|
US2056046A
(en)
|
1933-05-19 |
1936-09-29 |
Rhone Poulenc Sa |
Manufacture of bases derived from benz-dioxane
|
|
US2375138A
(en)
|
1942-05-01 |
1945-05-01 |
American Cyanamid Co |
Alkamine esters of aryloxymethyl benzoic acid
|
|
US2629736A
(en)
|
1951-02-24 |
1953-02-24 |
Searle & Co |
Basically substituted n-alkyl derivatives of alpha, beta, beta-triarylpropionamides
|
|
US2730544A
(en)
|
1952-07-23 |
1956-01-10 |
Sahyun Lab |
Alkylaminoalkyl esters of hydroxycyclohexylbenzoic acid
|
|
US2750387A
(en)
|
1953-11-25 |
1956-06-12 |
Searle & Co |
Basically substituted derivatives of diarylaminobenzamides
|
|
DE1211359B
(de)
|
1955-11-29 |
1966-02-24 |
Oreal |
Oxydationsmittelfreies Kaltfaerbemittel fuer menschliches Haar
|
|
US2928833A
(en)
|
1959-03-03 |
1960-03-15 |
S E Massengill Company |
Theophylline derivatives
|
|
US3174901A
(en)
|
1963-01-31 |
1965-03-23 |
Jan Marcel Didier Aron Samuel |
Process for the oral treatment of diabetes
|
|
US3454635A
(en)
|
1965-07-27 |
1969-07-08 |
Hoechst Ag |
Benzenesulfonyl-ureas and process for their manufacture
|
|
US3673241A
(en)
|
1968-04-04 |
1972-06-27 |
Ciba Geigy Corp |
Substituted benzaldehyde guanylhydrazones
|
|
ES385302A1
(es)
|
1970-10-22 |
1973-04-16 |
Miquel S A Lab |
Procedimiento para la obtencion de derivados trisubstitui- dos de etilendiamina.
|
|
NL167151C
(nl)
|
1971-04-09 |
1981-11-16 |
Acf Chemiefarma Nv |
Werkwijze ter bereiding van geneesmiddelen met anti-parasitaire werking op basis van halogeen bevatten- de 2,2'-methyleendifenolderivaten, alsmede werkwijze ter bereiding van deze geneeskrachtige verbindingen.
|
|
DE2205815A1
(de)
|
1972-02-08 |
1973-08-16 |
Hoechst Ag |
Piperazinderivate und verfahren zu ihrer herstellung
|
|
JPS5512435B2
(enExample)
|
1972-07-01 |
1980-04-02 |
|
|
|
US4005208A
(en)
|
1975-05-16 |
1977-01-25 |
Smithkline Corporation |
N-Heterocyclic-9-xanthenylamines
|
|
US4061753A
(en)
|
1976-02-06 |
1977-12-06 |
Interx Research Corporation |
Treating psoriasis with transient pro-drug forms of xanthine derivatives
|
|
NO154918C
(no)
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
DE2758025A1
(de)
|
1977-12-24 |
1979-07-12 |
Bayer Ag |
Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
|
|
DE2929596A1
(de)
|
1979-07-21 |
1981-02-05 |
Hoechst Ag |
Verfahren zur herstellung von oxoalkyl-xanthinen
|
|
DE2951135A1
(de)
|
1979-12-19 |
1981-06-25 |
Hoechst Ag, 6230 Frankfurt |
Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung
|
|
JPS5639056A
(en)
|
1980-07-16 |
1981-04-14 |
Kanebo Ltd |
Preparation of n,n,n',n'-tetraacylated nucleus halogenated aromatic diamine
|
|
CY1306A
(en)
|
1980-10-01 |
1985-12-06 |
Glaxo Group Ltd |
Aminoalkyl furan derivative
|
|
US4382091A
(en)
|
1981-04-30 |
1983-05-03 |
Syntex (U.S.A.) Inc. |
Stabilization of 1-substituted imidazole derivatives in talc
|
|
JPS58164502A
(ja)
|
1982-03-26 |
1983-09-29 |
Chugai Pharmaceut Co Ltd |
除草用組成物
|
|
FR2558162B1
(fr)
|
1984-01-17 |
1986-04-25 |
Adir |
Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
|
|
FI79107C
(fi)
|
1984-06-25 |
1989-11-10 |
Orion Yhtymae Oy |
Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.
|
|
AR240698A1
(es)
|
1985-01-19 |
1990-09-28 |
Takeda Chemical Industries Ltd |
Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
|
|
US4786755A
(en)
|
1985-06-03 |
1988-11-22 |
Warner-Lambert Company |
Diphenic acid monoamides
|
|
US4602023A
(en)
|
1985-06-03 |
1986-07-22 |
Warner-Lambert Company |
Diphenic acid monoamides
|
|
US5258380A
(en)
|
1985-06-24 |
1993-11-02 |
Janssen Pharmaceutica N.V. |
(4-piperidinylmethyl and -hetero)purines
|
|
GB8515934D0
(en)
|
1985-06-24 |
1985-07-24 |
Janssen Pharmaceutica Nv |
(4-piperidinomethyl and-hetero)purines
|
|
DE3688827T2
(de)
|
1985-10-25 |
1994-03-31 |
Beecham Group Plc |
Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
|
|
US5433959A
(en)
|
1986-02-13 |
1995-07-18 |
Takeda Chemical Industries, Ltd. |
Stabilized pharmaceutical composition
|
|
ATE72244T1
(de)
|
1986-03-21 |
1992-02-15 |
Heumann Pharma Gmbh & Co |
Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
|
|
WO1987006941A1
(en)
|
1986-05-05 |
1987-11-19 |
The General Hospital Corporation |
Insulinotropic hormone
|
|
AU619444B2
(en)
|
1986-06-02 |
1992-01-30 |
Nippon Chemiphar Co. Ltd. |
2-(2-aminobenzylsulfinyl)- benzimidazole derivatives
|
|
US4802924A
(en)
*
|
1986-06-19 |
1989-02-07 |
Colorcon, Inc. |
Coatings based on polydextrose for aqueous film coating of pharmaceutical food and confectionary products
|
|
US4968672A
(en)
|
1987-01-02 |
1990-11-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adenosine receptor prodrugs
|
|
US4743450A
(en)
|
1987-02-24 |
1988-05-10 |
Warner-Lambert Company |
Stabilized compositions
|
|
JPS6440433A
(en)
|
1987-08-05 |
1989-02-10 |
Green Cross Corp |
Aqueous liquid composition of thrombin
|
|
US4786023A
(en)
|
1987-08-19 |
1988-11-22 |
Harris Leverett D |
Drafting implement holder
|
|
EP0342675B1
(en)
|
1988-05-19 |
1995-01-25 |
Chugai Seiyaku Kabushiki Kaisha |
Novel quinolonecarboxylic acid derivatives
|
|
US5329025A
(en)
|
1988-09-21 |
1994-07-12 |
G. D. Searle & Co. |
3-azido compound
|
|
DE3926119A1
(de)
|
1989-08-08 |
1991-02-14 |
Bayer Ag |
3-amino-5-aminocarbonyl-1,2,4-triazol-derivate
|
|
US5234897A
(en)
|
1989-03-15 |
1993-08-10 |
Bayer Aktiengesellschaft |
Herbicidal 3-amino-5-aminocarbonyl-1,2,4-triazoles
|
|
GB8906792D0
(en)
|
1989-03-23 |
1989-05-10 |
Beecham Wuelfing Gmbh & Co Kg |
Treatment and compounds
|
|
DE3916430A1
(de)
|
1989-05-20 |
1990-11-22 |
Bayer Ag |
Verfahren zur herstellung von 3-amino-5-aminocarbonyl-1,2,4-triazol-derivaten
|
|
US5332744A
(en)
|
1989-05-30 |
1994-07-26 |
Merck & Co., Inc. |
Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
|
|
IL94390A
(en)
|
1989-05-30 |
1996-03-31 |
Merck & Co Inc |
The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
|
|
US5223499A
(en)
|
1989-05-30 |
1993-06-29 |
Merck & Co., Inc. |
6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
HU208115B
(en)
|
1989-10-03 |
1993-08-30 |
Biochemie Gmbh |
New process for producting pleuromutilin derivatives
|
|
FR2654935B1
(fr)
|
1989-11-28 |
1994-07-01 |
Lvmh Rech |
Utilisation de xanthines, eventuellement incorporees dans des liposomes, pour favoriser la pigmentation de la peau ou des cheveux.
|
|
IL97219A
(en)
|
1990-02-19 |
1995-12-08 |
Ciba Geigy Ag |
Biphenyl substituted aliphatic amino compounds process for their preparation and pharmaceutical compositions containing them
|
|
KR930000861B1
(ko)
|
1990-02-27 |
1993-02-08 |
한미약품공업 주식회사 |
오메프라졸 직장투여 조성물
|
|
DK0475482T3
(da)
|
1990-09-13 |
1995-04-03 |
Akzo Nobel Nv |
Stabiliserede faste kemiske midler
|
|
GB9020959D0
(en)
|
1990-09-26 |
1990-11-07 |
Beecham Group Plc |
Novel compounds
|
|
US5084460A
(en)
|
1990-12-24 |
1992-01-28 |
A. H. Robins Company, Incorporated |
Methods of therapeutic treatment with N-(3-ouinuclidinyl)-2-hydroxybenzamides and thiobenzamides
|
|
US5602127A
(en)
|
1991-02-06 |
1997-02-11 |
Karl Thomae Gmbh |
(Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
|
|
US5594003A
(en)
|
1991-02-06 |
1997-01-14 |
Dr. Karl Thomae Gmbh |
Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
|
|
US5614519A
(en)
|
1991-02-06 |
1997-03-25 |
Karl Thomae Gmbh |
(1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
|
|
GB9109862D0
(en)
|
1991-05-08 |
1991-07-03 |
Beecham Lab Sa |
Pharmaceutical formulations
|
|
DE4124150A1
(de)
|
1991-07-20 |
1993-01-21 |
Bayer Ag |
Substituierte triazole
|
|
US5300298A
(en)
|
1992-05-06 |
1994-04-05 |
The Pennsylvania Research Corporation |
Methods of treating obesity with purine related compounds
|
|
GB9215633D0
(en)
|
1992-07-23 |
1992-09-09 |
Smithkline Beecham Plc |
Novel treatment
|
|
EP0581552B1
(en)
|
1992-07-31 |
1998-04-22 |
Shionogi & Co., Ltd. |
Triazolylthiomethylthio cephalosporin hyrochloride, its crystalline hydrate and the production of the same
|
|
TW252044B
(enExample)
|
1992-08-10 |
1995-07-21 |
Boehringer Ingelheim Kg |
|
|
DE4242459A1
(de)
|
1992-12-16 |
1994-06-23 |
Merck Patent Gmbh |
Imidazopyridine
|
|
CA2118117A1
(en)
|
1993-02-18 |
1994-08-19 |
Shigeki Fujiwara |
Adenosine uptake inhibitor
|
|
FR2707641B1
(fr)
|
1993-07-16 |
1995-08-25 |
Fournier Ind & Sante |
Composés de l'imidazol-5-carboxamide, leur procédé de préparation leurs intermédiaires et leur utilisation en thérapeutique.
