JP2012097088A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012097088A5 JP2012097088A5 JP2011262441A JP2011262441A JP2012097088A5 JP 2012097088 A5 JP2012097088 A5 JP 2012097088A5 JP 2011262441 A JP2011262441 A JP 2011262441A JP 2011262441 A JP2011262441 A JP 2011262441A JP 2012097088 A5 JP2012097088 A5 JP 2012097088A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- present
- amount
- molecular weight
- blend
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002552 dosage form Substances 0.000 claims 32
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 15
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 15
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 15
- 239000000203 mixture Substances 0.000 claims 14
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical group CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 12
- 229920001577 copolymer Polymers 0.000 claims 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims 7
- 239000000314 lubricant Substances 0.000 claims 6
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 4
- 239000007884 disintegrant Substances 0.000 claims 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 239000004094 surface-active agent Substances 0.000 claims 3
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 claims 2
- PYGXAGIECVVIOZ-UHFFFAOYSA-N Dibutyl decanedioate Chemical compound CCCCOC(=O)CCCCCCCCC(=O)OCCCC PYGXAGIECVVIOZ-UHFFFAOYSA-N 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 claims 2
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical group CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 claims 2
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 2
- -1 hydroxypropyl Chemical group 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 239000004014 plasticizer Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000000346 sugar Nutrition 0.000 claims 2
- 239000000454 talc Substances 0.000 claims 2
- 229910052623 talc Inorganic materials 0.000 claims 2
- 235000012222 talc Nutrition 0.000 claims 2
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 claims 2
- 239000001069 triethyl citrate Substances 0.000 claims 2
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 2
- 235000013769 triethyl citrate Nutrition 0.000 claims 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 102000004856 Lectins Human genes 0.000 claims 1
- 108090001090 Lectins Proteins 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920001213 Polysorbate 20 Polymers 0.000 claims 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 claims 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920001531 copovidone Polymers 0.000 claims 1
- 229960001681 croscarmellose sodium Drugs 0.000 claims 1
- 229960000913 crospovidone Drugs 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 229910021485 fumed silica Inorganic materials 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 229960001375 lactose Drugs 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 239000002523 lectin Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229960001855 mannitol Drugs 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 1
- 235000013772 propylene glycol Nutrition 0.000 claims 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 229960002668 sodium chloride Drugs 0.000 claims 1
- 239000008109 sodium starch glycolate Substances 0.000 claims 1
- 229940079832 sodium starch glycolate Drugs 0.000 claims 1
- 229920003109 sodium starch glycolate Polymers 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 229940032147 starch Drugs 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- ILJSQTXMGCGYMG-UHFFFAOYSA-N triacetic acid Chemical compound CC(=O)CC(=O)CC(O)=O ILJSQTXMGCGYMG-UHFFFAOYSA-N 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000000811 xylitol Substances 0.000 claims 1
- 229960002675 xylitol Drugs 0.000 claims 1
- 235000010447 xylitol Nutrition 0.000 claims 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55249904P | 2004-03-12 | 2004-03-12 | |
