KR101754803B1 - 공급 체인 관리용 시스템 - Google Patents
공급 체인 관리용 시스템 Download PDFInfo
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- KR101754803B1 KR101754803B1 KR1020127013450A KR20127013450A KR101754803B1 KR 101754803 B1 KR101754803 B1 KR 101754803B1 KR 1020127013450 A KR1020127013450 A KR 1020127013450A KR 20127013450 A KR20127013450 A KR 20127013450A KR 101754803 B1 KR101754803 B1 KR 101754803B1
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- G06K17/00—Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
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Abstract
출발지부터 종착지까지 제품을 추적하기 위한 시스템이 개시된다. 시스템은 2개의 플레이트와, 전력 공급원과, 프로세서를 포함하는 프로브를 포함한다. 전력 공급원은 프로세서에 의해 제어되어 플레이트에서의 발진 출력을 생성하게 된다. 발진 전압을 이용하여, 프로브는 용량성 결합을 통해 장치에 질의한다. 장치는 제어 유닛과, 메모리 유닛과, 용량성 결합을 이용하여 통신하기 위해 상기 장치에 물리적으로 연계된 제 1 및 제 2 물질을 포함한다. 상기 장치에 연계된 정보는 상기 장치로부터, 상기 제 1 및 제 2 물질과 상기 제 1 및 제 2 플레이트 사이의 용량성 결합을 통해 상기 프로브로 전달된다.
Description
관련 출원의 상호 참조
본 출원은 2009년 11월 4일자 미국특허가출원 제61/258,182호(발명의 명칭: "Method, Device and System for Supply Chain Management of Ingestible Event Markers", 발명자: Mark Zdeblick)로부터 35 USC 119 하에 우선권을 주장하며, 그 내용은 본 발명에 포함된다.
기술분야
본 발명은 전자 장치를 이용하여 제품을 추적하기 위한 방법 및 시스템에 관한 것이다. 특히, 본 발명은 공급자로부터 소비자까지 의료 재고를 추적하기 위한 방법, 장치, 및 시스템을 포함한다.
의약 제품의 공급자들은 제품이 제작자를 떠나는 시점으로부터 제품이 최종 사용자에게 전달되는 시점까지 가품이 정품을 대체할 가능성에 대해 우려한다. 추가적으로, 분배자가 공급 체인 전체를 통해 제품을 식별할 수 있도록 패키지의 수량 및 내용을 정확하게 결정할 필요가 있다. 알려진 방법 및 시스템은 RFID와 같은 근거리장 통신을 이용한다. 이러한 알려진 방법들은 데이터 무결성, 비밀성의 결여, 등과 같은 내재적 제한사항을 갖고 있다. 따라서, 제작자로부터 최종 사용자 또는 소비자까지, 공급 체인 전체를 통해 제품의 진품 여부 및 근원(origin)을 보장하기 위해 제품에 질의(interrogation)하기 위한 시스템이 필요하다.
공급 체인 환경에서 제품 공급을 관리하기 위한 시스템이 게시된다. 다양한 형태에서, 본 발명은 다양한 제품을 프로빙(probing)하는 용량성 플레이트를 포함하여, 제품의 유효성 또는 무효성을 표시할 수 있다. 이러한 방식으로, 다양한 공급 체인이나 그외 다른 추적법이 실현될 수 있다.
제품은, 국제특허출원 PCT/US2006/016370 (공개번호: WO 2006/116718), 국제특허출원 PCT/US2007/082563 (공개번호: WO 2008/052136), 국제특허출원 PCT/US2007/024225 (공개번호: WO 2008/063626), 국제특허출원 PCT/US2007/022257 (공개번호: WO 2008/066617), 국제특허출원 PCT/US2008/052845 (공개번호: WO 2008/095183), 국제특허출원 PCT/US2008/053999 (공개번호: WO 2008/101107), 국제특허출원 PCT/US2008/056296 (공개번호: WO 2008/112577), 국제특허출원 PCT/US2008/056299 (공개번호: WO 2008/112578), 국제특허출원 PCT/US2008/077753 (공개번호: WO 2009/042812), 국제특허출원 PCT/US09/53721, 및 국제특허출원 PCT/US2007/015547 (공개번호: WO 2008/008281)과, 미국특허가출원 제61/142,849호, 제61/142,861호, 제61/177,611호, 제61/173,564호에 게시 및 설명되는 바와 같이, 예를 들어, 수액 백(IV bag), 주사기, 섭취가능한 이벤트 마커(IEM: Ingestible Event Markers), 및 유사 장치들을 포함하며, 각각의 내용은 본 발명에 포함된다. 이러한 제품은 전도성 물질/구성요소를 포함하도록 설계되는 것이 일반적이다. 용량성 결합을 이용하여 용량성 플레이트들에 의해 제품의 전도성 물질 및 구성요소들을 프로빙하면, 제품의 전도성 구성요소의 정확한 구성의 존재를 표시할 수 있다. 대안으로서, 프로빙될 때 통신 연결에 실패할 경우, 제품 불일치(예를 들어, 하나 이상의 전도성 물질이 없거나, 부정확하게 구성되었거나, 등등)를 표시할 수 있다.
