UY32826A - Compuestos heterocíclicos - Google Patents

Compuestos heterocíclicos

Info

Publication number
UY32826A
UY32826A UY0001032826A UY32826A UY32826A UY 32826 A UY32826 A UY 32826A UY 0001032826 A UY0001032826 A UY 0001032826A UY 32826 A UY32826 A UY 32826A UY 32826 A UY32826 A UY 32826A
Authority
UY
Uruguay
Prior art keywords
heterocyclic compounds
present
compound
iap
symbol
Prior art date
Application number
UY0001032826A
Other languages
English (en)
Inventor
Oguro Yuya
Ishikawa Tomoyasu
Hashimoto Kentaro
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of UY32826A publication Critical patent/UY32826A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención provee un compuesto representado por la fórmula en donde cada símbolo es como se define en la memoria descriptiva o una de sus sales. El compuesto de la presente invención muestra una fuerte actividad antagonista de IAP.
UY0001032826A 2009-08-04 2010-08-03 Compuestos heterocíclicos UY32826A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009181933 2009-08-04
JP2010003403 2010-01-08

Publications (1)

Publication Number Publication Date
UY32826A true UY32826A (es) 2011-02-28

Family

ID=42984006

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032826A UY32826A (es) 2009-08-04 2010-08-03 Compuestos heterocíclicos

Country Status (5)

Country Link
US (1) US20110034469A1 (es)
AR (1) AR077688A1 (es)
TW (1) TW201109335A (es)
UY (1) UY32826A (es)
WO (1) WO2011016576A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY33794A (es) 2010-12-13 2012-07-31 Novartis Ag Inhibidores diméricos de las iap

