PT607206E - Composicao para a introducao de complexos de acidos nucleicos em celulas eucarioticas superiores - Google Patents

Composicao para a introducao de complexos de acidos nucleicos em celulas eucarioticas superiores

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Publication number
PT607206E
PT607206E PT92920580T PT92920580T PT607206E PT 607206 E PT607206 E PT 607206E PT 92920580 T PT92920580 T PT 92920580T PT 92920580 T PT92920580 T PT 92920580T PT 607206 E PT607206 E PT 607206E
Authority
PT
Portugal
Prior art keywords
cells
composition
nucleic acid
eucary
introduction
Prior art date
Application number
PT92920580T
Other languages
English (en)
Inventor
David Curiel
Matt Cotten
Ernst Wagner
Kurt Zatloukal
Max L Birnstiel
Bernd Oberhauser
Walter G M Schmidt
Christian Plank
Original Assignee
Genentech Inc
Univ North Carolina
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Univ North Carolina, Boehringer Ingelheim Int filed Critical Genentech Inc
Publication of PT607206E publication Critical patent/PT607206E/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT92920580T 1991-09-30 1992-09-28 Composicao para a introducao de complexos de acidos nucleicos em celulas eucarioticas superiores PT607206E (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US76803991A 1991-09-30 1991-09-30
US76778891A 1991-09-30 1991-09-30
US82710392A 1992-01-30 1992-01-30
US82710292A 1992-01-30 1992-01-30
US86475992A 1992-04-07 1992-04-07
US93778892A 1992-09-02 1992-09-02

Publications (1)

Publication Number Publication Date
PT607206E true PT607206E (pt) 2002-07-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
PT92920580T PT607206E (pt) 1991-09-30 1992-09-28 Composicao para a introducao de complexos de acidos nucleicos em celulas eucarioticas superiores

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US (4) US5547932A (pt)
EP (2) EP0545016A1 (pt)
JP (1) JPH10506001A (pt)
CN (1) CN1059705C (pt)
AT (1) ATE215990T1 (pt)
AU (1) AU671084B2 (pt)
BG (1) BG62740B1 (pt)
BR (1) BR9206559A (pt)
CA (1) CA2118816C (pt)
CZ (1) CZ293141B6 (pt)
DE (1) DE59209951D1 (pt)
DK (1) DK0607206T3 (pt)
EE (1) EE03195B1 (pt)
ES (1) ES2173083T3 (pt)
FI (1) FI941474A0 (pt)
HK (1) HK1013104A1 (pt)
HU (2) HU218846B (pt)
IL (1) IL103171A (pt)
MX (1) MX9205543A (pt)
NO (1) NO316744B1 (pt)
NZ (1) NZ244306A (pt)
PL (1) PL180304B1 (pt)
PT (1) PT607206E (pt)
RO (1) RO117861B1 (pt)
SG (1) SG44680A1 (pt)
SI (1) SI9200236B (pt)
SK (1) SK281682B6 (pt)
WO (1) WO1993007283A1 (pt)

Families Citing this family (419)

* Cited by examiner, † Cited by third party
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US5354844A (en) * 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
US5981273A (en) * 1991-09-30 1999-11-09 Boehringer Ingelheim Int'l. Gmbh Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
AU671450B2 (en) * 1992-03-20 1996-08-29 Baylor College Of Medicine A DNA transporter system and method of use
WO1993019768A1 (en) * 1992-04-03 1993-10-14 The Regents Of The University Of California Self-assembling polynucleotide delivery system
WO1994006923A1 (en) * 1992-09-24 1994-03-31 The University Of Connecticut Modification of a virus to redirect infectivity and enhance targeted delivery of polynucleotides to cells
CN1119459A (zh) * 1993-03-19 1996-03-27 柏伦格-英格尔海姆国际股份公司 肿瘤疫苗的制备方法
DE4311651A1 (de) * 1993-04-08 1994-10-13 Boehringer Ingelheim Int Virus für den Transport von Fremd-DNA in höhere eukaryotische Zellen
US5578475A (en) * 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
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HU211925A9 (en) 1996-01-29
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