도 1A는 본 발명의 일 형태에 따른 용량성 결합을 이용하여 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 1B는 본 발명의 다른 형태에 따른 용량성 결합을 이용하여 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 1C는 본 발명의 다른 형태에 따른 용량성 결합을 이용하여 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 1D는 본 발명의 또 다른 형태에 따른 용량성 결합을 이용하여 프로빙 또는 질의받을 수 있는 장치를 도시한다.
도 1E는 본 발명의 또 다른 형태에 따른 용량성 결합을 이용하여 동축 프로브/플레이트로 프로빙 또는 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 2는 본 발명의 일 형태에 따른 도 1A-1D의 장치에 대한 회로도를 도시한다.
도 2A는 도 2의 장치의 다이오드 브리지 이용을 도시한다.
도 2B는 본 발명에 따른 장치와 관련된, 플레이트 및 전도 물질을 통해 프로브와 통신하는 도 2의 장치의 로직 유닛을 도시한다.
도 2C는 본 발명의 가르침에 따른 용량성 결합을 이용하여 파워 전달 사이클 및 정보 전달 사이클에 대한 한정된 시간 주기를 도시한다.
도 3A는 본 발명에 따라 제품의 정품 여부 및 장치 작동을 확인하기 위해 관형부를 통과하는 장치를 갖는 제품을 도시한다.
도 3B는 본 발명에 따라 제품의 정품 여부를 확인하기 위해 질의 중 플레이트들 사이를 통과하는 장치의 특정 순간이다.
도 4A는 본 발명에 따른 제품과 연계된 장치의 평면도다.
도 4B는 본 발명에 따른 전도성 복합체 및 장치를 갖는 제품의 측면도다.
도 5는 본 발명에 따른 한 쌍의 프로브에 의해 질의받고 있는 장치의 측면도다.
도 1B는 본 발명의 다른 형태에 따른 용량성 결합을 이용하여 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 1C는 본 발명의 다른 형태에 따른 용량성 결합을 이용하여 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 1D는 본 발명의 또 다른 형태에 따른 용량성 결합을 이용하여 프로빙 또는 질의받을 수 있는 장치를 도시한다.
도 1E는 본 발명의 또 다른 형태에 따른 용량성 결합을 이용하여 동축 프로브/플레이트로 프로빙 또는 질의받을 수 있는 장치를 갖는 의약 제품을 도시한다.
도 2는 본 발명의 일 형태에 따른 도 1A-1D의 장치에 대한 회로도를 도시한다.
도 2A는 도 2의 장치의 다이오드 브리지 이용을 도시한다.
도 2B는 본 발명에 따른 장치와 관련된, 플레이트 및 전도 물질을 통해 프로브와 통신하는 도 2의 장치의 로직 유닛을 도시한다.
도 2C는 본 발명의 가르침에 따른 용량성 결합을 이용하여 파워 전달 사이클 및 정보 전달 사이클에 대한 한정된 시간 주기를 도시한다.
도 3A는 본 발명에 따라 제품의 정품 여부 및 장치 작동을 확인하기 위해 관형부를 통과하는 장치를 갖는 제품을 도시한다.
도 3B는 본 발명에 따라 제품의 정품 여부를 확인하기 위해 질의 중 플레이트들 사이를 통과하는 장치의 특정 순간이다.
도 4A는 본 발명에 따른 제품과 연계된 장치의 평면도다.
도 4B는 본 발명에 따른 전도성 복합체 및 장치를 갖는 제품의 측면도다.
도 5는 본 발명에 따른 한 쌍의 프로브에 의해 질의받고 있는 장치의 측면도다.
