|
IL112372A
(en)
*
|
1994-02-07 |
2001-08-26 |
Res Dev Foundation |
Non-viral vector for the delivery of genetic information to cells
|
|
US7429646B1
(en)
|
1995-06-05 |
2008-09-30 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor-like 2
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
|
US6635743B1
(en)
|
1996-03-22 |
2003-10-21 |
Human Genome Sciences, Inc. |
Apoptosis inducing molecule II and methods of use
|
|
US7964190B2
(en)
|
1996-03-22 |
2011-06-21 |
Human Genome Sciences, Inc. |
Methods and compositions for decreasing T-cell activity
|
|
US6812327B1
(en)
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
|
US8212004B2
(en)
|
1999-03-02 |
2012-07-03 |
Human Genome Sciences, Inc. |
Neutrokine-alpha fusion proteins
|
|
ZA9811162B
(en)
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
|
US6417168B1
(en)
|
1998-03-04 |
2002-07-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
|
AU3072799A
(en)
|
1998-03-19 |
1999-10-11 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
|
AU3501700A
(en)
|
1999-02-26 |
2000-09-14 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
|
DE10084743T1
(de)
|
1999-06-25 |
2002-08-14 |
Genentech Inc |
Humanisierte Anti-ErbB2-Antikörper und Behandlung mit Anti-ErbB2-Antikörpern
|
|
TR200200472T2
(tr)
|
1999-08-27 |
2002-06-21 |
Genentech, Inc. |
Anti-Erb B2 antikorları ile tedavi için dozajlar
|
|
AU2002219944B2
(en)
|
2000-11-28 |
2008-02-21 |
Medimmune, Llc |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
KR20020093029A
(ko)
|
2000-04-11 |
2002-12-12 |
제넨테크, 인크. |
다가 항체 및 그의 용도
|
|
PL217410B1
(pl)
|
2000-05-19 |
2014-07-31 |
Genentech Inc |
Zastosowanie antagonisty ErbB, antagonista ErbB do zastosowania w metodzie leczenia raka i sposób identyfikacji pacjenta skłonnego do korzystnej odpowiedzi na antagonistę ErbB przy leczeniu raka
|
|
US20030031675A1
(en)
|
2000-06-06 |
2003-02-13 |
Mikesell Glen E. |
B7-related nucleic acids and polypeptides useful for immunomodulation
|
|
WO2001096528A2
(en)
|
2000-06-15 |
2001-12-20 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
|
WO2002002641A1
(en)
|
2000-06-16 |
2002-01-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
EP1299128A2
(en)
|
2000-06-20 |
2003-04-09 |
Idec Pharmaceuticals Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
WO2002016412A2
(en)
|
2000-08-18 |
2002-02-28 |
Dyax Corp. |
Binding polypeptides for b lymphocyte stimulator protein (blys)
|
|
US20030091565A1
(en)
|
2000-08-18 |
2003-05-15 |
Beltzer James P. |
Binding polypeptides and methods based thereon
|
|
EP1355919B1
(en)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules with extended half-lives, compositions and uses thereof
|
|
EP1683865A3
(en)
|
2001-02-02 |
2006-10-25 |
Eli Lilly & Company |
Mammalian proteins and in particular CD200
|
|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
|
JP2004536579A
(ja)
|
2001-04-13 |
2004-12-09 |
ヒューマン ジノーム サイエンシーズ， インコーポレイテッド |
血管内皮増殖因子２
|
|
KR101021124B1
(ko)
*
|
2001-05-24 |
2011-03-14 |
지모제넥틱스, 인코포레이티드 |
Ｔａｃｉ-면역글로불린 융합 단백질
|
|
MXPA03010747A
(es)
|
2001-05-25 |
2004-03-02 |
Human Genome Sciences Inc |
Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
|
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
|
US7803915B2
(en)
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
|
CA2633413C
(en)
|
2001-06-20 |
2012-08-21 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
|
US6867189B2
(en)
|
2001-07-26 |
2005-03-15 |
Genset S.A. |
Use of adipsin/complement factor D in the treatment of metabolic related disorders
|
|
ATE516042T1
(de)
|
2001-09-18 |
2011-07-15 |
Genentech Inc |
Zusammensetzungen und verfahren zur behandlung und diagnose von tumoren
|
|
EP2067472A1
(en)
|
2002-01-02 |
2009-06-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
NZ535425A
(en)
|
2002-03-13 |
2008-05-30 |
Biogen Idec Inc |
Anti-alphavbeta6 antibodies
|
|
EP1499352A4
(en)
|
2002-04-12 |
2006-10-11 |
Medimmune Inc |
ANTI-INTERLEUKIN-9 RECOMBINANT ANTIBODIES
|
|
AU2003230874A1
(en)
|
2002-04-16 |
2003-11-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CN100418981C
(zh)
|
2002-06-10 |
2008-09-17 |
瓦西尼斯公司 |
在乳腺癌和膀胱癌中差异表达的基因及编码多肽
|
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
CA2490758C
(en)
|
2002-07-15 |
2014-09-23 |
Genentech, Inc. |
Dosage form of recombinant humanized monoclonal antibody 2c4
|
|
ATE536188T1
(de)
|
2002-08-14 |
2011-12-15 |
Macrogenics Inc |
Fcgammariib-spezifische antikörper und verfahren zur verwendung davon
|
|
ES2562177T3
(es)
|
2002-09-27 |
2016-03-02 |
Xencor Inc. |
Variantes de Fc optimizadas y métodos para su generación
|
|
RS20050300A
(en)
|
2002-10-16 |
2007-08-03 |
Euro-Celtique S.A., |
Antibodies that bind cell-associated ca 125/0772p and methods of use thereof
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
JP2006522811A
(ja)
|
2003-04-09 |
2006-10-05 |
ジェネンテック・インコーポレーテッド |
ＴＮＦαインヒビターに対して不十分な反応を示す患者の自己免疫疾患治療法
|
|
KR100835786B1
(ko)
|
2003-07-08 |
2008-06-09 |
제넨테크, 인크. |
Ｉｌ-１７ａ／ｆ 이종 폴리펩티드 및 그의 치료 용도
|
|
US20050048617A1
(en)
|
2003-08-18 |
2005-03-03 |
Medimmune, Inc. |
Humanization of antibodies
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
WO2005040163A1
(en)
|
2003-10-28 |
2005-05-06 |
Dr. Reddy's Laboratories Ltd |
Heterocyclic compounds that block the effects of advanced glycation end products (age)
|
|
CA2747871C
(en)
|
2003-11-17 |
2018-04-10 |
Genentech, Inc. |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
|
NZ547438A
(en)
|
2003-12-19 |
2010-01-29 |
Genentech Inc |
Monovalent antibody fragments useful as therapeutics
|
|
HUE049161T2
(hu)
|
2003-12-23 |
2020-09-28 |
Genentech Inc |
Új anti-IL13 antitestek és alkalmazásaik
|
|
US20060122377A1
(en)
|
2004-02-19 |
2006-06-08 |
Genentech, Inc. |
CDR-repaired antibodies
|
|
EP1786463A4
(en)
|
2004-03-26 |
2009-05-20 |
Human Genome Sciences Inc |
ANTIBODY AGAINST NOGO RECEPTOR
|
|
AU2005232657B2
(en)
|
2004-04-08 |
2010-12-16 |
