 (en) 2013-03-14 2019-04-24 Novartis AG Antibodies against notch 3
EP2968469A4 (en) 2013-03-15 2016-08-31 Longevity Biotech Inc PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME
US20160039917A1 (en) 2013-03-15 2016-02-11 Velo Bio, Llc Method for Treating Eclampsia and Preeclampsia
AU2014233885B2 (en) 2013-03-15 2018-08-09 GLAdiator Biosciences, Inc. Gla domains as targeting agents
EP3404116B1 (en) 2013-03-15 2022-10-19 The University of Chicago Methods and compositions related to t-cell activity
US20160051693A1 (en) 2013-03-21 2016-02-25 Genisphere, Llc Cellular Delivery of DNA Intercalating Agents
JP6565121B2 (ja) 2013-03-21 2019-08-28 ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン 代謝障害を治療する方法
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2014172390A2 (en) 2013-04-15 2014-10-23 Cedars-Sinai Medical Center Methods for detecting cancer metastasis
US9588114B2 (en) 2013-04-23 2017-03-07 Montecito Bio Sciences Ltd Flow through testing system with pressure indicator
WO2014176047A1 (en) 2013-04-25 2014-10-30 Novartis Ag Markers for ezh2 inhibitors
US10246708B2 (en) 2013-05-06 2019-04-02 Alnylam Pharmaceuticals, Inc. Dosages and methods for delivering lipid formulated nucleic acid molecules
CA2911308C (en) 2013-05-07 2021-10-19 Micronics, Inc. Device for preparation and analysis of nucleic acids
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN105189750B (zh) 2013-05-07 2020-07-28 珀金埃尔默健康科学有限公司 使用粘土矿物和碱性溶液制备含核酸样品的方法
GB201308658D0 (en) 2013-05-14 2013-06-26 Isis Innovation Antibodies
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
EP3004334A4 (en) 2013-05-28 2016-12-21 Biogen Ma Inc METHOD FOR ASSESSING A PML RISK
US9442051B2 (en) * 2013-06-10 2016-09-13 Yingjian Wang Methods to accelerate the binding of biological molecules
EP3587585B1 (en) 2013-06-12 2021-03-24 The General Hospital Corporation Methods, kits, and systems for multiplexed detection of target molecules and uses thereof
PL3010519T3 (pl) 2013-06-18 2021-09-27 Dnatrix, Inc. Adenowirus onkolityczny do zastosowania w leczeniu nowotworu mózgu
CA2916694C (en) 2013-06-28 2023-01-17 Baylor Research Institute Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis
AU2014290044B2 (en) 2013-07-17 2020-10-29 Foundation Medicine, Inc. Methods of treating urothelial carcinomas
WO2015017552A1 (en) 2013-08-01 2015-02-05 Agensys, Inc. Antibody drug conjugates (adc) that bind to cd37 proteins
US20150038365A1 (en) 2013-08-01 2015-02-05 Meso Scale Technologies, Llc Lung cancer biomarkers
CN106659909B (zh) 2013-08-21 2022-01-11 德克萨斯州大学系统董事会 用于靶向连接蛋白半通道的组合物和方法
PT3038650T (pt) 2013-08-30 2021-08-25 Immunogen Inc Anticorpos e ensaios para a deteção do recetor de folato 1
WO2015038978A1 (en) 2013-09-13 2015-03-19 Symbolics, Llc Lateral flow assays using two dimensional test and control signal readout patterns
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
CA2925004C (en) 2013-10-03 2019-04-30 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
WO2015063604A2 (en) 2013-11-01 2015-05-07 Imberti Luisa BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
CA2965327C (en) 2013-11-08 2023-05-09 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
EP3068783B1 (en) 2013-11-15 2020-09-23 The Board of Trustees of the Leland Stanford Junior University Agonists of hypocretin receptor 2 for use for treating heart failure
AU2014352944A1 (en) 2013-11-20 2016-06-16 The General Hospital Corporation Methods and compositions for treating amyloid deposits
SG10201804335QA (en) 2013-11-22 2018-06-28 Univ Illinois Engineered high-affinity human t cell receptors
CA2966352A1 (en) 2013-11-26 2015-06-04 The Brigham And Women's Hospital, Inc. Compositions and methods for modulating an immune response
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
EP3083658B1 (en) 2013-12-18 2019-05-08 President and Fellows of Harvard College Crp capture/detection of gram positive bacteria
EP3083936B1 (en) 2013-12-19 2018-07-04 Danisco US Inc. Use of hydrophobins to increase gas transfer in aerobic fermentation processes
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
CN106661107B (zh) 2013-12-24 2021-12-24 杨森制药公司 抗vista抗体及片段
AU2015204840B2 (en) 2014-01-07 2020-01-30 Bioatla, Llc Proteins targeting orthologs
JP7037884B2 (ja) 2014-01-13 2022-03-17 ベイラー リサーチ インスティテュート Hpv及びhpv関連疾患に対する新規のワクチン
AU2015211034B2 (en) 2014-01-29 2020-04-09 Dana-Farber Cancer Institute, Inc. Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
WO2015120273A1 (en) 2014-02-07 2015-08-13 The General Hospital Corporation Differential diagnosis of hepatic neoplasms
