ATE548044T1 - Kombinationstherapie zur behandlung von hiv- infektionen - Google Patents

Kombinationstherapie zur behandlung von hiv- infektionen

Info

Publication number
ATE548044T1
ATE548044T1 AT08767561T AT08767561T ATE548044T1 AT E548044 T1 ATE548044 T1 AT E548044T1 AT 08767561 T AT08767561 T AT 08767561T AT 08767561 T AT08767561 T AT 08767561T AT E548044 T1 ATE548044 T1 AT E548044T1
Authority
AT
Austria
Prior art keywords
treatment
present
combination therapy
hiv infections
therapeutic combinations
Prior art date
Application number
AT08767561T
Other languages
English (en)
Inventor
Ann Kwong
Nagraj Mani
Yi Zhou
Chao Lin
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of ATE548044T1 publication Critical patent/ATE548044T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT08767561T 2007-05-04 2008-05-05 Kombinationstherapie zur behandlung von hiv- infektionen ATE548044T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92758107P 2007-05-04 2007-05-04
US93142507P 2007-05-23 2007-05-23
PCT/US2008/005758 WO2008137126A2 (en) 2007-05-04 2008-05-05 Combination therapy for the treatment of hcv infection

Publications (1)

Publication Number Publication Date
ATE548044T1 true ATE548044T1 (de) 2012-03-15

Family

ID=39711894

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08767561T ATE548044T1 (de) 2007-05-04 2008-05-05 Kombinationstherapie zur behandlung von hiv- infektionen

Country Status (11)

Country Link
US (2) US8258116B2 (de)
EP (2) EP2142215B1 (de)
JP (1) JP2010526143A (de)
CN (2) CN101815533A (de)
AT (1) ATE548044T1 (de)
AU (1) AU2008248116A1 (de)
CA (1) CA2686051A1 (de)
ES (1) ES2381410T3 (de)
MX (1) MX2009011930A (de)
NZ (1) NZ580917A (de)
WO (1) WO2008137126A2 (de)

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EP2709613B2 (de) * 2011-09-16 2020-08-12 Gilead Pharmasset LLC Verfahren zur behandlung von hcv
PT107924A (pt) 2011-10-21 2014-12-03 Abbvie Inc Tratamento de combinação de daa (eg. com abt-072 ou abt-333) para utilização no tratamento de hcv
WO2013059630A1 (en) 2011-10-21 2013-04-25 Abbvie Inc. Methods for treating hcv comprising at least two direct acting antiviral agent, ribavirin but not interferon.
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
CN106138080A (zh) * 2015-04-03 2016-11-23 南开大学 核苷类化合物在制备治疗丙型肝炎病毒(hcv)感染疾病药物的应用
WO2017189978A1 (en) 2016-04-28 2017-11-02 Emory University Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto

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US8258116B2 (en) 2012-09-04
US20100172866A1 (en) 2010-07-08
WO2008137126A2 (en) 2008-11-13
CN101815533A (zh) 2010-08-25
MX2009011930A (es) 2009-11-18
EP2142215B1 (de) 2012-03-07
WO2008137126A3 (en) 2009-04-09
CN102872461A (zh) 2013-01-16
EP2494991A1 (de) 2012-09-05
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ES2381410T3 (es) 2012-05-28
JP2010526143A (ja) 2010-07-29

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