PL3720879T3 - Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu - Google Patents

Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu

Info

Publication number
PL3720879T3
PL3720879T3 PL18829742.8T PL18829742T PL3720879T3 PL 3720879 T3 PL3720879 T3 PL 3720879T3 PL 18829742 T PL18829742 T PL 18829742T PL 3720879 T3 PL3720879 T3 PL 3720879T3
Authority
PL
Poland
Prior art keywords
immunotherapy
combination therapy
treat cancer
progastrin antibody
progastrin
Prior art date
Application number
PL18829742.8T
Other languages
English (en)
Inventor
Alexandre PRIEUR
Original Assignee
Progastrine Et Cancers S.À R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progastrine Et Cancers S.À R.L. filed Critical Progastrine Et Cancers S.À R.L.
Publication of PL3720879T3 publication Critical patent/PL3720879T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
PL18829742.8T 2017-12-05 2018-12-05 Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu PL3720879T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762594755P 2017-12-05 2017-12-05
PCT/EP2018/083651 WO2019110662A1 (en) 2017-12-05 2018-12-05 Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer

Publications (1)

Publication Number Publication Date
PL3720879T3 true PL3720879T3 (pl) 2022-09-12

Family

ID=64949216

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18829742.8T PL3720879T3 (pl) 2017-12-05 2018-12-05 Terapia skojarzona przeciwciałami przeciwko progastynie i immunoterapią w leczeniu nowotworu

Country Status (14)

Country Link
US (2) US11046758B2 (pl)
EP (1) EP3720879B1 (pl)
JP (1) JP7104153B2 (pl)
KR (1) KR102461238B1 (pl)
CN (1) CN111670197A (pl)
AU (1) AU2018379320B2 (pl)
CA (1) CA3084687C (pl)
DK (1) DK3720879T3 (pl)
ES (1) ES2920283T3 (pl)
PL (1) PL3720879T3 (pl)
PT (1) PT3720879T (pl)
SG (1) SG11202005296SA (pl)
TW (1) TWI763956B (pl)
WO (1) WO2019110662A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3720879T3 (da) * 2017-12-05 2022-06-20 Progastrine Et Cancers S A R L Kombinationsterapi mellem anti-progastrin-antistof og immunterapi til behandling af cancer
EP3759492A1 (en) * 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
CN111171146B (zh) * 2020-02-20 2022-03-04 西北农林科技大学 抗h9n2亚型禽流感病毒的纳米抗体、制备方法和应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4716111A (en) 1982-08-11 1987-12-29 Trustees Of Boston University Process for producing human antibodies
US4975278A (en) 1988-02-26 1990-12-04 Bristol-Myers Company Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
GB8924581D0 (en) 1989-11-01 1989-12-20 Pa Consulting Services Bleaching of hair
WO1991010741A1 (en) 1990-01-12 1991-07-25 Cell Genesys, Inc. Generation of xenogeneic antibodies
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5546806A (en) 1991-10-17 1996-08-20 Kain; Aron Z. Microwave vector displacement and acceleration transducer
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
ZA932522B (en) 1992-04-10 1993-12-20 Res Dev Foundation Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
US5792632A (en) 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5474896A (en) 1992-05-05 1995-12-12 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
EP0752248B1 (en) 1992-11-13 2000-09-27 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0823941A4 (en) 1995-04-28 2001-09-19 Abgenix Inc HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
US5830729A (en) 1996-04-18 1998-11-03 Institut Pasteur I Sce I-induced gene replacement and gene conversion in embryonic stem cells
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
CN100387621C (zh) 1997-04-14 2008-05-14 麦可麦脱股份公司 抗人抗原受体的新的生产方法及其用途
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
DE60236182D1 (de) 2001-09-14 2010-06-10 Cellectis Zufällige integration von polynukleotide nach in vivo linearisierung
EP1391213A1 (en) 2002-08-21 2004-02-25 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
US20060206949A1 (en) 2003-01-28 2006-09-14 Sylvain Arnould Custom-made meganuclease and use thereof
WO2006032980A1 (en) 2004-09-22 2006-03-30 Receptor Biologix, Inc. Monoclonal antibolies to progastrin
EP2597155B1 (en) 2007-10-25 2016-11-23 Sangamo BioSciences, Inc. Methods and compositions for targeted integration
LT2488551T (lt) * 2009-10-16 2018-10-25 Progastrine Et Cancers S.A R.L. Monokloniniai antikūnai prieš progastriną ir jų panaudojimas
US9217032B2 (en) 2010-01-08 2015-12-22 Les Laboratoires Servier Methods for treating colorectal cancer
US8900588B2 (en) 2010-01-08 2014-12-02 Les Laboratories Servier Methods for treating breast cancer
JP5829672B2 (ja) 2010-03-24 2015-12-09 レ ラボラトワール セルヴィエ 結腸直腸及び胃腸癌の予防
KR101576174B1 (ko) 2010-07-26 2015-12-09 르 라보레또레 쎄르비에르 간암 요법을 위한 방법 및 조성물
JOP20200094A1 (ar) * 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
SG11201702723VA (en) 2014-10-29 2017-05-30 Five Prime Therapeutics Inc Combination therapy for cancer
EA037027B1 (ru) * 2015-12-31 2021-01-27 Прогастрин Э Кансер С.А Р.Л. Применение и способ для профилактики или лечения рака желудка с использованием композиции, содержащей моноклональное прогастринсвязывающее антитело
CA3193481A1 (en) * 2015-12-31 2017-07-06 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating esophageal cancer
EP3397964B1 (en) * 2015-12-31 2021-09-29 Progastrine et Cancers S.à r.l. Compositions and methods for detecting and treating ovarian cancer
KR102616819B1 (ko) * 2017-03-30 2023-12-21 프로가스트린 에 캔서스 에스.에이 알.엘. 폐암을 치료하기 위한 조성물 및 방법
SG11201908997UA (en) * 2017-03-30 2019-10-30 Ecs Progastrin Sa Compositions and methods for detecting prostate cancer
US11583576B2 (en) * 2017-06-15 2023-02-21 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
DK3720879T3 (da) * 2017-12-05 2022-06-20 Progastrine Et Cancers S A R L Kombinationsterapi mellem anti-progastrin-antistof og immunterapi til behandling af cancer
EP3759492A1 (en) * 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy