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125534A (en) 1977-02-25 1978-11-14 Allied Chemical Corporation Carbazolyl diacetylenic compounds
US4539411A (en) 1982-02-05 1985-09-03 Hoffmann-La Roche Inc. Rhodium complexes of chiral phosphines
US4400511A (en) 1982-05-07 1983-08-23 American Home Products Corporation 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids
PT82468B (en) 1985-04-30 1988-03-23 Lilly Co Eli Process for preparing 7-substituted bycyclic pyrazolidinones
GB8912303D0 (en) 1989-05-27 1989-07-12 Pfizer Ltd Therapeutic agents
US5292766A (en) 1992-03-25 1994-03-08 Eli Lilly And Company Method for improving primary memory and/or learning
US6511974B1 (en) 1997-07-30 2003-01-28 Wyeth Tricyclic vasopressin agonists
US5932745A (en) 1997-07-30 1999-08-03 American Home Products Corporation Process for converting propargylic amine-N-oxides to enaminones
US6436904B1 (en) 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
DE60044395D1 (de) 1999-03-26 2010-06-24 Euro Celtique Sa Arylsubstituierte pyrazole, imidazole, oxazole, thiazole und pyrrole, sowie deren verwendung
EP1178982B1 (en) 1999-05-21 2004-06-30 Abbott Laboratories Heterocyclic substituted aminoazacycles useful as central nervous system agents
US6756378B2 (en) 1999-06-30 2004-06-29 Pharmacopeia Drug Discovery, Inc. VLA-4 inhibitor compounds
AU6643800A (en) 1999-08-16 2001-03-13 University Of Southern California Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes
PL206255B1 (pl) 2000-07-21 2010-07-30 Dendreon Corporationdendreon Corporation Inhibitor proteazy wirusa zapalenia wątroby C, zawierająca go kompozycja farmaceutyczna i zastosowanie inhibitora do wytwarzania leku do leczenia chorób związanych z HCV oraz zastosowanie do wytwarzania kompozycji do stosowania w kombinowanej terapii
CA2438272A1 (en) 2001-03-02 2002-10-10 John Macor Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
US6906206B2 (en) 2001-04-30 2005-06-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US7196111B2 (en) 2002-06-04 2007-03-27 Schering Corporation Pyrazolo[1,5a]pyrimidine compounds as antiviral agents
JP4541882B2 (ja) 2002-07-02 2010-09-08 ノバルティス アーゲー Ｓｍａｃタンパク質のアポトーシスタンパク質阻害物質（ｉａｐ）との結合に対するペプチド阻害剤
KR20050044902A (ko) 2002-08-12 2005-05-13 다케다 야쿠힌 고교 가부시키가이샤 축합 벤젠 유도체 및 용도
TW200504033A (en) 2002-10-23 2005-02-01 Procter & Gamble Melanocortin receptor ligands
MXPA05008295A (es) 2003-02-05 2005-09-20 Bayer Cropscience Gmbh Amino-1,3,5-triazinas sustituidas en n con radicales biciclicos quirales, procedimiento para su preparacion, composiciones de las mismas, y su uso como herbicidas y reguladores del crecimiento de las plantas.
CA2526770A1 (en) 2003-06-06 2004-12-23 Merck & Co., Inc. Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1661898A4 (en) * 2003-08-29 2009-04-15 Takeda Pharmaceutical BICYCLIC PIPERAZINE COMPOUND AND USE THEREOF
PL1682537T3 (pl) 2003-11-05 2012-09-28 Sarcode Bioscience Inc Modulatory adhezji komórkowej
US7989634B2 (en) 2003-11-12 2011-08-02 Lg Life Sciences Ltd. Melanocortin receptor agonists
WO2005047253A1 (en) 2003-11-12 2005-05-26 Lg Life Sciences Ltd. Melanocortin receptor agonists
TW200526588A (en) 2003-11-17 2005-08-16 Smithkline Beecham Corp Chemical compounds
CA2548918C (en) 2003-12-11 2013-05-21 Mitsubishi Pharma Corporation Alpha-amino acid derivatives and use thereof as medicines
US7355051B2 (en) 2003-12-18 2008-04-08 Tibotec Pharmaceuticals Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
WO2005079574A1 (en) * 2004-01-21 2005-09-01 Palatin Technologies, Inc. Bicyclic melanocorin-specific compounds
AU2005228950B2 (en) 2004-03-23 2012-02-02 Genentech, Inc. Azabicyclo-octane inhibitors of IAP
NZ549925A (en) * 2004-04-07 2010-08-27 Novartis Ag Inhibitors of IAP
WO2005100334A1 (en) 2004-04-14 2005-10-27 Pfizer Products Inc. Dipeptidyl peptidase-iv inhibitors
US20100190688A1 (en) 2004-07-12 2010-07-29 Bin Chao Tetrapeptide analogs
WO2006038119A1 (en) 2004-10-08 2006-04-13 Warner-Lambert Company Llc Stereoselective synthesis of n-protected alkoxy prolines
JP2008520693A (ja) 2004-11-18 2008-06-19 ジ インスチチュート フォー ファーマシューティカル ディスカバリー、エルエルシー プロテインチロシンホスファターゼ阻害剤としての置換アミノ酸
DE602005022936D1 (de) 2004-12-20 2010-09-23 Genentech Inc Pyrrolidine als inhibitoren von iap
DE102005017116A1 (de) * 2005-04-13 2006-10-26 Novartis Ag Hemmstoffe für Inhibitoren von Apoptose Proteinen (IAP)
EP1888619B1 (en) 2005-05-25 2013-04-17 2cureX ApS Compounds modifying apoptosis
WO2006134341A1 (en) 2005-06-13 2006-12-21 Merck Sharp & Dohme Limited Therapeutic agents
MX2008001386A (es) 2005-08-10 2008-04-07 Takeda Pharmaceutical Agente terapeutico para diabetes.
DK1928886T3 (da) 2005-09-09 2011-07-11 Glaxosmithkline Llc Pyridin-derivater og deres anvendelse i behandlingen af psykotiske lidelser
CN101374829A (zh) 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂
CA2638787A1 (en) 2006-02-16 2007-08-23 Takeda Pharmaceutical Company Limited Cyclic amine compound and use thereof for the prophylaxis or treatment of hypertension
WO2007107827A1 (en) 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
CA2646186A1 (en) 2006-03-21 2007-11-29 Joyant Pharmaceuticals, Inc. Small molecule apoptosis promoters
PE20110217A1 (es) 2006-08-02 2011-04-01 Novartis Ag DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
DK2091536T3 (da) 2006-09-26 2013-10-28 Crestone Inc Enantiomere forbindelser med antibakteriel aktivitet
MX2009003834A (es) 2006-10-12 2009-04-22 Novartis Ag Derivados de pirrolidina como inhibidores de iap.
JP2010513561A (ja) 2006-12-19 2010-04-30 ジェネンテック， インコーポレイテッド Ｉａｐのイミダゾピリジンインヒビター
EP2120938A4 (en) 2006-12-20 2010-12-08 Merck Sharp & Dohme IMIDAZOPYRIDINE ANALOGUE AS CB2 RECEPTOR MODULATORS FOR THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES
GB0625648D0 (en) 2006-12-21 2007-01-31 Glaxo Group Ltd Compounds
US20090123423A1 (en) 2007-04-26 2009-05-14 Yonghua Gai Hydroxyamic analogs as hepatitis c virus serine protease inhibitor
WO2008144925A1 (en) 2007-05-30 2008-12-04 Aegera Therapeutics Inc. Iap bir domain binding compounds
KR20100038417A (ko) 2007-06-29 2010-04-14 길리애드 사이언시즈, 인코포레이티드 항바이러스 화합물
WO2009048474A1 (en) 2007-10-12 2009-04-16 Pharmacopeia, Inc. 2,7,9-substituted purinone derivatives for immunosuppression
AR070413A1 (es) 2008-02-04 2010-04-07 Idenix Pharmaceuticals Inc Inhibidores macrociclicos de proteasa de serina

