ATE539070T1 - Heterozyklische antivirale verbindungen - Google Patents
Heterozyklische antivirale verbindungenInfo
- Publication number
- ATE539070T1 ATE539070T1 AT09710988T AT09710988T ATE539070T1 AT E539070 T1 ATE539070 T1 AT E539070T1 AT 09710988 T AT09710988 T AT 09710988T AT 09710988 T AT09710988 T AT 09710988T AT E539070 T1 ATE539070 T1 AT E539070T1
- Authority
- AT
- Austria
- Prior art keywords
- antiviral compounds
- heterocyclic antiviral
- heterocyclic
- compounds
- antiviral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2862908P | 2008-02-14 | 2008-02-14 | |
| US13860308P | 2008-12-18 | 2008-12-18 | |
| PCT/EP2009/051306 WO2009101022A1 (en) | 2008-02-14 | 2009-02-05 | Heterocyclic antiviral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE539070T1 true ATE539070T1 (de) | 2012-01-15 |
Family
ID=40521706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09710988T ATE539070T1 (de) | 2008-02-14 | 2009-02-05 | Heterozyklische antivirale verbindungen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8071797B2 (de) |
| EP (1) | EP2245023B1 (de) |
| JP (1) | JP2011512341A (de) |
| KR (1) | KR20100117073A (de) |
| CN (1) | CN101910145A (de) |
| AR (1) | AR070361A1 (de) |
| AT (1) | ATE539070T1 (de) |
| AU (1) | AU2009214194B2 (de) |
| BR (1) | BRPI0907885A2 (de) |
| CA (1) | CA2714254A1 (de) |
| CL (1) | CL2009000305A1 (de) |
| ES (1) | ES2377280T3 (de) |
| IL (1) | IL204736A0 (de) |
| MX (1) | MX2010004623A (de) |
| PE (1) | PE20091458A1 (de) |
| RU (1) | RU2010137635A (de) |
| TW (1) | TW200936573A (de) |
| WO (1) | WO2009101022A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8048887B2 (en) | 2008-09-11 | 2011-11-01 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US8293909B2 (en) | 2008-09-11 | 2012-10-23 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US8198449B2 (en) | 2008-09-11 | 2012-06-12 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US7994171B2 (en) | 2008-09-11 | 2011-08-09 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| AU2010299928A1 (en) * | 2009-09-24 | 2012-02-02 | F. Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
| US8324212B2 (en) | 2010-02-25 | 2012-12-04 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US8354410B2 (en) | 2010-03-11 | 2013-01-15 | Bristol-Meyers Squibb Company | Compounds for the treatment of hepatitis C |
| CN102906080A (zh) * | 2010-03-11 | 2013-01-30 | 百时美施贵宝公司 | 治疗丙型肝炎的化合物 |
| AR082453A1 (es) * | 2010-04-21 | 2012-12-12 | Novartis Ag | Compuestos de furopiridina, composiciones farmaceuticas que los contienen y usos de los mismos |
| US8445497B2 (en) | 2010-06-30 | 2013-05-21 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| AU2011320696B2 (en) | 2010-10-26 | 2016-07-21 | Presidio Pharmaceuticals, Inc. | Inhibitors of Hepatitis C Virus |
| US8507683B2 (en) | 2010-12-09 | 2013-08-13 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| CN106986862A (zh) | 2010-12-22 | 2017-07-28 | Abbvie 公司 | 丙型肝炎抑制剂及其用途 |
| PE20141391A1 (es) * | 2011-08-17 | 2014-10-29 | Glaxosmithkline Llc | Combinacion que comprende un compuesto con actividad antiviral y un agente terapeutico |
| MX354676B (es) * | 2011-08-19 | 2018-03-15 | Glaxo Group Ltd | Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv). |
| WO2013033900A1 (en) | 2011-09-08 | 2013-03-14 | Merck Sharp & Dohme Corp. | Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases |
| WO2013033901A1 (en) | 2011-09-08 | 2013-03-14 | Merck Sharp & Dohme Corp. | Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases |
| WO2013033899A1 (en) | 2011-09-08 | 2013-03-14 | Merck Sharp & Dohme Corp. | Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases |
| US9303020B2 (en) | 2012-02-08 | 2016-04-05 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US9096580B2 (en) | 2012-03-27 | 2015-08-04 | Bristol-Myers Squibb Company | Benzofuran derivatives for the treatment of hepatitis C |
| WO2014110066A1 (en) | 2013-01-10 | 2014-07-17 | Bristol-Myers Squibb Company | Macrocyclic benzofuran and azabenzofuran compounds for the treatment of hepatitis c |
| US8962651B2 (en) | 2013-03-13 | 2015-02-24 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US9738653B2 (en) | 2013-03-14 | 2017-08-22 | Bristol-Myers Squibb Company | Fused furans for the treatment of hepatitis C |
| ES2688554T3 (es) | 2014-03-21 | 2018-11-05 | Bristol-Myers Squibb Company | Compuestos de azabenzofurano que contienen ciano para el tratamiento de la hepatitis C |
| WO2015143256A1 (en) * | 2014-03-21 | 2015-09-24 | Bristol-Myers Squibb Company | Cyanoamino (aza)benzofuran compounds for the treatment of hepatitis c |
