US20130291227A1 - Pesticidal compositions and processes related thereto - Google Patents
Pesticidal compositions and processes related thereto Download PDFInfo
- Publication number
- US20130291227A1 US20130291227A1 US13/788,736 US201313788736A US2013291227A1 US 20130291227 A1 US20130291227 A1 US 20130291227A1 US 201313788736 A US201313788736 A US 201313788736A US 2013291227 A1 US2013291227 A1 US 2013291227A1
- Authority
- US
- United States
- Prior art keywords
- substituted
- unsubstituted
- methyl
- sodium
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 *N([6*])C(=[7*])[8*] Chemical compound *N([6*])C(=[7*])[8*] 0.000 description 58
- DBHVHTPMRCXCIY-UHFFFAOYSA-N CCN(C(=O)CCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl DBHVHTPMRCXCIY-UHFFFAOYSA-N 0.000 description 3
- MXERTNXQEMIYGL-UHFFFAOYSA-N NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound NC1=CN(C2=CC=CN=C2)N=C1Cl MXERTNXQEMIYGL-UHFFFAOYSA-N 0.000 description 3
- XYYIMXIPUHZKKQ-UHFFFAOYSA-N C=CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl XYYIMXIPUHZKKQ-UHFFFAOYSA-N 0.000 description 2
- QDYZIPQEBLXKAS-UHFFFAOYSA-N CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 QDYZIPQEBLXKAS-UHFFFAOYSA-N 0.000 description 2
- LXCUMNGYEONUDK-UHFFFAOYSA-N CC1=NN(C2=CC=CN=C2)C=C1I Chemical compound CC1=NN(C2=CC=CN=C2)C=C1I LXCUMNGYEONUDK-UHFFFAOYSA-N 0.000 description 2
- QYMMXFXDUHOULF-UHFFFAOYSA-N CCN(C(=O)C(C)C(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)C(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl QYMMXFXDUHOULF-UHFFFAOYSA-N 0.000 description 2
- UGTOCQAYPYIOGU-UHFFFAOYSA-N CCN(C(=O)C(C)O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)O)C1=CN(C2=CC=CN=C2)N=C1Cl UGTOCQAYPYIOGU-UHFFFAOYSA-N 0.000 description 2
- FDYHWUWOIVJVKI-UHFFFAOYSA-N CCN(C(=O)C(C)SCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)SCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl FDYHWUWOIVJVKI-UHFFFAOYSA-N 0.000 description 2
- NEHPGVVQAXMXRI-UHFFFAOYSA-N CCN(C(=O)CC(SCC1CC1(F)F)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CC(SCC1CC1(F)F)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl NEHPGVVQAXMXRI-UHFFFAOYSA-N 0.000 description 2
- YASWYUIBRVSWJM-UHFFFAOYSA-N CCN(C(=O)CCS(=O)(=O)CC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(=O)(=O)CC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YASWYUIBRVSWJM-UHFFFAOYSA-N 0.000 description 2
- BUTXJHNFXHLCIM-UHFFFAOYSA-N CCN(C(=O)CCS(=O)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(=O)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl BUTXJHNFXHLCIM-UHFFFAOYSA-N 0.000 description 2
- VCJUTFKMGSOWDA-UHFFFAOYSA-N CCN(C(=O)CCSCCC(C)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCCC(C)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl VCJUTFKMGSOWDA-UHFFFAOYSA-N 0.000 description 2
- IOSNVLMQSHMZKZ-UHFFFAOYSA-N CCN(C(=O)CCl)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCl)C1=CN(C2=CC=CN=C2)N=C1Cl IOSNVLMQSHMZKZ-UHFFFAOYSA-N 0.000 description 2
- NTGYACNCQLGPDG-UHFFFAOYSA-N CNC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl Chemical compound CNC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl NTGYACNCQLGPDG-UHFFFAOYSA-N 0.000 description 2
- SLNACYWQHGJYMR-UHFFFAOYSA-N COC(CCC(O)CCC(F)(F)F)OC Chemical compound COC(CCC(O)CCC(F)(F)F)OC SLNACYWQHGJYMR-UHFFFAOYSA-N 0.000 description 2
- VMRVPRGUIUBZCF-UHFFFAOYSA-N COC1=CC=CC(C(CC(=O)O)SC)=C1 Chemical compound COC1=CC=CC(C(CC(=O)O)SC)=C1 VMRVPRGUIUBZCF-UHFFFAOYSA-N 0.000 description 2
- YCSPJSUYGGCVFK-UHFFFAOYSA-N CSC(CC(=O)O)C(F)(F)F Chemical compound CSC(CC(=O)O)C(F)(F)F YCSPJSUYGGCVFK-UHFFFAOYSA-N 0.000 description 2
- MNAVTBJIELHFMV-UHFFFAOYSA-N CSC(CC(=O)O)C1=CC=C(C(F)(F)F)C=C1 Chemical compound CSC(CC(=O)O)C1=CC=C(C(F)(F)F)C=C1 MNAVTBJIELHFMV-UHFFFAOYSA-N 0.000 description 2
- TUXTXCFNJKHYSA-UHFFFAOYSA-N O=C(O)CCC(=O)CCC(F)(F)F Chemical compound O=C(O)CCC(=O)CCC(F)(F)F TUXTXCFNJKHYSA-UHFFFAOYSA-N 0.000 description 2
- CSYWOKSVHVKGJP-UHFFFAOYSA-N [H]N(CC)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound [H]N(CC)C1=CN(C2=CC=CN=C2)N=C1 CSYWOKSVHVKGJP-UHFFFAOYSA-N 0.000 description 2
- UVHHIYCQINOSKJ-UHFFFAOYSA-N [H]N(CCC)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound [H]N(CCC)C1=CN(C2=CC=CN=C2)N=C1 UVHHIYCQINOSKJ-UHFFFAOYSA-N 0.000 description 2
- KBYVMELTSIXQTA-UHFFFAOYSA-N Br.CSCCC(=N)SCC1=CC2=C(C=CC=C2)C=C1 Chemical compound Br.CSCCC(=N)SCC1=CC2=C(C=CC=C2)C=C1 KBYVMELTSIXQTA-UHFFFAOYSA-N 0.000 description 1
- AEQPCNLUSNRCHM-UHFFFAOYSA-N Br.NC1=C(Br)NN=C1 Chemical compound Br.NC1=C(Br)NN=C1 AEQPCNLUSNRCHM-UHFFFAOYSA-N 0.000 description 1
- XTNWYKHPYRLHTI-UHFFFAOYSA-N C#CCN(C(=O)C(C)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C#CCN(C(=O)C(C)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl XTNWYKHPYRLHTI-UHFFFAOYSA-N 0.000 description 1
- SVPRDBWYSRQEDP-UHFFFAOYSA-N C#CCN(C(=O)C(C)S(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C#CCN(C(=O)C(C)S(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl SVPRDBWYSRQEDP-UHFFFAOYSA-N 0.000 description 1
- HVYOYHAFUWLFLT-UHFFFAOYSA-N C#CCN(C(=O)C(C)SC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C#CCN(C(=O)C(C)SC)C1=CN(C2=CC=CN=C2)N=C1Cl HVYOYHAFUWLFLT-UHFFFAOYSA-N 0.000 description 1
- BQOAGCQMMGGEKO-UHFFFAOYSA-N C#CCN(C(=O)CC(C)SC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C#CCN(C(=O)CC(C)SC)C1=CN(C2=CC=CN=C2)N=C1Cl BQOAGCQMMGGEKO-UHFFFAOYSA-N 0.000 description 1
- RVWWDFXUPHSUQS-UHFFFAOYSA-N C#CCN(C(=O)CCSC)C1=CN(C2=CC(F)=CN=C2)N=C1C Chemical compound C#CCN(C(=O)CCSC)C1=CN(C2=CC(F)=CN=C2)N=C1C RVWWDFXUPHSUQS-UHFFFAOYSA-N 0.000 description 1
- YAJKAAMPAXOGNK-UHFFFAOYSA-N C#CCN(C(=O)OC(C)(C)C)C1=CN(C2=CC(F)=CN=C2)N=C1C Chemical compound C#CCN(C(=O)OC(C)(C)C)C1=CN(C2=CC(F)=CN=C2)N=C1C YAJKAAMPAXOGNK-UHFFFAOYSA-N 0.000 description 1
- ZVKRPEXGIYVIMT-UHFFFAOYSA-N C#CCNC1=CN(C2=CC(F)=CN=C2)N=C1C.Cl Chemical compound C#CCNC1=CN(C2=CC(F)=CN=C2)N=C1C.Cl ZVKRPEXGIYVIMT-UHFFFAOYSA-N 0.000 description 1
- LFBTXRWBPQUMCW-UHFFFAOYSA-N C#CCNC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C#CCNC1=CN(C2=CC=CN=C2)N=C1Cl LFBTXRWBPQUMCW-UHFFFAOYSA-N 0.000 description 1
- XYUBACKJTGHJJR-YWXSNLATSA-N C.C.CC(C)(C)OC(=O)N(CCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC/N=C(\SCC)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CS)C1=CN(C2=CC=CN=C2)N=C1Cl.CS(=O)(=O)N[C@@H]1C=C[C@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1.CS(=O)(=O)N[C@H]1C=C[C@@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1 Chemical compound C.C.CC(C)(C)OC(=O)N(CCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC/N=C(\SCC)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CS)C1=CN(C2=CC=CN=C2)N=C1Cl.CS(=O)(=O)N[C@@H]1C=C[C@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1.CS(=O)(=O)N[C@H]1C=C[C@@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1 XYUBACKJTGHJJR-YWXSNLATSA-N 0.000 description 1
- CCHYJYWUCKOOMY-UHFFFAOYSA-N C.C.CC(C)C(=O)N(C)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.CC(C)C(=O)NC1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CC1=CN=CC(N2C=C(N(C)C(=O)C(C)C)C(Cl)=N2)=C1.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.COC1=CN=CC(N2C=C(N(C)C(=O)C(C)C)C(Cl)=N2)=C1.COC1=CN=CC(N2C=C(NC(=O)CCC(F)(F)F)C(Cl)=N2)=C1 Chemical compound C.C.CC(C)C(=O)N(C)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.CC(C)C(=O)NC1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CC1=CN=CC(N2C=C(N(C)C(=O)C(C)C)C(Cl)=N2)=C1.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.COC1=CN=CC(N2C=C(N(C)C(=O)C(C)C)C(Cl)=N2)=C1.COC1=CN=CC(N2C=C(NC(=O)CCC(F)(F)F)C(Cl)=N2)=C1 CCHYJYWUCKOOMY-UHFFFAOYSA-N 0.000 description 1
- NJTXZWOHITWCEO-NDFTZUQLSA-N C.C/N=C(\C)NC1=CN(C2=CC=CN=C2)N=C1Cl.CC(O)CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)OS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C(F)(F)Br)C1=CN(C2=CC=CN=C2)N=C1Cl.[H]/N=C(\C)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C.C/N=C(\C)NC1=CN(C2=CC=CN=C2)N=C1Cl.CC(O)CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)OS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C(F)(F)Br)C1=CN(C2=CC=CN=C2)N=C1Cl.[H]/N=C(\C)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl NJTXZWOHITWCEO-NDFTZUQLSA-N 0.000 description 1
- COGWYBMDMGCRJZ-HLDJWKBUSA-N C.CC1=NN(C2=CC=CN=C2)C(F)=C1N(CC1=CC=CC=C1)C(=O)OC(C)(C)C.CC1=NNC(C)=C1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN1N=CC(C(=O)N(C)C2=CN(C3=CC=CN=C3)N=C2Cl)=C1C.CN(C(=O)CC1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN1N=C(C(F)(F)F)C=C1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C.CC1=NN(C2=CC=CN=C2)C(F)=C1N(CC1=CC=CC=C1)C(=O)OC(C)(C)C.CC1=NNC(C)=C1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN1N=CC(C(=O)N(C)C2=CN(C3=CC=CN=C3)N=C2Cl)=C1C.CN(C(=O)CC1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN1N=C(C(F)(F)F)C=C1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl COGWYBMDMGCRJZ-HLDJWKBUSA-N 0.000 description 1
- WXJGETBRAPVOHD-CGVXWGMTSA-N C.CCN(C(=O)CCS(C)(=O)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1=CC=C(Cl)S1.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1CC1.CS(=O)(=O)N[C@@H]1CC[C@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1 Chemical compound C.CCN(C(=O)CCS(C)(=O)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1=CC=C(Cl)S1.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1CC1.CS(=O)(=O)N[C@@H]1CC[C@H](C(=O)NC2=CN(C3=CC=CN=C3)N=C2Cl)C1 WXJGETBRAPVOHD-CGVXWGMTSA-N 0.000 description 1
- YJLYGWOUDNVDMM-UHFFFAOYSA-N C1=CN=CC(N2C=CC=N2)=C1 Chemical compound C1=CN=CC(N2C=CC=N2)=C1 YJLYGWOUDNVDMM-UHFFFAOYSA-N 0.000 description 1
- RMHXFFLGUMWQSX-UHFFFAOYSA-N C1CSC1.C=S1(=O)CCC1.CC.CC.CC.O=S1CCC1 Chemical compound C1CSC1.C=S1(=O)CCC1.CC.CC.CC.O=S1CCC1 RMHXFFLGUMWQSX-UHFFFAOYSA-N 0.000 description 1
- PWWOFFUSWXUJKT-UHFFFAOYSA-N C=C(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CS(C)(=O)=NC#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CS(C)(=O)=NC#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)/S(C)=N/C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)S(C)(=O)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=C(SC(F)(F)F)C=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC=CC=N1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=C(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CS(C)(=O)=NC#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CS(C)(=O)=NC#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)/S(C)=N/C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)S(C)(=O)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=C(SC(F)(F)F)C=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC=CC=N1)C1=CN(C2=CC=CN=C2)N=C1Cl PWWOFFUSWXUJKT-UHFFFAOYSA-N 0.000 description 1
- IPZPRFJPNDBPEK-UHFFFAOYSA-N C=C1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O Chemical compound C=C1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O IPZPRFJPNDBPEK-UHFFFAOYSA-N 0.000 description 1
- RJFAESASIUSDIY-UHFFFAOYSA-N C=C1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O.CC#CCN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(CCCCl)NC1=CN(C2=CC=CN=C2)N=C1Cl.O=C1CCCN1C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=C1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O.CC#CCN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(CCCCl)NC1=CN(C2=CC=CN=C2)N=C1Cl.O=C1CCCN1C1=CN(C2=CC=CN=C2)N=C1Cl RJFAESASIUSDIY-UHFFFAOYSA-N 0.000 description 1
- JWCYAZMVXBIIGH-UHFFFAOYSA-N C=CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C/S(C)=N/C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS(C)(=O)=NC(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C/S(C)=N/C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS(C)(=O)=NC(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl JWCYAZMVXBIIGH-UHFFFAOYSA-N 0.000 description 1
- AFFQDYFYLHSEGP-UHFFFAOYSA-N C=CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)C(=O)N(C)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CC1=CN=CC(N2C=C(N(C)C(=O)CCC(F)(F)F)C(Cl)=N2)=C1.CCN(C(=O)C1C(C=C(Cl)Cl)C1(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.O=C(CCS)NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)C(=O)N(C)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.CC1=CN=CC(N2C=C(N(C)C(=O)CCC(F)(F)F)C(Cl)=N2)=C1.CCN(C(=O)C1C(C=C(Cl)Cl)C1(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCC(F)(F)F)C1=CN(C2=CC(Br)=CN=C2)N=C1Cl.O=C(CCS)NC1=CN(C2=CC=CN=C2)N=C1Cl AFFQDYFYLHSEGP-UHFFFAOYSA-N 0.000 description 1
- PBYIHDBXTYDYEP-UHFFFAOYSA-N C=CCCO[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C(C)(C)C.CC(C)(C)[Si](OCCC1CC1(F)F)(C1=CC=CC=C1)C1=CC=CC=C1.CC1=CC=C(S(=O)(=O)OCCC2CC2(F)F)C=C1.OCCC1CC1(F)F Chemical compound C=CCCO[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C(C)(C)C.CC(C)(C)[Si](OCCC1CC1(F)F)(C1=CC=CC=C1)C1=CC=CC=C1.CC1=CC=C(S(=O)(=O)OCCC2CC2(F)F)C=C1.OCCC1CC1(F)F PBYIHDBXTYDYEP-UHFFFAOYSA-N 0.000 description 1
- URPABJYGQZXDQD-UHFFFAOYSA-N C=CCNC1=CN(C2=CC(F)=CN=C2)N=C1C.Cl Chemical compound C=CCNC1=CN(C2=CC(F)=CN=C2)N=C1C.Cl URPABJYGQZXDQD-UHFFFAOYSA-N 0.000 description 1
- PDNYSXBQBJXJHZ-UHFFFAOYSA-N C=CS(=O)CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=CS(=O)CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl PDNYSXBQBJXJHZ-UHFFFAOYSA-N 0.000 description 1
- HQPJCMSFROMNCL-UHFFFAOYSA-N C=CSC(C)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound C=CSC(C)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl HQPJCMSFROMNCL-UHFFFAOYSA-N 0.000 description 1
- KWRXXMHBWQXZAR-UHFFFAOYSA-N CC(=O)C=C1CCC1 Chemical compound CC(=O)C=C1CCC1 KWRXXMHBWQXZAR-UHFFFAOYSA-N 0.000 description 1
- IJBTZOKIUHTFOR-UHFFFAOYSA-N CC(=O)CCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=S)N1CCOC1=O.CC1=NN(C2=CC=CN=C2)C=C1NC(=S)N1CCOC1=O.CCN(C(=O)SC(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCC(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CSC(NC1=CN(C2=CC=CN=C2)N=C1C)N1CCOC1=O Chemical compound CC(=O)CCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=S)N1CCOC1=O.CC1=NN(C2=CC=CN=C2)C=C1NC(=S)N1CCOC1=O.CCN(C(=O)SC(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCC(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CSC(NC1=CN(C2=CC=CN=C2)N=C1C)N1CCOC1=O IJBTZOKIUHTFOR-UHFFFAOYSA-N 0.000 description 1
- QIFQOVKQXIAUKZ-UHFFFAOYSA-N CC(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl QIFQOVKQXIAUKZ-UHFFFAOYSA-N 0.000 description 1
- BWWVVDBHOKBNEC-UHFFFAOYSA-N CC(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)C(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1=NN(C2=CC(F)=CN=C2)C(F)=C1N(C)C(=O)OC(C)(C)C.CCN(C(=O)C1=CC(C(C)(C)C)=NN1C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1Cl Chemical compound CC(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)C(=O)N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1=NN(C2=CC(F)=CN=C2)C(F)=C1N(C)C(=O)OC(C)(C)C.CCN(C(=O)C1=CC(C(C)(C)C)=NN1C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CCOCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1Cl BWWVVDBHOKBNEC-UHFFFAOYSA-N 0.000 description 1
- XCHDHDPNZLMOFY-UHFFFAOYSA-N CC(=O)N(CC1=CC=CC=C1)C1=CN(C2=CC(F)=CN=C2)N=C1C.CC(=S)N(CC1=CC=CC=C1)C1=CN(C2=CC(F)=CN=C2)N=C1C.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C(=O)C(C)(C)C.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1=CC=CC=C1.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(C)(=O)=O.CCOC(=O)N(CC)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(=O)N(CC1=CC=CC=C1)C1=CN(C2=CC(F)=CN=C2)N=C1C.CC(=S)N(CC1=CC=CC=C1)C1=CN(C2=CC(F)=CN=C2)N=C1C.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C(=O)C(C)(C)C.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(=O)(=O)C1=CC=CC=C1.CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(C)(=O)=O.CCOC(=O)N(CC)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl XCHDHDPNZLMOFY-UHFFFAOYSA-N 0.000 description 1
- GHGFTFVJVIMRCO-UHFFFAOYSA-N CC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C.CCC(Cl)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(Cl)CC(F)(F)F)C1=CN(C2=CC=CN=C2)C=C1Cl.CCN(C(=O)C1=CC=C(Cl)C=C1)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC/S(C)=N\C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC)C1=C(SC)N(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C.CCC(Cl)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(Cl)CC(F)(F)F)C1=CN(C2=CC=CN=C2)C=C1Cl.CCN(C(=O)C1=CC=C(Cl)C=C1)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC/S(C)=N\C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC)C1=C(SC)N(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC)C1=CN(C2=CC=CN=C2)N=C1Cl GHGFTFVJVIMRCO-UHFFFAOYSA-N 0.000 description 1
- BDUXNQXCEPEZEL-UHFFFAOYSA-N CC(=O)OCCN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CC1CO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS(=O)(CCC(F)(F)F)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C1OC(CO)CN1C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(=O)OCCN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CC1CO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCS(=O)(CCC(F)(F)F)=NC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C1OC(CO)CN1C1=CN(C2=CC=CN=C2)N=C1Cl BDUXNQXCEPEZEL-UHFFFAOYSA-N 0.000 description 1
- CALGIEBSJLYYOS-UHFFFAOYSA-N CC(=O)SCC(C(=O)O)C(F)(F)F Chemical compound CC(=O)SCC(C(=O)O)C(F)(F)F CALGIEBSJLYYOS-UHFFFAOYSA-N 0.000 description 1
- PXDLMTBSHBELFS-UHFFFAOYSA-N CC(C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(Cl)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CC#N)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(Cl)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)C#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CC#N)C1=CN(C2=CC=CN=C2)N=C1Cl PXDLMTBSHBELFS-UHFFFAOYSA-N 0.000 description 1
- WHMSWJPVAYIVEG-MHYRVXTHSA-N CC(C#N)C(=O)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC1=CC=CO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl.CSC(F)(F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C#N)C(=O)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC1=CC=CO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl.CSC(F)(F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl WHMSWJPVAYIVEG-MHYRVXTHSA-N 0.000 description 1
- GVSXJPDCWSETFG-UHFFFAOYSA-N CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=C(Cl)N(C2=CC=CN=C2)N=C1 Chemical compound CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=C(Cl)N(C2=CC=CN=C2)N=C1 GVSXJPDCWSETFG-UHFFFAOYSA-N 0.000 description 1
- DDSKAVRLRVBOSA-UHFFFAOYSA-N CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1 Chemical compound CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1 DDSKAVRLRVBOSA-UHFFFAOYSA-N 0.000 description 1
- JAAQLLYTZLRKPI-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CC(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CC(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCl)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl JAAQLLYTZLRKPI-UHFFFAOYSA-N 0.000 description 1
- IRLMQUIDFCXYPO-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCOCC(=O)OCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.COCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(OCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CC=CC=C1.[H]N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCOCC(=O)OCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.COCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(OCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CC=CC=C1.[H]N(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl IRLMQUIDFCXYPO-UHFFFAOYSA-N 0.000 description 1
- GPBZXNSTMNBMOC-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.N=C(NC1=CN(C2=CC=CN=C2)N=C1Cl)C1CC1.O=C(CC(F)(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCCCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.N=C(NC1=CN(C2=CC=CN=C2)N=C1Cl)C1CC1.O=C(CC(F)(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl GPBZXNSTMNBMOC-UHFFFAOYSA-N 0.000 description 1
- LIAZFMKIVFEGQN-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCN1CCCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)OCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCF)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCN1CCCC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(C)(C)OC(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)N(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)OCCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl LIAZFMKIVFEGQN-UHFFFAOYSA-N 0.000 description 1
- AAQPAALEWFQWQU-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCN1CCCC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCN1CCCC1)C1=CN(C2=CC=CN=C2)N=C1Cl AAQPAALEWFQWQU-UHFFFAOYSA-N 0.000 description 1
- KEBLSAORLBPXRT-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl KEBLSAORLBPXRT-UHFFFAOYSA-N 0.000 description 1
- QJTYLITWIRHQSI-UHFFFAOYSA-N CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl QJTYLITWIRHQSI-UHFFFAOYSA-N 0.000 description 1
- FDAAQEXRVZILDE-UHFFFAOYSA-N CC(C)(C)OC(=O)NC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)NC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl FDAAQEXRVZILDE-UHFFFAOYSA-N 0.000 description 1
- GVZYHRUYHYTFIR-UHFFFAOYSA-N CC(C)(C)OC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1.CC(C)(C)OC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C1CC1 Chemical compound CC(C)(C)OC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1.CC(C)(C)OC(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C1CC1 GVZYHRUYHYTFIR-UHFFFAOYSA-N 0.000 description 1
- SJOOJTJTUHLMHS-UHFFFAOYSA-N CC(C)(C)OC(=O)NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C)(C)OC(=O)NC1=CN(C2=CC=CN=C2)N=C1Cl SJOOJTJTUHLMHS-UHFFFAOYSA-N 0.000 description 1
- FANBQIYELKQGIS-UHFFFAOYSA-N CC(C)(C)OC(=O)NC1=CNN=C1Cl Chemical compound CC(C)(C)OC(=O)NC1=CNN=C1Cl FANBQIYELKQGIS-UHFFFAOYSA-N 0.000 description 1
