IL153670A0 - Novel peptides as ns3-serine protease inhibitors of hepatitis c virus - Google Patents

Novel peptides as ns3-serine protease inhibitors of hepatitis c virus

Info

Publication number
IL153670A0
IL153670A0 IL15367001A IL15367001A IL153670A0 IL 153670 A0 IL153670 A0 IL 153670A0 IL 15367001 A IL15367001 A IL 15367001A IL 15367001 A IL15367001 A IL 15367001A IL 153670 A0 IL153670 A0 IL 153670A0
Authority
IL
Israel
Prior art keywords
hepatitis
virus
protease inhibitors
serine protease
novel peptides
Prior art date
Application number
IL15367001A
Other languages
English (en)
Original Assignee
Schering Corp
Corvas Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22822095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL153670(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp, Corvas Int Inc filed Critical Schering Corp
Publication of IL153670A0 publication Critical patent/IL153670A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL15367001A 2000-07-21 2001-07-19 Novel peptides as ns3-serine protease inhibitors of hepatitis c virus IL153670A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22010800P 2000-07-21 2000-07-21
PCT/US2001/022678 WO2002008244A2 (en) 2000-07-21 2001-07-19 Peptides as ns3-serine protease inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
IL153670A0 true IL153670A0 (en) 2003-07-06

Family

ID=22822095

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15367001A IL153670A0 (en) 2000-07-21 2001-07-19 Novel peptides as ns3-serine protease inhibitors of hepatitis c virus
IL153670A IL153670A (en) 2000-07-21 2002-12-25 Peptides as NS3 protease inhibitors - Sirin of the hepatitis C virus

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL153670A IL153670A (en) 2000-07-21 2002-12-25 Peptides as NS3 protease inhibitors - Sirin of the hepatitis C virus

Country Status (31)

Country Link
US (4) US7012066B2 (cg-RX-API-DMAC7.html)
EP (1) EP1385870B1 (cg-RX-API-DMAC7.html)
JP (3) JP4298289B2 (cg-RX-API-DMAC7.html)
KR (2) KR100904788B1 (cg-RX-API-DMAC7.html)
CN (3) CN102206247B (cg-RX-API-DMAC7.html)
AR (2) AR033985A1 (cg-RX-API-DMAC7.html)
AT (1) ATE461207T1 (cg-RX-API-DMAC7.html)
AU (2) AU2001276988B2 (cg-RX-API-DMAC7.html)
BR (1) BR0112540A (cg-RX-API-DMAC7.html)
CA (1) CA2410662C (cg-RX-API-DMAC7.html)
CY (2) CY1112267T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ303213B6 (cg-RX-API-DMAC7.html)
DE (2) DE60141608D1 (cg-RX-API-DMAC7.html)
DK (1) DK1385870T3 (cg-RX-API-DMAC7.html)
EC (1) ECSP034438A (cg-RX-API-DMAC7.html)
ES (1) ES2341534T3 (cg-RX-API-DMAC7.html)
HU (1) HU229997B1 (cg-RX-API-DMAC7.html)
IL (2) IL153670A0 (cg-RX-API-DMAC7.html)
LU (1) LU91910I2 (cg-RX-API-DMAC7.html)
MX (1) MXPA03000627A (cg-RX-API-DMAC7.html)
MY (2) MY139078A (cg-RX-API-DMAC7.html)
NO (2) NO332329B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ523782A (cg-RX-API-DMAC7.html)
PL (1) PL206255B1 (cg-RX-API-DMAC7.html)
PT (1) PT1385870E (cg-RX-API-DMAC7.html)
RU (2) RU2355700C9 (cg-RX-API-DMAC7.html)
SI (1) SI1385870T1 (cg-RX-API-DMAC7.html)
SK (1) SK288064B6 (cg-RX-API-DMAC7.html)
TW (1) TWI324611B (cg-RX-API-DMAC7.html)
WO (1) WO2002008244A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200210312B (cg-RX-API-DMAC7.html)

Families Citing this family (273)

* Cited by examiner, † Cited by third party
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