US20150232935A1 (en) 2014-02-14 2015-08-20 The General Hospital Corporation Methods for diagnosing igg4-related disease
ES2818823T3 (es) 2014-02-27 2021-04-14 Biogen Ma Inc Método de evaluación del riesgo de LMP
WO2015131099A1 (en) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnosis of multiple myeloma and lymphoma
CN106231900B (zh) 2014-03-21 2019-05-28 阿吉奥斯制药公司 化合物及其使用方法
CN111077309B (zh) 2014-04-02 2023-11-17 生化诊断系统公司 利用俘获缀合物的免疫测定
ES2830849T3 (es) 2014-04-25 2021-06-04 Brigham & Womens Hospital Inc Ensayo y método para tratar sujetos con enfermedades inmunomediadas
EP2942627A1 (en) 2014-05-05 2015-11-11 MicroBPlex, Inc. Media elaborated with newly synthesized antibodies (mensa) from recently proliferated antibody secreting cells (asc) and uses thereof
US11474101B2 (en) 2014-05-08 2022-10-18 Novodiax, Inc. Direct immunohistochemistry assay
WO2015172083A1 (en) 2014-05-08 2015-11-12 Biogen Ma Inc. Dimethylfumarate and prodrugs for treatment of multiple sclerosis
WO2015175424A1 (en) 2014-05-12 2015-11-19 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
US9568404B2 (en) 2014-05-16 2017-02-14 Junyu Mai Method and apparatus for biomolecule analysis
WO2015179435A1 (en) 2014-05-19 2015-11-26 Bayer Healthcare Llc Optimized humanized monoclonal antibodies against activated protein c and uses thereof
CN107073109B (zh) 2014-06-11 2021-08-06 凯西·A·格林 Vista激动剂和拮抗剂抑制或增强体液免疫的用途
GB201413240D0 (en) 2014-07-25 2014-09-10 Hansa Medical Ab Method
CA2956925C (en) 2014-08-01 2024-02-13 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
WO2016026978A1 (en) 2014-08-22 2016-02-25 Universite Nice Sophia Antipolis Methods and pharmaceutical compositions for treating drug addiction
US20180010132A1 (en) 2014-09-11 2018-01-11 Novartis Ag Inhibition of prmt5 to treat mtap-deficiency-related diseases
EP3110447B1 (en) 2014-09-16 2020-04-29 Synermore Biologics Co., Ltd. Anti-egfr antibody and uses of same
EP3204424B1 (en) 2014-10-06 2023-11-29 ChemoCentryx, Inc. Combination therapy of c-c chemokine receptor-9 (ccr9) inhibitors and anti-alpha4beta7 integrin blocking antibodies for the treatment of inflammatory bowel disease
CN114107424A (zh) 2014-10-08 2022-03-01 诺华股份有限公司 预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
WO2016061111A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, kits & compositions for determining gene copy numbers
CN107105709B (zh) 2014-10-24 2021-04-30 杜邦营养生物科学有限公司 脯氨酸耐受性三肽基肽酶在饲料添加剂组合物中的用途
EP3172329A1 (en) 2014-10-24 2017-05-31 Danisco US Inc. Method for producing alcohol by use of a tripeptidyl peptidase
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
WO2016089920A1 (en) 2014-12-01 2016-06-09 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
WO2016089883A1 (en) 2014-12-01 2016-06-09 Novartis Ag Compositions and methods for diagnosis and treatment of prostate cancer
JP2018505911A (ja) 2014-12-05 2018-03-01 イミュネクスト,インコーポレーテッド 推定上のvista受容体としてのvsig8の同定と、vista/vsig8調節剤を産生するためのその使用
EP3230314B1 (en) 2014-12-08 2023-05-03 Berg LLC Use of markers including filamin a in the diagnosis and treatment of prostate cancer
AU2015370665B2 (en) 2014-12-23 2020-05-14 4D Pharma Research Limited Pirin polypeptide and immune modulation
KR101942955B1 (ko) 2014-12-23 2019-01-28 4디 파마 리서치 리미티드 면역 조정
JP6724023B2 (ja) 2015-02-09 2020-07-15 リサーチ ディベロップメント ファウンデーション 改善された補体活性化を示す操作された免疫グロブリンfcポリペプチド
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
SG11201706730XA (en) 2015-02-17 2017-09-28 Dovetail Genomics Llc Nucleic acid sequence assembly
WO2016138312A2 (en) 2015-02-25 2016-09-01 Vanderbilt University Antibody-mediated neutralization of marburg virus
US9974865B2 (en) 2015-03-09 2018-05-22 Agensys, Inc. Antibody drug conjugates (ADC) that bind to FLT3 proteins
US11873483B2 (en) 2015-03-11 2024-01-16 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
US11279768B1 (en) 2015-04-03 2022-03-22 Precision Biologics, Inc. Anti-cancer antibodies, combination therapies, and uses thereof
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
US10584162B2 (en) 2015-04-23 2020-03-10 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Fungal detection using mannan epitope
EP3091026B1 (en) 2015-05-08 2019-02-20 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
JP6857138B2 (ja) 2015-05-18 2021-04-14 アジェンシス,インコーポレイテッド Axlタンパク質に結合する抗体
WO2016187356A1 (en) 2015-05-18 2016-11-24 Agensys, Inc. Antibodies that bind to axl proteins
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
