CL2015002522A1 - Composiciones y métodos para activar "estimulador de interferon gene" - señalización dependientes. - Google Patents

Composiciones y métodos para activar "estimulador de interferon gene" - señalización dependientes.

Info

Publication number
CL2015002522A1
CL2015002522A1 CL2015002522A CL2015002522A CL2015002522A1 CL 2015002522 A1 CL2015002522 A1 CL 2015002522A1 CL 2015002522 A CL2015002522 A CL 2015002522A CL 2015002522 A CL2015002522 A CL 2015002522A CL 2015002522 A1 CL2015002522 A1 CL 2015002522A1
Authority
CL
Chile
Prior art keywords
activate
compositions
methods
dependent signaling
interferon gene
Prior art date
Application number
CL2015002522A
Other languages
English (en)
Inventor
Thomas W Dubensky Jr
David B Kanne
Meredith Lai Ling Leong
Laura Hix Glickman
Russell E Vance
Edward Emile Lemmens
Original Assignee
Univ California
Aduro Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51934006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015002522(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ California, Aduro Biotech Inc filed Critical Univ California
Publication of CL2015002522A1 publication Critical patent/CL2015002522A1/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dermatology (AREA)

Abstract

COMPOSICIÓN QUE COMPRENDE UNO O MÁS DINUCLEÓTIDOS DE PURINA CÍCLICOS; USO DE LA COMPOSICIÓN PARA INDUCIR RESPUESTA INMUNE EN UN SUJETO; USO PARA INDUCIR LA PRODUCCIÓN DE INTERFERÓN DEL TIPO I QUE DEPENDE DE STING; Y USO PARA TRATAR CÁNCER.
CL2015002522A 2013-05-18 2015-09-08 Composiciones y métodos para activar "estimulador de interferon gene" - señalización dependientes. CL2015002522A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361825005P 2013-05-18 2013-05-18
US201361902125P 2013-11-08 2013-11-08

Publications (1)

Publication Number Publication Date
CL2015002522A1 true CL2015002522A1 (es) 2016-12-30

Family

ID=51934006

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015002522A CL2015002522A1 (es) 2013-05-18 2015-09-08 Composiciones y métodos para activar "estimulador de interferon gene" - señalización dependientes.

Country Status (37)

Country Link
US (3) US9724408B2 (es)
EP (2) EP3653637A1 (es)
JP (1) JP6453855B2 (es)
KR (1) KR20160009039A (es)
CN (1) CN105228450B (es)
AP (1) AP2015008700A0 (es)
AU (1) AU2014268836B2 (es)
BR (1) BR112015028341A2 (es)
CA (1) CA2904536A1 (es)
CL (1) CL2015002522A1 (es)
CR (1) CR20150616A (es)
CU (1) CU24377B1 (es)
CY (1) CY1122274T1 (es)
DK (1) DK2996473T3 (es)
DO (1) DOP2015000281A (es)
EC (1) ECSP15052938A (es)
ES (1) ES2754269T3 (es)
GT (1) GT201500326A (es)
HK (2) HK1219024A1 (es)
HR (1) HRP20191972T1 (es)
HU (1) HUE046942T2 (es)
IL (1) IL242359B (es)
LT (1) LT2996473T (es)
ME (1) ME03586B (es)
MX (1) MX354057B (es)
MY (1) MY175308A (es)
NI (1) NI201500162A (es)
PE (1) PE20160080A1 (es)
PH (1) PH12015502438B1 (es)
PL (1) PL2996473T3 (es)
PT (1) PT2996473T (es)
RS (1) RS59500B1 (es)
SA (1) SA515370123B1 (es)
SG (1) SG11201508273RA (es)
SI (1) SI2996473T1 (es)
SV (1) SV2015005107A (es)
WO (1) WO2014189805A1 (es)

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