BRPI9909860B8
(pt)
*
|
1998-04-21 |
2021-05-25 |
Amgen Res Munich Gmbh |
polipeptídeo multifuncional de cadeia simples, polinucleotídeo, vetor, célula procariótica, de levedura ou unicelular, composição, usos de polipeptídeo e polinucleotídeo e métodos para preparo do referido polipeptídeo e para identificação de ativadores ou inibidores de ativação ou estimulação das células t
|
DK1176981T3
(da)
|
1999-05-07 |
2006-04-10 |
Genentech Inc |
Behandling af autoimmune sygdomme med antagonister som binder til B celleoverflademarkörer
|
US8383081B2
(en)
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
US7074403B1
(en)
|
1999-06-09 |
2006-07-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
EP1543839B1
(fr)
*
|
1999-06-09 |
2017-09-20 |
Immunomedics, Inc. |
Immunothérapie de troubles auto-immuns à l'aide d'anticorps ciblant les cellules B
|
DE19962583A1
(de)
*
|
1999-12-23 |
2001-06-28 |
Mueller Hermelink Hans Konrad |
Antikörper gegen Plasmazellen
|
EP1334188B1
(fr)
*
|
2000-11-07 |
2006-08-30 |
City of Hope |
Cellules immunitaires specifiques a cd19 redirigees
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
CA2522586C
(fr)
*
|
2003-05-31 |
2017-02-21 |
Micromet Ag |
Compositions pharmaceutiques comprenant des constructions d'anticorps anti-cd3, anti-cd19 bispecifiques pour le traitement de troubles associes aux lymphocytes b
|
AU2004242845B2
(en)
|
2003-05-31 |
2011-06-02 |
Amgen Research (Munich) Gmbh |
Human-anti-human CD3 binding molecules
|
AU2004291026A1
(en)
|
2003-06-06 |
2005-06-02 |
Medimmune, Llc |
Use of EphA4 and modulator of EphA4 for diagnosis, treatment and prevention of cancer
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
EP2216342B1
(fr)
*
|
2003-07-31 |
2015-04-22 |
Immunomedics, Inc. |
Anticorps anti-CD19
|
BRPI0415457A
(pt)
|
2003-10-16 |
2006-12-05 |
Micromet Ag |
constructo de ligação especìfico de cd3 citotoxicamente ativo, seu processo de produção, composição compreendendo o mesmo, seqüência de ácido nucléico, vetor, hospedeiro, seus usos na preparação de uma composição farmacêutica e kit compreendendo os mesmo
|
DK1691833T3
(da)
*
|
2003-11-28 |
2010-05-03 |
Micromet Ag |
Præparater der omfatter polypeptider
|
US7235641B2
(en)
*
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
US8883160B2
(en)
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
DK1716178T3
(da)
|
2004-02-16 |
2010-09-20 |
Micromet Ag |
Mindre immunogene bindingsmolekyler
|
JP2008507294A
(ja)
|
2004-07-26 |
2008-03-13 |
ダウ グローバル テクノロジーズ インコーポレイティド |
菌株遺伝子操作による改善されたタンパク質発現のための方法
|
CA2585717A1
(fr)
|
2004-10-27 |
2006-05-04 |
Medimmune Inc. |
Modulation d'une specificite d'anticorps par adaptation sur mesure de son affinite a un antigene apparente
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
UA94403C2
(ru)
|
2005-04-18 |
2011-05-10 |
Микромет Аг |
Человеческое моноклональное антитело, которое нейтрализует gm-csf
|
DK1874821T3
(da)
|
2005-04-26 |
2013-07-08 |
Trion Pharma Gmbh |
Kombination af antistoffer med glykokortikoider til behandling af kræft
|
JP5215180B2
(ja)
|
2005-06-20 |
2013-06-19 |
メダレックス インコーポレーティッド |
Cd19抗体およびその使用法
|
BRPI0615026A8
(pt)
*
|
2005-08-19 |
2018-03-06 |
Abbott Lab |
imunoglobulina de domínio variável duplo e seus usos
|
AU2006301492B2
(en)
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
RS53905B1
(en)
|
2005-12-16 |
2015-08-31 |
Amgen Research (Munich) Gmbh |
METHODS AND TREATMENTS FOR TUMOR DISEASE
|
PT1976880T
(pt)
|
2005-12-21 |
2016-09-28 |
Amgen Res (Munich) Gmbh |
Composições farmacêuticas com resistência a cea solúvel
|
SG170051A1
(en)
*
|
2006-03-02 |
2011-04-29 |
Antitope Ltd |
T cell assays
|
ME01786B
(me)
|
2006-08-14 |
2014-09-20 |
Xencor Inc |
Optimizovana antitela usmerena na cd19
|
WO2008031056A2
(fr)
*
|
2006-09-08 |
2008-03-13 |
Medimmune, Llc |
Anticorps anti-cd19 humanisés, et leur utilisation dans le traitement de l'oncologie, de la transplantation et de la maladie auto-immune
|
EP2155788B1
(fr)
*
|
2007-04-03 |
2012-06-27 |
Micromet AG |
Éléments de liaison bispécifiques spécifiques d'espèces croisées
|
AU2008234020B2
(en)
|
2007-04-03 |
2013-02-07 |
Amgen Research (Munich) Gmbh |
Cross-species-specific CD3-epsilon binding domain
|
PL2155783T5
(pl)
†
|
2007-04-03 |
2023-03-13 |
Amgen Research (Munich) Gmbh |
Swoista międzygatunkowo domena wiążąca CD3epsilon
|
JP5444553B2
(ja)
|
2007-04-27 |
2014-03-19 |
フェネックス インコーポレイテッド |
微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および/または質が改善されている特定の株を同定する方法
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
LT3327026T
(lt)
|
2007-07-09 |
2019-11-11 |
Genentech Inc |
Disulfidinio ryšio redukcijos prevencija rekombinantinių polipeptidų gaminimo metu
|
WO2009018453A1
(fr)
*
|
2007-07-31 |
2009-02-05 |
Lifescan, Inc. |
Différenciation de cellules souches embryonnaires humaines
|
US20090155275A1
(en)
*
|
2007-07-31 |
2009-06-18 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
JP5727786B2
(ja)
*
|
2007-10-19 |
2015-06-03 |
シアトル ジェネティクス,インコーポレーテッド |
Cd19結合性物質およびその使用
|
EP2225275A4
(fr)
*
|
2007-11-28 |
2013-04-03 |
Medimmune Llc |
Formulation de protéine
|
BRPI0919840B1
(pt)
*
|
2008-10-01 |
2023-02-28 |
Amgen Research (Munich) Gmbh |
Molécula de anticorpo de cadeia única biespecífica, seu uso, e composição farmacêutica que a compreende
|
EP2352765B1
(fr)
|
2008-10-01 |
2018-01-03 |
Amgen Research (Munich) GmbH |
Anticorps monocaténaire bispécifique à domaine unique, spécifique d'espèces croisées
|
PT2356153T
(pt)
|
2008-10-01 |
2016-07-15 |
Amgen Res (Munich) Gmbh |
Anticorpo biespecífico, de cadeia única, amepxcd3, específico interespécies
|
DK2352763T4
(da)
|
2008-10-01 |
2022-10-17 |
Amgen Res Munich Gmbh |
Bispecifikke enkeltkædede antistoffer med specificitet for højmolekylære målantigener
|
ES2558434T3
(es)
*
|
2008-11-07 |
2016-02-04 |
Amgen Research (Munich) Gmbh |
Tratamiento de leucemia linfoblástica aguda
|
EP2918604B1
(fr)
*
|
2008-11-07 |
2017-12-20 |
Amgen Research (Munich) GmbH |
Traitement de la leucémie lymphoblastique aiguë pédiatrique
|
EP2389362B1
(fr)
|
2009-01-21 |
2019-12-11 |
Oryzon Genomics, S.A. |
Dérivés de phénylcyclopropylamine et leur utilisation médicale
|
US9676845B2
(en)
*
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US20110002931A1
(en)
|
2009-06-23 |