LT3307288T (lt) 2015-06-15 2019-10-10 4D Pharma Research Limited Kompozicijos, apimančios bakterijų kamienus
BR112017026564B1 (pt) 2015-06-15 2022-05-03 4D Pharma Research Limited Células de bactéria, usos das mesmas, e composição
JP6426265B2 (ja) 2015-06-15 2018-11-21 フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited 細菌株を含む組成物
WO2016207717A1 (en) 2015-06-24 2016-12-29 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
WO2016210395A1 (en) 2015-06-26 2016-12-29 Dupont Nutrition Biosciences Aps Aminopeptidases for protein hydrlyzates
CA2992139A1 (en) 2015-07-10 2017-01-19 West Virginia University Markers of stroke and stroke severity
WO2017015334A1 (en) 2015-07-21 2017-01-26 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
WO2017023929A1 (en) 2015-08-04 2017-02-09 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (altr) necrosis
EP3763378A1 (en) 2015-08-06 2021-01-13 President and Fellows of Harvard College Improved microbe-binding molecules and uses thereof
IL256902B2 (en) 2015-08-06 2023-10-01 Lia Diagnostics Inc Water dispersible test media
WO2017031370A1 (en) 2015-08-18 2017-02-23 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
CA2994518C (en) 2015-08-25 2025-05-06 Prothena Biosciences Limited METHODS FOR DETECTING PHOSPHORYLATED ALPHA-SYNUCLEIN
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
WO2017040813A2 (en) 2015-09-02 2017-03-09 University Of Massachusetts Detection of gene loci with crispr arrayed repeats and/or polychromatic single guide ribonucleic acids
CN116334205A (zh) 2015-09-03 2023-06-27 诺华股份有限公司 预测细胞因子释放综合征的生物标志物
EP3347464B1 (en) 2015-09-08 2024-01-24 University of Massachusetts Dnase h activity of neisseria meningitidis cas9
EP3353547A1 (en) 2015-09-22 2018-08-01 Delta TM Technologies Designing customized protein-specific buffer systems
WO2017059108A1 (en) 2015-09-29 2017-04-06 Htg Molecular Diagnostics, Inc. Methods for subtyping diffuse b-cell lymphoma (dlbcl)
WO2017062953A1 (en) 2015-10-10 2017-04-13 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3362462B1 (en) 2015-10-12 2021-07-21 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
EP3365445B1 (en) 2015-10-19 2023-05-31 Dovetail Genomics, LLC Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
US9377457B1 (en) 2015-10-19 2016-06-28 Naishu Wang Progressive compression driven flow cartridge for analyte detecting strip and method
WO2017077392A1 (en) 2015-11-06 2017-05-11 Oslo Universitetssykehus Hf Methods and devices for detecting methanol poisoning using formate oxidase
WO2017083296A1 (en) 2015-11-09 2017-05-18 The Children's Hospital Of Philadelphia Glypican 2 as a cancer marker and therapeutic target
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
PT3209310T (pt) 2015-11-20 2018-04-20 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
US11253590B2 (en) 2015-12-02 2022-02-22 Stsciences, Inc. Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator)
EP3909983A1 (en) 2015-12-02 2021-11-17 STCube & Co. Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
KR20180118105A (ko) 2015-12-04 2018-10-30 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 면역치료를 위한 slc45a2 펩티드
EP3387154A4 (en) 2015-12-09 2019-05-15 Intuitive Biosciences, Inc. AUTOMATED SILVER FINISHING SYSTEM
JOP20200228A1 (ar) 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
EP3393524B1 (en) 2015-12-22 2022-04-06 The Regents of The University of Colorado, A Body Corporate Protecting rnas from degradation using engineered viral rnas
CN109196113B (zh) 2016-02-11 2022-10-04 奇根科学有限责任公司 合成测序中的多酚添加剂
WO2017139415A2 (en) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
WO2017137830A1 (en) 2016-02-12 2017-08-17 Janssen Pharmaceutica Nv Anti-vista (b7h5) antibodies
US11112409B2 (en) 2016-02-12 2021-09-07 The Regents Of The University Of California Systems and compositions for diagnosing pathogenic fungal infection and methods of using the same
JP7366541B2 (ja) 2016-02-19 2023-10-23 コード バイオセラピューティクス インコーポレイテッド 核酸キャリア及び治療上の使用方法
WO2017147186A1 (en) 2016-02-22 2017-08-31 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
MX2018009216A (es) 2016-02-25 2018-11-09 Dupont Nutrition Biosci Aps Metodo para producir un hidrolizado de proteina empleando una tripeptidil peptidasa de aspergillus fumigatus.
CA3015839A1 (en) 2016-02-26 2017-08-31 The Board Of Regents Of The University Of Texas System Connexin (cx)43 hemichannel-binding antibodies and uses thereof
MX2018010361A (es) 2016-02-29 2019-07-08 Genentech Inc Métodos terapéuticos y de diagnóstico para el cáncer.
