|
US2588623A
(en)
|
1948-05-10 |
1952-03-11 |
Eliscu Frank |
Surgical instrument for intradermal injection of fluids
|
|
US3467096A
(en)
|
1966-04-12 |
1969-09-16 |
Ferrell S Horn |
Multiple hypodermic syringe arrangement
|
|
US3572336A
(en)
|
1968-04-30 |
1971-03-23 |
Daniel R Hershberg |
Syringe
|
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
JPS5927900A
(ja)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
固定化オリゴヌクレオチド
|
|
FR2540122B1
(fr)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
|
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
|
US5118800A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
|
FR2567892B1
(fr)
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
|
US4695273A
(en)
|
1986-04-08 |
1987-09-22 |
I-Flow Corporation |
Multiple needle holder and subcutaneous multiple channel infusion port
|
|
JPS638396A
(ja)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
ポリ標識化オリゴヌクレオチド誘導体
|
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
|
DE3738460A1
(de)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
Modifizierte oligonukleotide
|
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
|
DE69034150T2
(de)
|
1989-10-24 |
2005-08-25 |
Isis Pharmaceuticals, Inc., Carlsbad |
2'-Modifizierte Oligonukleotide
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
|
AU7579991A
(en)
|
1990-02-20 |
1991-09-18 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
|
GB9009980D0
(en)
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
|
DK0455905T3
(da)
|
1990-05-11 |
1998-12-07 |
Microprobe Corp |
Dipsticks til nukleinsyrehybridiseringsassays og fremgangsmåde til kovalent immobilisering af oligonukleotider
|
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
|
ATE198598T1
(de)
|
1990-11-08 |
2001-01-15 |
Hybridon Inc |
Verbindung von mehrfachreportergruppen auf synthetischen oligonukleotiden
|
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
EP0538194B1
(de)
|
1991-10-17 |
1997-06-04 |
Novartis AG |
Bicyclische Nukleoside, Oligonukleotide, Verfahren zu deren Herstellung und Zwischenprodukte
|
|
US5359044A
(en)
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
|
FR2687679B1
(fr)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
Oligothionucleotides.
|
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
|
EP0577558A2
(de)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte
|
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
|
CA2156288C
(en)
|
1993-02-19 |
2005-10-18 |
Junichi Yano |
Glycerol derivative, device and pharmaceutical composition
|
|
ES2107205T3
(es)
|
1993-03-30 |
1997-11-16 |
Sanofi Sa |
Analogos de nucleosidos aciclicos y secuencias oligonucleotidas que los contienen.
|
|
DE4311944A1
(de)
|
1993-04-10 |
1994-10-13 |
Degussa |
Umhüllte Natriumpercarbonatpartikel, Verfahren zu deren Herstellung und sie enthaltende Wasch-, Reinigungs- und Bleichmittelzusammensetzungen
|
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
|
US5446137B1
(en)
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
|
US5464395A
(en)
|
1994-04-05 |
1995-11-07 |
Faxon; David P. |
Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
|
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US5713863A
(en)
|
1996-01-11 |