David B. Agus |
ErbB antagonists for pain therapy
|
|
EP3130349A1
(en)
|
2004-06-04 |
2017-02-15 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
|
GT200500155A
(es)
|
2004-06-16 |
2006-05-15 |
|
Terapia del càncer resistente al platino
|
|
CN102603895B
(zh)
|
2004-06-18 |
2016-09-28 |
Ambrx公司 |
新颖抗原结合多肽和其用途
|
|
EP2940043A1
(en)
|
2004-07-15 |
2015-11-04 |
Xencor, Inc. |
Optimized fc variants
|
|
JP4947717B2
(ja)
|
2004-07-20 |
2012-06-06 |
ジェネンテック， インコーポレイテッド |
アンジオポエチン様４タンパク質のインヒビター、組み合わせ、およびそれらの使用
|
|
KR20150043558A
(ko)
|
2004-07-22 |
2015-04-22 |
제넨테크, 인크. |
Ｈｅｒ２ 항체 조성물
|
|
WO2006014928A1
(en)
|
2004-07-26 |
2006-02-09 |
Genentech, Inc. |
Methods and compositions for modulating hepatocyte growth factor activation
|
|
ES2377979T3
(es)
|
2004-09-03 |
2012-04-03 |
Genentech, Inc. |
Antagonistas anti-beta7 humanizados y utilizaciones para los mismos
|
|
EP1793850A4
(en)
|
2004-09-21 |
2010-06-30 |
Medimmune Inc |
ANTIBODIES TO THE METHOD AND METHOD FOR THE PRODUCTION OF VACCINES AGAINST THE RESPIRATORY SYNCYTIAL VIRUS
|
|
AU2005286607B2
(en)
|
2004-09-23 |
2011-01-27 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
EP2422811A2
(en)
|
2004-10-27 |
2012-02-29 |
MedImmune, LLC |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
CN102746404B
(zh)
|
2004-11-12 |
2016-01-20 |
赞科股份有限公司 |
对FcRn的结合被改变的Fc变体
|
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
|
DK1841793T3
(da)
|
2005-01-07 |
2010-07-19 |
Diadexus Inc |
Ovr110-antistofsammensætninger og fremgangsmåder til anvendelse deraf
|
|
CN102580084B
(zh)
|
2005-01-21 |
2016-11-23 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
|
AU2006214121B9
(en)
|
2005-02-15 |
2013-02-14 |
Duke University |
Anti-CD19 antibodies and uses in oncology
|
|
SI1850874T1
(sl)
|
2005-02-23 |
2014-01-31 |
Genentech, Inc. |
Podaljšanje časa za napredovanje bolezni ali za preživetje pri pacientkah z rakom na jajčnikih ob uporabi pertuzumaba
|
|
EP1869192B1
(en)
|
2005-03-18 |
2016-01-20 |
MedImmune, LLC |
Framework-shuffling of antibodies
|
|
US20090220495A1
(en)
|
2005-04-07 |
2009-09-03 |
Abdallah Fanidi |
Cancer Related Genes (PRLR)
|
|
US20090214536A1
(en)
|
2005-04-07 |
2009-08-27 |
Guoying Yu |
CACNA1E in Cancer Diagnosis, Detection and Treatment
|
|
EP2221316A1
(en)
|
2005-05-05 |
2010-08-25 |
Duke University |
Anti-CD19 antibody therapy for autoimmune disease
|
|
CN101198624B
(zh)
|
2005-05-06 |
2012-10-10 |
津莫吉尼蒂克斯公司 |
Il-31单克隆抗体及使用方法
|
|
US7858843B2
(en)
|
2005-06-06 |
2010-12-28 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
CA2613512A1
(en)
|
2005-06-23 |
2007-01-04 |
Medimmune, Inc. |
Antibody formulations having optimized aggregation and fragmentation profiles
|
|
CN104072614B
(zh)
|
2005-07-08 |
2017-04-26 |
生物基因Ma公司 |
抗-αvβ6 抗体及其用途
|
|
US7931902B2
(en)
|
2005-08-15 |
2011-04-26 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
US9168286B2
(en)
|
2005-10-13 |
2015-10-27 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of patients with autoantibody positive disease
|
|
WO2007056227A2
(en)
|
2005-11-04 |
2007-05-18 |
Genentech, Inc. |
Use of complement pathway inhibitors to treat ocular diseases
|
|
BRPI0618338A2
(pt)
|
2005-11-07 |
2011-08-23 |
Scripps Resarch Inst |
uso de inibidor de sinalização de fator tecidual, método para identificar um agente que inibe a sinalização de tf/viia, composições farmacêuticas e kit
|
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
|
CA2630432A1
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
JP5808070B2
(ja)
|
2005-12-02 |
2015-11-10 |
ジェネンテック， インコーポレイテッド |
結合ポリペプチド及びその使用
|
|
CA2631961A1
(en)
|
2005-12-02 |
2007-11-08 |
Genentech, Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling relating to antibodies that bind to il-22
|
|
EP1973948B1
(en)
|
2005-12-15 |
2015-02-11 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
|
ES2526204T3
(es)
|
2006-01-05 |
2015-01-08 |
Genentech, Inc. |
Anticuerpos anti-EphB4 y métodos para usar los mismos
|
|
EP2050335A1
(en)
|
2006-02-17 |
2009-04-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
EP1999148B8
(en)
|
2006-03-06 |
2014-03-05 |
Medlmmune, LLC |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CA2644743C
(en)
|
2006-03-08 |
2015-05-19 |
Waldemar Debinski |
Soluble monomeric ephrin a1
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
CN101437536A
(zh)
|
2006-03-23 |
2009-05-20 |
诺华有限公司 |
抗肿瘤细胞抗原抗体治疗
|
|
WO2007123765A2
(en)
|
2006-03-31 |
2007-11-01 |
Human Genome Sciences Inc. |
Neutrokine-alpha and neutrokine-alpha splice variant
|
|
EP2614839A3
(en)
|
2006-04-05 |
2015-01-28 |
Genentech, Inc. |
Method for using BOC/CDO to modulate hedgehog signaling
|
|
TW200813231A
(en)
|
2006-04-13 |
2008-03-16 |
Novartis Vaccines & Diagnostic |
Methods of treating, diagnosing or detecting cancer
|
|
US20090288176A1
(en)
|
2006-04-19 |
2009-11-19 |
Genentech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
|
TWI523864B
(zh)
|
2006-05-30 |
2016-03-01 |
建南德克公司 |
抗體及免疫接合物及其用途
|
|
PL2029173T3
(pl)
|
2006-06-26 |
2017-04-28 |
Macrogenics, Inc. |
Przeciwciała swoiste dla FC RIIB i sposoby ich zastosowania
|
|
US7572618B2
(en)
|
2006-06-30 |
2009-08-11 |
Bristol-Myers Squibb Company |
Polynucleotides encoding novel PCSK9 variants
|
|
AU2007272995B2
(en)
|
2006-07-10 |
2013-02-07 |
Biogen Idec Ma Inc. |
Compositions and methods for inhibiting growth of smad4-deficient cancers
|
|
AU2007285976B2
(en)
|
2006-08-14 |
2011-08-18 |
Xencor, Inc |
Optimized antibodies that target CD19
|
|
EP2423332A1
(en)
|
2006-08-25 |
2012-02-29 |
Oncotherapy Science, Inc. |
Prognostic markers and therapeutic targets for lung cancer
|
|
CA2660175C
(en)
|
2006-09-01 |
2015-05-12 |
Zymogenetics, Inc. |
Variable region sequences of il-31 monoclonal antibodies and methods of use
|
|
ES2530438T3
(es)
|
2006-09-12 |
2015-03-02 |
Genentech Inc |
Procedimientos y composiciones para el diagnóstico y tratamiento del cáncer de pulmón utilizando el gen de KIT o KDR como marcador genético