CN109476731A (zh) 2016-02-29 2019-03-15 基础医药有限公司 治疗癌症的方法
ES2731579T3 (es) 2016-03-04 2019-11-18 4D Pharma Plc Composiciones que comprenden cepas de blautia bacteriana para tratar hipersensibilidad visceral
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
US10458995B2 (en) 2016-03-25 2019-10-29 Muralidhar Reddy Moola Combinatorial synthesis and biomarker development
ES2883297T3 (es) 2016-03-29 2021-12-07 Stcube Inc Anticuerpos de función doble específicos para PD-L1 glucosilado y métodos de uso de los mismos
WO2017173091A1 (en) 2016-03-30 2017-10-05 Musc Foundation For Research Development Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination
US9903866B2 (en) 2016-04-05 2018-02-27 Conquerab Inc. Portable devices for detection of antibodies against therapeutic drugs
ES2866880T3 (es) 2016-04-13 2021-10-20 Inst Nat Sante Rech Med Métodos y kits para la detección rápida del clon O25B-ST131 de Escherichia Coli
WO2017181139A2 (en) 2016-04-15 2017-10-19 Michael Molloy Anti-human vista antibodies and use thereof
US9632083B1 (en) 2016-04-15 2017-04-25 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
US9702872B1 (en) 2016-04-15 2017-07-11 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
WO2017194589A1 (en) 2016-05-10 2017-11-16 Vib Vzw Inhibition of tau-mediated early synaptic dysfunction
KR102412442B1 (ko) 2016-05-13 2022-06-22 더브테일 제노믹스 엘엘씨 보존된 샘플로부터의 장범위 링키지 정보의 회수
US11919971B2 (en) 2016-05-16 2024-03-05 President And Fellows Of Harvard College Aqueous biomolecule coupling on CO2-plasma-activated surfaces
WO2017214068A1 (en) 2016-06-05 2017-12-14 Berg Llc Systems and methods for patient stratification and identification of potential biomarkers
AU2017277065A1 (en) 2016-06-06 2019-01-17 Medizinische Universität Wien Method for the detection of an IgM antibody specific for a flavivirus in a sample
CA3028682A1 (en) 2016-06-20 2017-12-28 Howard Y. Chang Circular rnas and their use in immunomodulation
US9535061B1 (en) 2016-06-29 2017-01-03 Dnt Scientific Research, Llc Multi-functional rapid diagnostic test device
WO2018013579A1 (en) 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
TWI802545B (zh) 2016-07-13 2023-05-21 英商4D製藥有限公司 包含細菌菌株之組合物
JP2019528251A (ja) 2016-07-20 2019-10-10 エスティーキューブ,インコーポレイテッド グリコシル化pd−l1に結合する抗体の組合せを使用するがんの処置および治療の方法
CA3031401A1 (en) 2016-07-20 2018-01-25 Vib Vzw Therapeutic agents for neurological and psychiatric disorders
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
CN110366558A (zh) 2016-10-28 2019-10-22 班扬生物标记公司 针对泛素c末端水解酶l1(uch-l1)和胶质纤维酸性蛋白(gfap)的抗体及相关方法
EP3534953A4 (en) 2016-11-02 2020-10-07 Vanderbilt University ANTIBODIES AGAINST HUMAN ZIKA VIRUS AND THEIR USE PROCEDURES
WO2018085679A1 (en) 2016-11-04 2018-05-11 Stave James W Direct detection of microorganisms in patient samples by immunoassay
JP7075937B2 (ja) 2016-11-09 2022-05-26 キアゲン サイエンシーズ, エルエルシー Sequencing-By-Synthesis法におけるイメージング試薬としての光防護性混合物
WO2018098353A1 (en) 2016-11-23 2018-05-31 Chemocentryx, Inc. Method of treating focal segmental glomerulosclerosis
US20180150597A1 (en) 2016-11-29 2018-05-31 Genomic Vision Sa Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
RU2019121662A (ru) 2016-12-16 2021-01-18 Мерк Патент Гмбх Способы использования галектин-3-связывающего белка, обнаруживаемого в моче, для мониторинга тяжести и прогрессирования волчаночного нефрита
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
AU2018213718B2 (en) 2017-01-26 2022-08-25 Zlip Holding Limited CD47 antigen binding unit and uses thereof
AU2018213315A1 (en) 2017-01-26 2019-07-25 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US10908168B2 (en) 2017-01-31 2021-02-02 Vanderbilt University Generation of human allergen- and helminth-specific IgE monoclonal antibodies for diagnostic and therapeutic use
WO2018163051A1 (en) 2017-03-06 2018-09-13 Novartis Ag Methods of treatment of cancer with reduced ubb expression
US11726091B2 (en) 2017-04-03 2023-08-15 The Regents Of The University Of California Compositions and methods of diagnosing pancreatic cancer
WO2018203145A1 (en) 2017-05-03 2018-11-08 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
DK3630136T3 (da) 2017-05-22 2021-05-25 4D Pharma Res Ltd Sammensætninger, der omfatter bakteriestammer
TW201907931A (zh) 2017-05-24 2019-03-01 英商4D製藥研究有限公司 包含細菌菌株之組合物
WO2018222685A1 (en) 2017-05-31 2018-12-06 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
AU2018277838C1 (en) 2017-05-31 2025-08-07 Stcube & Co., Inc. Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof
US11542331B2 (en) 2017-06-06 2023-01-03 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that bind to BTN1A1 or BTN1A1-ligands
WO2018229188A1 (en) 2017-06-14 2018-12-20 4D Pharma Research Limited Compositions comprising bacterial strains