이제 도 1A를 참조하면, 완전히 포장되어 프로브를 통해 검사받은 알약 또는 정제와 같은 의약 제품(12a) 내부의 장치(10a)가 아래 설명되는 바와 같이 구성된다. 본 발명의 다양한 형태에 따르면, 장치(10a)는 본 발명의 범위 내에서 고려되는 바와 같이, 의약 제품(12a) 내에 위치하거나 의약 제품(12a)의 표면에 고정될 수 있다. 장치(10a)는 통신을 위한 제어 모듈과, 신원과 같은 정보를 저장하기 위한 메모리를 포함한다. 장치(10a)의 프로빙은, 예를 들어, 장치(10a)가 여전히 기능하고 있음을, 보장하도록 수행된다. 프로빙은 용량성 결합 방식을 이용하며, 장치(10a)의 제 1 측부 상의 제 1 금속 또는 물질(14a)에 대한 제 1 프로빙 용량성 플레이트(20a)의 구성과, 장치(10a)의 다른 측부 상의 제 2 금속 또는 물질(16a)에 대한 제 2 프로빙 용량성 플레이트(30a)의 구성에 의한 용량성 연결이 존재한다. 당 업자에게 명백하듯이, 플레이트(20a)는, 절연체가 구체적으로 도시되지는 않으나, 플레이트(30a)로부터 전기적으로 절연된다. 용량성 결합을 이용한 다양한 프로빙 방식이 예를 들어, 금속, 금속 패드, 등과 같이 실현될 수 있다. 본 발명의 일 형태에 따르면, 예를 들어, 물질(14a) 및 용량성 플레이트(20a)와 물질(16a) 및 용량성 플레이트(30a) 사이에 용량성 결합이 존재한다. 플레이트(20a, 30a)는 용량성 결합을 통해 장치(10a)와 통신할 수 있는 프로브다. 플레이트(20a, 30a)는 플레이트(20a, 30a)로부터 정보를 수신 및 정보를 처리할 수 있는 시스템(도시되지 않음)에 전기적으로 연결된다. 또한, 본 발명의 다양한 형태에 따르면, 의약 제품이 비-전도성 물질로 코팅될 수 있다.
본 발명의 다양한 형태에 따르면, 장치(10)의 일부분으로 포함되는 다양한 구성요소들이 존재한다. 예를 들어 장치(10)는, 용량성 결합 프리-인제스쳔(pre-ingestion)을 이용하여 판독할 수 있고 트랜스컨덕션 포스트-컨섬션(transconduction post-consumption)을 이용하여 통신할 수 있는 고유 신원을 갖는 섭취가능 이벤트 마커(IEM)일 수 있다. IEM의 다양한 형태가 2009년 9월 21일자 미국특허출원 제12/564,017호(발명의 명칭: "Communication System with Partial Power Source"에 개시되어 있고, 그 내용은 본 발명에 포함된다.
도 1B를 참조하면, 장치(10b)는 본 발명의 일 형태에 따른 제품(12b)의 일부분으로 도시된다. 장치(10b)는 용량성 연결을 형성하기 위해 장치(10b)의 표면 상에 증착되는 제 1 물질(14b) 및 제 2 물질(16b)을 포함한다. 물질(14b, 16b)은 장치(10b)의 제어 모듈과 통신한다. 프로브(20b, 30b)는 각각 물질(14b, 16b)에 용량성 결합된다. 따라서, 프로브(20b, 30b)가 AC 전압으로 파워-업됨에 따라, 물질(14b, 16b)이 프로브(20b, 30b)에 용량성 결합된다. 따라서, 장치(10b)의 메모리에 저장되는 장치(10b) 관련 정보는 장치(10b)의 제어 모듈에 의해 인코딩될 수 있고, 용량성 결합을 이용하여 프로브로 통신전달될 수 있다.
이제 도 1C를 참조하면, 본 발명에 따라 제품(12c)에 고정되는 장치(10c)가 도시된다. 장치(10c)는 장치(10c)의 스커트(18c)의 주변부 주위로 증착되는 제 1 물질(14c) 및 제 2 물질(16c)을 포함하며, 물질(14c, 16c) 중 적어도 일부분이 스커트(18c) 상에 증착된다. 더욱이, 물질(14c, 16c)은 장치(10c)의 제어 모듈에 연결되어, 장치(10c)의 신원을 프로브(20c, 30c)를 통해 시스템에 통신전달할 수 있다. 본 발명의 일 형태에 따르면, 물질(14c, 16c)은 섭취가능한 그래파이트 또는 탄소계 잉크 또는 페이스트와 같은 전도성 잉크다. 프로브(20c, 30c)는 AC 전원에 의해 전력을 공급받으며, 물질(14c, 16c)에 근접하여 놓일 때, 프로브(20c, 30c)는 각각 물질(14c, 16c)을 통한 용량성 결합을 통해 장치(10c)와 통신할 수 있다. 더욱이, 본 발명의 다른 형태에 따르면, 프로브(22c, 32c)는 서로 다른 위치에서 물질(14c, 16c)에 인접하여 위치하여, 장치(10c)에 대해 대안의 배치를 가능하게 하거나, 대안의 방향으로부터 장치의 프로빙을 제공할 수 있다. 프로브(20c, 30c)가 AC 전압을 공급받고 장치(10c)가 프로브(20c, 30c) 인근에 위치할 때, 물질(14c, 16c)은 용량성 결합을 통해 프로브(20c, 30c)에 연결된 시스템과 장치(10c) 사이에서 정보를 전달하는 데 사용될 수 있다.