| US60/552,499 | 2004-03-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503046A Division JP2007528901A (ja) | 2004-03-12 | 2005-03-11 | 医薬製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012097088A JP2012097088A (ja) | 2012-05-24 |
| JP2012097088A5 true JP2012097088A5 (enExample) | 2013-03-07 |
Family
ID=34993424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503046A Ceased JP2007528901A (ja) | 2004-03-12 | 2005-03-11 | 医薬製剤 |
| JP2011262441A Withdrawn JP2012097088A (ja) | 2004-03-12 | 2011-11-30 | 医薬製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503046A Ceased JP2007528901A (ja) | 2004-03-12 | 2005-03-11 | 医薬製剤 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20070178156A1 (enExample) |
| EP (1) | EP1729744A4 (enExample) |
| JP (2) | JP2007528901A (enExample) |
| KR (3) | KR101242988B1 (enExample) |
| CN (1) | CN1953739B (enExample) |
| AR (1) | AR048033A1 (enExample) |
| AU (1) | AU2005222612C1 (enExample) |
| BR (1) | BRPI0508342A (enExample) |
| CA (1) | CA2559227A1 (enExample) |
| IL (1) | IL177566A (enExample) |
| MA (1) | MA28489B1 (enExample) |
| NO (1) | NO20064570L (enExample) |
| NZ (1) | NZ549264A (enExample) |
| PE (1) | PE20060003A1 (enExample) |
| RU (2) | RU2447885C2 (enExample) |
| TW (2) | TW200539903A (enExample) |
| WO (1) | WO2005089726A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL147826A0 (en) * | 1999-07-30 | 2002-08-14 | Smithkline Beecham Plc | Multi-component pharmaceutical dosage form |
| US7842308B2 (en) * | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| MY142179A (en) * | 2002-07-25 | 2010-10-15 | Glaxo Group Ltd | Multicomponent pharmaceutical dosage form |
| EP1608347B1 (en) * | 2003-03-28 | 2014-08-13 | Sigmoid Pharma Limited | Solid oral dosage form containing seamless microcapsules |
| TW200526274A (en) | 2003-07-21 | 2005-08-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| US20070292523A1 (en) * | 2004-09-27 | 2007-12-20 | Joey Moodley | Dihydropyrimidine Formulations |
| EP1836665B1 (en) * | 2004-11-19 | 2013-01-16 | GlaxoSmithKline LLC | Method for customized dispensing of variable dose drug combination products for individualizing of therapies |
| WO2007078290A1 (en) * | 2005-12-30 | 2007-07-12 | Accu-Break Technologies, Inc. | Adhesively bonded dosage form |
| AR060103A1 (es) * | 2006-02-09 | 2008-05-28 | Alba Therapeutics Corp | Formulaciones para un efector de uniones apretadas |
| CN101460191A (zh) * | 2006-06-02 | 2009-06-17 | 特瓦制药工业有限公司 | 包含湿敏性药物的稳定制剂及其制备方法 |
| US8034776B2 (en) | 2006-10-26 | 2011-10-11 | Alba Therapeutics Corporation | Materials and methods for the treatment of celiac disease |
| EP2061440A2 (en) | 2007-04-04 | 2009-05-27 | Sigmoid Pharma Limited | A pharmaceutical composition of tacrolimus |
| ES2963291T3 (es) * | 2007-04-26 | 2024-03-26 | Sublimity Therapeutics Ltd | Fabricación de múltiples minicápsulas |
| RU2463079C2 (ru) * | 2007-04-27 | 2012-10-10 | Эндо Фармасьютикалз Солюшнз Инк. | Разделительные агенты для имплантируемого устройства и способы их применения |
| JP2010526053A (ja) * | 2007-05-01 | 2010-07-29 | シグモイド・ファーマ・リミテッド | ニモジピン医薬組成物 |
| CN101827573A (zh) * | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 已装填的连接件的制造装置和方法 |
| CN101827571A (zh) | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 用于释放一种或多种药物成分的多部分剂型的连接件及所得剂型 |
| EP2209455A1 (en) * | 2007-10-15 | 2010-07-28 | Glaxo Group Limited | Paneled capsule shells for release of pharmaceutical compositions |
| EP2219624A2 (en) | 2007-11-08 | 2010-08-25 | Glaxo Group Limited | Pharmaceutical formulations |
| EP2227226B1 (en) * | 2007-12-21 | 2016-10-26 | Johnson & Johnson Consumer Inc. | Manufacture of a tablet |
| JP2012502883A (ja) * | 2008-06-13 | 2012-02-02 | グラクソ グループ リミテッド | 医薬製剤 |
| IT1393245B1 (it) * | 2008-07-24 | 2012-04-12 | Universita' Degli Studi Di Milano | Forme farmaceutiche per il rilascio tempo-specifico di farmaci |
| US8900634B2 (en) * | 2008-11-03 | 2014-12-02 | Nal Pharmaceuticals, Ltd. | Diethylstilbestrol dosage form and methods of treatment using thereof |