1998-02-03 |
Interventional Technologies Inc. |
Catheter with fluid medication injectors
|
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
US5994316A
(en)
|
1996-02-21 |
1999-11-30 |
The Immune Response Corporation |
Method of preparing polynucleotide-carrier complexes for delivery to cells
|
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
|
US20030073908A1
(en)
|
1996-04-26 |
2003-04-17 |
2000 Injectx, Inc. |
Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells
|
|
JP2002515786A
(ja)
|
1996-06-28 |
2002-05-28 |
ソントラ メディカル,エル.ピー. |
経皮輸送の超音波増強
|
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
|
JP3756313B2
(ja)
|
1997-03-07 |
2006-03-15 |
武 今西 |
新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
|
|
US6761726B1
(en)
|
1998-05-15 |
2004-07-13 |
Pyng Medical Corp. |
Method and apparatus for the intraosseous introduction of a device such as an infusion tube
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
JP2002508299A
(ja)
*
|
1997-09-19 |
2002-03-19 |
セクイター, インク. |
センスmRNA治療
|
|
US6077251A
(en)
|
1997-10-30 |
2000-06-20 |
Ting; Windsor |
Medicinal agent administration system
|
|
AU744755B2
(en)
|
1997-11-12 |
2002-03-07 |
Brigham And Women's Hospital |
The translation enhancer element of the human amyloid precursor protein gene
|
|
US6548633B1
(en)
|
1998-12-22 |
2003-04-15 |
Genset, S.A. |
Complementary DNA's encoding proteins with signal peptides
|
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6267987B1
(en)
|
1997-12-12 |
2001-07-31 |
Samyang Corporation |
Positively charged poly[alpha-(omega-aminoalkyl) glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
|
WO1999034857A1
(en)
|
1998-01-08 |
1999-07-15 |
Sontra Medical, Inc. |
Sonophoretic enhanced transdermal transport
|
|
KR20010071279A
(ko)
|
1998-05-20 |
2001-07-28 |
추후제출 |
간세포를 표적으로하는 폴리에틸렌 글리콜-접합된폴리-l-리신 고분자로된 유전자 운반체
|
|
EP1117720A4
(en)
|
1998-07-13 |
2001-11-14 |
Expression Genetics Inc |
POLYESTER POLY-L-LYSINE ANALOG USED AS A BIODEGRADABLE SOLUBLE GENE CONVEYOR
|
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
EP1818017A3
(en)
|
1999-03-01 |
2007-08-29 |
Cytyc Corporation |
Apparatus and kits for simultaneous delivery of a substance to multiple breast milk ducts
|
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
|
AU776362B2
(en)
|
1999-05-04 |
2004-09-09 |
Roche Innovation Center Copenhagen A/S |
L-ribo-LNA analogues
|
|
US7171264B1
(en)
|
1999-05-10 |
2007-01-30 |
Genetronics, Inc. |
Intradermal delivery of active agents by needle-free injection and electroporation
|
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
|
CA2311201A1
(en)
|
1999-08-05 |
2001-02-05 |
Genset S.A. |
Ests and encoded human proteins
|
|
US6551338B1
(en)
|
1999-09-01 |
2003-04-22 |
Mcgill University |
Method and device for myogenesis and angiogenesis of the heart
|
|
SE515932C2
(sv)
|
1999-12-23 |
2001-10-29 |
Prostalund Operations Ab |
Sätt och anordning vid behandling av prostata
|
|
US7468275B2
(en)
|
2000-01-28 |
2008-12-23 |
The Scripps Research Institute |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
AU3117101A
(en)
|
2000-01-28 |
2001-08-07 |
Scripps Research Inst |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
US6468247B1
(en)
|