MA49425A (fr) 2017-06-14 2020-04-22 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
IL283973B (en) 2017-06-14 2022-08-01 4D Pharma Res Ltd Compositions comprising bacterial strains
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
US9784733B1 (en) 2017-06-22 2017-10-10 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
EP4220171A3 (en) 2017-07-21 2023-10-25 Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca Markers for endometrial cancer
EP3655004A2 (en) 2017-07-21 2020-05-27 Novartis AG Compositions and methods to treat cancer
US9823244B1 (en) 2017-07-31 2017-11-21 Dnt Scientific Research, Llc Digital progressive compression driven flow cartridge for analyte detecting device and method
MA49950A (fr) 2017-08-25 2020-07-01 Five Prime Therapeutics Inc Anticorps anti-b7-h4 et leurs procédés d'utilisation
EP3626745A4 (en) 2017-09-01 2021-03-17 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. RECOMBINANT BISPECIFIC ANTIBODY
JP7365704B2 (ja) 2017-09-05 2023-10-20 グラディエーター バイオサイエンシーズ インコーポレイテッド 幹細胞へのペイロードの送達
US11464784B2 (en) 2017-09-15 2022-10-11 The Regents Of The University Of California Inhibition of aminocylase 3 (AA3) in the treatment of cancer
US20200290978A1 (en) 2017-09-26 2020-09-17 The Regents Of The University Of California Compositions and methods for treating cancer
EP3692152B1 (en) 2017-10-04 2025-09-03 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
WO2019075097A1 (en) 2017-10-11 2019-04-18 Board Of Regents, The University Of Texas System PD-L1 HUMAN ANTIBODIES AND METHODS OF USE
CA3078809A1 (en) 2017-10-11 2019-04-18 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with ccr2 antagonists
CN119930795A (zh) 2017-10-12 2025-05-06 得克萨斯大学体系董事会 用于免疫疗法的t细胞受体
EP3706795A4 (en) 2017-11-09 2021-10-13 Pinteon Therapeutics Inc. METHODS AND COMPOSITIONS FOR GENERATING AND USING HUMANIZED CONFORMATION SPECIFIC PHOSPHORYLATED TAU ANTIBODIES
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
WO2019118721A2 (en) 2017-12-15 2019-06-20 Syngenta Participations Ag Non-antibody ligands for detecting target proteins
EP3735589A2 (en) 2018-01-05 2020-11-11 Vanderbilt University Antibody-mediated neutralization of chikungunya virus
CA3090102A1 (en) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Sample prep for dna linkage recovery
WO2019155041A1 (en) 2018-02-12 2019-08-15 Vib Vzw Gβγ COMPLEX ANTIBODIES AND USES THEREOF
BR112020016986A2 (pt) 2018-02-21 2021-03-02 Five Prime Therapeutics, Inc. formulações de anticorpo contra b7-h4
WO2019165217A1 (en) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 and/or cd30 in infection
EP3759142A1 (en) 2018-03-02 2021-01-06 Five Prime Therapeutics, Inc. B7-h4 antibodies and methods of use thereof
US12339275B2 (en) 2018-03-08 2025-06-24 Meso Scale Technologies, Llc. Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury
EP3768726B1 (en) 2018-03-23 2024-10-30 Board of Regents, The University of Texas System Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
WO2019182867A1 (en) 2018-03-23 2019-09-26 Board Of Regents, The University Of Texas System Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
US11788124B2 (en) 2018-04-09 2023-10-17 Advanced Cell Diagnostics, Inc. Methods to further enhance signal amplification for the in situ detection of nucleic acids
KR20210027254A (ko) 2018-04-24 2021-03-10 앰프소스 바이오파마 상하이 인코포레이티드 Tim-3에 대한 항체 및 그의 용도
EP3788138A1 (en) 2018-05-02 2021-03-10 Novartis AG Regulators of human pluripotent stem cells and uses thereof
WO2019237119A1 (en) 2018-06-08 2019-12-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and detection methods for onchocerca volvulus infection
WO2019244107A1 (en) 2018-06-21 2019-12-26 Daiichi Sankyo Company, Limited Compositions including cd3 antigen binding fragments and uses thereof
AU2019301138B2 (en) 2018-07-11 2025-08-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (FTC, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
EP3826649A4 (en) 2018-07-23 2022-07-20 Enclear Therapies, Inc. Methods of treating neurological disorders
CA3107352A1 (en) 2018-07-23 2020-01-30 Enclear Therapies, Inc. Methods of treating neurological disorders
JP7534303B2 (ja) 2018-09-13 2024-08-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 新規のlilrb4抗体およびその使用
WO2020061591A1 (en) 2018-09-21 2020-03-26 President And Fellows Of Harvard College Methods and compositions for treating diabetes, and methods for enriching mrna coding for secreted proteins
US12258368B2 (en) 2018-09-28 2025-03-25 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
MX2021004301A (es) 2018-10-15 2021-08-05 Univ Massachusetts Edición programable de base del adn mediante proteínas de fusión nme2cas9-desaminasa.
