JP2017511344A5 - - Google Patents

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JP2017511344A5
JP2017511344A5 JP2016561619A JP2016561619A JP2017511344A5 JP 2017511344 A5 JP2017511344 A5 JP 2017511344A5 JP 2016561619 A JP2016561619 A JP 2016561619A JP 2016561619 A JP2016561619 A JP 2016561619A JP 2017511344 A5 JP2017511344 A5 JP 2017511344A5
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dried dispersion
pharmaceutical composition
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JP6543268B2 (ja
JP2017511344A (ja
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Priority claimed from PCT/US2015/025722 external-priority patent/WO2015160787A1/en
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JP2016561619A 2014-04-15 2015-04-14 嚢胞性線維症膜コンダクタンス調節因子が媒介する疾患を処置するための医薬組成物 Active JP6543268B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461979848P 2014-04-15 2014-04-15
US61/979,848 2014-04-15
US201462059287P 2014-10-03 2014-10-03
US62/059,287 2014-10-03
PCT/US2015/025722 WO2015160787A1 (en) 2014-04-15 2015-04-14 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

Publications (3)

Publication Number Publication Date
JP2017511344A JP2017511344A (ja) 2017-04-20
JP2017511344A5 true JP2017511344A5 (enExample) 2018-05-31
JP6543268B2 JP6543268B2 (ja) 2019-07-10

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JP2016561619A Active JP6543268B2 (ja) 2014-04-15 2015-04-14 嚢胞性線維症膜コンダクタンス調節因子が媒介する疾患を処置するための医薬組成物

Country Status (28)

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US (3) US10206877B2 (enExample)
EP (4) EP3131582B1 (enExample)
JP (1) JP6543268B2 (enExample)
KR (1) KR102447581B1 (enExample)
CN (2) CN110840847B (enExample)
AU (2) AU2015247850B2 (enExample)
CA (1) CA2944140C (enExample)
CL (2) CL2016002600A1 (enExample)
CY (2) CY1120582T1 (enExample)
DK (3) DK3131582T3 (enExample)
ES (3) ES2675858T3 (enExample)
FI (1) FI3925607T3 (enExample)
HR (3) HRP20230709T1 (enExample)
HU (3) HUE062736T2 (enExample)
IL (3) IL303422A (enExample)
LT (3) LT3424534T (enExample)
MX (2) MX387720B (enExample)
PL (3) PL3925607T3 (enExample)
PT (3) PT3925607T (enExample)
RS (3) RS64400B9 (enExample)
RU (1) RU2744460C2 (enExample)
SG (2) SG10201913575VA (enExample)
SI (3) SI3925607T1 (enExample)
SM (3) SMT202100461T1 (enExample)
TR (1) TR201809684T4 (enExample)
UA (1) UA124567C2 (enExample)
WO (1) WO2015160787A1 (enExample)
ZA (1) ZA201606418B (enExample)

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BR112014021090B1 (pt) 2012-02-27 2023-01-24 Vertex Pharmaceuticals Incorporated Composição farmacêutica e uso de n-[2,4-bis(1,1-dimetiletil)-5-hidróxifenil]-1,4-di-hidro-4-oxoquinolina3-carboxamida na preparação da mesma
US9012496B2 (en) 2012-07-16 2015-04-21 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide and administration thereof
CA2930199C (en) 2013-11-12 2022-10-25 Vertex Pharmaceuticals Incorporated Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases
PL3925607T3 (pl) 2014-04-15 2023-10-30 Vertex Pharmaceuticals Incorporated Kompozycje farmaceutyczne do leczenia chorób, w których pośredniczy mukowiscydozowy przezbłonowy regulator przewodnictwa
MA40770B1 (fr) 2014-10-03 2021-11-30 Sanofi Sa Dérivés d'imidazoles pentacyclic fusionnés
IL313498A (en) 2014-10-06 2024-08-01 Vertex Pharma Modulators of the cystic fibrosis transmembrane conductance regulator
ES2702288T3 (es) 2014-10-07 2019-02-28 Vertex Pharma Co-cristales de moduladores de regulador de conductancia transmembrana de la fibrosis quística
SI3221692T1 (sl) 2014-11-18 2021-11-30 Vertex Pharmaceuticals Inc. Postopek za izvajanje testov visoke prepustnosti z visoko zmogljivostno tekočinsko kromatografijo
US10196384B2 (en) 2015-03-31 2019-02-05 Vertex Pharmaceuticals (Europe) Limited Deuterated CFTR modulators
CA3019380A1 (en) 2016-03-31 2017-10-05 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
HUP1600270A2 (hu) 2016-04-25 2017-10-30 Druggability Tech Ip Holdco Ltd Ivacaftornak, sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyszerészetileg elfogadott készítményei
HUP1600271A2 (hu) 2016-04-25 2017-10-30 Druggability Tech Ip Holdco Ltd Ivacaftor és Lumacaftor sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyszerészetileg elfogadható készítményei
US10383865B2 (en) 2016-04-25 2019-08-20 Druggability Technologies Ip Holdco Limited Pharmaceutical combination composition comprising complex formulations of Ivacaftor and Lumacaftor and their salts and derivatives, process for their preparation thereof and pharmaceutical compositions containing them
US10206915B2 (en) 2016-04-25 2019-02-19 Druggability Technologies Ip Holdco Limited Complexes of Ivacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them
JP7061115B2 (ja) 2016-09-30 2022-04-27 バーテックス ファーマシューティカルズ インコーポレイテッド 嚢胞性線維症膜コンダクタンス制御因子の調節因子、医薬組成物、処置の方法、及び当該調節因子を作製するためのプロセス
RS61150B1 (sr) 2016-12-09 2020-12-31 Vertex Pharma Modulator regulatora transmembranske provodljivosti cistične fibroze, farmaceutske kompozicije, postupci lečenja, i postupak za dobijanje modulatora
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US11253509B2 (en) 2017-06-08 2022-02-22 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
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US20210228489A1 (en) 2017-12-04 2021-07-29 Vertex Pharmaceuticals Incorporated Compositions for treating cystic fibrosis
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