- VFSBYVVZAUWDQD-UHFFFAOYSA-N CC(C)(C)[Si](OCCC1CC1(F)F)(C1=CC=CC=C1)C1=CC=CC=C1 Chemical compound CC(C)(C)[Si](OCCC1CC1(F)F)(C1=CC=CC=C1)C1=CC=CC=C1 VFSBYVVZAUWDQD-UHFFFAOYSA-N 0.000 description 1
- MHNYBRAZXXGYNJ-UHFFFAOYSA-N CC(C)C(=O)CC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.CC1=CC(N2C=C(NC(=O)C(C)C)C(Cl)=N2)=CN=C1.CC1=CN=CC(N2C=C(NC(=O)CCC(F)(F)F)C(Cl)=N2)=C1.CCCC(=O)CC1=CN(C2=CC(OC)=CN=C2)N=C1Cl.COC1=CN=CC(N2C=C(CC(=O)C(C)C)C(Cl)=N2)=C1.O=C(CCC(F)(F)F)CC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.O=C(CCC(F)(F)F)NC1=CN(C2=CC(Br)=CN=C2)N=C1Cl Chemical compound CC(C)C(=O)CC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.CC1=CC(N2C=C(NC(=O)C(C)C)C(Cl)=N2)=CN=C1.CC1=CN=CC(N2C=C(NC(=O)CCC(F)(F)F)C(Cl)=N2)=C1.CCCC(=O)CC1=CN(C2=CC(OC)=CN=C2)N=C1Cl.COC1=CN=CC(N2C=C(CC(=O)C(C)C)C(Cl)=N2)=C1.O=C(CCC(F)(F)F)CC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl.O=C(CCC(F)(F)F)NC1=CN(C2=CC(Br)=CN=C2)N=C1Cl MHNYBRAZXXGYNJ-UHFFFAOYSA-N 0.000 description 1
- HTPIOFZXJCTISI-UHFFFAOYSA-N CC(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound CC(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1 HTPIOFZXJCTISI-UHFFFAOYSA-N 0.000 description 1
- VHDVQARZIJEYJA-UHFFFAOYSA-N CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1.CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1CO Chemical compound CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1.CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1CO VHDVQARZIJEYJA-UHFFFAOYSA-N 0.000 description 1
- AHBQNDHXUOFFCN-UHFFFAOYSA-N CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C=O Chemical compound CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1C=O AHBQNDHXUOFFCN-UHFFFAOYSA-N 0.000 description 1
- NDYRJPYORSDVDO-UHFFFAOYSA-N CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1CCl Chemical compound CC(C)C(=O)NC1=CN(C2=CC(F)=CN=C2)N=C1CCl NDYRJPYORSDVDO-UHFFFAOYSA-N 0.000 description 1
- UZQUTDSDDCXXPP-UHFFFAOYSA-N CC(C)CC(CC(F)(F)F)SC(=O)C1=CC=CC=C1 Chemical compound CC(C)CC(CC(F)(F)F)SC(=O)C1=CC=CC=C1 UZQUTDSDDCXXPP-UHFFFAOYSA-N 0.000 description 1
- OJOCPDNEVAXBJC-UHFFFAOYSA-N CC(C)CC(I)CC(F)(F)F Chemical compound CC(C)CC(I)CC(F)(F)F OJOCPDNEVAXBJC-UHFFFAOYSA-N 0.000 description 1
- IPHKYDLHNJWPNS-UHFFFAOYSA-N CC(C/S(C)=N/C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=C(C)SC(C)=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC(C)=NO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC=CS1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CSC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(C/S(C)=N/C#N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=C(C)SC(C)=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC(C)=NO1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CC=CS1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC1=CSC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC)C1=CN(C2=CC=CN=C2)N=C1Cl IPHKYDLHNJWPNS-UHFFFAOYSA-N 0.000 description 1
- PMZAHDNDXBAWOM-UHFFFAOYSA-N CC(CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(C)(=O)=O Chemical compound CC(CC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)S(C)(=O)=O PMZAHDNDXBAWOM-UHFFFAOYSA-N 0.000 description 1
- MRUZKMPRTUMHAJ-UHFFFAOYSA-N CC(CC(F)(F)F)C(=O)NC1=CN(C2=CC=CN=C2)N=C1 Chemical compound CC(CC(F)(F)F)C(=O)NC1=CN(C2=CC=CN=C2)N=C1 MRUZKMPRTUMHAJ-UHFFFAOYSA-N 0.000 description 1
- JXPIWEMQEVXJTB-NGEXZWDXSA-N CC(CC1=CC=CS1)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CN/C=C\C=N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CC1=CC=CS1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(CC1=CC=CS1)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC(CN/C=C\C=N)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)CC1=CC=CS1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)SC1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=C\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl JXPIWEMQEVXJTB-NGEXZWDXSA-N 0.000 description 1
- BELZMHGVXWOYQZ-UHFFFAOYSA-N CC(CSC(F)(F)F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC(CSC(F)(F)F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl BELZMHGVXWOYQZ-UHFFFAOYSA-N 0.000 description 1
- HBYLLDRUQBIELY-UHFFFAOYSA-N CC(CSC)C(N(CCO[Si](C)(C)C(C)(C)C)c1c[n](-c2cccnc2)nc1Cl)=O Chemical compound CC(CSC)C(N(CCO[Si](C)(C)C(C)(C)C)c1c[n](-c2cccnc2)nc1Cl)=O HBYLLDRUQBIELY-UHFFFAOYSA-N 0.000 description 1
- VDHNVQTZZQKYKU-UHFFFAOYSA-N CC(OC1CCOC1)C(=O)O Chemical compound CC(OC1CCOC1)C(=O)O VDHNVQTZZQKYKU-UHFFFAOYSA-N 0.000 description 1
- RIHWEDPRWHWNQY-VKAVYKQESA-N CC/N=C(\SCC)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC/N=C(\SCC)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl RIHWEDPRWHWNQY-VKAVYKQESA-N 0.000 description 1
- SXNYRQCPJVPQOR-UHFFFAOYSA-N CC1=C(NC(=O)OC(C)(C)C)C=NN1C1=CC=CN=C1 Chemical compound CC1=C(NC(=O)OC(C)(C)C)C=NN1C1=CC=CN=C1 SXNYRQCPJVPQOR-UHFFFAOYSA-N 0.000 description 1
- FNJQUWXKBMXVOS-UHFFFAOYSA-N CC1=CC=C(S(=O)(=O)OCCC2CC2(F)F)C=C1 Chemical compound CC1=CC=C(S(=O)(=O)OCCC2CC2(F)F)C=C1 FNJQUWXKBMXVOS-UHFFFAOYSA-N 0.000 description 1
- POSQJBGGNHQSDC-UHFFFAOYSA-N CC1=CC=NN1C1=CC=CN=C1.CC1=NN(C2=CC=CN=C2)C=C1 Chemical compound CC1=CC=NN1C1=CC=CN=C1.CC1=NN(C2=CC=CN=C2)C=C1 POSQJBGGNHQSDC-UHFFFAOYSA-N 0.000 description 1
- VGTJSJMKDXQIRB-UHFFFAOYSA-N CC1=CN=CC(N2C=C(N(C)C(=O)C(F)(F)F)C(Cl)=N2)=C1 Chemical compound CC1=CN=CC(N2C=C(N(C)C(=O)C(F)(F)F)C(Cl)=N2)=C1 VGTJSJMKDXQIRB-UHFFFAOYSA-N 0.000 description 1
- XDWOWCXWFXVFDP-UHFFFAOYSA-N CC1=CN=CC(N2C=C(NC(=O)C(F)(F)F)C(Cl)=N2)=C1 Chemical compound CC1=CN=CC(N2C=C(NC(=O)C(F)(F)F)C(Cl)=N2)=C1 XDWOWCXWFXVFDP-UHFFFAOYSA-N 0.000 description 1
- HLHVAFOHHUSOFK-UHFFFAOYSA-N CC1=NN(C2=CC(F)=CN=C2)C=C1N Chemical compound CC1=NN(C2=CC(F)=CN=C2)C=C1N HLHVAFOHHUSOFK-UHFFFAOYSA-N 0.000 description 1
- GCZJWTLRJGSWBK-UHFFFAOYSA-N CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=O)OC(C)(C)C.CCOC1=C(NC(=O)OC(C)(C)C)C(C)=NN1C1=CC(F)=CN=C1 Chemical compound CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=O)OC(C)(C)C.CCOC1=C(NC(=O)OC(C)(C)C)C(C)=NN1C1=CC(F)=CN=C1 GCZJWTLRJGSWBK-UHFFFAOYSA-N 0.000 description 1
- PFBLHMSZMNWVAL-UHFFFAOYSA-N CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=S)N1CCOC1=O Chemical compound CC1=NN(C2=CC(F)=CN=C2)C=C1NC(=S)N1CCOC1=O PFBLHMSZMNWVAL-UHFFFAOYSA-N 0.000 description 1
- QLPHVPLKQCEGTH-UHFFFAOYSA-N CC1=NN(C2=CC=CN=C2)C=C1N(CC1=CC=CC=C1)C(=O)OC(C)(C)C.CCCN(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1C.CCN(C(=O)C(C)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)OCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C1CCSC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC1=NN(C2=CC=CN=C2)C=C1N(CC1=CC=CC=C1)C(=O)OC(C)(C)C.CCCN(C(=O)OC(C)(C)C)C1=C(F)N(C2=CC=CN=C2)N=C1C.CCN(C(=O)C(C)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C(C)OCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)C1CCSC1)C1=CN(C2=CC=CN=C2)N=C1Cl QLPHVPLKQCEGTH-UHFFFAOYSA-N 0.000 description 1
- MDGGPGMWDDNDRK-UHFFFAOYSA-N CC1=NN(C2=CC=CN=C2)C=C1N=C=S Chemical compound CC1=NN(C2=CC=CN=C2)C=C1N=C=S MDGGPGMWDDNDRK-UHFFFAOYSA-N 0.000 description 1
- DPYZXAYHYMNDKA-UHFFFAOYSA-N CC1=NN(C2=CC=CN=C2)C=C1NC(=S)N1CCOC1=O Chemical compound CC1=NN(C2=CC=CN=C2)C=C1NC(=S)N1CCOC1=O DPYZXAYHYMNDKA-UHFFFAOYSA-N 0.000 description 1
- XHUZCPMXOOTMOH-UHFFFAOYSA-N CC1=NN(C2=CC=CN=C2)C=C1NC1CC1 Chemical compound CC1=NN(C2=CC=CN=C2)C=C1NC1CC1 XHUZCPMXOOTMOH-UHFFFAOYSA-N 0.000 description 1
- DWYXAWLYTFUADV-UHFFFAOYSA-N CC1CC1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1CC1C(=O)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCNC(=S)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(C1CC1(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(C1CC1)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CC1CC1C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CC1CC1C(=O)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCNC(=S)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(C1CC1(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(C1CC1)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl DWYXAWLYTFUADV-UHFFFAOYSA-N 0.000 description 1
- OPEITBWCEQGRJP-UHFFFAOYSA-N CCC(CC(=O)O)SC Chemical compound CCC(CC(=O)O)SC OPEITBWCEQGRJP-UHFFFAOYSA-N 0.000 description 1
- RFOJCUUXLBMZIU-UHFFFAOYSA-N CCC(Cl)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCC(Cl)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl RFOJCUUXLBMZIU-UHFFFAOYSA-N 0.000 description 1
- SVQPORACSJHCOU-UHFFFAOYSA-N CCC(SC(C)=O)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCC(SC(C)=O)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl SVQPORACSJHCOU-UHFFFAOYSA-N 0.000 description 1
- KRAYDFJFPCPQRV-UHFFFAOYSA-N CCC1=NN(C2=CC(F)=CN=C2)C=C1N(C)C(=O)OC(C)(C)C Chemical compound CCC1=NN(C2=CC(F)=CN=C2)C=C1N(C)C(=O)OC(C)(C)C KRAYDFJFPCPQRV-UHFFFAOYSA-N 0.000 description 1
- OOGKHRNVRRJWRS-UHFFFAOYSA-N CCCC(CC(=O)O)SC Chemical compound CCCC(CC(=O)O)SC OOGKHRNVRRJWRS-UHFFFAOYSA-N 0.000 description 1
- YDHWNBMOYJUIFM-UHFFFAOYSA-N CCCCNC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCCCNC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl YDHWNBMOYJUIFM-UHFFFAOYSA-N 0.000 description 1
- CBBJVTXIBPJROQ-UHFFFAOYSA-N CCCO[Si](C)(C)C(C)(C)C.CSCC(C)C(=O)NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCCO[Si](C)(C)C(C)(C)C.CSCC(C)C(=O)NC1=CN(C2=CC=CN=C2)N=C1Cl CBBJVTXIBPJROQ-UHFFFAOYSA-N 0.000 description 1
- TXMNIPKTQCGUSG-OLXJCRAFSA-J CCC[V](C)I.CCC[V](I)(I)I.CSC(CC(=O)O)C(F)(F)F.O=C(O)/C=C/C(F)(F)F Chemical compound CCC[V](C)I.CCC[V](I)(I)I.CSC(CC(=O)O)C(F)(F)F.O=C(O)/C=C/C(F)(F)F TXMNIPKTQCGUSG-OLXJCRAFSA-J 0.000 description 1
- BFGRVAWBOAHPAM-AATRIKPKSA-N CCN(C(=O)/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl BFGRVAWBOAHPAM-AATRIKPKSA-N 0.000 description 1
- ULWCOOHUCFSTPU-ZZXKWVIFSA-N CCN(C(=O)/C=C/CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)/C=C/CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl ULWCOOHUCFSTPU-ZZXKWVIFSA-N 0.000 description 1
- ZUTQGOLXUJKYQL-KGRQPLLXSA-N CCN(C(=O)/C=C/CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCC1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=N\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=N\N=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CN(N)/C=C\N)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)/C=C/CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC#N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NCC1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=N\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CCN/C=N\N=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CN(N)/C=C\N)C1=CN(C2=CC=CN=C2)N=C1Cl ZUTQGOLXUJKYQL-KGRQPLLXSA-N 0.000 description 1
- KBFLOBLLZOANIW-HJALNALPSA-N CCN(C(=O)C(C)C(C)SC)C1=CN(C2=CC(F)=CN=C2)N=C1Cl.[H]/C(C)=C(\C)C(=O)N(CC)C1=CN(C2=CC(F)=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)C(C)SC)C1=CN(C2=CC(F)=CN=C2)N=C1Cl.[H]/C(C)=C(\C)C(=O)N(CC)C1=CN(C2=CC(F)=CN=C2)N=C1Cl KBFLOBLLZOANIW-HJALNALPSA-N 0.000 description 1
- KEEWNEGBRIMFFN-UHFFFAOYSA-N CCN(C(=O)C(C)C)C1=CC(C2=CC=CN=C2)=NN1C Chemical compound CCN(C(=O)C(C)C)C1=CC(C2=CC=CN=C2)=NN1C KEEWNEGBRIMFFN-UHFFFAOYSA-N 0.000 description 1
- DTESUUAOSUTYDD-UHFFFAOYSA-N CCN(C(=O)C(C)CS(C)(=O)=NC#N)C1=CN(C2=CC(F)=CN=C2)N=C1C Chemical compound CCN(C(=O)C(C)CS(C)(=O)=NC#N)C1=CN(C2=CC(F)=CN=C2)N=C1C DTESUUAOSUTYDD-UHFFFAOYSA-N 0.000 description 1
- PVMFWOKVGCXOJN-UHFFFAOYSA-N CCN(C(=O)C(C)CS(C)=O)C1=CN(C2=CN=CC=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)CS(C)=O)C1=CN(C2=CN=CC=C2)N=C1Cl PVMFWOKVGCXOJN-UHFFFAOYSA-N 0.000 description 1
- ABBUICSXAWMQOV-UHFFFAOYSA-N CCN(C(=O)C(C)CS)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)CS)C1=CN(C2=CC=CN=C2)N=C1Cl ABBUICSXAWMQOV-UHFFFAOYSA-N 0.000 description 1
- DEVKDYOQPKAFJM-UHFFFAOYSA-N CCN(C(=O)C(C)CSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)CSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl DEVKDYOQPKAFJM-UHFFFAOYSA-N 0.000 description 1
- OSRSWOHGKMMJDL-UHFFFAOYSA-N CCN(C(=O)C(C)CSCCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)CSCCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CN(C2=CC=CN=C2)N=C1Cl OSRSWOHGKMMJDL-UHFFFAOYSA-N 0.000 description 1
- JEVIPWBRZGNJTH-UHFFFAOYSA-N CCN(C(=O)C(C)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl JEVIPWBRZGNJTH-UHFFFAOYSA-N 0.000 description 1
- RYLKOSGQMAKJDW-UHFFFAOYSA-N CCN(C(=O)C(C)OCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)OCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl RYLKOSGQMAKJDW-UHFFFAOYSA-N 0.000 description 1
- QZMCSMMOZLDIAQ-UHFFFAOYSA-N CCN(C(=O)C(C)OCSC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)OCSC)C1=CN(C2=CC=CN=C2)N=C1Cl QZMCSMMOZLDIAQ-UHFFFAOYSA-N 0.000 description 1
- HWRKDLXWWWMUBP-UHFFFAOYSA-N CCN(C(=O)C(C)OCSC)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(CN1C=CN=C1)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)OCSC)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)CN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(CN1C=CN=C1)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl HWRKDLXWWWMUBP-UHFFFAOYSA-N 0.000 description 1
- FCTUAVSCPYGQLO-UHFFFAOYSA-N CCN(C(=O)C(C)OS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)OS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl FCTUAVSCPYGQLO-UHFFFAOYSA-N 0.000 description 1
- BCWMOBYQEZFGFV-UHFFFAOYSA-N CCN(C(=O)C(C)SC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)SC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl BCWMOBYQEZFGFV-UHFFFAOYSA-N 0.000 description 1
- QQJJBWNWDFBBAB-UHFFFAOYSA-N CCN(C(=O)C(C)SC=CF)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)SC=CF)C1=CN(C2=CC=CN=C2)N=C1Cl QQJJBWNWDFBBAB-UHFFFAOYSA-N 0.000 description 1
- PAWXXBDYIWPDEF-UHFFFAOYSA-N CCN(C(=O)C(C)SCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C(C)SCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl PAWXXBDYIWPDEF-UHFFFAOYSA-N 0.000 description 1
- LEDGRLITEWGQKX-UHFFFAOYSA-N CCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl LEDGRLITEWGQKX-UHFFFAOYSA-N 0.000 description 1
- UUKGVKGDSWGIPY-UHFFFAOYSA-N CCN(C(=O)C1CN1C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC(S)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC1=NN=NN1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN(C1=CC=CC=C1)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1(Br)CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)C1CN1C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CC(S)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC1=NN=NN1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN(C1=CC=CC=C1)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CN(C(=O)C1(Br)CC1)C1=CN(C2=CC=CN=C2)N=C1Cl UUKGVKGDSWGIPY-UHFFFAOYSA-N 0.000 description 1
- DFQIPTQKALQDNX-UHFFFAOYSA-N CCN(C(=O)CC(C)S(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CC(C)S(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl DFQIPTQKALQDNX-UHFFFAOYSA-N 0.000 description 1
- PVJSOPGTHDHVEI-UHFFFAOYSA-N CCN(C(=O)CC(OC)(C(F)(F)F)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1C Chemical compound CCN(C(=O)CC(OC)(C(F)(F)F)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1C PVJSOPGTHDHVEI-UHFFFAOYSA-N 0.000 description 1
- QWOLHCMDSHJERF-UHFFFAOYSA-N CCN(C(=O)CC(SC(C)=O)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CC(SC(C)=O)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl QWOLHCMDSHJERF-UHFFFAOYSA-N 0.000 description 1
- PZTBNVXRCWYKBW-UHFFFAOYSA-N CCN(C(=O)CCC(=O)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC(=O)O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(OC(F)(F)F)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(OC)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC(=O)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC(=O)O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCC=O)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(OC(F)(F)F)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(OC)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl PZTBNVXRCWYKBW-UHFFFAOYSA-N 0.000 description 1
- ZRHVEIZYXXLZRH-UHFFFAOYSA-N CCN(C(=O)CCC(=O)CCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC(=O)CCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl ZRHVEIZYXXLZRH-UHFFFAOYSA-N 0.000 description 1
- MLGKFGMMHUOAFG-UHFFFAOYSA-N CCN(C(=O)CCC(=O)O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC(=O)O)C1=CN(C2=CC=CN=C2)N=C1Cl MLGKFGMMHUOAFG-UHFFFAOYSA-N 0.000 description 1
- YUXKDJMUGAUASB-UHFFFAOYSA-N CCN(C(=O)CCC(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC(=O)OCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YUXKDJMUGAUASB-UHFFFAOYSA-N 0.000 description 1
- YAGWRJCMVGNUOC-UHFFFAOYSA-N CCN(C(=O)CCC(=O)SCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC(=O)SCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YAGWRJCMVGNUOC-UHFFFAOYSA-N 0.000 description 1
- KMUYDZGQDQPHOK-UHFFFAOYSA-N CCN(C(=O)CCC1=NN=NN1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC1=NN=NN1)C1=CN(C2=CC=CN=C2)N=C1Cl KMUYDZGQDQPHOK-UHFFFAOYSA-N 0.000 description 1
- RSHLYIHGKYWLEK-UHFFFAOYSA-N CCN(C(=O)CCC=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCC=O)C1=CN(C2=CC=CN=C2)N=C1Cl RSHLYIHGKYWLEK-UHFFFAOYSA-N 0.000 description 1
- KYFKSEAJLWNZCD-UHFFFAOYSA-N CCN(C(=O)CCN(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCN(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl KYFKSEAJLWNZCD-UHFFFAOYSA-N 0.000 description 1
- CLFAWRWOFMZWON-UHFFFAOYSA-N CCN(C(=O)CCN(CCC(F)(F)F)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCN(CCC(F)(F)F)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl CLFAWRWOFMZWON-UHFFFAOYSA-N 0.000 description 1
- HMFSROWPMCQYOU-UHFFFAOYSA-N CCN(C(=O)CCN/C=N\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN/C=N\N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1C=CN=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1N=CC=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1N=CN=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.N Chemical compound CCN(C(=O)CCN/C=N\C=N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN/C=N\N)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CCN1C=CN=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1C=CN=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1N=CC=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)CN1N=CN=N1)C1=CN(C2=CC=CN=C2)N=C1Cl.N HMFSROWPMCQYOU-UHFFFAOYSA-N 0.000 description 1
- YSXJZAZKHKQKSW-UHFFFAOYSA-N CCN(C(=O)CCNCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCNCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YSXJZAZKHKQKSW-UHFFFAOYSA-N 0.000 description 1
- XSJFSCKWJXNOHI-UHFFFAOYSA-N CCN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCNS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl XSJFSCKWJXNOHI-UHFFFAOYSA-N 0.000 description 1
- BNYAEGXPYFQSJD-UHFFFAOYSA-N CCN(C(=O)CCS(=O)(=O)N(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(=O)(=O)N(C)CCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl BNYAEGXPYFQSJD-UHFFFAOYSA-N 0.000 description 1
- YEOYRODOIOPWQG-UHFFFAOYSA-N CCN(C(=O)CCS(=O)CC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(=O)CC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YEOYRODOIOPWQG-UHFFFAOYSA-N 0.000 description 1
- FMVNJGMMWZGLFY-UHFFFAOYSA-N CCN(C(=O)CCS(C)(=O)=NC(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(C)(=O)=NC(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl FMVNJGMMWZGLFY-UHFFFAOYSA-N 0.000 description 1
- AOZKRHRZAOXRBK-UHFFFAOYSA-N CCN(C(=O)CCS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl AOZKRHRZAOXRBK-UHFFFAOYSA-N 0.000 description 1
- NCVGKXYPVWONBO-UHFFFAOYSA-N CCN(C(=O)CCS(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl NCVGKXYPVWONBO-UHFFFAOYSA-N 0.000 description 1
- JGGBPCYHTHFRNS-UHFFFAOYSA-N CCN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl JGGBPCYHTHFRNS-UHFFFAOYSA-N 0.000 description 1
- CJZSMPLPSQGSAV-RMKNXTFCSA-N CCN(C(=O)CCS/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCS/C=C/C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl CJZSMPLPSQGSAV-RMKNXTFCSA-N 0.000 description 1
- BYJPTKNHPJYNFN-UHFFFAOYSA-N CCN(C(=O)CCSC(CC(C)C)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSC(CC(C)C)CC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl BYJPTKNHPJYNFN-UHFFFAOYSA-N 0.000 description 1
- TVGSMMKNMGGYFF-UHFFFAOYSA-N CCN(C(=O)CCSC(Cl)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSC(Cl)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl TVGSMMKNMGGYFF-UHFFFAOYSA-N 0.000 description 1
- KDCGMZBPNZNOHE-UHFFFAOYSA-N CCN(C(=O)CCSC1CC(F)(F)C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSC1CC(F)(F)C1)C1=CN(C2=CC=CN=C2)N=C1Cl KDCGMZBPNZNOHE-UHFFFAOYSA-N 0.000 description 1
- DBVSTNGBZRXHIA-UHFFFAOYSA-N CCN(C(=O)CCSCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C1=CN(C2=CC=CN=C2)N=C1Cl DBVSTNGBZRXHIA-UHFFFAOYSA-N 0.000 description 1
- CDMXOHDWVLUOQA-UHFFFAOYSA-N CCN(C(=O)CCSCC(C)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC(C)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl CDMXOHDWVLUOQA-UHFFFAOYSA-N 0.000 description 1
- DUHOCWMGSDAAFP-UHFFFAOYSA-N CCN(C(=O)CCSCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl DUHOCWMGSDAAFP-UHFFFAOYSA-N 0.000 description 1
- CSEZGNNRHRGCMT-UHFFFAOYSA-N CCN(C(=O)CCSCC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC1CC1(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl CSEZGNNRHRGCMT-UHFFFAOYSA-N 0.000 description 1
- GLGIRZDQQVDMLL-UHFFFAOYSA-N CCN(C(=O)CCSCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl GLGIRZDQQVDMLL-UHFFFAOYSA-N 0.000 description 1
- WMPOKEBOPNOIQY-UHFFFAOYSA-N CCN(C(=O)CCSCC=C(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCC=C(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl WMPOKEBOPNOIQY-UHFFFAOYSA-N 0.000 description 1