| EP2564839B1 (en) | 2009-01-09 | 2016-05-11 | Forward Pharma A/S | Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix |
| EP2471518B1 (en) | 2009-05-18 | 2017-08-23 | Sigmoid Pharma Limited | Composition comprising oil drops |
| EP2464341B1 (en) | 2009-08-12 | 2022-07-06 | Sublimity Therapeutics Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
| EP2544667B1 (en) * | 2010-03-09 | 2018-11-14 | Alkermes Pharma Ireland Limited | Alcohol resistant enteric pharmaceutical compositions |
| US9198868B2 (en) * | 2010-10-26 | 2015-12-01 | Capsugel Belgium Nv | Bulk enteric capsule shells |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| US9649278B2 (en) | 2011-10-12 | 2017-05-16 | Dow Global Technologies Llc | Injection-molded dosage form |
| GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
| EP3065720A1 (en) | 2013-11-04 | 2016-09-14 | Capsugel Belgium NV | Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole |
| GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
| TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
| WO2016071515A1 (en) | 2014-11-07 | 2016-05-12 | Sigmoid Pharma Limited | Compositions comprising cyclosporin |
| US20160331689A1 (en) | 2015-05-12 | 2016-11-17 | SE Tylose USA, Inc. | Aqueous enteric coating composition |
| AU2016342374B2 (en) * | 2015-10-23 | 2022-08-04 | Nortiva Bio, Inc. | Gastric residence systems for sustained release of therapeutic agents and methods of use thereof |
| KR102796240B1 (ko) | 2015-12-08 | 2025-04-16 | 린드라 테라퓨틱스 인코퍼레이티드 | 위 체류 시스템을 위한 기하 구성형태 |
| US12109305B2 (en) | 2016-05-27 | 2024-10-08 | Lyndra Therapeutics, Inc. | Materials architecture for gastric residence systems |
| EP3518902A4 (en) | 2016-09-30 | 2020-07-08 | Lyndra, Inc. | GASTRIC RESIDENCE SYSTEMS FOR LONG-TERM ADMINISTRATION OF ADAMANTANE CLASS MEDICINES |
| TWI811221B (zh) | 2017-06-09 | 2023-08-11 | 美商萊恩卓治療公司 | 具有釋放速率調節膜之胃的滯留系統 |
| WO2019082171A1 (en) * | 2017-10-27 | 2019-05-02 | Alvit Pharma | ORAL CANNABINOID COMPOSITIONS HAVING ENHANCED BIOAVAILABILITY |
| CN112499717B (zh) * | 2020-12-10 | 2021-10-22 | 江南大学 | 一种聚合物包含膜在染料吸附中的应用 |
Family Cites Families (166)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3186910A (en) | 1962-03-08 | 1965-06-01 | Jacob A Glassman | Method for producing peroral capsules |
| US3228789A (en) * | 1962-10-22 | 1966-01-11 | Jacob A Glassman | Peroral capsules and tablets and the method for making same |
| US3278520A (en) | 1963-02-08 | 1966-10-11 | Hercules Inc | Hydroxypropyl cellulose and process |
| US3394983A (en) | 1963-06-14 | 1968-07-30 | American Cyanamid Co | Dip-dyeing capsules |
| FR1454013A (fr) | 1965-08-18 | 1966-07-22 | Pluripharm | Mode de présentation de deux médicaments associés |
| US3399803A (en) | 1966-10-11 | 1968-09-03 | Parke Davis & Co | Self-locking medicament capsule |
| US3779942A (en) | 1970-12-04 | 1973-12-18 | Minnesota Mining & Mfg | Capsules and process for forming capsules |
| US3723312A (en) * | 1970-12-18 | 1973-03-27 | Ppg Industries Inc | Combined stain retardant and separator interleaving material for glass sheets |
| DE2428397C3 (de) | 1974-06-12 | 1978-05-18 | Scherer Hartkapsel Gmbh, 6930 Eberbach | Zweiteilige Kapsel aus Hartgelatine |
| NL7610038A (en) | 1976-09-09 | 1978-03-13 | Tapanahony N V | Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively |
| DE2722822C2 (de) * | 1977-05-20 | 1984-11-08 | Capsugel AG, Basel | Verfahren zum Herstellen einer zum Aufnehmen eines viskosen Stoffes, insbesondere eines flüssigen Arzneimittels, geeigneten Steckkapsel |
| US4250097A (en) | 1978-03-08 | 1981-02-10 | Syntex (U.S.A.) Inc. | Compositions for and a method of preventing diabetic complications |
| FI63335B (fi) | 1979-02-02 | 1983-02-28 | Orion Yhtymae Oy | Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne |
| US4281763A (en) | 1979-10-31 | 1981-08-04 | Pace Joseph A | Two-piece hardshell, soluble and digestible liquid containing gelatin capsule |
| US4498080A (en) * | 1980-12-31 | 1985-02-05 | Braintech, Inc. | Apparatus and method for topographic display of multichannel data |