2011-01-06 |
Alexion Pharmaceuticals, Inc. |
Bispecific antibodies that bind to complement proteins
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
WO2011035941A1
(fr)
|
2009-09-25 |
2011-03-31 |
Oryzon Genomics S.A. |
Inhibiteurs de déméthylase-1 spécifique de la lysine et leur utilisation
|
US8946296B2
(en)
|
2009-10-09 |
2015-02-03 |
Oryzon Genomics S.A. |
Substituted heteroaryl- and aryl-cyclopropylamine acetamides and their use
|
RS54655B2
(sr)
|
2009-10-27 |
2021-04-29 |
Amgen Res Munich Gmbh |
Dozni režim za primenu cd19xcd3 bispecifičnog antitela
|
CA2781682A1
(fr)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Anticorps plurispecifiques, analogues d'anticorps, compositions et procedes
|
TW201125583A
(en)
*
|
2009-12-23 |
2011-08-01 |
Bioalliance Cv |
Anti-EpCAM antibodies that induce apoptosis of cancer cells and methods using same
|
US9186337B2
(en)
|
2010-02-24 |
2015-11-17 |
Oryzon Genomics S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae
|
WO2011106574A2
(fr)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Inhibiteurs destinés à une utilisation antivirale
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
EP3133059A1
(fr)
|
2010-04-19 |
2017-02-22 |
Oryzon Genomics, S.A. |
Inhibiteurs de déméthylase-1 spécifiques de la lysine et leur utilisation
|
RU2636461C2
(ru)
|
2010-05-03 |
2017-11-23 |
Дженентек, Инк. |
Композиции и способы для диагностики и лечения опухоли
|
JP5636091B2
(ja)
|
2010-05-05 |
2014-12-03 |
ウニベルジテート バイロイト |
癌治療に用いるためのコンブレタスタチン類似体
|
CN102250245B
(zh)
*
|
2010-05-27 |
2014-05-14 |
四川大学 |
抗b细胞淋巴瘤的双特异性抗体及其用途
|
US20130123367A1
(en)
|
2010-07-28 |
2013-05-16 |
Medizinische Universitat Wien |
Vinylogous chalcone derivatives and their medical use
|
WO2012013728A1
(fr)
|
2010-07-29 |
2012-02-02 |
Oryzon Genomics S.A. |
Inhibiteurs de déméthylase lsd1 base d'aryclcyclopropylamine et leur utilisation médicale
|
WO2012016227A2
(fr)
|
2010-07-29 |
2012-02-02 |
Xencor, Inc. |
Anticorps dont les points isoélectriques sont modifiés
|
US9006449B2
(en)
|
2010-07-29 |
2015-04-14 |
Oryzon Genomics, S.A. |
Cyclopropylamine derivatives useful as LSD1 inhibitors
|
US9061966B2
(en)
|
2010-10-08 |
2015-06-23 |
Oryzon Genomics S.A. |
Cyclopropylamine inhibitors of oxidases
|
PL3018145T3
(pl)
|
2010-10-27 |
2018-09-28 |
Amgen Research (Munich) Gmbh |
Środki i sposoby leczenia chłoniaka rozlanego z dużych komórek B (DLBCL)
|
SG190174A1
(en)
|
2010-11-10 |
2013-07-31 |
Amgen Res Munich Gmbh |
Prevention of adverse effects caused by cd3 specific binding domains
|
EP2640750A1
(fr)
|
2010-11-16 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Agents et méthodes de traitement de maladies qui sont corrélées à une expression de bcma
|
WO2012072713A2
(fr)
|
2010-11-30 |
2012-06-07 |
Oryzon Genomics, S.A. |
Inhibiteurs de la déméthylase spécifique de la lysine pour des maladies et troubles liés aux flaviviridés
|
EP3981395A1
(fr)
|
2011-02-08 |
2022-04-13 |
Oryzon Genomics, S.A. |
Inhibiteurs de lysine déméthylase pour des troubles myéloprolifératifs
|
CA2827170A1
(fr)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Complexes plurispecifiques monovalents et multivalents et leurs utilisations
|
WO2012146394A1
(fr)
*
|
2011-04-28 |
2012-11-01 |
Amgen Research (Munich) Gmbh |
Régime posologique pour l'administration d'un anticorps bispécifique cd19xcd3 à des patients à risque d'éventuels effets indésirables
|
BR122016016837A2
(pt)
|
2011-05-21 |
2019-08-27 |
Macrogenics Inc |
moléculas de ligação a cd3; anticorpos de ligação a cd3; composições farmacêuticas; e usos da molécula de ligação a cd3
|
WO2012162561A2
(fr)
|
2011-05-24 |
2012-11-29 |
Zyngenia, Inc. |
Complexes plurispécifiques multivalents et monovalents, et leurs utilisations
|
PL2718320T3
(pl)
|
2011-06-10 |
2018-06-29 |
Medimmune Limited |
Cząsteczki wiążące przeciwko PSL Pseudomonas i ich zastosowanie
|
HUE058350T2
(hu)
*
|
2011-08-16 |
2022-07-28 |
Morphosys Ag |
Kombinációs terápia, CD19 elleni ellenanyag és nitrogénmustár alkalmazásával
|
DE202012012998U1
(de)
|
2011-08-31 |
2014-06-13 |
Daniel Elias |
Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
|
WO2013041687A1
(fr)
|
2011-09-23 |
2013-03-28 |
Amgen Research (Munich) Gmbh |
Molécules de liaison bispécifiques pour 5t4 et cd3
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
AU2012324803B9
(en)
|
2011-10-20 |
2017-08-24 |
Oryzon Genomics, S.A. |
(hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
|
JP6046154B2
(ja)
|
2011-10-20 |
2016-12-14 |
オリソン ヘノミクス エセ. アー. |
Lsd1阻害剤としての(ヘテロ)アリールシクロプロピルアミン化合物
|
CN104136042B
(zh)
|
2011-11-07 |
2017-08-18 |
米迪缪尼有限公司 |
使用抗假单胞菌Psl和PcrV结合分子的联合治疗
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
US9192664B2
(en)
|
2011-12-05 |
2015-11-24 |
Immunomedics, Inc. |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis
|
US9757458B2
(en)
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
RU2693264C2
(ru)
*
|
2012-02-03 |
2019-07-01 |
Ф.Хоффман-Ля Рош Аг |
Молекулы биспецифических антител и т-клетки, трансфецированные антигеном, и их применение в медицине
|
WO2013126712A1
(fr)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Topicompositions et procédés pour produire une population de lymphocytes t tenaces utiles dans le traitement du cancer
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
EP2820047B1
(fr)
|
2012-03-01 |
2018-04-25 |
Amgen Research (Munich) GmbH |
Molécules de liaison à un polypeptide à longue durée de vie
|
CN103382223B
(zh)
|
2012-04-01 |
2015-06-10 |
上海益杰生物技术有限公司 |
针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
|
WO2014004549A2
(fr)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Protéines de liaison anti-mésothéline
|
EA201590208A1
(ru)
|
2012-07-13 |
2015-11-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Усиление активности т-клеток car путем совместного введения биспецифического антитела
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
EP2885002A4
(fr)
|
2012-08-14 |
2016-04-20 |
Ibc Pharmaceuticals Inc |
Anticorps bispécifiques redirigés contre des cellules t pour le traitement de maladies
|
US10131712B2
(en)
|
2012-08-14 |
2018-11-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
AR093297A1
(es)
|
2012-10-31 |
2015-05-27 |
Amgen Res (Munich) Gmbh |