|
|
EP2064335A4
(en)
|
2006-10-16 |
2011-03-30 |
Medimmune Llc |
MOLECULES WITH REDUCED HALF TIME, COMPOSITIONS AND ITS USE
|
|
PT2061814E
(pt)
|
2006-10-27 |
2012-09-10 |
Genentech Inc |
Anticorpos e imunoconjugados e suas utilizações
|
|
WO2008067283A2
(en)
|
2006-11-27 |
2008-06-05 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
|
WO2008076960A2
(en)
|
2006-12-18 |
2008-06-26 |
Genentech, Inc. |
Antagonist anti-notch3 antibodies and their use in the prevention and treatment of notch3-related diseases
|
|
RU2009133784A
(ru)
|
2007-02-09 |
2011-03-20 |
Дженентек, Инк. (Us) |
АНТИ-Robo4-АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
|
AU2008223069B2
(en)
|
2007-03-02 |
2012-12-13 |
F. Hoffmann-La Roche Ag |
Predicting response to a HER dimerisation inhibitor based on low HER3 expression
|
|
EP2125898B1
(en)
|
2007-03-14 |
2013-05-15 |
Novartis AG |
Apcdd1 inhibitors for treating, diagnosing or detecting cancer
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
JP5456658B2
(ja)
|
2007-03-30 |
2014-04-02 |
メディミューン，エルエルシー |
抗体製剤
|
|
TWI570135B
(zh)
|
2007-04-27 |
2017-02-11 |
建南德克公司 |
高效、穩定且非免疫抑制之抗－ｃｄ４抗體
|
|
EP2164868B1
(en)
|
2007-05-04 |
2015-03-25 |
Technophage, Investigação E Desenvolvimento Em Biotecnologia, SA |
Engineered rabbit antibody variable domains and uses thereof
|
|
US20080279851A1
(en)
|
2007-05-07 |
2008-11-13 |
Medlmmune, Llc |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
LT2176298T
(lt)
|
2007-05-30 |
2018-04-10 |
Xencor, Inc. |
Būdai ir kompozicijos, skirti cd32b ekspresuojančių ląstelių slopinimui
|
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
|
EP2171090B1
(en)
|
2007-06-08 |
2013-04-03 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
PE20140625A1
(es)
|
2007-07-16 |
2014-05-29 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS
|
|
EP2474557B1
(en)
|
2007-07-16 |
2014-08-20 |
Genentech, Inc. |
Anti-CD79b antibodies and immunoconjugates and methods of use
|
|
EP2190478B1
(en)
|
2007-08-24 |
2016-03-23 |
Oncotherapy Science, Inc. |
Dkk1 oncogene as therapeutic target for cancer and a diagnosing marker
|
|
JP2010536365A
(ja)
|
2007-08-24 |
2010-12-02 |
オンコセラピー・サイエンス株式会社 |
前立腺癌の治療及び診断の標的遺伝子のための、ｐｋｉｂ及びｎａａｌａｄｌ２
|
|
NZ583605A
(en)
|
2007-08-29 |
2012-10-26 |
Sanofi Aventis |
Humanized anti-cxcr5 antibodies, derivatives thereof and their uses
|
|
US20100226925A1
(en)
|
2007-09-14 |
2010-09-09 |
Amgen Inc. |
Homogeneous Antibody Populations
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
DK2220116T3
(da)
|
2007-11-12 |
2012-11-26 |
Theraclone Sciences Inc |
Sammensætninger og fremgangsmåder til terapien og diagnosticeringen af influenza
|
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-ｖｅｇｆ抗體
|
|
AU2008341050B2
(en)
|
2007-12-26 |
2013-10-24 |
Vaccinex, Inc. |
Anti-C35 antibody combination therapies and methods
|
|
PL2235059T3
(pl)
|
2007-12-26 |
2015-08-31 |
Xencor Inc |
Warianty FC o zmodyfikowanym wiązaniu do FCRN
|
|
AU2009203350B2
(en)
|
2008-01-11 |
2014-03-13 |
Gene Techno Science Co., Ltd. |
Humanized anti-alpha9 integrin antibodies and the uses thereof
|
|
AU2009205995B2
(en)
|
2008-01-18 |
2014-04-03 |
Medimmune, Llc |
Cysteine engineered antibodies for site-specific conjugation
|
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
|
|
RU2553566C2
(ru)
|
2008-01-31 |
2015-06-20 |
Дженентек, Инк. |
АНТИ-CD79b АНТИТЕЛА И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
PL2250279T3
(pl)
|
2008-02-08 |
2016-11-30 |
|
Przeciwciała anty-ifnar1 o zmniejszonym powinowactwie do liganda fc
|
|
JP5544309B2
(ja)
|
2008-03-10 |
2014-07-09 |
セラクローン サイエンシーズ， インコーポレイテッド |
サイトメガロウイルス感染の治療および診断のための組成物および方法
|
|
CA2719189C
(en)
|
2008-04-09 |
2020-08-04 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
|
KR101746861B1
(ko)
|
2008-04-24 |
2017-06-14 |
가부시키가이샤 진 테크노 사이언스 |
세포 외 기질 단백질의 아미노산 서열 ｒｇｄ에 특이적인 인간화된 항체 및 그의 용도
|
|
US9169296B2
(en)
|
2008-05-29 |
2015-10-27 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Expression and assembly of human group C rotavirus-like particles and uses thereof
|
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
|
RU2011103199A
(ru)
|
2008-06-30 |
2012-08-10 |
Онкотерапи Сайенс, Инк. (Jp) |
Антитела против cdh3, меченные радиоизотопной меткой, и их применение
|
|
ES2442024T3
(es)
|
2008-07-15 |
2014-02-07 |
Academia Sinica |
Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
|
|
RU2478648C2
(ru)
|
2008-09-07 |
2013-04-10 |
Гликонекс Инк. |
Антитело против удлиненного гликосфинголипида i типа, его производные и применение
|
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
|
EP2350270B1
(en)
|
2008-10-24 |
2018-03-07 |
The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services |
Human ebola virus species and compositions and methods thereof
|
|
BRPI0921845A2
(pt)
|
2008-11-12 |
2019-09-17 |
Medimmune Llc |
formulação aquosa estéril estável, forma de dosagem unitária farmacêutica, seringa pré-carregada, e, métodos para tratar uma doença ou distúrbio, para tratar ou prevenir rejeição, para esgotar células t que expressam icos em um paciente humano, e para interromper arquitetura central germinal em um órgão linfóide secundário de um primata
|
|
WO2010087927A2
(en)
|
2009-02-02 |
2010-08-05 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
JP5936112B2
(ja)
|
2009-02-11 |
2016-06-15 |
アルブミディクス アクティーゼルスカブ |
アルブミン変異体及び複合体
|
|
EP2396035A4
(en)
|
2009-02-12 |
2012-09-12 |
Human Genome Sciences Inc |
USE OF ANTAGONISTS OF PROTEIN STIMULATING LYMPHOCYTES B TO PROMOTE GRAFT TOLERANCE
|
|
WO2010104208A1
(en)
|
2009-03-10 |
2010-09-16 |
Gene Techno Science Co., Ltd. |
Generation, expression and characterization of the humanized k33n monoclonal antibody
|
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
|
MY152068A
(en)
|
2009-03-20 |
2014-08-15 |
Genentech Inc |
Bispecific anti-her antibodies
|
|
BRPI1006448B1