| US4417591A (en) | 1980-12-31 | 1983-11-29 | Braintech, Inc. | Apparatus and method for topographic display of multichannel EEG data |
| US4766728A (en) * | 1983-03-28 | 1988-08-30 | Rexa Corporation | Flow matching valve and hydraulic system employing same |
| USRE34390E (en) | 1980-12-31 | 1993-09-28 | Nicolet Instrument Corporation | Apparatus and method for topographic display of multichannel EEG data |
| US4378817A (en) * | 1981-07-06 | 1983-04-05 | Superior Valve Corporation | Slide valve assembly |
| EP0091908A1 (en) | 1981-10-21 | 1983-10-26 | SMITH, Charles E | A method and composition for substrate coating |
| EG16028A (en) * | 1982-03-26 | 1986-12-30 | Warner Lambert Co | Apparatus and method for molding capsules |
| US4655840A (en) | 1982-03-26 | 1987-04-07 | Warner-Lambert Company | Hydrophilic polymer compositions for injection molding |
| US4790881A (en) | 1982-03-26 | 1988-12-13 | Warner-Lambert Company | Molded hydrophilic polymer |
| FR2524311A1 (fr) | 1982-04-05 | 1983-10-07 | Azalbert Gilles | Gelule compartimentee aux fins d'ingestions simultanees a effets differes |
| US4550238A (en) | 1982-11-05 | 1985-10-29 | Warner-Lambert Company | Apparatus and method for sealing capsules |
| USD285837S (en) | 1982-12-20 | 1986-09-23 | Warner-Lambert Company | Pharmaceutical capsule |
| US4487327A (en) | 1982-12-21 | 1984-12-11 | Grayson Robert E | Locking capsule |
| US4557180A (en) | 1983-03-28 | 1985-12-10 | Rexa Corporation | Control valve and hydraulic system employing same |
| US4696163A (en) | 1983-03-28 | 1987-09-29 | Rexa Corporation | Control valve and hydraulic system employing same |
| US4625513A (en) | 1983-03-28 | 1986-12-02 | Rexa Corporation | Controlled flow hydraulic system |
| US4543138A (en) | 1983-07-07 | 1985-09-24 | Eli Lilly & Company | Capsule-sealing method and apparatus |
| US4564363A (en) * | 1983-07-13 | 1986-01-14 | Smithkline Beckman Corporation | Delayed action assembly |
| US4576284A (en) * | 1983-12-02 | 1986-03-18 | Warner-Lambert Company | Closing of filled capsules |
| CH661878A5 (de) | 1983-11-04 | 1987-08-31 | Warner Lambert Co | Kapsel-dosierungsformen. |
| US4738724A (en) * | 1983-11-04 | 1988-04-19 | Warner-Lambert Company | Method for forming pharmaceutical capsules from starch compositions |
| US4738817A (en) * | 1983-11-17 | 1988-04-19 | Warner-Lambert Company | Method for forming pharmaceutical capsules from hydrophilic polymers |
| US4673438A (en) | 1984-02-13 | 1987-06-16 | Warner-Lambert Company | Polymer composition for injection molding |
| EP0164669B1 (de) | 1984-06-13 | 1991-01-23 | Röhm Gmbh | Verfahren zum Überziehen von Arzneiformen |
| US4629621A (en) * | 1984-07-23 | 1986-12-16 | Zetachron, Inc. | Erodible matrix for sustained release bioactive composition |
| US5082655A (en) | 1984-07-23 | 1992-01-21 | Zetachron, Inc. | Pharmaceutical composition for drugs subject to supercooling |
| US4678516A (en) | 1984-10-09 | 1987-07-07 | The Dow Chemical Company | Sustained release dosage form based on highly plasticized cellulose ether gels |
| DE3438291A1 (de) | 1984-10-19 | 1986-04-24 | Röhm GmbH, 6100 Darmstadt | Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimitteln |
| GB2172569A (en) | 1985-03-21 | 1986-09-24 | Warner Lambert Co | Improved capsule construction |
| EP0211079A4 (en) | 1985-01-31 | 1988-02-15 | Fujisawa Pharmaceutical Co | Soft multi-chamber capsule and method of and apparatus for manufacturing same. |
| DE3524963A1 (de) | 1985-07-12 | 1987-01-22 | Scherer R P Hartkapsel Gmbh | Zweiteilige steckkapsel |
| IL77186A0 (en) * | 1985-11-29 | 1986-04-29 | Touitou Elka | Pharmaceutical insulin composition |
| DE3543912A1 (de) | 1985-12-12 | 1987-06-19 | Linde Ag | Steuergeraet |
| EP0228067B1 (en) | 1985-12-26 | 1991-09-18 | Taisho Pharmaceutical Co. Ltd | Seamless soft capsule |
| US4764378A (en) | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
| US4928840A (en) | 1986-02-25 | 1990-05-29 | American Home Products Corporation | Tamper proof encapsulated medicaments |