Formulacion liquida que comprende un compuesto neutralizante de gm-csf
|
US9833410B2
(en)
|
2012-10-31 |
2017-12-05 |
Takeda Gmbh |
Lyophilized formulation comprising GM-CSF neutralizing compound
|
CN103833852A
(zh)
*
|
2012-11-23 |
2014-06-04 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
US9107960B2
(en)
|
2012-12-13 |
2015-08-18 |
Immunimedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
CA3177936A1
(fr)
|
2012-12-13 |
2014-06-19 |
Immunomedics, Inc. |
Dosages d'immuno-conjugues d'anticorps et de sn-38 pour ameliorer l'efficacite et reduire la toxicite
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
EP2943511B1
(fr)
|
2013-01-14 |
2019-08-07 |
Xencor, Inc. |
Nouvelles protéines hétérodimères
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
WO2014113510A1
(fr)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Elimination rapide de complexes antigéniques à l'aide de nouveaux anticorps
|
CN103965359B
(zh)
*
|
2013-01-24 |
2016-08-03 |
上海市肿瘤研究所 |
抗上皮细胞粘附分子和t细胞抗原的双特异性抗体
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
US9486475B2
(en)
|
2013-02-08 |
2016-11-08 |
Amgen Research (Munich) Gmbh |
PPS for the prevention of potential adverse effects caused by CD3 specific binding domains
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
US20160015749A1
(en)
|
2013-03-05 |
2016-01-21 |
Baylor College Of Medicine |
Engager cells for immunotherapy
|
CN105407902A
(zh)
|
2013-03-05 |
2016-03-16 |
贝勒医学院 |
溶瘤病毒
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
WO2014145907A1
(fr)
|
2013-03-15 |
2014-09-18 |
Xencor, Inc. |
Ciblage des lymphocytes t avec des protéines hétérodimères
|
WO2014140368A1
(fr)
|
2013-03-15 |
2014-09-18 |
Amgen Research (Munich) Gmbh |
Constructions d'anticorps pour m2 et cd3 de grippe
|
US9561291B2
(en)
*
|
2013-03-15 |
2017-02-07 |
Imre Kovesdi |
Methods of targeting T-cells to tumors
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
CA2907181C
(fr)
|
2013-03-15 |
2023-10-17 |
Viktor Roschke |
Complexes multispecifiques multivalents et monovalents et leurs utilisations
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
BR112015022978A8
(pt)
*
|
2013-03-15 |
2018-01-23 |
Memorial Sloan Kettering Cancer Center |
tecnologias de multimerização
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
SI2970449T1
(sl)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Enoverižne vezavne molekule, ki vsebujejo N-terminalni ABP
|
CN107460201A
(zh)
*
|
2013-05-08 |
2017-12-12 |
科济生物医药(上海)有限公司 |
编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞
|
WO2014180577A1
(fr)
*
|
2013-05-10 |
2014-11-13 |
Numab Ag |
Constructions bispécifiques et leur utilisation dans le traitement de plusieurs maladies
|
TR201904121T4
(tr)
*
|
2013-07-09 |
2019-04-22 |
The Government Of The United States As Represented By The Secretary Of The Dept Of Health And Human |
İnsan bispesifik egfrviii antikoru birleştirme molekülleri.
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
CN104342453A
(zh)
*
|
2013-08-06 |
2015-02-11 |
深圳先进技术研究院 |
含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
EP3889178A1
(fr)
|
2013-08-30 |
2021-10-06 |
Takeda GmbH |
Anticorps neutralisant le gm-csf destiné à être utilisé dans le traitement de la polyarthrite rhumatoïde ou comme analgésique
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
JP6502931B2
(ja)
|
2013-10-11 |
2019-04-17 |
アメリカ合衆国 |
Tem8抗体およびその使用
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
WO2015103549A1
(fr)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Anticorps neutralisants dirigés contre la env du vih-1 et leur utilisation
|
CN106132436B
(zh)
*
|
2014-02-21 |
2021-06-15 |
Ibc药品公司 |
通过诱导对trop-2表达细胞的免疫应答的疾病疗法
|
US9139649B2
(en)
|
2014-02-25 |
2015-09-22 |
Immunomedics, Inc. |
Humanized anti-CD22 antibody
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
JP6775422B2
(ja)
|
2014-03-28 |
2020-10-28 |
ゼンコー・インコーポレイテッドXencor、 Inc. |
Cd38及びcd3に結合する二重特異性抗体
|
RU2577226C2
(ru)
*
|
2014-04-10 |
2016-03-10 |
Общество с ограниченной ответственностью, "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Способ получения биспецифических антител против cd3*cd19 формата флексибоди в клетках млекопитающих
|
RU2568910C2
(ru)
*
|
2014-04-18 |
2015-11-20 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Фармацевтические композиции на основе флексибоди против cd3*cd19 для лечения в-клеточных заболеваний
|
CN105017422A
(zh)
*
|
2014-04-30 |
2015-11-04 |
山东百因制药技术有限公司 |
一种抗cd3/抗cd19双特异性抗体及其应用
|
KR102385802B1
(ko)
|
2014-05-07 |
2022-04-13 |
다케다 야쿠힝 고교 가부시키가이샤 |
Gm-csf 중화 화합물을 포함하는 액체 제제
|
WO2015172341A1
(fr)
*
|
2014-05-14 |
2015-11-19 |
上海市肿瘤研究所 |
Anticorps bispecifique dirige contre le glypicane 3 et un antigene de lymphocyte t
|
EP2947460A1
(fr)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Thérapie personnalisée de cancer associé à une inflammation à l'aide de procédés d'évaluation de la susceptibilité d'un sujet pour le traitement avec des antagonistes/inhibiteurs EGFR
|
WO2015181683A1
(fr)
|
2014-05-30 |
2015-12-03 |
Amgen Research (Munich) Gmbh |
Stratification du risque pour patients souffrant de leucémie aiguë lymphoblastique à précurseurs b
|
JP2017520575A
(ja)
|
2014-07-01 |
2017-07-27 |
ファイザー・インク |
二重特異的ヘテロ二量体ダイアボディおよびその使用
|
EP3172235A2
(fr)
|
2014-07-25 |
2017-05-31 |
Cytomx Therapeutics Inc. |
Anticorps anti-cd3, anticorps anti-cd3 activables, anticorps anti-cd3 multispécifiques, anticorps anti-cd3 activables multispécifiques et procédés d'utilisation de ces anticorps
|
AU2015295242B2
(en)
|
2014-07-31 |
2020-10-22 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
EP3174901B1
(fr)
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Constructions optimisées d'anticorps monocaténaires, bispécifiques, spécifiques d'espèces croisées
|
EP3186237A1
(fr)
|
2014-08-28 |
2017-07-05 |
Medizinische Universität Wien |
Nouveaux dérivés de chalcone hétéro-aromatique et leur utilisation médicale
|
EP3875481A1
(fr)
|
2014-11-14 |
2021-09-08 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Anticorps neutralisants dirigés contre la glycoprotéine du virus d'ebola et leur utilisation
|
KR102614189B1
(ko)
|
2014-11-17 |
2023-12-18 |
리제너론 파아마슈티컬스, 인크. |
Cd3xcd20 이특이적 항체를 이용한 종양의 치료 방법
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
