WO2007070660A2
(en)
|
2005-12-13 |
2007-06-21 |
President And Fellows Of Harvard College |
Scaffolds for cell transplantation
|
DK2624873T3
(da)
|
2010-10-06 |
2020-03-02 |
Harvard College |
Injicerbare, pore-dannende hydrogeler til materiale-baserede celleterapier
|
ES2773895T3
(es)
|
2012-04-16 |
2020-07-15 |
Harvard College |
Composiciones de sílice mesoporosa para modular las respuestas inmunitarias
|
SG11201407875UA
(en)
|
2012-06-08 |
2014-12-30 |
Aduro Biotech |
Compostions and methods for cancer immunotherapy
|
SG11201502796RA
(en)
*
|
2012-12-13 |
2015-05-28 |
Aduro Biotech Inc |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
PE20160167A1
(es)
|
2013-04-29 |
2016-04-21 |
Sloan Kettering Inst Cancer |
Composiciones y metodos para alterar la senalizacion del segundo mensajero
|
EP2992000B1
(en)
|
2013-05-03 |
2020-07-08 |
The Regents of The University of California |
Cyclic di-nucleotide induction of type i interferon
|
US9549944B2
(en)
*
|
2013-05-18 |
2017-01-24 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
|
US9724408B2
(en)
|
2013-05-18 |
2017-08-08 |
Aduro Biotech, Inc. |
Compositions and methods for activating stimulator of interferon gene-dependent signalling
|
US10176292B2
(en)
|
2013-07-31 |
2019-01-08 |
Memorial Sloan-Kettering Cancer Center |
STING crystals and modulators
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
EP3071209A4
(en)
*
|
2013-11-19 |
2017-08-16 |
The University of Chicago |
Use of sting agonist as cancer treatment
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
CA2974651A1
(en)
|
2014-01-24 |
2015-07-30 |
Children's Hospital Of Eastern Ontario Research Institute Inc. |
Smc combination therapy for the treatment of cancer
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
EP3137105A4
(en)
|
2014-04-30 |
2017-12-27 |
President and Fellows of Harvard College |
Combination vaccine devices and methods of killing cancer cells
|
SG11201609021QA
(en)
|
2014-06-04 |
2016-11-29 |
Glaxosmithkline Ip Dev Ltd |
Cyclic di-nucleotides as modulators of sting
|
WO2016040880A1
(en)
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies of alk inhibitors
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
TN2017000129A1
(en)
|
2014-10-14 |
2018-10-19 |
Dana Farber Cancer Inst Inc |
Antibody molecules to pd-l1 and uses thereof
|
US11058758B2
(en)
*
|
2014-11-20 |
2021-07-13 |
National Institutes Of Biomedical Innovation, Health And Nutrition |
TH1-inducing adjuvant comprising combination of different nucleic acid adjuvants, and use of same
|
EP3546473A1
(en)
|
2014-12-16 |
2019-10-02 |
Kayla Therapeutics |
Cyclic [(2',5')p(3',5')p]-dinucleotides for cytokine induction
|
GB201501462D0
(en)
*
|
2015-01-29 |
2015-03-18 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
CA3012602A1
(en)
|
2015-01-30 |
2016-08-04 |
President And Fellows Of Harvard College |
Peritumoral and intratumoral materials for cancer therapy
|
WO2016130616A1
(en)
|
2015-02-11 |
2016-08-18 |
The Johns Hopkins University |
Bacteria over-expressing c-di-amp and therapeutic methods
|
CN107530415A
(zh)
|
2015-03-10 |
2018-01-02 |
艾杜罗生物科技公司 |
用于活化“干扰素基因刺激物”依赖性信号传导的组合物和方法
|
CN114099793A
(zh)
|
2015-04-10 |
2022-03-01 |
哈佛学院院长等 |
免疫细胞捕获装置及其制备和使用方法
|
SG11201707832RA
(en)
|
2015-04-22 |
2017-11-29 |
Curevac Ag |
Rna containing composition for treatment of tumor diseases
|
LT3317301T
(lt)
|
2015-07-29 |
2021-07-26 |
Novartis Ag |
Kombinuotos terapijos, apimančios antikūno molekules prieš lag-3
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
EP3328418A1
(en)
*
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
CN106692967A
(zh)
*
|
2015-08-12 |
2017-05-24 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合PD1的抗体(Nivolumab)在制备抗肿瘤药物中的应用
|
KR102271750B1
(ko)
*
|
2015-08-13 |
2021-06-30 |
머크 샤프 앤드 돔 코포레이션 |
Sting 효능제로서 시클릭 디-뉴클레오티드 화합물
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
CN106540255A
(zh)
*
|
2015-09-18 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用
|
WO2017075477A1
(en)
|
2015-10-28 |
2017-05-04 |
Aduro Biotech, Inc. |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
MX363780B
(es)
|
2015-12-03 |
2019-04-03 |
Glaxosmithkline Ip Dev Ltd |
Dinucleótidos de purina cíclica como moduladores del estimulador de los genes de interferón.