도 1D를 이제 참조하면, 본 발명의 다른 형태에 따른 장치(10d)가 도시된다. 장치(10d)와 관련된 물질(19a)의 표면 상에 전도성 물질(14d)이 증착된다. 장치(10d)의 물질(19a) 및 물질(19b)은 서로 유사하지 않은 물질로서, 장치(10d)에 대한 부분적인 전력 공급원을 형성한다. 예를 들어, 물질(19a)은 CuCl일 수 있고, 물질(19b)은 Mg일 수 있다. 장치(10d)는 복합체(14d)를 V-high에, 또는, V-low와 동일 전위인 물질(19b)에 전기적으로 연결할 수 있는 연결부(19c)에서 트랜지스터를 또한 포함한다. 장치(10d)는, 장치(10d)와 물리적으로 연계된, 그리고 옥사이드층(17d) 상에서 지지되는 복합 물질(16d)을 포함한다. 물질(16d)은 금-도금 CuCl일 수 있다. 따라서, 발진 또는 AC 전압원으로부터 전력을 공급받는 도 1A-1C에 도시된 것과 유사한 프로브 또는 플레이트가 장치(10d)에 인접하여 놓임에 따라, 복합체(14d)와 복합체(16d) 및 프로브 사이에 용량성 결합이 존재한다. 본 발명의 일 형태에 따르면, 전압원이 분리됨에 따라, 물질(14d) 및 물질(16d)에 전달되는 에너지가 이에 따라 변하여 장치(10d) 상에 저장된다. 전압원이 0 또는 휴지 상태로 감소함에 따라, 장치(10d)는 용량성 결합을 이용하여 프로브에 대한 에너지 수신으로부터 에너지 송신으로 전환된다. 발진 에너지원을 생성하기 위해, 트랜지스터(19c)는 물질(19b)(V-low를 나타냄)과 V-high 사이에서 물질을 연결하고 분리하는데 사용된다. 물질(14d)이 V-high로부터 V-low로 에너지 레벨을 변화시킴에 따라, 정보가 프로브로 전달될 수 있다. 따라서, (도 2C에 도시되는 바와 같이) 사이클의 일부분동안 파워가 오프 또는 휴지 상태일 때, 장치(10d)는 프로브에 에너지를 전달할 수 있고, 이 에너지는 장치(10d)에 관한 정보를 포함한다. 따라서, 용량성 결합을 이용하여, 장치(10d)와 장치(10d) 인근의 프로브에 연결된 시스템 사이에서 정보가 통신전달될 수 있다.
이제 도 1E를 참조하면, 2개의 전도성 프로브/플레이트(20e 및 30e)를 갖는 동축 프로브가 절연 물질(25e)에 의해 분리된다. 내측 전도성 프로브 또는 플레이트(20e)는 절연 물질(25e)로 둘러싸이고, 절연 물질(25e)은 외측 전도성 프로브 또는 플레이트(30e)로 둘러싸인다. 장치(10e)는 의약 제품(12e)의 일부분으로 도시된다. 장치(10e)는 동축 프로브에 대향된 측부 상에 증착되는 전도성 물질 또는 잉크(15e)를 포함한다. 동축 프로브가 의약 제품(12e)에 가까이 위치함에 따라, 프로브(20e)는 장치(10e)의 중심 위에 위치하고, 프로브(30e)는 장치(10e)의 외측 변부 위에, 그리고 물질(15e)에 인접하여 위치한다. 따라서, 도 2C와 관련하여 설명되는 바와 같이, 전력 공급원이 분리되고 있기 때문에, 전력 공급원이 셧-오프 또는 휴지 상태로 바뀜에 따라 에너지가 동축 프로브로부터 장치(10e)로 전달되고, 그 후 에너지가 장치(10e)로부터, 동축 프로브에 연결된 시스템으로 전달된다.
도 2를 이제 참조하면, 전압 공급원, 예를 들어, AC 전압 또는 다른 고립 또는 교류 공급원(40)이 높은 주파수(예를 들어, 1MHz, 등)에서 구동된다. 전압 공급원은 프로브 또는 플레이트에 연결된다. 장치(10)는 제어 모듈(50)과, 물질(예를 들어, 도 1A의 물질(14, 16))이 연결되는 본딩 패드(52)를 포함한다. 본 발명의 일 형태에 따르면, 장치(10) 내부에는 내부 공급 전압을 생성하는 쇼트키 다이오드 또는 다른 타입의 다이오드와 같은, 다이오드(54)와, 장치(10)의 임피던스를 변화시키도록 온 및 오프될 수 있는 소정의 임피던스를 갖는 스위치(56)가 구성된다. 임피던스 변화는 장치(10)의 신원에 관한 정보를 전달하는데 사용된다. 임피던스 변화는 장치(10)에 관련된 정보를 인코딩할 수 있고, 커패시터(58, 60)에 의해 표시되는 바와 같은 용량성 결합을 이용하여 프로브를 통해 시스템에 전송할 수 있다. 이러한 정보는 커패시터에 의해 표현되는 프로브에 연결되는 시스템에 의해 캡처되고, R-샘플로 표시된 임피던스 간에 샘플링 증폭기를 통해 Vout으로 판독될 수 있다.