EP3223845B1
(fr)
|
2014-11-26 |
2021-05-19 |
Xencor, Inc. |
Anticorps hétérodimériques se liant à l'antigène cd3 et l'antigène cd20
|
MA41019A
(fr)
|
2014-11-26 |
2021-05-05 |
Xencor Inc |
Anticorps hétérodimériques se liant aux antigènes cd3 et cd38
|
EP3029067A1
(fr)
|
2014-12-01 |
2016-06-08 |
Deutsches Krebsforschungszentrum |
Utilisation de réactifs bloquants pour réduire l'activation de lymphocytes T non spécifiques
|
US20160168237A1
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
Method for treating a complement mediated disorder caused by an infectious agent in a patient
|
EP3237449A2
(fr)
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Anticorps trispécifiques
|
EP3247725B1
(fr)
|
2015-01-23 |
2020-07-01 |
Sanofi |
Anticorps anti-cd3, anticorps anti-cd123 et anticorps bispécifiques se liant spécifiquement au cd3 et/ou cd123
|
WO2016135140A1
(fr)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Dérivés de 4-aminoquinazoline en tant qu'inhibiteurs de mth1 pour la thérapie du cancer
|
WO2016135139A1
(fr)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Dérivés de 2,3-dihydrocyclopenta[b]quinoléine en tant qu'inhibiteurs de mth1 pour la thérapie du cancer
|
CA2976593A1
(fr)
|
2015-02-23 |
2016-09-01 |
Seagull Therapeutics Sas |
Semaphorines 3 non naturelles et leur utilisation medicale
|
WO2016135138A1
(fr)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Dérivés d'oxoquinoléine en tant qu'inhibiteurs de mth1 pour la thérapie du cancer
|
WO2016135137A1
(fr)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Dérivés de 4-(phénylamino)quinoléine substitués en tant qu'inhibiteurs de mth1 pour la thérapie du cancer
|
RU2733658C2
(ru)
|
2015-02-24 |
2020-10-06 |
Биоатла Ллс |
Условно активные биологические белки
|
KR20170140180A
(ko)
|
2015-02-24 |
2017-12-20 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
중동 호흡기 증후군 코로나 바이러스 면역원, 항체 및 그 용도
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
EP3064507A1
(fr)
|
2015-03-06 |
2016-09-07 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Protéines de fusion comprenant une protéine de liaison et un polypeptide interleukine-15 ayant une affinité réduite pour IL15ra et leurs utilisations thérapeutiques
|
US10562960B2
(en)
|
2015-03-20 |
2020-02-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to gp120 and their use
|
WO2016164558A1
(fr)
*
|
2015-04-07 |
2016-10-13 |
Children's Medical Center Corporation |
Procédés et compositions se rapportant à un modèle de tumeur à base de cellules souches embryonnaires
|
SG10201909308XA
(en)
|
2015-04-17 |
2019-11-28 |
Amgen Res Munich Gmbh |
Bispecific antibody constructs for cdh3 and cd3
|
EP3286224A4
(fr)
|
2015-04-22 |
2018-11-14 |
Immunomedics, Inc. |
Isolement, détection, diagnostic et/ou caractérisation de cellules cancéreuses trop-2 positives
|
EP3285753A1
(fr)
|
2015-04-22 |
2018-02-28 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Combinaison d'un anti-androgène avec un antagoniste de la vitamine k ou avec un inhibiteur de la gamma-glutamyl carboxylase pour la thérapie d'un cancer positif aux récepteurs des androgènes
|
EP3611192A3
(fr)
|
2015-05-13 |
2020-03-25 |
Ablynx N.V. |
Polypeptides de recrutement de lymphocytes t basés sur la réactivité tcr alpha/bêta
|
AU2016260909B2
(en)
|
2015-05-13 |
2019-08-22 |
Ablynx N.V. |
T cell recruiting polypeptides based on CD3 reactivity
|
MX2017015380A
(es)
|
2015-05-29 |
2018-03-28 |
Amphivena Therapeutics Inc |
Metodos para utilizar proteinas de enlace biespecificas cd3 y cd33.
|
WO2016196975A1
(fr)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Anticorps neutralisants dirigés contre la protéine d'enveloppe (env) du vih-1 et leur utilisation
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
CN106349391A
(zh)
*
|
2015-07-17 |
2017-01-25 |
中国科学院深圳先进技术研究院 |
Hbv特异性双靶向抗体及其制备方法和应用、含该双靶向抗体表达盒的微环dna及应用
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
PE20181275A1
(es)
|
2015-08-28 |
2018-08-03 |
Amunix Operating Inc |
Ensamble de polipeptido quimerico y metodos para hacer y usar el mismo
|
WO2017044811A1
(fr)
|
2015-09-11 |
2017-03-16 |
Bruce Andrien |
Variants d'éculizumab et d'éculizumab glycosylé de recombinaison
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
TWI836305B
(zh)
|
2015-09-24 |
2024-03-21 |
日商第一三共股份有限公司 |
抗garp抗體及其製造方法及用途
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
CN108026177B
(zh)
|
2015-10-02 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
双特异性抗cd19xcd3 t细胞活化性抗原结合分子
|
AU2016335750B2
(en)
|
2015-10-07 |
2023-05-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
US11203634B2
(en)
|
2015-10-07 |
2021-12-21 |
Alexion Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration in a patient comprising administering an anti-C5a antibody
|
JP7064769B2
(ja)
|
2015-11-02 |
2022-05-11 |
バイオアトラ、エルエルシー |
条件的活性型ポリペプチド
|
US11236152B2
(en)
|
2015-11-03 |
2022-02-01 |
The United States of America, as represented by the Sectetary, Department of Health and Human Services |
Neutralizing antibodies to HIV-1 GP41 and their use
|
CN105296421B
(zh)
*
|
2015-11-24 |
2019-01-29 |
高岱清 |
一种双特异性抗体活化的t细胞及制备方法与应用
|
RU2651776C2
(ru)
*
|
2015-12-01 |
2018-04-23 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Биспецифические антитела против cd3*cd19
|
CA3007030A1
(fr)
|
2015-12-07 |
2017-06-15 |
Xencor, Inc. |
Anticorps heterodimees se liant a cd3 et psma
|
HRP20211466T1
(hr)
|
2015-12-09 |
2021-12-24 |
Medizinische Universität Wien |
Spojevi platine funkcionalizirani monomaleimidom, namijenjeni terapiji raka
|
MY196756A
(en)
|
2015-12-14 |
2023-05-03 |
Macrogenics Inc |
Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
|
UA126656C2
(uk)
|
2016-02-03 |
2023-01-11 |
Емджен Рісерч (Мюнік) Гмбх |
Біспецифічна конструкція антитіла до psma і cd3, яке залучають t-клітини
|
MA43955B1
(fr)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Anticorps anti-bcma et anti-cd3 bispécifiques de format bite
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
CN108601841A
(zh)
|
2016-02-10 |
2018-09-28 |
免疫医疗公司 |
Abcg2抑制剂与sacituzumab govitecan(immu-132)的组合克服表达trop-2的癌中对sn-38的抗性
|
MX2018009870A
(es)
|
2016-02-15 |
2018-11-29 |
Cemm Forschungszentrum Fuer Molekulare Medizin Gmbh |
Inhibidores de taf1 para la terapia del cancer.