- YFXKLLJXXQACJB-UHFFFAOYSA-N CCN(C(=O)CCSCCC(=O)NC1=C(C)C=C(C)C=C1C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCCC(=O)NC1=C(C)C=C(C)C=C1C)C1=CN(C2=CC=CN=C2)N=C1Cl YFXKLLJXXQACJB-UHFFFAOYSA-N 0.000 description 1
- VRTHVWUDYHFPJU-UHFFFAOYSA-N CCN(C(=O)CCSCCC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCCC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl VRTHVWUDYHFPJU-UHFFFAOYSA-N 0.000 description 1
- MSUUHXCBPJUTOH-UHFFFAOYSA-N CCN(C(=O)CCSCCC(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CCSCCC(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl MSUUHXCBPJUTOH-UHFFFAOYSA-N 0.000 description 1
- SEXCNYNIFAPWNV-UHFFFAOYSA-N CCN(C(=O)CN(C)C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CN(C)C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl SEXCNYNIFAPWNV-UHFFFAOYSA-N 0.000 description 1
- BYDIHZWWLGZFFR-UHFFFAOYSA-N CCN(C(=O)CN(C)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CN(C)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl BYDIHZWWLGZFFR-UHFFFAOYSA-N 0.000 description 1
- FKLBHAWFNMLQBQ-UHFFFAOYSA-N CCN(C(=O)COC(C)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCCOC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=C(Cl)C=CC(Cl)=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(C)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=CC=C1F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)COC(C)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)COCCOC)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=C(Cl)C=CC(Cl)=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=C(C)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl.CCN(C(=O)NC(=O)C1=CC=CC=C1F)C1=CN(C2=CC=CN=C2)N=C1Cl FKLBHAWFNMLQBQ-UHFFFAOYSA-N 0.000 description 1
- TUDFBPVFUNGJBM-UHFFFAOYSA-N CCN(C(=O)COC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)COC)C1=CN(C2=CC=CN=C2)N=C1Cl TUDFBPVFUNGJBM-UHFFFAOYSA-N 0.000 description 1
- PQDZMBIXOPWMOK-UHFFFAOYSA-N CCN(C(=O)COCCOC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)COCCOC)C1=CN(C2=CC=CN=C2)N=C1Cl PQDZMBIXOPWMOK-UHFFFAOYSA-N 0.000 description 1
- RYGSNXMVEMJHRD-UHFFFAOYSA-N CCN(C(=O)CSC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CSC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl RYGSNXMVEMJHRD-UHFFFAOYSA-N 0.000 description 1
- YLCGUSNZEKJOSE-UHFFFAOYSA-N CCN(C(=O)CSC(Cl)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CSC(Cl)C(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl YLCGUSNZEKJOSE-UHFFFAOYSA-N 0.000 description 1
- FVLLEJVDZLURJS-UHFFFAOYSA-N CCN(C(=O)CSCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)CSCC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl FVLLEJVDZLURJS-UHFFFAOYSA-N 0.000 description 1
- QEHWHCKWUPFKHL-UHFFFAOYSA-N CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C(=O)C(C)(C)C Chemical compound CCN(C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl)C(=O)C(C)(C)C QEHWHCKWUPFKHL-UHFFFAOYSA-N 0.000 description 1
- XLNOOHCUDXIHFY-UHFFFAOYSA-N CCN(C(=O)NC(=O)C1=CC=C(OC)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)NC(=O)C1=CC=C(OC)C=C1)C1=CN(C2=CC=CN=C2)N=C1Cl XLNOOHCUDXIHFY-UHFFFAOYSA-N 0.000 description 1
- GQQCYKJHWMSDLZ-UHFFFAOYSA-N CCN(C(=O)NCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)NCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl GQQCYKJHWMSDLZ-UHFFFAOYSA-N 0.000 description 1
- CEBNNKFYAYIFFP-UHFFFAOYSA-N CCN(C(=O)OCCSCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)OCCSCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl CEBNNKFYAYIFFP-UHFFFAOYSA-N 0.000 description 1
- FRAMMVRMRFSYIB-UHFFFAOYSA-N CCN(C(=O)SC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)SC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1Cl FRAMMVRMRFSYIB-UHFFFAOYSA-N 0.000 description 1
- XEZSUASJIHWCPW-UHFFFAOYSA-N CCN(C(=O)SC)C1=C(SC)N(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=O)SC)C1=C(SC)N(C2=CC=CN=C2)N=C1Cl XEZSUASJIHWCPW-UHFFFAOYSA-N 0.000 description 1
- JZMJSVUMOGLBAZ-UHFFFAOYSA-N CCN(C(=S)C(C)CSC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(=S)C(C)CSC)C1=CN(C2=CC=CN=C2)N=C1Cl JZMJSVUMOGLBAZ-UHFFFAOYSA-N 0.000 description 1
- PKDPPSRHDLFNQB-UHFFFAOYSA-N CCN(C(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C(N)=O)C1=CN(C2=CC=CN=C2)N=C1Cl PKDPPSRHDLFNQB-UHFFFAOYSA-N 0.000 description 1
- YLWRWIWCOLATLR-UHFFFAOYSA-N CCN(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCN(C)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl YLWRWIWCOLATLR-UHFFFAOYSA-N 0.000 description 1
- DRPRUZBSBWWENX-UHFFFAOYSA-N CCNC(=O)N(C(=O)CCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCNC(=O)N(C(=O)CCSCCC(F)(F)F)C1=CN(C2=CC=CN=C2)N=C1Cl DRPRUZBSBWWENX-UHFFFAOYSA-N 0.000 description 1
- KMVXKGNTZUXSDE-UHFFFAOYSA-N CCNC(=O)NC1=CN(C2=CC=CN=C2)N=C1C Chemical compound CCNC(=O)NC1=CN(C2=CC=CN=C2)N=C1C KMVXKGNTZUXSDE-UHFFFAOYSA-N 0.000 description 1
- SXUMSCJUXIVSFX-UHFFFAOYSA-N CCNC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CCNC1=CN(C2=CC=CN=C2)N=C1Cl SXUMSCJUXIVSFX-UHFFFAOYSA-N 0.000 description 1
- PAILVKQSHRJIPE-UHFFFAOYSA-N CCOC(=O)C1(CO)CC1 Chemical compound CCOC(=O)C1(CO)CC1 PAILVKQSHRJIPE-UHFFFAOYSA-N 0.000 description 1
- NAWXPGOSDIZRJJ-UHFFFAOYSA-N CCOC(=O)C1(COS(C)(=O)=O)CC1 Chemical compound CCOC(=O)C1(COS(C)(=O)=O)CC1 NAWXPGOSDIZRJJ-UHFFFAOYSA-N 0.000 description 1
- BEIKQPGSFJAROZ-UHFFFAOYSA-N CCOC(=O)C1(CSC)CC1 Chemical compound CCOC(=O)C1(CSC)CC1 BEIKQPGSFJAROZ-UHFFFAOYSA-N 0.000 description 1
- KEZRDVJRXLTVOY-UHFFFAOYSA-N CCOP(=O)(CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl)OCC Chemical compound CCOP(=O)(CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl)OCC KEZRDVJRXLTVOY-UHFFFAOYSA-N 0.000 description 1
- YUUHMXFOCJSFSM-UHFFFAOYSA-N CN(C(=O)CCN(CC#N)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)CCN(CC#N)S(C)(=O)=O)C1=CN(C2=CC=CN=C2)N=C1Cl YUUHMXFOCJSFSM-UHFFFAOYSA-N 0.000 description 1
- UCIRAXFLLAMNRC-UHFFFAOYSA-N CN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)CCS)C1=CN(C2=CC=CN=C2)N=C1Cl UCIRAXFLLAMNRC-UHFFFAOYSA-N 0.000 description 1
- BZPCJCUVFHJMTM-UHFFFAOYSA-N CN(C(=O)CCSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)CCSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)C1=CN(C2=CC=CN=C2)N=C1Cl BZPCJCUVFHJMTM-UHFFFAOYSA-N 0.000 description 1
- ZLYFUROLKCVKRA-UHFFFAOYSA-N CN(C(=O)CCSCC=C(Cl)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)CCSCC=C(Cl)Cl)C1=CN(C2=CC=CN=C2)N=C1Cl ZLYFUROLKCVKRA-UHFFFAOYSA-N 0.000 description 1
- HCNCFCUIFLEUOY-UHFFFAOYSA-N CN(C(=O)OC(C)(C)C)C1=C(Br)N(C2=CC=CN=C2)N=C1 Chemical compound CN(C(=O)OC(C)(C)C)C1=C(Br)N(C2=CC=CN=C2)N=C1 HCNCFCUIFLEUOY-UHFFFAOYSA-N 0.000 description 1
- WACYBHRTAQFVNE-UHFFFAOYSA-N CN(C(=O)OC(C)(C)C)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl Chemical compound CN(C(=O)OC(C)(C)C)C1=CN(C2=CC(Cl)=CN=C2)N=C1Cl WACYBHRTAQFVNE-UHFFFAOYSA-N 0.000 description 1
- UISNFTLLCIKXIY-UHFFFAOYSA-N CN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound CN(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 UISNFTLLCIKXIY-UHFFFAOYSA-N 0.000 description 1
- GFMKSUCHQMFMHR-QWHCGFSZSA-N CN(C(=O)[C@@H]1C=C[C@H](CS(C)(=O)=O)C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)[C@@H]1C=C[C@H](CS(C)(=O)=O)C1)C1=CN(C2=CC=CN=C2)N=C1Cl GFMKSUCHQMFMHR-QWHCGFSZSA-N 0.000 description 1
- ZPFOQSOCZXOWJF-MNOVXSKESA-N CN(C(=O)[C@@H]1C=C[C@H](N)C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(O)C(F)(F)F Chemical compound CN(C(=O)[C@@H]1C=C[C@H](N)C1)C1=CN(C2=CC=CN=C2)N=C1Cl.O=C(O)C(F)(F)F ZPFOQSOCZXOWJF-MNOVXSKESA-N 0.000 description 1
- ZWMOOUAHZVAVKN-OLZOCXBDSA-N CN(C(=O)[C@H]1CC[C@@H](CS(C)(=O)=O)C1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CN(C(=O)[C@H]1CC[C@@H](CS(C)(=O)=O)C1)C1=CN(C2=CC=CN=C2)N=C1Cl ZWMOOUAHZVAVKN-OLZOCXBDSA-N 0.000 description 1
- WMXPAHREQNDGOY-NEPJUHHUSA-N CN(C([C@@H](C1)C=C[C@@H]1NS(C)(=O)=O)=O)c1c[n](-c2cccnc2)nc1Cl Chemical compound CN(C([C@@H](C1)C=C[C@@H]1NS(C)(=O)=O)=O)c1c[n](-c2cccnc2)nc1Cl WMXPAHREQNDGOY-NEPJUHHUSA-N 0.000 description 1
- MIKNUFJXLMTEOQ-UHFFFAOYSA-N CN1N=C(C2=CC=CN=C2)C=C1N(C)C(=O)CCSCCC(F)(F)F Chemical compound CN1N=C(C2=CC=CN=C2)C=C1N(C)C(=O)CCSCCC(F)(F)F MIKNUFJXLMTEOQ-UHFFFAOYSA-N 0.000 description 1
- MHBZZOYVLCVCLJ-UHFFFAOYSA-N CN1N=C(C2=CC=CN=C2)C=C1N.CN1N=C(N)C=C1C1=CC=CN=C1 Chemical compound CN1N=C(C2=CC=CN=C2)C=C1N.CN1N=C(N)C=C1C1=CC=CN=C1 MHBZZOYVLCVCLJ-UHFFFAOYSA-N 0.000 description 1
- MXALTHAMLNPPNR-UHFFFAOYSA-N CNC1=CN(C2=CC(C)=CN=C2)N=C1Cl Chemical compound CNC1=CN(C2=CC(C)=CN=C2)N=C1Cl MXALTHAMLNPPNR-UHFFFAOYSA-N 0.000 description 1
- RFEOXNTXPBKXJY-UHFFFAOYSA-N COC(CSC)C(=O)O Chemical compound COC(CSC)C(=O)O RFEOXNTXPBKXJY-UHFFFAOYSA-N 0.000 description 1
- DYJGEWHYRHVROL-SSZFMOIBSA-N CS/C(=N\C1=CN(C2=CC=CN=C2)N=C1C)N1CCOC1=O Chemical compound CS/C(=N\C1=CN(C2=CC=CN=C2)N=C1C)N1CCOC1=O DYJGEWHYRHVROL-SSZFMOIBSA-N 0.000 description 1
- RERQKHGHVWXMAV-UHFFFAOYSA-N CSC(=CC(=O)C1=CC=CN=C1)SC Chemical compound CSC(=CC(=O)C1=CC=CN=C1)SC RERQKHGHVWXMAV-UHFFFAOYSA-N 0.000 description 1
- BDMGJGQJOJMEQF-UHFFFAOYSA-N CSC(CC(=O)O)C1=CC=CC=C1 Chemical compound CSC(CC(=O)O)C1=CC=CC=C1 BDMGJGQJOJMEQF-UHFFFAOYSA-N 0.000 description 1
- OVBQTTRKSOMLPH-UHFFFAOYSA-N CSC(CC(=O)O)C1=CC=NC=C1 Chemical compound CSC(CC(=O)O)C1=CC=NC=C1 OVBQTTRKSOMLPH-UHFFFAOYSA-N 0.000 description 1
- QFSWGFQEQUQCLR-UHFFFAOYSA-N CSC(CC(=O)O)C1=CN=CC=C1 Chemical compound CSC(CC(=O)O)C1=CN=CC=C1 QFSWGFQEQUQCLR-UHFFFAOYSA-N 0.000 description 1
- QORLYSSNLRNDOQ-UHFFFAOYSA-N CSC(CC(=O)O)C1CC1 Chemical compound CSC(CC(=O)O)C1CC1 QORLYSSNLRNDOQ-UHFFFAOYSA-N 0.000 description 1
- JNUJJJSFFVPXFO-UHFFFAOYSA-N CSC(CC(=O)O)CC(C)C Chemical compound CSC(CC(=O)O)CC(C)C JNUJJJSFFVPXFO-UHFFFAOYSA-N 0.000 description 1
- MYHANVJKRGXIQB-UHFFFAOYSA-N CSC(F)(F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSC(F)(F)C(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl MYHANVJKRGXIQB-UHFFFAOYSA-N 0.000 description 1
- CJYHPULKKCOKKB-UHFFFAOYSA-N CSC1(CC(=O)O)CCC1 Chemical compound CSC1(CC(=O)O)CCC1 CJYHPULKKCOKKB-UHFFFAOYSA-N 0.000 description 1
- CPEUNMBSAUXFLR-UHFFFAOYSA-N CSCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSCC(=O)N(C)C1=CN(C2=CC=CN=C2)N=C1Cl CPEUNMBSAUXFLR-UHFFFAOYSA-N 0.000 description 1
- HDUBTWCBEURYOK-UHFFFAOYSA-N CSCC(C(=O)O)C(F)(F)F Chemical compound CSCC(C(=O)O)C(F)(F)F HDUBTWCBEURYOK-UHFFFAOYSA-N 0.000 description 1
- FQIWBMWNNPWQTI-UHFFFAOYSA-N CSCC(C)(C)C(=O)O Chemical compound CSCC(C)(C)C(=O)O FQIWBMWNNPWQTI-UHFFFAOYSA-N 0.000 description 1
- FBGLUYDKESSKDC-UHFFFAOYSA-N CSCC(C)C(=O)N(C)C1=CC(C2=CC=CN=C2)=NN1C Chemical compound CSCC(C)C(=O)N(C)C1=CC(C2=CC=CN=C2)=NN1C FBGLUYDKESSKDC-UHFFFAOYSA-N 0.000 description 1
- OXMIQTWOTRAGKB-UHFFFAOYSA-N CSCC(C)C(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSCC(C)C(=O)N(CCO)C1=CN(C2=CC=CN=C2)N=C1Cl OXMIQTWOTRAGKB-UHFFFAOYSA-N 0.000 description 1
- SKQNKMJPTUSXFV-UHFFFAOYSA-N CSCC(C)C(=O)N(CCOC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSCC(C)C(=O)N(CCOC(C)=O)C1=CN(C2=CC=CN=C2)N=C1Cl SKQNKMJPTUSXFV-UHFFFAOYSA-N 0.000 description 1
- OEFRJRLPHLHRLE-UHFFFAOYSA-N CSCC(O)C(=O)O Chemical compound CSCC(O)C(=O)O OEFRJRLPHLHRLE-UHFFFAOYSA-N 0.000 description 1
- HSOAQEVFZVCXQW-UHFFFAOYSA-N CSCC1(C(=O)O)CC1 Chemical compound CSCC1(C(=O)O)CC1 HSOAQEVFZVCXQW-UHFFFAOYSA-N 0.000 description 1
- VGHJUBKIBKVZAN-UHFFFAOYSA-N CSCC1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O Chemical compound CSCC1CCN(C2=CN(C3=CC=CN=C3)N=C2Cl)C1=O VGHJUBKIBKVZAN-UHFFFAOYSA-N 0.000 description 1
- NKHHMAZUZBYRRX-UHFFFAOYSA-N CSCCC(=N)NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSCCC(=N)NC1=CN(C2=CC=CN=C2)N=C1Cl NKHHMAZUZBYRRX-UHFFFAOYSA-N 0.000 description 1
- APFNMBVVJCPXHT-UHFFFAOYSA-N CSCCC(=O)N(C(=O)C(C)CSC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound CSCCC(=O)N(C(=O)C(C)CSC)C1=CN(C2=CC=CN=C2)N=C1Cl APFNMBVVJCPXHT-UHFFFAOYSA-N 0.000 description 1
- XTLODZJCOSHWIW-UHFFFAOYSA-N CSCCNC(=O)N(C)C1=CC(C2=CC=CN=C2)=NN1C Chemical compound CSCCNC(=O)N(C)C1=CC(C2=CC=CN=C2)=NN1C XTLODZJCOSHWIW-UHFFFAOYSA-N 0.000 description 1
- QLCQQTWNAJHXLQ-UHFFFAOYSA-N CSCCOC(C)C(=O)O Chemical compound CSCCOC(C)C(=O)O QLCQQTWNAJHXLQ-UHFFFAOYSA-N 0.000 description 1
- CHWZUWDRNLWSPU-UHFFFAOYSA-N Cl.NC1=CNN=C1Cl Chemical compound Cl.NC1=CNN=C1Cl CHWZUWDRNLWSPU-UHFFFAOYSA-N 0.000 description 1
- SDKRLSAJIKWRMD-UHFFFAOYSA-N NC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl Chemical compound NC1=CN(C2=CC(Cl)=CN=C2)N=C1Cl SDKRLSAJIKWRMD-UHFFFAOYSA-N 0.000 description 1
- BDLADHWLUHMPQD-UHFFFAOYSA-N NC1=CN(C2=CC(F)=CN=C2)N=C1Cl Chemical compound NC1=CN(C2=CC(F)=CN=C2)N=C1Cl BDLADHWLUHMPQD-UHFFFAOYSA-N 0.000 description 1
- UYNXTWUYCKYSFR-UHFFFAOYSA-N O=C(CCCCl)NC1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C(CCCCl)NC1=CN(C2=CC=CN=C2)N=C1Cl UYNXTWUYCKYSFR-UHFFFAOYSA-N 0.000 description 1
- XRCFJPMAINNFCL-UHFFFAOYSA-N O=C(CCSCC1CC1(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C(CCSCC1CC1(F)F)N(CC1CC1)C1=CN(C2=CC=CN=C2)N=C1Cl XRCFJPMAINNFCL-UHFFFAOYSA-N 0.000 description 1
- MRRMNNBIBJDDKX-UHFFFAOYSA-N O=C(CCSCCC(F)(F)F)N(CC1CO1)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C(CCSCCC(F)(F)F)N(CC1CO1)C1=CN(C2=CC=CN=C2)N=C1Cl MRRMNNBIBJDDKX-UHFFFAOYSA-N 0.000 description 1
- PODZMTTVIRPETA-UHFFFAOYSA-N O=C(Cl)CCSCCC(F)(F)F Chemical compound O=C(Cl)CCSCCC(F)(F)F PODZMTTVIRPETA-UHFFFAOYSA-N 0.000 description 1
- ACWUGSRELMTOFJ-UHFFFAOYSA-N O=C(O)C=C1CCC1 Chemical compound O=C(O)C=C1CCC1 ACWUGSRELMTOFJ-UHFFFAOYSA-N 0.000 description 1
- OAIKQNRMCVPTHL-UHFFFAOYSA-N O=C(O)CC(SC1CCCC1)C(F)(F)F Chemical compound O=C(O)CC(SC1CCCC1)C(F)(F)F OAIKQNRMCVPTHL-UHFFFAOYSA-N 0.000 description 1
- CFNLMHGOXWWOQX-UHFFFAOYSA-N O=C(O)CCSCC1CC1(F)F Chemical compound O=C(O)CCSCC1CC1(F)F CFNLMHGOXWWOQX-UHFFFAOYSA-N 0.000 description 1
- KGAUNOUXSXJJRZ-UHFFFAOYSA-N O=C(O)CCSCCC(F)(F)F Chemical compound O=C(O)CCSCCC(F)(F)F KGAUNOUXSXJJRZ-UHFFFAOYSA-N 0.000 description 1
- IKXBYQKOXSAKNG-UHFFFAOYSA-N O=C1CCCN1C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C1CCCN1C1=CN(C2=CC=CN=C2)N=C1Cl IKXBYQKOXSAKNG-UHFFFAOYSA-N 0.000 description 1
- IRGMJUODSCGOFU-UHFFFAOYSA-N O=C1NCCN1C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C1NCCN1C1=CN(C2=CC=CN=C2)N=C1Cl IRGMJUODSCGOFU-UHFFFAOYSA-N 0.000 description 1
- FWVJSWJIWVWZSM-UHFFFAOYSA-N O=C1OC(CO)CN1C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound O=C1OC(CO)CN1C1=CN(C2=CC=CN=C2)N=C1Cl FWVJSWJIWVWZSM-UHFFFAOYSA-N 0.000 description 1
- PGBZSEGWWBWTBM-UHFFFAOYSA-N O=[N+]([O-])C1=CN(C2=CC=CN=C2)N=C1 Chemical compound O=[N+]([O-])C1=CN(C2=CC=CN=C2)N=C1 PGBZSEGWWBWTBM-UHFFFAOYSA-N 0.000 description 1
- LVPKVHRITJCXTQ-UHFFFAOYSA-N O=[N+]([O-])C1=CN(C2=CC=CN=C2)N=C1C1=CC=CC=C1 Chemical compound O=[N+]([O-])C1=CN(C2=CC=CN=C2)N=C1C1=CC=CC=C1 LVPKVHRITJCXTQ-UHFFFAOYSA-N 0.000 description 1
- BTKRCDYOZIOWAE-NCYHJHSESA-N [2H]C([2H])(CSC)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound [2H]C([2H])(CSC)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl BTKRCDYOZIOWAE-NCYHJHSESA-N 0.000 description 1
- CAOMCZAIALVUPA-CBTSVUPCSA-N [2H]C([2H])(CSC)C(=O)O Chemical compound [2H]C([2H])(CSC)C(=O)O CAOMCZAIALVUPA-CBTSVUPCSA-N 0.000 description 1
- LJGHYEQLQGHZJS-BMSJAHLVSA-N [2H]C([2H])([2H])SCC(C)C(=O)O Chemical compound [2H]C([2H])([2H])SCC(C)C(=O)O LJGHYEQLQGHZJS-BMSJAHLVSA-N 0.000 description 1
- OPYWMHIOONXUTL-UHFFFAOYSA-N [H]N(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound [H]N(C(=O)OC(C)(C)C)C1=CN(C2=CC=CN=C2)N=C1 OPYWMHIOONXUTL-UHFFFAOYSA-N 0.000 description 1
- LBLSSUMGXWVXFM-KGLIPLIRSA-N [H]N(C(=O)OC(C)(C)C)[C@H]1C=C[C@@H](C(=O)N(C)C2=CN(C3=CC=CN=C3)N=C2Cl)C1 Chemical compound [H]N(C(=O)OC(C)(C)C)[C@H]1C=C[C@@H](C(=O)N(C)C2=CN(C3=CC=CN=C3)N=C2Cl)C1 LBLSSUMGXWVXFM-KGLIPLIRSA-N 0.000 description 1
- NONUKDMSRBSUMC-POHAHGRESA-N [H]N(C)/C(=C/C(=O)C1=CC=CN=C1)SC Chemical compound [H]N(C)/C(=C/C(=O)C1=CC=CN=C1)SC NONUKDMSRBSUMC-POHAHGRESA-N 0.000 description 1
- FLGAAKLLJSBOEE-UHFFFAOYSA-N [H]N(C)C(C)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound [H]N(C)C(C)C(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl FLGAAKLLJSBOEE-UHFFFAOYSA-N 0.000 description 1
- LOJNHXDJCALURS-UHFFFAOYSA-N [H]N(C)C1=C(Cl)C(C2=CC=CN=C2)=NN1C Chemical compound [H]N(C)C1=C(Cl)C(C2=CC=CN=C2)=NN1C LOJNHXDJCALURS-UHFFFAOYSA-N 0.000 description 1
- LAYSAYXUNIRUQP-UHFFFAOYSA-N [H]N(C)C1=CC(C2=CC=CN=C2)=NN1C Chemical compound [H]N(C)C1=CC(C2=CC=CN=C2)=NN1C LAYSAYXUNIRUQP-UHFFFAOYSA-N 0.000 description 1
- JNHKVHFBGBGYFR-UHFFFAOYSA-N [H]N(C)C1=CN(C2=CC=CN=C2)N=C1 Chemical compound [H]N(C)C1=CN(C2=CC=CN=C2)N=C1 JNHKVHFBGBGYFR-UHFFFAOYSA-N 0.000 description 1
- LQECURWIHMMSBA-UHFFFAOYSA-N [H]N(C)CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound [H]N(C)CC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl LQECURWIHMMSBA-UHFFFAOYSA-N 0.000 description 1
- VKDYNLQHVWLPRH-UHFFFAOYSA-N [H]N(C)CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl Chemical compound [H]N(C)CCC(=O)N(CC)C1=CN(C2=CC=CN=C2)N=C1Cl VKDYNLQHVWLPRH-UHFFFAOYSA-N 0.000 description 1
- DAUKRLSROVPSQP-UHFFFAOYSA-N [H]N(C1=CN(C2=CC=CN=C2)N=C1)C(C)C Chemical compound [H]N(C1=CN(C2=CC=CN=C2)N=C1)C(C)C DAUKRLSROVPSQP-UHFFFAOYSA-N 0.000 description 1
- POHPHUCFWOUCFW-UHFFFAOYSA-N [H]N([H])C1=CN(C2=CC=CN=C2)N=C1 Chemical compound [H]N([H])C1=CN(C2=CC=CN=C2)N=C1 POHPHUCFWOUCFW-UHFFFAOYSA-N 0.000 description 1
- GRLLZAQRDYZOHG-UHFFFAOYSA-N [H]OC(=O)C(C)C(C)SC Chemical compound [H]OC(=O)C(C)C(C)SC GRLLZAQRDYZOHG-UHFFFAOYSA-N 0.000 description 1
- BSNQHVPRAPQLSW-UHFFFAOYSA-N [H]OC(=O)C1CCSC1 Chemical compound [H]OC(=O)C1CCSC1 BSNQHVPRAPQLSW-UHFFFAOYSA-N 0.000 description 1
- RTEBTDTXFFELRL-BKLSDQPFSA-N [H]OC(=O)C1C[C@@H]1SC Chemical compound [H]OC(=O)C1C[C@@H]1SC RTEBTDTXFFELRL-BKLSDQPFSA-N 0.000 description 1
- RSXSHZQENQFEHL-UHFFFAOYSA-N [H]OC(=O)CC(C)(C)SC Chemical compound [H]OC(=O)CC(C)(C)SC RSXSHZQENQFEHL-UHFFFAOYSA-N 0.000 description 1
- QWAKSOMWGWIYQP-UHFFFAOYSA-N [H]OC(=O)CC(C)SC Chemical compound [H]OC(=O)CC(C)SC QWAKSOMWGWIYQP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
- A01N57/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing heterocyclic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Definitions
- This disclosure is related to the field of processes to produce molecules that are useful as pesticides (e.g., acaricides, insecticides, molluscicides, and nematicides), such molecules, and processes of using such molecules to control pests.
- pesticides e.g., acaricides, insecticides, molluscicides, and nematicides
- Alkenyl means an acyclic, unsaturated (at least one carbon-carbon double bond), branched or unbranched, substituent consisting of carbon and hydrogen, for example, vinyl, allyl, butenyl, pentenyl, and hexenyl.
- Alkenyloxy means an alkenyl further consisting of a carbon-oxygen single bond, for example, allyloxy, butenyloxy, pentenyloxy, hexenyloxy.
- Alkoxy means an alkyl further consisting of a carbon-oxygen single bond, for example, methoxy, ethoxy, propoxy, isopropoxy, butoxy, isobutoxy, and tert-butoxy.
- Alkyl means an acyclic, saturated, branched or unbranched, substituent consisting of carbon and hydrogen, for example, methyl, ethyl, (C 3 )alkyl which represents n-propyl and isopropyl), (C 4 )alkyl which represents n-butyl, sec-butyl, isobutyl, and tert-butyl.
- Alkynyl means an acyclic, unsaturated (at least one carbon-carbon triple bond), branched or unbranched, substituent consisting of carbon and hydrogen, for example, ethynyl, propargyl, butynyl, and pentynyl.
- Alkynyloxy means an alkynyl further consisting of a carbon-oxygen single bond, for example, pentynyloxy, hexynyloxy, heptynyloxy, and octynyloxy.
- Aryl means a cyclic, aromatic substituent consisting of hydrogen and carbon, for example, phenyl, naphthyl, and biphenyl.
- (C x -C y ) where the subscripts “x” and “y” are integers such as 1, 2, or 3, means the range of carbon atoms for a substituent—for example, (C 1 -C 4 )alkyl means methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, isobutyl, and tert-butyl, each individually.
- “Cycloalkenyl” means a monocyclic or polycyclic, unsaturated (at least one carbon-carbon double bond) substituent consisting of carbon and hydrogen, for example, cyclobutenyl, cyclopentenyl, cyclohexenyl, norbornenyl, bicyclo[2.2.2]octenyl, tetrahydronaphthyl, hexahydronaphthyl, and octahydronaphthyl.
- Cycloalkenyloxy means a cycloalkenyl further consisting of a carbon-oxygen single bond, for example, cyclobutenyloxy, cyclopentenyloxy, norbornenyloxy, and bicyclo[2.2.2]octenyloxy.
- Cycloalkyl means a monocyclic or polycyclic, saturated substituent consisting of carbon and hydrogen, for example, cyclopropyl, cyclobutyl, cyclopentyl, norbornyl, bicyclo[2.2.2]octyl, and decahydronaphthyl.
- Cycloalkoxy means a cycloalkyl further consisting of a carbon-oxygen single bond, for example, cyclopropyloxy, cyclobutyloxy, cyclopentyloxy, norbornyloxy, and bicyclo[2.2.2]octyloxy.
- Halo means fluoro, chloro, bromo, and iodo.
- Haloalkoxy means an alkoxy further consisting of, from one to the maximum possible number of identical or different, halos, for example, fluoromethoxy, trifluoromethoxy, 2,2-difluoropropoxy, chloromethoxy, trichloromethoxy, 1,1,2,2-tetrafluoroethoxy, and pentafluoroethoxy.
- Haloalkyl means an alkyl further consisting of, from one to the maximum possible number of, identical or different, halos, for example, fluoromethyl, trifluoromethyl, 2,2-difluoropropyl, chloromethyl, trichloromethyl, and 1,1,2,2-tetrafluoroethyl.
- Heterocyclyl means a cyclic substituent that may be fully saturated, partially unsaturated, or fully unsaturated, where the cyclic structure contains at least one carbon and at least one heteroatom, where said heteroatom is nitrogen, sulfur, or oxygen. In the case of sulfur, that atom can be in other oxidation states such as a sulfoxide and sulfone.
