KR20160009039A - “인터페론 유전자의 자극기”-의존성 신호전달을 활성화하기 위한 조성물 및 방법 - Google Patents

“인터페론 유전자의 자극기”-의존성 신호전달을 활성화하기 위한 조성물 및 방법 Download PDF

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KR20160009039A
KR20160009039A KR1020157034862A KR20157034862A KR20160009039A KR 20160009039 A KR20160009039 A KR 20160009039A KR 1020157034862 A KR1020157034862 A KR 1020157034862A KR 20157034862 A KR20157034862 A KR 20157034862A KR 20160009039 A KR20160009039 A KR 20160009039A
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substantially pure
cyclin
dinucleotide
purine
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토마스 더블유. 주니어 두벤스키
데이비드 비. 칸
메레디스 라이 링 레옹
로라 힉스 글릭만
러셀 이. 반스
에드워드 에밀 레멘스
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아두로 바이오테크, 인코포레이티드
더 리전트 오브 더 유니버시티 오브 캘리포니아
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Application filed by 아두로 바이오테크, 인코포레이티드, 더 리전트 오브 더 유니버시티 오브 캘리포니아 filed Critical 아두로 바이오테크, 인코포레이티드
Publication of KR20160009039A publication Critical patent/KR20160009039A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants

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  • Life Sciences & Earth Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
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  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
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KR1020157034862A 2013-05-18 2014-05-18 “인터페론 유전자의 자극기”-의존성 신호전달을 활성화하기 위한 조성물 및 방법 Abandoned KR20160009039A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361825005P 2013-05-18 2013-05-18
US61/825,005 2013-05-18
US201361902125P 2013-11-08 2013-11-08
US61/902,125 2013-11-08
PCT/US2014/038525 WO2014189805A1 (en) 2013-05-18 2014-05-18 Compositions and methods for activating "stimulator of interferon gene"-dependent signalling

Publications (1)

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KR20160009039A true KR20160009039A (ko) 2016-01-25

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KR1020157034862A Abandoned KR20160009039A (ko) 2013-05-18 2014-05-18 “인터페론 유전자의 자극기”-의존성 신호전달을 활성화하기 위한 조성물 및 방법

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US (3) US9724408B2 (https=)
EP (2) EP3653637A1 (https=)
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KR (1) KR20160009039A (https=)
CN (1) CN105228450B (https=)
AP (1) AP2015008700A0 (https=)
AU (1) AU2014268836B2 (https=)
BR (1) BR112015028341A2 (https=)
CA (1) CA2904536A1 (https=)
CL (1) CL2015002522A1 (https=)
CR (1) CR20150616A (https=)
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CY (1) CY1122274T1 (https=)
DK (1) DK2996473T3 (https=)
DO (1) DOP2015000281A (https=)
EC (1) ECSP15052938A (https=)
ES (1) ES2754269T3 (https=)
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HR (1) HRP20191972T1 (https=)
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PL (1) PL2996473T3 (https=)
PT (1) PT2996473T (https=)
RS (1) RS59500B1 (https=)
SA (1) SA515370123B1 (https=)
SG (1) SG11201508273RA (https=)
SI (1) SI2996473T1 (https=)
SM (1) SMT201900635T1 (https=)
SV (1) SV2015005107A (https=)
WO (1) WO2014189805A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
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KR20190113768A (ko) * 2016-12-01 2019-10-08 다케다 야쿠힌 고교 가부시키가이샤 Sting(인터페론 유전자의 자극제) 작용제로서의 환식 다이뉴클레오타이드
KR20200032180A (ko) * 2017-07-28 2020-03-25 브리스톨-마이어스 스큅 컴퍼니 항암제로서의 시클릭 디뉴클레오티드

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