|
EP3216458A1
(fr)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Facteur de croissance endothéliale vasculaire (vegf-a)modifié et son utilisation médicale
|
KR20230148844A
(ko)
|
2016-03-29 |
2023-10-25 |
유니버시티 오브 써던 캘리포니아 |
암을 표적하는 키메라 항원 수용체
|
WO2017167350A1
(fr)
*
|
2016-03-30 |
2017-10-05 |
Horst Lindhofer |
Anticorps multispécifiques destinés à être utilisés pour le traitement d'un néoplasme du tractus urinaire
|
CA3020830A1
(fr)
*
|
2016-04-13 |
2017-10-19 |
Vivia Biotech, S.L |
Lymphocytes t actives ex vivo par bite.rtm.
|
WO2017181143A1
(fr)
|
2016-04-15 |
2017-10-19 |
Generon (Shanghai) Corporation, Ltd. |
Utilisation d'il-22 pour le traitement de l'entérocolite nécrosante
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
RU2725292C2
(ru)
|
2016-04-27 |
2020-06-30 |
Иммьюномедикс, Инк. |
Эффективность конъюгатов антитела против trop-2 с лекарственным средством sn-38 для терапии рецидивирующих/рефрактерных к ингибиторам контрольной точки опухолей
|
WO2017192589A1
(fr)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps neutralisants dirigés contre la grippe ha, leur utilisation et leur identification
|
CN105906720A
(zh)
*
|
2016-05-16 |
2016-08-31 |
武汉汉密顿生物科技股份有限公司 |
靶向性嵌合抗原受体修饰的免疫细胞及其制备方法和应用
|
RU2022104399A
(ru)
|
2016-06-14 |
2022-05-05 |
Ксенкор, Инк. |
Биспецифические антитела-ингибиторы контрольных точек
|
US10669338B2
(en)
|
2016-06-17 |
2020-06-02 |
Immunomedics, Inc. |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
|
CN116063545A
(zh)
|
2016-06-28 |
2023-05-05 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
BR112019000015A2
(pt)
|
2016-06-30 |
2019-04-24 |
Oncorus, Inc. |
distribuição por vírus oncolítico pseudotipado de polipeptídeos terapêuticos
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
IL305149A
(en)
|
2016-07-26 |
2023-10-01 |
Biomarin Pharm Inc |
Novel adeno-associated virus capsid proteins
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
TW201825511A
(zh)
|
2016-09-09 |
2018-07-16 |
美商艾斯合顧問有限公司 |
表現免疫檢查點調節子的溶瘤病毒
|
WO2018057915A1
(fr)
|
2016-09-23 |
2018-03-29 |
The Regents Of The University Of Michigan |
Lymphocytes modifiés
|
KR102649972B1
(ko)
|
2016-10-14 |
2024-03-22 |
젠코어 인코포레이티드 |
IL15/IL15Rα 이종이량체 Fc-융합 단백질
|
ES2848206T3
(es)
|
2016-10-19 |
2021-08-05 |
Alexion Pharma Inc |
Un método de cuantificar C5 sin unir en una muestra
|
JP2020511401A
(ja)
|
2016-11-14 |
2020-04-16 |
チェム−フォルシュングスツェントルン フュル モレクラーレ メディツィン ゲゼルシャフト ミット ベシュレンクテル ハフツング |
癌の治療法のためのbrd4阻害剤と葉酸代謝拮抗薬との組み合わせ物
|
WO2018091606A1
(fr)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
Polypeptides de recrutement de lymphocytes t capables de se lier à cd123 et tcr alpha/bêta
|
US11427633B2
(en)
*
|
2016-12-13 |
2022-08-30 |
Crage Medical Co., Limited |
Anti-CD19 humanized antibody and immune effector cell targeting cd 19
|
CN108264557B
(zh)
*
|
2016-12-30 |
2021-08-24 |
惠和生物技术(上海)有限公司 |
一种结合cd3和t细胞负共刺激分子的双功能分子及其应用
|
CN108264566B
(zh)
*
|
2016-12-30 |
2021-05-14 |
惠和生物技术(上海)有限公司 |
一种融合抗cd3抗体结构域和t细胞正共刺激分子配体的双特异性分子及其应用
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
KR20190118172A
(ko)
|
2017-02-08 |
2019-10-17 |
드래곤플라이 쎄라퓨틱스, 인크. |
천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도
|
WO2018148660A1
(fr)
|
2017-02-10 |
2018-08-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps neutralisants dirigés contre la protéine circumsporozoïte de plasmodium falciparum et leur utilisation
|
WO2018152496A1
(fr)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions et méthodes de diagnostic et de traitement de l'infection par le virus zika
|
KR20190120782A
(ko)
|
2017-02-20 |
2019-10-24 |
드래곤플라이 쎄라퓨틱스, 인크. |
Her2, nkg2d 및 cd16에 결합하는 단백질
|
US11459394B2
(en)
|
2017-02-24 |
2022-10-04 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
JP2020512314A
(ja)
|
2017-03-27 |
2020-04-23 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
サシツズマブゴビテカンとRAD51阻害剤を用いたTrop−2発現トリプルネガティブ乳癌の治療
|
CN108659112B
(zh)
*
|
2017-03-30 |
2021-01-26 |
上海市同济医院 |
一种非对称双特异性抗体
|
EP3606964A4
(fr)
|
2017-04-03 |
2020-12-09 |
Immunomedics, Inc. |
Administration par voie sous-cutanée de conjugués anticorps-médicament à titre de thérapie anticancéreuse
|
EP3615569A1
(fr)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Anticorps et procédés de diagnostic et de traitement d'infection par le virus d'epstein barr
|
KR102663596B1
(ko)
|
2017-04-26 |
2024-05-10 |
유레카 쎄라퓨틱스, 인코포레이티드 |
글리피칸 3을 특이적으로 인식하는 구축물 및 그의 용도
|
AU2018261951A1
(en)
|
2017-05-05 |
2019-10-31 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
WO2018224441A1
(fr)
|
2017-06-05 |
2018-12-13 |
Numab Innovation Ag |
Nouveaux anticorps anti-cd3
|
EP3645048A4
(fr)
*
|
2017-06-25 |
2021-06-16 |
Systimmune, Inc. |
Anticorps multispécifiques et procédés de fabrication et d'utilisation associés
|
CA3067603A1
(fr)
|
2017-06-30 |
2019-01-03 |
Xencor, Inc. |
Proteines de fusion fc heterodimeres ciblees contenant il-15/il-15ra et domaines de liaison a l'antigene
|
EP3655430A1
(fr)
|
2017-07-19 |
2020-05-27 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Anticorps et procédés de diagnostic et de traitement d'infection par le virus de l'hépatite b
|
CR20200099A
(es)
|
2017-08-03 |
2020-07-24 |
Amgen Inc |