US12510539B2 (en) 2018-10-18 2025-12-30 Progentec Diagnostics, Inc. Biomarkers for a systemic lupus erythematosus (SLE) disease activity immune index that characterizes disease activity
AU2019360758B2 (en) 2018-10-18 2024-08-08 Oklahoma Medical Research Foundation Biomarkers for a Systemic Lupus Erythematosus (SLE) disease activity immune index that characterizes disease activity
EP3872093A4 (en) 2018-10-22 2022-10-19 Shanghai Genbase Biotechnology Co., Ltd. ANTI-CLDN18.2 ANTIBODIES AND USES THEREOF
AU2019365391A1 (en) 2018-10-23 2021-04-29 Consejo Superior De Investigaciones Científicas Antibodies specific for glycosylated ApoJ and uses thereof
AU2019372675A1 (en) 2018-11-02 2021-02-04 Beijing Vdjbio Co., Ltd. Modified CTLA4 and methods of use thereof
US10451613B1 (en) 2018-11-09 2019-10-22 Dnt Scientific Research, Llc Rapid diagnostic test device and sampling method using driven flow technology
EP4657067A2 (en) 2018-11-16 2025-12-03 President And Fellows Of Harvard College Molecules and methods for improved immunodetection of small molecules, such as histamine
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
US12134657B2 (en) 2018-11-28 2024-11-05 Oregon Health & Science University Therapeutic factor XII antibody
EP4369356A3 (en) 2018-11-30 2024-07-24 Caris MPI, Inc. Next-generation molecular profiling
JP7562528B2 (ja) 2018-12-28 2024-10-07 四川科倫博泰生物医薬股▲フン▼有限公司 抗体及びその用途
CN113454238B (zh) 2019-01-25 2025-02-11 哈佛大学校长及研究员协会 用于合成核酸的组合物和方法
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
SG11202108618VA (en) 2019-02-15 2021-09-29 Advanced Cell Diagnostics Inc Methods for multiplex detection of nucleic acids by in situ hybridization
EP3938400B1 (en) 2019-03-11 2025-07-30 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
KR20220011123A (ko) 2019-04-11 2022-01-27 엔클리어 테라피스, 인크. 뇌척수액 개선 방법 및 이를 위한 디바이스 및 시스템
WO2020211674A1 (zh) 2019-04-16 2020-10-22 四川科伦博泰生物医药股份有限公司 抗FXI/FXIa抗体及其用途
CN114127312B (zh) 2019-04-30 2025-11-21 拉利玛生物医药公司 用于测定共济蛋白替代疗法的疗效的共济蛋白敏感性标志物
US11549943B2 (en) 2019-05-31 2023-01-10 International Business Machines Corporation Multiplexed lateral flow assay device
US11906515B2 (en) * 2019-05-31 2024-02-20 International Business Machines Corporation Multiplexed lateral flow assay device
WO2020245653A1 (en) 2019-06-04 2020-12-10 Alere Toxicology Plc Fluid specimen testing
DE102019117413B4 (de) * 2019-06-27 2024-05-08 Testo SE & Co. KGaA Fließtest-Einheit, Set und Verwendung einer Fließtest-Einheit zur Durchführung einer Nachweisreaktion
EP3990920B1 (en) 2019-06-27 2025-02-12 Dovetail Genomics, LLC Methods and compositions for proximity ligation
DE102019117289A1 (de) 2019-06-27 2020-12-31 Katja Werner Trägermaterial, Kitsystem und Verfahren für biologische Assays
KR20250143353A (ko) 2019-07-16 2025-10-01 메소 스케일 테크놀러지즈, 엘엘시 분석 장치, 방법, 및 시약
CN119925596A (zh) 2019-07-19 2025-05-06 费城儿童医院 包含磷脂酰肌醇蛋白聚糖2结合结构域的嵌合抗原受体
WO2021021605A1 (en) 2019-07-26 2021-02-04 Vanderbilt University Human monoclonal antibodies to enterovirus d68
WO2021055489A1 (en) 2019-09-16 2021-03-25 Grohar Patrick J Compositions and methods for the treatment of swi-snf mutant tumors
CN114401989B (zh) 2019-09-20 2024-02-09 上海吉倍生物技术有限公司 靶向bcma的抗体及嵌合抗原受体
WO2021062323A1 (en) 2019-09-26 2021-04-01 Stcube & Co. Antibodies specific to glycosylated ctla-4 and methods of use thereof
CN114206931B (zh) 2019-09-30 2024-06-04 四川科伦博泰生物医药股份有限公司 抗pd-1抗体及其用途
US20220356248A1 (en) 2019-10-09 2022-11-10 Stcube & Co Antibodies specific to glycosylated lag3 and methods of use thereof
WO2021092004A1 (en) 2019-11-05 2021-05-14 Meso Scale Technologies, Llc. Methods and kits for quantitating radiation exposure
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
US20230021837A1 (en) 2019-11-26 2023-01-26 Meso Scale Technologies, Llc. Methods and kits for detecting autoimmune diseases
EP4069865A4 (en) 2019-12-02 2023-12-20 Caris MPI, Inc. PLATINUM RESPONSE PREDICTOR IN A PAN-CANCER APPROACH
JP2023506176A (ja) 2019-12-12 2023-02-15 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 光誘導型生体分子バーコーディングのための組成物および方法
JP7749549B2 (ja) 2019-12-13 2025-10-06 シチュアン ケルン-バイオテック バイオファーマシューティカル カンパニー リミテッド 抗tslp抗体及びその使用
CN115135671B (zh) 2019-12-20 2026-01-02 新石生物制药有限公司 抗白介素-23 p19的抗体及其使用方法
EP3842452A1 (en) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Scaffold proteins and therapeutic nanoconjugates based on nidogen
CN113061165A (zh) 2020-01-02 2021-07-02 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
WO2021156490A2 (en) 2020-02-06 2021-08-12 Vib Vzw Corona virus binders
WO2021163265A1 (en) 2020-02-11 2021-08-19 Vanderbilt University Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov- 2)
WO2021167908A1 (en) 2020-02-17 2021-08-26 Board Of Regents, The University Of Texas System Methods for expansion of tumor infiltrating lymphocytes and use thereof
