|
PT72786B
(en)
|
1980-04-03 |
1983-01-10 |
Biogen Nv |
Process for producing dna sequences recombinant dna molecules and human fibroplast interferon-like polypeptides
|
|
IT1185503B
(it)
*
|
1984-01-11 |
1987-11-12 |
Univ New York |
Cloni di odna di eritropietina umana
|
|
IL77081A
(en)
*
|
1984-12-04 |
1999-10-28 |
Genetics Inst |
Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin
|
|
JPS62501010A
(ja)
|
1984-12-04 |
1987-04-23 |
ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド |
エリトロポエチンの生産方法
|
|
US4677195A
(en)
*
|
1985-01-11 |
1987-06-30 |
Genetics Institute, Inc. |
Method for the purification of erythropoietin and erythropoietin compositions
|
|
US4732889A
(en)
*
|
1985-02-06 |
1988-03-22 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis
|
|
US4745099A
(en)
*
|
1985-02-06 |
1988-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for the treatment of the anemia of malignant tumors
|
|
GB2177914B
(en)
*
|
1985-06-04 |
1989-10-25 |
Chugai Pharmaceutical Co Ltd |
A pharmaceutical composition containing human erythropoietin and a surface active agent for nasal administration for the treatment of anemia
|
|
IL79176A
(en)
*
|
1985-06-20 |
1992-06-21 |
Kirin Amgen Inc |
Process for the recovery of erythropoietin from a fluid
|
|
JPS63500636A
(ja)
*
|
1985-08-23 |
1988-03-10 |
麒麟麦酒株式会社 |
多分化能性顆粒球コロニー刺激因子をコードするdna
|
|
US4810643A
(en)
*
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
|
US6004548A
(en)
|
1985-08-23 |
1999-12-21 |
Amgen, Inc. |
Analogs of pluripotent granulocyte colony-stimulating factor
|
|
US4935350A
(en)
*
|
1985-11-18 |
1990-06-19 |
Amgen |
Materials and methods for controlling plasmid copy number and stability
|
|
JPS62171696A
(ja)
*
|
1986-01-23 |
1987-07-28 |
Sumitomo Chem Co Ltd |
ヒトエリスロポエチンの製造方法
|
|
EP0236059B1
(en)
*
|
1986-02-27 |
1994-04-27 |
Snow Brand Milk Products Co. Ltd. |
Preparation of erythropoietin-producing cells and production process of erythropoietin using same
|
|
DK173067B1
(da)
*
|
1986-06-27 |
1999-12-13 |
Univ Washington |
Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa
|
|
GR871029B
(en)
|
1986-07-14 |
1987-11-02 |
Genetics Inst |
Novel osteoinductive factors
|
|
US4954437A
(en)
*
|
1986-09-15 |
1990-09-04 |
Integrated Genetics, Inc. |
Cell encoding recombinant human erythropoietin
|
|
US5013718A
(en)
*
|
1986-11-21 |
1991-05-07 |
Amgen, Inc. |
Method for treating iron overload using EPO
|
|
WO1988005466A2
(en)
*
|
1987-01-15 |
1988-07-28 |
Codon |
Tandem gene eukaryotic expression vectors
|
|
US4835260A
(en)
*
|
1987-03-20 |
1989-05-30 |
Genetics Institute, Inc. |
Erythropoietin composition
|
|
JP2791418B2
(ja)
|
1987-12-02 |
1998-08-27 |
株式会社ミドリ十字 |
異種蛋白質の製造方法、組換えdna、形質転換体
|
|
DE3923963A1
(de)
*
|
1989-07-20 |
1991-01-31 |
Behringwerke Ag |
Muteine des menschlichen erythropoetins, ihre herstellung und ihre verwendung
|
|
DE3924746A1
(de)
*
|
1989-07-26 |
1991-01-31 |
Behringwerke Ag |
Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper
|
|
US6932968B1
(en)
|
1989-07-26 |
2005-08-23 |
Dade Behring Marburg Gmbh |
Erythropoietin (EPO) peptides and antibodies directed against these
|
|
KR100263845B1
(ko)
*
|
1989-10-13 |
2000-08-16 |
스튜어트 엘.왓트 |
에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물
|
|
US7217689B1
(en)
|
1989-10-13 |
2007-05-15 |
Amgen Inc. |
Glycosylation analogs of erythropoietin
|
|
DE4115722A1
(de)
*
|
1991-05-14 |
1992-11-19 |
Boehringer Mannheim Gmbh |
Serumfreies medium zur kultivierung von saeugerzellen
|
|
US5968502A
(en)
*
|
1991-11-05 |
1999-10-19 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
|
US6270989B1
(en)
|
1991-11-05 |
2001-08-07 |
Transkaryotic Therapies, Inc. |
Protein production and delivery
|
|
NZ245015A
(en)
*
|
1991-11-05 |
1995-12-21 |
Transkaryotic Therapies Inc |
Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
|
|
US5728536A
(en)
*
|
1993-07-29 |
1998-03-17 |
St. Jude Children's Research Hospital |
Jak kinases and regulation of Cytokine signal transduction
|
|
FR2686899B1
(fr)
*
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
US6531124B1
(en)
|
1992-07-10 |
2003-03-11 |
Transkaryotic Therapies, Inc. |
In vivo production and delivery of insulinotropin for gene therapy
|
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
|
WO1994005679A1
(fr)
*
|
1992-09-09 |
1994-03-17 |
Nippon Kayaku Kabushiki Kaisha |
Nouvelle substance physiologiquement active appelee nk175203, son procede de production et son utilisation pharmaceutique
|
|
WO1994024160A2
(en)
*
|
1993-04-21 |
1994-10-27 |
Brigham And Women's Hospital |
Erythropoietin muteins with enhanced activity
|
|
IL192290A0
(en)
*
|
1993-08-17 |
2008-12-29 |
Kirin Amgen Inc |
Erythropoietin analogs
|
|
US8192955B1
(en)
*
|
1994-01-03 |
2012-06-05 |
Genentech, Inc. |
Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
|
|
US5888774A
(en)
*
|
1994-12-19 |
1999-03-30 |
Cangene Corporation |
Recombinant DNA molecules and expression vectors for erythropoietin
|
|
IL118201A
(en)
*
|
1995-05-11 |
2004-12-15 |
Roche Diagnostics Gmbh |
Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
|
|
KR100459984B1
(ko)
*
|
1995-06-07 |
2005-06-20 |
아피맥스 테크놀로지스, 엔.브이. |
에리트로포이에틴수용체(epo-r)에결합하는화합물및펩티드
|
|
EP0833934B2
(en)
|
1995-06-15 |
2012-08-15 |
Crucell Holland B.V. |
Packaging systems for human recombinant adenovirus to be used in gene therapy
|
|
EP0752474A1
(en)
*
|
1995-07-07 |
1997-01-08 |
Boehringer Mannheim Gmbh |
Nucleic acid coding for CMP-N-acetyl-neuraminic acid hydroxylase and its use for the production of modified glycoproteins
|
|
WO1997003200A1
(en)
*
|
1995-07-07 |
1997-01-30 |
Boehringer Mannheim Gmbh |
Nucleic acid coding for cmp-n-acetyl-neuraminic acid hydroxylase and its use for the production of modified glycoproteins
|
|
KR970010968A
(ko)
*
|
1995-08-24 |
1997-03-27 |
윤원영 |
오리 배 세포를 이용한 에리스로포이틴의 발현 시스템
|
|
ES2206695T3
(es)
|
1996-03-14 |
2004-05-16 |
Genentech, Inc. |
Receptor de gdnf y utiolizacion del mismo.
