BR112021018694A2 - Vesículas extracelulares para distribuição de vacina - Google Patents

Vesículas extracelulares para distribuição de vacina

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Publication number
BR112021018694A2
BR112021018694A2 BR112021018694A BR112021018694A BR112021018694A2 BR 112021018694 A2 BR112021018694 A2 BR 112021018694A2 BR 112021018694 A BR112021018694 A BR 112021018694A BR 112021018694 A BR112021018694 A BR 112021018694A BR 112021018694 A2 BR112021018694 A2 BR 112021018694A2
Authority
BR
Brazil
Prior art keywords
extracellular vesicles
exosomes
vaccine delivery
evs
methods
Prior art date
Application number
BR112021018694A
Other languages
English (en)
Inventor
Christine Mccoy
Ke Xu
Nikki Ross
J Moniz Raymond
E Mcconell Russell
J Soos Timothy
Original Assignee
Codiak Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codiak Biosciences Inc filed Critical Codiak Biosciences Inc
Publication of BR112021018694A2 publication Critical patent/BR112021018694A2/pt

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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Abstract

vesículas extracelulares para distribuição de vacina. a presente invenção refere-se a vesículas extracelulares (evs), por exemplo, exossomos, compreendendo uma carga útil (por exemplo, um antígeno, adjuvante e/ou modulador imune) e/ou uma porção de direcionamento. também são fornecidos neste documento métodos para produzir as evs (por exemplo, exossomos) e métodos para usar as evs (por exemplo, exossomos) para tratar e/ou prevenir doenças ou distúrbios, por exemplo, câncer, doença do enxerto contra hospedeiro (gvhd), doença autoimune, doenças infecciosas ou doenças fibróticas.
BR112021018694A 2019-03-21 2020-03-20 Vesículas extracelulares para distribuição de vacina BR112021018694A2 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962822008P 2019-03-21 2019-03-21
US201962835437P 2019-04-17 2019-04-17
US201962840348P 2019-04-29 2019-04-29
US201962891048P 2019-08-23 2019-08-23
US201962901166P 2019-09-16 2019-09-16
US201962946280P 2019-12-10 2019-12-10
US202062984146P 2020-03-02 2020-03-02
PCT/US2020/024023 WO2020191361A2 (en) 2019-03-21 2020-03-20 Extracellular vesicles for vaccine delivery

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BR112021018694A2 true BR112021018694A2 (pt) 2021-11-30

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US (1) US20220168415A1 (pt)
EP (1) EP3941937A2 (pt)
JP (1) JP2022526127A (pt)
KR (1) KR20220004035A (pt)
CN (1) CN114080232A (pt)
AU (1) AU2020240135A1 (pt)
BR (1) BR112021018694A2 (pt)
CA (1) CA3133311A1 (pt)
CO (1) CO2021013895A2 (pt)
IL (1) IL286556A (pt)
MX (1) MX2021011241A (pt)
SG (1) SG11202109702QA (pt)
TW (1) TW202100164A (pt)
WO (1) WO2020191361A2 (pt)

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