|
|
DE4339868A1
(de)
|
1993-11-23 |
1995-05-24 |
Merck Patent Gmbh |
Imidazopyridazine
|
|
DE4404183A1
(de)
|
1994-02-10 |
1995-08-17 |
Merck Patent Gmbh |
4-Amino-1-piperidylbenzoylguanidine
|
|
US5545745A
(en)
|
1994-05-23 |
1996-08-13 |
Sepracor, Inc. |
Enantioselective preparation of optically pure albuterol
|
|
CO4410191A1
(es)
|
1994-09-19 |
1997-01-09 |
Lilly Co Eli |
SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
|
|
EP0785927B1
(en)
|
1994-10-12 |
2003-08-27 |
Euroceltique S.A. |
Novel benzoxazoles
|
|
GB9501178D0
(en)
|
1995-01-20 |
1995-03-08 |
Wellcome Found |
Guanine derivative
|
|
EP0825993A1
(en)
|
1995-05-19 |
1998-03-04 |
Chiroscience Limited |
Xanthines and their therapeutic use
|
|
GB9523752D0
(en)
|
1995-11-21 |
1996-01-24 |
Pfizer Ltd |
Pharmaceutical formulations
|
|
DE19543478A1
(de)
|
1995-11-22 |
1997-05-28 |
Bayer Ag |
Kristallines Hydrochlorid von {(R)-(-)-2- N-[4-(1,1-Dioxido-3-oxo-2,3-dihydrobenzisothiazol-2-yl)-buytl]-aminomethyl}-chroman
|
|
FR2742751B1
(fr)
|
1995-12-22 |
1998-01-30 |
Rhone Poulenc Rorer Sa |
Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
ATE215068T1
(de)
|
1995-12-26 |
2002-04-15 |
Alteon Inc |
N-acylaminoalkylhydrazinecarboximidamide
|
|
DE19616486C5
(de)
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
|
US5965555A
(en)
|
1996-06-07 |
1999-10-12 |
Hoechst Aktiengesellschaft |
Xanthine compounds having terminally animated alkynol side chains
|
|
AU1153097A
(en)
|
1996-06-07 |
1998-01-05 |
Eisai Co. Ltd. |
Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production
|
|
US5958951A
(en)
|
1996-06-14 |
1999-09-28 |
Novo Nordiskials |
Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride
|
|
US5753635A
(en)
|
1996-08-16 |
1998-05-19 |
Berlex Laboratories, Inc. |
Purine derivatives and their use as anti-coagulants
|
|
AU720366B2
(en)
|
1996-09-23 |
2000-06-01 |
Eli Lilly And Company |
Olanzapine dihydrate D
|
|
EP0937056A1
(en)
|
1996-10-28 |
1999-08-25 |
Novo Nordisk A/S |
A process for the preparation of (-)-3,4-trans-diarylchromans
|
|
UA65549C2
(uk)
|
1996-11-05 |
2004-04-15 |
Елі Ліллі Енд Компані |
Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
|
|
EP0941114B1
(en)
|
1996-11-12 |
2005-02-23 |
Novo Nordisk A/S |
Use of glp-1 peptides
|
|
GB9623859D0
(en)
|
1996-11-15 |
1997-01-08 |
Chiroscience Ltd |
Novel compounds
|
|
TR199901968T2
(xx)
|
1996-12-24 |
1999-12-21 |
Biogen, Inc. |
Sabit s�v� interferon form�lleri.
|
|
WO1998030341A1
(en)
*
|
1997-01-06 |
1998-07-16 |
Berwind Pharmaceutical Services, Inc. |
Film coatings and film coating compositions based on dextrin
|
|
WO1998031697A1
(en)
|
1997-01-15 |
1998-07-23 |
Sankyo Company, Limited |
Aryl c-glycoside compounds and sulfated esters thereof
|
|
DE19705233A1
(de)
|
1997-02-12 |
1998-08-13 |
Froelich Juergen C |
Verfahren zur Herstellung einer Formulierung enthaltend Arginin
|
|
US6011049A
(en)
|
1997-02-19 |
2000-01-04 |
Warner-Lambert Company |
Combinations for diabetes
|
|
JP4608031B2
(ja)
|
1997-03-13 |
2011-01-05 |
ヘキサル アーゲー |
アミノ酸／シクロデキストリン混合物による酸感受性ベンズイミダゾール類の安定化
|
|
US5972332A
(en)
|
1997-04-16 |
1999-10-26 |
The Regents Of The University Of Michigan |
Wound treatment with keratinocytes on a solid support enclosed in a porous material
|
|
US6635280B2
(en)
|
1997-06-06 |
2003-10-21 |
Depomed, Inc. |
Extending the duration of drug release within the stomach during the fed mode
|
|
EP0998271B3
(en)
|
1997-06-06 |
2014-10-29 |
Depomed, Inc. |
Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
|
|
AR012894A1
(es)
|
1997-06-13 |
2000-11-22 |
Lilly Co Eli |
Formulacion de insulina en solucion estable, su uso para preparar un medicamento y proceso para la preparacion de la misma.
|
|
JPH11124392A
(ja)
|
1997-10-21 |
1999-05-11 |
Sankyo Co Ltd |
Ｃ−グリコシル化されたアリールスズ化合物
|
|
IL136499A0
(en)
|
1997-12-05 |
2001-06-14 |
Astrazeneca Uk Ltd Astrazeneca |
Pyrrolo-, thieno-, furano- and pyrazolo-[3,4,d] pypyrrolo-, thieno-, furano- and pyrazolo-[3,4,d] pyridazinone compounds, process for their preparatioridaziones compounds, process for their preparation, pharmaceutical compositions containing them, a n, pharmaceutical compositions containing them, a process for prepating the pharmaceutical compositiprocess for preparing the pharmaceutical compositions, and use thereof ons, and use thereof
|
|
TW589174B
(en)
|
1997-12-10 |
2004-06-01 |
Takeda Chemical Industries Ltd |
Agent for treating high-risk impaired glucose tolerance
|
|
JPH11193270A
(ja)
|
1997-12-26 |
1999-07-21 |
Koei Chem Co Ltd |
光学活性１−メチル−３−ピペリジンメタノールの製造方法
|
|
EP1054012B1
(en)
|
1998-01-05 |
2003-06-11 |
Eisai Co., Ltd. |
Purine derivatives and adenosine a2 receptor antagonists serving as preventives/remedies for diabetes
|
|
US6803357B1
(en)
|
1998-02-02 |
2004-10-12 |
New England Medical Center Hospitals, Inc. |
Method of regulating glucose metabolism, and reagents related thereto
|
|
CA2320900C
(en)
|
1998-03-19 |
2009-10-27 |
Bristol-Myers Squibb Company |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method
|
|
US6099859A
(en)
|
1998-03-20 |
2000-08-08 |
Andrx Pharmaceuticals, Inc. |
Controlled release oral tablet having a unitary core
|
|
WO1999050248A1
(en)
|
1998-03-31 |
1999-10-07 |
Nissan Chemical Industries, Ltd. |
Pyridazinone hydrochloride compound and method for producing the same
|
|
CA2268621A1
(en)
|
1998-04-13 |
1999-10-13 |
Takeda Chemical Industries, Ltd. |
2-pipirazinone-1-acetic acid derivative, production and use thereof
|
|
US6207207B1
(en)
|
1998-05-01 |
2001-03-27 |
Mars, Incorporated |
Coated confectionery having a crispy starch based center and method of preparation
|
|
DE19823831A1
(de)
|
1998-05-28 |
1999-12-02 |
Probiodrug Ges Fuer Arzneim |
Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
|
|
DE19828114A1
(de)
|
1998-06-24 |
2000-01-27 |
Probiodrug Ges Fuer Arzneim |
Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
|
|
CO5150173A1
(es)
|
1998-12-10 |
2002-04-29 |
Novartis Ag |
Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
|
|
US6613806B1
(en)
|
1999-01-29 |
2003-09-02 |
Basf Corporation |
Enhancement of the efficacy of benzoylbenzenes
|
|
IT1312018B1
(it)
|
1999-03-19 |
2002-04-04 |
Fassi Aldo |
Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina.
|
|
US20040152659A1
(en)
|
1999-05-12 |
2004-08-05 |
Fujisawa Pharmaceutical Co. Ltd. |
Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist
|
|
AU4431000A
(en)
|
1999-05-12 |
2000-12-05 |
Fujisawa Pharmaceutical Co., Ltd. |
Novel use
|
|
AU5294100A
(en)
|
1999-05-27 |
2000-12-18 |
University Of Virginia Patent Foundation |
Method and compositions for treating the inflammatory response
|
|
US6545002B1
(en)
|
1999-06-01 |
2003-04-08 |
University Of Virginia Patent Foundation |
Substituted 8-phenylxanthines useful as antagonists of A2B adenosine receptors
|
|
WO2000078735A1
(de)
|
1999-06-21 |
2000-12-28 |
Boehringer Ingelheim Pharma Kg |
Bicyclische heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
|
US6448323B1
(en)
*
|
1999-07-09 |
2002-09-10 |
Bpsi Holdings, Inc. |
Film coatings and film coating compositions based on polyvinyl alcohol
|
|
ES2166270B1
(es)
|
1999-07-27 |
2003-04-01 |
Almirall Prodesfarma Sa |
Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona.