|
|
GB2318352A
(en)
*
|
1996-06-25 |
1998-04-22 |
Dejan Markovic |
Polypeptides mimicking the activity of human erythropoietin
|
|
US5952226A
(en)
*
|
1996-11-05 |
1999-09-14 |
Modex Therapeutiques |
Hypoxia responsive EPO producing cells
|
|
AU753701B2
(en)
*
|
1997-04-21 |
2002-10-24 |
Glycozyme, Inc. |
Determination of recombinant glycosylated proteins and peptides in biological fluids
|
|
US6475725B1
(en)
|
1997-06-20 |
2002-11-05 |
Baxter Aktiengesellschaft |
Recombinant cell clones having increased stability and methods of making and using the same
|
|
US6187564B1
(en)
*
|
1997-07-10 |
2001-02-13 |
Beth Israel Deaconess Medical Center |
DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
|
|
DE19729769A1
(de)
|
1997-07-11 |
1999-01-14 |
Cardiogene Gentherapeutische S |
Transfektionssystem, seine Herstellung und Verwendung in der somatischen Gentherapie
|
|
US6017876A
(en)
*
|
1997-08-15 |
2000-01-25 |
Amgen Inc. |
Chemical modification of granulocyte-colony stimulating factor (G-CSF) bioactivity
|
|
US6740503B1
(en)
|
1997-09-26 |
2004-05-25 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
|
US6897066B1
(en)
*
|
1997-09-26 |
2005-05-24 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
|
PT1023442E
(pt)
*
|
1997-10-16 |
2011-02-25 |
Synageva Biopharma Corp |
Vectores compreendendo um promotor específico do magno para transgénese aviária
|
|
CA2693296C
(en)
*
|
1997-12-08 |
2013-09-10 |
Merck Patent Gmbh |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
|
RU2125093C1
(ru)
*
|
1998-02-12 |
1999-01-20 |
Государственный научно-исследовательский институт особо чистых биопрепаратов |
Способ получения рекомбинантного человеческого эритропоэтина, штамм культивируемых клеток яичника китайского хомяка - продуцент эритропоэтина
|
|
US7037663B2
(en)
*
|
1998-02-19 |
2006-05-02 |
Eastern Virginia Medical School |
Human zona pellucida protein 3 and uses thereof
|
|
EP1056858B1
(en)
*
|
1998-02-19 |
2004-12-08 |
Eastern Virginia Medical School |
RECOMBINANT ACTIVE HUMAN ZONA PELLUCIDA PROTEIN 3 (hZP3)
|
|
ES2224299T3
(es)
|
1998-02-23 |
2005-03-01 |
Cilag Ag International |
Dispersion liposomal de eritroyetina.
|
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
|
KR100434729B1
(ko)
*
|
1998-03-18 |
2004-11-03 |
주식회사 엘지생명과학 |
천연 추출물을 첨가하여 중국햄스터 난소 유래세포에서 에리스로포이에틴의 생산 증대방법
|
|
JP2002509729A
(ja)
*
|
1998-03-27 |
2002-04-02 |
サイトス バイオテクノロジー アーゲー |
誘導性のアルファウイルス遺伝子発現系
|
|
AR019025A1
(es)
|
1998-04-09 |
2001-12-26 |
Roche Diagnostics Gmbh |
Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado
|
|
MXPA00010070A
(es)
*
|
1998-04-15 |
2004-03-10 |
Lexigen Pharm Corp |
Mejora de respuestas inmunes medidas de proteina de fusion anticuerpo-citoquina por co-administracion con inhibidor de angiogenesis.