CN115698047A (zh) 2020-02-25 2023-02-03 非营利性组织佛兰芒综合大学生物技术研究所 富含亮氨酸的重复激酶2变构调节剂
HRP20240182T1 (hr) 2020-03-26 2024-04-26 Vanderbilt University Ljudska monoklonska protutijela za teški akutni respiratorni sindrom koronavirusa 2 (sars-cov-2)
WO2021195385A1 (en) 2020-03-26 2021-09-30 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
EP4125849A4 (en) 2020-03-31 2024-04-17 ChemoCentryx, Inc. Compositions and methods for treating inflammatory bowel disease using ccr9 inhibitor and anti-il-23 blocking antibodies
WO2021216728A1 (en) 2020-04-22 2021-10-28 President And Fellows Of Harvard College Isothermal methods, compositions, kits, and systems for detecting nucleic acids
WO2021222830A1 (en) 2020-05-01 2021-11-04 Meso Scale Technologies, Llc. Viral serology assays
WO2021228141A1 (zh) 2020-05-15 2021-11-18 四川科伦博泰生物医药股份有限公司 抗体药物缀合物及其制备方法和用途
EP3939999A1 (en) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof
EP4200440A4 (en) 2020-08-21 2024-10-09 Advanced Cell Diagnostics, Inc. COMPOSITIONS AND METHODS FOR DETERMINING T CELL CLONALITY
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
US20230331867A1 (en) 2020-09-04 2023-10-19 Novarock Biotherapeutics, Ltd. Nectin-4 antibodies and uses thereof
CA3197180A1 (en) 2020-09-29 2022-04-07 Enclear Therapies, Inc. Subarachnoid fluid management method and system
IL301950B2 (en) 2020-10-09 2025-09-01 Univ Texas Pre-stabilized hmpv f proteins
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
EP4255451A4 (en) 2020-12-03 2025-01-01 The Board Of Regents Of The University Of Texas System Methods for identifying lilrb-blocking antibodies
EP4255508A1 (en) 2020-12-04 2023-10-11 University of Tennessee Research Foundation Method for diagnosing amyloid diseases
WO2022143743A1 (zh) 2020-12-31 2022-07-07 和铂医药(苏州)有限公司 人lifr抗原结合蛋白及其制备方法和应用
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
JP2024508081A (ja) 2021-02-09 2024-02-22 メディリンク セラピューティクス(スーチョウ)カンパニー,リミティド 生物活性物質コンジュゲート、その調製方法及びその使用
IL305318A (en) 2021-02-19 2023-10-01 Vib Vzw Cation-independent mannose-6-phosphate receptor binders
US20240150455A1 (en) 2021-03-05 2024-05-09 Shanghai GenBase Biotechnology Co., Ltd. Anti-cldn6 antibody and use thereof
CN117729942A (zh) 2021-03-08 2024-03-19 伊缪诺金公司 用于增加靶向adam9的免疫缀合物治疗癌症的功效的方法
EP4306540A4 (en) 2021-03-09 2025-05-28 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. ROR1-BINDING PROTEIN AND USE THEREOF
EP4320443A1 (en) 2021-04-06 2024-02-14 BPGbio, Inc. Protein markers for the prognosis of breast cancer progression
US20230059578A1 (en) 2021-04-06 2023-02-23 Berg Llc Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
US20240402177A1 (en) 2021-04-06 2024-12-05 Bpgbio, Inc. Protein markers for estrogen receptor (er)-positive luminal a (la)-like and luminal b1 (lb1)-like breast cancer
WO2022221635A1 (en) 2021-04-16 2022-10-20 Advanced Cell Diagnostics, Inc. Materials and methods related to image processing
JP2024515726A (ja) 2021-04-19 2024-04-10 テンプル セラピューティクス ビーブイ 子宮内膜過剰増殖性障害および卵巣過剰増殖性障害を検出または処置するための方法
WO2022246215A1 (en) 2021-05-21 2022-11-24 Meso Scale Technologies, Llc. Viral strain serology assays
WO2023288046A1 (en) 2021-07-15 2023-01-19 President And Fellows Of Harvard College Compositions and methods relating to cells with adhered particles
CN118556133A (zh) 2021-07-23 2024-08-27 瓦尔德西布伦大学医院基金会研究所 子宫内膜癌的生物标记物
CA3228014A1 (en) 2021-07-30 2023-02-16 Vib Vzm Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
CA3236778A1 (en) 2021-11-02 2023-05-11 Erik SONTHEIMER Nme2cas9 inlaid domain fusion proteins
EP4433507A2 (en) 2021-11-19 2024-09-25 MiroBio Limited Pd-1 antibodies and uses thereof
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
JP2025503322A (ja) 2022-01-25 2025-01-30 メディリンク セラピューティクス (スージョウ) カンパニー リミテッド Her3に対する抗体、複合体、及びその使用
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
EP4238988A1 (en) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Antibodies against sars-cov-2 and uses thereof
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
IL316011A (en) 2022-04-01 2024-11-01 Univ Texas Dual specific antibodies to human PD-L1 and PD-L2 and methods of using them
KR20240169114A (ko) 2022-04-06 2024-12-02 라리마 테라퓨틱스, 인코포레이티드 프라탁신 대체 요법 모니터링을 위한 프라탁신 민감성 마커
AU2023251091A1 (en) 2022-04-06 2024-10-10 Gilead Sciences, Inc. Engineered cd200r antibodies and uses thereof
JP2025519540A (ja) 2022-06-08 2025-06-26 オンキュアー,インコーポレイテッド Pi3k阻害剤としてのベンゾピリミジン-4(3h)-オン
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
WO2023239940A1 (en) 2022-06-10 2023-12-14 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof
EP4540610A1 (en) 2022-06-17 2025-04-23 Meso Scale Technologies, LLC Viral strain serology assays
KR20250028265A (ko) 2022-06-20 2025-02-28 쓰추안 휘위 파머슈티컬 컴퍼니., 리미티드. 항체 및 이의 용도