제어 모듈(50)이 플레이트를 통해 전압 공급원 근처에 놓이거나 전압 공급원에 노출되면, 용량성 결합을 통해 에너지 전달이 이루어지고, 장치(10)는 검출될 수 있는 발진 신호를 생성할 수 있다. 발진 신호는 정보를 지니고 있고, 고립 신호는, 용량성 결합의 정도에 따라 좌우될 수 있는, 1MHz 신호 또는 유사 주파수 신호(예를 들어, 500KHz)로 인코딩될 수 있다. 공급원(40)의 전압은 도 1의 용량성 플레이트 또는 프로브(20, 30)와 물질(14, 16) 간에 용량성 결합이 어느 정도 실현되는 지에 따라 결정될 것이다. 따라서, 아마도, 5V를 나타내는 높은 주파수에서, 프로브(20, 30)와 같은 프로브와, 물질 사이의 용량성 값은 커패시터(58, 60)에 의해 표현된다.
본 발명의 다른 형태에 따라, 도 2A 및 도 2B를 이제 참조하면, 장치(10)의 물질(14, 16)과 플레이트(20, 30) 사이의 상호작용의 회로도인 다이오드 브리지가 도시된다. 플레이트(20, 30)("플레이트1" 및 "플레이트2"로 표시됨)에 존재하는 고립 전압은 장치(10)에 대한 고압 및 저압 형태의 에너지 전달로 나타난다. 장치(10)는 프로세서 또는 로직 유닛의 일부분으로 제어 모듈을 포함한다. 로직 유닛은 프로세서, 마이크로프로세서, 멀티-모듈 소자, 또는 임의의 형태의 집적 회로일 수 있다. 로직 유닛은 전도성 물질(14, 16) 및 플레이트(20, 30)("플레이트1" 및 "플레이트2"로 표시됨)와 통신한다. 플레이트(20, 30)가 AC 공급원을 이용하여 전력을 공급받음에 따라, 로직 유닛은 에너지를 저장하였다가 나중에 이 에너지를 정보 전송에 사용한다.
이제 도 2C를 참조하면, 활성 주기 및 휴지 주기를 갖는 전력 사이클이 도시되고, 장치(10)의 전달 사이클이 전달 윈도로 도시된다. 본 발명에 따르면, 활성 주기 에너지의 지속시간이 전력 공급원으로부터 장치(10)로 전달된다. 그 후 휴지 상태 중, 장치(10)에 의해 저장된 에너지는 장치(10)로부터 프로브에 연결된 시스템으로 에너지를 전달하는 데 사용된다. 이러한 방식으로, 장치에 관련된 정보가 장치(10)로부터 프로브(20, 30)를 통해 프로브에 연결된 시스템에 전달될 수 있다. 본 발명의 다양한 형태에 따르면, 휴지 주기 중 장치(10)로부터 프로브(20, 30)의 시스템에 전달되는 정보는, 장치의 메모리에 저장된 정보에 기초한다. 따라서, 전력 공급원의 휴지 단계 또는 전달 윈도 중 "1"이 도시되더라도, 전력 공급원의 휴지 단계 또는 상태 중 전달되는 정보가 "0"일 수 있다.
본 발명의 일 형태에 따르면, 장치(10)에 물리적으로 연결된 물질과 용량성 플레이트/프로브 사이에 1 마이크로패럿 커패시터가 존재할 경우, 높은 고립 주파수에서, 이는 용량성 결합을 위해 필요한 저전압을 표시한다. 본 발명의 다른 형태에 따르면, 1 피코패럿 커패시터가 존재할 경우, 높은 전압이 필요할 수 있고, 이는 당 업자가 쉽게 인지가능한 사실이다. 실제로 공급되는 전류의 양은 예를 들어 도 1에 도시되는 바와 같이, 용량성 플레이트/프로브(20, 30) 사이에서 야기되는 전기 회로 사이의 임피던스에 좌우될 것이다. 따라서, 도 1A-1C의 용량성 플레이트(20) 및 용량성 플레이트(30)를 단락시키면, 상당한 전류가 공급되어, 예를 들어, 도 2에 도시되는 샘플링 증폭기에 의해 검출될 수 있다. 출력은 루프를 통과하는 전류 및, 제어 모듈(50)에 의해 야기되는 전류의 변조를 본질적으로 살펴보는 샘플링 증폭기를 통해 이루어진다.
본 발명의 다양한 형태에 따르면, 용량성 결합은 상호운용성을 위해 수정되는 DC 공급 장치인 장치(예를 들어, 칩 상에 안정한 전압을 제공하기 위해 정류기를 배치한 장치이며, 그 임피던스는 변조될 수 있음)와 함께 사용될 수 있다.