|
|
US6696411B1
(en)
*
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
|
EP1071795A4
(en)
|
1998-04-22 |
2005-01-19 |
Cornell Res Foundation Inc |
CANINE ERITHROPOIETINE GENE AND RECOMBINANT PROTEIN
|
|
WO1999066054A2
(en)
|
1998-06-15 |
1999-12-23 |
Genzyme Transgenics Corp. |
Erythropoietin analog-human serum albumin fusion protein
|
|
US20050181482A1
(en)
*
|
2004-02-12 |
2005-08-18 |
Meade Harry M. |
Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
|
|
US6541033B1
(en)
|
1998-06-30 |
2003-04-01 |
Amgen Inc. |
Thermosensitive biodegradable hydrogels for sustained delivery of leptin
|
|
EP1100545A4
(en)
*
|
1998-07-29 |
2002-03-20 |
Invitrogen Corp |
REGULATED EXPRESSION OF RECOMBINANT PROTEINS USING RNA VIRUSES
|
|
EP0984062A1
(en)
*
|
1998-09-04 |
2000-03-08 |
Cytos Biotechnology AG |
Production of human erythropoietin
|
|
US6420339B1
(en)
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
|
US7304150B1
(en)
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
BR9917606A
(pt)
|
1998-11-06 |
2002-12-31 |
Bio Sidus S A |
Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
|
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
|
BR9905867A
(pt)
*
|
1998-11-06 |
2001-01-23 |
Bio Sidus S A |
Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
|
|
BR9905868A
(pt)
|
1998-11-06 |
2001-01-23 |
Bio Sidus S A |
Procedimento de cultivo massivo de células de mamìfero para a obtenção de eritropoetina humana, recombinante e a eritropoetina humana recombinante obtida com tal procedimento
|
|
DE19857609A1
(de)
|
1998-12-14 |
2000-06-15 |
Hannelore Ehrenreich |
Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
|
|
US6245740B1
(en)
|
1998-12-23 |
2001-06-12 |
Amgen Inc. |
Polyol:oil suspensions for the sustained release of proteins
|
|
US6451346B1
(en)
*
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
US7345019B1
(en)
*
|
1999-04-13 |
2008-03-18 |
The Kenneth S. Warren Institute, Inc. |
Modulation of excitable tissue function by peripherally administered erythropoietin
|
|
US7309687B1
(en)
|
1999-04-13 |
2007-12-18 |
The Kenneth S. Warren Institute, Inc. |
Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin
|
|
US7604960B2
(en)
*
|
1999-04-15 |
2009-10-20 |
Crucell Holland B.V. |
Transient protein expression methods
|
|
US20050164386A1
(en)
*
|
1999-04-15 |
2005-07-28 |
Uytdehaag Alphonsus G. |
Overexpression of enzymes involved in post-translational protein modifications in human cells
|
|
US20050170463A1
(en)
*
|
1999-04-15 |
2005-08-04 |
Abraham Bout |
Recombinant protein production in permanent amniocytic cells that comprise nucleic acid encoding adenovirus E1A and E1B proteins
|
|
US7297680B2
(en)
|
1999-04-15 |
2007-11-20 |
Crucell Holland B.V. |
Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
|
|
US8236561B2
(en)
*
|
1999-04-15 |
2012-08-07 |
Crucell Holland B.V. |
Efficient production of IgA in recombinant mammalian cells
|
|
US6855544B1
(en)
*
|
1999-04-15 |
2005-02-15 |
Crucell Holland B.V. |
Recombinant protein production in a human cell
|
|
AU766507B2
(en)
*
|
1999-05-07 |
2003-10-16 |
Genentech Inc. |
Novel chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
US6555343B1
(en)
|
1999-05-07 |
2003-04-29 |
Genentech Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
US6831060B2
(en)
|
1999-05-07 |
2004-12-14 |
Genentech, Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
|
AT409379B
(de)
|
1999-06-02 |
2002-07-25 |
Baxter Ag |
Medium zur protein- und serumfreien kultivierung von zellen
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US6737519B1
(en)
*
|
1999-07-30 |
2004-05-18 |
Genome Therapeutics Corporation |
Human genes relating to respiratory diseases and obesity
|
|
HUP0202442A3
(en)
*
|
1999-08-09 |
2005-01-28 |
Lexigen Pharmaceuticals Corp L |
Multiple cytokine-antibody complexes
|
|
US8106098B2
(en)
*
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
|
AU2154401A
(en)
|
1999-11-12 |
2001-05-30 |
Merck Patent Gmbh |
Erythropoietin forms with improved properties
|
|
US20050202538A1
(en)
*
|
1999-11-12 |
2005-09-15 |
Merck Patent Gmbh |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
|
US6703480B1
(en)
|
1999-11-24 |
2004-03-09 |
Palani Balu |
Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
|
|
US7521220B2
(en)
*
|
1999-11-26 |
2009-04-21 |
Crucell Holland B.V. |
Production of vaccines
|
|
US7527961B2
(en)
*
|
1999-11-26 |
2009-05-05 |
Crucell Holland B.V. |
Production of vaccines
|
|
US7192759B1
(en)
|
1999-11-26 |
2007-03-20 |
Crucell Holland B.V. |
Production of vaccines
|
|
WO2001042442A2
(en)
|
1999-12-10 |
2001-06-14 |
Cytos Biotechnology Ag |
Activation of endogenous genes by genomic introduction of a replicon
|
|
DK1252192T3
(da)
*
|
2000-02-11 |
2006-11-20 |
Merck Patent Gmbh |
Forbedring af antistofbaserede fusionsproteiners serumhalveringstid
|
|
EP1274720A4
(en)
|
2000-04-12 |
2004-08-18 |
Human Genome Sciences Inc |
ALBUMIN FUSED PROTEINS
|
|
US20050100991A1
(en)
*
|
2001-04-12 |
2005-05-12 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
IES20010462A2
(en)
*
|
2000-05-12 |
2001-11-14 |
Cyril John Higgins |
Use of the world wide web
|
|
DK1294401T3
(da)
*
|
2000-06-29 |
2007-10-08 |
Merck Patent Gmbh |
Forbedring af antistof/cytokin-fusionsproteinmedierede immunresponser ved kombineret behandling med immuncytokin-optagelsesforberende midler
|
|
US20020012982A1
(en)
*
|
2000-07-13 |
2002-01-31 |
Invitrogen Corporation |
Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
|
|
US7855229B2
(en)
*
|
2000-08-24 |
2010-12-21 |
University Of Tennessee Research Foundation |
Treating wasting disorders with selective androgen receptor modulators
|
|
US7919647B2
(en)
|
2000-08-24 |
2011-04-05 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
|
US7622503B2
(en)
|
2000-08-24 |
2009-11-24 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
|
US7645898B2
(en)
*
|
2000-08-24 |
2010-01-12 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and method of use thereof
|
|
ATE428790T1
(de)
|
2000-09-25 |
2009-05-15 |
Genetronics Inc |
Verbessertes system zur regulation der transgenexpression
|
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
KR100645843B1
(ko)
|
2000-12-20 |
2006-11-14 |
에프. 호프만-라 로슈 아게 |
에리트로포이에틴 접합체
|
|
US20030072737A1
(en)
*
|
2000-12-29 |
2003-04-17 |
Michael Brines |
Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
|
|
US6531121B2
(en)
|
2000-12-29 |
2003-03-11 |
The Kenneth S. Warren Institute, Inc. |
Protection and enhancement of erythropoietin-responsive cells, tissues and organs
|
|
US7767643B2
(en)
*
|
2000-12-29 |
2010-08-03 |
The Kenneth S. Warren Institute, Inc. |
Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
|
|
KR100399337B1
(ko)
*
|
2001-02-07 |
2003-09-26 |
드림바이오젠 주식회사 |
단백질의 무세포 번역후수식법
|
|
MXPA03008031A
(es)
|
2001-03-07 |
2003-12-04 |
Merck Patent Gmbh |
Tecnologia de expresion para proteinas que contienen porcion de anticuerpo isotipo hibrida.