WO2024012523A1 (zh) 2022-07-14 2024-01-18 苏州宜联生物医药有限公司 抗体药物偶联物及其制备方法和用途
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
EP4573553A1 (en) 2022-08-15 2025-06-25 ABSCI Corporation Quantitative affinity activity specific cell enrichment
WO2024038160A1 (en) 2022-08-18 2024-02-22 Vib Vzw Means and methods to modulate neuron excitability
CN120265619A (zh) 2022-09-08 2025-07-04 恩库勒公司 作为pi3k抑制剂的异喹诺酮
WO2024064024A1 (en) 2022-09-19 2024-03-28 Onkure, Inc. ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer
EP4590317A1 (en) 2022-09-20 2025-07-30 OnKure, Inc. Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation
WO2024064904A1 (en) 2022-09-23 2024-03-28 Meso Scale Technologies, Llc. Orthopoxvirus serology assays
EP4594348A1 (en) 2022-09-27 2025-08-06 Vib Vzw Antivirals against human parainfluenza virus
WO2024081345A1 (en) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones as pi3k inhibitors
JP2025537294A (ja) 2022-11-11 2025-11-14 アイジーエーエヌ バイオサイエンシーズ IgAプロテアーゼポリペプチド剤
WO2024124041A1 (en) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Multiplexed detection of nucleic acid targets
CN120569211A (zh) 2023-01-09 2025-08-29 得克萨斯州大学系统董事会 融合前稳定的人副流感病毒3f蛋白
KR20250155004A (ko) 2023-02-23 2025-10-29 유니버시티 오브 로체스터 폐쇄 말단 dna 가닥 분자를 제조하기 위한 제제 및 방법
WO2024213648A1 (en) 2023-04-11 2024-10-17 Sterling Ip Pte. Ltd. Treatment of haematological cancer
WO2024258743A1 (en) 2023-06-13 2024-12-19 Adcentrx Therapeutics, Inc. Methods and compositions related to antibodies and antibody drug conjugates (adcs) that bind nectin-4 proteins
WO2024261344A1 (en) 2023-06-23 2024-12-26 Vib Vzw Novel binders targeting the multi-drug resistant pathogen acinetobacter baumannii
WO2025038395A1 (en) 2023-08-11 2025-02-20 Onkure, Inc. Benzopyridinones and benzopyrimidinones as pi3k inhibitors
WO2025049305A1 (en) 2023-08-25 2025-03-06 Meso Scale Technologies, Llc. Viral strain serology assays
WO2025054524A1 (en) 2023-09-07 2025-03-13 University Of Tennessee Research Foundation Method for diagnosing amyloid diseases
WO2025125577A1 (en) 2023-12-14 2025-06-19 Vib Vzw Antibodies against influenza b virus
WO2025155991A2 (en) 2024-01-19 2025-07-24 Bpgbio, Inc. Predictive biomarkers for response to coenzyme q10 treatment in pancreatic cancer
WO2025202871A1 (en) 2024-03-27 2025-10-02 Pfizer Inc. Methods for identifying biomarkers of treatment response and use thereof with a cdk4 inhibitor
WO2025207755A1 (en) 2024-03-29 2025-10-02 Onkure, Inc. Quinolizinones as pi3k inhibitors
WO2025212360A1 (en) 2024-04-01 2025-10-09 Onkure, Inc. Isoquinolones as pi3k inhibitors
WO2025255233A1 (en) 2024-06-07 2025-12-11 Onkure, Inc. Compounds containing fused tricyclic rings as pi3k inhibitors
WO2025264533A1 (en) 2024-06-17 2025-12-26 Adcentrx Therapeutics Inc. Methods and compositions related to antibody drug conjugates (adcs) that bind steap-1 proteins
WO2026006151A2 (en) 2024-06-24 2026-01-02 University Of Rochester Functionalization of ace-trna encoding synthetic linear picovectors
WO2026008664A1 (en) 2024-07-01 2026-01-08 Vib Vzw Allosteric modulators of inhibitory immune receptor complexes

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3811840A (en) * 1969-04-01 1974-05-21 Miles Lab Test device for detecting low concentrations of substances in fluids
US4190496A (en) * 1971-05-14 1980-02-26 Syva Company Homogeneous enzyme assay for antibodies
CA983358A (en) * 1971-09-08 1976-02-10 Kenneth D. Bagshawe Performance of chemical or biological reactions
JPS4939720A (en:Method) * 1972-08-26 1974-04-13
DE2436598C2 (de) * 1974-07-30 1983-04-07 Boehringer Mannheim Gmbh, 6800 Mannheim Stabiler Teststreifen zum Nachweis von Inhaltsstoffen in Flüssigkeiten
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
CA1095819A (en) * 1977-01-14 1981-02-17 Eastman Kodak Company Element for analysis of liquids
IL51354A (en) * 1977-01-28 1979-07-25 Ames Yissum Ltd Assay method for the quantitative determination of a hapten in aqueous solution
US4160008A (en) * 1978-01-26 1979-07-03 Miles Laboratories, Inc. Multilayered test device for determining the presence of a liquid sample component, and method of use
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays

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EP0046004A1 (en) 1982-02-17
EP0046004B1 (en) 1984-11-28
JPS5763454A (en) 1982-04-16
MY8700300A (en) 1987-12-31
CA1174595A (en) 1984-09-18
HK15887A (en) 1987-02-27
JP2505979B2 (ja) 1996-06-12
JPH06317596A (ja) 1994-11-15
JPH0654317B2 (ja) 1994-07-20
JPH03142361A (ja) 1991-06-18
US4366241B1 (en:Method) 1988-10-18
JPH0322589B2 (en:Method) 1991-03-27
DE3167436D1 (en) 1985-01-10
US4366241A (en) 1982-12-28
SG89186G (en) 1987-03-27

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