도 3A 및 3B를 이제 참조하면, 본 발명의 다양한 형태에 따라, 용량성 플레이트/프로브와, 정보 수신을 위해 여기에 연결된 시스템은, 다양한 구조적 구성요소 및 다른 장치들(예를 들어, 용량성 플레이트(20, 30)를 갖는 도 3A에 도시되는 형태의 관형 구조물(60))과 일체형으로 구성되거나 그 밖의 다른 방식으로 연계될 수 있다. 설명을 위해, IEM 또는 유사 장치(10)를 갖는 하나 이상의 의약 제품이 구조물 내로 삽입될 수 있다. 장치(10)는 수동으로 삽입될 수도 있고, 자동화 수단을 통해 자동적으로 삽입될 수도 있다. 장치가 구조물(60)을 통과함에 따라, 장치(10)는 튜브(60) 내의 용량성 플레이트(20, 30)에 의해 프로빙된다. 다양한 형태에서, 다른 장치 및/또는 구성요소들이 연계될 수 있다. 일례로서, 프로그래머블 장치가 용량성 결합 장치와 통신가능하게 연계되어, 용량성 결합 장치에 의해 도출되는 데이터 및/또는 정보를 수신 및/또는 송신할 수 있다. 상술한 설명을 계속하기 위해, 알약 형태일 수 있는 다수의 제품(10) 전부 또는 일부가 프로브/플레이트(20, 30)와 연계된 용량성 결합 시스템에 의해 프로빙되거나 "판독"되면, 용량성 결합 시스템은 추가적인 저장, 디스플레이, 조작, 등을 위해 디스플레이 장치와 함께 데이터베이스에, 예를 들어, 유선, 무선, 방식, 등으로 전달될 수 있다. 이러한 방식으로, 개별적인 데이터, 복수의 데이터, 다량의 데이터, 등이 다양한 용도를 위해 처리될 수 있다. 이러한 한가지 용도는 예를 들어, 정제 가압(tablet pressing) 또는 다른 프로세스와 같은 제작 프로세스 중, 약품 검증 프로세스 중, 약품 처방 프로세스 중, 등 공급 체인 응용분야에서 약품을 추적하는 것일 수 있다. 다양한 프로세스들이 상보적일 수 있고, 통합될 수 있다. 이러한 한가지 예는 번호 판독을 통한 검증이다. 유효할 경우, 예를 들어, 판독가능할 경우, 정제는 합격된다. 그렇지 않을 경우, 정제는 탈락한다. 따라서, 발진 전력 공급원과 함께 간단한 핸드-헬드형 판독기를 이용하여, 사용자나 치료 제공자가, 장치(10)를 갖는, 본 발명의 일 형태에 따라 알약 또는 정제일 수 있는, 제품을 프로빙할 수 있고, 장치(10)는 알약이 정품인지 또는 가품인지를 결정할 수 있다.
도 4A 및 4B를 이제 참조하면, 본 발명의 다른 형태에 따라, 장치(10)를 갖는 알약은 비-전도성 또는 불침투성 코팅인 코팅(74)을 갖는 형태로 도시되며, 알약 자체는 비-전도성 가루약을 포함한다. 예를 들어, 도시되는 바와 같이 원추-형상 영역일 수 있는, 영역(72)은 전도성 물질(70)(예를 들어, 다른 의약 물질, 부형제, 위약, 등과 혼합된 작은 입자 또는 입도의 전도성 물질)을 포함하여, 이 영역(72)이 전도성 영역으로 변환되게 된다. 예를 들어, 그래파이트 및 다른 전도성 물질이, 예를 들어, 10개 부분 중 한 부분에, 10개 부분 중 5개 부분에, 등등, 사용되어, 영역(72)이 전도성이 될 수 있다. 예를 들어, 내부에 전도성 입자를 갖는 겔 또는 액체 캡슐, 등, 다른 물질 및 조성도 가능하다. 따라서, 충분히 높은 주파수에서, 영역(72) 내의 전도성 물질(70)의 입자는 함께 단락될 수 있다. 전도성 물질(70)이 다양한 물질 및 폼 팩터(form factors)와, 이들의 조합(예를 들어, 다양한 크기의 입자, 와이어, 금속 박막, 스레드, 등)을 포함할 수 있다는 것을 당 업자라면 이해할 수 있을 것이다. 본 발명의 범위는 영역(72)에 사용되는 전도성 물질(70)의 타입이나 형태에 의해 제한되지 않는다.
