ES2805475T3 - Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 - Google Patents

Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 Download PDF

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Publication number
ES2805475T3
ES2805475T3 ES15745069T ES15745069T ES2805475T3 ES 2805475 T3 ES2805475 T3 ES 2805475T3 ES 15745069 T ES15745069 T ES 15745069T ES 15745069 T ES15745069 T ES 15745069T ES 2805475 T3 ES2805475 T3 ES 2805475T3
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Spain
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seq
amino acid
cdr1
cdr2
cdr3
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ES15745069T
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English (en)
Spanish (es)
Inventor
Saad Kenderian
Jennifer Brogdon
Hilmar Ebersbach
Saar Gill
David Glass
Thomas Huber
Julia Jascur
Joan Mannick
Michael C Milone
Leon Murphy
Celeste Richardson
Reshma Singh
Huijuan Song
Qilong Wu
Jiquan Zhang
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Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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ES15745069T 2014-07-21 2015-07-21 Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 Active ES2805475T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2014082589 2014-07-21
CN2014090504 2014-11-06
PCT/US2015/041390 WO2016014576A1 (en) 2014-07-21 2015-07-21 Treatment of cancer using a cd33 chimeric antigen receptor

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ES2805475T3 true ES2805475T3 (es) 2021-02-12

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ES15745069T Active ES2805475T3 (es) 2014-07-21 2015-07-21 Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33

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US (4) US9777061B2 (enExample)
EP (2) EP3722316A1 (enExample)
JP (2) JP6831777B2 (enExample)
KR (1) KR102594343B1 (enExample)
CN (2) CN107109419B (enExample)
AU (2) AU2015292755B2 (enExample)
BR (1) BR112017001242A2 (enExample)
CA (1) CA2955154C (enExample)
CO (1) CO2017000510A2 (enExample)
ES (1) ES2805475T3 (enExample)
IL (1) IL250138B (enExample)
MX (1) MX390943B (enExample)
RU (1) RU2747384C2 (enExample)
SG (2) SG10201913765YA (enExample)
TW (1) TWI719942B (enExample)
WO (1) WO2016014576A1 (enExample)
ZA (1) ZA201700157B (enExample)

Families Citing this family (201)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014DN06522A (enExample) * 2012-02-22 2015-06-12 Univ Pennsylvania
ES2776698T3 (es) 2012-12-20 2020-07-31 Purdue Research Foundation Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
UY35340A (es) 2013-02-20 2014-09-30 Novartis Ag Marcaje efectivo de leucemia humana usando células diseñadas con un receptor quimérico de antígeno anti-cd123
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