Muteínas de interleucina 21 y métodos de tratamiento
|
EP3679067A2
(fr)
|
2017-09-08 |
2020-07-15 |
Maverick Therapeutics, Inc. |
Protéines de liaison à activation conditionnelle restreinte
|
SG11202001499WA
(en)
|
2017-09-08 |
2020-03-30 |
Amgen Inc |
Inhibitors of kras g12c and methods of using the same
|
MA50239A
(fr)
|
2017-09-15 |
2020-07-22 |
Amgen Inc |
Procédé de formulation pharmaceutique lyophilisée d'une protéine thérapeutique
|
US11912754B2
(en)
|
2017-10-12 |
2024-02-27 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
BR112020007203A2
(pt)
|
2017-10-13 |
2020-10-20 |
Merck Sharp & Dohme Corp. |
composições e métodos para tratamento de linfoma difuso de células b grandes
|
CA3078911A1
(fr)
|
2017-10-14 |
2019-04-18 |
Cytomx Therapeutics, Inc. |
Anticorps, anticorps activables, anticorps bispecifiques, et anticorps activables bispecifiques et leurs procedes d'utilisation
|
CN107739410B
(zh)
*
|
2017-10-18 |
2021-07-30 |
南京鼓楼医院 |
CD3单链抗体-iRGD融合蛋白、制备及其作为抗肿瘤药物的应用
|
AU2018358804A1
(en)
|
2017-11-02 |
2020-04-09 |
Bayer Aktiengesellschaft |
Bispecific antibodies binding ALK-1 and BMPR-2
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
AU2018366199A1
(en)
|
2017-11-08 |
2020-05-28 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
JP7344206B2
(ja)
|
2017-12-11 |
2023-09-13 |
アムジェン インコーポレイテッド |
二重特異性抗体製品のための連続製造プロセス
|
EP3724231A4
(fr)
|
2017-12-12 |
2021-08-11 |
MacroGenics, Inc. |
Dérivés de molécules de liaison à cd-16 bispécifiques et leur utilisation dans le traitement de maladies
|
CA3086199A1
(fr)
|
2017-12-19 |
2019-06-27 |
Xencor, Inc. |
Proteines de fusion il-2 fc modifiees
|
JP2021508477A
(ja)
|
2017-12-29 |
2021-03-11 |
オンコラス, インコーポレイテッド |
治療用ポリペプチドの腫瘍溶解性ウイルス送達
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
US11976109B2
(en)
|
2018-01-02 |
2024-05-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
CN107987169B
(zh)
*
|
2018-01-05 |
2021-10-08 |
阿思科力(苏州)生物科技有限公司 |
一种以ROBO1为靶点的双特异性抗体scFv及其制备和应用
|
UY38049A
(es)
|
2018-01-12 |
2019-07-31 |
Amgen Inc |
Anti-pd-1 anticuerpos y métodos de tratamiento
|
MX2020008336A
(es)
|
2018-02-08 |
2020-09-21 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d.
|
KR20200121834A
(ko)
|
2018-02-15 |
2020-10-26 |
마크로제닉스, 인크. |
변이체 cd3-결합 도메인 및 질환 치료를 위한 병용 요법에서의 그것의 용도
|
EP3755713A1
(fr)
|
2018-02-21 |
2020-12-30 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Anticorps neutralisants dirigés contre la protéine d'enveloppe (env) du vih-1 et leur utilisation
|
CA3089230A1
(fr)
|
2018-03-02 |
2019-09-06 |
Cdr-Life Ag |
Proteines de liaison a un antigene trispecifiques
|
WO2019177011A1
(fr)
*
|
2018-03-13 |
2019-09-19 |
国立大学法人大阪大学 |
Immunostimulateur de tumeur
|
US20190284288A1
(en)
|
2018-03-19 |
2019-09-19 |
The Regents Of The University Of Michigan |
Compositions and methods for t-cell and cytokine activation
|
US10982006B2
(en)
|
2018-04-04 |
2021-04-20 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
EP3781599A1
(fr)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Protéines de fusion hétérodimères ciblant pd-1 contenant des protéines de fusion fc d'il-15/il-15ra, domaines de liaison à l'antigène pd-1 et utilisations associées
|
CA3097741A1
(fr)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Proteines de fusion heterodimeres ciblant tim-3 contenant des proteines de fusion fc d'il-15/il-15ra et domaines de liaison a l'antigene de tim-3
|
WO2019207051A1
(fr)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Utilisation médicale de combinaisons de sémaphorines 3 et d'antimétabolites non naturels
|
US20210171610A1
(en)
|
2018-05-02 |
2021-06-10 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
CN113164762A
(zh)
|
2018-05-09 |
2021-07-23 |
生物马林药物股份有限公司 |
苯丙酮尿症的治疗方法
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
WO2019241315A1
(fr)
|
2018-06-12 |
2019-12-19 |
Obsidian Therapeutics, Inc. |
Constructions régulatrices dérivées de pde5 et procédés d'utilisation en immunothérapie
|
WO2020010079A2
(fr)
|
2018-07-02 |
2020-01-09 |
Amgen Inc. |
Protéine de liaison à l'antigène anti-steap1
|
TW202021616A
(zh)
|
2018-07-30 |
2020-06-16 |
美商安進公司 |
結合至cd33和cd3的雙特異性抗體構建體之延長投與
|
WO2020025596A1
(fr)
|
2018-07-31 |
2020-02-06 |
Amgen Research (Munich) Gmbh |
Régime posologique pour anticorps bispécifiques bcma-cd3
|
EP3829633A1
(fr)
|
2018-08-03 |
2021-06-09 |
Amgen Research (Munich) GmbH |
Constructions d'anticorps pour cldn18.2 et cd3
|
MX2021002190A
(es)
|
2018-08-31 |
2021-05-14 |
Regeneron Pharma |
Estrategia de dosificacion que mitiga el sindrome de liberacion de citoquinas para los anticuerpos biespecificos cd3/cd20.
|
US11066476B2
(en)
|
2018-09-14 |
2021-07-20 |
Shanghai tongji hospital |
Asymmetric bispecific antibody
|
CN110590955B
(zh)
*
|
2018-09-17 |
2021-05-18 |
北京盛诺基医药科技股份有限公司 |
一种双特异性抗体
|
WO2020068623A1
(fr)
|
2018-09-24 |
2020-04-02 |
Amgen Inc. |
Systèmes et procédés de dosage interventionnel
|
CN112703204A
(zh)
|
2018-09-28 |
2021-04-23 |
安进公司 |
针对可溶性bcma的抗体
|
WO2020072821A2
(fr)
|
2018-10-03 |
2020-04-09 |
Xencor, Inc. |
Protéines de fusion fc hétérodimères d'il -12
|
MX2021003976A
(es)
|
2018-10-11 |
2021-05-27 |
Amgen Inc |
Procesamiento posterior de constructos de anticuerpos biespecificos.