|
KR20180107102A
(ko)
|
2015-12-16 |
2018-10-01 |
그릿스톤 온콜로지, 인코포레이티드 |
신생항원 동정, 제조, 및 용도
|
US20180369268A1
(en)
*
|
2015-12-16 |
2018-12-27 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"- dependent interferon production
|
CA3007671A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
EP3402819A1
(en)
|
2016-01-11 |
2018-11-21 |
Novartis AG |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
WO2017123657A1
(en)
|
2016-01-11 |
2017-07-20 |
Gary Glick |
Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
|
WO2017123669A1
(en)
|
2016-01-11 |
2017-07-20 |
Gary Glick |
Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
|
CN106544319A
(zh)
*
|
2016-01-24 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
一种用于刺激树突状细胞成熟的组合物及其用于刺激树突状细胞成熟的方法
|
CN115531609A
(zh)
|
2016-02-06 |
2022-12-30 |
哈佛学院校长同事会 |
重塑造血巢以重建免疫
|
HRP20221263T1
(hr)
*
|
2016-03-18 |
2023-03-03 |
Immune Sensor, Llc |
Ciklički di-nukleotidni spojevi i postupci uporabe
|
CN106540256A
(zh)
*
|
2016-03-27 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸-脂质体偶联单克隆抗体在抗肿瘤中的应用
|
WO2017175156A1
(en)
|
2016-04-07 |
2017-10-12 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides useful as protein modulators
|
HRP20220936T1
(hr)
|
2016-04-07 |
2022-10-28 |
Glaxosmithkline Intellectual Property Development Limited |
Heterociklički amidi korisni kao modulatori proteina
|
CA3021349A1
(en)
|
2016-04-19 |
2017-10-26 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
US10533007B2
(en)
|
2016-04-19 |
2020-01-14 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
US10696985B1
(en)
|
2016-06-06 |
2020-06-30 |
Vanderbilt University |
Reversibly crosslinked endosomolytic polymer vesicles for cytosolic drug delivery
|
US11098077B2
(en)
|
2016-07-05 |
2021-08-24 |
Chinook Therapeutics, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
US11033569B2
(en)
*
|
2016-07-06 |
2021-06-15 |
Sperovie Biosciences, Inc. |
Compounds,Compositions, and methods for the treatment of disease
|
WO2018009652A1
(en)
*
|
2016-07-06 |
2018-01-11 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
CN115404196A
(zh)
|
2016-07-13 |
2022-11-29 |
哈佛学院院长等 |
抗原呈递细胞模拟支架及其制备和使用方法
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
US11725035B2
(en)
|
2016-08-09 |
2023-08-15 |
Stipe Therapeutics Aps |
Methods of treating a disorder associated with with insufficient stimulator of interferon genes (STING) activity
|
CN110121335A
(zh)
|
2016-08-30 |
2019-08-13 |
达纳-法伯癌症研究所股份有限公司 |
药物递送组合物及其用途
|
WO2018053508A1
(en)
|
2016-09-19 |
2018-03-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for inducing an immune response
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
SI3523287T1
(sl)
|
2016-10-04 |
2021-11-30 |
Merck Sharp & Dohme Corp. |
Benzo(b)tiofenske spojine kot agonisti STING
|
EP3523314A1
(de)
|
2016-10-07 |
2019-08-14 |
Biolog Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH |
Benzimidazolhaltige cyclische dinukleotide, verfahren zu deren herstellung und ihre verwendung zur aktivierung von stimulator von interferongenen (sting)-abhängigen signalwegen
|
US10881726B2
(en)
|
2016-10-11 |
2021-01-05 |
The Governors Of The University Of Alberta |
Hepatitis C virus immunogenic compositions and methods of use thereof
|
JOP20170188A1
(ar)
*
|
2016-11-25 |
2019-01-30 |
Janssen Biotech Inc |
ثنائي النوكليوتيدات الحلقية كمنبهات ستينغ (sting)
|
JOP20170192A1
(ar)
*
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
JP2018090562A
(ja)
*
|
2016-12-01 |
2018-06-14 |
武田薬品工業株式会社 |
環状ジヌクレオチド
|
EP3558358A4
(en)
*
|
2016-12-20 |
2020-09-30 |
Merck Sharp & Dohme Corp. |
COMBINATIONS OF PD-1 ANTAGONISTS AND CYCLIC DINUKLEOTIDE STING AGONISTS FOR CANCER TREATMENT
|
EP3558324A4
(en)
*
|
2016-12-20 |
2020-08-05 |
Merck Sharp & Dohme Corp. |
CYCLIC STING DINUCLEOTID AGONISTS FOR CANCER TREATMENT
|
WO2018138685A2
(en)
*
|
2017-01-27 |
2018-08-02 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
CN110234404A
(zh)
|
2017-01-27 |
2019-09-13 |
詹森生物科技公司 |
作为sting激动剂的环状二核苷酸
|
WO2018144775A1
(en)
|
2017-02-01 |
2018-08-09 |
Modernatx, Inc. |
Immunomodulatory therapeutic mrna compositions encoding activating oncogene mutation peptides
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
JP2018131427A
(ja)
*
|
2017-02-17 |
2018-08-23 |
国立研究開発法人理化学研究所 |
免疫細胞の制御技術
|
CA3053568A1
(en)
|
2017-02-21 |
2018-08-30 |
Board Of Regents, The University Of Texas System |
Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling
|
CN106727331B
(zh)
*
|
2017-03-13 |
2022-02-01 |
杭州星鳌生物科技有限公司 |
免疫脂质体-环二核苷酸的组成、制备方法及其在抗肿瘤中的应用
|
SG11201908530QA
(en)
|
2017-03-20 |
2019-10-30 |
Genocea Biosciences Inc |
Treatment methods
|
JOP20190218A1
(ar)
|
2017-03-22 |
2019-09-22 |
Boehringer Ingelheim Int |
مركبات ثنائية النيوكليوتيدات حلقية معدلة
|
KR20190140454A
(ko)
|
2017-04-13 |
2019-12-19 |
아두로 바이오테크 홀딩스, 유럽 비.브이. |
항-sirp 알파 항체
|
EP3610022A1
(en)
|
2017-04-14 |
2020-02-19 |
Tollnine, Inc. |
Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
AR113224A1
(es)
*
|
2017-04-28 |
2020-02-19 |
Novartis Ag |
Conjugados de anticuerpo que comprenden un agonista de sting
|
WO2018208667A1
(en)
*
|
2017-05-12 |
2018-11-15 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
WO2018210279A1
(zh)
*
|
2017-05-16 |
2018-11-22 |
科济生物医药(上海)有限公司 |
Toll样受体激动剂与免疫效应细胞的联用
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
ANTIBODY MOLECULES DIRECTED AGAINST CD73 AND CORRESPONDING USES
|
EP3641812A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
EP3652166A1
(en)
|
2017-07-14 |
2020-05-20 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
EP3431484A1
(en)
*
|
2017-07-21 |
2019-01-23 |
Ludwig-Maximilians-Universität München |
A fluorescent cyclic dinucleotide and its use in methods of identifying substances having an ability to modulate the cgas/sting pathway
|
KR20200032180A
(ko)
*
|
2017-07-28 |
