DK2828284T3 - Jcv-neutraliserende antistoffer - Google Patents

Jcv-neutraliserende antistoffer Download PDF

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Publication number
DK2828284T3
DK2828284T3 DK13765090.9T DK13765090T DK2828284T3 DK 2828284 T3 DK2828284 T3 DK 2828284T3 DK 13765090 T DK13765090 T DK 13765090T DK 2828284 T3 DK2828284 T3 DK 2828284T3
Authority
DK
Denmark
Prior art keywords
neutralizing antibodies
jcv neutralizing
jcv
antibodies
neutralizing
Prior art date
Application number
DK13765090.9T
Other languages
English (en)
Inventor
Kenneth Simon
Thomas Cameron
Deping Wang
Joseph Arndt
Mia Rushe
Justin Caravella
Eric Day
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Application granted granted Critical
Publication of DK2828284T3 publication Critical patent/DK2828284T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK13765090.9T 2012-03-20 2013-03-15 Jcv-neutraliserende antistoffer DK2828284T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261613214P 2012-03-20 2012-03-20
PCT/US2013/031842 WO2013142299A1 (en) 2012-03-20 2013-03-15 Jcv neutralizing antibodies

Publications (1)

Publication Number Publication Date
DK2828284T3 true DK2828284T3 (da) 2019-06-11

Family

ID=49223243

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13765090.9T DK2828284T3 (da) 2012-03-20 2013-03-15 Jcv-neutraliserende antistoffer

Country Status (15)

Country Link
US (1) US9567392B2 (da)
EP (2) EP2828284B1 (da)
CA (1) CA2867902C (da)
CY (1) CY1121856T1 (da)
DK (1) DK2828284T3 (da)
ES (1) ES2731757T3 (da)
HR (1) HRP20190937T1 (da)
HU (1) HUE044838T2 (da)
LT (1) LT2828284T (da)
PL (1) PL2828284T3 (da)
PT (1) PT2828284T (da)
RS (1) RS58910B1 (da)
SI (1) SI2828284T1 (da)
TR (1) TR201909801T4 (da)
WO (1) WO2013142299A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9567391B2 (en) 2012-03-20 2017-02-14 Biogen Ma Inc. JCV neutralizing antibodies
CA2867902C (en) 2012-03-20 2023-09-26 Biogen Idec Ma Inc. Jcv neutralizing antibodies
ITTO20120570A1 (it) * 2012-06-27 2013-12-28 Pomona Ricerca Srl Anticorpo monoclonale diretto contro il virus jc
US9862760B2 (en) 2015-09-16 2018-01-09 Novartis Ag Polyomavirus neutralizing antibodies
WO2019106578A2 (en) 2017-12-01 2019-06-06 Novartis Ag Polyomavirus neutralizing antibodies
CA3142000A1 (en) * 2019-06-19 2020-12-24 Icahn School Of Medicine At Mount Sinai Monoclonal antibodies against jc virus

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US4472509A (en) 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
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GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
DK0590058T3 (da) 1991-06-14 2004-03-29 Genentech Inc Humaniseret heregulin-antistof
DK0678122T3 (da) 1993-01-12 2000-03-06 Biogen Inc Rekombinante anti-VLA4 antistofmolekyler
ES2114183T5 (es) 1993-02-09 2006-06-16 Biogen Idec Ma, Inc. Anticuerpo para el tratamiento de la diabetes dependiente de la insulina.
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WO2008118013A2 (en) * 2007-03-23 2008-10-02 To-Bbb Holding B.V. Targeted intracellular delivery of antiviral agents
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BRPI0914319B8 (pt) * 2008-06-25 2021-05-25 Esbatech Alcon Biomed Res Unit imunoligante que se liga especificamente ao tnf alfa humano e composição
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US9567391B2 (en) 2012-03-20 2017-02-14 Biogen Ma Inc. JCV neutralizing antibodies

Also Published As

Publication number Publication date
PL2828284T3 (pl) 2019-11-29
SI2828284T1 (sl) 2019-10-30
EP2828284A4 (en) 2015-07-22
TR201909801T4 (tr) 2019-07-22
CA2867902C (en) 2023-09-26
EP2828284A1 (en) 2015-01-28
CA2867902A1 (en) 2013-09-26
HRP20190937T1 (hr) 2019-10-04
PT2828284T (pt) 2019-06-17
EP2828284B1 (en) 2019-05-08
US20150050271A1 (en) 2015-02-19
WO2013142299A1 (en) 2013-09-26
CY1121856T1 (el) 2020-07-31
US9567392B2 (en) 2017-02-14
RS58910B1 (sr) 2019-08-30
HUE044838T2 (hu) 2019-11-28
EP3575311A1 (en) 2019-12-04
LT2828284T (lt) 2019-08-26
ES2731757T3 (es) 2019-11-18

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