2000-04-21 |
2002-10-22 |
Mark Zamoyski |
Perfusion device for localized drug delivery
|
|
US6537242B1
(en)
|
2000-06-06 |
2003-03-25 |
Becton, Dickinson And Company |
Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
|
|
US6607513B1
(en)
|
2000-06-08 |
2003-08-19 |
Becton, Dickinson And Company |
Device for withdrawing or administering a substance and method of manufacturing a device
|
|
US20050181033A1
(en)
|
2000-06-29 |
2005-08-18 |
Dekker John P.Iii |
Method for delivering interferons to the intradermal compartment
|
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
JP4413493B2
(ja)
|
2000-10-04 |
2010-02-10 |
サンタリス ファーマ アー/エス |
プリンlna類似体の改善された合成方法
|
|
US7628780B2
(en)
|
2001-01-13 |
2009-12-08 |
Medtronic, Inc. |
Devices and methods for interstitial injection of biologic agents into tissue
|
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
|
US6625486B2
(en)
|
2001-04-11 |
2003-09-23 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for intracellular delivery of an agent
|
|
PT1857122E
(pt)
|
2001-06-05 |
2011-03-07 |
Curevac Gmbh |
Arnm estabilizado com teor de g/c aumentado, codificando para um antigénio viral
|
|
WO2003002069A2
(en)
|
2001-06-29 |
2003-01-09 |
Becton, Dickinson And Company |
Intradermal delivery of vaccines and gene therapeutic agents via microcannula
|
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
|
IL161100A0
(en)
|
2001-09-28 |
2004-08-31 |
Max Planck Gesellschaft |
Identification of novel genes coding for small temporal rnas
|
|
US7429258B2
(en)
|
2001-10-26 |
2008-09-30 |
Massachusetts Institute Of Technology |
Microneedle transport device
|
|
US7585491B2
(en)
|
2002-12-13 |
2009-09-08 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
US7722595B2
(en)
|
2002-05-06 |
2010-05-25 |
Becton, Dickinson And Company |
Method and device for controlling drug pharmacokinetics
|
|
CN100435882C
(zh)
|
2002-05-08 |
2008-11-26 |
加利福尼亚大学董事会 |
用成纤维细胞治疗心律失常的系统和方法
|
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
|
US20040009180A1
(en)
|
2002-07-11 |
2004-01-15 |
Allergan, Inc. |
Transdermal botulinum toxin compositions
|
|
WO2004012605A1
(en)
|
2002-08-01 |
2004-02-12 |
Abbott Laboratories Vascular Enterprises, Limited |
Apparatus for sealing a puncture by causing a reduction in the circumference of the puncture
|
|
JP2006508056A
(ja)
*
|
2002-08-28 |
2006-03-09 |
イミュネックス・コーポレーション |
心臓血管疾患を治療するための組成物および方法
|
|
BR0313890A
(pt)
|
2002-08-30 |
2005-07-26 |
Becton Dickinson Co |
Método de controle da farmacocinética de compostos imunomoduladores
|
|
US6896666B2
(en)
|
2002-11-08 |
2005-05-24 |
Kochamba Family Trust |
Cutaneous injection delivery under suction
|
|
EP1592791A2
(en)
*
|
2003-02-10 |
2005-11-09 |
National Institute of Advanced Industrial Science and Technology |
Regulation of gene expression by dna interference
|
|
US20040226556A1
(en)
|
2003-05-13 |
2004-11-18 |
Deem Mark E. |
Apparatus for treating asthma using neurotoxin
|
|
EP1648914A4
(en)
|
2003-07-31 |
2009-12-16 |
Regulus Therapeutics Inc |
OLIGOMERIC COMPOUNDS AND COMPOSITIONS USEFUL FOR MODULATING SMALL NON-CODING RNA
|
|
US7998119B2
(en)
|
2003-11-18 |
2011-08-16 |
Nano Pass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
|
US7150726B2
(en)