| CH674800A5 (enExample) | 1986-03-12 | 1990-07-31 | Warner Lambert Co | |
| DE3612212A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
| US4936461A (en) | 1986-09-18 | 1990-06-26 | Makiej Jr Walter J | Multidose capsules |
| US4793493A (en) | 1986-09-18 | 1988-12-27 | Makiej Jr Walter J | Multidose capsules |
| DE3631826A1 (de) | 1986-09-19 | 1988-03-31 | Roehm Gmbh | Herstellung eines methylmethacrylat-copolymerisats |
| US5074426A (en) | 1986-11-13 | 1991-12-24 | Warner-Lambert Company | Dividable capsule |
| KR890003520Y1 (ko) | 1986-12-20 | 1989-05-27 | 주식회사 서흥캅셀 | 의약용 캅셀 |
| US4724019A (en) * | 1987-03-20 | 1988-02-09 | Warner-Lambert Company | Method and apparatus for sealing capsules |
| US5236689A (en) * | 1987-06-25 | 1993-08-17 | Alza Corporation | Multi-unit delivery system |
| US4795644A (en) * | 1987-08-03 | 1989-01-03 | Merck & Co., Inc. | Device for pH independent release of drugs through the Donnan-like influence of charged insoluble resins |
| DE3727894A1 (de) | 1987-08-21 | 1989-03-02 | Stephan Dieter | Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge |
| DE3735260A1 (de) | 1987-10-17 | 1989-04-27 | Bosch Gmbh Robert | Verschliessvorrichtung fuer zweiteilige kapseln |
| DE3830013C2 (de) | 1988-09-03 | 1996-10-17 | Bosch Gmbh Robert | Füll- und Schließmaschine für zweiteilige Kapseln |
| US4944906A (en) | 1988-10-11 | 1990-07-31 | Spirex Corporation | Methods of injection molding and extruding wet hygroscopic ionomers |
| US5135752A (en) | 1988-10-14 | 1992-08-04 | Zetachron, Inc. | Buccal dosage form |
| US5139790A (en) * | 1988-10-14 | 1992-08-18 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
| US5244668A (en) | 1988-10-14 | 1993-09-14 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
| US5004601A (en) * | 1988-10-14 | 1991-04-02 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
| US4936074A (en) | 1988-11-17 | 1990-06-26 | D. M. Graham Laboratories, Inc. | Process for preparing solid encapsulated medicament |
| DE3902653A1 (de) | 1989-01-30 | 1990-08-02 | Roehm Gmbh | Elastomere acrylharze |
| US6200600B1 (en) | 1989-02-16 | 2001-03-13 | Btg International Limited | Controlled delay release device |
| DE3907019A1 (de) * | 1989-03-04 | 1990-09-06 | Roehm Gmbh | Thermoplastisch verarbeitbare loesungsmittelbestaendige kunststoffmischungen |
| JPH0729926B2 (ja) | 1989-07-25 | 1995-04-05 | 大塚製薬株式会社 | 易吸収性製剤用組成物 |
| US5456919A (en) | 1989-12-29 | 1995-10-10 | Bristol-Myers Squibb Company | Capsule and caplet combination |
| DE4002904A1 (de) * | 1990-02-01 | 1991-08-08 | Roehm Gmbh | Verfahren zum imidieren eines methacrylester-polymerisats |
| AU653793B2 (en) | 1991-01-30 | 1994-10-13 | Alza Corporation | Osmotic device for delayed delivery of agent |
| US5976571A (en) * | 1991-01-31 | 1999-11-02 | Port Systems, L.L.C. | Method for making a multi-stage drug delivery system |
| US5387421A (en) * | 1991-01-31 | 1995-02-07 | Tsrl, Inc. | Multi stage drug delivery system |
| US5674530A (en) | 1991-01-31 | 1997-10-07 | Port Systems, L.L.C. | Method for making a multi-stage drug delivery system |
| CA2068402C (en) | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
| DE4121652A1 (de) | 1991-06-29 | 1993-01-07 | Roehm Gmbh | Schlagzaeh-modifizierungsmittel |
| US5225202A (en) * | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
| DE4138513A1 (de) | 1991-11-23 | 1993-05-27 | Basf Ag | Feste pharmazeutische retardform |
| GB9223172D0 (en) * | 1992-11-05 | 1992-12-16 | Scherer Corp R P | Capsule construction |
| GB9223144D0 (en) * | 1992-11-05 | 1992-12-16 | Scherer Corp R P | Controlled release device |
| US5312008A (en) * | 1993-05-26 | 1994-05-17 | Davis Bradford L | Personal time capsule |
| WO1996010996A1 (en) | 1993-07-21 | 1996-04-18 | The University Of Kentucky Research Foundation | A multicompartment hard capsule with control release properties |
| US5443461A (en) * | 1993-08-31 | 1995-08-22 | Alza Corporation | Segmented device for simultaneous delivery of multiple beneficial agents |
