DK3526323T5 - Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet - Google Patents

Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet Download PDF

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DK3526323T5
DK3526323T5 DK17804977.1T DK17804977T DK3526323T5 DK 3526323 T5 DK3526323 T5 DK 3526323T5 DK 17804977 T DK17804977 T DK 17804977T DK 3526323 T5 DK3526323 T5 DK 3526323T5
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hepatitis
recognition sequence
virus genome
modified meganucleases
meganucleases specific
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DK17804977.1T
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Danish (da)
English (en)
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DK3526323T3 (da
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Derek Jantz
James Jefferson Smith
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Prec Biosciences Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12N2730/00—Reverse transcribing DNA viruses
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    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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DK17804977.1T 2016-10-14 2017-10-13 Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet DK3526323T5 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408356P 2016-10-14 2016-10-14
US201762452506P 2017-01-31 2017-01-31
US201762527159P 2017-06-30 2017-06-30
US201762527196P 2017-06-30 2017-06-30
PCT/US2017/056638 WO2018071849A2 (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

Publications (2)

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DK3526323T3 DK3526323T3 (da) 2023-06-26
DK3526323T5 true DK3526323T5 (da) 2024-09-02

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US (6) US10662416B2 (enExample)
EP (2) EP3526323B1 (enExample)
JP (5) JP6811857B2 (enExample)
KR (5) KR20230010826A (enExample)
CN (2) CN110023495A (enExample)
AU (3) AU2017342536A1 (enExample)
BR (1) BR112019007450A2 (enExample)
CA (1) CA3040143A1 (enExample)
CL (1) CL2019000993A1 (enExample)
CO (1) CO2019003675A2 (enExample)
CR (1) CR20190181A (enExample)
DK (1) DK3526323T5 (enExample)
DO (1) DOP2019000097A (enExample)
FI (1) FI3526323T3 (enExample)
IL (4) IL265921B2 (enExample)
MA (1) MA46535A (enExample)
MX (2) MX2019004349A (enExample)
PE (1) PE20191353A1 (enExample)
PH (1) PH12019500788A1 (enExample)
SG (2) SG11201903042VA (enExample)
WO (1) WO2018071849A2 (enExample)

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