|
2004-01-23 |
2006-12-19 |
Norfolk Medical |
Device for subcutaneous infusion of fluids
|
|
WO2005072710A2
(en)
|
2004-01-28 |
2005-08-11 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
|
EP3251710A1
(en)
|
2004-04-12 |
2017-12-06 |
Allergan, Inc. |
Multi-site injection system
|
|
US20080103053A1
(en)
|
2005-11-22 |
2008-05-01 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
|
US8338648B2
(en)
|
2004-06-12 |
2012-12-25 |
Signum Biosciences, Inc. |
Topical compositions and methods for epithelial-related conditions
|
|
US7527947B2
(en)
|
2004-06-14 |
2009-05-05 |
Novozymes A/S |
Signal peptide for producing a polypeptide
|
|
EP1768742A4
(en)
|
2004-07-06 |
2007-10-17 |
Transpharma Medical Ltd |
ADMINISTRATION SYSTEM FOR TRANSDERMAL IMMUNIZATION
|
|
WO2006028245A1
(ja)
|
2004-09-07 |
2006-03-16 |
Kawajun Co., Ltd. |
商品自動前出し棚装置
|
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
|
CA2587216C
(en)
|
2004-11-18 |
2014-11-18 |
Nanopass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
|
EP1856179B1
(en)
|
2004-12-10 |
2013-05-15 |
Kala Pharmaceuticals, Inc. |
Functionalized poly (ether-anhydride) block copolymers
|
|
US20060263338A1
(en)
|
2005-03-04 |
2006-11-23 |
Jacoby Douglas B |
Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
|
|
JP4793806B2
(ja)
|
2005-03-22 |
2011-10-12 |
Tti・エルビュー株式会社 |
イオントフォレーシス装置
|
|
US9085774B2
(en)
*
|
2005-04-19 |
2015-07-21 |
Basf Plant Science Gmbh |
Methods controlling gene expression
|
|
US7850656B2
(en)
|
2005-04-29 |
2010-12-14 |
Warsaw Orthopedic, Inc. |
Devices and methods for delivering medical agents
|
|
SI2002003T1
(sl)
|
2005-05-27 |
2016-05-31 |
Ospedale San Raffaele S.R.L. |
Genski vektor, ki vsebuje mi-RNA
|
|
US7691086B2
(en)
|
2005-06-14 |
2010-04-06 |
Tengiz Tkebuchava |
Catheter for introduction of medications to the tissues of a heart or other organ
|
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
US8105813B2
(en)
|
2005-06-30 |
2012-01-31 |
Archemix Corp. |
Materials and methods for the generation of fully 2′-modified nucleic acid transcripts
|
|
ES2937245T3
(es)
*
|
2005-08-23 |
2023-03-27 |
Univ Pennsylvania |
ARN que contiene nucleósidos modificados y métodos de uso del mismo
|
|
WO2007025008A2
(en)
|
2005-08-24 |
2007-03-01 |
The Scripps Research Institute |
Translation enhancer-element dependent vector systems
|
|
US20070185432A1
(en)
|
2005-09-19 |
2007-08-09 |
Transport Pharmaceuticals, Inc. |
Electrokinetic system and method for delivering methotrexate
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
US8012096B2
(en)
|
2005-10-17 |
2011-09-06 |
Cardiogenesis Corporation |
Surgical device and method for performing combination revascularization and therapeutic substance delivery to tissue
|
|
CN101384273B
(zh)
|
2006-01-05 |
2013-07-10 |
俄亥俄州立大学研究基金会 |
胰腺内分泌和腺泡肿瘤中的微小rna表达异常
|
|
CN103642900B
(zh)
|
2006-01-05 |
2016-04-13 |
俄亥俄州立大学研究基金会 |
用于诊断和治疗实体癌的基于微小rna的方法和组合物
|
|
EP1984381B1
(en)
|
2006-01-27 |
2010-09-29 |
Isis Pharmaceuticals, Inc. |
6-modified bicyclic nucleic acid analogs
|
|
CA2638844C
(en)
|
2006-03-02 |
2016-05-03 |
Thomas D. Schmittgen |
Microrna expression profile associated with pancreatic cancer
|
|
US7361908B2
(en)
|
2006-04-13 |
2008-04-22 |