(pt)
|
2009-03-25 |
2021-08-17 |
Genentech, Inc |
Anticorpo antagonista anti-fgfr3, anticorpo monoclonal, polinucleotídeo, vetor, microorganismo transgênico, método para produção de um anticorpo anti-fgfr3, formulação farmacêutica e usos do anticorpo antagonista anti-fgfr3
|
|
AU2010236787A1
(en)
|
2009-04-01 |
2011-11-10 |
Genentech, Inc. |
Anti-FcRH5 antibodies and immunoconjugates and methods of use
|
|
RU2598248C2
(ru)
|
2009-04-02 |
2016-09-20 |
Роше Гликарт Аг |
Полиспецифичные антитела, включающие антитела полной длины и одноцепочечные фрагменты fab
|
|
US9296785B2
(en)
|
2009-04-17 |
2016-03-29 |
Wake Forest University Health Sciences |
IL-13 receptor binding peptides
|
|
US8858948B2
(en)
|
2009-05-20 |
2014-10-14 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
|
WO2010136569A1
(en)
|
2009-05-29 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
|
RU2569186C2
(ru)
|
2009-06-04 |
2015-11-20 |
Новартис Аг |
СПОСОБЫ ИДЕНТИФИКАЦИИ САЙТОВ ДЛЯ КОНЪЮГАЦИИ IgG
|
|
EP2445520A4
(en)
|
2009-06-22 |
2013-03-06 |
Medimmune Llc |
MANIPULATED FC REGIONS FOR LOCAL SPECIFIC CONJUGATION
|
|
KR101962476B1
(ko)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
면역성 접합체 및 그 제조방법
|
|
ES2513292T3
(es)
|
2009-07-31 |
2014-10-24 |
Genentech, Inc. |
Inhibición de metástasis tumoral usando anticuerpos anti-G-CSF
|
|
DK2473522T3
(en)
|
2009-09-02 |
2016-11-28 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
RU2573915C2
(ru)
|
2009-09-16 |
2016-01-27 |
Дженентек, Инк. |
Содержащие суперспираль и/или привязку белковые комплексы и их применение
|
|
HUE026447T2
(en)
|
2009-10-16 |
2016-05-30 |
Novartis Ag |
Pharmacodynamic tumor response biomarkers
|
|
JP5889794B2
(ja)
|
2009-10-19 |
2016-03-22 |
ジェネンテック， インコーポレイテッド |
肝細胞増殖因子アクチベーターの調節
|
|
EP2491059B1
(en)
|
2009-10-22 |
2015-02-25 |
F.Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods using same
|
|
KR20120105446A
(ko)
|
2009-10-22 |
2012-09-25 |
제넨테크, 인크. |
대식세포-자극 단백질의 헵신 활성화를 조정하기 위한 방법 및 조성물
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
|
EP2493921B1
(en)
|
2009-10-30 |
2018-09-26 |
Albumedix Ltd |
Albumin variants
|
|
US8361744B2
(en)
|
2009-11-05 |
2013-01-29 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
|
NZ599707A
(en)
|
2009-11-30 |
2014-07-25 |
Genentech Inc |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211 = seqid2 )
|
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
RU2016105962A
(ru)
|
2009-12-04 |
2018-11-23 |
Дженентек, Инк. |
Мультиспецифические антитела, аналоги антител, композиции и способы
|
|
TWI505836B
(zh)
|
2009-12-11 |
2015-11-01 |
Genentech Inc |
抗－ｖｅｇｆ－ｃ抗體及其使用方法
|
|
US9023996B2
(en)
|
2009-12-23 |
2015-05-05 |
Synimmune Gmbh |
Anti-FLT3 antibodies
|
|
KR101961495B1
(ko)
|
2009-12-23 |
2019-03-22 |
아비펩 피티와이 리미티트 |
면역-컨쥬게이트 및 그 제조방법 ２
|
|
AR079704A1
(es)
|
2009-12-23 |
2012-02-15 |
Genentech Inc |
Anticuerpos anti-bv8 y sus usos
|
|
DK2519542T3
(en)
|
2009-12-28 |
2019-01-14 |
Onco Therapy Science Inc |
ANTI-CDH3 ANTIBODIES AND APPLICATIONS THEREOF.
|
|
WO2011089211A1
(en)
|
2010-01-22 |
2011-07-28 |
Synimmune Gmbh |
Anti-cd133 antibodies and methods of using the same
|
|
CN102933231B
(zh)
|
2010-02-10 |
2015-07-29 |
伊缪诺金公司 |
Cd20抗体及其用途
|
|
CN102892779B
(zh)
|
2010-02-18 |
2016-12-21 |
基因泰克公司 |
神经调节蛋白拮抗剂及其在治疗癌症中的用途
|
|
WO2011106297A2
(en)
|
2010-02-23 |
2011-09-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
|
CN102971340A
(zh)
|
2010-03-29 |
2013-03-13 |
酵活有限公司 |
具有增强的或抑制的效应子功能的抗体
|
|
KR20130070576A
(ko)
|
2010-04-09 |
2013-06-27 |
노보자임스 바이오파마 디케이 에이/에스 |
알부민 유도체 및 변이체
|
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
EP2560683B2
(en)
|
2010-04-23 |
2022-07-20 |
F. Hoffmann-La Roche AG |
Production of heteromultimeric proteins
|
|
CN107090045A
(zh)
|
2010-05-03 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
用于肿瘤诊断和治疗的组合物和方法
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
EP2576622A4
(en)
|
2010-06-01 |
2013-11-27 |
Univ Monash |
ANTIBODIES AGAINST RECEPTOR TYROSINE KINASE C-MET
|
|
NZ602840A
(en)
|
2010-06-03 |
2014-11-28 |
Genentech Inc |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
US9315585B2
(en)
|
2010-06-19 |
2016-04-19 |
Memorial Sloan Kettering Cancer Center |
Anti-GD2 antibodies
|
|
CA2806252C
(en)
|
2010-07-29 |
2019-05-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
|
JP2013540701A
(ja)
|
2010-08-12 |
2013-11-07 |
セラクローン サイエンシーズ， インコーポレイテッド |
抗赤血球凝集素抗体組成物およびその使用方法
|
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
|
WO2012025530A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
|
PE20140190A1
(es)
|
2010-08-27 |
2014-02-10 |
Stem Centrx Inc |
Moduladores de proteinas notum y metodos de uso
|
|
EP2611465A4
(en)
|
2010-08-31 |
2014-06-04 |
Theraclone Sciences Inc |
NEUTRALIZING ANTI-VIRUS ANTIBODIES FOR HUMAN IMMUNODEFICIENCY (HIV)
|
|
US9458231B2
(en)
|
2010-09-03 |
2016-10-04 |
Stemcentrx, Inc. |
Modulators and methods of use
|
|
US9085621B2
(en)
|
2010-09-10 |
2015-07-21 |
Apexigen, Inc. |
Anti-IL-1β antibodies
|
|
IL290591B2
(en)
|
2010-09-29 |
2024-08-01 |
Seagen Inc |
Antibody drug preparations (ADC) that bind to 191P4D12 proteins
|
|
EP3219731A1
(en)
|
2010-10-01 |
2017-09-20 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
EP2635674A4
(en)
|
2010-11-05 |
2014-11-05 |
Transbio Ltd |
MARKERS FOR ENDOTHELIAL STORAGE CELLS AND USES THEREOF
|
|
AU2011325833C1
(en)
|
2010-11-05 |
2017-07-13 |
Zymeworks Bc Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
|
BR112013014321A2
(pt)
|
2010-12-08 |
2019-09-24 |
Stem Centrx Inc |
moduladores inovadores e métodos de uso
|
|
ES2720136T3
(es)
|
2010-12-22 |
2019-07-18 |
Teva Pharmaceuticals Australia Pty Ltd |
Anticuerpo modificado con semivida mejorada
|
|
JP5766296B2
(ja)
|
2010-12-23 |
2015-08-19 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
MX355255B
(es)
|
2011-02-04 |
2018-04-11 |
Genentech Inc |
Variantes de fc y métodos para su producción.