| GB9325445D0 (en) | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
| DE4402666A1 (de) | 1994-01-29 | 1995-08-03 | Roehm Gmbh | Verfahren zum kurzzeitigen Behandeln einer Kunststoffschmelze mit einem flüssigen Behandlungsmittel und dabei hergestellter thermoplastischer Kunststoff |
| DE4413350A1 (de) | 1994-04-18 | 1995-10-19 | Basf Ag | Retard-Matrixpellets und Verfahren zu ihrer Herstellung |
| ATE226090T1 (de) * | 1994-04-22 | 2002-11-15 | Yamanouchi Pharma Co Ltd | Kolon-spezifisches arzneistofffreisetzungssystem |
| DE19509807A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen |
| DE9414065U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
| DE9414066U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| DE4445498A1 (de) | 1994-12-20 | 1996-06-27 | Roehm Gmbh | Universell verträgliche Pigmentdispergatoren |
| DE19504832A1 (de) | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| DE19504831A1 (de) | 1995-02-14 | 1996-09-05 | Basf Ag | Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose |
| DE29502547U1 (de) | 1995-02-16 | 1995-03-30 | Röhm GmbH, 64293 Darmstadt | Thermoplastisches Überzugs- und Bindemittel für Arzneiformen |
| DE19509805A1 (de) | 1995-03-21 | 1996-09-26 | Basf Ag | Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica |
| SG80553A1 (en) | 1995-07-20 | 2001-05-22 | Tanabe Seiyaku Co | Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract |
| DE19531277A1 (de) * | 1995-08-25 | 1997-02-27 | Basf Ag | Verwendung von Lipiden als Hilfsmittel bei der Herstellung von festen Arzneiformen nach dem Schmelzextrusionsverfahren |
| US5769267A (en) | 1995-11-09 | 1998-06-23 | Warner-Lambert Company | Container |
| DE19544562B4 (de) | 1995-11-30 | 2004-05-27 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von Poly(meth)acrylimiden mit bei thermischer Belastung verbesserter Farbstabilität und daraus erhältliche Formkörper |
| DE19701441C2 (de) * | 1997-01-17 | 1998-11-05 | Roehm Gmbh | Verfahren zur Herstellung farbneutraler Polymethylmethacrylat-Formmassen |
| DE19718597C1 (de) | 1997-05-02 | 1999-01-07 | Roehm Gmbh | Zweistufiges Verfahren zur Entwässerung von Kunststoffdispersionen |
| DE19721467A1 (de) * | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
| IL133080A0 (en) * | 1997-07-01 | 2001-03-19 | Pfizer | Sertraline salts and sustained-release dosage forms of sertraline |
| DE19733505A1 (de) | 1997-08-01 | 1999-02-04 | Knoll Ag | Schnell wirksames Analgeticum |
| DE19753298A1 (de) * | 1997-12-01 | 1999-06-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| DE19753300A1 (de) | 1997-12-01 | 1999-06-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| DE19753299A1 (de) | 1997-12-01 | 1999-06-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| DE19800927A1 (de) | 1998-01-13 | 1999-07-15 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| DE19835346A1 (de) | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
| DE19843904A1 (de) * | 1998-09-24 | 2000-03-30 | Basf Ag | Feste Dosierungsform mit polymerem Bindemittel |
| US6139875A (en) | 1998-09-29 | 2000-10-31 | Eastman Chemical Company | Aqueous enteric coating composition and low gastric permeability enteric coating |
| CA2352389C (en) * | 1998-11-27 | 2009-01-20 | Kanji Takada | An oral formulation for gastrointestinal drug delivery |
| US6797283B1 (en) * | 1998-12-23 | 2004-09-28 | Alza Corporation | Gastric retention dosage form having multiple layers |
| IT1316684B1 (it) * | 1999-03-13 | 2003-04-24 | Bosch Gmbh Robert | Supporto delle parti di capsule in una macchina di caricamento e dichiusura per capsule in due parti |
| US6248807B1 (en) * | 1999-03-15 | 2001-06-19 | Fina Technology, Inc. | Method for the preparation of core-shell morphologies from polybutadiene-polystyrene graft copolymers |
| DE19914605A1 (de) | 1999-03-30 | 2000-10-05 | Roehm Gmbh | Polyalkylmethacrylat-Plastisole mit verbesserten Fließeigenschaften |