The Hong Kong Polytechnic University |
Radiation dose estimation for radiochromic films based on measurements at multiple absorption peaks
|
|
EP2073735B1
(en)
|
2006-09-08 |
2010-11-24 |
Arbel Medical Ltd. |
Device for combined treatment
|
|
CA2663003C
(en)
|
2006-09-08 |
2018-02-13 |
Justin Hanes |
Compositions and methods for enhancing transport through mucus
|
|
WO2008036765A2
(en)
|
2006-09-19 |
2008-03-27 |
Asuragen, Inc. |
Micrornas differentially expressed in pancreatic diseases and uses thereof
|
|
EP2087135B8
(en)
|
2006-11-01 |
2013-07-24 |
The Ohio State University Research Foundation |
Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma
|
|
CN101622349A
(zh)
|
2006-12-08 |
2010-01-06 |
奥斯瑞根公司 |
作为治疗性干预靶标的miR-21调节的基因和途径
|
|
EP2207891B1
(en)
|
2006-12-22 |
2012-07-25 |
Archemix LLC |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
US7699803B2
(en)
|
2007-01-03 |
2010-04-20 |
Medtronic Vascular, Inc. |
Devices and methods for injection of multiple-component therapies
|
|
WO2008091799A2
(en)
*
|
2007-01-22 |
2008-07-31 |
The Trustees Of Columbia University In The City Of New York |
Cell-based methods for identifying inhibitors of parkinson's disease-associated lrrk2 mutants
|
|
US8029496B2
(en)
|
2007-03-05 |
2011-10-04 |
Ebrahim Versi |
Method and device for delivering drug to the trigone of the bladder
|
|
BRPI0810969A2
(pt)
|
2007-04-27 |
2015-01-27 |
Echo Therapeutics Inc |
Dispositivo de permeação da pele para a detecção de analito ou liberação transdermal de fármaco
|
|
WO2008147974A1
(en)
|
2007-05-23 |
2008-12-04 |
University Of South Florida |
Micro-rnas modulating immunity and inflammation
|
|
WO2008154098A2
(en)
|
2007-06-07 |
2008-12-18 |
Wisconsin Alumni Research Foundation |
Reagents and methods for mirna expression analysis and identification of cancer biomarkers
|
|
US8367318B2
(en)
*
|
2007-07-23 |
2013-02-05 |
Dharmacon, Inc. |
Screening of micro-RNA cluster inhibitor pools
|
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
|
SG183726A1
(en)
|
2007-08-14 |
2012-09-27 |
Hutchinson Fred Cancer Res |
Needle array assembly and method for delivering therapeutic agents
|
|
US20130108663A1
(en)
|
2007-09-14 |
2013-05-02 |
Vrije Universiteit Brussel |
Enhancing the t-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and their use in vaccination
|
|
US20090137945A1
(en)
|
2007-11-28 |
2009-05-28 |
Claire Marquez |
Electro Collagen Induction Therapy Device
|
|
AU2008329755A1
(en)
|
2007-11-30 |
2009-06-04 |
The Ohio State University Research Foundation |
MicroRNA expression profiling and targeting in peripheral blood in lung cancer
|
|
WO2009075886A1
(en)
|
2007-12-11 |
2009-06-18 |
The Scripps Research Institute |
Compositions and methods related to mrna translational enhancer elements
|
|
JPWO2009093384A1
(ja)
*
|
2008-01-24 |
2011-05-26 |
独立行政法人産業技術総合研究所 |
ポリヌクレオチド及びポリヌクレオチド類似体並びにこれらを用いた遺伝子発現制御方法
|
|
US20090263803A1
(en)
|
2008-02-08 |
2009-10-22 |
Sylvie Beaudenon |
Mirnas differentially expressed in lymph nodes from cancer patients
|
|
US20110052502A1
(en)
|
2008-02-28 |
2011-03-03 |
The Ohio State University Research Foundation |
MicroRNA Signatures Associated with Human Chronic Lymphocytic Leukemia (CCL) and Uses Thereof
|
|