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
EP2673297A2
(en)
|
2011-02-11 |
2013-12-18 |
Zyngenia, Inc. |
Monovalent and multivalent multispecific complexes and uses thereof
|
|
BR112013020743A2
(pt)
|
2011-02-14 |
2016-10-18 |
Theraclone Sciences Inc |
composições e métodos para a terapia e diagnóstico de influenza
|
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
|
AU2012223449A1
(en)
|
2011-03-03 |
2013-05-02 |
Apexigen, Inc. |
Anti-IL-6 receptor antibodies and methods of use
|
|
JP5832559B2
(ja)
|
2011-03-10 |
2015-12-16 |
オメロス コーポレーション |
ｅｘｖｉｖｏにおける加速された抗体進化による抗ＦＮ１４モノクローナル抗体の生成
|
|
JP2014509591A
(ja)
|
2011-03-15 |
2014-04-21 |
セラクローン サイエンシーズ， インコーポレイテッド |
インフルエンザの治療および診断のための組成物および方法
|
|
EP2686014A1
(en)
|
2011-03-16 |
2014-01-22 |
Sanofi |
Uses of a dual v region antibody-like protein
|
|
AU2012245073B2
(en)
|
2011-04-21 |
2016-02-11 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using them b
|
|
CN106928362B
(zh)
|
2011-04-29 |
2021-10-26 |
埃派斯进有限公司 |
抗-cd40抗体及其使用方法
|
|
CA2837169C
(en)
|
2011-05-24 |
2021-11-09 |
Zyngenia, Inc. |
Multispecific complexes comprising angiopoietin-2-binding peptide and their uses
|
|
EA028220B1
(ru)
|
2011-05-27 |
2017-10-31 |
Глаксо Груп Лимитед |
Иммуноконъюгат на основе белка, связывающегося с bcma (cd269/tnfrsf17), его медицинское применение и фармацевтическая композиция
|
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
|
WO2012170740A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
|
EP3392274A1
(en)
|
2011-08-12 |
2018-10-24 |
Omeros Corporation |
Anti-fzd10 monoclonal antibodies and methods for their use
|
|
MX2014001736A
(es)
|
2011-08-17 |
2014-03-31 |
Genentech Inc |
Inhibicion de angiogenesis en tumores refractarios.
|
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
|
DK2744931T3
(en)
|
2011-08-18 |
2018-08-06 |
Affinity Biosciences Pty Ltd |
SOLUBLE POLYPEPTIDES
|
|
WO2013033069A1
(en)
|
2011-08-30 |
2013-03-07 |
Theraclone Sciences, Inc. |
Human rhinovirus (hrv) antibodies
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
CA2849705A1
(en)
|
2011-09-23 |
2013-03-28 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Modified albumin-binding domains and uses thereof to improve pharmacokinetics
|
|
DK2766392T3
(da)
|
2011-10-10 |
2019-10-07 |
Xencor Inc |
Fremgangsmåde til oprensning af antistoffer
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
DK2771022T3
(da)
|
2011-10-11 |
2020-09-28 |
Viela Bio Inc |
Cd40l-specifikke tn3-afledte skeletter (scaffolds) og fremgangsmåder til anvendelse deraf
|
|
US9327023B2
(en)
|
2011-10-25 |
2016-05-03 |
The Regents Of The University Of Michigan |
HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
|
|
AU2012328980A1
(en)
|
2011-10-28 |
2014-04-24 |
Genentech, Inc. |
Therapeutic combinations and methods of treating melanoma
|
|
WO2013067055A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Methods of blocking cancer stem cell growth
|
|
WO2013067054A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Antibodies and methods of treating cancer
|
|
EP2773664A1
(en)
|
2011-11-01 |
2014-09-10 |
Bionomics, Inc. |
Anti-gpr49 antibodies
|
|
US9221907B2
(en)
|
2011-11-01 |
2015-12-29 |
Bionomics Inc. |
Anti-GPR49 monoclonal antibodies
|
|
KR102027603B1
(ko)
|
2011-11-02 |
2019-10-01 |
아펙시젠, 인코포레이티드 |
항-kdr 항체 및 사용 방법
|
|
CA2854233C
(en)
|
2011-11-04 |
2020-05-12 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
|
US20140315817A1
(en)
|
2011-11-18 |
2014-10-23 |
Eleven Biotherapeutics, Inc. |
Variant serum albumin with improved half-life and other properties
|
|
KR20140125351A
(ko)
|
2011-11-23 |
2014-10-28 |
이제니카 바이오테라퓨틱스, 인크. |
항-cd98 항체 및 이의 사용 방법
|
|
SG11201402510TA
(en)
|
2011-11-30 |
2014-06-27 |
Genentech Inc |
Erbb3 mutations in cancer
|
|
WO2013081993A1
(en)
|
2011-12-02 |
2013-06-06 |
Eli Lilly And Company |
Anti-glucagon antibodies and uses thereof
|
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
WO2013093809A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
|
US20130195851A1
(en)
|
2011-12-23 |
2013-08-01 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
|
EP2802601B1
(en)
|
2012-01-09 |
2019-11-13 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
CN104520321A
(zh)
|
2012-01-09 |
2015-04-15 |
斯克利普斯研究所 |
超长互补决定区及其用途
|
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
|
EP3196214B1
(en)
|
2012-02-15 |
2019-07-31 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (trem-1)
|
|
EP2814842B1
(en)
|
2012-02-15 |
2018-08-22 |
Novo Nordisk A/S |
Antibodies that bind peptidoglycan recognition protein 1
|
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
|
PE20150090A1
(es)
|
2012-02-24 |
2015-02-16 |
Stem Centrx Inc |
Moduladores y metodos de empleo novedosos referencia cruzada a solicitudes
|
|
PL2825556T3
(pl)
|
2012-03-16 |
2018-10-31 |
Albumedix A/S |
Warianty albuminy
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
JP2015514710A
(ja)
|
2012-03-27 |
2015-05-21 |
ジェネンテック， インコーポレイテッド |
Ｈｅｒ３阻害剤に関する診断及び治療
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
EP2844300B1
(en)
|
2012-05-01 |
2018-10-17 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
|
WO2013169734A1
(en)
|
2012-05-07 |
2013-11-14 |
Amgen Inc. |
Anti-erythropoietin antibodies
|
|
EP2847230B1
(en)
|
2012-05-10 |
2020-08-12 |
Zymeworks Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
MX354862B
(es)
|
2012-06-27 |
2018-03-23 |
Hoffmann La Roche |
Método para la producción de entidades dirigidas altamente selectivas hechas a la medida y biespecíficas que contienen dos entidades de unión diferentes.
|
|
MX2014014804A
(es)
|
2012-06-27 |
2015-02-12 |
Hoffmann La Roche |
Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
|
|
BR112014030843A2
(pt)
|
2012-07-04 |
2019-10-15 |
Hoffmann La Roche |
anticorpo anti-teofilina, formulação farmacêutica e uso do anticorpo
|
|
EP2870180B1
(en)
|
2012-07-04 |
2024-08-28 |
F. Hoffmann-La Roche AG |
Anti-biotin antibodies and methods of use
|
|
SI2869848T1
(sl)
|
2012-07-04 |
2017-01-31 |
F. Hoffmann-La Roche Ag |
Kovalentno vezani konjugati antigen-protitelo
|
|
AU2013306098A1
(en)
|
2012-08-18 |
2015-02-12 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
|
EP2888279A1
(en)
|
2012-08-22 |
2015-07-01 |
Glaxo Group Limited |
Anti lrp6 antibodies
|
|
US8968742B2
(en)
|
2012-08-23 |
2015-03-03 |
Agensys, Inc. |
Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
|
|
AU2013329311A1
(en)
|
2012-10-09 |
2015-04-30 |
Igenica Biotherapeutics, Inc. |
Anti-C16orf54 antibodies and methods of use thereof
|
|
EP2914627B1
(en)
|
2012-10-30 |
2021-04-07 |
Apexigen, Inc. |
Anti-cd40 antibodies and methods of use
|
|
GB2512156A
(en)
|
2012-11-08 |
2014-09-24 |
Novozymes Biopharma Dk As |
Albumin variants
|
|
MX363188B
(es)
|
2012-11-30 |
2019-03-13 |
Hoffmann La Roche |
Identificación de pacientes con necesidad de coterapia del inhibidor de pd-l1.