2020-03-25 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
CA3071538A1
(en)
|
2017-08-04 |
2019-02-07 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene sting agonists for cancer treatment
|
WO2019027857A1
(en)
|
2017-08-04 |
2019-02-07 |
Merck Sharp & Dohme Corp. |
COMBINATIONS OF PD-1 ANTAGONISTS AND STING BENZO [B] THIOPHENIC AGONISTS FOR THE TREATMENT OF CANCER
|
TWI808092B
(zh)
|
2017-08-30 |
2023-07-11 |
中國大陸商北京軒義醫藥科技有限公司 |
作為干擾素基因調節劑之刺激劑的環狀二核苷酸
|
JP7208225B2
(ja)
*
|
2017-08-31 |
2023-01-18 |
ブリストル-マイヤーズ スクイブ カンパニー |
抗癌剤としての環状ジヌクレオチド
|
EP3675859A4
(en)
|
2017-08-31 |
2021-06-30 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND PROCEDURES FOR TREATMENT OF DISEASES
|
KR102651946B1
(ko)
*
|
2017-08-31 |
2024-03-26 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
EP3678668B1
(en)
|
2017-09-08 |
2024-01-10 |
The Board of Trustees of the Leland Stanford Junior University |
Enpp1 inhibitors and their use for the treatment of cancer
|
US11707531B2
(en)
|
2017-09-11 |
2023-07-25 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
US11584774B2
(en)
|
2017-09-11 |
2023-02-21 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
EP3692033A1
(en)
|
2017-10-05 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (sting) useful in treating hiv
|
CN111417630B
(zh)
|
2017-10-05 |
2023-06-06 |
葛兰素史克知识产权开发有限公司 |
干扰素基因刺激因子(sting)的调节剂
|
CA3078744A1
(en)
|
2017-10-10 |
2019-04-18 |
Gritstone Oncology, Inc. |
Neoantigen identification using hotspots
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
PE20210156A1
(es)
|
2017-11-10 |
2021-01-26 |
Takeda Pharmaceuticals Co |
Compuestos moduladores de sting y metodos de elaboracion y uso
|
EA038805B1
(ru)
*
|
2017-11-21 |
2021-10-21 |
Такеда Фармасьютикал Компани Лимитед |
Циклические динуклеотиды в качестве агонистов sting (стимулятор генов интерферона)
|
CN111630602A
(zh)
|
2017-11-22 |
2020-09-04 |
磨石肿瘤生物技术公司 |
减少新抗原的接合表位呈递
|
US11633473B2
(en)
|
2017-11-27 |
2023-04-25 |
Children's Medical Center Corporation |
Stimulator of Interferon Genes (STING) ligands and uses thereof
|
WO2019123339A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
EP3727401A4
(en)
|
2017-12-20 |
2022-04-06 |
Merck Sharp & Dohme Corp. |
CYCLIC DINUCLEOTIDE COMPOUNDS USED AS STING AGONISTS
|
CN111566120B
(zh)
|
2017-12-20 |
2023-09-29 |
捷克共和国有机化学与生物化学研究所 |
活化sting转接蛋白的具有膦酸酯键的3’3’环状二核苷酸
|
TWI818943B
(zh)
*
|
2018-01-04 |
2023-10-21 |
中央研究院 |
用於增加療效之可與細胞結合的免疫佐劑
|
WO2019147509A1
(en)
*
|
2018-01-26 |
2019-08-01 |
The Regents Of The University Of California |
Intranasal delivery of a cyclic-di-nucleotide adjuvanted vaccine for tuberculosis
|
AU2019213843A1
(en)
|
2018-02-02 |
2020-08-20 |
Aduro Biotech Inc. |
Combination of STING agonist and IL-15/IL15-Ra for the treatment of cancer
|
WO2019154844A1
(en)
*
|
2018-02-06 |
2019-08-15 |
Aarhus Universitet |
Modulation of p62 and sting activity
|
TW202003023A
(zh)
|