|
|
DE10112825A1
(de)
|
2001-03-16 |
2002-10-02 |
Fresenius Kabi De Gmbh |
HESylierung von Wirkstoffen in wässriger Lösung
|
|
WO2002079415A2
(en)
*
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
|
CN100503639C
(zh)
|
2001-05-03 |
2009-06-24 |
默克专利有限公司 |
重组肿瘤特异性抗体及其应用
|
|
AU2002310122A1
(en)
*
|
2001-05-25 |
2002-12-09 |
Human Genome Sciences, Inc. |
Chemokine beta-1 fusion proteins
|
|
US7148021B2
(en)
*
|
2001-08-02 |
2006-12-12 |
Eastern Virginia Meical School |
Human zona pellucida proteins and methods of their use in diagnosing male infertility
|
|
WO2003018782A2
(en)
*
|
2001-08-30 |
2003-03-06 |
Stem Cell Therapeutics Inc. |
Differentiation of neural stem cells and therapeutic use theeof
|
|
US20030104996A1
(en)
*
|
2001-08-30 |
2003-06-05 |
Tiansheng Li |
L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
|
|
US7393830B2
(en)
*
|
2001-09-14 |
2008-07-01 |
Stem Cell Therapeutics Inc. |
Prolactin induced increase in neural stem cell numbers
|
|
EP1430113A2
(en)
*
|
2001-09-18 |
2004-06-23 |
Stem Cell Therapeutics Inc. |
Effect of growth hormone and igf-1 on neural stem cells and therapeutic application
|
|
PL368749A1
(en)
*
|
2001-11-28 |
2005-04-04 |
Sandoz Ag |
Cell culture process
|
|
BR0214650A
(pt)
*
|
2001-12-04 |
2005-05-03 |
Merck Patent Gmbh |
Imunocitoquinas com seletividade modulada
|
|
US8853266B2
(en)
|
2001-12-06 |
2014-10-07 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators for treating diabetes
|
|
US20070161608A1
(en)
*
|
2001-12-06 |
2007-07-12 |
Dalton James T |
Selective androgen receptor modulators for treating muscle wasting
|
|
ATE384785T1
(de)
*
|
2001-12-07 |
2008-02-15 |
Crucell Holland Bv |
Herstellung von viren, virusisolaten, und impfstoffen
|
|
WO2005003296A2
(en)
|
2003-01-22 |
2005-01-13 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
CA2841097A1
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin and g-csf fusion proteins
|
|
WO2003059934A2
(en)
*
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
AU2003226960B2
(en)
|
2002-01-17 |
2007-11-22 |
Lonza Biologics Plc. |
Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium
|
|
DE10209822A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
|
US20030191056A1
(en)
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
|
CA2485365A1
(en)
*
|
2002-05-13 |
2003-11-20 |
Modigenetech Ltd. |
Ctp-extended erythropoietin
|
|
EA010200B1
(ru)
*
|
2002-07-01 |
2008-06-30 |
Дзе Кеннет С. Уоррен Инститьют, Инк. |
Рекомбинантные тканезащитные цитокины и кодирующие их нуклеиновые кислоты для защиты, восстановления и усиления чувствительных клеток, тканей и органов
|
|
EP2287288B1
(en)
|
2002-07-09 |
2012-11-07 |
Baxter International Inc. |
Animal protein free media for cultivation of cells
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
CA2492442A1
(en)
*
|
2002-07-31 |
2004-02-05 |
Stem Cell Therapeutics Inc. |
Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
|
|
KR100521309B1
(ko)
*
|
2002-08-31 |
2005-10-14 |
씨제이 주식회사 |
당쇄화된 인간 과립구 형성인자
|
|
CA2498319A1
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
|
DE20321793U1
(de)
|
2002-09-11 |
2010-06-02 |
Fresenius Kabi Deutschland Gmbh |
Hydroxyalkylstärke-Derivate
|
|
EP1681303B1
(en)
|
2002-09-11 |
2013-09-04 |
Fresenius Kabi Deutschland GmbH |
HASylated polypeptides, especially HASylated erythropoietin
|
|
PL217085B1
(pl)
|
2002-09-11 |
2014-06-30 |
Fresenius Kabi Gmbh |
Koniugat hydroksyalkiloskrobi i polipeptydu, sposób wytwarzania koniugatu hydroksyalkiloskrobi i polipeptydu, zastosowanie koniugatu hydroksyalkiloskrobi i polipeptydu oraz kompozycja farmaceutyczna koniugatu hydroksyalkiloskrobi i polipeptydu
|
|
EP1549350B1
(en)
|
2002-10-08 |
2008-09-24 |
Fresenius Kabi Deutschland GmbH |
Pharmaceutically active oligosaccharide conjugates
|
|
EP1572748B1
(en)
*
|
2002-12-17 |
2010-06-23 |
MERCK PATENT GmbH |
Humanized antibody (h14.18) of the mouse 14.18 antibody binding to gd2 and its fusion with il-2
|
|
ZA200506196B
(en)
*
|
2003-02-03 |
2006-10-25 |
Japan Immuno Inc |
High-expression vector for animal cells
|
|
EP1624883A4
(en)
*
|
2003-04-09 |
2008-11-26 |
Univ Utah Res Found |
COMPOSITIONS AND METHODS RELATING TO THE PRODUCTION OF ERYTHROPOIETIN
|
|
US7459152B2
(en)
*
|
2003-04-23 |
2008-12-02 |
Rush University Medical Center |
Erythropoietin administration to improve graft survival
|
|
CA2520891C
(en)
|
2003-05-09 |
2014-07-08 |
Crucell Holland B.V. |
Cultures of e1-immortalized cells and processes for culturing the same to increase product yields therefrom
|
|
WO2004101600A2
(en)
*
|
2003-05-12 |
2004-11-25 |
Affymax, Inc. |
Novel poly(ethylene glycol) modified compounds and uses thereof
|
|
PL1629007T3
(pl)
*
|
2003-05-12 |
2009-09-30 |
Affymax Inc |
Nowe peptydy wiążące się z receptorem erytropoetyny
|
|
PL1625156T3
(pl)
*
|
2003-05-12 |
2013-03-29 |
Affymax Inc |
Peptydy wiążące się do receptora erytropoetyny
|
|
EP1628686A2
(en)
*
|
2003-05-12 |
2006-03-01 |
Affymax, Inc. |
Spacer moiety for poly (ethylene glycol)-modified peptides
|
|
AU2004240782B2
(en)
*
|
2003-05-23 |
2011-04-21 |
Crucell Holland B.V. |
Production of recombinant IGM in per.C6 cells
|
|
CA2528988C
(en)
|
2003-06-10 |
2012-05-01 |
Lg Life Sciences Ltd. |
Stable, aqueous solution of human erythropoietin, not containing serum albumin
|
|
EP2216415B2
(en)
*
|
2003-08-01 |
2017-01-04 |
Life Technologies Corporation |
Methods for preparing short RNA molecules
|
|
WO2005014655A2