- aromatic heterocyclyls include, but are not limited to, benzofuranyl, benzoisothiazolyl, benzoisoxazolyl, benzoxazolyl, benzothienyl, benzothiazolyl, cinnolinyl, furanyl, imidazolyl, indazolyl, indolyl, isoindolyl, isoquinolinyl, isothiazolyl, isoxazolyl, oxadiazolyl, oxazolinyl, oxazolyl, phthalazinyl, pyrazinyl, pyrazolinyl, pyrazolyl, pyridazinyl, pyridyl, pyrimidinyl, pyrrolyl, quinazolinyl, quinolinyl, quinoxalinyl, tetrazolyl, thiazolinyl, thiazolyl, thienyl, triaziny
- Examples of fully saturated heterocyclyls include, but are not limited to, piperazinyl, piperidinyl, morpholinyl, pyrrolidinyl, oxetanyl, tetrahydrofuranyl, tetrahydrothienyl and tetrahydropyranyl.
- Examples of partially unsaturated heterocyclyls include, but are not limited to, 1,2,3,4-tetrahydroquinolinyl, 4,5-dihydro-oxazolyl, 4,5-dihydro-1H-pyrazolyl, 4,5-dihydro-isoxazolyl, and 2,3-dihydro-[1,3,4]-oxadiazolyl. Additional examples include the following
- R1 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, S(O) n R9, S(O) n OR9, S(O
- R2 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, SR9, S(O) n OR9, or R9S(O)
- R3 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, SR9, S(O) n OR9, or R9S(O)
- R4 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, SR9, S(O) n OR9, or R9S(
- R5 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, SR9, S(O) n OR9, or R9S(O) n R9,
- R7 is O, S, NR9, or NOR9;
- R8 is substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, OR9S(O) n R9, C( ⁇ X1)R9, C( ⁇ X1)OR9, R9C( ⁇ X1)OR9, R9X2C( ⁇ X1)R9X2R9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)(R9S(O)
- R9 is (each independently) H, CN, substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, substituted or unsubstituted S(O) n C 1 -C 6 alkyl, substituted or unsubstituted N(C 1 -C 6 alkyl) 2 ,
- (k) n is 0, 1, or 2;
- X is N or CR n1 where R n1 is H, F, Cl, Br, I, CN, NO 2 , substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, OR9, C( ⁇ X1)R9, C( ⁇ X1)OR9, C( ⁇ X1)N(R9) 2 , N(R9) 2 , N(R9)C( ⁇ X1)R9, SR9, S(
- X1 is (each independently) O or S;
- X2 is (each independently) O, S, ⁇ NR9, or ⁇ NOR9;
- (O) Z is CN, NO 2 , C 1 -C 6 alkyl(R9), C( ⁇ X1)N(R9) 2 ;
- R11 is Q 1 (C ⁇ C)R12, wherein Q 1 is a bond, substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 2 -C 6 alkynyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 2 -C 10 cycloalkoxy, substituted or unsubstituted C 1 -C 6 alkylOR9, substituted or unsubstituted C 1 -C 6 alkylS(O) n R9, substituted or unsubstituted C 1 -C 6 alkylS(O) n ( ⁇ NR9), substituted or unsubstituted C 1 -C 6 alkylN(R9) (where (C ⁇ C) is attached directly to the N by a bond), substituted or unsubstituted
- R12 is Q 1 (except where Q 1 is a bond), F, Cl, Br, I, Si(R9) 3 (where each R9 is independently selected), or R9;
- A is A1.
- A is A2.
- R1 is H.
- R2 is H.
- R3 is selected from H, or substituted or unsubstituted C 1 -C 6 alkyl.
- R3 is selected from H or CH 3 .
- A1 is A11.
- R4 is selected from H, or substituted or unsubstituted C 1 -C 6 alkyl, or substituted or unsubstituted C 6 -C 20 aryl.
- R4 is selected from CH 3 , CH(CH 3 ) 2 , or phenyl.
- R4 is CH 3 .
- R4 is selected from H, or substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 6 -C 20 aryl, wherein each said R4, which is substituted, has one or more substituents selected from F, Cl, Br, or I.
- R4 is H or C 1 -C 6 alkyl.
- R4 is H, CH 3 , CH 2 CH 3 , CH ⁇ CH 2 , cyclopropyl, CH 2 Cl, CF 3 , or phenyl.
- R4 is Br or Cl.
- R5 is H, F, Cl, Br, I, or substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 1 -C 6 alkoxy.
- R5 is H, OCH 2 CH 3 , F, Cl, Br, or CH 3 .
- R6 is substituted or unsubstituted C 1 -C 6 alkyl.
- R6 is selected from is substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, C( ⁇ X1)R9, C( ⁇ X1)X2R9, R9X2R9, C( ⁇ O)(C 1 -C 6 alkyl)S(O) n (C 1 -C 6 alkyl), (C 1 -C 6 alkyl)OC( ⁇ O)(C 6 -C 20 aryl), (C 1 -C 6 alkyl)OC( ⁇ O)(C 1 -C 6 alkyl), or R9X2C( ⁇ X1)X2R9.
- R6 and R8 are connected in a cyclic arrangement, where optionally such arrangement can have one or more heteroatoms selected from O, S, or, N, in the cyclic structure connecting R6 and R8.
- R6 is C 1 -C 6 alkyl, or C 1 -C 6 alkyl-phenyl.
- R6 is H, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , CH(CH 3 ) 2 , CH 2 -phenyl, CH 2 CH(CH 3 ) 2 , CH 2 cyclopropyl, C( ⁇ O)CH 2 CH 2 SCH 3 , C( ⁇ O)OC(CH 3 ) 3 , CH 2 CH ⁇ CH 2 , C( ⁇ O)OCH 2 CH 3 , C( ⁇ O)CH(CH 3 )CH 2 SCH 3 , cyclopropyl, CD 3 , CH 2 OC( ⁇ O)phenyl, C( ⁇ O)CH 3 , C( ⁇ O)CH(CH 3 ) 2 , CH 2 C( ⁇ O)CH(CH 3 ) 2 , CH 2 C( ⁇ O)CH 3 , C( ⁇ O)phenyl, CH 2 OCH 3 , CH 2 C( ⁇ O)CH 2 OCH 2 CH 3 , CH 2 CH 2 OCH 3 , CH 2 C( ⁇ O)OCH
- R6 is methyl or ethyl.
- R7 is O or S.
- R8 is selected from substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, R9C( ⁇ X1)OR9, SR9, S(O) n OR9, R9S(O) n R9, or R9S(O) n (NZ)R9.
- R8 is CH(CH 3 )CH 2 SCH 3 , CH(CH 3 ) 2 , C(CH 3 ) 2 CH 2 SCH 3 , CH 2 CH 2 SCH 3 , CH 2 CF 3 , CH 2 CH 2 C( ⁇ O)OCH 3 , N(H)(CH 2 CH 2 SCH 3 ), OCH 2 CH 2 SCH 3 , CH(CH 2 SCH 3 )(CH 2 -phenyl), thiazolyl, oxazolyl, isothiazolyl, substituted-furanyl, CH 3 , C(CH 3 ) 3 , phenyl, CH 2 CH 2 OCH 3 , pyridyl, CH 2 CH(CH 3 )SCH 3 , OC(CH 3 ) 3 , C(CH 3 ) 2 CH 2 SCH 3 , CH(CH 3 )CH(CH 3 )SCH 3 , CH(CH 3 )CF 3 , CH 2 CH 2 -thienyl, CH(CH 3 )
- R8 is preferably R13—S(O) n —R13 wherein each R13 is independently selected from substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 2 -C 6 alkenyl, substituted or unsubstituted C 1 -C 6 alkoxy, substituted or unsubstituted C 2 -C 6 alkenyloxy, substituted or unsubstituted C 3 -C 10 cycloalkyl, substituted or unsubstituted C 3 -C 10 cycloalkenyl, substituted or unsubstituted C 6 -C 20 aryl, substituted or unsubstituted C 1 -C 20 heterocyclyl, substituted or unsubstituted S(O) n C 1 -C 6 alkyl, substituted or unsubstituted N(C 1 -C 6 alkyl) 2 , wherein each said substituted alky
- R8 is (substituted or unsubstituted C 1 -C 6 alkyl)-S(O) n -(substituted or unsubstituted C 1 -C 6 alkyl) wherein said substituents on said substituted alkyls are independently selected from F, Cl, Br, I, CN, NO 2 , C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 1 -C 6 haloalkyl, C 2 -C 6 haloalkenyl, C 1 -C 6 haloalkyloxy, C 2 -C 6 haloalkenyloxy, C 3 -C 10 cycloalkyl, C 3 -C 10 cycloalkenyl, C 3 -C 10 halocycloalkyl, C 3 -C 10 halocycloalkenyl, OC 1 -C 6 alkyl, OC 1 -C 6 haloalkyl
- R8 is selected from CH(CH 3 )SCH 2 CF 3 , CH 2 CH 2 SCH 2 CF 3 , CH 2 SCH 2 CF 3 , CH 2 SCHClCF 3 , CH(CH 2 CH 3 )SCH 2 CF 3 , CH(CH 3 )SCH 2 CHF 2 , CH(CH 3 )SCH 2 CH 2 F, CH 2 CH 2 SCH 2 CH 2 F, CH(CH 3 )S( ⁇ O) 2 CH 2 CF 3 , CH(CH 3 )S( ⁇ O)CH 2 CF 3 , CH(CH 3 )CH 2 SCF 3 , CH(CH 3 )CH 2 SCF 3 , CH(CH 3 )SCH 2 CH 2 CF 3 , and CH 2 CH 2 SCH 2 CH 2 CF 3 .
- R8 is (substituted or unsubstituted C 1 -C 6 alkyl)-S(O) n -(substituted or unsubstituted C 1 -C 6 alkyl)-(substituted or unsubstituted C 3 -C 10 cycloalkyl) wherein said substituents on said substituted alkyls and said substituted cycloalkyls are independently selected from F, Cl, Br, I, CN, NO 2 , C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 1 -C 6 haloalkyl, C 2 -C 6 haloalkenyl, C 1 -C 6 haloalkyloxy, C 2 -C 6 haloalkenyloxy, C 3 -C 10 cycloalkyl, C 3 -C 10 cycloalkenyl, C 3 -C 10 halocycloalkyl, C
- R8 is selected from CH(CH 3 )CH 2 SCH 2 (2,2 difluorocyclopropyl), CH 2 CH 2 SCH 2 (2,2 difluorocyclopropyl), CH 2 CH 2 S( ⁇ O)CH 2 (2,2 difluorocyclopropyl), CH 2 CH 2 S( ⁇ O) 2 CH 2 CH 2 (2,2 difluorocyclopropyl), and CH 2 CH(CF 3 )SCH 2 (2,2 difluorocyclopropyl).
- R8 is (substituted or unsubstituted C 1 -C 6 alkyl)-S(O) n -(substituted or unsubstituted C 2 -C 6 alkenyl) wherein said substituents on said substituted alkyls and substituted alkenyls are independently selected from F, Cl, Br, I, CN, NO 2 , C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 1 -C 6 haloalkyl, C 2 -C 6 haloalkenyl, C 1 -C 6 haloalkyloxy, C 2 -C 6 haloalkenyloxy, C 3 -C 10 cycloalkyl, C 3 -C 10 cycloalkenyl, C 3 -C 10 halocycloalkyl, C 3 -C 10 halocycloalkenyl, OC 1 -C 6 alkyl, OC 1
- R8 is selected from CH 2 CH 2 SCH 2 CH ⁇ CCl 2 , CH 2 SCH 2 CH ⁇ CCl 2 , CH(CH 3 )SCH 2 CH ⁇ CCl 2 , CH(CH 3 )SCH ⁇ CHF, CH 2 CH 2 S( ⁇ O)CH 2 CH 2 CF 3 , and CH 2 CH 2 S( ⁇ O) 2 CH 2 CH 2 CF 3 .
- X is CR n1 where R n1 is H or halo.
- X is CR n1 where R n1 is H or F.
- X1 is O.
- X2 is O.
- R11 is substituted or unsubstituted C 1 -C 6 alkylC ⁇ CR12.
- R11 is CH 2 C ⁇ CH.
- the molecules of Formula One will generally have a molecular mass of about 100 Daltons to about 1200 Daltons. However, it is generally preferred if the molecular mass is from about 120 Daltons to about 900 Daltons, and it is even more generally preferred if the molecular mass is from about 140 Daltons to about 600 Daltons.
- step a of Scheme I treatment of a 3-acetopyridine or a 5-acetopyrimidine of Formula II, wherein R1, R2, R3 and X are as previously defined, with carbon disulfide and iodomethane in the presence of a base such as sodium hydride and in a solvent such as dimethyl sulfoxide provides the compound of Formula III.
- step b of Scheme I the compound of Formula III can be treated with an amine or amine hydrochloride, in the presence of a base, such as triethylamine, in a solvent such as ethyl alcohol to afford the compound of Formula IV, wherein R1, R2, R3, R6 and X are as previously defined.
- a hydrazine such as methylhydrazine
- a polar protic solvent such as ethyl alcohol.
- a boronic acid such as phenylboronic acid
- a catalyst such as palladium tetrakis
- a base such as 2M aqueous potassium carbonate
- a mixed solvent system such as ethanol and toluene
- a reducing agent such as sodium borohydride
- a polar protic solvent such as ethanol
- the compounds of Formula XIIb can be acylated with an acid chloride such as acetyl chloride in a polar aprotic solvent such as dichloromethane using the conditions described in Scheme V.
- the compounds of Formula XIIb can be treated with benzotriazole and an aldehyde in ethanol followed by reduction using, for example, sodium borohydride, to afford compounds of Formula XIIIa.
- acylation of compounds of Formula XIIIa in Scheme IV using the conditions described in Scheme IX affords compounds of Formula Ia, wherein R1, R2, R3, R4, R5, R6, R8 and X are as previously defined.
- step a of Scheme V the compounds of Formula Vc, wherein R1, R2, R3, R4, R5 and R6 and X are as previously defined, can be treated with an acid chloride of Formula XIV, in the presence of a base such as triethylamine or N,N-dimethylaminopyridine in a polar aprotic solvent such as dichloroethane (DCE) to yield compounds of Formula Ib, wherein R8 is as previously defined.
- a base such as triethylamine or N,N-dimethylaminopyridine
- a polar aprotic solvent such as dichloroethane (DCE)
- the 2° amide may be subsequently alkylated in step b of Scheme V with an alkyl halide such as iodoethane, in the presence of a base such as sodium hydride and a polar aprotic solvent such as N,N-dimethylformamide (DMF) to yield the desired compounds of Formula Ib.
- an alkyl halide such as iodoethane
- a base such as sodium hydride
- a polar aprotic solvent such as N,N-dimethylformamide (DMF)
- a halogen source such as N-chlorosuccinimide or N-bromosuccinimide
- a polar aprotic solvent such as acetonitrile
- ureas and carbamates are made from the aminopyrazoles of Formula Ve.
- Compounds of Formula Ve, wherein X, R1, R2, R3, R4, R5 and R6 are as previously defined are allowed to react with phosgene to provide the intermediate carbamoyl chloride which is subsequently treated with an amine, as shown in step b, or alcohol, as shown in step c, respectively, to generate a urea of Formula Id or a carbamate of Formula Ie, respectively, wherein R9 is as previously defined.
- step a of Scheme VIII compounds of Formula XIIc, wherein X, R1, R2, R3, R4 and R5 are as previously defined, can be treated with di-tert-butyl dicarbonate (Boc 2 O) and a base such as triethylamine in a polar aprotic solvent such as dichloromethane (DCM) to yield compounds of Formula XVIa.
- a polar aprotic solvent such as dichloromethane (DCM)
- compounds of Formula XIIIc can be converted to compounds of Formula Id in the presence of a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl) and a base such as N,N-dimethylaminopyridine (DMAP) in a polar aprotic solvent such as dichloroethane (DCE), as shown in step a.
- a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl) and a base such as N,N-dimethylaminopyridine (DMAP) in a polar aprotic solvent such as dichloroethane (DCE), as shown in step a.
- a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- compounds of Formula XIIIc can be converted to compounds of Formula Id in the presence of 2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine in a polar aprotic solvent such as 1,4-dioxane under elevated temperature, as shown in step b.
- a polar aprotic solvent such as 1,4-dioxane under elevated temperature
- compounds of Formula XIIIc can be converted to compounds of Formula Id in a polar aprotic solvent such as dichloromethane (DCM), as shown in step c.
- DCM dichloromethane
- a thionating agent
- step a of Scheme X compounds of Formula XIIId, wherein X, R1, R2, R3, R4, R5 and R6 are as previously defined, can be treated with compounds of Formula XIX, wherein R8 is as previously defined, in a polar aprotic solvent such as dichloroethane (DCE) to yield compounds of Formula XX.
- a polar aprotic solvent such as dichloroethane (DCE)
- DCE dichloroethane
- compounds of Formula XX can be treated with a base, such as sodium hydride, in a polar aprotic solvent, such as THF, to yield compounds of Formula XXI, where m is an integer selected from 1, 2, 3, 4, 5, or 6, as shown in step b of Scheme X.
- the sulfide of Formula XXIIa can be oxidized with an oxidant such as hydrogen peroxide in a polar protic solvent such as hexafluoroisopropanol to give the sulfoxide of Formula XXIII as in step d of Scheme XI.
- the sulfoxide of Formula XXIII can be further oxidized to the sulfone of Formula XXIV by sodium perborate tetrahydrate in a polar protic solvent such as glacial acetic acid as in step c of Scheme XI.
- the sulfone of Formula XXIV can be generated in a one-step procedure from the sulfide of Formula XXIIa by using the aforementioned conditions with >2 equivalents of sodium perborate tetrahydrate, as in step b of Scheme XI.
- the sulfilimine of Formula XXV may be further oxidized to the sulfoximine of Formula XXVI with an oxidant such as meta-Chloroperoxybenzoic acid (“mCPBA”) in the presence of a base such as potassium carbonate in a protic polar solvent system such as ethanol and water as in step b of Scheme XII.
- an oxidant such as meta-Chloroperoxybenzoic acid (“mCPBA”) in the presence of a base such as potassium carbonate in a protic polar solvent system such as ethanol and water as in step b of Scheme XII.
- aminopyrazoles of Formula XIIIe can be prepared from iodopyrazoles of Formula XXVII through cross coupling reactions with an appropriate amine in the presence of a base such as cesium carbonate, a copper catalyst such as copper (I) bromide, and a ligand such as 1-(5,6,7,8-tetrahydroquinolin-8-yl)ethanone in a polar aprotic solvent such as DMSO.
- a base such as cesium carbonate
- a copper catalyst such as copper (I) bromide
- a ligand such as 1-(5,6,7,8-tetrahydroquinolin-8-yl)ethanone in a polar aprotic solvent such as DMSO.
- step a of the Scheme XIV compounds of the formula XXIX, wherein R4 is Cl, R5 is H and X ⁇ represents Cl ⁇ , can be prepared according to the methods described in Acta. Pharm. Suec. 22, 147-156 (1985) by Tolf, Bo-Ragnar and Dahlbom, R.
- compounds of the Formula XXIX, wherein R4 is Br, X ⁇ represents Br ⁇ and R5 is as defined previously can be prepared by treating compounds of the Formula XXVIII with hydrogen gas in the presence of a metal catalyst such as 5% Pd on alumina and a solution of 50% aqueous HBr in a solvent such as ethanol.
- step a of Scheme XIV compounds of the Formula XXIX, wherein R4 is Cl or Br, X ⁇ represents Cl ⁇ or Br ⁇ and R5 is as defined previously, can be prepared by treating compounds of the Formula XXVIII, wherein R5 is as defined previously, with a hydrosilane such as triethyl silane in the presence of a metal catalyst such as 5% Pd on alumina and an acid such as HCl or HBr, respectively, in a solvent such as ethanol.
- a hydrosilane such as triethyl silane
- a metal catalyst such as 5% Pd on alumina
- an acid such as HCl or HBr
- step b of the Scheme XIV compounds of the Formula XXX, wherein R4 is Cl or Br and R5 is as defined previously, can be prepared by treating the compounds of the Formula XXIX, wherein R4 is Cl or Br, X ⁇ represents CF or Br ⁇ and R5 is as defined previously, with di-tert-butyl dicarbonate (Boc 2 O) in the presence of a mixture of solvents such as THF and water and a base such as sodium bicarbonate.
- a mixture of solvents such as THF and water
- a base such as sodium bicarbonate
- step c of the Scheme XIV compounds of the Formula XVIa, wherein X, R1, R2, R3 and R5 are as defined previously and R4 is Cl or Br, preferably Cl can be obtained by treating compounds of the Formula XXX, wherein R4 is Cl or Br and R5 is as defined previously, preferably H, with compounds of the Formula VIIIb, wherein X, R1, R2 and R3 are as defined previously and Q is iodo, in the presence of a catalytic amount of copper salt such as CuCl 2 , a ligand such as an ethane-1,2-diamine derivative such as N 1 ,N 2 -dimethylethane-1,2-diamine and a base such as K 3 PO 4 in a polar aprotic solvent such as acetonitrile at a suitable temperature.
- a catalytic amount of copper salt such as CuCl 2
- a ligand such as an ethane-1,2-diamine derivative such as N 1 ,
- step c pyrazoles of Formula XXX are coupled with compounds of the Formula VIIIb, preferably 3-iodo pyridine, in the presence of a metal catalyst, such as CuCl 2 , and a diamine ligand such as N 1 ,N 2 -dimethylethane-1,2-diamine, and an inorganic base, such as K 3 PO 4 .
- a metal catalyst such as CuCl 2
- a diamine ligand such as N 1 ,N 2 -dimethylethane-1,2-diamine
- an inorganic base such as K 3 PO 4
- the reaction is carried out in a polar aprotic solvent such as acetonitrile.
- the reaction is conducted at a temperature from about 60° C. to about 82° C. and preferably from about 75° C. to 82° C.
- a 1:1.2 molar ratio of pyrazoles of Formula XXX to heterocyclyl iodide of Formula VIIIb may be used, however, a molar ratios of about 5:1 to about 1:5 may also be used.
- the reaction is conducted at about atmospheric pressure, however, higher or lower pressures can be used.
- Boc-group of compounds of Formula XVIa can be removed under conditions that are well-known in the art such as under acidic conditions such as TFA in a polar aprotic solvent such as dichloromethane to give compounds of Formula XIId, as shown in step d of Scheme XIV.
- Bromopyrazoles of Formula XXXI wherein R1, R2, R3, R5, R8 and X are as previously defined, can be allowed to react under Suzuki coupling conditions with a boronic ester such as vinylboronic acid pinacol ester or cyclopropylboronic acid pinacol ester in the presence of a catalyst such as palladium tetrakis, a base such as 2 M aqueous potassium carbonate, and in a mixed solvent system such as ethanol and toluene to provide compounds of Formula XXXII, as shown in step a of Scheme XV.
- a boronic ester such as vinylboronic acid pinacol ester or cyclopropylboronic acid pinacol ester
- a catalyst such as palladium tetrakis
- a base such as 2 M aqueous potassium carbonate
- a mixed solvent system such as ethanol and toluene
- the vinyl group of compounds of Formula XXXIII can be reduced in the presence of hydrogen with a catalyst such as 10% Pd/C in a polar protic solvent such methanol to give compounds of Formula XXXIV, as shown in step a of Scheme XVI.
- a catalyst such as 10% Pd/C in a polar protic solvent such methanol
- Oxidation of the vinyl group of compounds of Formula XXXIII using an oxidant such as osmium tetroxide in the presence of sodium periodate in mixture of a polar protic solvent such as water and a polar aprotic solvent such as THF gave compounds of Formula XXXV, as shown in step b of Scheme XVI.
- an ⁇ , ⁇ -unsaturated acid XXXVIII can be treated with a nucleophile such as sodium thiomethoxide in a polar protic solvent such as methanol to give acid XXXIX.
- a nucleophile such as sodium thiomethoxide
- a polar protic solvent such as methanol
- a reagent such as propargyl bromide
- step a of Scheme XIX compounds of Formula XL, wherein X, R1, R2, R3, R4, R5 and R6 are as previously defined, can be treated with an acid of Formula XLI, wherein R8 is as previously defined, in the presence of a coupling reagent, such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl), and a base, such as N,N-dimethylaminopyridine (DMAP), in a polar aprotic solvent, such as dichloromethane (DCM), to yield compounds of Formula XLII.
- a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl)
- EDC.HCl 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
- DMAP N,
- step b compounds of the Formula XLII can be treated with a base, such as sodium methoxide, in a polar solvent such as THF, followed by an alkyl halide R9-Hal to give the compounds of the Formula XLIII.
- a base such as sodium methoxide
- a polar solvent such as THF
- step a of Scheme XX compounds of the Formula XL or the corresponding HCl salt, wherein X, R1, R2, R3, R4, R5, and R6 are as previously defined, can be coupled to acids of the formula XLIV, wherein R8 is as previously defined, in the presence of a coupling reagent, such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.
- a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.
- step b of Scheme XX compounds of the Formula XLV, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined and Tr represents trityl (triphenylmethyl), can be treated with an acid, such as 2,2,2-trifluoroacetic acid, in the presence of a trialkyl silane, such as triethyl silane, in a polar aprotic solvent, such as methylene chloride, to remove the trityl group to give thiols of the Formula XLVI, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined.
- an acid such as 2,2,2-trifluoroacetic acid
- a trialkyl silane such as triethyl silane
- a polar aprotic solvent such as methylene chloride
- thiols of the Formula XLVI can be treated with a base, such as sodium hydride, in a polar aprotic solvent such as tetrahydrofuran, or cesium carbonate in acetonitrile, or DBU in dimethylformamide, and an electrophile (R9-Hal), such as 2-(bromomethyl)-1,1-difluorocyclopropane, in tetrahydrofuran, to give compounds of the Formula XLVII.
- a base such as sodium hydride
- a polar aprotic solvent such as tetrahydrofuran, or cesium carbonate in acetonitrile, or DBU in dimethylformamide
- R9-Hal electrophile
- 2-(bromomethyl)-1,1-difluorocyclopropane in tetrahydrofuran
- step a of the Scheme XXI compounds of the Formula XL or the corresponding HCl salt, wherein X, R1, R2, R3, R4, R5, and R6 are as previously defined, can be coupled to acids of the Formula XLVIII, wherein R9 is as previously defined, in the presence of a coupling reagent such as EDC.HCl and a base such as DMAP in a polar aprotic solvent such as DMF to yield compounds of Formula XLIX, where in X, R1, R2, R3, R4, R5, R6 and R9 are as previously defined.
- a coupling reagent such as EDC.HCl and a base such as DMAP
- a polar aprotic solvent such as DMF
- step b of the Scheme XXI compounds of the Formula XLIX, wherein X, R1, R2, R3, R4, R5, R6 and R9 are as previously defined, can be treated with a thio acid salt, such as potassium thioacetate, at an elevated temperature (about 50° C.) in a solvent, such as DMSO, to give compounds of the Formula L, wherein X, R1, R2, R3, R4, R5, R6 and R9 are as previously defined.
- a thio acid salt such as potassium thioacetate
- step c of the Scheme XXI compounds of the Formula L, wherein X, R1, R2, R3, R4, R5, R6 and R9 are as previously defined, can be treated with an equimolar amount of a base, such as sodium methoxide, prepared from mixing sodium hydride, and methanol, followed by an electrophile (R9-Halo), such as 2-(bromomethyl)-1,1-difluorocyclopropane, in a solvent, such as tetrahydrofuran, to give compounds of the Formula LI.
- a base such as sodium methoxide
- R9-Halo an electrophile
- step a of Scheme XXII compounds of the Formula XL, wherein X, R1, R2, R3, R4, R5, R6, and halo are as previously defined, can be treated with an acid chloride of Formula LII in the presence of a base, such as triethylamine or diisopropylethylamine in a polar aprotic solvent, such as DCE, to yield compounds of the Formula LII, wherein R8 is either a substituted or unsubstituted alkyl chain.