2018-03-12 |
2020-01-16 |
美商詹森藥物公司 |
針對尿路感染之疫苗
|
CN110272462B
(zh)
*
|
2018-03-15 |
2023-03-10 |
南开大学 |
制备化合物的方法
|
TW202003032A
(zh)
|
2018-03-23 |
2020-01-16 |
美商科迪亞克生物科學公司 |
包含s t i n g 促效劑之胞外囊泡
|
CN111989338A
(zh)
|
2018-03-27 |
2020-11-24 |
勃林格殷格翰国际有限公司 |
修饰的环二核苷酸化合物
|
EP3774834A1
(en)
|
2018-03-27 |
2021-02-17 |
Boehringer Ingelheim International GmbH |
Cyclic dinucleotide compounds containing 2-aza-hypoxanthine or 6h-pytazolo[1,5-d][1,2,4]triazin-7-one as sting agonists
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
EP3774764A1
(en)
|
2018-04-03 |
2021-02-17 |
Merck Sharp&Dohme Corp. |
Benzothiophenes and related compounds as sting agonists
|
WO2019195658A1
(en)
|
2018-04-05 |
2019-10-10 |
Dana-Farber Cancer Institute, Inc. |
Sting levels as a biomarker for cancer immunotherapy
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
JP7296398B2
(ja)
|
2018-04-06 |
2023-06-22 |
インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール,ヴイ.ヴイ.アイ. |
3’3’-環状ジヌクレオチド
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
CN112074516A
(zh)
|
2018-04-25 |
2020-12-11 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
CN108310378A
(zh)
*
|
2018-04-28 |
2018-07-24 |
杭州星鳌生物科技有限公司 |
一类新型免疫联体抗肿瘤创新药物的制备及其应用
|
TW202014193A
(zh)
|
2018-05-03 |
2020-04-16 |
捷克科學院有機化學與生物化學研究所 |
包含碳環核苷酸之2’3’-環二核苷酸
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
US20210205348A1
(en)
|
2018-06-01 |
2021-07-08 |
Eisai R&D Management Co., Ltd. |
Methods for the Treatment of Bladder Cancer
|
CN112672748A
(zh)
*
|
2018-06-20 |
2021-04-16 |
耶鲁大学 |
Rig-i激动剂以及使用其的治疗
|
CN112823151A
(zh)
|
2018-07-03 |
2021-05-18 |
艾福姆德尤股份有限公司 |
用于治疗与sting活性有关的疾病的化合物和组合物
|
MA53095A
(fr)
|
2018-07-03 |
2021-05-12 |
Ifm Due Inc |
Composés et compositions pour traiter des états pathologiques associés à une activité de sting
|
EP3820992A2
(en)
*
|
2018-07-11 |
2021-05-19 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
MX2021001581A
(es)
|
2018-08-16 |
2021-04-19 |
Innate Tumor Immunity Inc |
Compuestos de 4-amino-1h-imidazo[4,5-c]quinolina sustituidos y metodos mejorados para su preparacion.
|
CA3099904A1
(en)
|
2018-08-16 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Salts of compounds and crystals thereof
|
KR20210046023A
(ko)
|
2018-08-16 |
2021-04-27 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
이미다조[4,5-c]퀴놀린 유래 NLRP3-조정제
|
EP3837015B1
(en)
|
2018-08-16 |
2024-02-14 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
EP3848054A4
(en)
|
2018-09-06 |
2022-06-01 |
Daiichi Sankyo Company, Limited |
NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF
|
WO2020049534A1
(en)
|
2018-09-07 |
2020-03-12 |
Novartis Ag |
Sting agonist and combination therapy thereof for the treatment of cancer
|
JP2021535930A
(ja)
*
|
2018-09-17 |
2021-12-23 |
キュラティス インコーポレイティッド |
Stingアゴニストを含む抗原性補強剤及びワクチン組成物
|
JP7218431B2
(ja)
|
2018-09-21 |
2023-02-06 |
シャンハイ ドーァ ノボ ファーマテック カンパニー,リミティド |