WO2009108891A2
(en)
|
2008-02-29 |
2009-09-03 |
Egen, Inc. |
Modified poloxamers for gene expression and associated methods
|
|
CN102027043A
(zh)
|
2008-03-14 |
2011-04-20 |
艾根股份有限公司 |
生物可降解的交联支链聚(亚烷基亚胺)
|
|
EP2112235A1
(en)
|
2008-04-24 |
2009-10-28 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for microRNA expression profiling of nasopharyngeal carcinoma
|
|
US9394538B2
(en)
*
|
2008-05-07 |
2016-07-19 |
Shi-Lung Lin |
Development of universal cancer drugs and vaccines
|
|
WO2009147641A2
(en)
|
2008-06-06 |
2009-12-10 |
Wockhardt Research Centre |
A device and a system for delivery of biological material
|
|
US7799016B2
(en)
|
2008-06-20 |
2010-09-21 |
Pharmaco-Kinesis Corporation |
Magnetic breather pump and a method for treating a brain tumor using the same
|
|
US8996104B2
(en)
|
2008-06-25 |
2015-03-31 |
Fe3 Medical, Inc. |
Patches and method for the transdermal delivery of a therapeutically effective amount of iron
|
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
|
WO2010018563A2
(en)
|
2008-08-12 |
2010-02-18 |
Rosetta Genomics Ltd. |
Compositions and methods for the prognosis of lymphoma
|
|
EP2328650B1
(en)
|
2008-08-26 |
2016-04-06 |
Cook Medical Technologies LLC |
Balloon catheters having a plurality of needles for the injection of one or more therapeutic agents
|
|
US20120100558A1
(en)
*
|
2008-09-08 |
2012-04-26 |
Hanash Samir M |
Lung cancer diagnosis
|
|
EP2349100B1
(en)
|
2008-10-10 |
2014-07-16 |
Kirk Promotion LTD. |
Infusion of drugs
|
|
ITVI20080239A1
(it)
|
2008-10-14 |
2010-04-15 |
Antoine Assaf |
Apparato medicale per iniezioni multiple.
|
|
WO2010048228A2
(en)
|
2008-10-20 |
2010-04-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of transthyretin
|
|
EP2364362B1
(en)
|
2008-11-12 |
2015-10-21 |
Ospedale San Raffaele S.r.l. |
Gene vector for inducing transgene-specific immune tolerance
|
|
WO2010066384A1
(en)
|
2008-12-10 |
2010-06-17 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for micro-rna expression profiling of cancer stem cells
|
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
|
US8460696B2
(en)
|
2009-03-20 |
2013-06-11 |
Egen, Inc. |
Polyamine derivatives
|
|
WO2010129860A2
(en)
|
2009-05-08 |
2010-11-11 |
The Ohio State University Research Foundation |
Microrna expression profiling and targeting in chronic obstructive pulmonary disease (copd) lung tissue and methods of use thereof
|
|
KR102066189B1
(ko)
|
2009-06-10 |
2020-01-14 |
알닐람 파마슈티칼스 인코포레이티드 |
향상된 지질 조성물
|
|
EP2451823A4
(en)
|
2009-07-06 |
2013-07-03 |
Alnylam Pharmaceuticals Inc |
COMPOSITIONS AND METHODS FOR ENHANCING THE PRODUCTION OF A BIOLOGICAL PRODUCT
|
|
EP3165234B1
(de)
|
2009-07-31 |
2019-04-03 |
ethris GmbH |
Rna mit einer kombination aus unmodifizierten und modifizierten nucleotiden zur proteinexpression
|
|
WO2011028175A1
(en)
|
2009-09-01 |
2011-03-10 |
Agency For Science, Technology And Research |
Terminal device and method for processing an encrypted bit stream
|
|
RS58405B1
(sr)
|
2009-12-01 |
2019-04-30 |
Translate Bio Inc |
Stereoidni derivati za isporuku irnk u humanim genetskim oboljenjima
|
|
MX348474B
(es)
|
2009-12-23 |
2017-06-14 |
Novartis Ag * |
Lipidos, composiciones de lipido, y metodos de uso de los mismos.
