PL220952B1 - 2-(Pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-ony - Google Patents
2-(Pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-onyInfo
- Publication number
- PL220952B1 PL220952B1 PL391191A PL39119103A PL220952B1 PL 220952 B1 PL220952 B1 PL 220952B1 PL 391191 A PL391191 A PL 391191A PL 39119103 A PL39119103 A PL 39119103A PL 220952 B1 PL220952 B1 PL 220952B1
- Authority
- PL
- Poland
- Prior art keywords
- pyrimidin
- cyclopentyl
- methyl
- ylamino
- pyrido
- Prior art date
Links
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- 125000000623 heterocyclic group Chemical group 0.000 claims description 6
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- 125000001424 substituent group Chemical group 0.000 claims description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims description 2
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- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims description 2
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Classifications
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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Applications Claiming Priority (1)
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| US35087702P | 2002-01-22 | 2002-01-22 |
Publications (2)
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| PL391191A1 PL391191A1 (OSRAM) | 2005-07-11 |
| PL220952B1 true PL220952B1 (pl) | 2016-01-29 |
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| PL372046A PL218692B1 (pl) | 2002-01-22 | 2003-01-10 | Podstawiony 2-(pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-on oraz jego zastosowanie do leczenia zaburzenia lub stanu spowodowanego nieprawidłową proliferacją komórek |
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| PL372046A PL218692B1 (pl) | 2002-01-22 | 2003-01-10 | Podstawiony 2-(pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-on oraz jego zastosowanie do leczenia zaburzenia lub stanu spowodowanego nieprawidłową proliferacją komórek |
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| US7053070B2 (en) * | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| PT1417207E (pt) * | 2000-08-04 | 2005-11-30 | Warner Lambert Co | Processo para a preparacao de 2-(4-piridil)amino-6-dialquiloxifenil-pirido(2,3-d)pirimidin-7-onas |
| JP2004505974A (ja) * | 2000-08-04 | 2004-02-26 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | ２−（４−ピリジル）アミノ−６−ジアルキルオキシフェニルピリド〔２，３−ｄ〕ピリミジン−７−オン類の製造方法 |
| CN100376571C (zh) * | 2001-02-12 | 2008-03-26 | 霍夫曼-拉罗奇有限公司 | 6-取代的吡啶并嘧啶类化合物 |
| AU2002233706C1 (en) | 2001-02-26 | 2005-12-22 | Tanabe Seiyaku Co., Ltd. | Pyridopyrimidine or naphthyridine derivative |
| WO2003000270A1 (en) * | 2001-06-21 | 2003-01-03 | Ariad Pharmaceuticals, Inc. | Novel pyridopyrimidones and uses thereof |
| US20050154046A1 (en) * | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
| KR20060111716A (ko) | 2002-01-22 | 2006-10-27 | 워너-램버트 캄파니 엘엘씨 | 2-(피리딘-2-일아미노)-피리도[2,3-ｄ]피리미딘-7-온 |
| BR0313297A (pt) * | 2002-08-06 | 2005-06-21 | Hoffmann La Roche | 6-alcóxi-pirido-pirimidinas como inibidores de p-38 map cinase |
| US7112676B2 (en) | 2002-11-04 | 2006-09-26 | Hoffmann-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
| AU2003288994A1 (en) | 2002-12-10 | 2004-06-30 | Ono Pharmaceutical Co., Ltd. | Nitrogen-containing heterocyclic compounds and medicinal use thereof |
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| RU2317296C2 (ru) * | 2003-07-11 | 2008-02-20 | Уорнер-Ламберт Компани Ллс | Изетионатная соль селективного ингибитора cdk4 |
| PL1651612T3 (pl) | 2003-07-22 | 2012-09-28 | Astex Therapeutics Ltd | Związki 3,4-pochodne 1h-pirazolu i ich zastosowanie jako kinazy zależne od cyklin (cdk) i modulatory kinazy syntazy glikogenu-3 (gsk-3) |
| ES2386354T3 (es) * | 2003-07-29 | 2012-08-17 | Xenon Pharmaceuticals Inc. | Derivados de piridilo y su uso como agentes terapéuticos |
| PT1685131E (pt) * | 2003-11-13 | 2007-05-31 | Hoffmann La Roche | ''pirido-7-pirimidin-7-onas substituídas com hidroxialquino'' |
| US20050171182A1 (en) * | 2003-12-11 | 2005-08-04 | Roger Briesewitz | Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases |
| JP4989233B2 (ja) * | 2004-02-14 | 2012-08-01 | アイアールエム・リミテッド・ライアビリティ・カンパニー | タンパク質キナーゼ阻害剤としての化合物および組成物 |
| EP1718645A1 (en) * | 2004-02-18 | 2006-11-08 | Warner-Lambert Company LLC | 2-(pyridin-3-ylamino)-pyrido 2,3-d pyrimidin-7-ones |
| EP1740184A1 (en) * | 2004-03-30 | 2007-01-10 | Pfizer Products Incorporated | Combinations of signal transduction inhibitors |
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| RS50569B (sr) * | 2004-06-11 | 2010-05-07 | Japan Tobacco Inc. | Derivati 5-amino-2,4,7-triokso-3,4,7,8-tetrahidro-2h-pirido (2,3-d)pirimidina i slična jedinjenja za lečenje raka |
| WO2006053043A2 (en) | 2004-11-10 | 2006-05-18 | Genzyme Corporation | Methods of treating diabetes mellitus |
| US20060142312A1 (en) * | 2004-12-23 | 2006-06-29 | Pfizer Inc | C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones |
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| AR054425A1 (es) | 2005-01-21 | 2007-06-27 | Astex Therapeutics Ltd | Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico. |
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| US8404718B2 (en) | 2005-01-21 | 2013-03-26 | Astex Therapeutics Limited | Combinations of pyrazole kinase inhibitors |
| MX2007008809A (es) * | 2005-01-21 | 2007-09-07 | Astex Therapeutics Ltd | Combinaciones de inhibidores de pirazol cinasa y otros agentes antitumor. |
| US8680092B2 (en) | 2005-02-25 | 2014-03-25 | Ono Pharmaceutical Co., Ltd. | Nitrogenous heterocyclic compound and medicinal use thereof |
| AR053346A1 (es) * | 2005-03-25 | 2007-05-02 | Glaxo Group Ltd | Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38 |
| UY29439A1 (es) * | 2005-03-25 | 2006-10-02 | Glaxo Group Ltd | Nuevos compuestos |
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