| WO2015143257A1 (en) | 2014-03-21 | 2015-09-24 | Bristol-Myers Squibb Company | 6h-furo[2,3-e]indole compounds for the treatment of hepatitis c |
| EP3145932B1 (de) | 2014-05-21 | 2018-08-15 | Bristol-Myers Squibb Company | 2-(aryl- oder heteroaryl-)phenyl-(aza)benzofuran-verbindungen zur behandlung von hepatitis c |
| WO2015191653A1 (en) | 2014-06-11 | 2015-12-17 | Bristol-Myers Squibb Company | Substituted 2-phenyl (aza)benzofuran compounds for the treatment of hepatitis c |
| WO2016022513A1 (en) | 2014-08-05 | 2016-02-11 | Bristol-Myers Squibb Company | Furopyridine compounds for the treatment of hepatitis c |
| WO2016045587A1 (zh) | 2014-09-26 | 2016-03-31 | 常州寅盛药业有限公司 | 作为ns4b抑制剂的苯并呋喃类似物 |
| EP3201202A1 (de) | 2014-10-02 | 2017-08-09 | Bristol-Myers Squibb Company | Makrocyclische benzofuranverbindungen zur behandlung von hepatitis c |
| US10087167B2 (en) | 2015-02-19 | 2018-10-02 | Bristol-Myers Squibb Company | Benzofurans substituted with secondary benzamide as HCV inhibitors |
| US10131645B2 (en) | 2015-02-19 | 2018-11-20 | Bristol-Myers Squibb Company | Benzofurans substituted with primary benzamide as HCV inhibitors |
| WO2016133961A1 (en) | 2015-02-19 | 2016-08-25 | Bristol-Myers Squibb Company | Benzofurans substituted with bicyclic secondary benzamide as hcv inhibitors |
| US10570108B2 (en) | 2015-02-19 | 2020-02-25 | Bristol-Myers Squibb Company | Substituted benzofuran compounds for the treatment of hepatitis C |
| US10125111B2 (en) | 2015-02-19 | 2018-11-13 | Bristol-Myers Squibb Company | Benzofuran compounds for the treatment of hepatitis C |
| TWI731854B (zh) | 2015-03-23 | 2021-07-01 | 美商共結晶製藥公司 | Ｃ型肝炎病毒聚合酶之抑制劑 |
| CN105732602B (zh) * | 2015-09-23 | 2017-04-19 | 常州寅盛药业有限公司 | 作为ns4b抑制剂的苯并呋喃类似物 |
| PL3378859T3 (pl) * | 2015-11-19 | 2020-04-30 | Jiangsu Hengrui Medicine Co., Ltd. | Pochodna benzofuranu, sposób jej wytwarzania i jej zastosowanie w medycynie |
| RU2771234C2 (ru) | 2015-11-24 | 2022-04-28 | Л'Ореаль | Композиции для обработки волос |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA79834C2 (en) * | 2002-11-01 | 2007-07-25 | Viropharma Inc | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
| US20070224167A1 (en) * | 2006-02-09 | 2007-09-27 | Schering Corporation | Novel HCV inhibitor combinations and methods |
| US20090047246A1 (en) * | 2007-02-12 | 2009-02-19 | Intermune, Inc. | Novel inhibitors of hepatitis c virus replication |
-
2009
- 2009-02-05 AU AU2009214194A patent/AU2009214194B2/en not_active Ceased
- 2009-02-05 CN CN2009801015270A patent/CN101910145A/zh active Pending
- 2009-02-05 JP JP2010546292A patent/JP2011512341A/ja active Pending
- 2009-02-05 MX MX2010004623A patent/MX2010004623A/es active IP Right Grant
- 2009-02-05 CA CA2714254A patent/CA2714254A1/en not_active Abandoned
- 2009-02-05 RU RU2010137635/04A patent/RU2010137635A/ru not_active Application Discontinuation
- 2009-02-05 EP EP09710988A patent/EP2245023B1/de not_active Not-in-force
- 2009-02-05 BR BRPI0907885-1A patent/BRPI0907885A2/pt not_active IP Right Cessation
- 2009-02-05 AT AT09710988T patent/ATE539070T1/de active
- 2009-02-05 ES ES09710988T patent/ES2377280T3/es active Active
- 2009-02-05 KR KR1020107017891A patent/KR20100117073A/ko not_active Application Discontinuation
- 2009-02-05 WO PCT/EP2009/051306 patent/WO2009101022A1/en active Application Filing
- 2009-02-11 CL CL2009000305A patent/CL2009000305A1/es unknown
- 2009-02-11 TW TW098104353A patent/TW200936573A/zh unknown
- 2009-02-12 US US12/378,346 patent/US8071797B2/en not_active Expired - Fee Related
- 2009-02-12 AR ARP090100481A patent/AR070361A1/es not_active Application Discontinuation
- 2009-02-13 PE PE2009000213A patent/PE20091458A1/es not_active Application Discontinuation
-
2010
- 2010-03-25 IL IL204736A patent/IL204736A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009214194A1 (en) | 2009-08-20 |
| AU2009214194B2 (en) | 2012-05-17 |
| AR070361A1 (es) | 2010-03-31 |
| IL204736A0 (en) | 2010-11-30 |
| US8071797B2 (en) | 2011-12-06 |
| BRPI0907885A2 (pt) | 2015-07-21 |
| RU2010137635A (ru) | 2012-03-20 |
| JP2011512341A (ja) | 2011-04-21 |
| CN101910145A (zh) | 2010-12-08 |
| TW200936573A (en) | 2009-09-01 |
| ES2377280T3 (es) | 2012-03-26 |
| KR20100117073A (ko) | 2010-11-02 |
| MX2010004623A (es) | 2010-06-07 |
| EP2245023A1 (de) | 2010-11-03 |
| WO2009101022A1 (en) | 2009-08-20 |
| CL2009000305A1 (es) | 2010-02-19 |
| US20090208449A1 (en) | 2009-08-20 |
| CA2714254A1 (en) | 2009-08-20 |
| EP2245023B1 (de) | 2011-12-28 |
| PE20091458A1 (es) | 2009-09-24 |
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