|
|
WO2011076142A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expession profiling in plasma of colorectal cancer
|
|
WO2011076143A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expression profiling of lung cancer
|
|
EP2341145A1
(en)
|
2009-12-30 |
2011-07-06 |
febit holding GmbH |
miRNA fingerprint in the diagnosis of diseases
|
|
US8846631B2
(en)
*
|
2010-01-14 |
2014-09-30 |
Regulus Therapeutics Inc. |
MicroRNA compositions and methods
|
|
WO2011094683A2
(en)
|
2010-01-29 |
2011-08-04 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Method of identifying myelodysplastic syndromes
|
|
EP2354246A1
(en)
|
2010-02-05 |
2011-08-10 |
febit holding GmbH |
miRNA in the diagnosis of ovarian cancer
|
|
WO2011113030A2
(en)
|
2010-03-11 |
2011-09-15 |
H.Lee Moffitt Cancer Center & Research Institute |
Human cancer micro-rna expression profiles predictive of chemo-response
|
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
|
CA2795695A1
(en)
*
|
2010-04-09 |
2011-10-13 |
The University Of Tokyo |
Microrna-controlled recombinant vaccinia virus and use thereof
|
|
CA2796464C
(en)
|
2010-04-16 |
2021-08-03 |
Immune Disease Institute, Inc. |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
US9629979B2
(en)
|
2010-04-28 |
2017-04-25 |
Sanovas, Inc. |
Pressure/Vacuum actuated catheter drug delivery probe
|
|
WO2011157294A1
(en)
|
2010-06-16 |
2011-12-22 |
Universita' Degli Studi Di Padova |
Compositions for use in treating or preventing cancer, breast cancer, lung cancer, ovarian cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto
|
|
US20120158100A1
(en)
|
2010-06-21 |
2012-06-21 |
Kevin Schomacker |
Driving Microneedle Arrays into Skin and Delivering RF Energy
|
|
US8351828B2
(en)
|
2010-06-30 |
2013-01-08 |
Eastman Kodak Company |
Printer having an alternate scavenger geometry
|
|
US8353871B2
(en)
|
2010-07-05 |
2013-01-15 |
Roller Jet Ltd. |
Drug delivery device with needles and roller
|
|
HUE026646T2
(en)
|
2010-07-06 |
2016-07-28 |
Glaxosmithkline Biologicals Sa |
Preferred liposomes containing lipids of PKA value for delivery of RNA
|
|
RU2625546C2
(ru)
|
2010-07-06 |
2017-07-14 |
Новартис Аг |
Катионные эмульсии "масло-в-воде"
|
|
HRP20161352T1
(hr)
|
2010-07-06 |
2016-12-02 |
Glaxosmithkline Biologicals Sa |
Čestice nalik na virione za unos samoreplicirajućih molekula rna
|
|
WO2012009644A2
(en)
|
2010-07-16 |
2012-01-19 |
Arizona Board Of Regents |
Methods to identify synthetic and natural rna elements that enhance protein translation
|
|
US8822663B2
(en)
*
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
|
DK4226941T3
(da)
|
2010-08-31 |
2024-12-02 |
Glaxosmithkline Biologicals Sa |
Pegylerede liposomer til levering af immunogen-kodende rna
|
|
CN103384515B
(zh)
|
2010-08-31 |
2017-02-15 |
诺华有限公司 |
适用于脂质体递送编码蛋白质的rna的脂质
|
|
CA2821992A1
(en)
|
2010-10-01 |
2012-04-05 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
WO2013086505A1
(en)
|
2011-12-09 |
2013-06-13 |
Vanderbilt University |
Integrated organ-on-chip system and applications of the same
|
|
EP2635254B1
(en)
|
2010-11-05 |
2019-05-15 |
The John Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
|
CA2862765A1
(en)
|
2011-01-04 |
2012-07-12 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
|
US9999673B2
(en)
|
2011-01-11 |
2018-06-19 |
Alnylam Pharmaceuticals, Inc. |