Also Published As

Publication number Publication date
ES2920283T3 (es) 2022-08-02
CA3084687A1 (en) 2019-06-13
EP3720879B1 (en) 2022-05-11
AU2018379320B2 (en) 2023-06-15
EP3720879A1 (en) 2020-10-14
US20210009680A1 (en) 2021-01-14
PT3720879T (pt) 2022-07-13
TW201927805A (zh) 2019-07-16
TWI763956B (zh) 2022-05-11
AU2018379320A1 (en) 2020-07-02
RU2020121176A (ru) 2022-01-10
CA3084687C (en) 2024-01-02
RU2020121176A3 (pl) 2022-04-27
SG11202005296SA (en) 2020-07-29
US20210324069A1 (en) 2021-10-21
CN111670197A (zh) 2020-09-15
US11046758B2 (en) 2021-06-29
KR102461238B1 (ko) 2022-11-01
KR20200118409A (ko) 2020-10-15
JP2021505576A (ja) 2021-02-18
DK3720879T3 (da) 2022-06-20
WO2019110662A1 (en) 2019-06-13
JP7104153B2 (ja) 2022-07-20

Similar Documents

Publication Publication Date Title
IL267803A (en) Methods for treating cancer with anti-tim-3 antibodies
IL262562A (en) Combination of anti-pd-1 antibodies and radiation for cancer therapy
IL268138A (en) Combinations of cabozantinib and atezolizumab for cancer treatment
IL247066A0 (en) Cancer immunotherapy by combining local and systemic immune stimulation
HK1247630A1 (zh) 用於增强癌症治療的效果的組合物和方法
GEP20217317B (en) Combination therapy for the treatment of cancer
IL273196A (en) Claudin 6 antibodies and methods of cancer treatment
HRP20190888T8 (hr) Konjugat antitijela za igf-1r i lijeka i njegova upotreba u liječenju karcinoma
IL248704A0 (en) Combined treatment with immunotherapy and radiotherapy for the treatment of cancers that express her-2
IL275517A (en) Combined methods and treatment of cancer
SG11202005296SA (en) Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
SG11201707949XA (en) Anti-vegfr2 human antibody for anti-angiogenic and targeted cancer therapy
IL275913A (en) Methods and combined treatment for cancer treatment
IL269121A (en) Usl-311 for use in the treatment of cancer
FI3630112T3 (fi) Regorafenibin ja nivolumabin yhdistelmä syövän hoidossa
IL274866A (en) Preparations and methods for the treatment of cancer
GB201717004D0 (en) Methods of cancer therapy
GB201711769D0 (en) Methods of cancer therapy
GB201416605D0 (en) Combination therapy to reduce the risk of and to treat cancer