|
WO2020086635A1
(fr)
|
2018-10-23 |
2020-04-30 |
Amgen Inc. |
Étalonnage automatique et maintenance automatique de modèles de spectroscopie raman pour des prédictions en temps réel
|
EP3883610A4
(fr)
|
2018-11-20 |
2022-11-02 |
Cornell University |
Complexes macrocycliques de radionucléides et leur utilisation en radiothérapie du cancer
|
WO2020132214A2
(fr)
|
2018-12-20 |
2020-06-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux spécifiques de la glycoprotéine du virus ebola et utilisations associées
|
TW202043253A
(zh)
|
2019-01-28 |
2020-12-01 |
美商安進公司 |
藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程
|
JP2022521200A
(ja)
|
2019-02-20 |
2022-04-06 |
アムジエン・インコーポレーテツド |
タンパク質の安定性を決定する方法
|
MX2021010390A
(es)
|
2019-03-01 |
2021-11-17 |
Xencor Inc |
Anticuerpos heterodimericos que se unen a enpp3 y cd3.
|
CN114390938A
(zh)
|
2019-03-05 |
2022-04-22 |
武田药品工业有限公司 |
受约束的条件性活化的结合蛋白
|
JP2022527062A
(ja)
|
2019-03-27 |
2022-05-30 |
アムジェン インコーポレイテッド |
製剤化された生物製剤製品のための、天然存在比での二次元(2d)核磁気共鳴技術によって治療用タンパク質をフィンガープリントする方法
|
WO2020221792A1
(fr)
|
2019-04-30 |
2020-11-05 |
Amgen Research (Munich) Gmbh |
Moyens et méthodes de traitement du lymphome ou de la leucémie de burkitt
|
EP3962523A2
(fr)
|
2019-05-03 |
2022-03-09 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Anticorps neutralisants dirigés contre la protéine circumsporozoïte de plasmodium falciparum et leur utilisation
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
US20220227888A1
(en)
|
2019-06-07 |
2022-07-21 |
Amgen Inc. |
Bispecific binding constructs with selectively cleavable linkers
|
EP3983520A1
(fr)
|
2019-06-13 |
2022-04-20 |
Amgen, Inc |
Commande de perfusion contenant de la biomasse automatisée dans la fabrication de produits biologiques
|
CN114269783B
(zh)
|
2019-07-02 |
2024-03-26 |
美国政府(由卫生和人类服务部的部长所代表) |
结合egfrviii的单克隆抗体及其应用
|
CN110623921B
(zh)
*
|
2019-08-15 |
2020-10-30 |
北京东方百泰生物科技股份有限公司 |
一种抗cd3和抗cd19的双特异性抗体注射制剂
|
RU2738802C1
(ru)
*
|
2019-08-21 |
2020-12-17 |
Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" |
Определяющие комплементарность участки для связывания cd3 и содержащая их биспецифическая антигенсвязывающая молекула
|
GB201912681D0
(en)
|
2019-09-04 |
2019-10-16 |
Eth Zuerich |
Bispecific binding agent that binds to cd117/c-kit and cd3
|
MX2022002981A
(es)
|
2019-09-10 |
2022-04-06 |
Amgen Inc |
Metodo de purificacion para polipeptidos de union a antigeno biespecificos con capacidad de union dinamica de captura de proteina l mejorada.
|
CA3151704A1
(fr)
|
2019-10-02 |
2021-04-08 |
Domain Therapeutics |
Antagonistes du recepteur ep4 de la prostaglandine e2 (pge2)
|
WO2021074414A1
(fr)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Composés d'ubiquitine ligase cullin ring du type thioazole et oxazole et leurs utilisations
|
EP3808741A1
(fr)
|
2019-10-16 |
2021-04-21 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Composés pour la dégradation ciblée de protéines porteuses et leurs utilisations
|
WO2021074418A1
(fr)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Composés d'ubiquitine ligase cullin ring du type carbazole et leurs utilisations
|
TW202132340A
(zh)
|
2019-11-04 |
2021-09-01 |
美商安進公司 |
治療白血病之方法
|
EP3819312A1
(fr)
|
2019-11-10 |
2021-05-12 |
Amgen, Inc |
Régime de dosage pour agents anti-dll3
|
EP3819007A1
(fr)
|
2019-11-11 |
2021-05-12 |
Amgen Research (Munich) GmbH |
Régime de dosage pour agents anti-bcma
|
EP4058485A1
(fr)
|
2019-11-13 |
2022-09-21 |
Amgen Inc. |
Procédé de réduction de la formation d'agrégats dans le traitement en aval de molécules de liaison à l'antigène bispécifiques
|
EP4093771A1
(fr)
|
2020-01-22 |
2022-11-30 |
Amgen Research (Munich) GmbH |
Combinaisons de constructions d'anticorps et d'inhibiteurs du syndrome de libération de cytokine et leurs utilisations
|
KR20220144377A
(ko)
|
2020-01-30 |
2022-10-26 |
우모자 바이오파마 인코포레이티드 |
이중특이적 형질도입 촉진제
|
WO2021158469A1
(fr)
|
2020-02-03 |
2021-08-12 |
Amgen Inc. |
Approche d'encadrement à plusieurs variables pour la validation d'un filtre stérile
|
TW202140561A
(zh)
|
2020-02-14 |
2021-11-01 |
日商協和麒麟股份有限公司 |
與cd3結合之雙特異性抗體
|
KR20220148209A
(ko)
|
2020-02-28 |
2022-11-04 |
상하이 헨리우스 바이오테크, 인크. |
항cd137 작제물 및 그 용도
|
JP2023516941A
(ja)
|
2020-02-28 |
2023-04-21 |
上海復宏漢霖生物技術股▲フン▼有限公司 |
抗cd137コンストラクト、多重特異性抗体及びその使用
|
IL296241A
(en)
|
2020-03-10 |
2022-11-01 |
Massachusetts Inst Technology |
Compositions and methods for immunotherapy for npm1c-positive cancer
|
TW202200615A
(zh)
|
2020-03-12 |
2022-01-01 |
美商安進公司 |
用於治療和預防患者的crs之方法
|
CA3175275A1
(fr)
|
2020-03-19 |
2021-09-23 |
Amgen Inc. |
Anticorps contre la mucine 17 et leurs utilisations
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
JP2023527293A
(ja)
|
2020-05-19 |
2023-06-28 |
アムジエン・インコーポレーテツド |
Mageb2結合構築物
|
AU2021281554A1
(en)
|
2020-05-29 |
2022-12-15 |
Amgen Inc. |
Adverse effects-mitigating administration of a bispecific antibody construct binding to CD33 and CD3
|
MX2022015376A
(es)
|
2020-06-02 |
2023-04-14 |
Dynamicure Biotechnology Llc |
Construcciones anti grupo de diferenciacion 93 (cd93) y usos de las mismas.