본 발명의 다른 형태에 따르면, 전도성 물질은 다양한 방법 및 비율로 통합되거나 형성될 수 있다. 일례로서, 장치(10)는 "도넛-형상" 가루에 묻히거나 이러한 가루와 기계적으로 연계되고, 내부에 형성된 구멍은 전도성 입자로 충전되거나 그렇지 않을 경우 연계되어, 전도성 영역을 형성할 수 있다. 전도성 영역의 크기, 면적, 부피, 위치, 또는 다른 파라미터들은 여기서 설명되는 기능이 실행되는 정도에 따라 변할 수 있다.
본 발명의 다른 형태에 따르면, 그리고 도 5에 도시되는 바와 같이, 전도성 플레이트 또는 프로브(80, 82)는 데이터를 수집하기 위한 시스템에 연결된다. 프로브(80, 82)는 각각 물질(84, 86)에 대한 용량성 결합을 통해 장치(10)를 프로빙하는 데 사용된다. 임피던스 피드백 시스템은 이들을 서로 어느 정도 가깝게 유도하기 위해 사용될 수 있고, 전류가 소정 양에 도달하면, 거리를 측정하는데 사용될 수 있다. 충분히 높은 임피던스를 이용할 때, 이 시스템은, 장치(10)가 존재하는 지, 그리고 정확하게 작동하고 있는 지, 등을 검증하기 위해, 제작 환경과 같은 다양한 응용 분야에서 유용할 수 있다.
본 발명의 다른 형태에 따르면, 용량성 결합 프로브/플레이트와 장치(10) 사이의 거리 근접도는 프라이버시 측면(privacy aspects)을 촉진 및 증진시킬 수 있다. 소정 형태에서, 소정의 관련 장치들은 예를 들어, 시간에 맞추어 열리고, 닫히며, 위로 열리고, 등등과 같이 작동하는 CMOS 트랜지스터와 병렬로 쇼트키 다이오드를 갖는 회로를 포함할 수 있다. 다른 회로 설계 및 수정도 가능하다.
Claims (20)
- 섭취가능한 장치 외부에 위치하는 프로브를 사용하여 질의되도록 구성된 섭취가능한 장치로서,
제어 유닛 및 정보를 저장하기 위한 메모리를 포함하는 기판; 및
상기 기판과 물리적으로 연계되는 제 1 및 제 2 섭취가능한 플레이트(ingestible plate) - 제 1 섭취가능한 플레이트는 섭취가능한 장치 외부에 위치하는 프로브의 제 1 프로빙 플레이트에 통신 가능하게 연결되도록 구성되고, 제 2 섭취가능한 플레이트는 상기 프로브의 제 2 프로빙 플레이트에 통신 가능하게 연결되도록 구성되어 상기 제 1 섭취가능한 플레이트와 제 1 프로빙 플레이트 간에, 그리고 제 2 섭취 가능한 플레이트와 제 2 프로빙 플레이트 사이에 정보가 전달될 수 있음-;를 포함하고,
상기 섭취가능한 장치는 의약 제품과 물리적으로 연계되도록 구성되고;
상기 섭취가능한 장치는 의약 제품의 제조자로부터 의약 제품의 소비자까지의 공급 체인 전체를 통해 의약 제품의 진품 여부 및 근원을 검증하기 위해서 상기 프로브에 의해 질의되도록 구성되고;
상기 프로브는 상기 섭취가능한 장치의 기능을 검증하기 위해 상기 제 1 및 제 2 프로빙 플레이트의 대응하는 제 1 및 제 2 섭취가능한 플레이트에 대한 용량성 결합에 의해 상기 섭취가능한 장치에 전원을 공급하도록 구성되는,
섭취가능한 장치.
- 제 1 항에 있어서,
상기 제 1 및 제 2 섭취가능한 플레이트는 상기 제어 유닛에 통신가능하게 연결되는 것을 특징으로 하는 섭취가능한 장치.
- 제 1 항에 있어서,
상기 기판과 물리적으로 연계되는 전도성 물질 영역을 더 포함하는 것을 특징으로 하는 섭취가능한 장치.
- 제 3 항에 있어서,
상기 전도성 물질 영역은 전도성 물질과 적어도 하나의 다른 물질의 입자의 혼합물을 포함하는 것을 특징으로 하는 섭취가능한 장치.
- 제 4 항에 있어서,
상기 적어도 하나의 다른 물질은 기본적으로 적어도 하나의 의약 물질, 적어도 하나의 부형제, 또는 적어도 하나의 위약(placebo material)으로 구성되는 그룹으로부터 선택되는 것을 특징으로 하는 섭취가능한 장치.
- 제 1 항에 있어서,
상기 제 1 및 제 2 섭취가능한 플레이트는 서로 유사하지 않은 물질을 각각 포함하는 것을 특징으로 하는 섭취가능한 장치.