環状ジヌクレオチド類似体、その医薬組成物及び使用
|
US11110106B2
(en)
|
2018-10-29 |
2021-09-07 |
Venenum Biodesign, LLC |
Sting agonists for treating bladder cancer and solid tumors
|
US11161864B2
(en)
|
2018-10-29 |
2021-11-02 |
Venenum Biodesign, LLC |
Sting agonists
|
WO2020092379A1
(en)
|
2018-10-29 |
2020-05-07 |
Genocea Biosciences, Inc. |
Treatment methods
|
WO2020092633A1
(en)
|
2018-10-30 |
2020-05-07 |
Vanderbilt University |
Graft copolymers, methods of forming graft copolymers, and methods of use thereof
|
JP2022509929A
(ja)
|
2018-10-31 |
2022-01-25 |
ノバルティス アーゲー |
Stingアゴニストを含むdc-sign抗体コンジュゲート
|
US11596692B1
(en)
|
2018-11-21 |
2023-03-07 |
Incyte Corporation |
PD-L1/STING conjugates and methods of use
|
US20220033431A1
(en)
*
|
2018-12-07 |
2022-02-03 |
Merck Sharp & Dohme Corp. |
Cyclic Di-Nucleotide Compounds as STING Agonists
|
EP3891165A4
(en)
*
|
2018-12-07 |
2022-08-24 |
Merck Sharp & Dohme Corp. |
CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS
|
EP3891166A4
(en)
*
|
2018-12-07 |
2022-08-24 |
Merck Sharp & Dohme Corp. |
CYCLIC DI-NUCLEOTIDE COMPOUNDS USED AS STING AGONISTS
|
WO2020143740A1
(zh)
*
|
2019-01-10 |
2020-07-16 |
南开大学 |
环二核苷酸前药分子及其制备方法和应用
|
CN113286786A
(zh)
|
2019-01-14 |
2021-08-20 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
JP2022517111A
(ja)
|
2019-01-14 |
2022-03-04 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
がんの治療に用いるためのヘテロ環nlrp3モジュレーター
|
CN113286787A
(zh)
|
2019-01-14 |
2021-08-20 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
EP3911416A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
WO2020150417A2
(en)
|
2019-01-17 |
2020-07-23 |
Ifm Due, Inc. |
Compounds and compositions for treating conditions associated with sting activity
|
US10998091B2
(en)
|
2019-02-07 |
2021-05-04 |
Sandeep Patil |
Systems for monitoring compliance with a patch dosage regimen and methods of using the same
|
US20220143061A1
(en)
*
|
2019-03-07 |
2022-05-12 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
EP3935065A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
DK3934757T3
(da)
|
2019-03-07 |
2023-04-17 |
Inst Of Organic Chemistry And Biochemistry Ascr V V I |
2'3'-cykliske dinukleotider og prodrugs deraf
|
EA202192392A1
(ru)
|
2019-03-18 |
2022-02-09 |
Янссен Фармасьютикалз, Инк. |
Способы получения биоконъюгатов полисахаридных о-антигенов e.coli, их композиции и способы их применения
|
JP7370391B2
(ja)
|
2019-03-18 |
2023-10-27 |
ヤンセン ファーマシューティカルズ,インコーポレーテッド |
大腸菌o抗原多糖のバイオコンジュゲート、その製造方法およびその使用方法
|
WO2020191369A1
(en)
|
2019-03-21 |
2020-09-24 |
Codiak Biosciences, Inc. |
Process for preparing extracellular vesicles
|
WO2020191377A1
(en)
|
2019-03-21 |
2020-09-24 |
Codiak Biosciences, Inc. |
Extracellular vesicle conjugates and uses thereof
|
AU2020240135A1
(en)
|
2019-03-21 |
2021-10-14 |
Lonza Sales Ag |
Extracellular vesicles for vaccine delivery
|
EP3946324A4
(en)
|
2019-04-04 |
2022-11-30 |
Merck Sharp & Dohme LLC |