(en)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
|
US7645733B2
(en)
|
2003-09-29 |
2010-01-12 |
The Kenneth S. Warren Institute, Inc. |
Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions
|
|
DE502004011252D1
(de)
|
2003-12-30 |
2010-07-15 |
Augustinus Bader |
Verwendung des erythropoietins zur regeneration von lebergewebe
|
|
EP1711159B1
(en)
|
2003-12-30 |
2013-03-20 |
Durect Corporation |
Solid implants containing a block copolymer for controlled release of a gnrh compound
|
|
CA2551916C
(en)
*
|
2003-12-31 |
2014-04-29 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
|
DE102004004509B4
(de)
|
2004-01-23 |
2010-07-01 |
Epoplus Gmbh Co.Kg |
Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden
|
|
US7846898B2
(en)
*
|
2004-02-13 |
2010-12-07 |
Stem Cell Therapeutics Corp. |
Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
|
|
US7255288B2
(en)
*
|
2004-03-08 |
2007-08-14 |
Wan Shan Chan |
Aroma therapy for fountain
|
|
JP5396019B2
(ja)
|
2004-03-11 |
2014-01-22 |
フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
ヒドロキシアルキルデンプンとタンパク質とのコンジュゲート
|
|
CN1946742A
(zh)
|
2004-03-11 |
2007-04-11 |
弗雷泽纽斯卡比德国有限公司 |
通过还原氨基化制备的羟烷基淀粉和蛋白质的偶联物
|
|
US7588745B2
(en)
*
|
2004-04-13 |
2009-09-15 |
Si Options, Llc |
Silicon-containing products
|
|
US9889110B2
(en)
|
2004-06-07 |
2018-02-13 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator for treating hormone-related conditions
|
|
US20110237664A1
(en)
*
|
2004-06-07 |
2011-09-29 |
Dalton James T |
Selective androgen receptor modulators for treating diabetes
|
|
US9884038B2
(en)
|
2004-06-07 |
2018-02-06 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator and methods of use thereof
|
|
US20060094104A1
(en)
|
2004-10-29 |
2006-05-04 |
Leopold Grillberger |
Animal protein-free media for cultivation of cells
|
|
US20090005292A1
(en)
*
|
2004-11-11 |
2009-01-01 |
Affymax, Inc. |
Novel Peptides that Bind to the Erythropoietin Receptor
|
|
WO2006062685A2
(en)
*
|
2004-11-11 |
2006-06-15 |
Affymax, Inc. |
Novel peptides that bind to the erythropoietin receptor
|
|
WO2006061853A2
(en)
*
|
2004-12-10 |
2006-06-15 |
Serum Institute Of India Limited |
Novel erythropoietic compounds and a process for producing erythropoietic compounds
|
|
WO2006089228A2
(en)
*
|
2005-02-16 |
2006-08-24 |
Nektar Therapeutics Al, Corporation |
Conjugates of an epo moiety and a polymer
|
|
US8324159B2
(en)
*
|
2005-06-03 |
2012-12-04 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
|
US7919461B2
(en)
|
2005-06-03 |
2011-04-05 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
|
US7550433B2
(en)
*
|
2005-06-03 |
2009-06-23 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
|
ES2453981T3
(es)
|
2005-08-31 |
2014-04-09 |
University Of Tennessee Research Foundation |
Tratamiento de síntomas de enfermedad renal con moduladores selectivos de receptor de andrógenos (SARM)
|
|
EP1762250A1
(en)
|
2005-09-12 |
2007-03-14 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
|
|
AU2006297041A1
(en)
|
2005-09-27 |
2007-04-05 |
Stem Cell Therapeutics Corp. |
Oligodendrocyte precursor cell proliferation regulated by prolactin
|
|
US9388382B2
(en)
*
|
2005-10-05 |
2016-07-12 |
The Board Of Trustees Of The University Of Illinois |
Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
|
|
WO2008048671A1
(en)
*
|
2006-10-18 |
2008-04-24 |
University Of Illinois |
Embryonic-like stem cells derived from adult human peripheral blood and methods of use
|
|
EP1966237A2
(en)
*
|
2005-11-24 |
2008-09-10 |
Laboratoires Serono SA |
Erythropoietin polypeptides and uses thereof
|
|
US7972810B2
(en)
†
|
2005-12-08 |
2011-07-05 |
Amgen Inc. |
Production of glycoproteins using manganese
|
|
WO2007077217A2
(en)
|
2006-01-04 |
2007-07-12 |
Baxter International Inc. |
Oligopeptide-free cell culture media
|
|
DE102006004008A1
(de)
|
2006-01-27 |
2007-08-02 |
Hannelore Prof. Dr. Dr. Ehrenreich |
Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
|
|
US7625564B2
(en)
|
2006-01-27 |
2009-12-01 |
Novagen Holding Corporation |
Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
|
|
EP2004212A4
(en)
*
|
2006-03-17 |
2010-07-14 |
Stem Cell Therapeutics Corp |
CONTINUOUS DOSING SCHEMES FOR NEURAL STEM CELL PROLIFERATING AGENTS AND NEURAL STEM CELL DIFFERENTIATING AGENTS
|
|
EP1997505A4
(en)
|
2006-03-22 |
2013-02-13 |
Chugai Pharmaceutical Co Ltd |
PREPARATION OF ERYTHROPOIETIN SOLUTION
|
|
CN101062407A
(zh)
|
2006-04-29 |
2007-10-31 |
中国科学院上海生命科学研究院 |
促红细胞生成素在预防或治疗视网膜损伤中的用途
|
|
KR101460693B1
(ko)
|
2006-07-12 |
2014-11-17 |
유니버시티 오브 테네시 리서치 파운데이션 |
치환된 아실아닐리드 및 그의 사용 방법
|
|
DK2054074T3
(da)
|
2006-08-04 |
2014-11-03 |
Prolong Pharmaceuticals Llc |
Modificeret erythropoietin
|
|
JPWO2008023725A1
(ja)
|
2006-08-22 |
2010-01-14 |
中外製薬株式会社 |
末梢神経障害の予防および/または治療剤
|
|
CN101528214B
(zh)
|
2006-08-24 |
2013-06-05 |
田纳西大学研究基金会 |
取代的n-酰基苯胺及其使用方法
|
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
|
KR101470472B1
(ko)
*
|
2006-09-14 |
2014-12-09 |
메드제닉스 메디칼 이스라엘 리미티드 |
장기 지속형 약물 제형
|
|
KR101248252B1
(ko)
|
2006-11-28 |
2013-03-27 |
한올바이오파마주식회사 |
변형된 에리스로포이에틴 폴리펩티드와 이의 치료용 용도
|
|
EP2089424B1
(en)
*
|
2006-12-06 |
2015-07-01 |
JCR PHARMACEUTICALS Co., LTD. |
Method for production of human erythropoietin
|
|
EP2121017A2
(en)
*
|
2006-12-19 |
2009-11-25 |
Nokad |
Method for inhibiting the expression of endogenous erythropoietin (epo)
|
|
MX2009008104A
(es)
*
|
2007-02-02 |
2009-08-07 |
Amgen Inc |
Hepcidina, antagonistas de hepcidina y metodos de uso.