- a base such as triethylamine or diisopropylethylamine
- a polar aprotic solvent such as DCE
- a one-pot methanolysis/alkylation sequence can be achieved via treatment of compounds of the Formula LIV with one equivalent of a base, such as sodium methoxide (NaOMe) in a polar aprotic solvent, such as tetrahydrofuran (THF).
- a base such as sodium methoxide (NaOMe)
- a polar aprotic solvent such as tetrahydrofuran (THF).
- An alkyl sulfonate or alkyl halide such as 2-iodo-1,1,1-trifluoroethane, can then be added to the reaction mixture to deliver compounds of the Formula LV, wherein R9 is as previously defined.
- compounds of the Formula LV may be obtained from compounds of the Formula LIII via treatment with an alkyl thiol such as 2,2,2-trifluoroethanethiol at elevated temperatures (about 50° C.) in a polar aprotic solvent, such as THF, in the presence of sodium iodide and a base, such as diisopropylethylamine.
- a polar aprotic solvent such as THF
- a base such as diisopropylethylamine
- step f treating compounds of Formula LIII with an alkyl thiol, such as sodium methanethiolate, in a polar aprotic solvent, such as DMSO, at elevated temperatures (about 50° C.) will afford compounds of Formula LV.
- step e when compounds of the Formula LIV are treated with two or more equivalents of a base, such as NaOMe, followed by a 1,2,2-trihaloalkyl compound, such as 2-bromo-1,1-difluoroethane, compounds of Formula LVI are obtained.
- a base such as NaOMe
- a 1,2,2-trihaloalkyl compound such as 2-bromo-1,1-difluoroethane
- step a of Scheme 23 compounds of Formula 23.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, can be treated with a base, such as aqueous 2M lithium hydroxide, in a polar protic solvent, such as methanol, to give compounds of Formula 23.2.
- a base such as aqueous 2M lithium hydroxide
- a polar protic solvent such as methanol
- a base such as sodium hydride
- a polar aprotic solvent such as tetrahydrofuran (THF)
- step b of Scheme 24 compounds of Formula 24.2 can be treated with a base, such as triethylamine, and silylation reagents, such as trimethylsilyl trifluoromethanesulfonate and dimethylmethylideneammonium iodide (Eschenmoser's salt) in a polar aprotic solvent, such as dichloromethane (DCM), to yield compounds of Formula 24.3.
- a base such as triethylamine
- silylation reagents such as trimethylsilyl trifluoromethanesulfonate and dimethylmethylideneammonium iodide (Eschenmoser's salt)
- DCM dichloromethane
- step c of Scheme 24 compounds of Formula 24.3 can be treated with a base, such as potassium hydroxide, and a nucleophile, such as S,S-dimethyl carbonodithioate, in water and a polar aprotic solvent such as tetrahydrofuran (THF) to yield compounds of Formula 24.4, wherein X, R1, R2, R3, R4, R5, R9 and m are as previously defined.
- a base such as potassium hydroxide
- a nucleophile such as S,S-dimethyl carbonodithioate
- step a when compounds of the Formula 25.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, are treated with two or more equivalents of a base, such as sodium methoxide, followed by a 1,2-dihaloalkyl compound, such as 1-fluoro-2-iodoethane, in a solvent, such as tetrahydrofuran (THF), compounds of Formula 25.2, wherein R9 is as previously defined, are obtained.
- a base such as sodium methoxide
- a 1,2-dihaloalkyl compound such as 1-fluoro-2-iodoethane
- a solvent such as tetrahydrofuran (THF)
- step a of Scheme 26 An alternative route to vinyl sulfides is described in step a of Scheme 26.
- This route utilizes conditions developed by Kao and Lee ( Org. Lett. 2011, 13, 5204-5207) in which thiols of the Formula 26.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, are coupled with a vinyl halide, such as (E)-1-bromo-3,3,3-trifluoroprop-1-ene, in the presence of a catalyst, such as copper(I) oxide, a base, such as potassium hydroxide, and a solvent, such as dioxane, at elevated temperatures to afford products of Formula 26.2, wherein R9 is as previously defined.
- a catalyst such as copper(I) oxide
- a base such as potassium hydroxide
- solvent such as dioxane
- step a of Scheme 27 an acrylamide of Formula 27.1, wherein X, R1, R2, R3, R4, R5, and R6 are as previously defined, is reacted with a sulfonamide of Formula 27.2, wherein R9 is as previously defined, in the presence of a base, such as potassium carbonate, at elevated temperatures in a polar aprotic solvent, such as dimethylformamide (DMF), to deliver compounds of Formula 27.3.
- a base such as sodium hydride
- an alkyl halide such as 2-bromoacetonitrile
- a polar aprotic solvent such as tetrahydrofuran (THF)
- Compounds of the Formula 28.3 may be treated with a sulfonyl chloride, such as methanesulfonyl chloride, in the presence of a base, such as diisopropylethylamine, and a polar aprotic solvent, such as dichloromethane (DCM), to afford products of the Formula 28.4, as shown in step b.
- a sulfonyl chloride such as methanesulfonyl chloride
- a base such as diisopropylethylamine
- a polar aprotic solvent such as dichloromethane (DCM)
- compounds of Formula 28.3 may be prepared via a two step process as described in steps d and e of Scheme 28.
- Compounds of Formula 28.6 can be converted to compounds of Formula 28.8 when treated with compounds of Formula 28.7 in the presence of a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl) and a base such as N,N-dimethylaminopyridine (DMAP) in a polar aprotic solvent such as dichloroethane (DCE), as shown in step d.
- a coupling reagent such as 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl) and a base such as N,N-dimethylaminopyridine (DMAP) in a polar aprotic solvent such as dichloroethane (DCE), as shown in step d
- the Boc-group can be removed under conditions that are well-known in the art, such as under acidic conditions such as trifluoroacetic acid (TFA) in a polar aprotic solvent like dichloromethane to give compounds of Formula 28.3 as in step e.
- acidic conditions such as trifluoroacetic acid (TFA) in a polar aprotic solvent like dichloromethane to give compounds of Formula 28.3 as in step e.
- step a of Scheme 29 compounds of Formula 29.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, can be reacted with either a cyclic or acyclic enone, such as but-3-ene-2-one, under the conditions described by Chakraborti ( Org. Lett. 2006, 8, 2433-2436) to deliver compounds of the Formula 29.2, wherein R9 is as previously defined.
- a fluorinating reagent such as Deoxo-Fluor®
- an initiator such as ethanol
- a polar aprotic solvent such as dichloromethane (DCM)
- Step a of Scheme 30 depicts the hydrolysis of compounds of the Formula 30.1, wherein X, R1, R2, R3, R4, R5, R6, R8, and R9 are as previously defined, via treatment with an acid, such as aqueous hydrochloric acid, in a solvent, such as THF, to afford an intermediate aldehyde of the Formula 30.2.
- Compounds of the Formula 30.2 can be immediately reacted with a fluorinating reagent, such as Deoxo-Fluor®, in the presence of an initiator, such as ethanol, and a solvent, such as tetrahydrofuran (THF), to provide products of the Formula 30.3.
- a fluorinating reagent such as Deoxo-Fluor®
- a one-pot deprotection/alkylation sequence can be achieved via treatment of compounds of the Formula 31.3 with one equivalent of a base, such as sodium methoxide (NaOMe), in a polar aprotic solvent, such as tetrahydrofuran (THF).
- a base such as sodium methoxide (NaOMe)
- a polar aprotic solvent such as tetrahydrofuran (THF).
- a compound of the Formula 31.4 wherein X, R1, R2, R3, R4, R5, R6, R8 and halo are as previously defined, may then be added to the reaction mixture to afford compounds of the Formula 31.5.
- a neat mixture of an olefin of the Formula 32.1, where n is an integer selected from 0, 1, 2, 3, 4, or 5, and trimethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate can be heated in the presence of sodium fluoride to deliver a substituted difluorocyclopropane of the Formula 32.2, as indicated in step a.
- this product was treated with tetrabutylammonium fluoride (TBAF) in tetrahydrofuran (THF) to afford an intermediate homoallylic alcohol of the Formula 32.3.
- TBAF tetrabutylammonium fluoride
- THF tetrahydrofuran
- This alcohol was not isolated, but rather immediately treated with p-toluenesulfonyl chloride in the presence of pyridine and dichloromethane to afford a tosylate of the Formula 32.4, as shown in step c.
- amines of Formula 33.1 are coupled with acid chlorides of Formula 33.2 in the presence of a base, or combination of bases such as pyridine, N,N-dimethylaminopyridine, or diisopropylethylamine.
- the reaction is carried out in a halogenated solvent such as 1,2-dichloroethane or methylene chloride.
- the reaction is conducted at a temperature from 0° C. to 80° C. and preferably from about 0° C. to 23° C.
- a 1:1 molar ratio of the amine of formula 33.1 to acid chloride of Formula 33.2 may be used, however, molar ratios of about 5:1 to about 1:5 may also be used.
- the reaction is conducted at about atmospheric pressure, however, higher or lower pressures can be used.
- step a of Scheme 34 the compounds of Formula 34.1, wherein R1, R2, R3, R4, R5 and R6 and X are as previously defined, can be treated with an acid of Formula 34.2, wherein R8 is as previously defined, in the presence of N,N′-dicyclohexylcarbodiimide (DCC), and a base, such as N,N-dimethylaminopyridine (DMAP), in a solvent, such as diethyl ether (Et 2 O), to yield compounds of Formula 34.3.
- DCC N,N′-dicyclohexylcarbodiimide
- DMAP N,N-dimethylaminopyridine
- Et 2 O diethyl ether
- step a of Scheme 35 aminopyrazoles of Formula 35.1, wherein X, R1, R2, R3, R4, R5 and R6 are as previously defined, can be treated with phosgene and N,N-dimethylaminopyridine (DMAP) at about 80° C. in a polar aprotic solvent such as dichloroethane (DCE).
- DMAP N,N-dimethylaminopyridine
- a polar aprotic solvent such as dichloroethane (DCE).
- DMAP N,N-dimethylaminopyridine
- DCE dichloroethane
- step d treatment with an amine, as shown in step b, or an alcohol, as shown in step c, or a thiol, as shown in step d, generates a urea of Formula 35.2, a carbamate of Formula 35.3, or a carbamothioate of Formula 35.4, wherein R9 is as previously defined, respectively.
- step a of Scheme 36 compounds of Formula 36.1, wherein X, R1, R2 and R3 are as previously defined, can be treated with a base such as triethylamine, carbon disulfide and a sulfonyl chloride such as 4-methylbenzene-1-sulfonyl chloride in a polar aprotic solvent such as tetrahydrofuran (THF) to yield compounds of Formula 36.2.
- oxazolidin-2-one can be treated with an equimolar amount of a base, such as sodium hydride followed by compounds of Formula 36.2, in a polar aprotic solvent such as dimethylformamide (DMF) to give compounds of the Formula 36.3.
- the product of step b, (previous to work-up) can be treated with an electrophile such as iodomethane to give compounds of Formula 36.4 as demonstrated in step c of Scheme 36.
- ureas of Formula 37.1 wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined, can be reacted with a base such as lithium bis(trimethylsilyl)amide in a polar aprotic solvent such as THF followed by an acyl chloride such as pivaloyl chloride to yield acylated ureas of Formula 37.2, wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined.
- a base such as lithium bis(trimethylsilyl)amide
- a polar aprotic solvent such as THF
- an acyl chloride such as pivaloyl chloride
- ureas of Formula 37.1 wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined, can be reacted with a base such as lithium bis(trimethylsilyl)amide in a polar aprotic solvent such as THF followed by an alkyl halide such as (chloromethyl)(methyl)sulfane to yield alkylated ureas of Formula 37.2, wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined.
- a base such as lithium bis(trimethylsilyl)amide
- a polar aprotic solvent such as THF
- an alkyl halide such as (chloromethyl)(methyl)sulfane
- ureas of Formula 37.1 wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined, can be reacted with a base such as lithium bis(trimethylsilyl)amide in a polar aprotic solvent such as THF followed by a sulfonyl chloride such as methanesulfonyl chloride to yield sulfonylated ureas of Formula 37.3, wherein R1, R2, R3, R4, R5, R6, R8, and X are as previously defined.
- a base such as lithium bis(trimethylsilyl)amide
- a polar aprotic solvent such as THF
- a sulfonyl chloride such as methanesulfonyl chloride
- amines of Formula 38.1 wherein R6 is H or Me, can be reacted with an electrophile of Formula 38.2, wherein R8 and R9 are as previously defined, such as naphthalen-2-ylmethyl 3-(methylthio)propanimidothioate hydrobromide in a polar protic solvent such as ethanol followed by exposure to a base such as MP-Carbonate in a polar protic solvent such as methanol to give amidines of Formula 38.3, wherein R6 is H or Me, and R8 and R9 are as previously defined.
- step a of the Scheme 39 compounds of the Formula 39.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, can be treated with alcohols of the Formula 39.2, wherein R9 is as previously defined, in the presence of a base such as sodium hydride or potassium tert-butoxide in a polar aprotic solvent such as THF at appropriate temperatures, to give the corresponding ethers of the Formula 39.3.
- a base such as sodium hydride or potassium tert-butoxide
- a polar aprotic solvent such as THF
- thioethers of the Formula 39.5 can be obtained by treating compounds of the Formula 39.1, wherein X, R1, R2, R3, R4, R5, R6 and R8 are as previously defined, with thiols of the Formula 39.4, wherein R9 is as previously defined, in the presence of a base such as sodium hydride in an aprotic solvent such as THF.
- step a of Scheme 41 compounds of the Formula 41.1, wherein X, R1, R2, R3, R4, R5 and R6 are as previously defined, can be coupled to acids of the Formula 41.2, wherein R8 and R9 are as previously defined, in the presence of a coupling reagent such as EDC.HCl and a base such as DMAP in an aprotic solvent such as dichloromethane to give phosphonates of the Formula 41.3.
- a coupling reagent such as EDC.HCl and a base such as DMAP
- an aprotic solvent such as dichloromethane
- step b of Scheme 41 phosphonates of the Formula 41.3, wherein X, R1, R2, R3, R4, R5, R6, R8 and R9 are as previously defined, can be treated with carbonyl compounds of the Formula 41.4, where R9 is as previously defined in the presence of a base such as sodium hydride in an aprotic solvent such as THF to give the corresponding alkenes of the Formula 41.5.
- a base such as sodium hydride
- an aprotic solvent such as THF
- step a of the Scheme 42 compounds of the Formula 42.1, wherein X, R1, R2, R3, R4, and R5, are as previously defined, can be treated with trifluoroacetic anhydride in the presence of a base such as triethylamine in an aprotic solvent such as dichloromethane to give amides of the Formula 42.2, where X, R1, R2, R3, R4, and R5, are as previously defined.
- amides of the Formula 42.2 wherein X, R1, R2, R3, R4, and R5, are as previously defined, can be treated with an alkylating agent such as iodomethane in the presence of a base such as potassium tert-butoxide in a solvent such as THF to afford compounds of the Formula 42.3.
- a base such as potassium tert-butoxide
- a solvent such as THF
- amides of the Formula 42.3, wherein X, R1, R2, R3, R4, and R5, are as previously defined can be treated under basic conditions such as potassium carbonate and methanol to give the corresponding amines of the Formula 42.4.
- Step 3 Preparation of methyl-(2-methyl-5-pyridin-3-pyrazol-3-yl)-amine
- N-ethyl-1-methyl-3-(pyridin-3-yl)-1H-pyrazol-5-amine was prepared as described in Example 1, Step 3: ESIMS m/z 203 ([M+H]).
- N-methyl-1-phenyl-3-(pyridin-3-yl)-1H-pyrazol-5-amine was prepared as described in Example 1, Step 3: ESIMS m/z 252 ([M+2H]).
- N-(cyclopropylmethyl)-1-methyl-3-(pyridin-3-yl)-1H-pyrazol-5-amine was prepared as described in Example 1, Step 3: ESIMS m/z 230 ([M+2H]).
- Compound 8 was made in accordance with the procedures disclosed in Example 4 using 2-(methylthio)ethanol in place of 2-methylthioethylamine.
- Compound 22 was prepared in accordance with the procedures disclosed in Example 15.
- the reaction which started to slowly exotherm from 35° C. to 55° C. over 2.0 h, was stirred for a total of 16 h and vacuum filtered through a plug of Celite® to give a biphasic mixture.
- the mixture was transferred to a separatory funnel, the bottom aqueous layer was collected and rotary evaporated (60° C., 50 mmHg) to dryness with the aid of acetonitrile (3 ⁇ 350 mL).
- the resulting yellow solid was suspended in acetonitrile (150 mL) and allowed to stand for 2 h at room temperature followed by 1 h at 0° C. in the refrigerator.
- the phases were separated collecting the white gelatinous precipitate and the aqueous layer together.
- the aqueous was extracted with ethyl acetate (2 ⁇ 200 mL) and the ethyl acetate extracts were combined, washed with brine (200 mL), dried over anhydrous sodium sulfate, filtered and rotary evaporated to give an auburn thick oil (160 g.).
- the thick oil was suspended in hexane (1000 mL) and stirred at 55° C. for 2 h. This gave a light brown suspension.
- the mixture was cooled to 0° C. and the solid collected by vacuum filtration and rinsed with hexane (2 ⁇ 10 mL).
- the mixture was cooled to room temperature and filtered through a bed of Celite®.
- the filtrate was transferred to a 4 L Erlenmeyer flask equipped with mechanical stirrer and diluted with water until the total volume was about 4 L.
- the mixture was stirred for 30 minutes at room temperature and the resulting solid was collected by vacuum filtration.
- the solid was washed with water and washed with water and oven dried for several days in vacuo at 40° C.
- Compound 172 was also prepared in accordance with the procedures disclosed in Example 13.
- Compound 317 was prepared in accordance with the procedures disclosed in Example 17 from tert-butyl (3-bromo-1H-pyrazol-4-yl)carbamate and also in accordance with the procedures disclosed in Example 13.
- HCl 3-Bromo-N-methyl-1-(pyridin-3-yl)-1H-pyrazol-4-amine, HCl was prepared as described in Example 26 from tert-butyl (3-bromo-1-(pyridin-3-yl)-1H-pyrazol-4-yl)(methyl)carbamate (160 mg, 0.45 mmol) in dioxane (1 mL) was added 4M HCl: mp.
- tert-butyl (3-cyclopropyl-1-(5-fluoropyridin-3-yl)-1H-pyrazol-4-yl)carbamate (705 mg, 2.215 mmol, 71.9% yield) as a yellow solid
- tert-butyl (1-(5-fluoropyridin-3-yl)-1H-pyrazol-4-yl)carbamate (242 mg, 0.870 mmol, 28.2% yield) as a yellow solid.
- Compound 369 was prepared in accordance with the procedures disclosed in Example 35.
- Compound 349 was prepared in accordance with the procedures disclosed in Example 47.
- Step 1 Preparation of N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-2-methyl-3-(methylthio)propanamide
- Step 2 Preparation of N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-(2-hydroxyethyl)-2-methyl-3-(methylthio)propanamide (Compound 535)
- Triethylamine (5.57 mL, 40.00 mmol) and methanesulfonyl chloride (2.85 mL, 36.60 mmol) were sequentially added to a stirred solution of ethyl 1-(hydroxymethyl)cyclopropanecarboxylate (4.80 g, 33.30 mmol) in dichloromethane (83 mL) at 23° C.
- the resulting bright yellow solution was stirred at 23° C. for 20 h.
- the reaction mixture was diluted with water and extracted with dichloromethane.
- 2,2-Dimethyl-3-(methylthio)propanoic acid can be prepared as demonstrated in the literature (reference Musker, W. K.; et al. J. Org. Chem. 1996, 51, 1026-1029).
- Sodium methanethiolate 1.0 g, 14 mmol, 2.0 equiv
- 3-chloro-2,2-dimethylpropanoic acid 1.0 g, 7.2 mmol, 1.0 equiv
- N,N-dimethylformamide 3.0° C.
- the resulting brown suspension was allowed to warm to 23° C. and stirred for 24 h.
- Tetrahydro-thiophene-3-carboxylic acid was made using the procedures disclosed in Heterocycles, 2007, 74, 397-409.
- N,N-dimethylpyridin-4-amine (2.60 g, 21.31 mmol)
- 2-methyl-3-(tritylthio)propanoic acid (4.41 g, 12.18 mmol)
- N1-((ethylimino)methylene)-N3,N3-dimethylpropane-1,3-diamine hydrochloride (2.36 g, 15.22 mmol) in CH 2 Cl 2 (20 mL) was added 3-chloro-N-ethyl-1-(pyridin-3-yl)-1H-pyrazol-4-amine, 2HCl (3.0 g, 10 mmol).
- N,N-dimethylpyridin-4-amine (0.82 g, 6.73 mmol) and N1-((ethylimino)methylene)-N3,N3-dimethylpropane-1,3-diamine, HCl (1.76 g, 9.18 mmol), and the mixture was stirred at room temperature for 16 h. The mixture was diluted with CH 2 Cl 2 (100 mL) and water (50 mL) and the organic phase separated.
- N-(3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl)-N-ethyl-3-mercatopropanamide 100 mg, 0.322 mmol
- sodium hydride 60% dispersion in oil, 13.5 mg, 0.34 mmol
- the resulting mixture was stirred at room temperature for 10 min followed by addition of 2-(bromomethyl)-1,1-difluorocyclopropane (60 mg, 0.35 mmol).
- the mixture was stirred at room temperature for 24 h and diluted with saturated aqueous ammonium chloride and ethyl acetate.
- Molecules 624, 625, 629, 633, 643 653 in Table 1 were made in accordance with the procedures disclosed in Example 89.
- Molecules 622, 630, 645 in Table 1 were made in accordance with the procedures disclosed in Example 90.
- the mixture was diluted with saturated aqueous ammonium chloride (5 mL) and ethyl acetate (15 mL), and the organic phase was separated. The aqueous phase was extracted with ethyl acetate (5 mL) and the combined organic phase was washed with brine, dried over MgSO 4 and concentrated in vacuo to give an oily residue.
- Molecule 651 in Table 1 was made in accordance with the procedures disclosed in Example 96.
- the mixture was diluted with saturated aqueous NH 4 Cl and ethyl acetate and the organic phase separated.
- the aqueous phase was extracted with ethyl acetate and the combined organic phase was washed with brine, dried over MgSO 4 and concentrated in vacuo to give a light brown oil.
- the mixture was diluted with saturated aqueous ammonium chloride (5 mL) and ethyl acetate (15 mL), and the organic phase was separated. The aqueous phase was extracted with ethyl acetate (5 mL) and the combined organic phase was washed with brine, dried over MgSO 4 and concentrated in vacuo to give an oily residue.
- Molecules 637, 639-642, and 652 in Table 1 were made in accordance with the procedures disclosed in Example 102.
- reaction was warmed to room temperature and stirred for 30 min. The reaction was again cooled at 0° C. and 2-bromo-1,1-difluoroethane (0.101 mL, 1.275 mmol) in THF (2.1 mL) was added. Reaction was warmed to room temperature and stirred overnight. LC-MS analysis indicated presence of two products, the major corresponding to the desired elimination product and the minor corresponding to the initial alkylation. Therefore, the reaction was cooled to 0° C. and transferred to a vial containing additional NaOMe (freshly prepared by mixing NaH (5.86 mg, 0.147 mmol) and MeOH (5.93 ⁇ L, 0.147 mmol) in THF (0.73 mL) at 0° C.
- additional NaOMe freshly prepared by mixing NaH (5.86 mg, 0.147 mmol) and MeOH (5.93 ⁇ L, 0.147 mmol
- reaction was diluted in EtOAc (5 mL) and quenched with H 2 O (5 mL). Aqueous layer was extracted with EtOAc (3 ⁇ 10 mL) and the combined organic extracts were dried over Na 2 SO 4 , filtered, and concentrated in vacuo to give a yellow oil.
- reaction mixture was concentrated and the crude acid chloride was dissolved in DCM (0.3 mL) which was subsequently added to a pre-stirred solution of 3-chloro-N-methyl-1-(pyridin-3-yl)-1H-pyrazol-4-amine dihydrochloride (0.100 g, 0.355 mmol) and N,N-dimethylpyridin-4-amine (0.130 g, 1.065 mmol) in DCM (1.0 mL) and stirred overnight at room temperature.