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP3620473A1
(en)
|
2013-01-14 |
2020-03-11 |
Xencor, Inc. |
Novel heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
EP2945969A1
(en)
|
2013-01-15 |
2015-11-25 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
BR112015022019A2
(pt)
|
2013-03-14 |
2017-08-29 |
Genentech Inc |
Anticorpos isolados, ácido nucleico, célula hospedeira, método de produção de anticorpos, imunoconjugado, formulação farmacêutica, métodos de tratamento de indivíduos, de inibição da proliferação de células, de detecção de b7-h4 humano e de detecção de câncer
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
WO2014143739A2
(en)
|
2013-03-15 |
2014-09-18 |
Biogen Idec Ma Inc. |
Anti-alpha v beta 6 antibodies and uses thereof
|
|
AU2014232416B2
(en)
|
2013-03-15 |
2017-09-28 |
Xencor, Inc. |
Modulation of T Cells with Bispecific Antibodies and FC Fusions
|
|
CA2903576C
(en)
|
2013-03-15 |
2021-06-08 |
Nai-Kong V. Cheung |
High affinity anti-gd2 antibodies
|
|
JP6594855B2
(ja)
|
2013-03-15 |
2019-10-23 |
ゼンコア インコーポレイテッド |
ヘテロ二量体タンパク質
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
BR112015023752B1
(pt)
|
2013-03-15 |
2023-11-14 |
Zyngenia, Inc. |
Domínio de reconhecimento modular (mrd), complexo compreendendo mrd e cetuximabe, usos do complexo para inibir a angiogênese e tratar câncer e composição farmacêutica compreendendo o dito complexo
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
WO2014144466A1
(en)
|
2013-03-15 |
2014-09-18 |
Biogen Idec Ma Inc. |
Anti-alpha v beta 6 antibodies and uses thereof
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
US20160052993A1
(en)
|
2013-05-03 |
2016-02-25 |
Eleven Biotherapeutics, Inc. |
Albumin variants binding to fcrn
|
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
|
WO2014210564A1
(en)
|
2013-06-27 |
2014-12-31 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
EP3022224A2
(en)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
AU2014290361B2
(en)
|
2013-07-18 |
2019-04-18 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementarity determining regions
|
|
WO2015017552A1
(en)
|
2013-08-01 |
2015-02-05 |
Agensys, Inc. |
Antibody drug conjugates (adc) that bind to cd37 proteins
|
|
MX2016001854A
(es)
|
2013-08-12 |
2016-09-06 |
Genentech Inc |
Composiciones y metodo para tratar condiciones asociadas con el complemento.
|
|
AU2014312310A1
(en)
|
2013-08-28 |
2016-04-07 |
Abbvie Stemcentrx Llc |
Novel SEZ6 modulators and methods of use
|
|
JP6486368B2
(ja)
|
2013-09-06 |
2019-03-20 |
アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ |
改変されたグリコシル基を含む糖脂質を用いたヒトｉＮＫＴ細胞の活性化
|
|
AR097685A1
(es)
|
2013-09-17 |
2016-04-06 |
Genentech Inc |
Métodos de uso de anticuerpos anti-lgr5
|
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
|
MX2016004579A
(es)
|
2013-10-10 |
2016-12-09 |
Beth Israel Deaconess Medical Ct Inc |
Proteinas de union del miembro 1 de la familia de transmembrana 4 l-seis (tm4sf1) y metodos de uso de las mismas.
|
|
EA036927B1
(ru)
|
2013-10-11 |
2021-01-15 |
Оксфорд Биотерепьютикс Лтд |
Конъюгированные антитела против ly75 для лечения рака
|
|
WO2015070210A1
(en)
|
2013-11-11 |
2015-05-14 |
Wake Forest University Health Sciences |
Epha3 and multi-valent targeting of tumors
|
|
CN110590950A
(zh)
|
2013-12-13 |
2019-12-20 |
基因泰克公司 |
抗cd33抗体和免疫缀合物
|
|
BR112016013861A2
(pt)
|
2013-12-16 |
2017-10-10 |
Genentech Inc |
conjugados de droga e anticorpo, compostos, método de tratamento e composição farmacêutica
|
|
RU2682754C2
(ru)
|
2014-01-03 |
2019-03-21 |
Ф. Хоффманн-Ля Рош Аг |
Конъюгаты полипептидного токсина и антитела, соединенных ковалентной связью
|
|
PL3089996T3
(pl)
|
2014-01-03 |
2021-12-13 |
F. Hoffmann-La Roche Ag |
Dwuswoiste przeciwciała przeciw haptenowi/przeciw receptorowi występującemu w barierze krew-mózg, ich kompleksy i ich zastosowanie jako przenośniki wahadłowe występujące w barierze krew-mózg
|
|
CN105873615B
(zh)
|
2014-01-03 |
2020-12-25 |
豪夫迈·罗氏有限公司 |
共价连接的helicar-抗helicar抗体缀合物及其用途
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US9982041B2
(en)
|
2014-01-16 |
2018-05-29 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
JP2017505305A
(ja)
|
2014-01-24 |
2017-02-16 |
ジェネンテック， インコーポレイテッド |
抗ｓｔｅａｐ１抗体及びイムノコンジュゲートを使用する方法
|
|
ES2694857T3
(es)
|
2014-02-04 |
2018-12-27 |
Genentech, Inc. |
Smoothened mutante y métodos de uso de la misma
|
|
AU2015231001A1
(en)
|
2014-03-21 |
2016-09-29 |
Abbvie Inc. |
Anti-EGFR antibodies and antibody drug conjugates
|
|
EP3129767B1
(en)
|
2014-03-27 |
2021-09-01 |
Academia Sinica |
Reactive labelling compounds and uses thereof
|
|
CN111410691B
(zh)
|
2014-03-28 |
2024-02-13 |
Xencor公司 |
结合至cd38和cd3的双特异性抗体
|
|
AU2015240599B2
(en)
|
2014-04-04 |
2020-11-19 |
Bionomics, Inc. |
Humanized antibodies that bind LGR5
|
|
RU2016144176A
(ru)
|
2014-04-11 |
2018-05-14 |
МЕДИММЬЮН, ЭлЭлСи |
Биспецифические антитела к her2
|
|
CN106471117A
(zh)
|
2014-05-06 |
2017-03-01 |
豪夫迈·罗氏有限公司 |
使用哺乳动物细胞产生异多聚体蛋白
|
|
US20170267780A1
(en)
|
2014-05-16 |
2017-09-21 |
Medimmune, Llc |
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
|
|
JP2017522861A
(ja)
|
2014-05-22 |
2017-08-17 |
ジェネンテック， インコーポレイテッド |
抗ｇｐｃ３抗体及びイムノコンジュゲート
|
|
CN106661099A
(zh)
|
2014-05-27 |
2017-05-10 |
中央研究院 |
抗her2醣抗体及其用途
|
|
KR20240096599A
(ko)
|
2014-05-27 |
2024-06-26 |
아카데미아 시니카 |
항-ｃｄ20 글리코항체 및 이의 용도
|
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
CA2950423A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
WO2015184001A1
(en)
|
2014-05-28 |
2015-12-03 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
|
KR102465120B1
(ko)
|
2014-07-17 |
2022-11-10 |
노보 노르디스크 에이/에스 |
점도를 감소시키기 위한 trem-1 항체의 부위 지정 돌연변이유발
|
|
WO2016014984A1
(en)
|
2014-07-24 |
2016-01-28 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
ES2913865T3
(es)
|
2014-08-28 |
2022-06-06 |
Bioatla Inc |
Receptores de antígeno quimérico condicionalmente activos para células T modificadas
|
|
KR102422375B1
(ko)
|
2014-09-08 |
2022-07-18 |
아카데미아 시니카 |
당지질을 사용한 인간 iNKT 세포 활성화
|
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
MX2017003022A
(es)
|
2014-09-12 |
2017-05-12 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados.