|
|
CN1145635C
(zh)
|
1999-08-31 |
2004-04-14 |
橘生药品工业株式会社 |
吡喃葡糖氧基吡唑衍生物、含该衍生物的药物组合物及其制备中的中间体
|
|
US6515117B2
(en)
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
PH12000002657B1
(en)
|
1999-10-12 |
2006-02-21 |
Bristol Myers Squibb Co |
C-aryl glucoside SGLT2 inhibitors
|
|
US6586438B2
(en)
|
1999-11-03 |
2003-07-01 |
Bristol-Myers Squibb Co. |
Antidiabetic formulation and method
|
|
GB9928330D0
(en)
|
1999-11-30 |
2000-01-26 |
Ferring Bv |
Novel antidiabetic agents
|
|
SK8902002A3
(en)
|
1999-12-23 |
2002-11-06 |
Novartis Ag |
Use of hypoglycemic agent for treating impaired glucose metabolism
|
|
SK9742002A3
(en)
|
2000-01-07 |
2003-02-04 |
Transform Pharmaceuticals Inc |
High-throughput formation, identification, and analysis of diverse solid-forms
|
|
US6362172B2
(en)
|
2000-01-20 |
2002-03-26 |
Bristol-Myers Squibb Company |
Water soluble prodrugs of azole compounds
|
|
ES2487897T3
(es)
|
2000-01-21 |
2014-08-25 |
Novartis Ag |
Combinaciones que consisten de inhibidores de la dipeptidilpeptidasa-IV y agentes antidiabéticos
|
|
JP4621326B2
(ja)
|
2000-02-01 |
2011-01-26 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
テプレノンの安定化組成物
|
|
JP4456768B2
(ja)
|
2000-02-02 |
2010-04-28 |
壽製薬株式会社 |
Ｃ−配糖体を含有する薬剤
|
|
US6627611B2
(en)
|
2000-02-02 |
2003-09-30 |
Kotobuki Pharmaceutical Co Ltd |
C-glycosides and preparation of thereof as antidiabetic agents
|
|
CA2369076A1
(en)
|
2000-02-05 |
2001-08-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compositions useful as inhibitors of erk
|
|
CA2401356A1
(en)
|
2000-02-24 |
2001-08-30 |
Takeda Chemical Industries, Ltd. |
Combination drug
|
|
EP1132389A1
(en)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
New aza-indolyl derivatives for the treatment of obesity
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
GB0006133D0
(en)
|
2000-03-14 |
2000-05-03 |
Smithkline Beecham Plc |
Novel pharmaceutical
|
|
US20010053791A1
(en)
*
|
2000-03-16 |
2001-12-20 |
Babcock Walter C. |
Glycogen phosphorylase inhibitor
|
|
JP2001278812A
(ja)
|
2000-03-27 |
2001-10-10 |
Kyoto Pharmaceutical Industries Ltd |
錠剤用崩壊剤及びこれを用いた錠剤
|
|
US6683056B2
(en)
|
2000-03-30 |
2004-01-27 |
Bristol-Myers Squibb Company |
O-aryl glucoside SGLT2 inhibitors and method
|
|
DK1283735T4
(da)
|
2000-03-31 |
2013-02-04 |
Royalty Pharma Collection Trust |
Fremgangsmåde til forbedring signalering af øceller ved diabetes mellitus og til forebyggelse deraf
|
|
JP2001292388A
(ja)
|
2000-04-05 |
2001-10-19 |
Sharp Corp |
再生装置
|
|
GB0008694D0
(en)
|
2000-04-07 |
2000-05-31 |
Novartis Ag |
Organic compounds
|
|
US6962998B2
(en)
|
2000-06-14 |
2005-11-08 |
Toray Industries, Inc. |
Processes for producing racemic piperidine derivative and for producing optically active piperidine derivative
|
|
US7078397B2
(en)
|
2000-06-19 |
2006-07-18 |
Smithkline Beecham Corporation |
Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
|
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
|
US6488962B1
(en)
|
2000-06-20 |
2002-12-03 |
Depomed, Inc. |
Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
|
|
HUP0301622A3
(en)
|
2000-07-04 |
2006-05-29 |
Novo Nordisk As |
Purine derivatives inhibiting the enzyme dipeptidyl petidase iv (dpp-iv) and pharmaceutical compositions containing them
|
|
DE60140708D1
(de)
|
2000-08-10 |
2010-01-14 |
Mitsubishi Tanabe Pharma Corp |
Prolinderivative und deren Verwendung als Medikamente
|
|
US6821978B2
(en)
|
2000-09-19 |
2004-11-23 |
Schering Corporation |
Xanthine phosphodiesterase V inhibitors
|
|
CZ303544B6
(cs)
|
2000-09-29 |
2012-11-28 |
Kissei Pharmaceutical Co., Ltd. |
Glukopyranosyloxybenzylbenzenový derivát a farmaceutická kompozice s jeho obsahem
|
|
US6866866B1
(en)
|
2000-11-03 |
2005-03-15 |
Andrx Labs, Llc |
Controlled release metformin compositions
|
|
US20060034922A1
(en)
|
2000-11-03 |
2006-02-16 |
Andrx Labs, Llc |
Controlled release metformin compositions
|
|
US6790459B1
(en)
|
2000-11-03 |
2004-09-14 |
Andrx Labs, Llc |
Methods for treating diabetes via administration of controlled release metformin
|
|
CA2429833A1
(en)
|
2000-11-30 |
2002-06-06 |
Kissei Pharmaceutical Co., Ltd. |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
|
|
US20040180925A1
(en)
|
2000-12-27 |
2004-09-16 |
Kenji Matsuno |
Dipeptidylpeptidase-IV inhibitor
|
|
HU228915B1
(en)
|
2000-12-28 |
2013-06-28 |
Kissei Pharmaceutical |
Glucopyranosyloxypyrazole derivatives and use thereof
|
|
FR2819254B1
(fr)
|
2001-01-08 |
2003-04-18 |
Fournier Lab Sa |
Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques
|
|
DE10117803A1
(de)
|
2001-04-10 |
2002-10-24 |
Boehringer Ingelheim Pharma |
Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE10109021A1
(de)
|
2001-02-24 |
2002-09-05 |
Boehringer Ingelheim Pharma |
Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
BR0206831A
(pt)
|
2001-02-02 |
2004-07-06 |
Takeda Chemical Industries Ltd |
Composto, cristal, agente farmacêutico, agentes para profilaxia ou tratamento de diabetes, de complicações diabéticas, de tolerância prejudicada à glucose e de obesidade, inibidor de peptidase, uso de um composto, e, método de produção de um composto
|
|
TWI255817B
(en)
|
2001-02-14 |
2006-06-01 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
|
|
WO2002066015A1
(en)
|
2001-02-16 |
2002-08-29 |
Bristol-Myers Squibb Pharma Company |
Use of polyalkylamine polymers in controlled release devices
|
|
SK286975B6
(sk)
|
2001-02-24 |
2009-08-06 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xantínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
|
|
US6936590B2
(en)
|
2001-03-13 |
2005-08-30 |
Bristol Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
US6693094B2
(en)
|
2001-03-22 |
2004-02-17 |
Chrono Rx Llc |
Biguanide and sulfonylurea formulations for the prevention and treatment of insulin resistance and type 2 diabetes mellitus
|
|
JP3698067B2
(ja)
|
2001-03-30 |
2005-09-21 |
Ｊｓｒ株式会社 |
電子吸引性基および電子供与性基を有するモノマー、それを用いた共重合体、ならびにプロトン伝導膜
|
|
CA2444481A1
(en)
|
2001-04-11 |
2002-10-24 |
Bristol-Myers Squibb Company |
Amino acid complexes of c-aryl glucosides for treatment of diabetes and method
|
|
JP2002348279A
(ja)
|
2001-05-25 |
2002-12-04 |
Nippon Kayaku Co Ltd |
光学活性ピリジルケトン誘導体の製造方法並びに光学活性ピリジルケトン誘導体
|
|
DE10130371A1
(de)
|
2001-06-23 |
2003-01-02 |
Boehringer Ingelheim Pharma |
Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
|
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
|
US7183290B2
(en)
|
2001-06-27 |
2007-02-27 |
Smithkline Beecham Corporation |
Fluoropyrrolidines as dipeptidyl peptidase inhibitors
|
|
DE60222667T2
(de)
|
2001-06-27 |
2008-07-17 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren
|
|
US6869947B2
(en)
|
2001-07-03 |
2005-03-22 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
|
DE60225556D1
(de)
|
2001-07-03 |
2008-04-24 |
Novo Nordisk As |
Dpp-iv-inhibierende purin-derivative zur behandlung von diabetes
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
US7638522B2
(en)
|
2001-08-13 |
2009-12-29 |
Janssen Pharmaceutica N.V. |
Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
|
|
WO2003020737A1
(en)
|
2001-09-05 |
2003-03-13 |
Bristol-Myers Squibb Company |
O-pyrazole glucoside sglt2 inhibitors and method of use
|
|
JP2005509603A
(ja)
|
2001-09-19 |
2005-04-14 |
ノボ ノルディスク アクティーゼルスカブ |
Ｄｐｐ−ｉｖ酵素の阻害剤であるヘテロ環化合物
|
|
WO2003031458A1
(en)
|
2001-10-12 |
2003-04-17 |
Dana-Farber Cancer Institute |
Methods for synthesis of diarylmethanes
|
|
BR0213279A
(pt)
|
2001-10-15 |
2004-10-26 |
Hemoteq Gmbh |
Revestimento de stents para impedir a restenose
|
|
ES2314106T3
(es)
|
2001-10-17 |
2009-03-16 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG |
Derivados de pirimidina, agentes farmaceuticos que contiene dichos compuestos, uso y metodo para su obtencion.
