ES2805475T3 - Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 - Google Patents

Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 Download PDF

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Publication number
ES2805475T3
ES2805475T3 ES15745069T ES15745069T ES2805475T3 ES 2805475 T3 ES2805475 T3 ES 2805475T3 ES 15745069 T ES15745069 T ES 15745069T ES 15745069 T ES15745069 T ES 15745069T ES 2805475 T3 ES2805475 T3 ES 2805475T3
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Spain
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seq
amino acid
cdr1
cdr2
cdr3
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English (en)
Spanish (es)
Inventor
Saad Kenderian
Jennifer Brogdon
Hilmar Ebersbach
Saar Gill
David Glass
Thomas Huber
Julia Jascur
Joan Mannick
Michael C Milone
Leon Murphy
Celeste Richardson
Reshma Singh
Huijuan Song
Qilong Wu
Jiquan Zhang
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Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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ES15745069T 2014-07-21 2015-07-21 Tratamiento del cáncer utilizando un receptor antigénico quimérico de CD33 Active ES2805475T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2014082589 2014-07-21
CN2014090504 2014-11-06
PCT/US2015/041390 WO2016014576A1 (en) 2014-07-21 2015-07-21 Treatment of cancer using a cd33 chimeric antigen receptor

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ES2805475T3 true ES2805475T3 (es) 2021-02-12

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EP (2) EP3722316A1 (enExample)
JP (2) JP6831777B2 (enExample)
KR (1) KR102594343B1 (enExample)
CN (2) CN112481283A (enExample)
AU (2) AU2015292755B2 (enExample)
BR (1) BR112017001242A2 (enExample)
CA (1) CA2955154C (enExample)
CO (1) CO2017000510A2 (enExample)
ES (1) ES2805475T3 (enExample)
IL (1) IL250138B (enExample)
MX (1) MX390943B (enExample)
RU (1) RU2747384C2 (enExample)
SG (2) SG10201913765YA (enExample)
TW (1) TWI719942B (enExample)
WO (1) WO2016014576A1 (enExample)
ZA (1) ZA201700157B (enExample)

Families Citing this family (207)

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Publication number Priority date Publication date Assignee Title
AU2013222284A1 (en) 2012-02-22 2014-08-07 The Trustees Of The University Of Pennsylvania Use of the CD2 signaling domain in second-generation chimeric antigen receptors
EP3653212B1 (en) 2012-12-20 2023-04-26 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
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