HISTONE DEACETYLASE-3 INHIBITORS USEFUL FOR THE TREATMENT OF CANCER, INFLAMMATION, NEURODEGENERATIVE DISEASES AND DIABETES
|
TW202104214A
(zh)
|
2019-04-05 |
2021-02-01 |
英商葛蘭素史密斯克藍智慧財產發展有限公司 |
化合物
|
EP3962493A2
(en)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
|
JP2022531899A
(ja)
|
2019-05-09 |
2022-07-12 |
アリゴス セラピューティクス インコーポレイテッド |
Stingモジュレータとしての修飾環状ジヌクレオシド化合物
|
KR20220006519A
(ko)
|
2019-05-10 |
2022-01-17 |
다케다 야쿠힌 고교 가부시키가이샤 |
항체 약물 접합체
|
MA56047A
(fr)
|
2019-05-29 |
2022-04-06 |
Ifm Due Inc |
Composés et compositions destinés au traitement d'états pathologiques associés à une activité de sting
|
US20230181758A1
(en)
|
2019-07-03 |
2023-06-15 |
Codiak Biosciences, Inc. |
Extracellular vesicles targeting dendritic cells and uses thereof
|
US20220251200A1
(en)
|
2019-07-03 |
2022-08-11 |
Codiak Biosciences, Inc. |
Extracellular vesicles targeting t cells and uses thereof
|
EP3993834A1
(en)
|
2019-07-05 |
2022-05-11 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
CA3149482A1
(en)
|
2019-08-02 |
2021-02-11 |
Mersana Therapeutics, Inc. |
Bis-[n-((5-carbamoyl)-1h-benzo[d]imidazol-2-yl)-pyrazol-5-carboxamide] derivatives and related compounds as sting (stimulator of interferon genes) agonists for the treatment of cancer
|
AU2020328507A1
(en)
|
2019-08-12 |
2022-03-17 |
Purinomia Biotech, Inc. |
Methods and compositions for promoting and potentiating T-cell mediated immune responses through ADCC targeting of CD39 expressing cells
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
EP3785719A1
(en)
*
|
2019-08-28 |
2021-03-03 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
New use of cyclic dinucleotides
|
EP4034276A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Methods of producing extracellular vesicles
|
EP4034081A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Extracellular vesicle compositions
|
KR20220094221A
(ko)
|
2019-09-25 |
2022-07-05 |
코디악 바이오사이언시즈, 인크. |
종양의 치료를 위한 il-12 디스플레잉 엑소좀과 조합된 sting 효능제 포함 엑소좀
|
WO2021062058A1
(en)
|
2019-09-25 |
2021-04-01 |
Codiak Biosciences, Inc. |
Sting agonist comprising exosomes for treating neuroimmunological disorders
|
KR20220107166A
(ko)
|
2019-10-02 |
2022-08-02 |
얀센 백신스 앤드 프리벤션 비.브이. |
스타필로코커스 펩티드 및 사용 방법
|
TW202128775A
(zh)
|
2019-10-16 |
2021-08-01 |
英商阿法克塔生命科學有限公司 |
PD-L1抑制劑-TGFβ抑制劑雙特異性藥物部分
|
US20230074558A1
(en)
|
2019-12-06 |
2023-03-09 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
KR20220127848A
(ko)
|
2020-01-10 |
2022-09-20 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Nlrp3 조정제
|
BR112022013720A2
(pt)
|
2020-01-16 |
2022-10-11 |
Janssen Pharmaceuticals Inc |
Mutante fimh, composições com o mesmo e seu uso
|
CN115427458A
(zh)
|
2020-02-28 |
2022-12-02 |
塔拉克治疗公司 |
转谷氨酰胺酶介导的缀合
|
MX2022009597A
(es)
|
2020-03-06 |
2022-09-02 |
Daiichi Sankyo Co Ltd |
Conjugado de anticuerpo-farmaco que incluye derivado de dinucleotido ciclico novedoso.