|
|
DE10151296A1
(de)
|
2001-10-17 |
2003-04-30 |
Boehringer Ingelheim Pharma |
Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden
|
|
US6723340B2
(en)
*
|
2001-10-25 |
2004-04-20 |
Depomed, Inc. |
Optimal polymer mixtures for gastric retentive tablets
|
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
|
US20030083354A1
(en)
|
2001-10-26 |
2003-05-01 |
Pediamed Pharmaceuticals, Inc. |
Phenylephrine tannate and pyrilamine tannate salts in pharmaceutical compositions
|
|
CA2363053C
(en)
|
2001-11-09 |
2011-01-25 |
Bernard Charles Sherman |
Clopidogrel bisulfate tablet formulation
|
|
EP1457487A4
(en)
|
2001-12-21 |
2005-06-22 |
Toray Finechemicals Co Ltd |
PROCESS FOR PREPARING OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES
|
|
US6727261B2
(en)
|
2001-12-27 |
2004-04-27 |
Hoffman-La Roche Inc. |
Pyrido[2,1-A]Isoquinoline derivatives
|
|
WO2003057200A2
(en)
|
2002-01-11 |
2003-07-17 |
Novo Nordisk A/S |
Compositions comprising inhibitors of dpp-iv and nep enzymes for the treatment of diabetes
|
|
ES2445041T3
(es)
|
2002-01-16 |
2014-02-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Método para la preparación de telmisartán amorfo
|
|
EP1333033A1
(en)
|
2002-01-30 |
2003-08-06 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
FAP-activated anti-tumor compounds
|
|
BR0307516A
(pt)
|
2002-02-01 |
2004-12-07 |
Pfizer Prod Inc |
Formas de dosagem de liberação imediata contendo dispersões de uma droga sólida
|
|
US7610153B2
(en)
|
2002-02-13 |
2009-10-27 |
Virginia Commonwealth University |
Multi-drug titration and evaluation
|
|
ES2377729T3
(es)
*
|
2002-02-21 |
2012-03-30 |
Valeant International (Barbados) Srl |
Formulaciones de liberación modificada de al menos una forma de tramadol
|
|
US7074798B2
(en)
|
2002-02-25 |
2006-07-11 |
Eisai Co., Ltd |
Xanthine derivative and DPPIV inhibitor
|
|
HUP0200849A2
(hu)
|
2002-03-06 |
2004-08-30 |
Sanofi-Synthelabo |
N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
|
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
|
JP4298212B2
(ja)
|
2002-03-29 |
2009-07-15 |
大日本印刷株式会社 |
塩酸エピナスチン高融点型結晶の製造法
|
|
JP2003300977A
(ja)
|
2002-04-10 |
2003-10-21 |
Sumitomo Pharmaceut Co Ltd |
キサンチン誘導体
|
|
WO2003088900A2
(en)
|
2002-04-16 |
2003-10-30 |
Merck & Co., Inc. |
Solid forms of salts with tyrosine kinase activity
|
|
EP1500403A4
(en)
|
2002-04-26 |
2008-09-17 |
Ajinomoto Kk |
MEANS FOR THE PREVENTION / TREATMENT OF DIABETES
|
|
AU2003231252A1
(en)
|
2002-05-09 |
2003-11-11 |
Enos Pharmaceuticals, Inc. |
Methods and compositions for the treatment and prevention of intermittent claudication or alzheimer's disease
|
|
GB0212412D0
(en)
|
2002-05-29 |
2002-07-10 |
Novartis Ag |
Combination of organic compounds
|
|
US7074923B2
(en)
|
2002-05-31 |
2006-07-11 |
Schering Corporation |
Process for preparing xanthine phosphodiesterase V inhibitors and precursors thereof
|
|
CN100348599C
(zh)
|
2002-06-06 |
2007-11-14 |
卫材R&D管理有限公司 |
新的稠合咪唑衍生物
|
|
FR2840897B1
(fr)
|
2002-06-14 |
2004-09-10 |
Fournier Lab Sa |
Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique
|
|
US20040002615A1
(en)
|
2002-06-28 |
2004-01-01 |
Allen David Robert |
Preparation of chiral amino-nitriles
|
|
DE10231370B4
(de)
|
2002-07-11 |
2006-04-06 |
Sanofi-Aventis Deutschland Gmbh |
Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
|
US20040023981A1
(en)
|
2002-07-24 |
2004-02-05 |
Yu Ren |
Salt forms with tyrosine kinase activity
|
|
TW200409746A
(en)
|
2002-07-26 |
2004-06-16 |
Theravance Inc |
Crystalline β2 adrenergic receptor agonist
|
|
TWI254635B
(en)
|
2002-08-05 |
2006-05-11 |
Yamanouchi Pharma Co Ltd |
Azulene derivative and salt thereof
|
|
AU2003254847B2
(en)
|
2002-08-08 |
2009-06-04 |
Kissei Pharmaceutical Co., Ltd. |
Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof
|
|
TW200404796A
(en)
|
2002-08-19 |
2004-04-01 |
Ono Pharmaceutical Co |
Nitrogen-containing compound
|
|
EP1532149B9
(de)
|
2002-08-21 |
2011-04-20 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
8-[3-amino-piperidin-1-yl] -xanthine, deren herstellung und deren verwendung als arzneimittel
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10238243A1
(de)
|
2002-08-21 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
|
DE10238477A1
(de)
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Purinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE10238470A1
(de)
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7569574B2
(en)
|
2002-08-22 |
2009-08-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10238723A1
(de)
|
2002-08-23 |
2004-03-11 |
Bayer Ag |
Phenyl-substituierte Pyrazolyprimidine
|
|
DE10238724A1
(de)
|
2002-08-23 |
2004-03-04 |
Bayer Ag |
Alkyl-substituierte Pyrazolpyrimidine
|
|
EP1537880A4
(en)
|
2002-09-11 |
2009-07-01 |
Takeda Pharmaceutical |
Sustained release preparation
|
|
CA2498931A1
(en)
|
2002-09-16 |
2004-03-25 |
Wyeth |
Delayed release formulations for oral administration of a polypeptide therapeutic agent and methods of using same
|
|
US20060094722A1
(en)
|
2002-09-26 |
2006-05-04 |
Eisai Co., Ltd. |
Combination drug
|
|
US20040122048A1
(en)
|
2002-10-11 |
2004-06-24 |
Wyeth Holdings Corporation |
Stabilized pharmaceutical composition containing basic excipients
|
|
US6861526B2
(en)
|
2002-10-16 |
2005-03-01 |
Pfizer Inc. |
Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
|
|
RU2301803C2
(ru)
|
2002-10-18 |
2007-06-27 |
Мерк Энд Ко., Инк. |
Производные гексагидродиазепинона, фармацевтическая композиция, их содержащая, и применение для получения лекарственного средства для лечения инсулиннезависимого диабета
|
|
JP2004161749A
(ja)
|
2002-10-24 |
2004-06-10 |
Toray Fine Chemicals Co Ltd |
光学活性含窒素化合物の製造方法
|
|
WO2004048379A1
(ja)
|
2002-11-01 |
2004-06-10 |
Sumitomo Pharmaceuticals Co., Ltd. |
キサンチン化合物
|
|
CA2504735C
(en)
|
2002-11-07 |
2009-06-23 |
Merck & Co., Inc. |
Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10251927A1
(de)
|
2002-11-08 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
AR042095A1
(es)
|
2002-11-20 |
2005-06-08 |
Japan Tobacco Inc |
Compuesto 4-oxoquinolina y aplicacion del mismo como inhibidor de integrasa de vih
|
|
JP3567162B1
(ja)
|
2002-11-20 |
2004-09-22 |
日本たばこ産業株式会社 |
４−オキソキノリン化合物及びそのｈｉｖインテグラーゼ阻害剤としての利用
|
|
DE10254304A1
(de)
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7109192B2
(en)
|
2002-12-03 |
2006-09-19 |
Boehringer Ingelheim Pharma Gmbh & Co Kg |
Substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions
|
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
|
JP4651934B2
(ja)
|
2002-12-04 |
2011-03-16 |
キッセイ薬品工業株式会社 |
ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途
|
|
ATE404191T1
(de)
|
2002-12-10 |
2008-08-15 |
Novartis Pharma Ag |
Kombinationen von einem dpp-iv inhibitor und einem ppar- alpha agonist
|
|
DE10258008B4
(de)
|
2002-12-12 |
2006-02-02 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
|
DE10258007B4
(de)
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
|
US20040152720A1
(en)
|
2002-12-20 |
2004-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Powdered medicaments containing a tiotropium salt and salmeterol xinafoate
|
|
UA83813C2
(ru)
|
2002-12-20 |
2008-08-26 |
Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг |
Порошковое лекарственное средство, которое содержит соль тиотропия и ксинафоат салметерола
|
|
CN101260130A
(zh)
|
2003-01-03 |
2008-09-10 |
布里斯托尔-迈尔斯斯奎布公司 |
制备c-芳基葡糖苷sglt2抑制剂的方法
|
|
WO2004062689A1
(en)
|
2003-01-08 |
2004-07-29 |
Chiron Corporation |
Stabilized aqueous compositions comprising tissue factor pathway inhibitor (tfpi) or tissue factor pathway inhibitor variant
|
|
HRP20050696B1
(en)
|
2003-01-14 |
2008-10-31 |
Arena Pharmaceuticals Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
DE10335027A1
(de)
|
2003-07-31 |
2005-02-17 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verwendung von Angiotensin II Rezeptor Antagonisten
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
JP2004250336A
(ja)
|
2003-02-18 |
2004-09-09 |
Kao Corp |
コーティング錠及び糖衣錠の製造法
|
|
US7164015B2
(en)
|
2003-02-27 |
2007-01-16 |
Bristol-Myers Squibb Company |
Non-cryogenic process for forming glycosides
|
|
US7135575B2
(en)
|
2003-03-03 |
2006-11-14 |
Array Biopharma, Inc. |
P38 inhibitors and methods of use thereof
|
|
US7442387B2
(en)
|
2003-03-06 |
2008-10-28 |
Astellas Pharma Inc. |
Pharmaceutical composition for controlled release of active substances and manufacturing method thereof