| IL147826A0 (en) * | 1999-07-30 | 2002-08-14 | Smithkline Beecham Plc | Multi-component pharmaceutical dosage form |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| DE19960494A1 (de) * | 1999-12-15 | 2001-06-21 | Knoll Ag | Vorrichtung und Verfahren zum Herstellen von festen wirkstoffhaltigen Formen |
| DE19961334A1 (de) * | 1999-12-17 | 2001-06-21 | Roehm Gmbh | Spritzgußverfahren für neutrale und säuregruppenhaltige (Meth)acrylat-Copolymere |
| GB0001621D0 (en) | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| MXPA02008023A (es) * | 2000-02-18 | 2005-06-30 | Yeda Res & Dev | Formulaciones de copolimero 1 para dosificacion oral, nasal y pulmonar. |
| US6551617B1 (en) | 2000-04-20 | 2003-04-22 | Bristol-Myers Squibb Company | Taste masking coating composition |
| US6270797B1 (en) * | 2000-05-18 | 2001-08-07 | Usv Limited | Sustained release pharmaceutical composition containing glipizide and method for producing same |
| DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| DE10043868A1 (de) * | 2000-09-04 | 2002-04-04 | Roehm Gmbh | PMMA Formmassen mit verbesserter Schlagzähigkeit |
| DE10054051A1 (de) * | 2000-10-31 | 2002-05-29 | Roehm Gmbh | PMMA-Formmasse mit verbesserter Kälteschlagzähigkeit |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| US7842308B2 (en) * | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US20050175687A1 (en) | 2001-01-30 | 2005-08-11 | Mcallister Stephen M. | Pharmaceutical formulations |
| DE10127134A1 (de) | 2001-06-05 | 2002-12-12 | Roehm Gmbh | verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß |
| JP4426286B2 (ja) * | 2001-07-10 | 2010-03-03 | テバ ファーマシューティカル インダストリーズ リミティド | 0次、0次−二相性、上昇型又は下降型薬物放出のための薬物送達システム |
| US6949154B2 (en) | 2001-07-28 | 2005-09-27 | Boehringer Ingelheim Pharma Kg | Method and apparatus for sealing medicinal capsules |
| US7217381B2 (en) * | 2001-09-28 | 2007-05-15 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
| USD481456S1 (en) | 2002-01-30 | 2003-10-28 | Smithkline Beecham P.L.C. | Capsule |
| DE10204890A1 (de) | 2002-02-06 | 2003-08-14 | Roehm Gmbh | Schlagzähe Formmasse und Formkörper |
| US7670612B2 (en) * | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
| US20030194430A1 (en) | 2002-04-10 | 2003-10-16 | Miller Frederick H. | Process for encapsulating multi-phase, multi-compartment capsules for therapeutic compositions |
| MY142179A (en) * | 2002-07-25 | 2010-10-15 | Glaxo Group Ltd | Multicomponent pharmaceutical dosage form |
| USD506545S1 (en) | 2002-07-29 | 2005-06-21 | Smithkline Beecham P.L.C. | Capsule linker |
| DE10243062A1 (de) | 2002-09-16 | 2004-03-25 | Röhm GmbH & Co. KG | Heißwasserwechseltestbeständiges Sanitärmaterial aus PMMA-Formmasse oder schlagzäher PMMA-Formmasse |
| DE10260089A1 (de) | 2002-12-19 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von wässrigen Dispersionen |
| DE10260065A1 (de) | 2002-12-19 | 2004-07-01 | Röhm GmbH & Co. KG | Kern-Schale-Teilchen zur Schlagzähmodifizierung von Poly(meth)acrylat-Formmassen |
| DE10329938A1 (de) | 2003-07-02 | 2005-03-17 | Röhm GmbH & Co. KG | Kunststoffkörper mit mikrostrukturierter Oberfläche |
| TW200526274A (en) | 2003-07-21 | 2005-08-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| DE10349142A1 (de) * | 2003-10-17 | 2005-05-12 | Roehm Gmbh | Polymermischung sowie deren Verwendung für Spritzgußteile |
| DE10349144A1 (de) * | 2003-10-17 | 2005-05-12 | Roehm Gmbh | Polymermischung für mattierte Spritzgußteile |
| DE10351535A1 (de) | 2003-11-03 | 2005-06-09 | Röhm GmbH & Co. KG | Mehrschichtfolie aus (Meth)acrylatcopolymer und Polycarbonat |
| DE10354379A1 (de) | 2003-11-20 | 2005-06-23 | Röhm GmbH & Co. KG | Formmasse, enthaltend ein Mattierungsmittel |
| US20070160677A1 (en) | 2004-01-16 | 2007-07-12 | Pillai Raviraj S | Encapsulation of lipid-based formulations in enteric polymers |
| DE102004022540A1 (de) | 2004-05-05 | 2005-12-08 | Röhm GmbH & Co. KG | Formmasse für Formkörper mit hoher Witterungsbeständigkeit |
| JP4354360B2 (ja) * | 2004-07-26 | 2009-10-28 | Okiセミコンダクタ株式会社 | 降圧電源装置 |