|
|
AR065613A1
(es)
|
2007-03-09 |
2009-06-17 |
Chugai Pharmaceutical Co Ltd |
Agentes de proteccion para organos transplantados
|
|
US20080260820A1
(en)
*
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
|
US20100172919A1
(en)
|
2007-06-15 |
2010-07-08 |
Jan Grimm |
Noveltreatment for neurological disorders
|
|
WO2009010107A1
(en)
|
2007-07-19 |
2009-01-22 |
Hannelore Ehrenreich |
Use of epo receptor activation or stimulation for the improvement of the edss score in patients with multiple sclerosis
|
|
CA2720628A1
(en)
|
2007-07-26 |
2009-01-29 |
Novagen Holding Corporation |
Fusion proteins having mutated immunoglobulin hinge region
|
|
US7968603B2
(en)
|
2007-09-11 |
2011-06-28 |
University Of Tennessee Research Foundation |
Solid forms of selective androgen receptor modulators
|
|
EP2205280B1
(en)
*
|
2007-09-27 |
2019-09-04 |
Amgen Inc. |
Pharmaceutical formulations
|
|
ES2962777T3
(es)
|
2007-11-15 |
2024-03-21 |
Amgen Inc |
Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral
|
|
EP2070950A1
(en)
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
|
US9175078B2
(en)
|
2008-01-25 |
2015-11-03 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
|
MX2010008632A
(es)
|
2008-02-08 |
2010-08-30 |
Ambrx Inc |
Leptina-polipeptidos modificados y sus usos.
|
|
US8653249B2
(en)
*
|
2008-02-27 |
2014-02-18 |
Fuso Pharmaceutical Industries, Ltd. |
Expression vector for mass production of foreign gene-derived protein using animal cell and use thereof
|
|
EP2095829A1
(en)
|
2008-02-27 |
2009-09-02 |
LEK Pharmaceuticals D.D. |
Selenium containing modifying agents and conjugates
|
|
JP2011519279A
(ja)
|
2008-05-01 |
2011-07-07 |
アムジエン・インコーポレーテツド |
抗ヘプシジン抗体及び使用の方法
|
|
DE102008002209A1
(de)
|
2008-06-04 |
2009-12-10 |
Evonik Degussa Gmbh |
Verfahren zur Aufreinigung von Erythropoietin
|
|
DE102008002210A1
(de)
|
2008-06-04 |
2009-12-10 |
Evonik Degussa Gmbh |
Verfahren zur fermentativen Herstellung von Erythropoietin
|
|
WO2009155481A1
(en)
*
|
2008-06-20 |
2009-12-23 |
Gtx, Inc. |
Metabolites of selective androgen receptor modulators and methods of use thereof
|
|
US20120172299A1
(en)
|
2008-09-23 |
2012-07-05 |
F. Hoffmann-La Roche Ag |
Purification of erythropoietin
|
|
ES2631915T3
(es)
|
2008-09-26 |
2017-09-06 |
Ambrx, Inc. |
Polipéptidos modificados de eritropoyetina animal y sus usos
|
|
CA3019967A1
(en)
|
2008-11-13 |
2010-05-20 |
The General Hospital Corporation |
Methods and compositions for regulating iron homeostasis by modulation of bmp-6
|
|
DE102008054716A1
(de)
|
2008-12-16 |
2010-06-17 |
Evonik Degussa Gmbh |
Inprozesskontrolle in einem Verfahren zur Herstellung von EPO
|
|
EP2385115B1
(en)
|
2008-12-22 |
2015-09-09 |
National University Corporation Hokkaido University |
Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
|
|
US20100272816A1
(en)
|
2009-04-27 |
2010-10-28 |
Wolfgang Rudinger |
Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient
|
|
MX356669B
(es)
|
2009-05-02 |
2018-06-08 |
Genzyme Corp |
Terapia genica para trastornos neurodegenerativos.