|
|
CA2515289A1
(en)
|
2003-03-12 |
2004-09-23 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Weak base salts
|
|
ES2567571T3
(es)
|
2003-03-14 |
2016-04-25 |
Astellas Pharma Inc. |
Derivados de C-glucósido y sales de los mismos
|
|
PL377614A1
(pl)
|
2003-03-18 |
2006-02-06 |
Novartis Ag |
Kompozycje zawierające kwasy tłuszczowe i aminokwasy
|
|
US20040220186A1
(en)
|
2003-04-30 |
2004-11-04 |
Pfizer Inc. |
PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
|
|
JPWO2004096806A1
(ja)
|
2003-04-30 |
2006-07-13 |
大日本住友製薬株式会社 |
縮合イミダゾール誘導体
|
|
US7674486B2
(en)
|
2003-05-14 |
2010-03-09 |
Indus Biotech Pvt. Ltd. |
Synergistic composition for the treatment of diabetes mellitus
|
|
TW200510277A
(en)
|
2003-05-27 |
2005-03-16 |
Theravance Inc |
Crystalline form of β2-adrenergic receptor agonist
|
|
EP1664073A2
(en)
|
2003-06-03 |
2006-06-07 |
The Regents of the University of California |
Compositions and methods for treatment of disease with acetylated disaccharides
|
|
AU2003902828A0
(en)
|
2003-06-05 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
JP2004359630A
(ja)
|
2003-06-06 |
2004-12-24 |
Yamanouchi Pharmaceut Co Ltd |
ジフルオロジフェニルメタン誘導体及びその塩
|
|
DE10327439A1
(de)
|
2003-06-18 |
2005-01-05 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazopyridazinon- und Imidazopyridonderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7566707B2
(en)
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
BRPI0411713B8
(pt)
|
2003-06-20 |
2021-05-25 |
Hoffmann La Roche |
compostos, processo para a sua manufatura, composições farmacêuticas que compreendem os mesmos, método para tratamento e/ou profilaxia de enfermidades que estão associadas com dpp-iv e sua utilização
|
|
RU2339636C2
(ru)
|
2003-06-20 |
2008-11-27 |
Ф.Хоффманн-Ля Рош Аг |
Гексагидропиридоизохинолины в качестве ингибиторов дипептидилпептидазы iv (dpp-iv)
|
|
JO2625B1
(en)
|
2003-06-24 |
2011-11-01 |
ميرك شارب اند دوم كوربوريشن |
Phosphoric acid salts of dipeptidyl betidase inhibitor 4
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
US7132426B2
(en)
|
2003-07-14 |
2006-11-07 |
Arena Pharmaceuticals, Inc. |
Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
|
|
US20050013863A1
(en)
*
|
2003-07-18 |
2005-01-20 |
Depomed, Inc., A Corporation Of The State Of California |
Dual drug dosage forms with improved separation of drugs
|
|
AU2003249492A1
(en)
|
2003-07-24 |
2005-02-14 |
Eswaran Krishnan Iyer |
Oral compositions for treatment of diseases
|
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
CN1829709A
(zh)
|
2003-08-01 |
2006-09-06 |
健亚生物科技公司 |
对抗黄病毒的双环咪唑衍生物
|
|
CA2549015A1
(en)
|
2003-08-01 |
2005-02-10 |
Janssen Pharmaceutica N.V. |
Substituted fused heterocyclic c-glycosides
|
|
EP2514756B1
(en)
|
2003-08-01 |
2014-12-17 |
Mitsubishi Tanabe Pharma Corporation |
Novel compounds having inhibitory activity against sodium-dependant glucose transporter
|
|
JP4131216B2
(ja)
|
2003-08-20 |
2008-08-13 |
Ｊｓｒ株式会社 |
ポリアリーレンおよびその製造方法、ならびに高分子固体電解質およびプロトン伝導膜
|
|
US7375090B2
(en)
|
2003-08-26 |
2008-05-20 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
|
|
DE502004008951D1
(de)
|
2003-08-26 |
2009-03-19 |
Boehringer Ingelheim Pharma |
Glucopyranosyloxy-pyrazole, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
|
CN1964714B
(zh)
|
2003-08-29 |
2011-09-28 |
Hdac默克研究有限责任公司 |
辛二酰苯胺异羟肟酸和吉西他滨在制备用于治疗癌症的药物中的用途
|
|
WO2005026148A1
(en)
|
2003-09-08 |
2005-03-24 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
|
US20070072810A1
(en)
|
2003-10-03 |
2007-03-29 |
Takeda Pharmaceutical Company, Limited |
Agent for treating diabetes
|
|
US20050085680A1
(en)
|
2003-10-21 |
2005-04-21 |
Joseph Auerbach |
Method for industrial decontamination
|
|
KR20120008093A
(ko)
|
2003-11-17 |
2012-01-25 |
노파르티스 아게 |
디펩티딜 펩티다제 ⅳ 억제제의 용도
|
|
DE10355304A1
(de)
|
2003-11-27 |
2005-06-23 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
JPWO2005053695A1
(ja)
|
2003-12-04 |
2007-12-06 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
多発性硬化症予防剤または治療剤
|
|
DE10359098A1
(de)
|
2003-12-17 |
2005-07-28 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 2-(Piperazin-1-yl)- und 2-([1,4]Diazepan-1-yl)-imidazo[4,5-d]pyridazin-4-one, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7217711B2
(en)
|
2003-12-17 |
2007-05-15 |
Boehringer Ingelheim International Gmbh |
Piperazin-1-yl and 2-([1,4]diazepan-1-yl)-imidazo[4,5-d]-pyridazin-4-ones, the preparation thereof and their use as pharmaceutical compositions
|
|
ATE501135T1
(de)
|
2003-12-18 |
2011-03-15 |
Tibotec Pharm Ltd |
Piperidinamino-benzimidazol-derivate al respiratorisches syncytialvirus replikation inhibitoren
|
|
DE10361133A1
(de)
|
2003-12-22 |
2005-07-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Glucopyranosyloxy-substituierte Aromaten, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
US7371732B2
(en)
|
2003-12-22 |
2008-05-13 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture
|
|
DE10360835A1
(de)
|
2003-12-23 |
2005-07-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Bicyclische Imidazolverbindungen, deren Herstellung und deren Verwendung als Arzneimittel
|
|
NZ547965A
(en)
|
2003-12-24 |
2009-12-24 |
Prosidion Ltd |
1,2,4-Oxadiazole derivatives as GPCR receptor agonists
|
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
|
CN102199151A
(zh)
|
2004-02-18 |
2011-09-28 |
贝林格尔.英格海姆国际有限公司 |
8-[3-氨基-哌啶-1-基]-黄嘌呤、制备及用途
|
|
DE102004019540A1
(de)
|
2004-04-22 |
2005-11-10 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen
|
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
|
RU2387663C2
(ru)
|
2004-03-04 |
2010-04-27 |
Киссеи Фармасьютикал Ко., Лтд. |
Конденсированные гетероциклические производные, содержащие их медицинские композиции и их медицинское применение
|
|
EP1721904A4
(en)
|
2004-03-04 |
2010-07-14 |
Kissei Pharmaceutical |
HETEROCYCLIC DERIVED FADE; MEDICAL COMPOSITION CONTAINING THE DERIVATIVE AND MEDICAL USE
|
|
EP1593671A1
(en)
|
2004-03-05 |
2005-11-09 |
Graffinity Pharmaceuticals AG |
DPP-IV inhibitors
|
|
US7393847B2
(en)
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
CN102127057A
(zh)
|
2004-03-15 |
2011-07-20 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
|
PL1730131T3
(pl)
|
2004-03-16 |
2012-10-31 |
Boehringer Ingelheim Int |
Glukopiranozylo-podstawione pochodne benzenu, środki lecznicze zawierające te związki, ich zastosowanie i sposób ich wytwarzania
|
|
EP1577306A1
(de)
|
2004-03-17 |
2005-09-21 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Neue Benzoxazinonderivate als langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
|
|
EP1740589A1
(de)
|
2004-04-10 |
2007-01-10 |
Boehringer Ingelheim International GmbH |
Neue 2-amino-imidazo[4,5-d]pyridazin-4-one und 2-amino-imidazo[4,5-c]pyridin-4-one, deren herstellung und deren verwendung als arzneimittel
|
|
US7179809B2
(en)
|
2004-04-10 |
2007-02-20 |
Boehringer Ingelheim International Gmbh |
2-Amino-imidazo[4,5-d]pyridazin-4-ones, their preparation and their use as pharmaceutical compositions
|
|
US20050239778A1
(en)
|
2004-04-22 |
2005-10-27 |
Boehringer Ingelheim International Gmbh |
Novel medicament combinations for the treatment of respiratory diseases
|
|
US20050244502A1
(en)
|
2004-04-28 |
2005-11-03 |
Mathias Neil R |
Composition for enhancing absorption of a drug and method
|
|
US7439370B2
(en)
|
2004-05-10 |
2008-10-21 |
Boehringer Ingelheim International Gmbh |
Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
|
|
PT1753748E
(pt)
|
2004-05-12 |
2009-08-28 |
Pfizer Prod Inc |
Derivados de prolina e a sua utilização como inibidores de dipeptidil peptidase iv
|
|
DE102004024454A1
(de)
|
2004-05-14 |
2005-12-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
PE20060315A1
(es)
|
2004-05-24 |
2006-05-15 |
Irm Llc |
Compuestos de tiazol como moduladores de ppar
|
|
TWI415635B
(zh)
|
2004-05-28 |
2013-11-21 |
必治妥施貴寶公司 |
加衣錠片調製物及製備彼之方法
|
|
EP1750750B1
(en)
|
2004-06-01 |
2012-02-01 |
Ares Trading S.A. |
Method of stabilizing proteins
|
|
US7935723B2
(en)
|
2004-06-04 |
2011-05-03 |
Novartis Pharma Ag |
Use of organic compounds
|
|
US20050276794A1
(en)
|
2004-06-09 |
2005-12-15 |
Papas Klearchos K |
Composition and method for improving pancreatic islet cell survival
|
|
DE102004030502A1
(de)
|
2004-06-24 |
2006-01-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
|
|
US7393836B2
(en)
|
2004-07-06 |
2008-07-01 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
JPWO2006006496A1
(ja)