Also Published As

Publication number Publication date
WO2011016576A1 (en) 2011-02-10
US20110034469A1 (en) 2011-02-10
AR077688A1 (es) 2011-09-14
TW201109335A (en) 2011-03-16

Similar Documents

Publication Publication Date Title
DOP2014000064A (es) Compuestos 1-arilcarbonil-4-oxi-piperidina útiles para el tratamiento de enfermedades neurodegenerativas
UY36199A (es) Compuesto heterocíclico
CR20110635A (es) Quinazolinas sustituidas como fungicidas
EA201290800A1 (ru) Гетероциклическое соединение
CR20150509A (es) Derivados de naftiridina utiles como antagonistas de la alfa-v-beta-6 integrina
CR20140132A (es) Derivados de pirrolopirimidina y purina
EA201071032A1 (ru) Гетероциклическое соединение
CR20140468A (es) Inhibidores de diacilglicerol aciltransferasa 2
DOP2011000165A (es) Compuesto heterociclico y uso del mismo
CR20130419A (es) Derivados heterocíclicos de amina
GT201400290A (es) Carboxamidas heterociclicas fungicidas
CR20130369A (es) Novedosos derivados heterocíclicos
PE20150666A1 (es) Inhibidores de serina/treonina cinasa
ECSP13012478A (es) Compuesto heterocíclico y su uso
CR20140084A (es) Derivados de 2-amino-4-(piridin-2-il)-5,6-dihidro-4h-1,3-oxazina y su uso como inhibidores de bace-1 y/o bace-2
CR20120064A (es) Heterociclos microbicidas
CR20120053A (es) Compuestos y metodos inhibidores de jak de pirazolopirimidina
CR20150061A (es) Compuesto de pirazolopirimidinas
BRPI0809974A2 (pt) Compostos de pirimidina hidrazida como inibidores de pgds
ATE539070T1 (de) Heterozyklische antivirale verbindungen
CR20140306A (es) Fluormetil -5,6-dihidro-4h-[1,3] oxazinas
CR20140495A (es) 5-amino[1,4]thiazines como inhibidores de bace1
CR20160073A (es) Compuestos plaguicidas
CR20150084A (es) 2-oxo-2,3-dihidro-indoles
UY34251A (es) derivados de isoxazolina como compuestos insecticidas.

Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20130308