| DE102004045296A1 (de) | 2004-09-16 | 2006-03-23 | Röhm GmbH & Co. KG | Verwendung von Polyalkyl (meth) acrylat-Perlpolymerisaten und Formmasse zur Herstellung von extrudierten Formteilen mit mattierter Oberfläche |
| EP1874274A2 (en) | 2005-04-06 | 2008-01-09 | Mallinckrodt Inc. | Matrix-based pulse release pharmaceutical formulation |
| EP2209455A1 (en) * | 2007-10-15 | 2010-07-28 | Glaxo Group Limited | Paneled capsule shells for release of pharmaceutical compositions |
| CN101827573A (zh) * | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 已装填的连接件的制造装置和方法 |
| JP2011500626A (ja) * | 2007-10-15 | 2011-01-06 | グラクソ グループ リミテッド | 1種または複数の物質を段階的に放出させるためのマルチパートカプセル |
| CN101827571A (zh) * | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 用于释放一种或多种药物成分的多部分剂型的连接件及所得剂型 |
| EP2219624A2 (en) * | 2007-11-08 | 2010-08-25 | Glaxo Group Limited | Pharmaceutical formulations |
| JP2012502883A (ja) * | 2008-06-13 | 2012-02-02 | グラクソ グループ リミテッド | 医薬製剤 |
-
2005
- 2005-03-10 TW TW094107228A patent/TW200539903A/zh unknown
- 2005-03-10 PE PE2005000274A patent/PE20060003A1/es not_active Application Discontinuation
- 2005-03-10 AR ARP050100929A patent/AR048033A1/es unknown
- 2005-03-10 TW TW101112145A patent/TW201240679A/zh unknown
- 2005-03-11 US US10/598,810 patent/US20070178156A1/en not_active Abandoned
- 2005-03-11 WO PCT/US2005/008147 patent/WO2005089726A1/en not_active Ceased
- 2005-03-11 CN CN200580015367XA patent/CN1953739B/zh not_active Expired - Fee Related
- 2005-03-11 JP JP2007503046A patent/JP2007528901A/ja not_active Ceased
- 2005-03-11 BR BRPI0508342-7A patent/BRPI0508342A/pt not_active IP Right Cessation
- 2005-03-11 NZ NZ549264A patent/NZ549264A/en unknown
- 2005-03-11 AU AU2005222612A patent/AU2005222612C1/en not_active Ceased
- 2005-03-11 CA CA002559227A patent/CA2559227A1/en not_active Abandoned
- 2005-03-11 KR KR1020067018523A patent/KR101242988B1/ko not_active Expired - Fee Related
- 2005-03-11 US US11/078,077 patent/US8147871B2/en not_active Expired - Fee Related
- 2005-03-11 RU RU2006136020/15A patent/RU2447885C2/ru not_active IP Right Cessation
- 2005-03-11 EP EP05727507A patent/EP1729744A4/en not_active Withdrawn
- 2005-03-11 KR KR1020127031532A patent/KR20130010511A/ko not_active Ceased
- 2005-03-11 KR KR1020127004334A patent/KR20120044365A/ko not_active Ceased
-
2006
- 2006-08-17 IL IL177566A patent/IL177566A/en not_active IP Right Cessation
- 2006-09-27 MA MA29346A patent/MA28489B1/fr unknown
- 2006-10-10 NO NO20064570A patent/NO20064570L/no not_active Application Discontinuation
-
2011
- 2011-07-06 RU RU2011127852/15A patent/RU2011127852A/ru not_active Application Discontinuation
- 2011-11-30 JP JP2011262441A patent/JP2012097088A/ja not_active Withdrawn
-
2012
- 2012-01-31 US US13/362,429 patent/US20120196940A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007528901A5 (enExample) | ||
| JP2011503048A5 (enExample) | ||
| JP2006528197A5 (enExample) | ||
| JP5390014B2 (ja) | 抗凝固剤の溶出改善方法 | |
| RU2006136020A (ru) | Фармацевтические композиции | |
| US9861585B2 (en) | Osmotic floating tablets | |
| JP2017500332A (ja) | 経口医薬組成物 | |
| JP2014501267A (ja) | メサラジン制御放出用の経口用医薬錠剤および前記錠剤を得るための製法 | |
| JP2008163038A5 (enExample) | ||
| JP2006503023A (ja) | スタチン薬物の放出調節ための医薬品製剤および方法 | |
| CN116327781A (zh) | 阿法比星制剂及其制备方法 | |
| CN101820866B (zh) | 用于固体剂型的机械保护层 | |
| JP2017222645A (ja) | 腸溶性被覆顆粒の耐酸性が改善された圧縮成形錠剤 | |
| EP2661260A2 (en) | Modified release benzimidazole formulations | |
| WO2016101024A1 (en) | Method of treatment | |
| JP2017501972A5 (enExample) | ||
| JP2008503540A5 (enExample) | ||
| JP6816972B2 (ja) | エゼチミブ含有医薬組成物及びその製造方法、エゼチミブ含有医薬組成物の硬度低下抑制剤及び硬度低下抑制方法、並びにエゼチミブ含有医薬組成物の吸湿抑制剤及び吸湿抑制方法 | |
| WO2016147108A1 (en) | Pharmaceutical compositions of dimethyl fumarate | |
| WO2016012898A1 (en) | Oral pharmaceutical composition of lurasidone | |
| AU2013356926B2 (en) | 5-aminosalicylic acid capsule formulation | |
| JP2019034914A (ja) | 良好な徐放性を有する、レボドパ含有小型化錠剤 | |
| JP2020055756A (ja) | 腸溶性顆粒及びこれを含有する腸溶性製剤 | |
| JP6824549B2 (ja) | 経口固形製剤およびその製造法 | |
| JP2019156723A (ja) | 圧縮成形性に優れた賦形剤を用いる、浸透膨潤型口腔内崩壊錠 |