PEGylated lipids and their use for drug delivery
|
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
|
US10086043B2
(en)
|
2011-04-03 |
2018-10-02 |
The General Hospital Corporation |
Efficient protein expression in vivo using modified RNA (MOD-RNA)
|
|
US20140113978A1
(en)
|
2011-05-01 |
2014-04-24 |
University Of Rochester |
Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof
|
|
EP2944961A1
(en)
|
2011-05-06 |
2015-11-18 |
XenTech |
Markers for cancer prognosis and therapy and methods of use
|
|
ES2610245T3
(es)
|
2011-07-15 |
2017-04-26 |
Leo Pharma A/S |
Perfilado de microARN para el diagnóstico en linfoma cutáneo de células T (CTCL)
|
|
US20150080243A1
(en)
|
2011-09-01 |
2015-03-19 |
Allegro Diagnostics Corp. |
Methods and compositions for detecting cancer based on mirna expression profiles
|
|
HRP20220250T1
(hr)
|
2011-10-03 |
2022-04-29 |
Modernatx, Inc. |
Modificirani nukleozidi, nukleotidi i nukleinske kiseline, te njihove uporabe
|
|
WO2013066678A1
(en)
|
2011-10-26 |
2013-05-10 |
Georgetown University |
Microrna expression profiling of thyroid cancer
|
|
TR201111743A2
(tr)
|
2011-11-28 |
2012-04-24 |
Nesl�Han G�Rsoy Reyhan |
Kanser tedavisinde kullanılmak üzere yağ bazlı nanotaşıyıcı sistemler.
|
|
US9725687B2
(en)
|
2011-12-09 |
2017-08-08 |
President And Fellows Of Harvard College |
Integrated human organ-on-chip microphysiological systems
|
|
WO2013086502A1
(en)
|
2011-12-09 |
2013-06-13 |
President And Fellows Of Harvard College |
Organ chips and uses thereof
|
|
SI2791160T1
(sl)
|
2011-12-16 |
2022-07-29 |
Modernatx, Inc. |
Sestave modificirane MRNA
|
|
WO2013103659A1
(en)
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
|
AU2013222238A1
(en)
|
2012-02-22 |
2014-09-18 |
Northwestern University |
Nanostructures for treating cancers and other conditions
|
|
EP2819651A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget AS |
Use of an antibody and a particulate immunomodulator in therapy
|
|
EP2819652A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget As |
Use of a particulate immunomodulator in cancer therapy
|
|
US20130236504A1
(en)
|
2012-03-06 |
2013-09-12 |
Medical University Of South Carolina |
Delivery System for Enhancing Drug Efficacy
|
|
HK1206612A1
(en)
*
|
2012-04-02 |
2016-01-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
|
AU2013243952A1
(en)
*
|
2012-04-02 |
2014-10-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
SMT202200337T1
(it)
*
|
2012-11-26 |
2022-09-14 |
Modernatx Inc |
Rna modificato al livello del terminale
|
|
AU2013374345A1
(en)
|
2013-01-17 |
2015-08-06 |
Moderna Therapeutics, Inc. |
Signal-sensor polynucleotides for the alteration of cellular phenotypes
|
|
WO2015007871A2
(en)
|
2013-07-17 |
2015-01-22 |
Ospedale San Raffaele S.R.L. |
Micrornas and autoimmune-immune mediated inflammatory disease
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3169783A4
(en)
|
2014-07-17 |
2018-10-03 |
Modernatx, Inc. |
Terminal modifications of polynucleotides
|
|
EP3461904A1
(en)
|
2014-11-10 |
2019-04-03 |
ModernaTX, Inc. |
Alternative nucleic acid molecules containing reduced uracil content and uses thereof
|
|
JP6912384B2
(ja)
|
2015-04-22 |
2021-08-04 |
キュアバック アーゲー |
癌疾患の処置のための、rna含有組成物
|
|
PL3394093T3
(pl)
|
2015-12-23 |
2022-05-16 |
Modernatx, Inc. |
Metody stosowania polinukleotydów kodujących ligand ox40
|