- the reaction mixture was diluted with saturated NaHCO 3 and extracted with DCM. The organic layer was dried over Na 2 SO 4 , filtered and concentrated.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/788,736 US20130291227A1 (en) | 2012-04-27 | 2013-03-07 | Pesticidal compositions and processes related thereto |
US14/816,295 US9591857B2 (en) | 2012-04-27 | 2015-08-03 | Pesticidal compositions and processes related thereto |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261639274P | 2012-04-27 | 2012-04-27 | |
US13/788,736 US20130291227A1 (en) | 2012-04-27 | 2013-03-07 | Pesticidal compositions and processes related thereto |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/816,295 Continuation US9591857B2 (en) | 2012-04-27 | 2015-08-03 | Pesticidal compositions and processes related thereto |
Publications (1)
Publication Number | Publication Date |
---|---|
US20130291227A1 true US20130291227A1 (en) | 2013-10-31 |
Family
ID=49477805
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/788,736 Abandoned US20130291227A1 (en) | 2012-04-27 | 2013-03-07 | Pesticidal compositions and processes related thereto |
US13/788,850 Expired - Fee Related US8901153B2 (en) | 2012-04-27 | 2013-03-07 | Pesticidal compositions and processes related thereto |
US14/816,295 Expired - Fee Related US9591857B2 (en) | 2012-04-27 | 2015-08-03 | Pesticidal compositions and processes related thereto |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/788,850 Expired - Fee Related US8901153B2 (en) | 2012-04-27 | 2013-03-07 | Pesticidal compositions and processes related thereto |
US14/816,295 Expired - Fee Related US9591857B2 (en) | 2012-04-27 | 2015-08-03 | Pesticidal compositions and processes related thereto |
Country Status (23)
Country | Link |
---|---|
US (3) | US20130291227A1 (es) |
EP (2) | EP2852284A4 (es) |
JP (4) | JP6463670B2 (es) |
KR (2) | KR20150017709A (es) |
CN (4) | CN105732579A (es) |
AP (2) | AP2014008072A0 (es) |
AR (2) | AR090868A1 (es) |
AU (4) | AU2013252946A1 (es) |
BR (3) | BR112014026746A2 (es) |
CA (2) | CA2870090A1 (es) |
CL (2) | CL2014002900A1 (es) |
CO (2) | CO7111287A2 (es) |
HK (2) | HK1202225A1 (es) |
IL (3) | IL235322A0 (es) |
MA (2) | MA37571A1 (es) |
MX (2) | MX2014013069A (es) |
NZ (3) | NZ715920A (es) |
PH (2) | PH12014502398B1 (es) |
RU (3) | RU2627654C2 (es) |
TW (4) | TWI594994B (es) |
UA (1) | UA115144C2 (es) |
WO (2) | WO2013162716A2 (es) |
ZA (2) | ZA201408647B (es) |
Cited By (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130288893A1 (en) * | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US20140213448A1 (en) * | 2012-04-27 | 2014-07-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US8815271B2 (en) | 2010-11-03 | 2014-08-26 | Dow Agrosciences, Llc. | Pesticidal compositions and processes related thereto |
US20150112073A1 (en) * | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US20150111743A1 (en) * | 2013-10-22 | 2015-04-23 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US20150111732A1 (en) * | 2013-10-22 | 2015-04-23 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9024031B1 (en) | 2014-08-19 | 2015-05-05 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9029555B1 (en) | 2014-07-31 | 2015-05-12 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9029556B1 (en) | 2014-07-31 | 2015-05-12 | Dow Argosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9044017B2 (en) | 2013-10-17 | 2015-06-02 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
WO2015106050A1 (en) * | 2014-01-10 | 2015-07-16 | Valent Biosciences Corporation | (s)-3'-methyl-abscisic acid and esters thereof |
US9085552B1 (en) | 2014-09-12 | 2015-07-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9085564B2 (en) | 2013-10-17 | 2015-07-21 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9102654B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9102655B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9108946B2 (en) | 2013-10-17 | 2015-08-18 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9137998B2 (en) | 2013-10-22 | 2015-09-22 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9144241B2 (en) | 2013-10-22 | 2015-09-29 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9149040B2 (en) | 2013-10-22 | 2015-10-06 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9155304B2 (en) | 2013-10-22 | 2015-10-13 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9174962B2 (en) | 2013-10-17 | 2015-11-03 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9199964B1 (en) | 2014-07-31 | 2015-12-01 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9282740B2 (en) | 2013-10-22 | 2016-03-15 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9295260B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9295258B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9445597B2 (en) | 2013-10-22 | 2016-09-20 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9474276B2 (en) | 2013-10-22 | 2016-10-25 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9491944B2 (en) | 2013-10-22 | 2016-11-15 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9549560B2 (en) | 2013-10-22 | 2017-01-24 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
WO2017034570A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034577A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034573A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034571A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034569A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034579A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034572A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
US9655365B2 (en) | 2011-10-26 | 2017-05-23 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
WO2017086971A1 (en) * | 2015-11-19 | 2017-05-26 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017086972A1 (en) * | 2015-11-19 | 2017-05-26 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9788545B2 (en) | 2013-10-22 | 2017-10-17 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9788546B2 (en) | 2013-10-22 | 2017-10-17 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9801376B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9801383B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
WO2018039028A1 (en) * | 2016-08-26 | 2018-03-01 | Dow Agrosciences Llc | Foliar applications for controlling lepidopteran pests for fruits and/or fruit trees |
WO2018125820A1 (en) * | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US10100033B2 (en) | 2016-12-29 | 2018-10-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US20190045784A1 (en) * | 2016-02-26 | 2019-02-14 | Basf Se | Fungicidal mixtures comprising fluxapyroxad |
US10233155B2 (en) | 2016-12-29 | 2019-03-19 | Dow Agrosciences Llc | Processes for the preparation of pesticide compounds |
US10894783B2 (en) | 2018-06-08 | 2021-01-19 | Dow Agrosciences Llc | Molecule having pesticidal utility, and compositions, and processes, related thereto |
Families Citing this family (278)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015061141A1 (en) * | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9078443B1 (en) | 2014-01-31 | 2015-07-14 | Fmc Corporation | Methods for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides |
AR102315A1 (es) * | 2014-04-02 | 2017-02-22 | Bayer Cropscience Ag | Derivados de pirazolil-nicotin(tio)amida sustituidos y su uso como fungicidas |
UA120628C2 (uk) | 2014-11-07 | 2020-01-10 | Басф Се | Пестицидні суміші |
GB201502164D0 (en) * | 2015-02-10 | 2015-03-25 | Syngenta Participations Ag | Herbicidal compounds |
CN104663655B (zh) * | 2015-03-19 | 2016-08-24 | 京博农化科技股份有限公司 | 一种稻瘟酰胺或稻瘟酰胺组合物的用途及其使用方法 |
US20180077934A1 (en) * | 2015-04-22 | 2018-03-22 | Basf Se | Molluscicide and bait composition comprising a molluscicide |
AR104658A1 (es) * | 2015-05-18 | 2017-08-02 | Sinochem Corp | Compuestos de pirazol sustituido que contienen pirimidinilo, la preparación y aplicación de los mismos |
CN104996457B (zh) * | 2015-07-31 | 2017-04-19 | 广西田园生化股份有限公司 | 一种含毒氟磷和氰烯菌酯的杀菌组合物及杀菌剂 |
BR102016019512B8 (pt) * | 2015-08-26 | 2022-10-11 | Dow Agrosciences Llc | Composição compreendendo complexo protetor compreendendo cloquintocet e polímeros ou oligômeros contendo amina, seu método de preparação, e método para controle da vegetação indesejável |
PE20181198A1 (es) | 2015-10-26 | 2018-07-23 | Bayer Cropscience Ag | Derivados de heterociclos biciclicos condensados como agentes de control de plagas |
WO2017093180A1 (de) | 2015-12-01 | 2017-06-08 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
RU2018123928A (ru) | 2015-12-03 | 2020-01-13 | Байер Кропсайенс Акциенгезельшафт | Мезоионные галогенированные 3-(ацетил)-1-[(1,3-тиазол-5-ил)метил]-1н-имидазо[1,2-а]пиридин-4-иум-2-олатные производные и родственные соединения в качестве инсектицидов |
CN105503688B (zh) * | 2016-01-07 | 2018-03-13 | 武汉大学 | 一种烯烃的卤化三氟甲基化反应的方法 |
CN108697091B (zh) | 2016-01-25 | 2021-07-23 | 美国陶氏益农公司 | 具有杀虫效用的分子,以及与其相关的中间体、组合物和方法 |
EP3202267A1 (en) | 2016-02-05 | 2017-08-09 | Basf Se | Pesticidal mixtures |
CN109071506B (zh) | 2016-02-11 | 2021-03-02 | 拜耳作物科学股份公司 | 作为有害生物防治剂的取代的2-(杂)芳基咪唑基羧酰胺 |
KR20180107142A (ko) | 2016-02-11 | 2018-10-01 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 해충 방제제로서의 치환된 2-옥시이미다졸릴-카르복스아미드 |
BR112018015520B8 (pt) | 2016-02-19 | 2022-09-06 | Basf Se | Misturas de pesticidas, métodos de controle de insetos, de proteção de plantas e de proteção de material de propagação vegetal, semente revestida e composição pesticida |
WO2017144341A1 (de) | 2016-02-23 | 2017-08-31 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
EP3210468A1 (de) | 2016-02-26 | 2017-08-30 | Bayer CropScience Aktiengesellschaft | Lösungsmittelfreie formulierungen von niedrig schmelzenden wirkstoffen |
EP3429355B1 (de) | 2016-03-15 | 2020-02-05 | Bayer CropScience AG | Substituierte sulfonylamide zur bekämpfung tierischer schädlinge |
CA3015744A1 (en) | 2016-03-16 | 2017-09-21 | Basf Se | Use of 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one for combating resistant phytopathogenic fungi on cereals |
EP3429997A1 (de) | 2016-03-16 | 2019-01-23 | Bayer CropScience Aktiengesellschaft | N-(cyanbenzyl)-6-(cyclopropylcarbonylamino)-4-(phenyl)-pyridin-2-carboxamid-derivate und verwandte verbindungen als pestizide pflanzenschutzmittel |
BR112018068705B1 (pt) | 2016-03-16 | 2022-09-06 | Basf Se | Método para controlar fungos fitopatogênicos |
BR112018068695B1 (pt) | 2016-03-16 | 2022-12-27 | Basf Se | Uso de um composto e método para controlar fungos fitopatogênicos |
WO2017174414A1 (de) | 2016-04-05 | 2017-10-12 | Bayer Cropscience Aktiengesellschaft | Naphthalin-derivate als schädlingsbekämpfungsmittel |
MX2018012544A (es) | 2016-04-15 | 2019-01-31 | Bayer Animal Health Gmbh | Nuevos derivados de pirazolopirimidina. |
AU2017256505B2 (en) | 2016-04-25 | 2021-02-18 | Bayer Cropscience Aktiengesellschaft | Substituted 2-alkylimidazolyl-carboxamides as pest control agents |
EP3241830A1 (de) | 2016-05-04 | 2017-11-08 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
EP3245865A1 (en) | 2016-05-17 | 2017-11-22 | Bayer CropScience Aktiengesellschaft | Method for increasing yield in brassicaceae |
WO2017198450A1 (en) | 2016-05-15 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in maize |
WO2017198449A1 (en) | 2016-05-15 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in brassicaceae |
WO2017198453A1 (en) | 2016-05-16 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in potato, tomato or alfalfa |
WO2017198452A1 (en) | 2016-05-16 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in soybean |
WO2017198451A1 (en) | 2016-05-17 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in small grain cereals such as wheat and rice |
WO2017198454A1 (en) | 2016-05-17 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in cotton |
WO2017198455A2 (en) | 2016-05-17 | 2017-11-23 | Bayer Cropscience Nv | Method for increasing yield in beta spp. plants |
CA3031139A1 (en) | 2016-07-19 | 2018-01-25 | Bayer Cropscience Aktiengesellschaft | Condensed bicyclic heterocycle derivatives as pest control agents |
WO2018015843A1 (en) * | 2016-07-21 | 2018-01-25 | Basf Se | Pesticidally active mixtures comprising afidoypropen |
EA039895B1 (ru) | 2016-07-29 | 2022-03-24 | Байер Кропсайенс Акциенгезельшафт | Способ обработки семян до посева, препарат для обработки семян, состоящий из спор p.bilaii и порошка талька, семена, обработанные указанным препаратом, способ получения указанного препарата и его применение для обработки семян |
PE20190629A1 (es) | 2016-08-10 | 2019-04-26 | Bayer Cropscience Ag | 2-heterociclilimidazolilcarboxamidas sustituidas como pesticidas |
PE20190800A1 (es) | 2016-08-15 | 2019-06-10 | Bayer Cropscience Ag | Derivados del heterociclo biciclico condensado como agentes de control de plagas |
US10611779B2 (en) | 2016-09-19 | 2020-04-07 | Bayer Cropscience Aktiengesellschaft | Fused bicyclic heterocycle derivatives as pesticides |
KR102477315B1 (ko) | 2016-10-06 | 2022-12-13 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 해충 방제제로서의 2-(헤트)아릴-치환된 융합 비사이클릭 헤테로사이클 유도체 |
WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
TW201822637A (zh) | 2016-11-07 | 2018-07-01 | 德商拜耳廠股份有限公司 | 用於控制動物害蟲的經取代磺醯胺類 |
SI3538512T1 (sl) | 2016-11-11 | 2021-09-30 | Bayer Animal Health Gmbh | Novi antihelmintični kinolin-3-karboksamidni derivati |
EP3544978B1 (de) | 2016-11-23 | 2020-11-04 | Bayer CropScience Aktiengesellschaft | 2-[3-(alkylsulfonyl)-2h-indazol-2-yl]-3h-imidazo[4,5-b]pyridin-derivate und ähnliche verbindungen als schädlingsbekämpfungsmittel |
EP3400801A1 (en) | 2017-05-10 | 2018-11-14 | Bayer CropScience Aktiengesellschaft | Plant health effect of purpureocillium lilacinum |
US20190382358A1 (en) | 2016-12-16 | 2019-12-19 | Bayer Cropscience Aktiengesellschaft | Heterocyclic compounds as pesticides |
JP2020502110A (ja) | 2016-12-16 | 2020-01-23 | バイエル・アクチエンゲゼルシヤフト | 殺虫剤として使用するためのメソイオン性イミダゾピリジン類 |
BR112019008238B1 (pt) | 2016-12-29 | 2022-11-29 | Dow Agrosciences Llc | Processos para preparação de compostos pesticidas |
KR102515694B1 (ko) | 2017-01-10 | 2023-03-29 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로사이클 유도체 |
UY37557A (es) | 2017-01-10 | 2018-07-31 | Bayer Ag | Derivados heterocíclicos como pesticidas |
EP3570836A4 (en) * | 2017-01-23 | 2020-08-19 | The University of Hawaii | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS |
WO2018138050A1 (de) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
CA3050864A1 (en) | 2017-01-26 | 2018-08-02 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients |
TW201833107A (zh) | 2017-02-06 | 2018-09-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之經2-(雜)芳基取代的稠合雜環衍生物 |
EP3369320A1 (de) | 2017-03-02 | 2018-09-05 | Bayer CropScience Aktiengesellschaft | Wirkstoff zur bekämpfung von wanzen |
TWI780112B (zh) | 2017-03-31 | 2022-10-11 | 美商科迪華農業科技有限責任公司 | 具有殺蟲效用之分子,及其相關之中間物、組成物暨方法 |
CA3059702A1 (en) | 2017-04-10 | 2018-10-18 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients |
CA3059675A1 (en) | 2017-04-10 | 2018-10-18 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients |
CN110234627B (zh) | 2017-04-11 | 2023-09-01 | 三井化学植保株式会社 | 吡啶酮化合物及以吡啶酮化合物作为有效成分的农园艺用杀菌剂 |
BR112019021356A2 (pt) | 2017-04-12 | 2020-05-05 | Bayer Ag | imidazopiridinas mesoiônicas para uso como inseticidas |
US10993439B2 (en) | 2017-04-21 | 2021-05-04 | Bayer Aktiengesellschaft | Mesoionic imidazopyridines as insecticides |
EP3615540B1 (de) | 2017-04-24 | 2022-04-27 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
CN110536892B (zh) | 2017-04-27 | 2023-05-12 | 拜耳动物保健有限责任公司 | 新的二环吡唑衍生物 |
TWI782983B (zh) | 2017-04-27 | 2022-11-11 | 德商拜耳廠股份有限公司 | 雜芳基苯基胺基喹啉及類似物 |
WO2018202501A1 (de) | 2017-05-02 | 2018-11-08 | Bayer Aktiengesellschaft | 2-(het)aryl-substituierte kondensierte heterocyclen-derivate als schädlingsbekämpfungsmittel |
JP7119003B2 (ja) | 2017-05-02 | 2022-08-16 | バイエル・アクチエンゲゼルシヤフト | 有害生物防除剤としての2-(ヘタ)アリール置換縮合二環式ヘテロ環式誘導体 |
JP2020518589A (ja) | 2017-05-03 | 2020-06-25 | バイエル・アクチエンゲゼルシヤフト | トリ置換シリルベンジルベンゾイミダゾール類及び類縁体 |
WO2018202706A1 (en) | 2017-05-03 | 2018-11-08 | Bayer Aktiengesellschaft | Trisubstitutedsilylheteroaryloxyquinolines and analogues |
EP3619197A1 (en) | 2017-05-03 | 2020-03-11 | Bayer Aktiengesellschaft | Trisubstitutedsilylmethylphenoxyquinolines and analogues |
SI3619196T1 (sl) | 2017-05-04 | 2022-10-28 | Bayer Cropscience Aktiengesellschaft | 2-((2-(feniloksimetil)piridin-5-il)oksi)-etanaminski derivati in sorodne spojine kot sredstva za zatiranje škodljivcev, npr. za zaščito rastlin |
WO2018202525A1 (en) | 2017-05-04 | 2018-11-08 | Bayer Cropscience Aktiengesellschaft | Phenoxyethanamine derivatives for controlling pests |
WO2018225829A1 (ja) | 2017-06-08 | 2018-12-13 | 三井化学アグロ株式会社 | ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤 |
EP3615527B1 (en) | 2017-06-30 | 2024-03-06 | Elanco Animal Health GmbH | New azaquinoline derivatives |
WO2019007887A1 (de) | 2017-07-06 | 2019-01-10 | Bayer Aktiengesellschaft | Insektizide und fungizide wirkstoffkombinationen |
EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
EP3634959A1 (en) | 2017-08-04 | 2020-04-15 | Bayer Animal Health GmbH | Quinoline derivatives for treating infections with helminths |
CN109384728A (zh) * | 2017-08-07 | 2019-02-26 | 华东理工大学 | 嘧菌酯通道型溶剂化物及其制备方法 |
BR112020003109A2 (pt) | 2017-08-17 | 2020-08-04 | Bayer Cropscience Lp | composições dispersíveis em fertilizantes líquidos e métodos para as mesmas |
KR102600330B1 (ko) | 2017-08-22 | 2023-11-10 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로시클렌 유도체 |
CN107432281A (zh) * | 2017-08-28 | 2017-12-05 | 长沙理工大学 | 一种香石竹矮控剂及其使用方法 |
AU2018335796A1 (en) | 2017-09-20 | 2020-05-07 | Mitsui Chemicals Agro, Inc. | Prolonged ectoparasite-controlling agent for animal |
EP3691990A4 (en) * | 2017-09-27 | 2021-06-30 | Arkema Inc. | HALOGENATED HETEROALKENYL AND HETEROALKYL FUNCTIONALIZED ORGANIC COMPOUNDS AND METHOD FOR THEIR PRODUCTION |
CN117430622A (zh) | 2017-10-04 | 2024-01-23 | 拜耳公司 | 用作害虫防治剂的杂环化合物的衍生物 |
EP3473103A1 (de) | 2017-10-17 | 2019-04-24 | Bayer AG | Wässrige suspensionskonzentrate auf basis von 2-[(2,4-dichlorphenyl)-methyl]-4,4'-dimethyl-3-isoxazolidinon |
MX2020003958A (es) | 2017-10-18 | 2020-08-03 | Bayer Ag | Combinaciones de compuestos activos con propiedades insecticidas/acaricidas. |
PT3697217T (pt) | 2017-10-18 | 2021-10-14 | Bayer Ag | Combinações de composto ativo que têm propriedades inseticidas/acaricidas |
AR113444A1 (es) | 2017-10-18 | 2020-05-06 | Bayer Ag | Combinaciones de compuestos activos con propiedades insecticidas / acaricidas |
WO2019076749A1 (en) | 2017-10-18 | 2019-04-25 | Bayer Aktiengesellschaft | COMBINATIONS OF ACTIVE COMPOUNDS HAVING INSECTICIDAL / ACARICIDE PROPERTIES |
CN111246742B (zh) | 2017-10-18 | 2022-09-23 | 拜耳公司 | 具有杀虫/杀螨特性的活性化合物结合物 |
EP3473100A1 (en) | 2017-10-18 | 2019-04-24 | Bayer Aktiengesellschaft | Active compound combinations having insecticidal/acaricidal properties |
JP2021502402A (ja) | 2017-11-13 | 2021-01-28 | バイエル アクチェンゲゼルシャフトBayer Aktiengesellschaft | テトラゾリルプロピル誘導体および殺真菌剤としてのそれらの使用 |
CN111601802A (zh) | 2017-11-28 | 2020-08-28 | 拜耳股份有限公司 | 作为杀虫剂的杂环化合物 |
WO2019105871A1 (de) | 2017-11-29 | 2019-06-06 | Bayer Aktiengesellschaft | Stickstoffhaltige heterocyclen als schädlingsbekämpfungsmittel |
TW201927768A (zh) | 2017-12-21 | 2019-07-16 | 德商拜耳廠股份有限公司 | 三取代矽基甲基雜芳氧基喹啉及類似物 |
EP3305786A3 (de) | 2018-01-22 | 2018-07-25 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
US20210009541A1 (en) | 2018-02-12 | 2021-01-14 | Bayer Aktiengesellschaft | Fungicidal oxadiazoles |
WO2019162228A1 (en) | 2018-02-21 | 2019-08-29 | Bayer Aktiengesellschaft | 1-(5-substituted imidazol-1-yl)but-3-en derivatives and their use as fungicides |
KR20200122353A (ko) | 2018-02-21 | 2020-10-27 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 축합 바이시클릭 헤테로시클릭 유도체 |
KR20200129128A (ko) | 2018-03-08 | 2020-11-17 | 바이엘 악티엔게젤샤프트 | 식물 보호에서 살충제로서의 헤테로아릴-트리아졸 및 헤테로아릴-테트라졸 화합물의 용도 |
KR20200131269A (ko) | 2018-03-12 | 2020-11-23 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 융합된 비시클릭 헤테로시클릭 유도체 |
WO2019197371A1 (en) | 2018-04-10 | 2019-10-17 | Bayer Aktiengesellschaft | Oxadiazoline derivatives |
EP3904349B1 (en) | 2018-04-12 | 2023-08-23 | Bayer Aktiengesellschaft | N-(cyclopropylmethyl)-5-(methylsulfonyl)-n-{1-[1-(pyrimidin-2-yl)-1h-1,2,4-triazol-5-yl]ethyl}heterocyclyl amide derivatives and similar compounds as pesticides |
WO2019197623A1 (de) | 2018-04-13 | 2019-10-17 | Bayer Aktiengesellschaft | Wirkstoffkombinationen mit insektiziden, nematiziden und akariziden eigenschaften |
WO2019197615A1 (de) | 2018-04-13 | 2019-10-17 | Bayer Aktiengesellschaft | Wirkstoffkombinationen mit fungiziden, insektiziden und akariziden eigenschaften |
UY38184A (es) | 2018-04-17 | 2019-10-31 | Bayer Ag | Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas |
AU2019254616A1 (en) | 2018-04-20 | 2020-10-08 | Bayer Aktiengesellschaft | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides |
MX2020011061A (es) | 2018-04-20 | 2020-11-06 | Bayer Ag | Derivados de heterocicleno como agentes para el control de plagas. |
UA127065C2 (uk) | 2018-04-25 | 2023-03-29 | Баєр Акціенгезельшафт | Нові гетероарил-триазольні та гетероарил-тетразольні сполуки як пестициди |
MX2020011873A (es) | 2018-05-09 | 2021-01-20 | Bayer Animal Health Gmbh | Nuevos derivados de quinolina. |
WO2019224143A1 (de) | 2018-05-24 | 2019-11-28 | Bayer Aktiengesellschaft | Wirkstoffkombinationen mit insektiziden, nematiziden und akariziden eigenschaften |
US20210267194A1 (en) | 2018-06-25 | 2021-09-02 | Bayer Cropscience Lp | Seed treatment method |
MX2020013767A (es) | 2018-06-26 | 2021-03-02 | Bayer Ag | Derivados heterociclicos como plaguicidas. |
WO2020002189A1 (de) | 2018-06-27 | 2020-01-02 | Bayer Aktiengesellschaft | Wirkstoffkombinationen |
EP3586630A1 (en) | 2018-06-28 | 2020-01-01 | Bayer AG | Active compound combinations having insecticidal/acaricidal properties |
PL3818051T3 (pl) | 2018-07-05 | 2022-11-28 | Bayer Aktiengesellschaft | Podstawione tiofenokarboksyamidy i analogi jako środki przeciwbakteryjne |
JP7291143B2 (ja) | 2018-07-25 | 2023-06-14 | 三井化学クロップ&ライフソリューション株式会社 | ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤 |
WO2020020813A1 (en) | 2018-07-25 | 2020-01-30 | Bayer Aktiengesellschaft | Fungicidal active compound combinations |
WO2020020816A1 (en) | 2018-07-26 | 2020-01-30 | Bayer Aktiengesellschaft | Novel triazole derivatives |
US20210321610A1 (en) | 2018-07-27 | 2021-10-21 | Bayer Aktiengesellschaft | Controlled release formulations for agrochemicals |
BR112021001633A2 (pt) | 2018-07-31 | 2021-05-04 | Bayer Aktiengesellschaft | formulações de liberação controlada com lignina para agroquímicos |
WO2020043650A1 (en) | 2018-08-29 | 2020-03-05 | Bayer Aktiengesellschaft | Active compound combinations having insecticidal/acaricidal properties |
AR116314A1 (es) | 2018-09-13 | 2021-04-21 | Bayer Ag | Derivados heterocíclicos como plaguicidas |
JP2022500459A (ja) | 2018-09-17 | 2022-01-04 | バイエル・アクチエンゲゼルシヤフト | 穀物中の麦角病菌の制御と菌核の低減のための殺菌剤イソフクシプラムの使用 |
WO2020070050A1 (en) | 2018-10-01 | 2020-04-09 | Bayer Aktiengesellschaft | Fungicidal 5-substituted imidazol-1-yl carbinol derivatives |
EP3636644A1 (de) | 2018-10-11 | 2020-04-15 | Bayer Aktiengesellschaft | Mesoionische imidazopyridine als insektizide |
WO2020078839A1 (de) | 2018-10-16 | 2020-04-23 | Bayer Aktiengesellschaft | Wirkstoffkombinationen |
AR116747A1 (es) | 2018-10-18 | 2021-06-09 | Bayer Ag | Piridilfenilaminoquinolinas y análogos de las mismas |
AR116746A1 (es) | 2018-10-18 | 2021-06-09 | Bayer Ag | Heteroarilaminoquinolinas y análogos de las mismas |
TW202028193A (zh) | 2018-10-20 | 2020-08-01 | 德商拜耳廠股份有限公司 | 氧雜環丁基苯氧基喹啉及類似物 |
EP3643711A1 (en) | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
CN109769807B9 (zh) * | 2018-11-14 | 2021-02-09 | 浙江农林大学 | 一种具有双分子结构的缓释灭藻微胶囊及其制备方法 |
AR117169A1 (es) | 2018-11-28 | 2021-07-14 | Bayer Ag | (tio)amidas de piridazina como compuestos fungicidas |
EP3890489B1 (de) | 2018-12-07 | 2023-01-04 | Bayer Aktiengesellschaft | Herbizide zusammensetzungen |
EP3890488B1 (de) | 2018-12-07 | 2023-01-04 | Bayer Aktiengesellschaft | Herbizide zusammensetzungen |
EP3620052A1 (en) | 2018-12-12 | 2020-03-11 | Bayer Aktiengesellschaft | Use of phenoxypyridinyl-substituted (1h-1,2,4-triazol-1-yl)alcohols for controlling fungicidal diseases in maize |
CN109369617B (zh) * | 2018-12-13 | 2020-07-31 | 中国科学院福建物质结构研究所 | 一种1-(2-吡啶基)-吡唑-3-甲酸及其衍生物的合成方法 |
US20220061323A1 (en) | 2018-12-18 | 2022-03-03 | Bayer Aktiengesellschaft | Active compound combinations having insecticidal/acaricidal properties |