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
AU2021283933A1
(en)
|
2020-06-04 |
2023-01-05 |
Amgen Inc. |
Bispecific binding constructs
|
WO2022026763A1
(fr)
|
2020-07-29 |
2022-02-03 |
Dynamicure Biotechnology Llc |
Constructions anti-cd93 et leurs utilisations
|
AU2021329378A1
(en)
|
2020-08-19 |
2023-03-23 |
Xencor, Inc. |
Anti-CD28 compositions
|
IL300764A
(en)
|
2020-08-27 |
2023-04-01 |
Juntendo Educational Found |
Antibody and composition of calr-cd3 mutant anti-clotting drugs
|
CA3194762A1
(fr)
|
2020-09-11 |
2022-03-17 |
Amgen Inc. |
Materiaux et procedes permettant de reduire l'agregation de proteines
|
MX2023003041A
(es)
|
2020-09-16 |
2023-05-09 |
Amgen Inc |
Métodos para administrar dosis terapéuticas de moléculas de acoplamiento a células t biespecíficas para el tratamiento de cáncer.
|
WO2022060878A1
(fr)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Méthodes de traitement du cancer de la prostate
|
WO2022079290A2
(fr)
|
2020-10-16 |
2022-04-21 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Composés d'ubiquitine ligase cullin ring et utilisations associées
|
JP2023547661A
(ja)
|
2020-11-06 |
2023-11-13 |
アムジエン・インコーポレーテツド |
Cd3に結合するポリペプチド構築物
|
CR20230235A
(es)
|
2020-11-06 |
2023-10-05 |
Amgen Res Munich Gmbh |
Construcciones polipeptídicas que se unen selectivamente a cldn6 y cd3
|
AU2021374839A1
(en)
|
2020-11-06 |
2023-06-08 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
WO2022096704A1
(fr)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Domaine de liaison à l'antigène à taux de coupure réduit
|
WO2022103781A1
(fr)
|
2020-11-10 |
2022-05-19 |
Amgen Inc. |
Procédés d'administration d'une molécule de liaison à bcma x cd3
|
CN116783217A
(zh)
|
2020-12-03 |
2023-09-19 |
安进公司 |
具有多个结合结构域的免疫球蛋白构建体
|
WO2022132904A1
(fr)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux humains ciblant le sars-cov-2
|
IL303740A
(en)
|
2020-12-18 |
2023-08-01 |
Sanofi Sa |
Polypeptides that recruit T cells based on reactivity to alpha/beta receptors
|
CN116917326A
(zh)
|
2021-01-22 |
2023-10-20 |
博泰康医药公司 |
抗her-2/trop-2构建体及其用途
|
EP4284512A1
(fr)
|
2021-01-28 |
2023-12-06 |
Regeneron Pharmaceuticals, Inc. |
Compositions et méthodes de traitement du syndrome de libération de cytokines
|
EP4291226A1
(fr)
|
2021-02-09 |
2023-12-20 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Anticorps ciblant la protéine de spicule de coronavirus
|
WO2022171121A1
(fr)
|
2021-02-10 |
2022-08-18 |
同润生物医药(上海)有限公司 |
Méthode et combinaison pour le traitement de tumeurs
|
AU2022220611A1
(en)
|
2021-02-09 |
2023-08-24 |
University Of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
AU2022232375A1
(en)
|
2021-03-09 |
2023-09-21 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
US11859012B2
(en)
|
2021-03-10 |
2024-01-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and GPC3
|
US20240051990A1
(en)
|
2021-03-10 |
2024-02-15 |
Amgen Inc. |
Methods for purification of recombinant proteins
|
US20240075406A1
(en)
|
2021-03-10 |
2024-03-07 |
Amgen Inc. |
Parallel chromatography systems and methods
|
CN117616041A
(zh)
|
2021-03-25 |
2024-02-27 |
当康生物技术有限责任公司 |
抗-igfbp7构建体及其用途
|
CN112794916B
(zh)
*
|
2021-04-08 |
2021-08-10 |
正大天晴药业集团南京顺欣制药有限公司 |
三特异性抗原结合构建体及构建方法和应用
|
AU2022269312A1
(en)
|
2021-05-06 |
2023-10-19 |
Amgen Research (Munich) Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
WO2022266660A1
(fr)
|
2021-06-17 |
2022-12-22 |
Amberstone Biosciences, Inc. |
Constructions anti-cd3 et utilisations associées
|
AU2022345251A1
(en)
|
2021-09-17 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Synthetic humanized llama nanobody library and use thereof to identify sars-cov-2 neutralizing antibodies
|
TW202332695A
(zh)
|
2021-10-15 |
2023-08-16 |
德商安美基研究(慕尼黑)公司 |
結合cd19的t細胞接合劑之皮下投與
|
CA3236194A1
(fr)
|
2021-10-27 |
2023-05-04 |
Amgen Inc. |
Prediction fondee sur un apprentissage profond pour la surveillance de produits pharmaceutiques par spectroscopie
|
EP4180035A1
(fr)
|
2021-11-15 |
2023-05-17 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Nouveaux inhibiteurs bêta-lactone des enzymes hydrolytiques et leurs utilisations médicale et non médicale
|
CA3240046A1
(fr)
|
2021-12-14 |
2023-06-22 |
Cdr-Life Ag |
Activateur double de lymphocytes t ciblant le cmh
|
WO2023154824A1
(fr)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux humains ciblant largement les coronavirus
|
WO2023164474A1
(fr)
|
2022-02-23 |
2023-08-31 |
Amgen Inc. |
Traitement du cancer ciblant dll3
|
WO2023192881A1
(fr)
|
2022-03-28 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps neutralisants dirigés contre la protéine d'enveloppe (env) du vih-1 et leur utilisation
|
WO2023201226A1
(fr)
|
2022-04-11 |
2023-10-19 |
Regeneron Pharmaceuticals, Inc. |
Compositions et méthodes permettant la destruction de cellule tumorale universelle
|
WO2023203174A1
(fr)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Composés d'ubiquitine ligase cullin ring hétérocycliques et leurs utilisations
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
具有增加的選擇性的多鏈多靶向性雙特異性抗原結合分子
|
US20240117062A1
(en)
|
2022-05-27 |
2024-04-11 |
Sanofi |
Anti-bcma antibodies
|
US20240109965A1
(en)
|
2022-06-14 |
2024-04-04 |
Ablynx N.V. |
Immunoglobulin single variable domains targeting t cell receptor
|
WO2024030829A1
(fr)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps monoclonaux se liant à la face inférieure de la neuraminidase virale de la grippe
|
WO2024054822A1
(fr)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps du sars-cov -2 modifiés ayant une largeur de neutralisation accrue
|
US20240091262A1
(en)
|
2022-09-14 |
2024-03-21 |
Cdr-Life Ag |
Mage-a4 peptide dual t cell engagers
|
WO2024059675A2
(fr)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Composition de stabilisation de molécule bispécifique
|
WO2024064826A1
(fr)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticorps neutralisants dirigés contre la protéine plasmodium falciparum circumsporozoïte et leur utilisation
|
WO2024068944A1
(fr)
|
2022-09-30 |
2024-04-04 |
Sanofi |
Anticorps anti-cd28
|
WO2024077044A1
(fr)
|
2022-10-05 |
2024-04-11 |
Amgen Inc. |
Polythérapies comprenant des thérapies de redirection de lymphocytes t et des anticorps agonistes anti-il-2r ou des fragments de ceux-ci
|
WO2024092033A1
(fr)
|
2022-10-26 |
2024-05-02 |
Amgen Inc. |
Molécules multispécifiques pour la clairance d'immunoglobulines dans le traitement de maladies induites par des auto-anticorps
|