|
|
CN102712688B
(zh)
|
2009-09-23 |
2015-06-24 |
通益制药有限公司 |
重组人红细胞生成素(epo)的纯化方法、由此纯化的epo以及包含纯化的epo的药物组合物
|
|
US9662271B2
(en)
|
2009-10-23 |
2017-05-30 |
Amgen Inc. |
Vial adapter and system
|
|
SG194370A1
(en)
|
2010-06-07 |
2013-11-29 |
Amgen Inc |
Drug delivery device
|
|
WO2011159758A2
(en)
|
2010-06-15 |
2011-12-22 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
|
EP3305315A1
(en)
|
2010-09-28 |
2018-04-11 |
Aegerion Pharmaceuticals, Inc. |
Engineered polypeptides having enhanced duration of action
|
|
CA2831100C
(en)
|
2011-03-31 |
2020-02-18 |
Mark Dominis Holt |
Vial adapter and system
|
|
SI2699293T1
(sl)
|
2011-04-20 |
2019-05-31 |
Amgen Inc. |
Avtoinjekcijski aparat
|
|
EP3045188B1
(en)
|
2011-10-14 |
2020-12-23 |
Amgen Inc. |
Injector and method of assembly
|
|
KR101443257B1
(ko)
*
|
2011-10-18 |
2014-09-19 |
주식회사 종근당 |
낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
|
|
US11707410B2
(en)
|
2011-10-25 |
2023-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US10350139B2
(en)
|
2011-10-25 |
2019-07-16 |
Corning Incorporated |
Pharmaceutical glass packaging assuring pharmaceutical sterility
|
|
RU2717835C2
(ru)
|
2012-07-13 |
2020-03-26 |
Джи Ти Икс, ИНК. |
Способ лечения андроген-рецептор(ar)-положительных форм рака молочной железы с использованием селективных модуляторов андрогенных рецепторов (sarm)
|
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
US9650411B2
(en)
|
2012-08-07 |
2017-05-16 |
Kyowa Hakko Kirin Co., Ltd. |
Method of purifying protein
|
|
EP2906683B1
(en)
|
2012-10-15 |
2017-05-31 |
Bristol-Myers Squibb Company |
Mammalian cell culture processes for protein production
|
|
EP3072548B1
(en)
|
2012-11-21 |
2019-03-06 |
Amgen, Inc |
Drug delivery device
|
|
KR20150127582A
(ko)
|
2013-03-14 |
2015-11-17 |
샤이어 휴먼 지네틱 테라피즈 인크. |
4''-티오 개질된 뉴클레오티드를 갖는 리보핵산 및 관련 방법
|
|
EP2968760B1
(en)
|
2013-03-15 |
2024-01-03 |
Amgen Inc. |
Drug cassette, autoinjector, and autoinjector system
|
|
CA2904357C
(en)
|
2013-03-15 |
2020-09-22 |
Intrinsic Lifesciences Llc |
Anti-hepcidin antibodies and uses thereof
|
|
BR112015022042B1
(pt)
|
2013-03-15 |
2023-01-10 |
Amgen Inc |
Injetor para injetar um produto terapêutico
|
|
WO2014138921A1
(en)
|
2013-03-15 |
2014-09-18 |
Apotex Inc. |
Enhanced liquid formulation stability of erythropoietin alpha through purification processing
|
|
TWI639449B
(zh)
|
2013-03-15 |
2018-11-01 |
美商安美基公司 |
用於注射器之匣盒
|
|
LT2976117T
(lt)
|
2013-03-22 |
2021-02-25 |
Amgen Inc. |
Purkštuvas ir surinkimo būdas
|
|
US9700485B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9700486B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9707153B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9717649B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9849066B2
(en)
|
2013-04-24 |
2017-12-26 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9603775B2
(en)
|
2013-04-24 |
2017-03-28 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9717648B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9707154B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9707155B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9713572B2
(en)
|
2013-04-24 |
2017-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
US9839579B2
(en)
|
2013-04-24 |
2017-12-12 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
|
AU2014310555B2
(en)
|
2013-08-20 |
2018-01-18 |
Lek Pharmaceuticals D.D. |
Cell culture medium and process for controlling alpha-amidation and/or C-terminal amino acid cleavage of polypeptides
|
|
US20150118187A1
(en)
|
2013-10-24 |
2015-04-30 |
Medgenics Medical Israel Ltd. |
Micro-organs providing sustained delivery of a therapeutic polypeptide and methods of use thereof
|
|
EP3501575B1
(en)
|
2013-10-24 |
2021-12-01 |
Amgen Inc. |
Drug delivery system with temperature-sensitive-control
|
|
JP7086520B2
(ja)
|
2013-10-24 |
2022-06-20 |
アムジエン・インコーポレーテツド |
インジェクター及び組み立ての方法
|
|
US10994112B2
(en)
|
2014-02-05 |
2021-05-04 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
|
SG11201609219QA
(en)
|
2014-05-07 |
2016-12-29 |
Amgen Inc |
Autoinjector with shock reducing elements
|
|
EP3148587B1
(en)
|
2014-05-30 |
2021-02-24 |
Pfizer Inc |
Carbonitrile derivatives as selective androgen receptor modulators
|
|
EP3152694B1
(en)
|
2014-06-03 |
2024-03-06 |
Amgen Inc. |
Systems and methods for remotely processing data collected by a drug delivery device
|
|
NZ730186A
(en)
|
2014-09-22 |
2020-04-24 |
Intrinsic Lifesciences Llc |
Humanized anti-hepcidin antibodies and uses thereof
|
|
CA2957960C
(en)
|
2014-10-14 |
2023-08-22 |
Amgen, Inc. |
Drug injection device with visual and audible indicators
|
|
EP3689394A1
(en)
|
2014-12-19 |
2020-08-05 |
Amgen Inc. |
Drug delivery device with live button or user interface field
|
|
EP3848072A1
(en)
|
2014-12-19 |
2021-07-14 |
Amgen Inc. |
Drug delivery device with proximity sensor
|
|
MX391511B
(es)
|
2015-02-17 |
2025-03-04 |
Amgen Inc |
Dispositivo de administracion de farmacos con sujecion asistida de vacio y/o respuestas.
|
|
US11806509B2
(en)
|
2015-02-27 |
2023-11-07 |
Amgen Inc. |
Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement
|
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
|
WO2017068051A1
(en)
|
2015-10-21 |
2017-04-27 |
Lek Pharmaceuticals D.D. |
Peg-based dendron and process for producing the same
|
|
JP7082568B2
(ja)
|
2015-12-09 |
2022-06-08 |
アムジエン・インコーポレーテツド |
信号伝達キャップ付き自動注射器
|
|
WO2017120178A1
(en)
|
2016-01-06 |
2017-07-13 |
Amgen Inc. |
Auto-injector with signaling electronics
|
|
ES3039908T3
(en)
|
2016-03-15 |
2025-10-27 |
Amgen Inc |
Reducing probability of glass breakage in drug delivery devices
|
|
US11541168B2
(en)
|
2016-04-29 |
2023-01-03 |
Amgen Inc. |
Drug delivery device with messaging label
|
|
WO2017192287A1
(en)
|
2016-05-02 |
2017-11-09 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
|
EP3455142B1
