JP2011503048A5 - - Google Patents
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- JP2011503048A5 JP2011503048A5 JP2010532677A JP2010532677A JP2011503048A5 JP 2011503048 A5 JP2011503048 A5 JP 2011503048A5 JP 2010532677 A JP2010532677 A JP 2010532677A JP 2010532677 A JP2010532677 A JP 2010532677A JP 2011503048 A5 JP2011503048 A5 JP 2011503048A5
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- JP
- Japan
- Prior art keywords
- dosage form
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- amount
- Prior art date
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- 239000002552 dosage form Substances 0.000 claims 45
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical group CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 40
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 30
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 30
- 239000000203 mixture Substances 0.000 claims 27
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 25
- ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 claims 23
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims 20
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims 20
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 18
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 18
- 239000004014 plasticizer Substances 0.000 claims 14
- 238000009472 formulation Methods 0.000 claims 13
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 13
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 13
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 12
- 235000011187 glycerol Nutrition 0.000 claims 10
- 239000001087 glyceryl triacetate Substances 0.000 claims 10
- 235000013773 glyceryl triacetate Nutrition 0.000 claims 10
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 10
- 235000013772 propylene glycol Nutrition 0.000 claims 10
- 229960002622 triacetin Drugs 0.000 claims 10
- 229960003943 hypromellose Drugs 0.000 claims 8
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims 8
- 239000007787 solid Substances 0.000 claims 8
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 7
- 238000004090 dissolution Methods 0.000 claims 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims 7
- 239000001069 triethyl citrate Substances 0.000 claims 7
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 7
- 235000013769 triethyl citrate Nutrition 0.000 claims 7
- 239000000314 lubricant Substances 0.000 claims 6
- 239000007884 disintegrant Substances 0.000 claims 4
- 230000002496 gastric effect Effects 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 3
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 claims 2
- PYGXAGIECVVIOZ-UHFFFAOYSA-N Dibutyl decanedioate Chemical compound CCCCOC(=O)CCCCCCCCC(=O)OCCCC PYGXAGIECVVIOZ-UHFFFAOYSA-N 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 claims 2
- 239000008186 active pharmaceutical agent Substances 0.000 claims 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 claims 2
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 claims 2
- 229940088679 drug related substance Drugs 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 2
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 claims 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 229920003116 HPC-SSL Polymers 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920001213 Polysorbate 20 Polymers 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 229910010413 TiO 2 Inorganic materials 0.000 claims 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 229920001531 copovidone Polymers 0.000 claims 1
- 229960001681 croscarmellose sodium Drugs 0.000 claims 1
- 229960000913 crospovidone Drugs 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 229910021485 fumed silica Inorganic materials 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 229960001375 lactose Drugs 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229960001855 mannitol Drugs 0.000 claims 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- JLFNLZLINWHATN-UHFFFAOYSA-N pentaethylene glycol Chemical compound OCCOCCOCCOCCOCCO JLFNLZLINWHATN-UHFFFAOYSA-N 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 229960002668 sodium chloride Drugs 0.000 claims 1