AR117461A1 (es) | 2018-12-20 | 2021-08-04 | Bayer Ag | Compuestos de heterociclil piridazina como fungicidas |
EP3669652A1 (en) | 2018-12-21 | 2020-06-24 | Bayer AG | Active compound combination |
CN113473860A (zh) | 2018-12-21 | 2021-10-01 | 拜耳公司 | 作为新的抗真菌剂的1,3,4-噁二唑及其衍生物 |
EP3679789A1 (en) | 2019-01-08 | 2020-07-15 | Bayer AG | Active compound combinations |
EP3679791A1 (en) | 2019-01-08 | 2020-07-15 | Bayer AG | Active compound combinations |
EP3679793A1 (en) | 2019-01-08 | 2020-07-15 | Bayer AG | Active compound combinations |
EP3679792A1 (en) | 2019-01-08 | 2020-07-15 | Bayer AG | Active compound combinations |
EP3679790A1 (en) | 2019-01-08 | 2020-07-15 | Bayer AG | Active compound combinations |
EP3545764A1 (en) | 2019-02-12 | 2019-10-02 | Bayer AG | Crystal form of 2-({2-fluoro-4-methyl-5-[(r)-(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2- trifluoroethyl)-1,3-thiazolidin-4-one |
BR112021010400A2 (pt) | 2019-02-26 | 2021-08-24 | Bayer Aktiengesellschaft | Derivados heterocíclicos bicíclicos condensados como agentes de controle de praga |
BR112021010430A2 (pt) | 2019-02-26 | 2021-08-24 | Bayer Aktiengesellschaft | Derivados de heterociclo bicíclico fundido como pesticidas |
US20220132851A1 (en) | 2019-03-01 | 2022-05-05 | Bayer Aktiengesellschaft | Active compound combinations having insecticidal/acaricidal properties |
WO2020178307A1 (en) | 2019-03-05 | 2020-09-10 | Bayer Aktiengesellschaft | Active compound combination |
WO2020182929A1 (en) | 2019-03-13 | 2020-09-17 | Bayer Aktiengesellschaft | Substituted ureas and derivatives as new antifungal agents |
WO2020187656A1 (en) | 2019-03-15 | 2020-09-24 | Bayer Aktiengesellschaft | Active compound combinations having insecticidal/acaricidal properties |
EP3564225A1 (en) | 2019-03-21 | 2019-11-06 | Bayer Aktiengesellschaft | Crystalline form of spiromesifen |
EP3725788A1 (en) | 2019-04-15 | 2020-10-21 | Bayer AG | Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides |
BR112021022124A2 (pt) | 2019-05-08 | 2022-01-04 | Bayer Ag | Combinação de compostos ativos |
CN114025609A (zh) | 2019-05-08 | 2022-02-08 | 拜耳公司 | 用于除草剂的高铺展ulv制剂 |
EP3965575A1 (en) | 2019-05-10 | 2022-03-16 | Bayer CropScience LP | Active compound combinations |
WO2020229398A1 (de) | 2019-05-14 | 2020-11-19 | Bayer Aktiengesellschaft | (1-alkenyl)-substituierte pyrazole und triazole als schädlingsbekämpfungsmittel |
EP3750888A1 (en) | 2019-06-12 | 2020-12-16 | Bayer Aktiengesellschaft | Crystalline form a of 1,4-dimethyl-2-[2-(pyridin-3-yl)-2h-indazol-5-yl]-1,2,4-triazolidine-3,5-dione |
WO2020254493A1 (en) | 2019-06-21 | 2020-12-24 | Bayer Aktiengesellschaft | Thienylhydroxyisoxazolines and derivatives thereof |
EP3986891A1 (en) | 2019-06-21 | 2022-04-27 | Bayer Aktiengesellschaft | Hydroxyisoxazolines and derivatives thereof |
EP3986892A1 (en) | 2019-06-21 | 2022-04-27 | Bayer Aktiengesellschaft | Hydroxyisoxazolines and use thereof as fungicides |
EP3986877A1 (en) | 2019-06-21 | 2022-04-27 | Bayer Aktiengesellschaft | Hydroxyisoxazolines and derivatives thereof |
WO2020254494A1 (en) | 2019-06-21 | 2020-12-24 | Bayer Aktiengesellschaft | Fungicidal oxadiazoles |
EP3986874A1 (en) | 2019-06-21 | 2022-04-27 | Bayer Aktiengesellschaft | Benzylphenyl hydroxyisoxazolines and analogues as new antifungal agents |
BR112021025865A2 (pt) | 2019-06-21 | 2022-03-03 | Bayer Ag | Hidróxi-isoxazolinas e derivados das mesmas |
EP3986875A1 (en) | 2019-06-21 | 2022-04-27 | Bayer Aktiengesellschaft | Phenoxyphenyl hydroxyisoxazolines and analogues as new antifungal agents |
US20220312773A1 (en) | 2019-06-24 | 2022-10-06 | Auburn University | A bacillus strain and methods of its use for plant growth promotion |
EP3608311A1 (en) | 2019-06-28 | 2020-02-12 | Bayer AG | Crystalline form a of n-[4-chloro-3-[(1-cyanocyclopropyl)carbamoyl]phenyl]-2-methyl-4-methylsulfonyl-5-(1,1,2,2,2-pentafluoroethyl)pyrazole-3-carboxamide |
MA56441A (fr) | 2019-07-03 | 2022-05-11 | Bayer Ag | Thiophène carboxamides substitués et leurs dérivés comme microbicides |
CA3145581A1 (en) | 2019-07-04 | 2021-01-07 | Bayer Aktiengesellschaft | Herbicidal compositions |
CA3147858A1 (en) | 2019-07-22 | 2021-01-28 | Bayer Aktiengesellschaft | 5-amino substituted pyrazoles and triazoles as pest control agents |
US20220289720A1 (en) * | 2019-07-22 | 2022-09-15 | University Of Hawaii | Aryl sulfonamides as small molecule stat3 inhibitors |
CN114502545A (zh) | 2019-07-23 | 2022-05-13 | 拜耳公司 | 作为农药的新的杂芳基-三唑化合物 |
CA3148209A1 (en) | 2019-07-23 | 2021-01-28 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
EP3771714A1 (de) | 2019-07-30 | 2021-02-03 | Bayer AG | Stickstoffhaltige heterocyclen als schädlingsbekämpfungsmittel |
TW202120490A (zh) | 2019-07-30 | 2021-06-01 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
EP3701796A1 (en) | 2019-08-08 | 2020-09-02 | Bayer AG | Active compound combinations |
CN114615891A (zh) | 2019-09-11 | 2022-06-10 | 拜耳公司 | 基于2-[(2,4-二氯苯基)甲基]-4,4’-二甲基-3-异噁唑烷酮和苗前除草剂的高效制剂 |
WO2021058659A1 (en) | 2019-09-26 | 2021-04-01 | Bayer Aktiengesellschaft | Rnai-mediated pest control |
AU2020363864A1 (en) | 2019-10-09 | 2022-04-21 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
CN114728928A (zh) | 2019-10-09 | 2022-07-08 | 拜耳公司 | 作为农药的新的杂芳基三唑化合物 |
TW202128650A (zh) | 2019-10-11 | 2021-08-01 | 德商拜耳動物保健有限公司 | 作為殺蟲劑之新穎的雜芳基取代之吡𠯤衍生物 |
CN110672753B (zh) * | 2019-11-04 | 2022-05-20 | 青海省农林科学院 | 一种氟咯草酮异构体的拆分和检测方法 |
KR20220098170A (ko) | 2019-11-07 | 2022-07-11 | 바이엘 악티엔게젤샤프트 | 동물 해충 방제를 위한 치환된 술포닐 아미드 |
WO2021097162A1 (en) | 2019-11-13 | 2021-05-20 | Bayer Cropscience Lp | Beneficial combinations with paenibacillus |
TW202134226A (zh) | 2019-11-18 | 2021-09-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
TW202136248A (zh) | 2019-11-25 | 2021-10-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
EP4077317A1 (en) | 2019-12-20 | 2022-10-26 | Bayer Aktiengesellschaft | Thienyloxazolones and analogues |
CN115103840A (zh) | 2019-12-20 | 2022-09-23 | 拜耳公司 | 取代的噻吩甲酰胺、噻吩甲酸及其衍生物 |
EP3845304A1 (en) | 2019-12-30 | 2021-07-07 | Bayer AG | Capsule suspension concentrates based on polyisocyanates and biodegradable amine based cross-linker |
CN115551839A (zh) | 2020-02-18 | 2022-12-30 | 拜耳公司 | 作为农药的杂芳基-三唑化合物 |
EP3868207A1 (de) | 2020-02-24 | 2021-08-25 | Bayer Aktiengesellschaft | Verkapselte pyrethroide mit verbesserter wirksamkeit bei boden- und blattanwendungen |
EP3708565A1 (en) | 2020-03-04 | 2020-09-16 | Bayer AG | Pyrimidinyloxyphenylamidines and the use thereof as fungicides |
BR112022020315A2 (pt) | 2020-04-09 | 2022-12-13 | Bayer Animal Health Gmbh | Novos compostos anti-helmínticos |
AU2021257573A1 (en) | 2020-04-16 | 2022-11-10 | Bayer Aktiengesellschaft | Active compound combinations and fungicide compositions comprising those |
EP4135523A1 (en) | 2020-04-16 | 2023-02-22 | Bayer Aktiengesellschaft | Active compound combinations and fungicide compositions comprising those |
AR121829A1 (es) | 2020-04-16 | 2022-07-13 | Bayer Ag | Combinaciones de compuestos activos y composiciones fungicidas que los comprenden |
AR121830A1 (es) | 2020-04-16 | 2022-07-13 | Bayer Ag | Combinaciones de compuestos activos y composiciones fungicidas que los comprenden |
WO2021209490A1 (en) | 2020-04-16 | 2021-10-21 | Bayer Aktiengesellschaft | Cyclaminephenylaminoquinolines as fungicides |
WO2021209365A1 (en) | 2020-04-16 | 2021-10-21 | Bayer Aktiengesellschaft | Active compound combinations and fungicide compositions comprising those |
MX2022013157A (es) | 2020-04-21 | 2022-11-16 | Bayer Ag | Derivados de heterociclos condensados sustituidos con 2-(het)arilo como plaguicidas. |
TW202208347A (zh) | 2020-05-06 | 2022-03-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物 |
BR112022022595A2 (pt) | 2020-05-06 | 2022-12-20 | Bayer Ag | Piridina (tio)amidas como compostos fungicidas |
JP2023525349A (ja) | 2020-05-12 | 2023-06-15 | バイエル、アクチエンゲゼルシャフト | 殺真菌性化合物としてのトリアジンおよびピリミジン(チオ)アミド化合物 |
US20230192617A1 (en) | 2020-05-19 | 2023-06-22 | Bayer Cropscience Aktiengesellschaft | Azabicyclic(thio)amides as fungicidal compounds |
US20230278994A1 (en) | 2020-06-04 | 2023-09-07 | Bayer Aktiengesellschaft | Heterocyclyl pyrimidines and triazines as novel fungicides |
US20230234945A1 (en) | 2020-06-10 | 2023-07-27 | Bayer Aktiengesellschaft | Azabicyclyl-substituted heterocycles as fungicides |
CA3187296A1 (en) | 2020-06-18 | 2021-12-23 | Bayer Aktiengesellschaft | 3-(pyridazin-4-yl)-5,6-dihydro-4h-1,2,4-oxadiazine derivatives as fungicides for crop protection |
BR112022025710A2 (pt) | 2020-06-19 | 2023-03-07 | Bayer Ag | 1,3,4-oxadiazol pirimidinas e 1,3,4-oxadiazol piridinas como fungicidas |
UY39275A (es) | 2020-06-19 | 2022-01-31 | Bayer Ag | 1,3,4-oxadiazol pirimidinas como fungicidas, procesos e intermediarios para su preparación, métodos de uso y usos de los mismos |
UY39276A (es) | 2020-06-19 | 2022-01-31 | Bayer Ag | Uso de compuestos de 1,3,4–oxadiazol–2–ilpirimidina para controlar microorganismos fitopatógenos, métodos de uso y composiciones. |
WO2021255091A1 (en) | 2020-06-19 | 2021-12-23 | Bayer Aktiengesellschaft | 1,3,4-oxadiazoles and their derivatives as fungicides |
EP3929189A1 (en) | 2020-06-25 | 2021-12-29 | Bayer Animal Health GmbH | Novel heteroaryl-substituted pyrazine derivatives as pesticides |
JP2023531993A (ja) | 2020-06-26 | 2023-07-26 | バイエル・アクチエンゲゼルシヤフト | 生分解性エステル基を含む水性カプセル懸濁製剤 |
KR20230039665A (ko) | 2020-07-02 | 2023-03-21 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로사이클 유도체 |
WO2022033991A1 (de) | 2020-08-13 | 2022-02-17 | Bayer Aktiengesellschaft | 5-amino substituierte triazole als schädlingsbekämpfungsmittel |
WO2022053453A1 (de) | 2020-09-09 | 2022-03-17 | Bayer Aktiengesellschaft | Azolcarboxamide als schädlingsbekämpfungsmittel |
WO2022058327A1 (en) | 2020-09-15 | 2022-03-24 | Bayer Aktiengesellschaft | Substituted ureas and derivatives as new antifungal agents |
EP3974414A1 (de) | 2020-09-25 | 2022-03-30 | Bayer AG | 5-amino substituierte pyrazole und triazole als schädlingsbekämpfungsmittel |
EP3915371A1 (en) | 2020-11-04 | 2021-12-01 | Bayer AG | Active compound combinations and fungicide compositions comprising those |
CN114442601A (zh) * | 2020-11-06 | 2022-05-06 | 郑州宇通客车股份有限公司 | 一种无人驾驶车辆跟踪控制方法及装置 |
EP3994994A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Low drift, rainfastness, high spreading, high uptake and ulv tank mix adjuvant formulation |
EP3994995A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Low drift, rainfastness, high spreading, high uptake and ulv tank mix adjuvant formulation |
EP3994988A1 (en) | 2020-11-08 | 2022-05-11 | Bayer AG | Agrochemical composition with improved drift, spreading and rainfastness properties |
EP3994986A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Agrochemical composition with improved drift and spreading properties |
EP3994990A1 (en) | 2020-11-08 | 2022-05-11 | Bayer AG | Agrochemical composition with improved drift, spreading and uptake properties |
EP3994993A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Low drift, rainfastness, high spreading and ulv tank mix adjuvant formulation |
EP3994985A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Agrochemical composition with improved drift properties |
EP3994992A1 (en) | 2020-11-08 | 2022-05-11 | Bayer AG | Low drift, rainfastness, high uptake and ulv tank mix adjuvant formulation |
EP3994987A1 (en) | 2020-11-08 | 2022-05-11 | Bayer AG | Agrochemical composition with improved drift and uptake properties |
EP3994989A1 (en) | 2020-11-08 | 2022-05-11 | Bayer AG | Agrochemical composition with improved drift, rainfastness and uptake properties |
EP3994991A1 (en) | 2020-11-08 | 2022-05-11 | Bayer Aktiengesellschaft | Agrochemical composition with improved drift, spreading, uptake and rainfastness properties |
EP3915971A1 (en) | 2020-12-16 | 2021-12-01 | Bayer Aktiengesellschaft | Phenyl-s(o)n-phenylamidines and the use thereof as fungicides |
WO2022129190A1 (en) | 2020-12-18 | 2022-06-23 | Bayer Aktiengesellschaft | (hetero)aryl substituted 1,2,4-oxadiazoles as fungicides |
WO2022129196A1 (en) | 2020-12-18 | 2022-06-23 | Bayer Aktiengesellschaft | Heterobicycle substituted 1,2,4-oxadiazoles as fungicides |
WO2022129188A1 (en) | 2020-12-18 | 2022-06-23 | Bayer Aktiengesellschaft | 1,2,4-oxadiazol-3-yl pyrimidines as fungicides |
WO2022152728A1 (de) | 2021-01-15 | 2022-07-21 | Bayer Aktiengesellschaft | Herbizide zusammensetzungen |
EP4036083A1 (de) | 2021-02-02 | 2022-08-03 | Bayer Aktiengesellschaft | 5-oxy substituierte hetereozyklen, als schädlingsbekämpfungsmittel |
EP4294187A1 (en) | 2021-02-19 | 2023-12-27 | Syngenta Crop Protection AG | Insect and acarina pest control |
WO2022200364A1 (en) | 2021-03-25 | 2022-09-29 | Syngenta Crop Protection Ag | Insect, acarina and nematode pest control |
BR112023019400A2 (pt) | 2021-03-30 | 2023-12-05 | Bayer Ag | 3-(hetero)aril-5-clorodifluorometil-1,2,4-oxadiazol como fungicida |
BR112023019788A2 (pt) | 2021-03-30 | 2023-11-07 | Bayer Ag | 3-(hetero)aril-5-clorodifluorometil-1,2,4-oxadiazol como fungicida |
BR112023022763A2 (pt) | 2021-05-06 | 2024-01-02 | Bayer Ag | Imidazóis anulados substituídos por alquilamida e uso dos mesmos como inseticidas |
CN117320553A (zh) | 2021-05-10 | 2023-12-29 | 拜耳公司 | 基于取代的[(1,5-二苯基-1h-1,2,4-三唑-3-基)氧基]乙酸及其盐类安全剂的除草剂/安全剂结合物 |
CN117651702A (zh) | 2021-05-12 | 2024-03-05 | 拜耳公司 | 作为害虫防治剂的2-(杂)芳基取代的稠合杂环衍生物 |
WO2023017120A1 (en) | 2021-08-13 | 2023-02-16 | Bayer Aktiengesellschaft | Active compound combinations and fungicide compositions comprising those |
AU2022335669A1 (en) | 2021-08-25 | 2024-02-01 | Bayer Aktiengesellschaft | Novel pyrazinyl-triazole compounds as pesticides |
EP4144739A1 (de) | 2021-09-02 | 2023-03-08 | Bayer Aktiengesellschaft | Anellierte pyrazole als schädlingsbekämpfungsmittel |
EP4148052A1 (en) | 2021-09-09 | 2023-03-15 | Bayer Animal Health GmbH | New quinoline derivatives |
WO2023078915A1 (en) | 2021-11-03 | 2023-05-11 | Bayer Aktiengesellschaft | Bis(hetero)aryl thioether (thio)amides as fungicidal compounds |
WO2023092050A1 (en) | 2021-11-20 | 2023-05-25 | Bayer Cropscience Lp | Beneficial combinations with recombinant bacillus cells expressing a serine protease |
WO2023099445A1 (en) | 2021-11-30 | 2023-06-08 | Bayer Aktiengesellschaft | Bis(hetero)aryl thioether oxadiazines as fungicidal compounds |
WO2023110656A1 (en) | 2021-12-15 | 2023-06-22 | Bayer Aktiengesellschaft | Spectroscopic solution for non-destructive quantification of one or more chemical substances in a matrix comprising coating and bulk material in a sample, such as coated seeds, using multivariate data analysis |
WO2023137309A2 (en) | 2022-01-14 | 2023-07-20 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
CN114768545B (zh) * | 2022-03-31 | 2023-11-10 | 青岛吉景新型材料有限公司 | 硝酸纤维素微孔膜及其连续制备方法 |
WO2023205602A1 (en) | 2022-04-18 | 2023-10-26 | Basf Corporation | High-load agricultural formulations and methods of making same |
EP4265110A1 (en) | 2022-04-20 | 2023-10-25 | Bayer AG | Water dispersible granules with low melting active ingredients prepared by extrusion |
CN114808175A (zh) * | 2022-04-28 | 2022-07-29 | 解智康 | 一种抗菌除虫面料及其制备方法 |
WO2023213670A1 (en) | 2022-05-03 | 2023-11-09 | Bayer Aktiengesellschaft | Crystalline forms of (5s)-3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4h-1,2,4-oxadiazine |
WO2023213626A1 (en) | 2022-05-03 | 2023-11-09 | Bayer Aktiengesellschaft | Use of (5s)-3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4h-1,2,4-oxadiazine for controlling unwanted microorganisms |
WO2023217619A1 (en) | 2022-05-07 | 2023-11-16 | Bayer Aktiengesellschaft | Low drift aqueous liquid formulations for low, medium, and high spray volume application |
EP4295683A1 (en) | 2022-06-21 | 2023-12-27 | Bayer Aktiengesellschaft | Agrochemical formulations comprising crystalline form a of 4-[(6-chloro-3-pyridylmethyl)(2,2-difluoroethyl)amino]furan-2(5h)-one |
WO2023237444A1 (en) | 2022-06-06 | 2023-12-14 | Bayer Aktiengesellschaft | Agrochemical formulations comprising crystalline form a of 4-[(6-chloro-3-pyridylmethyl)(2,2-difluoroethyl)amino]furan-2(5h)-one |
WO2024013016A1 (en) | 2022-07-11 | 2024-01-18 | Bayer Aktiengesellschaft | Herbicidal compositions |
WO2024013015A1 (en) | 2022-07-11 | 2024-01-18 | Bayer Aktiengesellschaft | Herbicidal compositions |
WO2024068473A1 (de) | 2022-09-27 | 2024-04-04 | Bayer Aktiengesellschaft | Herbizid/safener-kombinationen basierend auf safenern aus der klasse der substituierten [(1,5-diphenyl1h-1,2,4-triazol-3-yl)oxy]essigsäuren sowie deren salze |
EP4295688A1 (en) | 2022-09-28 | 2023-12-27 | Bayer Aktiengesellschaft | Active compound combination |
WO2024068517A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
WO2024068520A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
WO2024068519A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
WO2024068518A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-heteroaryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
EP4353082A1 (en) | 2022-10-14 | 2024-04-17 | Bayer Aktiengesellschaft | Herbicidal compositions |
Family Cites Families (143)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH440292A (de) * | 1962-01-23 | 1967-07-31 | Ciba Geigy | Verfahren zur Herstellung neuer Aminopyrazole |
FR1352288A (fr) * | 1963-01-22 | 1964-02-14 | Ciba Geigy | Procédé de préparation de nouveaux aminopyrazoles, entre autres du 2-butyl (secondaire)-3-amino-5-pyridyl-(3)-pyazole, de ses sels et de son dérivé n-acétylé |
CA962269A (en) | 1971-05-05 | 1975-02-04 | Robert E. Grahame (Jr.) | Thiazoles, and their use as insecticides |
SE426011B (sv) * | 1976-01-30 | 1982-12-06 | Sixten Abrahamsson | Anvendning av en helt eller partiellt deutererad acyklisk, enbasisk karboxyylayra for att skydda ett material i form av levande vexter, utsede och tre mot skadliga svampar |
AU509899B2 (en) | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
FR2517176A1 (fr) | 1981-12-01 | 1983-06-03 | Rhone Poulenc Agrochimie | Association insecticide et acaricide a base de pyrethroide |
US4528291A (en) | 1982-06-22 | 1985-07-09 | Schering Corporation | 2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility |
DE3520328A1 (de) | 1985-06-07 | 1986-12-11 | Bayer Ag, 5090 Leverkusen | 5-amino-4-heterocyclyl-1-pyridyl-pyrazole |
JPS62153273A (ja) * | 1985-12-26 | 1987-07-08 | Tokuyama Soda Co Ltd | ピラゾ−ル化合物 |
DE3618717A1 (de) | 1986-06-04 | 1987-12-10 | Bayer Ag | 5- acylamino-pyrazol-derivate |
JPH07106964B2 (ja) | 1987-01-14 | 1995-11-15 | 株式会社トクヤマ | 摘果剤 |
DE3936622A1 (de) | 1989-11-03 | 1991-05-08 | Bayer Ag | Halogenierte sulfonylaminocarbonyltriazolinone |
US5599944A (en) | 1987-03-24 | 1997-02-04 | Bayer Aktiengesellschaft | Intermediates for herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur |
JPH089541B2 (ja) | 1988-03-07 | 1996-01-31 | 三井東圧化学株式会社 | ピラゾール類を主成分とする脳浮腫抑制剤 |
US5541337A (en) | 1989-04-13 | 1996-07-30 | Bayer Aktiengesellschaft | Substituted 5-alkoxy-1,2,4-triazol-3-(thi)ones |
US5300480A (en) | 1989-04-13 | 1994-04-05 | Bayer Aktiengesellschaft | Herbicidal sulphonylaminocarbonyltriazolinones having two substituents bonded via oxygen |
US5241074A (en) | 1988-05-09 | 1993-08-31 | Bayer Aktiengesellschaft | Sulphonylaminocarbonyltriazolinones |
US5534486A (en) | 1991-04-04 | 1996-07-09 | Bayer Aktiengesellschaft | Herbicidal sulphonylaminocarbonyl triazolinones having substituents bonded via oxygen |
US5366987A (en) | 1991-08-22 | 1994-11-22 | Warner-Lambert Company | Isoxazolyl-substituted alkyl amide ACAT inhibitors |
TW336932B (en) | 1992-12-17 | 1998-07-21 | Pfizer | Amino-substituted pyrazoles |
JPH083229A (ja) | 1994-06-20 | 1996-01-09 | Sumitomo Chem Co Ltd | 共重合体水溶液の製造方法 |
EP0858457A1 (de) | 1995-10-20 | 1998-08-19 | Dr. Karl Thomae GmbH | 5-gliedrige heterocyclen, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung |
US5854265A (en) | 1996-04-03 | 1998-12-29 | Merck & Co., Inc. | Biheteroaryl inhibitors of farnesyl-protein transferase |
JP2000507592A (ja) | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | ファルネシル―タンパク質トランスフェラーゼ阻害剤 |
US5854264A (en) | 1996-07-24 | 1998-12-29 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US6350771B1 (en) * | 1996-12-24 | 2002-02-26 | Rhone-Poulenc, Inc. | Pesticidal 1-arylpyrazoles |
TR199902646T2 (xx) | 1997-04-25 | 2000-05-22 | Pfizer Inc. | Seks�el bozuklu�un tedavisi i�in pirazolopirimidinonlar. |
DE19725450A1 (de) | 1997-06-16 | 1998-12-17 | Hoechst Schering Agrevo Gmbh | 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel |
US6271237B1 (en) | 1997-12-22 | 2001-08-07 | Dupont Pharmaceuticals Company | Nitrogen containing heteromatics with ortho-substituted P1s as factor Xa inhabitors |
GB9827882D0 (en) | 1998-12-17 | 1999-02-10 | Smithkline Beecham Plc | Novel compounds |
SK1812002A3 (en) | 1999-08-12 | 2003-02-04 | Pharmacia Italia Spa | 3(5)-Amino-pyrazole derivatives, process for their preparation and their use as antitumor agents |
HUP0203160A3 (en) | 1999-11-05 | 2006-02-28 | Warner Lambert Co | Prevention of plaque rupture by acat inhibitors |
ATE473206T1 (de) | 2000-02-16 | 2010-07-15 | Ishihara Sangyo Kaisha | Phenacylamin-derivate, ihre herstellung und seuchenmittel, die diese derivate enthalten |
GB0011095D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | astrin and cholecystokinin receptor ligands (III) |
US6645990B2 (en) | 2000-08-15 | 2003-11-11 | Amgen Inc. | Thiazolyl urea compounds and methods of uses |
EP1329160A4 (en) | 2000-08-25 | 2004-04-14 | Sankyo Co | 4-ACYLAMINOPYRAZOL DERIVATIVES |
JP2002138082A (ja) * | 2000-08-25 | 2002-05-14 | Sankyo Co Ltd | 4−アシルアミノピラゾール誘導体 |
US20020134012A1 (en) | 2001-03-21 | 2002-09-26 | Monsanto Technology, L.L.C. | Method of controlling the release of agricultural active ingredients from treated plant seeds |
AU2002246397B2 (en) | 2001-04-16 | 2005-03-24 | Tanabe Seiyaku Co., Ltd. | Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence |
ATE315555T1 (de) | 2001-05-11 | 2006-02-15 | Pfizer Prod Inc | Thiazolderivate und ihre verwendung als cdk- inhibitoren |
ES2241964T3 (es) | 2001-07-05 | 2005-11-01 | Pfizer Products Inc. | Heterocicloalquilsulfufonilpirazoles como agentes antiinflamatorios/abnalgesicos. |
FR2827603B1 (fr) | 2001-07-18 | 2003-10-17 | Oreal | Composes derives de diaminopyrazole substitues par un radical heteroaromatique et leur utilisation en teinture d'oxydation des fibres keratiniques |
GB0123589D0 (en) | 2001-10-01 | 2001-11-21 | Syngenta Participations Ag | Organic compounds |
WO2003053937A1 (fr) | 2001-12-20 | 2003-07-03 | Sds Biotech K.K. | Nouveau derive de pyrazole substitue, procede de production de ce derive et composition herbicide le contenant |
US6936629B2 (en) | 2001-12-21 | 2005-08-30 | Virochem Pharma Inc. | Compounds and methods for the treatment or prevention of flavivirus infections |
US6878196B2 (en) | 2002-01-15 | 2005-04-12 | Fuji Photo Film Co., Ltd. | Ink, ink jet recording method and azo compound |
JP2003212864A (ja) | 2002-01-24 | 2003-07-30 | Sankyo Co Ltd | 5−(m−シアノベンジルアミノ)チアゾール誘導体 |
JP2003313103A (ja) * | 2002-02-20 | 2003-11-06 | Sankyo Agro Kk | 4−アシルアミノピラゾール誘導体を有効成分として含有する農薬 |
EP1480642B1 (en) | 2002-02-25 | 2008-11-26 | Eli Lilly And Company | Peroxisome proliferator activated receptor modulators |
JP2004051628A (ja) | 2002-05-28 | 2004-02-19 | Ishihara Sangyo Kaisha Ltd | ピリジン系化合物又はその塩、それらの製造方法及びそれらを含有する除草剤 |
US6737382B1 (en) | 2002-10-23 | 2004-05-18 | Nippon Soda Co. Ltd. | Insecticidal aminothiazole derivatives |
NZ540161A (en) | 2002-10-30 | 2008-03-28 | Vertex Pharma | Compositions useful as inhibitors of rock and other protein kinases |
US7429581B2 (en) | 2002-12-23 | 2008-09-30 | Sanofi-Aventis Deutschland Gmbh | Pyrazole-derivatives as factor Xa inhibitors |
JP4397615B2 (ja) | 2003-03-27 | 2010-01-13 | 富士フイルム株式会社 | インクジェット用インクおよびインクセット |
GB0312654D0 (en) | 2003-06-03 | 2003-07-09 | Glaxo Group Ltd | Therapeutically useful compounds |
US7514464B2 (en) | 2003-12-18 | 2009-04-07 | Pfizer Limited | Substituted arylpyrazoles |
US7319108B2 (en) | 2004-01-25 | 2008-01-15 | Sanofi-Aventis Deutschland Gmbh | Aryl-substituted heterocycles, process for their preparation and their use as medicaments |
DE102004003812A1 (de) | 2004-01-25 | 2005-08-11 | Aventis Pharma Deutschland Gmbh | Arylsubstituierte Heterozyklen, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel |
US7297168B2 (en) | 2004-02-02 | 2007-11-20 | The Procter & Gamble Company | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof |
AU2005223483B2 (en) | 2004-03-18 | 2009-04-23 | Zoetis Llc | N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides |
