SG11201700416TA - Treatment of cancer using a cd33 chimeric antigen receptor - Google Patents

Treatment of cancer using a cd33 chimeric antigen receptor

Info

Publication number
SG11201700416TA
SG11201700416TA SG11201700416TA SG11201700416TA SG11201700416TA SG 11201700416T A SG11201700416T A SG 11201700416TA SG 11201700416T A SG11201700416T A SG 11201700416TA SG 11201700416T A SG11201700416T A SG 11201700416TA SG 11201700416T A SG11201700416T A SG 11201700416TA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
antigen receptor
chimeric antigen
chimeric
Prior art date
Application number
SG11201700416TA
Other languages
English (en)
Inventor
Jennifer Brogdon
Hilmar Ebersbach
Saar Gill
David Glass
Thomas Huber
Julia Jascur
Saad Kenderian
Joan Mannick
Michael C Milone
Leon Murphy
Celeste Richardson
Reshma Singh
Huijuan Song
Qilong Wu
Jiquan Zhang
Original Assignee
Novartis Ag
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Univ Pennsylvania filed Critical Novartis Ag
Publication of SG11201700416TA publication Critical patent/SG11201700416TA/en

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    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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SG11201700416TA 2014-07-21 2015-07-21 Treatment of cancer using a cd33 chimeric antigen receptor SG11201700416TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2014082589 2014-07-21
CN2014090504 2014-11-06
PCT/US2015/041390 WO2016014576A1 (en) 2014-07-21 2015-07-21 Treatment of cancer using a cd33 chimeric antigen receptor

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JP (2) JP6831777B2 (enExample)
KR (1) KR102594343B1 (enExample)
CN (2) CN107109419B (enExample)
AU (2) AU2015292755B2 (enExample)
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IL (1) IL250138B (enExample)
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TW (1) TWI719942B (enExample)
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Families Citing this family (203)

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Publication number Priority date Publication date Assignee Title
SG11201404284SA (en) 2012-02-22 2014-10-30 Univ Pennsylvania Use of the cd2 signaling domain in second-generation chimeric antigen receptors
US20150320799A1 (en) 2012-12-20 2015-11-12 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
WO2014130635A1 (en) 2013-02-20 2014-08-28 Novartis Ag Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
EP2958943B1 (en) 2013-02-20 2019-09-11 The Trustees Of The University Of Pennsylvania Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
US9745368B2 (en) 2013-03-15 2017-08-29 The Trustees Of The University Of Pennsylvania Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
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