- 제 6 항에 있어서,
상기 제 1 및 제 2 섭취가능한 플레이트는 전압 전위 차(voltage potential difference)를 제공하도록 구성되고,
상기 제어 유닛은, 상기 제 1 및 제 2 섭취가능한 플레이트 사이의 전도도가 변화되어 전류 흐름의 크기가 달라져 신호에 정보가 인코딩되고 인코딩된 정보가 수신기에 의해 원격으로 검출될 수 있도록, 상기 제 1 및 제 2 섭취가능한 플레이트 사이의 전도도를 변화시키도록 구성된,
섭취가능한 장치.
- 삭제
- 삭제
- 삭제
- 출발지로부터 종착지까지 제품의 외부에 위치하는 프로브를 사용하여 질의되도록 구성되는 제품 추적 시스템으로서,
프로브; 및
섭취가능한 장치;
를 포함하며,
상기 프로브는,
전력 공급원;
정보를 수신 및 송신하도록 구성되고 상기 전력 공급원에 연결되는 프로세서; 및
상기 프로세서에 연결되는 제 1 프로빙 플레이트 및 제 2 프로빙 플레이트;
를 포함하되,
상기 전력 공급원은 상기 제 1 및 제 2 프로빙 플레이트에 출력을 생성하도록 상기 프로세서에 의해 제어되도록 구성되고,
상기 섭취가능한 장치는,
제어 유닛과 정보를 저장하도록 구성된 메모리를 포함하는 기판; 및
상기 기판과 물리적으로 연계되는 제 1 및 제 2 섭취가능한 플레이트;
를 포함하고,
상기 섭취가능한 장치는 상기 프로브의 상기 제 1 및 제 2 프로빙 플레이트에 통신가능하게 연결되도록 구성되어 상기 섭취가능한 장치와 상기 프로브 사이에 정보가 전달될 수 있으며,
상기 섭취가능한 장치는 의약 제품과 물리적으로 연계되도록 구성되고;
상기 섭취가능한 장치는 의약 제품의 제조자로부터 의약 제품의 소비자까지의 공급 체인 전체를 통해 의약 제품의 진품 여부 및 근원을 검증하기 위해서 상기 프로브에 의해 질의되도록 구성되고;
상기 프로브는 상기 섭취가능한 장치의 기능을 검증하기 위해 상기 제 1 및 제 2 프로빙 플레이트의 대응하는 제 1 및 제 2 섭취가능한 플레이트에 대한 용량성 결합에 의해 상기 섭취가능한 장치에 전원을 공급하도록 구성되는,
출발지로부터 종착지까지의 제품 추적 시스템.
- 제 11 항에 있어서,
상기 제 1 및 제 2 프로빙 플레이트는 서로 면하여 이격 거리를 갖는 갭을 형성하되, 상기 섭취가능한 장치가 상기 형성된 갭 내에서 상기 제 1 프로빙 플레이트와 상기 제 2 프로빙 플레이트 사이에 위치할 때 상기 섭취가능한 장치가 상기 프로브와 통신하게 되는 이격 거리를 갖는 갭을 형성하는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
상기 제 1 및 제 2 프로빙 플레이트는 동일 평면에 위치하고 나란히 놓여서, 상기 섭취가능한 장치가 상기 프로브에 인접하여 놓일 때 상기 섭취가능한 장치가 상기 프로브와 통신하게 되는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
상기 프로브는 상기 제 1 및 제 2 프로빙 플레이트를 내부에 갖는 튜브를 더 포함하는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
상기 제 1 및 제 2 섭취가능한 플레이트는 상기 제어 유닛에 통신가능하게 연결되는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
상기 기판과 물리적으로 연계되는 전도성 물질 영역을 더 포함하는 것을 특징으로 하는 제품 추적 시스템.
- 제 16 항에 있어서,
상기 전도성 물질 영역은 전도성 물질과 적어도 하나의 다른 물질의 입자의 혼합물을 포함하는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
상기 제 1 및 제 2 섭취가능한 플레이트는 전도성 잉크로 제조되는 것을 특징으로 하는 제품 추적 시스템.
- 제 11 항에 있어서,
외부 장치;
를 더 포함하되,
상기 섭취가능한 장치는 상기 외부 장치와 통신하도록 구성되는 것을 특징으로 하는 제품 추적 시스템.
- 제 19 항에 있어서,
상기 섭취가능한 장치는 상기 외부 장치와 통신하도록 구성되는 통신 소자를 포함하되, 상기 통신 소자는 전압 전위 차를 제공하도록 선택된 제 1 물질 및 이와 상이한 제 2 물질을 포함하고,
상기 제어 유닛은, 상기 제 1 및 제 2 물질 사이의 전도도가 변화되어 전류 흐름의 크기가 달라져 신호에 정보가 인코딩되어 인코딩된 정보가 생성되고 인코딩된 정보는 수신기에 의해 원격으로 검출되도록, 상기 제 1 및 제 2 물질 사이의 전도도를 변화시키도록 구성된,
제품 추적 시스템.
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