FI3526323T3 - Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja - Google Patents

Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja Download PDF

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FI3526323T3
FI3526323T3 FIEP17804977.1T FI17804977T FI3526323T3 FI 3526323 T3 FI3526323 T3 FI 3526323T3 FI 17804977 T FI17804977 T FI 17804977T FI 3526323 T3 FI3526323 T3 FI 3526323T3
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meganuclease
engineered
engineered meganuclease
pharmaceutical composition
nucleic acid
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FIEP17804977.1T
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Finnish (fi)
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Derek Jantz
James Smith
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Prec Biosciences Inc
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FIEP17804977.1T 2016-10-14 2017-10-13 Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja FI3526323T3 (fi)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408356P 2016-10-14 2016-10-14
US201762452506P 2017-01-31 2017-01-31
US201762527196P 2017-06-30 2017-06-30
US201762527159P 2017-06-30 2017-06-30
PCT/US2017/056638 WO2018071849A2 (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

Publications (1)

Publication Number Publication Date
FI3526323T3 true FI3526323T3 (fi) 2023-06-06

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FIEP17804977.1T FI3526323T3 (fi) 2016-10-14 2017-10-13 Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja

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US (6) US10662416B2 (enExample)
EP (2) EP4234691A3 (enExample)
JP (5) JP6811857B2 (enExample)
KR (4) KR20240123417A (enExample)
CN (2) CN117402852A (enExample)
AU (2) AU2017342536A1 (enExample)
BR (1) BR112019007450A2 (enExample)
CA (1) CA3040143A1 (enExample)
CL (1) CL2019000993A1 (enExample)
CO (1) CO2019003675A2 (enExample)
CR (1) CR20190181A (enExample)
DK (1) DK3526323T5 (enExample)
DO (1) DOP2019000097A (enExample)
FI (1) FI3526323T3 (enExample)
IL (3) IL265921B2 (enExample)
MA (1) MA46535A (enExample)
MX (2) MX2019004349A (enExample)
PE (1) PE20191353A1 (enExample)
PH (1) PH12019500788A1 (enExample)
SG (2) SG10201914029RA (enExample)
WO (1) WO2018071849A2 (enExample)

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