|
WO2021184017A1
(en)
|
2020-03-13 |
2021-09-16 |
Codiak Biosciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
EP4121450A2
(en)
|
2020-03-20 |
2023-01-25 |
Codiak BioSciences, Inc. |
Extracellular vesicles for therapy
|
KR20220167275A
(ko)
|
2020-04-10 |
2022-12-20 |
오노 야꾸힝 고교 가부시키가이샤 |
암 치료 방법
|
US11857618B2
(en)
|
2020-04-17 |
2024-01-02 |
Emory University |
Boosting immunogenicity of vaccines using saponins and agonists of the intracellular stimulator of interferon genes pathway
|
AU2021270750A1
(en)
|
2020-05-13 |
2022-12-08 |
Massachusetts Institute Of Technology |
Compositions of polymeric microdevices and their use in cancer immunotherapy
|
WO2021237100A1
(en)
|
2020-05-21 |
2021-11-25 |
Codiak Biosciences, Inc. |
Methods of targeting extracellular vesicles to lung
|
WO2022032191A1
(en)
|
2020-08-07 |
2022-02-10 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
WO2022050300A1
(ja)
|
2020-09-02 |
2022-03-10 |
第一三共株式会社 |
新規エンド-β-N-アセチルグルコサミニダーゼ
|
CA3190820A1
(en)
|
2020-09-17 |
2022-03-24 |
Janssen Pharmaceuticals, Inc. |
Multivalent vaccine compositions comprising specified ratios of e.coli o antigen polysaccharides and uses thereof
|
CA3192470A1
(en)
|
2020-09-23 |
2022-03-31 |
Tim SOOS |
Methods of producing extracellular vesicles
|
WO2022066928A2
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Process for preparing extracellular vesicles
|
WO2022066883A1
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising kras antigens and uses thereof
|
CA3193107A1
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Process for preparing extracellular vesicles
|
JP2023545178A
(ja)
|
2020-10-14 |
2023-10-26 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Stingアゴニストと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ
|
EP3984535A1
(en)
|
2020-10-16 |
2022-04-20 |
Albert-Ludwigs-Universität Freiburg |
Nlrp3 activators for use in the treatment of infectious diseases or cancer by activating nlrp3 inflammasome
|
AU2021363267A1
(en)
|
2020-10-20 |
2023-06-22 |
Tyligand Bioscience (Shanghai) Limited |
Multifunctional cyclic dinucleotide and use thereof
|
EP4237012A1
(en)
|
2020-10-30 |
2023-09-06 |
Avacta Life Sciences Limited |
Fap-activated serum extended half-life therapeutic conjugates
|
PE20231947A1
(es)
|
2020-11-09 |
2023-12-05 |
Takeda Pharmaceuticals Co |
Conjugados de anticuerpo y farmaco
|
WO2022133288A1
(en)
|
2020-12-17 |
2022-06-23 |
Trustees Of Tufts College |
Fap-activated radiotheranostics, and uses related thereto
|
AU2022207740A1
(en)
|
2021-01-12 |
2023-06-29 |
Janssen Pharmaceuticals, Inc. |
Fimh mutants, compositions therewith and use thereof
|
TW202241454A
(zh)
|
2021-02-01 |
2022-11-01 |
日商第一三共股份有限公司 |
抗體-免疫賦活化劑共軛物之新穎製造方法
|
KR20230164108A
(ko)
|
2021-04-01 |
2023-12-01 |
얀센 파마슈티칼즈, 인코포레이티드 |
E. coli O18 생물접합체의 생산
|
JP2024514707A
(ja)
|
2021-04-20 |
2024-04-02 |
アンスティテュ・クリー |
免疫療法における使用のための組成物及び方法
|
WO2022223622A1
(en)
|
2021-04-20 |
2022-10-27 |
Institut Curie |
Compositions and methods for use in immunotherapy
|
WO2022234003A1
(en)
|
2021-05-07 |
2022-11-10 |
Avacta Life Sciences Limited |
Cd33 binding polypeptides with stefin a protein
|
US20220313724A1
(en)
*
|
2021-05-17 |
2022-10-06 |
Highlight Therapeutics, S.L. |
Compositions for intratumoral administration and related methods
|
WO2023056468A1
(en)
|
2021-09-30 |
2023-04-06 |
Codiak Biosciences, Inc. |
Extracellular vesicle comprising cholesterol tagged sting-agonist
|
TW202334196A
(zh)
|
2021-10-07 |
2023-09-01 |
英商阿法克塔生命科學有限公司 |
Pd-l1結合多肽
|
CN114106140A
(zh)
*
|
2021-11-23 |
2022-03-01 |
哈尔滨医科大学附属肿瘤医院 |
一种表达特定sting异构体、细胞系、制备方法、用途
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
WO2023218243A1
(en)
|
2022-05-12 |
2023-11-16 |
Avacta Life Sciences Limited |
Lag-3/pd-l1 binding fusion proteins
|