FI941474A0 - Seos nukleiinihappo-kompleksien viemiseksi korkeampiin eukaryoottisiin soluihin - Google Patents

Seos nukleiinihappo-kompleksien viemiseksi korkeampiin eukaryoottisiin soluihin

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Publication number
FI941474A0
FI941474A0 FI941474A FI941474A FI941474A0 FI 941474 A0 FI941474 A0 FI 941474A0 FI 941474 A FI941474 A FI 941474A FI 941474 A FI941474 A FI 941474A FI 941474 A0 FI941474 A0 FI 941474A0
Authority
FI
Finland
Prior art keywords
nucleic acid
eukaryotic cells
higher eukaryotic
mixture
acid complexes
Prior art date
Application number
FI941474A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941474A (fi
Inventor
David Curiel
Ernst Wagner
Matt Cotten
Kurt Zatloukal
Christian Plank
Max L Birnstiel
Bernd Oberhauser
Walter G M Schmidt
Original Assignee
Boehringer Ingelheim Int
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Univ North Carolina filed Critical Boehringer Ingelheim Int
Publication of FI941474A0 publication Critical patent/FI941474A0/fi
Publication of FI941474A publication Critical patent/FI941474A/fi

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10011—Adenoviridae
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2770/32011—Picornaviridae
    • C12N2770/32711—Rhinovirus
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    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32711—Rhinovirus
    • C12N2770/32761—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI941474A 1991-09-30 1994-03-30 Seos nukleiinihappo-kompleksien viemiseksi korkeampiin eukaryoottisiin soluihin FI941474A (fi)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US76803991A 1991-09-30 1991-09-30
US76778891A 1991-09-30 1991-09-30
US82710292A 1992-01-30 1992-01-30
US82710392A 1992-01-30 1992-01-30
US86475992A 1992-04-07 1992-04-07
US93778892A 1992-09-02 1992-09-02
PCT/EP1992/002234 WO1993007283A1 (de) 1991-09-30 1992-09-28 Zusammensetzung für das einbringen von nukleinsäure-komplexen in höhere eukaryotische zellen

Publications (2)

Publication Number Publication Date
FI941474A0 true FI941474A0 (fi) 1994-03-30
FI941474A FI941474A (fi) 1994-03-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
FI941474A FI941474A (fi) 1991-09-30 1994-03-30 Seos nukleiinihappo-kompleksien viemiseksi korkeampiin eukaryoottisiin soluihin

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US (4) US5547932A (da)
EP (2) EP0545016A1 (da)
JP (1) JPH10506001A (da)
CN (1) CN1059705C (da)
AT (1) ATE215990T1 (da)
AU (1) AU671084B2 (da)
BG (1) BG62740B1 (da)
BR (1) BR9206559A (da)
CA (1) CA2118816C (da)
CZ (1) CZ293141B6 (da)
DE (1) DE59209951D1 (da)
DK (1) DK0607206T3 (da)
EE (1) EE03195B1 (da)
ES (1) ES2173083T3 (da)
FI (1) FI941474A (da)
HK (1) HK1013104A1 (da)
HU (2) HU218846B (da)
IL (1) IL103171A (da)
MX (1) MX9205543A (da)
NO (1) NO316744B1 (da)
NZ (1) NZ244306A (da)
PL (1) PL180304B1 (da)
PT (1) PT607206E (da)
RO (1) RO117861B1 (da)
SG (1) SG44680A1 (da)
SI (1) SI9200236B (da)
SK (1) SK281682B6 (da)
WO (1) WO1993007283A1 (da)

Families Citing this family (419)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354844A (en) * 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
US5981273A (en) * 1991-09-30 1999-11-09 Boehringer Ingelheim Int'l. Gmbh Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
JPH07505283A (ja) * 1992-03-20 1995-06-15 ベイラー・カレッジ・オブ・メディシン Ｄｎａトランスポーター系および使用方法
CA2133323C (en) * 1992-04-03 2010-10-26 Francis C. Szoka, Jr. Self-assembling polynucleotide delivery system
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