US20070167426A1 (en) | 2004-06-02 | 2007-07-19 | Schering Corporation | Compounds for the treatment of inflammatory disorders and microbial diseases |
JO2540B1 (en) | 2004-07-01 | 2010-09-05 | اي.اي.ديو بونت دي نيمورز اند كومباني | Control factors for pests from invertebrate insects include a symbiotic mixture of anthranilamide |
MX2007002274A (es) | 2004-08-23 | 2007-05-07 | Lilly Co Eli | Agentes del receptor de histamina h3. preparacion y usos terapeuticos. |
JP2008513434A (ja) | 2004-09-23 | 2008-05-01 | ファイザー・プロダクツ・インク | トロンボポイエチン受容体アゴニスト |
AU2005297984B2 (en) | 2004-10-27 | 2009-11-12 | Daiichi Sankyo Company, Limited | Benzene compound having 2 or more substituents |
WO2006071940A2 (en) | 2004-12-23 | 2006-07-06 | Deciphera Pharmaceuticals, Llc | Enzyme modulators and treatments |
JP4966866B2 (ja) | 2005-01-14 | 2012-07-04 | エフ.ホフマン−ラ ロシュ アーゲー | mGluR5アンタゴニストとしてのチアゾール−4−カルボキサミド誘導体 |
EP1866293A1 (en) | 2005-03-31 | 2007-12-19 | UCB Pharma, S.A. | Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses |
US7608592B2 (en) | 2005-06-30 | 2009-10-27 | Virobay, Inc. | HCV inhibitors |
TWI402034B (zh) | 2005-07-28 | 2013-07-21 | Dow Agrosciences Llc | 具有被層狀液晶覆膜包覆之油球之水包油乳化劑之農用組成物 |
TW200800911A (en) | 2005-10-20 | 2008-01-01 | Biolipox Ab | Pyrazoles useful in the treatment of inflammation |
WO2007064316A1 (en) | 2005-11-30 | 2007-06-07 | Bristol-Myers Squibb Company | Bicyclic heterocycles as hiv integrase inhibitors |
JP2009523748A (ja) | 2006-01-18 | 2009-06-25 | シエナ ビオテク ソシエタ ペル アチオニ | α7ニコチン性アセチルコリン受容体の調節物質およびそれらの治療への使用 |
EP1983980A4 (en) | 2006-01-25 | 2010-05-05 | Synta Pharmaceuticals Corp | THIAZOL AND THIADIAZOL COMPOUNDS FOR USES IN RELATION TO INFLAMMATION AND IMMUNITY |
JP2010506599A (ja) * | 2006-05-22 | 2010-03-04 | ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | 第1流体と第2流体との間で成分を交換する方法、第1流体から第1成分を清浄する方法、血液の処理方法、流体処理装置、第1流体と第1及び第2成分を含む第2流体との間で成分を交換する装置、第1流体と第2流体との間で成分を交換する装置、血漿から血球を分離する方法 |
JP5642963B2 (ja) | 2006-06-30 | 2014-12-17 | スネシス ファーマシューティカルズ,インコーポレイティド | ピリジノニルpdk1阻害剤 |
US20090325956A1 (en) | 2006-10-13 | 2009-12-31 | Takahiko Taniguchi | Aromatic amine derivative and use thereof |
JP2010513519A (ja) | 2006-12-22 | 2010-04-30 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | キナーゼインヒビター活性を有するある種のピラゾリン誘導体 |
GB0701426D0 (en) | 2007-01-25 | 2007-03-07 | Univ Sheffield | Compounds and their use |
JP2008280341A (ja) | 2007-04-12 | 2008-11-20 | Sumitomo Chemical Co Ltd | ヒドラジド化合物およびその防除用途 |
WO2009011850A2 (en) | 2007-07-16 | 2009-01-22 | Abbott Laboratories | Novel therapeutic compounds |
KR20100095430A (ko) | 2007-11-02 | 2010-08-30 | 메틸진 인크. | 히스톤 탈아세틸화효소의 저해물질 |
WO2009076454A2 (en) | 2007-12-12 | 2009-06-18 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
EP2071950A1 (de) * | 2007-12-20 | 2009-06-24 | Bayer CropScience AG | Verfahren zur Authentizitätsprüfung von Pflanzenschutzmitteln mittels Isotopen |
US8278335B2 (en) | 2008-04-21 | 2012-10-02 | Merck Sharp & Dohme Corp. | Inhibitors of Janus kinases |
BRPI0915350A2 (pt) | 2008-06-13 | 2016-05-03 | Bayer Cropscience Ag | novas amidas e tioamidas heteroatômicas como pesticidas |
TW201004941A (en) * | 2008-07-16 | 2010-02-01 | Wyeth Corp | Alpha7 nicotinic acetylcholine receptor inhibitors |
ES2579085T3 (es) | 2008-07-17 | 2016-08-04 | Bayer Cropscience Ag | Compuestos heterocíclicos como pesticidas |
JP2010030970A (ja) | 2008-07-31 | 2010-02-12 | Bayer Cropscience Ag | 殺虫性ベンゼンジカルボキサミド誘導体 |
WO2010033360A1 (en) | 2008-09-19 | 2010-03-25 | 1/3 Absolute Science, Inc. | Methods of treating a botulinum toxin related condition in a subject |
US20110201649A1 (en) | 2008-09-19 | 2011-08-18 | Sumitomo Chemical Company, Limited | agricultural composition |
JP2012503623A (ja) * | 2008-09-24 | 2012-02-09 | ビーエーエスエフ ソシエタス・ヨーロピア | 無脊椎動物系害虫防除用ピラゾール化合物 |
MX2011004125A (es) | 2008-10-21 | 2011-05-19 | Metabolex Inc | Agonistas del receptor gpr120 de arilo y usos de los mismos. |
EP2184273A1 (de) * | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
CN101747276B (zh) | 2008-11-28 | 2011-09-07 | 中国中化股份有限公司 | 具有含氮五元杂环的醚类化合物及其应用 |
CN102264737A (zh) | 2008-12-23 | 2011-11-30 | 雅培制药有限公司 | 抗病毒化合物 |
NZ594163A (en) | 2009-02-11 | 2012-11-30 | Dow Agrosciences Llc | Pyranose derivatives of pestcidal 1,2,4-triazoles |
WO2010093849A2 (en) | 2009-02-13 | 2010-08-19 | Amgen Inc. | Phenylalanine amide derivatives useful for treating insulin-related diseases and conditions |
UA107791C2 (en) * | 2009-05-05 | 2015-02-25 | Dow Agrosciences Llc | Pesticidal compositions |
CN102438984A (zh) | 2009-05-19 | 2012-05-02 | 拜耳作物科学公司 | 杀虫用芳基吡咯啉 |
FI20095678A0 (fi) | 2009-06-16 | 2009-06-16 | Biotie Therapies Oy | Ureasubstituoituja sulfoniamidijohdannaisia |
UA110324C2 (en) | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
JP2012254939A (ja) | 2009-10-07 | 2012-12-27 | Astellas Pharma Inc | オキサゾール化合物 |
CN102573478B (zh) | 2009-10-12 | 2015-12-16 | 拜尔农作物科学股份公司 | 作为杀虫剂的1-(吡啶-3-基)-吡唑和1-(嘧啶-5-基)-吡唑 |
BR112012006239A2 (pt) | 2009-10-12 | 2015-09-08 | Bayer Cropscience Ag | amidas e tioamidas enquanto agentes pesticidas |
WO2011058578A1 (en) | 2009-11-13 | 2011-05-19 | Mehta Virendra J | Method and system for purifying water |
WO2011091153A1 (en) | 2010-01-25 | 2011-07-28 | Chdi, Inc. | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
WO2011101229A1 (en) | 2010-02-22 | 2011-08-25 | Syngenta Participations Ag | Dihydrofuran derivatives as insecticidal compounds |
EP2560966B1 (en) | 2010-03-30 | 2021-01-06 | Verseon International Corporation | Multisubstituted aromatic compounds as inhibitors of thrombin |
BR112012026530B1 (pt) * | 2010-04-16 | 2018-03-20 | Bayer Intellectual Property Gmbh | Compostos heterocíclicos como pesticidas, composição os compreendendo e suas utilizações, bem como método para controle de pragas de pragas |
EP2382865A1 (de) | 2010-04-28 | 2011-11-02 | Bayer CropScience AG | Synergistische Wirkstoffkombinationen |
EP2566865B1 (de) | 2010-05-05 | 2014-06-25 | Bayer Intellectual Property GmbH | Thiazolderivate als schädlingsbekämpfungsmittel |
MX2012015292A (es) | 2010-06-24 | 2013-05-30 | Gilead Sciences Inc | Pirazolo[1, 5]pirimidinas en la forma de agentes antivirales. |
RU2013103422A (ru) | 2010-06-28 | 2014-08-10 | Байер Интеллектчуал Проперти Гмбх | Гетероарил-замещенные пиридиновые соединения для применения в качестве пестицидов |
CN103080106A (zh) | 2010-07-06 | 2013-05-01 | 诺瓦提斯公司 | 用作激酶抑制剂的环醚化合物 |
EP2593447B1 (de) * | 2010-07-15 | 2016-08-17 | Bayer Intellectual Property GmbH | 3-pyridyl-heteroarylcarboxamidverbindungen als schädlingsbekämpfungsmittel |
US8604211B2 (en) | 2010-08-31 | 2013-12-10 | Dow AroSciecnes, LLC. | Pesticidal compositions |
JP2012082186A (ja) | 2010-09-15 | 2012-04-26 | Bayer Cropscience Ag | 殺虫性アリールピロリジン類 |
BR112013009823A2 (pt) | 2010-10-22 | 2016-07-05 | Bayer Ip Gmbh | novos compostos heterocíclicos como pesticidas |
MX343905B (es) * | 2010-11-03 | 2016-11-28 | Dow Agrosciences Llc | Composiciones pesticidas y procesos relacionados a las mismas. |
US8680121B2 (en) | 2010-11-03 | 2014-03-25 | Dow Agrosciences, Llc. | Pesticidal compositions and processes related thereto |
WO2012070114A1 (ja) | 2010-11-24 | 2012-05-31 | 塩野義製薬株式会社 | Npy y5受容体拮抗作用を有するスルファミド誘導体 |
WO2012102387A1 (ja) | 2011-01-27 | 2012-08-02 | 日産化学工業株式会社 | ピラゾール誘導体及び有害生物防除剤 |
JPWO2012108511A1 (ja) * | 2011-02-09 | 2014-07-03 | 日産化学工業株式会社 | ピラゾール誘導体および有害生物防除剤 |
JP2012188418A (ja) | 2011-02-22 | 2012-10-04 | Nissan Chem Ind Ltd | トリアゾ−ル誘導体及び有害生物防除剤 |
BR102012004142A2 (pt) | 2011-02-25 | 2015-04-07 | Dow Agrosciences Llc | Composições pesticidas e processos relacionados às mesmas |
JP2013107867A (ja) | 2011-04-21 | 2013-06-06 | Nissan Chem Ind Ltd | ピラゾール誘導体及び有害生物防除剤 |
EP2532661A1 (en) | 2011-06-10 | 2012-12-12 | Syngenta Participations AG | Novel insecticides |
EP2540718A1 (en) | 2011-06-29 | 2013-01-02 | Syngenta Participations AG. | Novel insecticides |
WO2013010946A2 (en) | 2011-07-15 | 2013-01-24 | Basf Se | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests i |
DK177393B1 (en) | 2011-09-02 | 2013-03-18 | Horsens Vand En As | Method and apparatus for extracting or concentrating carbonaceous compounds from a fluid |
JP2013082699A (ja) | 2011-09-30 | 2013-05-09 | Nissan Chem Ind Ltd | ピラゾール誘導体および有害生物防除剤 |
JP2013082704A (ja) | 2011-09-30 | 2013-05-09 | Nissan Chem Ind Ltd | チアゾール誘導体および有害生物防除剤 |
JP2013075871A (ja) | 2011-09-30 | 2013-04-25 | Nissan Chem Ind Ltd | チアゾール誘導体および有害生物防除剤 |
KR20140085527A (ko) | 2011-10-26 | 2014-07-07 | 다우 아그로사이언시즈 엘엘씨 | 살충 조성물 및 그와 관련된 방법 |
CN104010505B (zh) | 2011-10-26 | 2017-03-15 | 陶氏益农公司 | 杀虫组合物和与其相关的方法 |
JP2013129653A (ja) | 2011-11-22 | 2013-07-04 | Nissan Chem Ind Ltd | トリアゾ−ル誘導体および有害生物防除剤 |
JP2013129651A (ja) | 2011-11-22 | 2013-07-04 | Nissan Chem Ind Ltd | チアゾール誘導体および有害生物防除剤 |
WO2013156431A1 (en) | 2012-04-17 | 2013-10-24 | Syngenta Participations Ag | Pesticidally active pyridyl- and pyrimidyl- substituted thiazole and thiadiazole derivatives |
WO2013156433A1 (en) | 2012-04-17 | 2013-10-24 | Syngenta Participations Ag | Insecticidally active thiazole derivatives |
CA2870090A1 (en) | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
MX349113B (es) | 2012-06-04 | 2017-07-12 | Dow Agrosciences Llc | Procesos para producir ciertos 2-piridin-3-il) tiazoles. |
BR112014029957B1 (pt) | 2012-06-04 | 2019-01-15 | Dow Agrosciences Llc | processos para produzir determinados 2-(piridina-3-il)tiazóis |
-
2013
- 2013-03-07 CA CA2870090A patent/CA2870090A1/en not_active Abandoned
- 2013-03-07 CN CN201610143440.1A patent/CN105732579A/zh active Pending
- 2013-03-07 EP EP13782228.4A patent/EP2852284A4/en not_active Withdrawn
- 2013-03-07 WO PCT/US2013/029615 patent/WO2013162716A2/en active Application Filing
- 2013-03-07 WO PCT/US2013/029608 patent/WO2013162715A2/en active Application Filing
- 2013-03-07 CN CN201610143950.9A patent/CN105732580B/zh not_active Expired - Fee Related
- 2013-03-07 RU RU2014147737A patent/RU2627654C2/ru not_active IP Right Cessation
- 2013-03-07 RU RU2017126178A patent/RU2651369C1/ru not_active IP Right Cessation
- 2013-03-07 JP JP2015508957A patent/JP6463670B2/ja not_active Expired - Fee Related
- 2013-03-07 AP AP2014008072A patent/AP2014008072A0/xx unknown
- 2013-03-07 JP JP2015508958A patent/JP6189937B2/ja not_active Expired - Fee Related
- 2013-03-07 BR BR112014026746A patent/BR112014026746A2/pt not_active Application Discontinuation
- 2013-03-07 CA CA2871696A patent/CA2871696A1/en not_active Abandoned
- 2013-03-07 US US13/788,736 patent/US20130291227A1/en not_active Abandoned
- 2013-03-07 UA UAA201412716A patent/UA115144C2/uk unknown
- 2013-03-07 EP EP13782446.2A patent/EP2840898A4/en not_active Withdrawn
- 2013-03-07 KR KR1020147032872A patent/KR20150017709A/ko not_active Application Discontinuation
- 2013-03-07 KR KR1020147032871A patent/KR20150013586A/ko not_active Application Discontinuation
- 2013-03-07 BR BR112014026526A patent/BR112014026526A2/pt not_active Application Discontinuation
- 2013-03-07 MA MA37571A patent/MA37571A1/fr unknown
- 2013-03-07 NZ NZ715920A patent/NZ715920A/en not_active IP Right Cessation
- 2013-03-07 BR BR122014028247A patent/BR122014028247A2/pt not_active Application Discontinuation
- 2013-03-07 CN CN201380033110.1A patent/CN104822266B/zh not_active Expired - Fee Related
- 2013-03-07 AU AU2013252946A patent/AU2013252946A1/en not_active Abandoned
- 2013-03-07 MX MX2014013069A patent/MX2014013069A/es unknown
- 2013-03-07 NZ NZ700595A patent/NZ700595A/en not_active IP Right Cessation
- 2013-03-07 MX MX2014013071A patent/MX2014013071A/es unknown
- 2013-03-07 CN CN201380032905.0A patent/CN104378986B/zh not_active Expired - Fee Related
- 2013-03-07 RU RU2014147690A patent/RU2623233C2/ru not_active IP Right Cessation
- 2013-03-07 US US13/788,850 patent/US8901153B2/en not_active Expired - Fee Related
- 2013-03-07 NZ NZ700590A patent/NZ700590A/en not_active IP Right Cessation
- 2013-03-07 AP AP2014008071A patent/AP2014008071A0/xx unknown
- 2013-03-07 MA MA37572A patent/MA37572B1/fr unknown
- 2013-03-12 AU AU2013201628A patent/AU2013201628B2/en active Active
- 2013-03-12 AU AU2013201636A patent/AU2013201636B2/en not_active Ceased
- 2013-04-26 TW TW102115076A patent/TWI594994B/zh not_active IP Right Cessation
- 2013-04-26 TW TW105144221A patent/TWI630202B/zh not_active IP Right Cessation
- 2013-04-26 TW TW102115077A patent/TWI574955B/zh not_active IP Right Cessation
- 2013-04-26 TW TW106120597A patent/TWI622585B/zh not_active IP Right Cessation
- 2013-04-26 AR ARP130101436A patent/AR090868A1/es unknown
- 2013-04-26 AR ARP130101435A patent/AR090867A1/es unknown
-
2014
- 2014-10-23 IL IL235322A patent/IL235322A0/en unknown
- 2014-10-24 PH PH12014502398A patent/PH12014502398B1/en unknown
- 2014-10-24 PH PH12014502397A patent/PH12014502397A1/en unknown
- 2014-10-26 IL IL235327A patent/IL235327A/en active IP Right Grant
- 2014-10-27 CO CO14236460A patent/CO7111287A2/es unknown
- 2014-10-27 CL CL2014002900A patent/CL2014002900A1/es unknown
- 2014-10-27 CO CO14236459A patent/CO7111285A2/es unknown
- 2014-10-27 CL CL2014002899A patent/CL2014002899A1/es unknown
- 2014-11-25 ZA ZA2014/08647A patent/ZA201408647B/en unknown
- 2014-11-25 ZA ZA2014/08645A patent/ZA201408645B/en unknown
-
2015
- 2015-03-19 HK HK15102814.3A patent/HK1202225A1/xx not_active IP Right Cessation
- 2015-06-03 AU AU2015203318A patent/AU2015203318B2/en active Active
- 2015-08-03 US US14/816,295 patent/US9591857B2/en not_active Expired - Fee Related
- 2015-10-26 HK HK15110496.1A patent/HK1209590A1/xx unknown
-
2017
- 2017-01-12 IL IL250093A patent/IL250093A0/en unknown
- 2017-02-02 JP JP2017017645A patent/JP2017137308A/ja active Pending
- 2017-11-28 JP JP2017227417A patent/JP2018058872A/ja not_active Withdrawn
Cited By (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150166531A1 (en) * | 2010-11-03 | 2015-06-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US8815271B2 (en) | 2010-11-03 | 2014-08-26 | Dow Agrosciences, Llc. | Pesticidal compositions and processes related thereto |
US9422278B2 (en) * | 2010-11-03 | 2016-08-23 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US10165775B2 (en) | 2011-10-26 | 2019-01-01 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9655365B2 (en) | 2011-10-26 | 2017-05-23 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US20140213448A1 (en) * | 2012-04-27 | 2014-07-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US8901153B2 (en) * | 2012-04-27 | 2014-12-02 | Dow Agrosciences, Llc. | Pesticidal compositions and processes related thereto |
US9282739B2 (en) * | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9591857B2 (en) | 2012-04-27 | 2017-03-14 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US20130288893A1 (en) * | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9126974B2 (en) | 2013-10-17 | 2015-09-08 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9174962B2 (en) | 2013-10-17 | 2015-11-03 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9862702B2 (en) | 2013-10-17 | 2018-01-09 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9796682B2 (en) | 2013-10-17 | 2017-10-24 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9085564B2 (en) | 2013-10-17 | 2015-07-21 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9102654B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9102655B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9108946B2 (en) | 2013-10-17 | 2015-08-18 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9723839B2 (en) | 2013-10-17 | 2017-08-08 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9901095B2 (en) | 2013-10-17 | 2018-02-27 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9908864B2 (en) | 2013-10-17 | 2018-03-06 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9670164B2 (en) | 2013-10-17 | 2017-06-06 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9670178B2 (en) | 2013-10-17 | 2017-06-06 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9661849B2 (en) | 2013-10-17 | 2017-05-30 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9029554B1 (en) * | 2013-10-17 | 2015-05-12 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9044017B2 (en) | 2013-10-17 | 2015-06-02 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9199942B2 (en) | 2013-10-17 | 2015-12-01 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9988356B2 (en) | 2013-10-17 | 2018-06-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US10315999B2 (en) | 2013-10-17 | 2019-06-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9255082B2 (en) | 2013-10-17 | 2016-02-09 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9255083B2 (en) | 2013-10-17 | 2016-02-09 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9580405B2 (en) | 2013-10-17 | 2017-02-28 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9260396B2 (en) | 2013-10-17 | 2016-02-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US20150112073A1 (en) * | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9550751B2 (en) | 2013-10-17 | 2017-01-24 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9540342B2 (en) | 2013-10-17 | 2017-01-10 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9447048B2 (en) | 2013-10-17 | 2016-09-20 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9433215B2 (en) | 2013-10-17 | 2016-09-06 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9434712B2 (en) | 2013-10-17 | 2016-09-06 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9414594B2 (en) | 2013-10-17 | 2016-08-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9155304B2 (en) | 2013-10-22 | 2015-10-13 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9523100B2 (en) | 2013-10-22 | 2016-12-20 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9801376B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9808008B2 (en) * | 2013-10-22 | 2017-11-07 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9445597B2 (en) | 2013-10-22 | 2016-09-20 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9295258B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9474276B2 (en) | 2013-10-22 | 2016-10-25 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9491944B2 (en) | 2013-10-22 | 2016-11-15 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9497967B2 (en) | 2013-10-22 | 2016-11-22 | Doe AgroSciences LLC | Synergistic pesticidal compositions and related methods |
US9497966B2 (en) * | 2013-10-22 | 2016-11-22 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9788546B2 (en) | 2013-10-22 | 2017-10-17 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9801383B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9295260B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9282740B2 (en) | 2013-10-22 | 2016-03-15 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9549560B2 (en) | 2013-10-22 | 2017-01-24 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9788545B2 (en) | 2013-10-22 | 2017-10-17 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9137998B2 (en) | 2013-10-22 | 2015-09-22 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9144241B2 (en) | 2013-10-22 | 2015-09-29 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
USRE48057E1 (en) | 2013-10-22 | 2020-06-23 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US20150111743A1 (en) * | 2013-10-22 | 2015-04-23 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US20150111732A1 (en) * | 2013-10-22 | 2015-04-23 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9149040B2 (en) | 2013-10-22 | 2015-10-06 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9326508B2 (en) | 2014-01-10 | 2016-05-03 | Valent Biosciences Corporation | (S)-3′-methyl-abscisic acid and esters thereof |
WO2015106050A1 (en) * | 2014-01-10 | 2015-07-16 | Valent Biosciences Corporation | (s)-3'-methyl-abscisic acid and esters thereof |
US9029556B1 (en) | 2014-07-31 | 2015-05-12 | Dow Argosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9580403B2 (en) | 2014-07-31 | 2017-02-28 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9611247B2 (en) | 2014-07-31 | 2017-04-04 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9199964B1 (en) | 2014-07-31 | 2015-12-01 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9029555B1 (en) | 2014-07-31 | 2015-05-12 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9371310B2 (en) | 2014-07-31 | 2016-06-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9840490B2 (en) | 2014-07-31 | 2017-12-12 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9573931B2 (en) | 2014-07-31 | 2017-02-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US10035786B2 (en) | 2014-07-31 | 2018-07-31 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
US9255081B1 (en) | 2014-07-31 | 2016-02-09 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9249122B1 (en) | 2014-07-31 | 2016-02-02 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9115115B1 (en) | 2014-08-19 | 2015-08-25 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US10005758B2 (en) | 2014-08-19 | 2018-06-26 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9522900B2 (en) | 2014-08-19 | 2016-12-20 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9809570B2 (en) | 2014-08-19 | 2017-11-07 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9024031B1 (en) | 2014-08-19 | 2015-05-05 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9156813B1 (en) | 2014-09-12 | 2015-10-13 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9663489B2 (en) | 2014-09-12 | 2017-05-30 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9422265B2 (en) | 2014-09-12 | 2016-08-23 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
US9896430B2 (en) | 2014-09-12 | 2018-02-20 | Dow Agrosciences Llc | Process for the preparation of 3-(3-CHLORO-1H-pyrazol-1-yl)pyridine |
US9085552B1 (en) | 2014-09-12 | 2015-07-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
WO2017034571A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034577A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034573A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034570A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034572A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034579A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017034569A1 (en) * | 2015-08-27 | 2017-03-02 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017086972A1 (en) * | 2015-11-19 | 2017-05-26 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
WO2017086971A1 (en) * | 2015-11-19 | 2017-05-26 | Dow Agrosciences Llc | Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto |
US20190045784A1 (en) * | 2016-02-26 | 2019-02-14 | Basf Se | Fungicidal mixtures comprising fluxapyroxad |
WO2018039028A1 (en) * | 2016-08-26 | 2018-03-01 | Dow Agrosciences Llc | Foliar applications for controlling lepidopteran pests for fruits and/or fruit trees |
WO2018125820A1 (en) * | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US10233155B2 (en) | 2016-12-29 | 2019-03-19 | Dow Agrosciences Llc | Processes for the preparation of pesticide compounds |
US10100033B2 (en) | 2016-12-29 | 2018-10-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US10894783B2 (en) | 2018-06-08 | 2021-01-19 | Dow Agrosciences Llc | Molecule having pesticidal utility, and compositions, and processes, related thereto |
US11691961B2 (en) | 2018-06-08 | 2023-07-04 | Corteva Agriscience Llc | Molecule having pesticidal utility, and compositions, and processes, related thereto |
US11939313B2 (en) | 2018-06-08 | 2024-03-26 | Corteva Agriscience Llc | Molecule having pesticidal utility, and compositions, and processes, related thereto |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10165775B2 (en) | Pesticidal compositions and processes related thereto | |
US9591857B2 (en) | Pesticidal compositions and processes related thereto | |
US9422278B2 (en) | Pesticidal compositions and processes related thereto | |
US9282739B2 (en) | Pesticidal compositions and processes related thereto | |
US9708288B2 (en) | Pesticidal compositions and processes related thereto | |
AU2015201987B2 (en) | Pesticidal compositions and processes related thereto | |
OA16403A (en) | Pesticidal compositions and processes related thereto. | |
NZ623298B2 (en) | Pesticidal compositions and processes related thereto |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: DOW AGROSCIENCES LLC, INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BUYSSE, ANN M;NIYAZ, NOORMOHAMED M;ZHANG, YU;AND OTHERS;REEL/FRAME:032953/0177 Effective date: 20130418 |
|
AS | Assignment |
Owner name: DOW AGROSCIENCES LLC, INDIANA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BUYSSE, ANN M;NIYAZ, NOORMOHAMED M;ZHANG, YU;AND OTHERS;REEL/FRAME:032970/0206 Effective date: 20130418 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO PAY ISSUE FEE |