- 239000008109 sodium starch glycolate Substances 0.000 claims 1
- 229940079832 sodium starch glycolate Drugs 0.000 claims 1
- 229920003109 sodium starch glycolate Polymers 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 229940032147 starch Drugs 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000454 talc Substances 0.000 claims 1
- 229910052623 talc Inorganic materials 0.000 claims 1
- 235000012222 talc Nutrition 0.000 claims 1
- ILJSQTXMGCGYMG-UHFFFAOYSA-N triacetic acid Chemical compound CC(=O)CC(=O)CC(O)=O ILJSQTXMGCGYMG-UHFFFAOYSA-N 0.000 claims 1
- 239000000811 xylitol Substances 0.000 claims 1
- 229960002675 xylitol Drugs 0.000 claims 1
- 235000010447 xylitol Nutrition 0.000 claims 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98638307P | 2007-11-08 | 2007-11-08 | |
| PCT/IB2008/003872 WO2009087483A2 (en) | 2007-11-08 | 2008-11-07 | Pharmaceutical formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011503048A JP2011503048A (ja) | 2011-01-27 |
| JP2011503048A5 true JP2011503048A5 (enExample) | 2012-01-26 |
Family
ID=40721919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532677A Withdrawn JP2011503048A (ja) | 2007-11-08 | 2008-11-01 | 医薬製剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20110117190A1 (enExample) |
| EP (1) | EP2219624A2 (enExample) |
| JP (1) | JP2011503048A (enExample) |
| KR (1) | KR20100096141A (enExample) |
| CN (1) | CN101917978A (enExample) |
| AU (1) | AU2008346205B2 (enExample) |
| BR (1) | BRPI0820381A2 (enExample) |
| CA (1) | CA2705285A1 (enExample) |
| EA (1) | EA201070568A1 (enExample) |
| MX (1) | MX2010005092A (enExample) |
| TW (1) | TW200936186A (enExample) |
| WO (1) | WO2009087483A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7842308B2 (en) * | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) * | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| US7670612B2 (en) * | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
| TWI336260B (en) * | 2002-07-25 | 2011-01-21 | Glaxo Group Ltd | Dosage form suitable for retaining drug substance |
| TW200526274A (en) * | 2003-07-21 | 2005-08-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| PE20060003A1 (es) * | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
| WO2009050193A1 (en) * | 2007-10-15 | 2009-04-23 | Glaxo Group Limited | Method and apparatus for manufacturing filled linkers |
| US8454992B2 (en) * | 2007-10-15 | 2013-06-04 | Capsugel Belgium Nv | Paneled capsule shells for release of pharmaceutical compositions |
| US20090110723A1 (en) * | 2007-10-15 | 2009-04-30 | Mcallister Stephen Mark | Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms |
| JP2011503048A (ja) * | 2007-11-08 | 2011-01-27 | グラクソ グループ リミテッド | 医薬製剤 |
| WO2009150228A2 (en) * | 2008-06-13 | 2009-12-17 | Glaxo Group Limited | Pharmaceutical formulations |
| DE102008031426B4 (de) * | 2008-07-04 | 2014-07-31 | Schott Ag | Verfahren zur Herstellung einer Versiegelungsschicht für Dekorschichten, Glas- oder Glaskeramik-Artikel und dessen Verwendung |
| DE102008031428A1 (de) * | 2008-07-04 | 2010-01-07 | Schott Ag | Dekorative Beschichtung von Glas- oder Glaskeramik-Artikeln |
| GB201010083D0 (en) * | 2010-06-16 | 2010-07-21 | Univ Bradford | Compositions and methods |
| US20120251588A1 (en) * | 2011-03-30 | 2012-10-04 | Miyuki Fukasawa | Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation |
| EP2766423A1 (en) * | 2011-10-12 | 2014-08-20 | Dow Global Technologies LLC | Injection-molded dosage form |
| WO2013090452A1 (en) | 2011-12-12 | 2013-06-20 | Orbis Biosciences, Inc. | Sustained release particle formulations |
| ITTO20120596A1 (it) * | 2012-07-06 | 2014-01-07 | Consiglio Nazionale Ricerche | Procedimento e sistema per assemblare una forma di dosaggio orale, e forma di dosaggio orale |