|
2004-07-08 |
2008-04-24 |
アステラス製薬株式会社 |
アズレン誘導体の製造方法及びその合成中間体
|
|
CA2573209A1
(en)
|
2004-07-14 |
2006-01-19 |
Novartis Ag |
Combination of dpp-iv inhibitors and compounds modulating 5-ht3 and/or 5-ht4 receptors
|
|
DE102004034690A1
(de)
|
2004-07-17 |
2006-02-02 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Methyliden-D-xylopyranosyl-und Oxo-D-xylopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
TW200606129A
(en)
|
2004-07-26 |
2006-02-16 |
Chugai Pharmaceutical Co Ltd |
Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
|
|
WO2006010557A1
(de)
|
2004-07-27 |
2006-02-02 |
Boehringer Ingelheim International Gmbh |
D-glucopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
|
JP2006045156A
(ja)
|
2004-08-06 |
2006-02-16 |
Sumitomo Pharmaceut Co Ltd |
縮合ピラゾール誘導体
|
|
WO2006018150A1
(de)
|
2004-08-11 |
2006-02-23 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
|
TW200613275A
(en)
|
2004-08-24 |
2006-05-01 |
Recordati Ireland Ltd |
Lercanidipine salts
|
|
EP1782832A4
(en)
|
2004-08-26 |
2009-08-26 |
Takeda Pharmaceutical |
MEANS FOR THE TREATMENT OF DIABETES
|
|
DE102004043944A1
(de)
|
2004-09-11 |
2006-03-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE102004044221A1
(de)
|
2004-09-14 |
2006-03-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
CN1759834B
(zh)
|
2004-09-17 |
2010-06-23 |
中国医学科学院医药生物技术研究所 |
黄连素或其与辛伐他汀联合在制备用于预防或治疗与血脂有关疾病或症状的产品中用途
|
|
CA2580461A1
(en)
|
2004-09-23 |
2006-04-06 |
Amgen Inc. |
Substituted sulfonamidopropionamides and methods of use
|
|
AR051446A1
(es)
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
DE102004048388A1
(de)
|
2004-10-01 |
2006-04-06 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
RU2007116869A
(ru)
|
2004-10-08 |
2008-11-20 |
Новартис АГ (CH) |
Комбинация органических соединений
|
|
NZ554515A
(en)
|
2004-10-12 |
2009-12-24 |
Glenmark Pharmaceuticals Sa |
Novel dipeptidyl peptidase IV inhibitors, pharmaceutical compositions containing them, and process for their preparation
|
|
KR20070068407A
(ko)
|
2004-10-25 |
2007-06-29 |
노파르티스 아게 |
Ｄｐｐ―ｉｖ 억제제, ｐｐａｒ 항당뇨병제 및메트포르민의 조합물
|
|
DE102005013967A1
(de)
|
2004-11-05 |
2006-10-05 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Bradykinin-B1-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
EP1828216B1
(en)
|
2004-12-16 |
2008-09-10 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
DE102004063099B4
(de)
|
2004-12-22 |
2009-02-12 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung von Thiophenglycosidderivaten
|
|
US20080318922A1
(en)
|
2004-12-24 |
2008-12-25 |
Dainippon Sumitomo Pharma Co., Ltd. |
Bicyclic Pyrrole Derivatives
|
|
KR100760430B1
(ko)
|
2004-12-31 |
2007-10-04 |
한미약품 주식회사 |
당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
|
|
MY148521A
(en)
|
2005-01-10 |
2013-04-30 |
Arena Pharm Inc |
Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
|
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
|
GT200600008A
(es)
|
2005-01-18 |
2006-08-09 |
|
Formulacion de compresion directa y proceso
|
|
TW200637869A
(en)
|
2005-01-28 |
2006-11-01 |
Chugai Pharmaceutical Co Ltd |
The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
|
|
JP5264183B2
(ja)
|
2005-02-23 |
2013-08-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル置換（（ヘテロ）アリールエチニル−ベンジル）−ベンゼン誘導体及びナトリウム依存性グルコース共輸送体２（ｓｇｌｔ２）インヒビターとしてのそれらの使用
|
|
DE602006011453D1
(de)
|
2005-04-15 |
2010-02-11 |
Boehringer Ingelheim Pharma |
Glucopyranosyl-substituierte (heteroaryloxy-benzyl)-benzen-derivate als sglt-inhibitoren
|
|
KR20080000665A
(ko)
|
2005-04-22 |
2008-01-02 |
알란토스 파마슈티컬즈 홀딩, 인코포레이티드 |
디펩티딜 펩티다아제-ⅳ 억제제
|
|
EP1875862B1
(en)
|
2005-04-25 |
2015-07-15 |
Hitachi, Ltd. |
Inspection equipment employing magnetic resonance
|
|
US7723309B2
(en)
|
2005-05-03 |
2010-05-25 |
Boehringer Ingelheim International Gmbh |
Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
|
UA91546C2
(uk)
|
2005-05-03 |
2010-08-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
|
|
US7772191B2
(en)
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
|
KR20080016671A
(ko)
|
2005-05-25 |
2008-02-21 |
와이어쓰 |
치환된 3-시아노퀴놀린 및 그것의 중간체를 합성하는 방법
|
|
GT200600218A
(es)
|
2005-06-10 |
2007-03-28 |
|
Formulación y proceso de compresión directa
|
|
NZ564285A
(en)
|
2005-06-20 |
2010-03-26 |
Decode Genetics Ehf |
Genetic variants in the TCF7L2 gene as diagnostic markers for risk of type 2 diabetes mellitus
|
|
WO2007000445A1
(en)
|
2005-06-29 |
2007-01-04 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
ATE483732T1
(de)
|
2005-07-08 |
2010-10-15 |
Pfizer Ltd |
Madcam-antikörper
|
|
EP1910390B1
(en)
|
2005-07-27 |
2010-05-19 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituted ((hetero)cycloalyklethynyl-benzyl)-benzene derivatives and use thereof as sodium-dependent glucose cotransporter (sglt) inhibitors
|
|
UY29694A1
(es)
|
2005-07-28 |
2007-02-28 |
Boehringer Ingelheim Int |
Metodos para prevenir y tratar trastornos metabolicos y nuevos derivados de pirazol-o-glucosido
|
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
ATE484499T1
(de)
|
2005-08-30 |
2010-10-15 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
|
|
EP1760076A1
(en)
|
2005-09-02 |
2007-03-07 |
Ferring B.V. |
FAP Inhibitors
|
|
BRPI0615882A2
(pt)
|
2005-09-08 |
2011-05-31 |
Boehringer Ingelheim Int |
formas cristalinas de 1-cloro-4-(beta-d-glicopiranos-1-il)-2-(4-etinil-benzil)- benzeno, métodos para sua preparação e o uso para preparar medicamentos do mesmo
|
|
SI1942898T2
(sl)
|
2005-09-14 |
2014-08-29 |
Takeda Pharmaceutical Company Limited |
Dipeptidil-peptidazni inhibitorji za zdravljenje diabetesa
|
|
AR056195A1
(es)
|
2005-09-15 |
2007-09-26 |
Boehringer Ingelheim Int |
Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos
|
|
ATE429430T1
(de)
|
2005-09-16 |
2009-05-15 |
Arena Pharm Inc |
Stoffwechselmodulatoren und behandlung damit verbundener erkrankungen
|
|
KR101368525B1
(ko)
|
2005-09-20 |
2014-03-06 |
노파르티스 아게 |
저혈당 증상을 저하시키기 위한 ｄｐｐ-ⅳ 억제제의 용도
|
|
JOP20180109A1
(ar)
|
2005-09-29 |
2019-01-30 |
Novartis Ag |
تركيبة جديدة
|
|
SG166115A1
(en)
|
2005-09-30 |
2010-11-29 |
Boehringer Ingelheim Vetmed |
Pharmaceutical preparation containing meloxicam
|
|
WO2007050485A2
(en)
|
2005-10-25 |
2007-05-03 |
Merck & Co., Inc. |
Combination of a dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension
|
|
EP1943301A4
(en)
|
2005-11-04 |
2010-01-13 |
Ls Corp |
SYNTHESIS OF MDH POLYMER HYBRID PARTICLES
|
|
US8414921B2
(en)
|
2005-12-16 |
2013-04-09 |
Merck Sharp & Dohme Corp. |
Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
|
|
BRPI0620643A2
(pt)
|
2005-12-23 |
2011-12-20 |
Novartis Ag |
compostos de heterocìclicos condensados úteis como inibidores de dpp-iv, formulações farmacêuticas, produtos e usos dos compostos
|
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
|
BRPI0706423A2
(pt)
|
2006-01-06 |
2011-03-29 |
Novartis Ag |
uso de compostos orgánicos
|
|
ATE517099T1
(de)
|
2006-02-15 |
2011-08-15 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituierte benzonitril-derivate,pharmazeutische zusammensetzungen mit derartigen verbindungen, ihre verwendung und herstellungsverfahren dafür
|
|
WO2007099345A1
(en)
|
2006-03-02 |
2007-09-07 |
Betagenon Ab |
Medical use of bmp-2 and/ or bmp-4
|
|
US8784886B2
(en)
*
|
2006-03-09 |
2014-07-22 |
GlaxoSmithKline, LLC |
Coating capsules with active pharmaceutical ingredients
|
|
US20070264370A1
(en)
*
|
2006-03-31 |
2007-11-15 |
Jeffers Michael G |
Composition and methods for the treatment of joint pain using Angelica gigas Nakai extract and powder as combined with Glucosamine Sulfate, or Chondroitin Sulfate and HCL, or MSM, or aspirin, or Celedrin, and as combinations thereof in powder, pill, capsule, spray, liquid, and gelcap form
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
US8455435B2
(en)
|
2006-04-19 |
2013-06-04 |
Ludwig-Maximilians-Universitat Munchen |
Remedies for ischemia
|
|
PE20080697A1
(es)
|
2006-05-03 |
2008-08-05 |
Boehringer Ingelheim Int |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
|
BRPI0711558A2
(pt)
|
2006-05-04 |
2011-11-08 |
Boeringer Ingelheim Internat Gmbh |
polimorfos
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
CN101442994B
(zh)
|
2006-05-16 |
2013-03-06 |
吉里德科学公司 |
用于治疗恶性血液病的方法和组合物
|
|
KR20070111099A
(ko)
|
2006-05-16 |
2007-11-21 |
영진약품공업주식회사 |
시타글립틴 염산염의 신규 결정형, 이의 제조 방법과 이를포함하는 약학적 조성물
|
|
US20080064717A1
(en)
|
2006-05-19 |
2008-03-13 |
Rajesh Iyengar |
Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme
|
|
KR100858848B1
(ko)
*
|
2006-05-23 |
2008-09-17 |
한올제약주식회사 |
메트포르민 서방정
|
|
US8685452B2
(en)
|
2006-06-16 |
2014-04-01 |
Lek Pharmaceuticals D.D. |
Pharmaceutical composition
|
|
WO2007149797A2
(en)
|
2006-06-19 |
2007-12-27 |
Novartis Ag |
Use of organic compounds
|
|
WO2007148185A2
(en)
|
2006-06-21 |
2007-12-27 |
Pfizer Products Inc. |
Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
|
|
AT503443B1
(de)
|
2006-06-23 |
2007-10-15 |
Leopold Franzens Uni Innsbruck |
Verfahren zur herstellung einer eisfläche für eissportbahnen
|
|
TW200811140A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
|
TW200811147A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
|
WO2008017670A1
(en)
|
2006-08-08 |
2008-02-14 |
Boehringer Ingelheim International Gmbh |
Pyrrolo [3, 2 -d] pyrimidines as dpp-iv inhibitors for the treatment of diabetes mellitus
|
|
US8039441B2
(en)
*
|
2006-08-15 |
2011-10-18 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as SGLT inhibitors and process for their manufacture
|
|
NZ574664A
(en)
|
2006-08-17 |
2012-06-29 |
Wellstat Therapeutics Corp |
Combination treatment for metabolic disorders comprising an incretin mimetic such as exendin or a dppv iv inhibitor
|
|
US20080221174A1
(en)
*
|
2006-08-30 |
2008-09-11 |
Jagotec Ag |
Controlled release nisoldipine compositions
|
|
DE102006042586B4
(de)
|
2006-09-11 |
2014-01-16 |
Betanie B.V. International Trading |
Verfahren zum mikropartikulären Beladen von hochpolymeren Kohlenhydraten mit hydrophoben Wirkflüssigkeiten
|
|
CA2664095A1
(en)
|
2006-09-21 |
2008-03-27 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted difluorobenzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
US8283326B2
(en)
|
2006-10-27 |
2012-10-09 |
Boehringer Ingelheim International Gmbh |
Crystalline form of 4-(beta-D-glucopyranos-1-yl)-1-methyl-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
|
US7956201B2
(en)
|
2006-11-06 |
2011-06-07 |
Hoffman-La Roche Inc. |
Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one
|
|
AR063569A1
(es)
|
2006-11-06 |
2009-02-04 |
Boehringer Ingelheim Int |
Derivados de benzil- benzonitrilo sustituidos con glucopiranosilo medicamentos que contienen a compuestos de este tipo su uso u procedimiento para su fabricacion
|
|
AR063627A1
(es)
|
2006-11-09 |
2009-02-04 |
Boehringer Ingelheim Int |
Terapia combinada con inhibidores de sgl t-2 y sus composiciones farmaceuticas
|
|
WO2008062273A2
(en)
|
2006-11-20 |
2008-05-29 |
Cadila Pharmaceuticals Limited |
Solid oral dosage form having antidiabetic drug combination
|
|
EP2094683B1
(en)
|
2006-12-06 |
2011-10-12 |
GlaxoSmithKline LLC |
Bicyclic compounds and use as antidiabetics
|
|
US7638541B2
(en)
|
2006-12-28 |
2009-12-29 |
Metabolex Inc. |
5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
|
|
CL2008000017A1
(es)
|
2007-01-04 |
2008-08-01 |
Prosidion Ltd |
Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
|
|
CL2008000133A1
(es)
|
2007-01-19 |
2008-05-23 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un compuesto derivado de pirazol-o-glucosido combinado con al menos un segundo agente terapeutico; y uso de la composicion para el tratamiento de diabetes mellitus, cataratas, neuropatia, infarto de miocardio, e
|
|
EP2382972A1
(en)
|
2007-01-26 |
2011-11-02 |
Boehringer Ingelheim International GmbH |
Methods for preventing and treating neurodegenerative disorders
|
|
ATE514692T1
(de)
|
2007-01-26 |
2011-07-15 |
Sanofi Aventis |
Phenothiazin derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
|
ME01239B
(me)
|
2007-02-01 |
2013-06-20 |
Takeda Pharmaceuticals Co |
Čvrsti preparat koji sadrži alogliptin i pioglitazon
|
|
AR065096A1
(es)
|
2007-02-01 |
2009-05-13 |
Takeda Pharmaceutical |
Preparacion solida
|
|
ITFI20070042A1
(it)
|
2007-02-21 |
2008-08-22 |
Laboratori Guidotti Spa |
Formulazione farmaceutica e compressa comprendente detta formulazione.
|
|
WO2008101939A1
(en)
|
2007-02-21 |
2008-08-28 |
Boehringer Ingelheim International Gmbh |
Tetrasubstituted glucopyranosylated benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
WO2008101938A1
(en)
|
2007-02-21 |
2008-08-28 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzonitrile derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
JP2010521492A
(ja)
|
2007-03-15 |
2010-06-24 |
ネクティド，インク． |
徐放性ビグアニド組成物、および即時性ジペプチジルペプチダーゼｉｖ阻害剤組成物を含む抗糖尿病合剤
|
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
|
TW200904454A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
|
|
ES2529149T3
(es)
|
2007-04-03 |
2015-02-17 |
Mitsubishi Tanabe Pharma Corporation |
Una combinación de inhibidor de dipeptidil peptidasa IV y edulcorante para uso en el tratamiento de la obesidad
|
|
AU2008242981B2
(en)
|
2007-04-16 |
2014-06-12 |
Smith & Nephew, Inc. |
Powered surgical system
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
US7910583B2
(en)
|
2007-05-04 |
2011-03-22 |
Bristol-Myers Squibb Company |
[6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists
|
|
US20080287529A1
(en)
|
2007-05-18 |
2008-11-20 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for preparing same
|
|
BRPI0721862B1
(pt)
|
2007-07-09 |
2016-03-15 |
Symrise Ag |
preparação compreendendo sais solúveis estáveis de ácido fenilbenzimidazol sulfônico, e uso de aminoácidos básicos
|
|
CL2008002425A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composición farmacéutica que comprende un inhibidor de sglt2 y 1-(4-metil-quinazolin-2-il)metil-3metil-7-(-2-butin-1-il)-8-(3-(r)-amino-piperidin-1il)-xantina, un inhibidor de dpp iv y su uso para el tratamiento de la obesidad y de la diabetes tipo 1 y 2 y complicaciones de esta.
|
|
PE20090938A1
(es)
|
2007-08-16 |
2009-08-08 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
|
|
PE20090597A1
(es)
|
2007-08-16 |
2009-06-06 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de pirazol-o-glucosido
|
|
FR2920023B1
(fr)
|
2007-08-16 |
2013-02-08 |
Sanofi Aventis |
Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique
|
|
PE20090987A1
(es)
|
2007-08-16 |
2009-08-14 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de pirazol-o-glucosido
|
|
CA2696579C
(en)
|
2007-08-17 |
2017-01-24 |
Boehringer Ingelheim International Gmbh |
Purine derivatives for use in the treatment of fab-related diseases
|
|
HUE035130T2
(en)
|
2007-09-10 |
2018-05-02 |
Janssen Pharmaceutica Nv |
A method for preparing compounds useful as SGLT inhibitors
|
|
CA2705821A1
(en)
|
2007-11-16 |
2009-05-22 |
Novo Nordisk A/S |
Pharmaceutical compositions containing insulin and an insulinotropic peptide
|
|
CN101234105A
(zh)
|
2008-01-09 |
2008-08-06 |
北京润德康医药技术有限公司 |
一种含有二甲双胍和维格列汀的药用组合物及其制备方法
|
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
|
US20090186086A1
(en)
|
2008-01-17 |
2009-07-23 |
Par Pharmaceutical, Inc. |
Solid multilayer oral dosage forms
|
|
TW200936136A
(en)
|
2008-01-28 |
2009-09-01 |
Sanofi Aventis |
Tetrahydroquinoxaline urea derivatives, their preparation and their therapeutic application
|
|
CA2713361A1
(en)
|
2008-02-05 |
2009-08-13 |
Merck Sharp & Dohme Corp. |
Pharmaceutical compositions of a combination of metformin and a dipeptidyl peptidase-iv inhibitor
|
|
US20090226517A1
(en)
*
|
2008-02-06 |
2009-09-10 |
Vinita Umashankar Vyas |
Pharmaceutical formulations comprising duloxetine
|
|
CN101959406A
(zh)
*
|
2008-03-04 |
2011-01-26 |
默沙东公司 |
二甲双胍和二肽基肽酶-ⅳ抑制剂的组合的药物组合物
|
|
CA2717138A1
(en)
|
2008-03-05 |
2009-09-11 |
Takeda Pharmaceutical Company Limited |
5-membered heterocyclic compounds and bicyclic heteroaryl having glucagon antagonistic action useful for treating diabetes
|
|
US8551524B2
(en)
|
2008-03-14 |
2013-10-08 |
Iycus, Llc |
Anti-diabetic combinations
|
|
CA2719507C
(en)
|
2008-03-31 |
2018-03-27 |
Metabolex, Inc. |
Oxymethylene aryl compounds and uses thereof
|
|
PE20091730A1
(es)
*
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
PE20100156A1
(es)
|
2008-06-03 |
2010-02-23 |
Boehringer Ingelheim Int |
Tratamiento de nafld
|
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
NZ604091A
(en)
|
2008-08-15 |
2014-08-29 |
Boehringer Ingelheim Int |
Purin derivatives for use in the treatment of fab-related diseases
|
|
JP2010053576A
(ja)
|
2008-08-27 |
2010-03-11 |
Sumitomo Forestry Co Ltd |
舗装用マット
|
|
BRPI0919288A2
(pt)
|
2008-09-10 |
2015-12-15 |
Boehring Ingelheim Internat Gmbh |
teriapia de combinação para tratamento de diabetes e condições relacionadas.
