DK2996473T3 - Sammensætninger og fremgangsmåder til aktivering af "stimulator af interferon-gen"-afhængig signalering - Google Patents

Sammensætninger og fremgangsmåder til aktivering af "stimulator af interferon-gen"-afhængig signalering Download PDF

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DK2996473T3
DK2996473T3 DK14800848T DK14800848T DK2996473T3 DK 2996473 T3 DK2996473 T3 DK 2996473T3 DK 14800848 T DK14800848 T DK 14800848T DK 14800848 T DK14800848 T DK 14800848T DK 2996473 T3 DK2996473 T3 DK 2996473T3
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denged
activating
compositions
methods
signal
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DK14800848T
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David B Kanne
Meredith Lai Ling Leong
Russell E Vance
Thomas W Dubensky Jr
Laura Hix Glickman
Edward Emile Lemmens
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Aduro Biotech Inc
Univ California
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
  • Saccharide Compounds (AREA)
DK14800848T 2013-05-18 2014-05-18 Sammensætninger og fremgangsmåder til aktivering af "stimulator af interferon-gen"-afhængig signalering DK2996473T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361825005P 2013-05-18 2013-05-18
US201361902125P 2013-11-08 2013-11-08
PCT/US2014/038525 WO2014189805A1 (en) 2013-05-18 2014-05-18 Compositions and methods for activating "stimulator of interferon gene"-dependent signalling

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DK2996473T3 true DK2996473T3 (da) 2019-11-04

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DK14800848T DK2996473T3 (da) 2013-05-18 2014-05-18 Sammensætninger og fremgangsmåder til aktivering af "stimulator af interferon-gen"-afhængig signalering

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US (3) US9724408B2 (da)
EP (2) EP2996473B1 (da)
JP (1) JP6453855B2 (da)
KR (1) KR20160009039A (da)
CN (1) CN105228450B (da)
AP (1) AP2015008700A0 (da)
AU (1) AU2014268836B2 (da)
BR (1) BR112015028341A2 (da)
CA (1) CA2904536A1 (da)
CL (1) CL2015002522A1 (da)
CR (1) CR20150616A (da)
CU (1) CU24377B1 (da)
CY (1) CY1122274T1 (da)
DK (1) DK2996473T3 (da)
DO (1) DOP2015000281A (da)
EC (1) ECSP15052938A (da)
ES (1) ES2754269T3 (da)
GT (1) GT201500326A (da)
HR (1) HRP20191972T1 (da)
HU (1) HUE046942T2 (da)
IL (1) IL242359B (da)
LT (1) LT2996473T (da)
ME (1) ME03586B (da)
MX (1) MX354057B (da)
MY (1) MY175308A (da)
NI (1) NI201500162A (da)
PE (1) PE20160080A1 (da)
PH (1) PH12015502438A1 (da)
PL (1) PL2996473T3 (da)
PT (1) PT2996473T (da)
RS (1) RS59500B1 (da)
SA (1) SA515370123B1 (da)
SG (1) SG11201508273RA (da)
SI (1) SI2996473T1 (da)
SM (1) SMT201900635T1 (da)
SV (1) SV2015005107A (da)
WO (1) WO2014189805A1 (da)

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