| PT3003246T (pt) * | 2013-05-31 | 2021-02-22 | Victor Bronshtein | Composições poliméricas contendo produtos biofarmacêuticos estáveis à temperatura ambiente e métodos para a formulação dos mesmos |
| WO2015156922A1 (en) * | 2014-04-08 | 2015-10-15 | Dow Global Technologies Llc | Dispersion comprising an esterified cellulose ether |
| CA2949372C (en) | 2014-06-02 | 2023-08-22 | Teva Pharmaceutical Industries Ltd. | Expandable gastroretentive dosage form |
| TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
| CN107847398B (zh) * | 2016-05-05 | 2019-05-07 | 南京三迭纪医药科技有限公司 | 控制释放的药物剂型 |
| EP3547974B1 (en) | 2016-12-02 | 2023-11-15 | Clexio Biosciences Ltd. | Gastric residence system |
| US20180282527A1 (en) | 2017-03-30 | 2018-10-04 | Shin-Etsu Chemical Co., Ltd. | Injection molding composition containing hypromellose acetate succinate and method for producing same |
| US12214084B2 (en) | 2017-07-11 | 2025-02-04 | Qualicaps Co., Ltd. | Enteric hard capsule |
| WO2019111132A1 (en) | 2017-12-04 | 2019-06-13 | Clexio Biosciences Ltd. | Long acting gastric residence system |
| JP7366893B2 (ja) | 2018-06-22 | 2023-10-23 | クオリカプス株式会社 | 腸溶性硬質カプセル |
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| DE19800927A1 (de) | 1998-01-13 | 1999-07-15 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| DE19812688A1 (de) | 1998-03-23 | 1999-09-30 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| NZ516733A (en) * | 1999-07-30 | 2004-03-26 | Smithkline Beecham Plc | Pharmaceutical formulations for oral dosing that are dosage forms comprising two or more connected sub-units |
| JP4840793B2 (ja) * | 2000-03-23 | 2011-12-21 | 塩野義製薬株式会社 | 撥水性成分を配合することを特徴とする難水溶性薬物の腸溶顆粒製剤 |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| ATE307571T1 (de) * | 2001-02-27 | 2005-11-15 | Pharmazeutische formulierung enthaltend bicalutamid | |
| TWI336260B (en) * | 2002-07-25 | 2011-01-21 | Glaxo Group Ltd | Dosage form suitable for retaining drug substance |
| WO2004024184A1 (ja) * | 2002-09-11 | 2004-03-25 | Takeda Pharmaceutical Company Limited | 徐放性製剤 |
| TW200526274A (en) * | 2003-07-21 | 2005-08-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| JP2007511519A (ja) * | 2003-11-14 | 2007-05-10 | アルザ・コーポレーシヨン | 液状投薬形態物におけるトピラメートの制御放出 |
| WO2005070401A1 (en) * | 2004-01-16 | 2005-08-04 | Glaxo Group Limited | Encapsulation of lipid-based formulations in enteric polymers |
| PE20060003A1 (es) | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
| JP2008535837A (ja) * | 2005-04-06 | 2008-09-04 | マリンクロッド・インコーポレイテッド | マトリックスをベースとするパルス放出製剤 |
| US8454992B2 (en) * | 2007-10-15 | 2013-06-04 | Capsugel Belgium Nv | Paneled capsule shells for release of pharmaceutical compositions |
| US20090110723A1 (en) * | 2007-10-15 | 2009-04-30 | Mcallister Stephen Mark | Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms |
| JP2011503048A (ja) * | 2007-11-08 | 2011-01-27 | グラクソ グループ リミテッド | 医薬製剤 |
-
2008
- 2008-11-01 JP JP2010532677A patent/JP2011503048A/ja not_active Withdrawn
- 2008-11-01 EP EP08870466A patent/EP2219624A2/en not_active Ceased
- 2008-11-07 US US12/741,596 patent/US20110117190A1/en not_active Abandoned
- 2008-11-07 AU AU2008346205A patent/AU2008346205B2/en not_active Ceased
- 2008-11-07 CN CN2008801243003A patent/CN101917978A/zh active Pending
- 2008-11-07 KR KR1020107012468A patent/KR20100096141A/ko not_active Withdrawn
- 2008-11-07 US US12/266,896 patent/US20090148518A1/en not_active Abandoned
- 2008-11-07 EA EA201070568A patent/EA201070568A1/ru unknown
- 2008-11-07 CA CA2705285A patent/CA2705285A1/en not_active Abandoned
- 2008-11-07 MX MX2010005092A patent/MX2010005092A/es not_active Application Discontinuation
- 2008-11-07 BR BRPI0820381-4A patent/BRPI0820381A2/pt not_active IP Right Cessation
- 2008-11-07 WO PCT/IB2008/003872 patent/WO2009087483A2/en not_active Ceased
- 2008-11-10 TW TW097143400A patent/TW200936186A/zh unknown
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