MX2009011930A - Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c. - Google Patents

Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c.

Info

Publication number
MX2009011930A
MX2009011930A MX2009011930A MX2009011930A MX2009011930A MX 2009011930 A MX2009011930 A MX 2009011930A MX 2009011930 A MX2009011930 A MX 2009011930A MX 2009011930 A MX2009011930 A MX 2009011930A MX 2009011930 A MX2009011930 A MX 2009011930A
Authority
MX
Mexico
Prior art keywords
treatment
present
hcv infection
combination therapy
therapeutic combinations
Prior art date
Application number
MX2009011930A
Other languages
English (en)
Inventor
Chao Lin
Ann Kwong
Nagraj Mani
Yi Zhou
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX2009011930A publication Critical patent/MX2009011930A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a combinaciones terapéuticas que comprenden un inhibidor de proteasa y un inhibidor de polimerasa para el tratamiento de HCV. La presente invención también se refiere a combinaciones terapéuticas que comprenden VX-950 y un inhibidor de polimerasa. También dentro del alcance de la invención estás métodos para usar las combinaciones terapéuticas de la presente invención para tratar infección, de HCV o aliviar uno o más síntomas de la misma en un paciente. La presente invención también proporciona kits que comprenden las combinaciones de la presente invención.
MX2009011930A 2007-05-04 2008-05-05 Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c. MX2009011930A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92758107P 2007-05-04 2007-05-04
US93142507P 2007-05-23 2007-05-23
PCT/US2008/005758 WO2008137126A2 (en) 2007-05-04 2008-05-05 Combination therapy for the treatment of hcv infection

Publications (1)

Publication Number Publication Date
MX2009011930A true MX2009011930A (es) 2009-11-18

Family

ID=39711894

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011930A MX2009011930A (es) 2007-05-04 2008-05-05 Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c.

Country Status (11)

Country Link
US (2) US8258116B2 (es)
EP (2) EP2494991A1 (es)
JP (1) JP2010526143A (es)
CN (2) CN102872461A (es)
AT (1) ATE548044T1 (es)
AU (1) AU2008248116A1 (es)
CA (1) CA2686051A1 (es)
ES (1) ES2381410T3 (es)
MX (1) MX2009011930A (es)
NZ (1) NZ580917A (es)
WO (1) WO2008137126A2 (es)

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SI2709613T2 (sl) * 2011-09-16 2020-12-31 Gilead Pharmasset LLC c/o Gilead Sciences, Inc. Postopki za zdravljenje HCV
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US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
CN106138080A (zh) * 2015-04-03 2016-11-23 南开大学 核苷类化合物在制备治疗丙型肝炎病毒(hcv)感染疾病药物的应用
US11192914B2 (en) 2016-04-28 2021-12-07 Emory University Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto

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