|
|
CN114106185A
(zh)
|
2014-09-12 |
2022-03-01 |
基因泰克公司 |
抗her2抗体和免疫缀合物
|
|
TW201625688A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
經半胱胺酸改造之抗體及接合物
|
|
WO2016049214A1
(en)
|
2014-09-23 |
2016-03-31 |
Genentech, Inc. |
METHOD OF USING ANTI-CD79b IMMUNOCONJUGATES
|
|
BR112017006602A2
(pt)
|
2014-10-01 |
2017-12-19 |
Medimmune Llc |
método de conjugação de um polipeptídeo
|
|
US10584175B2
(en)
|
2014-10-23 |
2020-03-10 |
La Trobe University |
FN14-binding proteins and uses thereof
|
|
RU2017119185A
(ru)
|
2014-11-05 |
2018-12-05 |
Дженентек, Инк. |
Антитела против fgfr2/3 и способы их применения
|
|
LT3223845T
(lt)
|
2014-11-26 |
2021-08-25 |
Xencor, Inc. |
Heterodimeriniai antikūnai, kurie suriša cd3 ir cd20
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
WO2016086196A2
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
KR20170094216A
(ko)
|
2014-12-17 |
2017-08-17 |
에프. 호프만-라 로슈 아게 |
소르타제를 사용하는 효소 매개되는 폴리펩티드 접합을 위한 신규한 방법
|
|
WO2016097313A1
(en)
|
2014-12-19 |
2016-06-23 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
|
EP3237449A2
(en)
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
ES2924394T3
(es)
|
2015-01-09 |
2022-10-06 |
Adalta Ltd |
Moléculas de unión a CXCR4
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
CN107430127B
(zh)
|
2015-01-24 |
2020-08-28 |
中央研究院 |
癌症标记及其使用方法
|
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
|
JP2018512597A
(ja)
|
2015-02-04 |
2018-05-17 |
ジェネンテック， インコーポレイテッド |
突然変異体スムースンド及びその使用方法
|
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
BR112017019062A2
(pt)
|
2015-03-09 |
2018-04-17 |
Agensys Inc |
conjugados de anticorpo-fármaco (adc) que se ligam a proteínas flt3
|
|
SG10201913158PA
(en)
|
2015-04-03 |
2020-02-27 |
Eureka Therapeutics Inc |
Constructs targeting afp peptide/mhc complexes and uses thereof
|
|
JP6952605B2
(ja)
|
2015-04-24 |
2021-10-20 |
ジェネンテック， インコーポレイテッド |
多特異性抗原結合タンパク質
|
|
AR105618A1
(es)
|
2015-05-29 |
2017-10-25 |
Genentech Inc |
Metilación del promotor del ligando al receptor de muerte programada (pd-l1) en cáncer
|
|
CA2985718A1
(en)
|
2015-06-24 |
2016-12-29 |
F. Hoffmann-La Roche Ag |
Anti-transferrin receptor antibodies with tailored affinity
|
|
EP3337816B1
(en)
|
2015-08-20 |
2024-02-14 |
Albumedix Ltd |
Albumin variants and conjugates
|
|
JP6861702B2
(ja)
|
2015-09-25 |
2021-04-21 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
ソルターゼ・コンジュゲート化ループを含む組換え免疫グロブリン重鎖およびそのコンジュゲート
|
|
WO2017050872A1
(en)
|
2015-09-25 |
2017-03-30 |
F. Hoffmann-La Roche Ag |
Transamidation employing sortase a in deep eutectic solvents
|
|
CN108138158B
(zh)
|
2015-09-25 |
2021-11-09 |
豪夫迈·罗氏有限公司 |
可溶性分选酶a
|
|
CN108138204B
(zh)
|
2015-09-25 |
2021-12-31 |
豪夫迈·罗氏有限公司 |
使用分选酶a生产硫酯的方法
|
|
EP4435105A2
(en)
|
2015-09-29 |
2024-09-25 |
Amgen Inc. |
Asgr inhibitors for reduzing cholesterol levels
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
PE20231655A1
(es)
|
2015-10-02 |
2023-10-17 |
Hoffmann La Roche |
Anticuerpos biespecificos contra el cd20 humano y el receptor de transferrina humano y metodos de uso
|
|
KR20180075537A
(ko)
|
2015-10-06 |
2018-07-04 |
제넨테크, 인크. |
다발성 경화증을 치료하기 위한 방법
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
WO2017066714A1
(en)
|
2015-10-16 |
2017-04-20 |
Compugen Ltd. |
Anti-vsig1 antibodies and drug conjugates
|
|
KR20180081532A
(ko)
|
2015-10-30 |
2018-07-16 |
알레타 바이오쎄라퓨틱스, 인크. |
암 치료용 조성물 및 방법
|
|
CN108472365A
(zh)
|
2015-10-30 |
2018-08-31 |
艾丽塔生物治疗剂公司 |
用于肿瘤转导的组合物和方法
|
|
US10227410B2
(en)
|
2015-12-07 |
2019-03-12 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and PSMA
|
|
CN108495653A
(zh)
|
2016-01-27 |
2018-09-04 |
免疫医疗有限责任公司 |
用于制备具有定义的糖基化模式抗体的方法
|
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
|
JP2019515876A
(ja)
|
2016-03-08 |
2019-06-13 |
アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ |
Ｎ−グリカンおよびそのアレイのモジュール合成のための方法
|
|
CN108697799A
(zh)
|
2016-03-22 |
2018-10-23 |
生态学有限公司 |
抗lgr5单克隆抗体的施用
|
|
WO2017167712A1
(en)
|
2016-03-30 |
2017-10-05 |
F. Hoffmann-La Roche Ag |
Improved sortase
|
|
KR102459684B1
(ko)
|
2016-04-15 |
2022-10-26 |
바이오아트라, 인코퍼레이티드 |
항 Axl항체 및 이의 면역접합체와 이것들의 용도
|
|
EP3454863A1
(en)
|
2016-05-10 |
2019-03-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
|
HRP20221298T1
(hr)
|
2016-05-13 |
2022-12-23 |
Bioatla, Inc. |
Anti-ror2 protutijela, fragmenti protutijela, njihovi imunokonjugati i njihove uporabe
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
CN109562168A
(zh)
|
2016-06-08 |
2019-04-02 |
艾伯维公司 |
抗cd98抗体及抗体药物偶联物
|
|
BR112018075630A2
(pt)
|
2016-06-08 |
2019-03-19 |
Abbvie Inc. |
anticorpos anti-cd98 e conjugados de fármaco de anticorpo
|
|
BR112018075649A2
(pt)
|
2016-06-08 |
2019-04-09 |
Abbvie Inc. |
anticorpos anti-b7-h3 e conjugados de fármaco de anticorpo
|
|
JP6751165B2
(ja)
|
2016-06-08 |
2020-09-02 |
アッヴィ・インコーポレイテッド |
抗ｂ７−ｈ３抗体及び抗体薬物コンジュゲート
|
|
CA3027044A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
FI3468997T3
(fi)
|
2016-06-08 |
2023-10-31 |
Xencor Inc |
Igg4:ään liittyvien sairauksien hoito anti-cd19-vasta-aineilla, jotka ristisitoutuvat cd32b:een
|
|
US10787518B2
(en)
|
2016-06-14 |
2020-09-29 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
KR20190020341A
(ko)
|
2016-06-28 |
2019-02-28 |
젠코어 인코포레이티드 |
소마토스타틴 수용체 2에 결합하는 이종이량체 항체
|
|
JP2019524706A
(ja)
|
2016-07-08 |
2019-09-05 |
ジェネンテック， インコーポレイテッド |
Ｍｕｃ１６陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質４（ｈｅ４）の使用
|
|
WO2018027204A1
(en)
|
2016-08-05 |
2018-02-08 |
Genentech, Inc. |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
|
CA3034057A1
(en)
|
2016-08-22 |
2018-03-01 |
CHO Pharma Inc. |
Antibodies, binding fragments, and methods of use
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
AU2017342560B2
(en)
|
2016-10-14 |
2022-03-17 |
Xencor, Inc. |
IL15/IL15Ralpha heterodimeric Fc-fusion proteins
|
|
EP3468991A1
(en)
|
2016-11-21 |
2019-04-17 |
cureab GmbH |
Anti-gp73 antibodies and immunoconjugates
|
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Ｍｅｔ抗體以及其免疫結合物及用途
|
|
EP3568468A4
(en)
|
2017-01-12 |
2020-12-30 |
Eureka Therapeutics, Inc. |
RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES
|
|
EP3601343B1
(en)
|
2017-03-30 |
2022-05-04 |
ECS-Progastrin SA |
Compositions and methods for detecting and treating prostate cancer using progastrin binding molecule
|
|
CA3058270C
(en)
|
2017-03-30 |
2023-07-18 |
Ecs-Progastrin Sa |
Compositions and methods for detecting lung cancer
|
|
BR112019018051A2
(pt)
|
2017-04-12 |
2020-04-07 |
Hoffmann La Roche |
método para produzir um composto, composto e substância
|
|
EP3612567B1
(en)
|
2017-04-19 |
2024-09-11 |
Bluefin Biomedicine, Inc. |
Anti-vtcn1 antibodies and antibody drug conjugates
|
|
SG11201909728XA
(en)
|
2017-04-26 |
2019-11-28 |
Eureka Therapeutics Inc |
Constructs specifically recognizing glypican 3 and uses thereof
|
|
AR111963A1
(es)
|
2017-05-26 |
2019-09-04 |
Univ California |
Método y moléculas
|
|
JP2020529832A
(ja)
|
2017-06-30 |
2020-10-15 |
ゼンコア インコーポレイテッド |
ＩＬ−１５／ＩＬ−１５Ｒαおよび抗原結合ドメインを含む標的化ヘテロダイマーＦｃ融合タンパク質
|
|
KR20200067193A
(ko)
|
2017-10-20 |
2020-06-11 |
에프. 호프만-라 로슈 아게 |
항체에 대한 카피 보호
|
|
MX2020004100A
(es)
|
2017-10-30 |
2020-07-24 |
Hoffmann La Roche |
Metodo para generacion in vivo de anticuerpos multiespecificos a partir de anticuerpos monoespecificos.