(en)
|
2016-05-13 |
2023-08-09 |
Amgen Inc. |
Vial sleeve assembly
|
|
EP3458988B1
(en)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Data encryption in medical devices with limited computational capability
|
|
WO2017209899A1
(en)
|
2016-06-03 |
2017-12-07 |
Amgen Inc. |
Impact testing apparatuses and methods for drug delivery devices
|
|
WO2018004842A1
(en)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
|
WO2018034784A1
(en)
|
2016-08-17 |
2018-02-22 |
Amgen Inc. |
Drug delivery device with placement detection
|
|
WO2018081234A1
(en)
|
2016-10-25 |
2018-05-03 |
Amgen Inc. |
On-body injector
|
|
US20190358411A1
(en)
|
2017-01-17 |
2019-11-28 |
Amgen Inc. |
Injection devices and related methods of use and assembly
|
|
AU2018221351B2
(en)
|
2017-02-17 |
2023-02-23 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
JP7064501B2
(ja)
|
2017-02-17 |
2022-05-10 |
アムジエン・インコーポレーテツド |
無菌流体流路を備える薬物送達デバイスおよび関連する組立方法
|
|
JP2020508803A
(ja)
|
2017-03-06 |
2020-03-26 |
アムジエン・インコーポレーテツド |
作動防止特徴部を備える薬物送達デバイス
|
|
AU2018230546B2
(en)
|
2017-03-07 |
2024-03-21 |
Amgen Inc. |
Needle insertion by overpressure
|
|
WO2018165499A1
(en)
|
2017-03-09 |
2018-09-13 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
EP3570871B1
(en)
|
2017-03-20 |
2020-11-18 |
H. Hoffnabb-La Roche Ag |
Method for in vitro glycoengineering of an erythropoiesis stimulating protein
|
|
CN114588404B
(zh)
|
2017-03-28 |
2024-07-09 |
美国安进公司 |
柱塞杆和注射器组件系统以及方法
|
|
CA3066399A1
(en)
|
2017-06-08 |
2018-12-13 |
Amgen Inc. |
Torque driven drug delivery device
|
|
CA3061982A1
(en)
|
2017-06-08 |
2018-12-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
|
KR102268647B1
(ko)
|
2017-06-12 |
2021-06-23 |
한국코러스 주식회사 |
안정성이 향상된 에리스로포이에틴 조성물 및 이의 제조방법
|
|
CA3063920A1
(en)
|
2017-06-22 |
2018-12-27 |
Amgen Inc. |
Device activation impact/shock reduction
|
|
WO2018237225A1
(en)
|
2017-06-23 |
2018-12-27 |
Amgen Inc. |
Electronic drug delivery device comprising a cap activated by a switch assembly
|
|
WO2019014014A1
(en)
|
2017-07-14 |
2019-01-17 |
Amgen Inc. |
NEEDLE INSERTION-RETRACTING SYSTEM HAVING DOUBLE TORSION SPRING SYSTEM
|
|
IL271173B2
(en)
|
2017-07-21 |
2024-04-01 |
Amgen Inc |
Gas permeable sealing member for drug container and methods of assembly
|
|
JP7242562B2
(ja)
|
2017-07-25 |
2023-03-20 |
アムジエン・インコーポレーテツド |
容器アクセスシステムを有する薬物送達デバイス及び関連する組立方法
|
|
WO2019022951A1
(en)
|
2017-07-25 |
2019-01-31 |
Amgen Inc. |
DRUG DELIVERY DEVICE WITH GEAR MODULE AND ASSEMBLY METHOD THEREOF
|
|
EP3664863A2
(en)
|
2017-08-09 |
2020-06-17 |
Amgen Inc. |
Hydraulic-pneumatic pressurized chamber drug delivery system
|
|
US11077246B2
(en)
|
2017-08-18 |
2021-08-03 |
Amgen Inc. |
Wearable injector with sterile adhesive patch
|
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
|
WO2019070472A1
(en)
|
2017-10-04 |
2019-04-11 |
Amgen Inc. |
FLOW ADAPTER FOR MEDICATION DELIVERY DEVICE
|
|
EP3691716B1
(en)
|
2017-10-06 |
2023-11-29 |
Amgen Inc. |
Drug delivery device with interlock assembly and related method of assembly
|
|
US11464903B2
(en)
|
2017-10-09 |
2022-10-11 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
|
EP3703778A1
(en)
|
2017-11-03 |
2020-09-09 |
Amgen Inc. |
System and approaches for sterilizing a drug delivery device
|
|
EP3707075A1
(en)
|
2017-11-06 |
2020-09-16 |
Amgen Inc. |
Fill-finish assemblies and related methods
|
|
AU2018358749B2
(en)
|
2017-11-06 |
2024-02-29 |
Amgen Inc. |
Drug delivery device with placement and flow sensing
|
|
JP7247174B2
(ja)
|
2017-11-10 |
2023-03-28 |
アムジエン・インコーポレーテツド |
薬物送達デバイスのプランジャ
|
|
MA50904A
(fr)
|
2017-11-16 |
2020-09-23 |
Amgen Inc |
Mécanisme d'insertion d'aiguille pour dispositif d'administration de médicament
|
|
AU2018368338B2
(en)
|
2017-11-16 |
2024-07-25 |
Amgen Inc. |
Autoinjector with stall and end point detection
|
|
JP7264353B2
(ja)
|
2018-05-24 |
2023-04-25 |
国立大学法人北海道大学 |
新規ベクターおよびその利用
|
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
|
WO2020023336A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
|
WO2020023220A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation
|
|
CA3103682A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Delivery devices for administering drugs
|
|
MA53379A
(fr)
|
2018-07-24 |
2021-06-02 |
Amgen Inc |
Dispositifs d'administration pour l'administration de médicaments
|
|
EP3829692A1
(en)
|
2018-07-31 |
2021-06-09 |
Amgen Inc. |
Fluid path assembly for a drug delivery device
|
|
EP3856284A1
(en)
|
2018-09-24 |
2021-08-04 |
Amgen Inc. |
Interventional dosing systems and methods
|
|
US12042642B2
(en)
|
2018-09-28 |
2024-07-23 |
Amgen Inc. |
Muscle wire escapement activation assembly for a drug delivery device
|
|
MX2021003492A
(es)
|
2018-10-02 |
2021-06-18 |
Amgen Inc |
Sistemas de inyeccion para la administracion de farmacos con transmision de fuerza interna.
|
|
JP7547325B2
(ja)
|
2018-10-05 |
2024-09-09 |
アムジエン・インコーポレーテツド |
投薬量インジケータを有する薬物送達デバイス
|
|
WO2020081480A1
(en)
|
2018-10-15 |
2020-04-23 |
Amgen Inc. |
Platform assembly process for drug delivery device
|
|
SG11202103800RA
(en)
|
2018-10-15 |
2021-05-28 |
Amgen Inc |
Drug delivery device having damping mechanism
|
|
EP3873563A1
(en)
|
2018-11-01 |
2021-09-08 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
TWI831847B
(zh)
|
2018-11-01 |
2024-02-11 |
美商安進公司 |
部分針頭縮回之藥物遞送裝置及其操作方法
|
|
WO2020091956A1
(en)
|
2018-11-01 |
2020-05-07 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
US20220160972A1
(en)
|
2019-04-24 |
2022-05-26 |
Amgen Inc. |
Syringe sterilization verification assemblies and methods
|
|
WO2021041067A2
(en)
|
2019-08-23 |
2021-03-04 |
Amgen Inc. |
Drug delivery device with configurable needle shield engagement components and related methods
|
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
|
WO2022246055A1
(en)
|
2021-05-21 |
2022-11-24 |
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