|
|
UY32177A
(es)
|
2008-10-16 |
2010-05-31 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con control glucémico insuficiente a pesar de la terapia con fármaco, oral o no, antidiabético
|
|
WO2010045656A2
(en)
|
2008-10-17 |
2010-04-22 |
Nectid, Inc. |
Novel sglt2 inhibitor dosage forms
|
|
AU2009331471B2
(en)
|
2008-12-23 |
2015-09-03 |
Boehringer Ingelheim International Gmbh |
Salt forms of organic compound
|
|
AR074990A1
(es)
|
2009-01-07 |
2011-03-02 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
|
|
AR075204A1
(es)
|
2009-01-29 |
2011-03-16 |
Boehringer Ingelheim Int |
Inhibidores de dpp-4 y composiciones farmaceuticas que los comprenden, utiles para tratar enfermedades metabolicas en pacientes pediatricos, particularmente diabetes mellitus tipo 2
|
|
FI2395968T3
(fi)
|
2009-02-13 |
2024-02-27 |
Boehringer Ingelheim Int |
Glukopyranosylidifenylimetaanijohdannaisia sisältävä farmaseuttinen koostumus, niiden farmaseuttinen annostusmuoto, niiden valmistusmenetelmä ja niiden käyttö potilaan glukemiasäädön parantamiseksi
|
|
PE20120017A1
(es)
|
2009-02-13 |
2012-02-12 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un inhibidor de sglt2, un inhibidor de dpp-iv, opcionalmente, un agente antidiabetico adicional, y sus usos
|
|
UY32427A
(es)
|
2009-02-13 |
2010-09-30 |
Boheringer Ingelheim Internat Gmbh |
Composicion farmaceutica, forma farmaceutica, procedimiento para su preparacion, metodos de tratamiento y usos de la misma
|
|
PE20120002A1
(es)
|
2009-02-13 |
2012-02-12 |
Boehringer Ingelheim Int |
Derivados de benceno sustituido con glucopiranosilo como inhibidores de sglt2
|
|
MX2011008416A
(es)
|
2009-02-13 |
2011-09-08 |
Boehringer Ingelheim Int |
Medicaciones antidiabeticas que comprenden un inhibidor de dpp-4 (linagliptina) opcionalmente en combinacion con otros antidiabeticos.
|
|
TW201031661A
(en)
|
2009-02-17 |
2010-09-01 |
Targacept Inc |
Fused benzazepines as neuronal nicotinic acetylcholine receptor ligands
|
|
JP2012520868A
(ja)
|
2009-03-20 |
2012-09-10 |
ファイザー・インク |
３−オキサ−７−アザビシクロ［３．３．１］ノナン
|
|
US8815292B2
(en)
|
2009-04-27 |
2014-08-26 |
Revalesio Corporation |
Compositions and methods for treating insulin resistance and diabetes mellitus
|
|
EP2435033A1
(en)
|
2009-05-27 |
2012-04-04 |
Bristol-Myers Squibb Company |
Methods for treating type 2 diabetes in patients resistant to previous treatment with other anti-diabetic drugs employing an sglt2 inhibitor and compositions thereof
|
|
WO2010140111A1
(en)
*
|
2009-06-02 |
2010-12-09 |
Ranbaxy Laboratories Limited |
Pharmaceutical compositions containing a combination of an antihistamine and a decongestant
|
|
CA2764438A1
(en)
|
2009-06-15 |
2010-12-23 |
Merck Sharp & Dohme Corp. |
Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with pioglitazone
|
|
CN102573807A
(zh)
|
2009-07-21 |
2012-07-11 |
凯克斯生物制药公司 |
柠檬酸铁剂型
|
|
EA020798B1
(ru)
|
2009-09-30 |
2015-01-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
СПОСОБ ПОЛУЧЕНИЯ КРИСТАЛЛИЧЕСКОЙ ФОРМЫ 1-ХЛОР-4-(β-D-ГЛЮКОПИРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГИДРОФУРАН-3-ИЛОКСИ)БЕНЗИЛ]БЕНЗОЛА
|
|
CA2775962C
(en)
|
2009-09-30 |
2017-09-05 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives
|
|
US10610489B2
(en)
|
2009-10-02 |
2020-04-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
|
|
US20120219623A1
(en)
|
2009-10-02 |
2012-08-30 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions comprising bi-1356 and metformin
|
|
JP5775522B2
(ja)
*
|
2009-11-13 |
2015-09-09 |
アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ |
二層錠製剤
|
|
ES2693686T3
(es)
|
2009-11-13 |
2018-12-13 |
Astrazeneca Ab |
Formulaciones de comprimidos de liberación inmediata
|
|
PH12012501037A1
(en)
|
2009-11-27 |
2013-01-14 |
Boehringer Ingelheim Int |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
|
JP2010070576A
(ja)
|
2009-12-28 |
2010-04-02 |
Sato Pharmaceutical Co Ltd |
速溶解性錠剤
|
|
JP2013522279A
(ja)
|
2010-03-18 |
2013-06-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病及び関連状態の治療で用いるｇｐｒ１１９作動薬とｄｄｐ−ｉｖ阻害薬リナグリプチンの組合せ
|
|
EP2368552A1
(en)
|
2010-03-25 |
2011-09-28 |
Boehringer Ingelheim Vetmedica GmbH |
1-[(3-cyano-pyridin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[3-(r)-amino-piperidin-1-yl]-xanthine for the treatment of a metabolic disorder of a predominantly carnivorous non-human animal
|
|
JP2013523681A
(ja)
|
2010-03-30 |
2013-06-17 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｓｇｌｔ２インヒビター及びｐｐａｒ−ガンマアゴニストを含む医薬組成物並びにその使用
|
|
PH12012502161A1
(en)
|
2010-05-05 |
2019-07-17 |
Boehringer Ingelheim Int |
Pharmaceutical formulations comprising pioglitazone and linagliptin
|
|
CA2797310C
(en)
|
2010-05-05 |
2020-03-31 |
Boehringer Ingelheim International Gmbh |
Glp-1 receptor agonist and dpp-4 inhibitor combination therapy
|
|
US8486453B2
(en)
|
2010-06-22 |
2013-07-16 |
Twi Pharmaceuticals, Inc. |
Controlled release compositions with reduced food effect
|
|
KR20230051307A
(ko)
|
2010-06-24 |
2023-04-17 |
베링거 인겔하임 인터내셔날 게엠베하 |
당뇨병 요법
|
|
EP2611442B1
(en)
|
2010-09-03 |
2018-07-04 |
Bristol-Myers Squibb Company |
Drug formulations using water soluble antioxidants
|
|
US20120283169A1
(en)
|
2010-11-08 |
2012-11-08 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
|
WO2012088682A1
(en)
|
2010-12-29 |
2012-07-05 |
Shanghai Fochon Pharmaceutical Co Ltd. |
2-(3-aminopiperidin-1-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-5,7(3h,6h)-dione derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors
|
|
BR112013019026A2
(pt)
|
2011-02-01 |
2016-10-04 |
Astrazeneca Uk Ltd |
formulações farmacêuticas incluindo um composto amina
|
|
US20130035281A1
(en)
|
2011-02-09 |
2013-02-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
UY33937A
(es)
|
2011-03-07 |
2012-09-28 |
Boehringer Ingelheim Int |
Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina
|
|
EA023330B1
(ru)
|
2011-05-10 |
2016-05-31 |
Сандоз Аг |
Полиморфная форма бензоата линаглиптина
|
|
PH12013502487A1
(en)
|
2011-06-03 |
2014-01-20 |
Boehringer Ingelheim Int |
Sglt-2 inhibitors for treating metabolic disorders in patients treated with neuroleptic agents
|
|
US20130035298A1
(en)
|
2011-07-08 |
2013-02-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
ES2713566T3
(es)
|
2011-07-15 |
2019-05-22 |
Boehringer Ingelheim Int |
Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II
|
|
DE102011109492A1
(de)
|
2011-08-04 |
2013-02-07 |
GM Global Technology Operations LLC (n. d. Gesetzen des Staates Delaware) |
Fahrunterstützungsvorrichtung zur Unterstützung der Befahrung enger Fahrwege
|
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
|
MX353496B
(es)
|
2012-01-04 |
2018-01-16 |
Procter & Gamble |
Estructuras fibrosas que contienen activos con múltiples regiones.
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US20130303462A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
JP6374862B2
(ja)
|
2012-05-24 |
2018-08-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
自己免疫性糖尿病、特に、ｌａｄａの治療に使用するためのｄｐｐ−４阻害剤としてのキサンチン誘導体
|
|
WO2013179307A2
(en)
|
2012-05-29 |
2013-12-05 |
Mylan Laboratories Limited |
Stabilized pharmaceutical compositions of saxagliptin
|
|
JP2016510795A
(ja)
|
2013-03-15 |
2016-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
|
|
HK1213818A1
(zh)
|
2013-04-05 |
2016-07-15 |
勃林格殷格翰国际有限公司 |
依帕列净的治疗用途
|
|
ES2702174T3
(es)
|
2013-04-05 |
2019-02-27 |
Boehringer Ingelheim Int |
Usos terapéuticos de empagliflozina
|
|
JP2016520564A
(ja)
|
2013-04-18 |
2016-07-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
医薬組成物、治療方法及びその使用
|
|
JP6507154B2
(ja)
|
2013-06-14 |
2019-04-24 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病及びその合併症を治療するためのｄｄｐ−４阻害薬
|
|
EP3110449B1
(en)
|
2014-02-28 |
2023-06-28 |
Boehringer Ingelheim International GmbH |
Medical use of a dpp-4 inhibitor
|