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
KR20200085828A
(ko)
|
2017-11-08 |
2020-07-15 |
젠코어 인코포레이티드 |
신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체
|
|
US11401345B2
(en)
|
2017-11-27 |
2022-08-02 |
Purdue Pharma L.P. |
Humanized antibodies targeting human tissue factor
|
|
PL3720879T3
(pl)
|
2017-12-05 |
2022-09-12 |
Progastrine Et Cancers S.À R.L. |
Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu
|
|
SG11202005732XA
(en)
|
2017-12-19 |
2020-07-29 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
|
KR20200139219A
(ko)
|
2018-04-02 |
2020-12-11 |
브리스톨-마이어스 스큅 컴퍼니 |
항-trem-1 항체 및 이의 용도
|
|
CA3096052A1
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
US11524991B2
(en)
|
2018-04-18 |
2022-12-13 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
CN112437777A
(zh)
|
2018-04-18 |
2021-03-02 |
Xencor股份有限公司 |
包含IL-15/IL-15RA Fc融合蛋白和TIM-3抗原结合结构域的靶向TIM-3的异源二聚体融合蛋白
|
|
SG11202012342WA
(en)
|
2018-06-18 |
2021-01-28 |
Eureka Therapeutics Inc |
Constructs targeting prostate-specific membrane antigen (psma) and uses thereof
|
|
BR112020026724A2
(pt)
|
2018-07-02 |
2021-03-30 |
Amgen Inc. |
Proteína de ligação ao antígeno anti-steap1
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
SG11202103192RA
(en)
|
2018-10-03 |
2021-04-29 |
Xencor Inc |
Il-12 heterodimeric fc-fusion proteins
|
|
BR112021010908A2
(pt)
|
2018-12-06 |
2021-08-31 |
Genentech, Inc. |
Método para tratamento de linfoma difuso de grandes células b, kit e imunoconjugado
|
|
CN114173875A
(zh)
|
2019-03-01 |
2022-03-11 |
Xencor股份有限公司 |
结合enpp3和cd3的异二聚抗体
|
|
CN113874392A
(zh)
|
2019-03-28 |
2021-12-31 |
丹尼斯科美国公司 |
工程化抗体
|
|
MX2021013825A
(es)
|
2019-05-14 |
2022-01-18 |
Genentech Inc |
Procedimientos de uso de inmunoconjugados anti-cd79b para tratar el linfoma folicular.
|
|
CN114173822A
(zh)
|
2019-06-03 |
2022-03-11 |
芝加哥大学 |
用胶原结合药物载体治疗癌症的方法和组合物
|
|
MX2021014931A
(es)
|
2019-06-07 |
2022-01-24 |
Amgen Inc |
Construcciones de union biespecificas con enlazadores selectivamente escindibles.
|
|
JPWO2021010326A1
(es)
|
2019-07-12 |
2021-01-21 |
|
|
|
KR20220041915A
(ko)
|
2019-08-06 |
2022-04-01 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
바이오제약 조성물 및 관련 방법
|
|
US20230165967A1
(en)
|
2019-10-04 |
2023-06-01 |
TAE Life Sciences |
Antibody Compositions Comprising Fc Mutations and Site-Specific Conjugation Properties for use in Treating Cancer, Immunological Disorders, and Methods Thereof
|
|
CA3153880A1
(en)
|
2019-10-18 |
2020-06-09 |
Juana Elva HERNANDEZ MONTALVO |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
WO2021202473A2
(en)
|
2020-03-30 |
2021-10-07 |
Danisco Us Inc |
Engineered antibodies
|
|
WO2021217051A1
(en)
|
2020-04-24 |
2021-10-28 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
CA3184351A1
(en)
|
2020-06-04 |
2021-12-09 |
Amgen Inc. |
Bispecific binding constructs
|
|
CA3183808A1
(en)
|
2020-06-11 |
2021-12-16 |
Genentech, Inc. |
Nanolipoprotein-polypeptide conjugates and compositions, systems, and methods using same
|
|
KR102607909B1
(ko)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
항-cd28 조성물
|
|
EP4255931A1
(en)
|
2020-12-03 |
2023-10-11 |
Amgen Inc. |
Immunoglobuline constructs with multiple binding domains
|
|
WO2022147463A2
(en)
|
2020-12-31 |
2022-07-07 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
|
AU2022232375A1
(en)
|
2021-03-09 |
2023-09-21 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
|
MX2023013264A
(es)
|
2021-05-12 |
2023-11-30 |
Genentech Inc |
Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes.
|
|
EP4347656A1
(en)
|
2021-05-28 |
2024-04-10 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapies for treating cancer
|
|
JP2024530643A
(ja)
|
2021-08-03 |
2024-08-23 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
バイオ医薬組成物および安定同位体標識ペプチドマッピング法
|
|
US11807685B2
(en)
|
2021-08-05 |
2023-11-07 |
The Uab Research Foundation |
Anti-CD47 antibody and uses thereof
|
|
KR20240046524A
(ko)
|
2021-08-07 |
2024-04-09 |
제넨테크, 인크. |
미만성 거대 b-세포 림프종을 치료하기 위해 항-cd79b 면역접합체를 사용하는 방법
|
|
EP4412713A1
(en)
|
2021-10-05 |
2024-08-14 |
GlaxoSmithKline Intellectual Property Development Ltd |
Combination therapies for treating cancer
|
|
WO2024015953A1
(en)
|
2022-07-15 |
2024-01-18 |
Danisco Us Inc. |
Methods for producing monoclonal antibodies
|
|
WO2024121711A1
(en)
|
2022-12-05 |
2024-06-13 |
Glaxosmithkline Intellectual Property Development Limited |
Methods of treatment using b-cell maturation antigen antagonists
|
